Search of human proteins with 45243501

Search of human proteins with 45243501

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45243501 BCL2-like 13 (apoptosis facilitator) [Homo sapiens]
         (485 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45243501 BCL2-like 13 (apoptosis facilitator) [Homo sapiens]       939   0.0  
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 48   2e-05
gi|38176300 nestin [Homo sapiens]                                      45   2e-04
gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]                      42   0.001
gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]                      42   0.001
gi|110349719 titin isoform N2-A [Homo sapiens]                         41   0.003
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     41   0.003
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    40   0.006
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    40   0.006
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    40   0.006
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    40   0.006
gi|109637771 calpastatin isoform l [Homo sapiens]                      39   0.011
gi|109637769 calpastatin isoform k [Homo sapiens]                      39   0.011
gi|109637767 calpastatin isoform j [Homo sapiens]                      39   0.011
gi|109637765 calpastatin isoform i [Homo sapiens]                      39   0.011
gi|109637763 calpastatin isoform h [Homo sapiens]                      39   0.011
gi|109637761 calpastatin isoform g [Homo sapiens]                      39   0.011
gi|109637759 calpastatin isoform f [Homo sapiens]                      39   0.011
gi|109637757 calpastatin isoform e [Homo sapiens]                      39   0.011
gi|27765087 calpastatin isoform c [Homo sapiens]                       39   0.011
gi|27765085 calpastatin isoform b [Homo sapiens]                       39   0.011
gi|109637753 calpastatin isoform a [Homo sapiens]                      39   0.011
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              39   0.011
gi|50428935 BPY2 interacting protein 1 [Homo sapiens]                  39   0.014
gi|219802034 nuclear factor related to kappaB binding protein is...    38   0.018
gi|23346420 nuclear factor related to kappaB binding protein iso...    38   0.018
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    37   0.031
gi|83367077 mucin 16 [Homo sapiens]                                    37   0.040
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 37   0.040
gi|4557719 DNA ligase I [Homo sapiens]                                 36   0.069

>gi|45243501 BCL2-like 13 (apoptosis facilitator) [Homo sapiens]
          Length = 485

 Score =  939 bits (2427), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 1   MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK 60
           MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
Sbjct: 1   MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK 60

Query: 61  TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH 120
           TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
Sbjct: 61  TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH 120

Query: 121 KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ 180
           KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ
Sbjct: 121 KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ 180

Query: 181 FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES 240
           FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES
Sbjct: 181 FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES 240

Query: 241 PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN 300
           PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN
Sbjct: 241 PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN 300

Query: 301 NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP 360
           NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP
Sbjct: 301 NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP 360

Query: 361 DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES 420
           DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES
Sbjct: 361 DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES 420

Query: 421 LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL 480
           LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL
Sbjct: 421 LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL 480

Query: 481 ALRKK 485
           ALRKK
Sbjct: 481 ALRKK 485


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 60/258 (23%), Positives = 108/258 (41%), Gaps = 26/258 (10%)

Query: 212  EYPGITAEDSNDIYILPSDNSGQVSPPE---SPTVTTSWQSESLPVSLSAS--------- 259
            E+  ++ ED+ +  +   D++ QVS P    S T     + +SL  ++SAS         
Sbjct: 983  EHTILSDEDTEEAELFSPDSASQVSIPPFRISETEKNELEPDSLLTAVSASGYSCFSEAD 1042

Query: 260  --QSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPE 317
                  T + PVS    S Q+   +   + S   + +   S + S  ++I    K E+P 
Sbjct: 1043 EEDIGSTAATPVSEQFSSSQKQKAETFPLMSPLEDLSLPPSTDKSEKAEI----KPEIPT 1098

Query: 318  GMEEAAVASVVLPARELQEALPEAPAPLLP-HITATSLLGTREPDTEVITVEKSSPATSL 376
                 +   ++   ++ Q  L      L+P H+T+    G RE  + V  +  + PA S 
Sbjct: 1099 TSTSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEVEKGEREASSSVAAIPAALPAQSS 1158

Query: 377  FVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPP 436
             V+ + +     +  P  V  +    EPT  L     + A +E +   LS   +++ VP 
Sbjct: 1159 IVKEETKPASPHSVLPDSVPAIKKEQEPTAAL----TLKAADEQMA--LSKVRKEEIVPD 1212

Query: 437  S-EGKSRLSPAGEMKPMP 453
            S E  + +S   +M+P P
Sbjct: 1213 SQEATAHVSQDQKMEPQP 1230


>gi|38176300 nestin [Homo sapiens]
          Length = 1621

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 83/328 (25%), Positives = 137/328 (41%), Gaps = 33/328 (10%)

Query: 25  LLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSLDKEISEAFTSTGFD 84
           L + EK  ++ L SP+           D+E L  +  E +E L+SL+ E  EAF S    
Sbjct: 667 LTALEKENQEPLRSPEVG---------DEEALRPLTKENQEPLRSLEDENKEAFRSLE-K 716

Query: 85  RHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTLETT 144
            +  P+ +    + S+   L     K  + L+E   + L+ L  +  T Q  R    +  
Sbjct: 717 ENQEPLKTLEEEDQSIVRPLETENHKSLRSLEEQDQETLRTL--EKETQQRRRSLGEQDQ 774

Query: 145 VHASGWNKI-LVPLVLLRQMLLE-LTRRGQEPLSALLQFGVTYLEDYSAEYI--IQQGGW 200
           +      K+ L PL  L Q +   L    QE L +L +  V  ++    E +  ++  G 
Sbjct: 775 MTLRPPEKVDLEPLKSLDQEIARPLENENQEFLKSLKEESVEAVKSLETEILESLKSAGQ 834

Query: 201 GTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTV---TTSWQSESLPVSLS 257
             + +L+S E + P  T E+ N   + P +   Q  P ES  V   T     E    SL 
Sbjct: 835 ENLETLKSPETQAPLWTPEEINQGAMNPLEKEIQ-EPLESVEVNQETFRLLEEENQESLR 893

Query: 258 ASQSWHTESL--PVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEV 315
           +  +W+ E+L  P  +  ES + +    EE ++L   G GE  E+  S    +  E +E+
Sbjct: 894 SLGAWNLENLRSPEEVDKESQRNL----EEEENL---GKGEYQESLRS----LEEEGQEL 942

Query: 316 PEGMEEAAVASVVLPARELQEALPEAPA 343
           P+  +       V   +EL +  P   A
Sbjct: 943 PQSADVQRWEDTVEKDQELAQESPPGMA 970


>gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]
          Length = 327

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 17/119 (14%)

Query: 102 DCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTL----------ETTVHASGWN 151
           + L + G+++ ++LK+   KAL       ++Y  F+  T           E+ V A G+ 
Sbjct: 214 ELLKYSGDQLERKLKKD--KALMGHFQDGLSYSVFKTITDQVLMGVDPRGESEVKAQGFK 271

Query: 152 KILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEE 210
             LV  V  +     LT     P++ +L FG  YL++  + +I Q GGW  +  +  EE
Sbjct: 272 AALVIDVTAK-----LTAIDNHPMNRVLGFGTKYLKENFSPWIQQHGGWEKILGISHEE 325


>gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]
          Length = 327

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 17/119 (14%)

Query: 102 DCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTL----------ETTVHASGWN 151
           + L + G+++ ++LK+   KAL       ++Y  F+  T           E+ V A G+ 
Sbjct: 214 ELLKYSGDQLERKLKKD--KALMGHFQDGLSYSVFKTITDQVLMGVDPRGESEVKAQGFK 271

Query: 152 KILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEE 210
             LV  V  +     LT     P++ +L FG  YL++  + +I Q GGW  +  +  EE
Sbjct: 272 AALVIDVTAK-----LTAIDNHPMNRVLGFGTKYLKENFSPWIQQHGGWEKILGISHEE 325


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 61/227 (26%), Positives = 89/227 (39%), Gaps = 20/227 (8%)

Query: 239   ESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKS 298
             E+P      + E +PV ++  Q          + PE  +++  + EEV   +     E+ 
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEV-LFEEEIVPE--EEVLPEEEEVLPEEEEVLPEEE 10138

Query: 299   ENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARE-LQEALPEAPAPL-LPHITATSLLG 356
             E      +I   E+EEVP   E        +P  E L E  P+ P P  +P I       
Sbjct: 10139 EVLPEEEEIPP-EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKK---- 10193

Query: 357   TREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINA 416
               E    +   E++ PA    V    EE +    +  EV  V    EP E  +SE+EI  
Sbjct: 10194 VTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE 10253

Query: 417   REESL--VEELSPASE----KKPVP----PSEGKSRLSPAGEMKPMP 453
                S+  VEE++P       KK VP    P   K    PA   K +P
Sbjct: 10254 EPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIP 10300



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 19/162 (11%)

Query: 311   EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS 370
             EK +VPE +E   +  V    +++++ LPE        +   S+L  R P+ E   VE  
Sbjct: 10910 EKPQVPEKVELTPL-KVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR-PEEEEPKVEPK 10967

Query: 371   SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPA-- 428
                        E+  K A  EP   + V     PT T   ++E    E + V E+ PA  
Sbjct: 10968 KL---------EKVKKPAVPEPPPPKPVEEVEVPTVT---KRERKIPEPTKVPEIKPAIP 11015

Query: 429   ---SEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAA 467
                 E KP P +E K+   P  E +P P++   ++ + G  A
Sbjct: 11016 LPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 11057



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 310  VEKEEVPEGMEEAAVASVVLPARELQ-EALPEAPAPLLPHITATSLLGTREPDTEVITVE 368
            ++ E  P  + ++ V    +P R +  E +P   AP +P +  T     ++P  + I V 
Sbjct: 8928 IKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTP--EEKKPPPKRIEVT 8985

Query: 369  KSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPA 428
            K +      V+ D ++V A   E T  EE+V    P  TL     I A+   +++  S A
Sbjct: 8986 KKA------VKKDAKKVVAKPKEMTPREEIVKKPPPPTTL-----IPAKAPEIIDVSSKA 9034

Query: 429  SEKK 432
             E K
Sbjct: 9035 EEVK 9038



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 9/116 (7%)

Query: 339   PEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEV 398
             PE P   +P +   ++   + P  E I  +  SP   +F E +E  ++    E   VEE 
Sbjct: 10630 PEVPPTKVPEVPKVAVPEKKVP--EAIPPKPESPPPEVFEEPEEVALEEPPAEV--VEEP 10685

Query: 399   VPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPL 454
              PA  P  T+  +K +  ++   V    P  E  PV   E    + P    K +PL
Sbjct: 10686 EPAAPPQVTVPPKKPVPEKKAPAVVAKKP--ELPPVKVPEVPKEVVPE---KKVPL 10736



 Score = 30.0 bits (66), Expect = 4.9
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 20/115 (17%)

Query: 330  PARELQEALPE--APAPLLPHITATSLLGTREPDTEV-----ITVEK------SSPATSL 376
            PA+ L++A+PE   P P+   +         EP         I++ K      + PA  +
Sbjct: 9811 PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKV 9870

Query: 377  FVE----LDEEEVKAATTE---PTEVEEVVPALEPTETLLSEKEINAREESLVEE 424
             ++    + EE+V     E   P  V EV   LEP E    E+ +   EE LVEE
Sbjct: 9871 PMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEE 9925



 Score = 30.0 bits (66), Expect = 4.9
 Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 16/147 (10%)

Query: 308   VHVEKEEVPEGMEEAAVASVVLPARELQEALP---EAPAPLLPHITATSLLGTREPDTEV 364
             V + K+E P   +   V    +P  ++   +P   EAP   +P +    +   + P    
Sbjct: 9991  VLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050

Query: 365   ITVEKSSPATSLFVELDEEEVKAATTEPTEVE----------EVVP---ALEPTETLLSE 411
               VE          +    E K  T  P +VE          E VP   AL   E +L E
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110

Query: 412   KEINAREESLVEELSPASEKKPVPPSE 438
             +EI   EE L EE     E++ V P E
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEE 10137



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 37/144 (25%), Positives = 52/144 (36%), Gaps = 9/144 (6%)

Query: 306   DIVHVEKEEVPEGMEEAAVASV--VLPARELQEALPEAPAPLLPH--ITATSLLGTREPD 361
             ++    KE VPE    AA      V P +     +PEAP  ++P   +          P 
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVK-----VPEAPKEVVPEKKVPVPPPKKPEVPP 10634

Query: 362   TEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESL 421
             T+V  V K +       E    + ++   E  E  E V   EP   ++ E E  A  +  
Sbjct: 10635 TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT 10694

Query: 422   VEELSPASEKKPVPPSEGKSRLSP 445
             V    P  EKK       K  L P
Sbjct: 10695 VPPKKPVPEKKAPAVVAKKPELPP 10718



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 35/150 (23%), Positives = 56/150 (37%), Gaps = 20/150 (13%)

Query: 307   IVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVIT 366
             +  V KE VPE         V +P +      PE P   +P +    +L   E     + 
Sbjct: 10749 VPEVPKEVVPE-------KKVAVPKK------PEVPPAKVPEVPKKPVL--EEKPAVPVP 10793

Query: 367   VEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELS 426
                 SP   ++ E   EE+        E E+ VP  E  E  +    +    + ++ E  
Sbjct: 10794 ERAESPPPEVYEE--PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKK 10851

Query: 427   PASEKKP--VPPSEGK-SRLSPAGEMKPMP 453
                 KKP   PP E +  ++    ++KP P
Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRP 10881


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 46/178 (25%), Positives = 66/178 (37%), Gaps = 10/178 (5%)

Query: 284 EEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPA 343
           EE  S +        E   S ++    EKEE     E  +      PA+E  ++ PEA +
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS 566

Query: 344 PLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVV--PA 401
           P      + + + + E        E  SPA +   E  +  VK     P E +  V   A
Sbjct: 567 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626

Query: 402 LEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKS 459
             P E    EK   A+  +  E  SP   K P    E +   SP     P+  +E KS
Sbjct: 627 KSPAEVKSPEK---AKSPTKEEAKSPEKAKSP----EKEEAKSPEKAKSPVK-AEAKS 676



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 372 PATSLFVELDEEE----VKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSP 427
           P+ S  +++  EE    V+ +  E   VEE     + TE +  E+E  A+EE   EE   
Sbjct: 430 PSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGG 489

Query: 428 ASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKS 459
             E+      E K   SP  E    P  E KS
Sbjct: 490 EEEEAEGGEEETK---SPPAEEAASPEKEAKS 518



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 40/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)

Query: 280 AMDPEEVKSLDSNGAGEKS---ENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQE 336
           A  PE+ K+LD      K+   E   S +D    EK + P   E  +      P +E  +
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPAD-KFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808

Query: 337 ALPEAPAPLLPHITATSLLGTREPDTEVI-----TVEKSSPATSLFVELDEEEVKAATTE 391
           A PE   P    + +      +  + +V        E+ +PAT    E  + + + A  +
Sbjct: 809 A-PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKK 867

Query: 392 PTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKP 451
                +V    EP      E ++ A++E   ++     +K P P  E  +++    + KP
Sbjct: 868 EAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK-----KKVPTPEKEAPAKVEVKEDAKP 922

Query: 452 MPLSE 456
              +E
Sbjct: 923 KEKTE 927


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 34/204 (16%)

Query: 270 SLGPESWQQIAMDPEEVKSLDSNGAGEK------------SENNSSNSDIVHVE-KEEV- 315
           S  P +   +  + EE  S+ + GA  K            SE+ SS+SD   VE K  V 
Sbjct: 160 SAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK 219

Query: 316 PEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATS 375
           P  ++ ++V++   PAR+       APAP          +G   P  +   +  +  A  
Sbjct: 220 PAQVKASSVSTKESPARKA------APAP--------GKVGDVTPQVKGGALPPAKRAKK 265

Query: 376 LFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVP 435
                  EE   ++ E +E EE  PA   ++   SEK +  R  S   + +P     P P
Sbjct: 266 ------PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319

Query: 436 PSEGKSRLSPAGEMKPMPLSEGKS 459
           P +  +  S     KP   SE  S
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSS 343


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 34/204 (16%)

Query: 270 SLGPESWQQIAMDPEEVKSLDSNGAGEK------------SENNSSNSDIVHVE-KEEV- 315
           S  P +   +  + EE  S+ + GA  K            SE+ SS+SD   VE K  V 
Sbjct: 160 SAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK 219

Query: 316 PEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATS 375
           P  ++ ++V++   PAR+       APAP          +G   P  +   +  +  A  
Sbjct: 220 PAQVKASSVSTKESPARKA------APAP--------GKVGDVTPQVKGGALPPAKRAKK 265

Query: 376 LFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVP 435
                  EE   ++ E +E EE  PA   ++   SEK +  R  S   + +P     P P
Sbjct: 266 ------PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319

Query: 436 PSEGKSRLSPAGEMKPMPLSEGKS 459
           P +  +  S     KP   SE  S
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSS 343


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 34/204 (16%)

Query: 270 SLGPESWQQIAMDPEEVKSLDSNGAGEK------------SENNSSNSDIVHVE-KEEV- 315
           S  P +   +  + EE  S+ + GA  K            SE+ SS+SD   VE K  V 
Sbjct: 160 SAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK 219

Query: 316 PEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATS 375
           P  ++ ++V++   PAR+       APAP          +G   P  +   +  +  A  
Sbjct: 220 PAQVKASSVSTKESPARKA------APAP--------GKVGDVTPQVKGGALPPAKRAKK 265

Query: 376 LFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVP 435
                  EE   ++ E +E EE  PA   ++   SEK +  R  S   + +P     P P
Sbjct: 266 ------PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319

Query: 436 PSEGKSRLSPAGEMKPMPLSEGKS 459
           P +  +  S     KP   SE  S
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSS 343


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 34/204 (16%)

Query: 270 SLGPESWQQIAMDPEEVKSLDSNGAGEK------------SENNSSNSDIVHVE-KEEV- 315
           S  P +   +  + EE  S+ + GA  K            SE+ SS+SD   VE K  V 
Sbjct: 160 SAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK 219

Query: 316 PEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATS 375
           P  ++ ++V++   PAR+       APAP          +G   P  +   +  +  A  
Sbjct: 220 PAQVKASSVSTKESPARKA------APAP--------GKVGDVTPQVKGGALPPAKRAKK 265

Query: 376 LFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVP 435
                  EE   ++ E +E EE  PA   ++   SEK +  R  S   + +P     P P
Sbjct: 266 ------PEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAP 319

Query: 436 PSEGKSRLSPAGEMKPMPLSEGKS 459
           P +  +  S     KP   SE  S
Sbjct: 320 PGKAGAVASQTKAGKPEEDSESSS 343


>gi|109637771 calpastatin isoform l [Homo sapiens]
          Length = 654

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 334 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 393

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 394 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 452

Query: 447 GE 448
            E
Sbjct: 453 SE 454



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 252 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 311

Query: 439 GK 440
            +
Sbjct: 312 SE 313


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 353 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 412

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 413 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 471

Query: 447 GE 448
            E
Sbjct: 472 SE 473



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 271 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 330

Query: 439 GK 440
            +
Sbjct: 331 SE 332


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 347 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 406

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 407 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 465

Query: 447 GE 448
            E
Sbjct: 466 SE 467



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 265 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 324

Query: 439 GK 440
            +
Sbjct: 325 SE 326


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 388 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 447

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 448 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 506

Query: 447 GE 448
            E
Sbjct: 507 SE 508



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 306 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 365

Query: 439 GK 440
            +
Sbjct: 366 SE 367


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 449 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 508

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 509 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 567

Query: 447 GE 448
            E
Sbjct: 568 SE 569



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 367 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 426

Query: 439 GK 440
            +
Sbjct: 427 SE 428


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 452 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 511

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 512 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 570

Query: 447 GE 448
            E
Sbjct: 571 SE 572



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 370 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 429

Query: 439 GK 440
            +
Sbjct: 430 SE 431


>gi|109637759 calpastatin isoform f [Homo sapiens]
          Length = 750

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 430 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 489

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 490 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 548

Query: 447 GE 448
            E
Sbjct: 549 SE 550



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 348 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 407

Query: 439 GK 440
            +
Sbjct: 408 SE 409


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 436 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 495

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 496 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 554

Query: 447 GE 448
            E
Sbjct: 555 SE 556



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 354 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 413

Query: 439 GK 440
            +
Sbjct: 414 SE 415


>gi|27765087 calpastatin isoform c [Homo sapiens]
          Length = 430

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 111 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 170

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 171 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 229

Query: 447 GE 448
            E
Sbjct: 230 SE 231


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 366 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 425

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 426 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 484

Query: 447 GE 448
            E
Sbjct: 485 SE 486



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 284 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 343

Query: 439 GK 440
            +
Sbjct: 344 SE 345


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP---ATSLFVELDEEEVK 386
           P  + +E+   APAP+   +  TS+   +    E  T++ + P     +L   L ++E  
Sbjct: 471 PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEAD 530

Query: 387 AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPA 446
               +P   +    A E     L EKE     +  +EE+    + KP+ P E K +L P 
Sbjct: 531 PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKD-KDGKPLLPKESKEQLPPM 589

Query: 447 GE 448
            E
Sbjct: 590 SE 591



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 379 ELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSE 438
           ELD   +K       + E++    E  ET+ SE  +    +   + L P  E+KP P SE
Sbjct: 389 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 448

Query: 439 GK 440
            +
Sbjct: 449 SE 450


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 65/297 (21%), Positives = 107/297 (36%), Gaps = 51/297 (17%)

Query: 202  TVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSA--- 258
            +V +LE+E E+ P     ++ +      +  GQ  P      +   + E+ P S      
Sbjct: 1921 SVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEAL 1980

Query: 259  -----SQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKE 313
                 +Q    E+ P S   E+ +      E  +       G +++  S   +   VE E
Sbjct: 1981 EVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGE 2040

Query: 314  ---------------EVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTR 358
                           E PE  EEA  A       E+QEA  EA  P    + A    G  
Sbjct: 2041 TQKTEGDAQPESDGVEAPEAEEEAQEAE-----GEVQEAEGEA-HPESEDVDAQEAEGEA 2094

Query: 359  EPDTEVITVEKS-----------SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTET 407
            +P++E +   ++           +P T    + + E ++A    P    E  P  E  E 
Sbjct: 2095 QPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEA----PEAEGEAQPESEGVEA 2150

Query: 408  LLSEKEINAREESL-----VEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKS 459
              +E E     E +      EE  P  E    P +EG+++  P  E    P +EG++
Sbjct: 2151 QDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQ--PESEGIEAPEAEGEA 2205



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 43/167 (25%), Positives = 60/167 (35%), Gaps = 21/167 (12%)

Query: 274  ESWQQIAMDPEEVKSLDSNGAGEKS-------ENNSSNSDIVHVEKEEVPEGMEEAAVAS 326
            E  Q+  +  EE K  +  G  E+        E          V+ EEV EG E      
Sbjct: 1329 EGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGG---- 1384

Query: 327  VVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVK 386
              L    L+E L E   P    +    L     PD +    ++  P     V+ +E    
Sbjct: 1385 --LQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGK--GSQEDDP-----VQEEEAGRA 1435

Query: 387  AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKP 433
            +A+ EP   E      EP   L SE + +A E     +L P  EK P
Sbjct: 1436 SASAEPCPAEGTEEPTEPPSHL-SETDPSASERQSGSQLEPGLEKPP 1481



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 33/247 (13%)

Query: 207  ESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTES 266
            E E +E  G    +S D+    ++  G+  P          + E+       +     E+
Sbjct: 2068 EGEVQEAEGEAHPESEDVDAQEAE--GEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEA 2125

Query: 267  LPVSLG---PESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPE--GMEE 321
             P S G   PE+  +   + E V++ D+ G   +++  S   +    E+E  PE  G+E 
Sbjct: 2126 QPESEGIEAPEAEGEAQPESEGVEAQDAEG---EAQPESEGIEAQEAEEEAQPELEGVEA 2182

Query: 322  AAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELD 381
                    P  E  EA PEA     P +      G   P+ E    E++ P     VE  
Sbjct: 2183 PEAEGEAQPESEGIEA-PEAEGEAQPELE-----GVEAPEAE----EEAQPEPE-GVETP 2231

Query: 382  EEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKS 441
            E E +A      E +       P  +L   +   A E S     SP  E +P PP     
Sbjct: 2232 EAEGEAQPESEGETQGEKKG-SPQVSLGDGQSEEASESS-----SPVPEDRPTPPP---- 2281

Query: 442  RLSPAGE 448
              SP G+
Sbjct: 2282 --SPGGD 2286



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 44/233 (18%), Positives = 81/233 (34%), Gaps = 35/233 (15%)

Query: 207  ESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTES 266
            E + +E  G    +S D+    ++   Q    +  T    W+ +  P S  A        
Sbjct: 1857 EGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQ--PESEGAE------- 1907

Query: 267  LPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVAS 326
                  PE+ ++   + E V++L++ G  E     +   +     +E   +   E+ V  
Sbjct: 1908 -----APEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVI- 1961

Query: 327  VVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVK 386
                  E QEA  EA                   D E + VE  +       + + E+V+
Sbjct: 1962 ------ESQEAEEEAQP--------------ESEDVEALEVEVETQEAEGEAQPESEDVE 2001

Query: 387  AATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEG 439
            A   E    E    A   ++ + ++ +    E   VE  +  +E    P S+G
Sbjct: 2002 APEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054


>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
          Length = 1059

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 65/282 (23%), Positives = 102/282 (36%), Gaps = 43/282 (15%)

Query: 218 AEDSNDIYILPSDNSGQVSPPESPTVTT-SWQSESLPVSLSASQSWHT-ESLPVSLGPES 275
           AE S  + + P    G+  P  SPTVTT +  + SLP  + +  S    ESL VS   + 
Sbjct: 648 AEGSERLSLSPL-RGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSF-EQV 705

Query: 276 WQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVE------KEEVPEGMEEAAVASV-- 327
               A   E   SL   G   +   +  + D+  V       ++ VP     A+  S   
Sbjct: 706 LPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSND 765

Query: 328 ---------------VLPARELQEALPEA----PAPLLPHITATSLLGTREPDTEVITVE 368
                            P   + E+LP      P PL P    +      + DTE   V 
Sbjct: 766 SSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADS------DEDTEGFGVP 819

Query: 369 KSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPA 428
           +  P        D  +V     +P+ +  V P + P +T    + ++   + L    S A
Sbjct: 820 RHDPLP------DPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRA 873

Query: 429 SEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVA 470
           +  K  P +  K++    G+    PLS        GG A ++
Sbjct: 874 AAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLS 915


>gi|219802034 nuclear factor related to kappaB binding protein
           isoform 1 [Homo sapiens]
          Length = 1299

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 51/219 (23%), Positives = 82/219 (37%), Gaps = 21/219 (9%)

Query: 236 SPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAG 295
           S   S  V +S  SE   +SLS S    T   PV+    +   I + P  V +++ +G  
Sbjct: 690 SKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNKSGPS 749

Query: 296 EKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLL 355
             SE   S+S ++ V    +P       + +++ PA        +A A ++ H  +  L 
Sbjct: 750 TVSEPAKSSSGVLLVSSPTMPH------LGTMLSPASSQTAPSSQAAARVVSHSGSAGLS 803

Query: 356 GTR---EPDTEVITVEKSSPATSL--FVELDEEEVKAATTEPTEVEEVVPALEPTETLLS 410
             R   +P    +  +   PA +L       +  V A  T+   V + V A  P +   +
Sbjct: 804 QVRVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTKVVPQTVMATVPVKAQTT 863

Query: 411 EKEI--------NAREESLVEELSPASEKKPVPPSEGKS 441
              +             SL    SP S  KP   S G S
Sbjct: 864 AATVQRPGPGQTGLTVTSLPATASPVS--KPATSSPGTS 900


>gi|23346420 nuclear factor related to kappaB binding protein
           isoform 2 [Homo sapiens]
          Length = 1324

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 51/219 (23%), Positives = 82/219 (37%), Gaps = 21/219 (9%)

Query: 236 SPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAG 295
           S   S  V +S  SE   +SLS S    T   PV+    +   I + P  V +++ +G  
Sbjct: 715 SKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNKSGPS 774

Query: 296 EKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLL 355
             SE   S+S ++ V    +P       + +++ PA        +A A ++ H  +  L 
Sbjct: 775 TVSEPAKSSSGVLLVSSPTMPH------LGTMLSPASSQTAPSSQAAARVVSHSGSAGLS 828

Query: 356 GTR---EPDTEVITVEKSSPATSL--FVELDEEEVKAATTEPTEVEEVVPALEPTETLLS 410
             R   +P    +  +   PA +L       +  V A  T+   V + V A  P +   +
Sbjct: 829 QVRVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTKVVPQTVMATVPVKAQTT 888

Query: 411 EKEI--------NAREESLVEELSPASEKKPVPPSEGKS 441
              +             SL    SP S  KP   S G S
Sbjct: 889 AATVQRPGPGQTGLTVTSLPATASPVS--KPATSSPGTS 925


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 43/170 (25%), Positives = 60/170 (35%), Gaps = 28/170 (16%)

Query: 284  EEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPA 343
            EE +  +     E  E      +    E EE  E +EE           E++E  P  P 
Sbjct: 922  EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT 981

Query: 344  --PLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDE---EEVKAATTEPTEVEEV 398
              P LP            P++      +  P   L +E++E   EE + A T PT   E 
Sbjct: 982  LPPALP-----------PPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA 1030

Query: 399  VP------------ALEPTETLLSEKEINAREESLVEELSPASEKKPVPP 436
            +P            A  P    L E+E +A    L EE    S+K   PP
Sbjct: 1031 LPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 37.0 bits (84), Expect = 0.040
 Identities = 47/243 (19%), Positives = 88/243 (36%), Gaps = 41/243 (16%)

Query: 205  SLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHT 264
            S+ +E   +  IT   +ND+  +   N        SP+        +LP S++ +  WH+
Sbjct: 4709 SVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHS 4768

Query: 265  ESLPVSLGPESWQQIAMDPEEV-KSLDSNGAGEKSENN--------SSNSDIVHVEKEEV 315
             S PVS+       +     +V  SL++  +  +S +N        S+ +  +      +
Sbjct: 4769 TSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSI 4828

Query: 316  PEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATS 375
               +           +     A PE      P++T +++        E  T+ +S P +S
Sbjct: 4829 NTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTM--------EDTTISRSIPKSS 4880

Query: 376  LFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVP 435
                      K   TE      + P L              RE S+ +E++ ++E   VP
Sbjct: 4881 ----------KTTRTETETTSSLTPKL--------------RETSISQEITSSTETSTVP 4916

Query: 436  PSE 438
              E
Sbjct: 4917 YKE 4919



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 23/134 (17%)

Query: 234  QVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNG 293
            Q SPPES + +T     S  +S   + S  T+  P S              EV +L   G
Sbjct: 5272 QASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYS--------------EVTTLMGMG 5317

Query: 294  AGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPL--LPH--- 348
             G  S   +   +    E   V   M   A+ S    +    +++P +P P+  LP    
Sbjct: 5318 PGNVSWMTTPPVE----ETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVL 5373

Query: 349  ITATSLLGTREPDT 362
            +T T +LGT  P++
Sbjct: 5374 VTTTDVLGTTSPES 5387



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 51/205 (24%), Positives = 79/205 (38%), Gaps = 27/205 (13%)

Query: 240  SPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSE 299
            SP +T+S      PVS +   S H+ SLPV+          +    VK+ +  G   + E
Sbjct: 9150 SPVMTSS-----SPVSSTLPDSIHSSSLPVT--------SLLTSGLVKTTELLGTSSEPE 9196

Query: 300  NNS----SNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPH---ITAT 352
             +S    S++    +   EV    E+  + +VV           E+P+ +L       AT
Sbjct: 9197 TSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSG-----YTHESPSSVLADSVTTKAT 9251

Query: 353  SLLGTREP--DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLS 410
            S +G   P  DT V+T   +   TS      +  +     E +  EE   A E +  L S
Sbjct: 9252 SSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSS 9311

Query: 411  EKEINAREESLVEELSPASEKKPVP 435
                   E S  E +S +    P P
Sbjct: 9312 VPTGATTEVSRTEAISSSRTSIPGP 9336


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 37.0 bits (84), Expect = 0.040
 Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 7/125 (5%)

Query: 339 PEAPAPLLPHITATSLLGTREPDTEV----ITVEKSSPATSLFVELDEEEVKAATTEPTE 394
           P AP P  P ++  S     EP  E+         S  AT L+ E   E      +EP  
Sbjct: 36  PPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAP 95

Query: 395 VEEVVPALEPTETLLSEKEINAREESLVEEL-SPASEKKPVPPSEGKSRLSP--AGEMKP 451
                PA EP      E       ES  E    PA E  P P  E    ++P  A E  P
Sbjct: 96  EPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTP 155

Query: 452 MPLSE 456
            P++E
Sbjct: 156 EPVTE 160


>gi|4557719 DNA ligase I [Homo sapiens]
          Length = 919

 Score = 36.2 bits (82), Expect = 0.069
 Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 19/175 (10%)

Query: 270 SLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVL 329
           +L P   Q+ A+D  +V            ENN+S SD   ++    P G+ +   A   L
Sbjct: 74  ALSPAKGQKPALDCSQVSP---PRPATSPENNASLSDTSPMDSS--PSGIPKRRTARKQL 128

Query: 330 PARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAAT 389
           P R +QE L E                 ++ + E  T ++S     +  E + E+    T
Sbjct: 129 PKRTIQEVLEEQSE------DEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPT 182

Query: 390 TEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLS 444
           T P  + +   A  PTE+ +SE E+  ++E L EE     E++  PP      LS
Sbjct: 183 TPPKPL-KTSKAETPTES-VSEPEVATKQE-LQEE-----EEQTKPPRRAPKTLS 229


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.125    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,924,107
Number of Sequences: 37866
Number of extensions: 1022322
Number of successful extensions: 4881
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 217
Number of HSP's that attempted gapping in prelim test: 4514
Number of HSP's gapped (non-prelim): 563
length of query: 485
length of database: 18,247,518
effective HSP length: 106
effective length of query: 379
effective length of database: 14,233,722
effective search space: 5394580638
effective search space used: 5394580638
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.