Guide to the Human Genome
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Name: LIG1 Sequence: fasta or formatted (919aa) NCBI GI: 4557719
Description:

DNA ligase I

Referenced in:

DNases, Recombination, and DNA Repair
Replication Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         76           2
 C cysteine            1.2         11           1
 D aspartate           5.2         48           1
 E glutamate          10.9        100           6
 F phenylalanine       2.7         25           2
 G glycine             6.2         57           2
 H histidine           1.3         12           2
 I isoleucine          3.8         35           2
 K lysine              7.7         71           2
 L leucine             9.6         88           2
 M methionine          1.0          9           1
 N asparagine          1.7         16           2
 P proline             7.8         72           4
 Q glutamine           4.6         42           2
 R arginine            6.3         58           3
 S serine              7.8         72           2
 T threonine           4.9         45           2
 V valine              6.2         57           2
 W tryptophan          0.8          7           1
 Y tyrosine            2.0         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA ligase I 
LIG3                  0.084   ligase III, DNA, ATP-dependent isoform beta precurso...
LIG3                  0.084   ligase III, DNA, ATP-dependent isoform alpha precurs...
LIG4                  0.055   DNA ligase IV 
LIG4                  0.055   DNA ligase IV 
LIG4                  0.055   DNA ligase IV 
NEFH                  0.028   neurofilament, heavy polypeptide 200kDa 
NEFM                  0.023   neurofilament, medium polypeptide 150kDa isoform 1 ...
NEFM                  0.023   neurofilament, medium polypeptide 150kDa isoform 2 ...
NOLC1                 0.022   nucleolar and coiled-body phosphoprotein 1 
EIF5B                 0.020   eukaryotic translation initiation factor 5B 
HDGF2                 0.020   hepatoma-derived growth factor-related protein 2 iso...
HDGF2                 0.020   hepatoma-derived growth factor-related protein 2 iso...
TULP1                 0.018   tubby like protein 1 
MAP1B                 0.018   microtubule-associated protein 1B 
C14orf174             0.018   hypothetical protein LOC161394 
ZC3H18                0.017   zinc finger CCCH-type containing 18 
TCOF1                 0.016   Treacher Collins-Franceschetti syndrome 1 isoform e...
TCOF1                 0.016   Treacher Collins-Franceschetti syndrome 1 isoform d...
TCOF1                 0.016   Treacher Collins-Franceschetti syndrome 1 isoform a ...
TCOF1                 0.016   Treacher Collins-Franceschetti syndrome 1 isoform c ...
TXNDC2                0.015   thioredoxin domain-containing 2 isoform 1 
TXNDC2                0.015   thioredoxin domain-containing 2 isoform 2 
TXNDC2                0.015   thioredoxin domain-containing 2 isoform 1 
FSCB                  0.015   fibrous sheath CABYR binding protein 
TTN                   0.015   titin isoform N2-A 
AKAP12                0.015   A kinase (PRKA) anchor protein 12 isoform 1 
AKAP12                0.015   A kinase (PRKA) anchor protein 12 isoform 2 
ANK2                  0.015   ankyrin 2 isoform 1 
SRRM2                 0.015   splicing coactivator subunit SRm300 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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