BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] (255 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] 509 e-144 gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] 488 e-138 gi|23110942 proteasome alpha 5 subunit [Homo sapiens] 126 2e-29 gi|4506189 proteasome alpha 7 subunit [Homo sapiens] 125 3e-29 gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] 122 4e-28 gi|23110944 proteasome alpha 6 subunit [Homo sapiens] 117 1e-26 gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] 115 4e-26 gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] 111 5e-25 gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 111 7e-25 gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 111 7e-25 gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] 97 1e-20 gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] 97 1e-20 gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] 81 1e-15 gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] 77 2e-14 gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] 63 2e-10 gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] 60 2e-09 gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] 60 2e-09 gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] 60 2e-09 gi|4504211 guanylate cyclase 1, soluble, alpha 2 [Homo sapiens] 33 0.24 gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 30 1.6 gi|50428925 cytoskeleton associated protein 1 [Homo sapiens] 30 1.6 gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 30 2.0 gi|115529463 protein kinase D1 [Homo sapiens] 28 5.9 gi|55749742 HEAT repeat containing 5B [Homo sapiens] 28 5.9 gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 28 5.9 gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 28 5.9 gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 28 7.8 gi|23308729 zinc finger protein 268 [Homo sapiens] 28 7.8 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 28 7.8 gi|157671915 guanylate binding protein family, member 6 [Homo sa... 28 7.8 >gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] Length = 255 Score = 509 bits (1310), Expect = e-144 Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE Sbjct: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60 Query: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV Sbjct: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120 Query: 121 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 180 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL Sbjct: 121 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 180 Query: 181 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 240 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA Sbjct: 181 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 240 Query: 241 KESLKEEDESDDDNM 255 KESLKEEDESDDDNM Sbjct: 241 KESLKEEDESDDDNM 255 >gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] Length = 248 Score = 488 bits (1256), Expect = e-138 Identities = 248/255 (97%), Positives = 248/255 (97%), Gaps = 7/255 (2%) Query: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE Sbjct: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60 Query: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV Sbjct: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120 Query: 121 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 180 HAYTLYSAVRPFGC SVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL Sbjct: 121 HAYTLYSAVRPFGC-------SVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 173 Query: 181 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 240 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA Sbjct: 174 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 233 Query: 241 KESLKEEDESDDDNM 255 KESLKEEDESDDDNM Sbjct: 234 KESLKEEDESDDDNM 248 >gi|23110942 proteasome alpha 5 subunit [Homo sapiens] Length = 241 Score = 126 bits (317), Expect = 2e-29 Identities = 76/215 (35%), Positives = 121/215 (56%), Gaps = 7/215 (3%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD +TFSP+GR+FQVEYA++A++ STAIGI+ +GV VEK + S L E S +++ Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 +D H+G A++GL+ADA++L D AR E N + + ++ + V+ + Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127 Query: 128 A-----VRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQM 182 A RPFG + + G G QL+ +DPSG AIG A + A++ ++++ Sbjct: 128 ADPGAMSRPFGVALLFGGVD-EKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYH 186 Query: 183 KEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWV 217 K MT ++ +K I+ V +E K A +EL+ V Sbjct: 187 KSMTLKEAIKSSLIILKQVMEE-KLNATNIELATV 220 >gi|4506189 proteasome alpha 7 subunit [Homo sapiens] Length = 248 Score = 125 bits (315), Expect = 3e-29 Identities = 79/250 (31%), Positives = 137/250 (54%), Gaps = 18/250 (7%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + + FSPDG +FQVEYA +AV+ STA+G+R +D VV GVEK ++KL +E + +++ Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 +D +V MA AGL ADAR + + AR E + R + ++++ +A YT + Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 Query: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK------LQ 181 RPFG S ++ + + +LY DPSG + + AIG+ ++ + +EK ++ Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182 Query: 182 MKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAK 241 ++T + ++K + +++ + K EL + R + + EE EKY Sbjct: 183 TDDLTIKLVIKALLEVV-----QSGGKNIELAVM-------RRDQSLKILNPEEIEKYVA 230 Query: 242 ESLKEEDESD 251 E KE++E++ Sbjct: 231 EIEKEKEENE 240 >gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] Length = 250 Score = 122 bits (305), Expect = 4e-28 Identities = 79/245 (32%), Positives = 135/245 (55%), Gaps = 8/245 (3%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + + FSPDG +FQVEYA +AV+ STA+GIR + VV GVEK ++KL +E + +++ Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKI 64 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 +D HV MA AGL ADAR + + AR E + + + ++++ +A YT + Sbjct: 65 CALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 124 Query: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 187 RPFG S ++ + + ++LY DPSG + + AIG++ + + +EK ++ Sbjct: 125 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 184 Query: 188 RDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 246 D E K+ I + + V+ +EL+ + R++ + +E E Y E KE Sbjct: 185 SD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYVTEIEKE 237 Query: 247 EDESD 251 ++E++ Sbjct: 238 KEEAE 242 >gi|23110944 proteasome alpha 6 subunit [Homo sapiens] Length = 246 Score = 117 bits (293), Expect = 1e-26 Identities = 62/179 (34%), Positives = 97/179 (54%), Gaps = 1/179 (0%) Query: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSS-TAIGIRCKDGVVFGVEKLVLSKLYEEGSNK 65 G+D + FSP+GR++QVEYA KA+ T++ +R KD V +K V KL + + Sbjct: 8 GFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVT 67 Query: 66 RLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTL 125 LF + ++G + G+ AD+RS AR EA+N++ +GY IP+ L R+A YT Sbjct: 68 HLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQ 127 Query: 126 YSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKE 184 + +RP GC +L G Q+Y DP+G G+ A G + + + +EK K+ Sbjct: 128 NAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186 >gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] Length = 256 Score = 115 bits (288), Expect = 4e-26 Identities = 79/251 (31%), Positives = 135/251 (53%), Gaps = 14/251 (5%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + + FSPDG +FQVEYA +AV+ STA+GIR + VV GVEK ++KL +E + +++ Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKI 64 Query: 68 FNVDRHVGMAVA------GLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVH 121 +D HV MA A GL ADAR + + AR E + + + ++++ +A Sbjct: 65 CALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQ 124 Query: 122 AYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQ 181 YT + RPFG S ++ + + ++LY DPSG + + AIG++ + + +EK Sbjct: 125 KYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNY 184 Query: 182 MKEMTCRDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 240 ++ D E K+ I + + V+ +EL+ + R++ + +E E Y Sbjct: 185 TEDAIASD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYV 237 Query: 241 KESLKEEDESD 251 E KE++E++ Sbjct: 238 TEIEKEKEEAE 248 >gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] Length = 234 Score = 111 bits (278), Expect = 5e-25 Identities = 64/186 (34%), Positives = 100/186 (53%), Gaps = 3/186 (1%) Query: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66 GY S +TFSP G++ Q+EYA+ AV + ++GI+ +GVV EK S LY+E S + Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64 Query: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126 + + +H+G+ +G+ D R L AR+ A + + IP L RVA + YT Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124 Query: 127 SAVRPFGCSFMLGSYSVNDG-AQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEM 185 VRPFG S ++ + N+G L+ DPSG + + A+GK KT +EK +++ Sbjct: 125 GGVRPFGVSLLICGW--NEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDL 182 Query: 186 TCRDIV 191 D + Sbjct: 183 ELEDAI 188 >gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] Length = 261 Score = 111 bits (277), Expect = 7e-25 Identities = 76/258 (29%), Positives = 128/258 (49%), Gaps = 16/258 (6%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE-GSNKR 66 YD + FSP+GR++QVEYAM+A+ ++ T +GI DGV+ E+ + KL +E +++ Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126 ++ ++ + +VAG+ +DA L + R A + + IP + L + AYT + Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--E 184 RPFG S + + + G QLY DPSG +YG W AA + K K E Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGE 183 Query: 185 MTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIR 233 MT + + K++ D K A ++E++ + NG+ +++ K Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEE 242 Query: 234 EEAEKYAKESLKEEDESD 251 EEA+ ++ KE+ E D Sbjct: 243 EEAKAEREKKEKEQKEKD 260 >gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] Length = 261 Score = 111 bits (277), Expect = 7e-25 Identities = 76/258 (29%), Positives = 128/258 (49%), Gaps = 16/258 (6%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE-GSNKR 66 YD + FSP+GR++QVEYAM+A+ ++ T +GI DGV+ E+ + KL +E +++ Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126 ++ ++ + +VAG+ +DA L + R A + + IP + L + AYT + Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--E 184 RPFG S + + + G QLY DPSG +YG W AA + K K E Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGE 183 Query: 185 MTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIR 233 MT + + K++ D K A ++E++ + NG+ +++ K Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEE 242 Query: 234 EEAEKYAKESLKEEDESD 251 EEA+ ++ KE+ E D Sbjct: 243 EEAKAEREKKEKEQKEKD 260 >gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] Length = 263 Score = 97.1 bits (240), Expect = 1e-20 Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 3/180 (1%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + +SP GR+ Q+EYAM+AV+ S +G++ K V K S+L K++ Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 63 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 +VD H+G+++AGL ADAR L + R+E + R F +P+ L + T Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 123 Query: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 187 RP+G ++ Y + G ++ PS + +IG Q+A+T +E+ + M C Sbjct: 124 GRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 182 >gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] Length = 269 Score = 97.1 bits (240), Expect = 1e-20 Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 3/180 (1%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + +SP GR+ Q+EYAM+AV+ S +G++ K V K S+L K++ Sbjct: 12 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 69 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 +VD H+G+++AGL ADAR L + R+E + R F +P+ L + T Sbjct: 70 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 129 Query: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 187 RP+G ++ Y + G ++ PS + +IG Q+A+T +E+ + M C Sbjct: 130 GRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 188 >gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] Length = 212 Score = 80.9 bits (198), Expect = 1e-15 Identities = 64/245 (26%), Positives = 111/245 (45%), Gaps = 46/245 (18%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + + FSPDG +FQVEYA +AV+ STA+GIR Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR-------------------------- 38 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 GL ADAR + + AR E + + + ++++ +A YT + Sbjct: 39 ------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86 Query: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 187 RPFG S ++ + + ++LY DPSG + + AIG++ + + +EK ++ Sbjct: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146 Query: 188 RDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 246 D E K+ I + + V+ +EL+ + R++ + +E E Y E KE Sbjct: 147 SD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYVTEIEKE 199 Query: 247 EDESD 251 ++E++ Sbjct: 200 KEEAE 204 >gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] Length = 130 Score = 76.6 bits (187), Expect = 2e-14 Identities = 39/109 (35%), Positives = 62/109 (56%), Gaps = 2/109 (1%) Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 YD + +SP GR+ Q+EYAM+AV+ S +G++ K V K S+L K++ Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 63 Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRV 116 +VD H+G+++AGL ADAR L + R+E + R F +P+ L + Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLI 112 >gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] Length = 190 Score = 63.2 bits (152), Expect = 2e-10 Identities = 52/188 (27%), Positives = 83/188 (44%), Gaps = 15/188 (7%) Query: 77 AVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSF 136 +VAG+ +DA L + R A + + IP + L + AYT + RPFG S Sbjct: 4 SVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 63 Query: 137 MLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--EMTCRDIVKEV 194 + + + G QLY DPSG +YG W AA + K K EMT + + Sbjct: 64 LYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALA 122 Query: 195 AKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIREEAEKYAKES 243 K++ D K A ++E++ + NG+ +++ K EEA+ ++ Sbjct: 123 IKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKK 181 Query: 244 LKEEDESD 251 KE+ E D Sbjct: 182 EKEQKEKD 189 >gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] Length = 272 Score = 60.1 bits (144), Expect = 2e-09 Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%) Query: 6 TGYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN 64 TG+D FSP +++QV+YA KA+ + T++ +R KD V K+V KL + S Sbjct: 91 TGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLD--SR 148 Query: 65 KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSN 102 LF + ++ G + G+ AD+RS A+ +A+N + N Sbjct: 149 THLFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYN 186 >gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] Length = 272 Score = 60.1 bits (144), Expect = 2e-09 Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%) Query: 6 TGYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN 64 TG+D FSP +++QV+YA KA+ + T++ +R KD V K+V KL + S Sbjct: 91 TGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLD--SR 148 Query: 65 KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSN 102 LF + ++ G + G+ AD+RS A+ +A+N + N Sbjct: 149 THLFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYN 186 >gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] Length = 272 Score = 60.1 bits (144), Expect = 2e-09 Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%) Query: 6 TGYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN 64 TG+D FSP +++QV+YA KA+ + T++ +R KD V K+V KL + S Sbjct: 91 TGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLD--SR 148 Query: 65 KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSN 102 LF + ++ G + G+ AD+RS A+ +A+N + N Sbjct: 149 THLFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYN 186 >gi|4504211 guanylate cyclase 1, soluble, alpha 2 [Homo sapiens] Length = 732 Score = 33.1 bits (74), Expect = 0.24 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Query: 9 DLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLF 68 +LS +PDGR Q+ + + + +G+R +FG + L+ +E GS+ R Sbjct: 598 ELSEEVLTPDGRPIQMRIGIHSGSVLAGVVGVRMPRYCLFG-NNVTLASKFESGSHPRRI 656 Query: 69 NV 70 NV Sbjct: 657 NV 658 >gi|212276078 leucine rich repeat (in FLII) interacting protein 1 isoform 1 [Homo sapiens] Length = 640 Score = 30.4 bits (67), Expect = 1.6 Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 20/85 (23%) Query: 169 ARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIV 228 A++AA+ E +++MKE+ + K IY +V+ K + L+ W G++ Sbjct: 39 AKRAARAEAREIRMKEL------ERQQKEIY----QVQKKYYGLDTKW-GDI-------- 79 Query: 229 PKDIREEAEKYAKESLKEEDESDDD 253 + E++E+Y++ S + SD+D Sbjct: 80 -EQWMEDSERYSRRSRRNTSASDED 103 >gi|50428925 cytoskeleton associated protein 1 [Homo sapiens] Length = 244 Score = 30.4 bits (67), Expect = 1.6 Identities = 12/24 (50%), Positives = 18/24 (75%) Query: 137 MLGSYSVNDGAQLYMIDPSGVSYG 160 +LGSY V+DG ++++ID SG G Sbjct: 73 LLGSYPVDDGCRIHVIDHSGARLG 96 >gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] Length = 1312 Score = 30.0 bits (66), Expect = 2.0 Identities = 13/21 (61%), Positives = 16/21 (76%) Query: 234 EEAEKYAKESLKEEDESDDDN 254 EEAE+ +E +EEDE DDDN Sbjct: 540 EEAEEEEEEEEEEEDEDDDDN 560 >gi|115529463 protein kinase D1 [Homo sapiens] Length = 912 Score = 28.5 bits (62), Expect = 5.9 Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 81 LLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSF 136 LL + S + I RE+ SN +S G I L + H + ++S RP C + Sbjct: 231 LLQKSPSESFIGREKRSNSQSYIGRPIHLDKILMSKVKVPHTFVIHSYTRPTVCQY 286 >gi|55749742 HEAT repeat containing 5B [Homo sapiens] Length = 2071 Score = 28.5 bits (62), Expect = 5.9 Identities = 11/27 (40%), Positives = 18/27 (66%) Query: 227 IVPKDIREEAEKYAKESLKEEDESDDD 253 +V +I++EAE K ++K D+ DDD Sbjct: 1431 VVAMNIKKEAESKPKRAIKNTDDDDDD 1457 >gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sapiens] Length = 1954 Score = 28.5 bits (62), Expect = 5.9 Identities = 11/25 (44%), Positives = 18/25 (72%) Query: 230 KDIREEAEKYAKESLKEEDESDDDN 254 K ++++ EK AK K+EDE D+D+ Sbjct: 101 KKLKDKKEKKAKRKKKDEDEDDNDD 125 >gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] Length = 1317 Score = 28.5 bits (62), Expect = 5.9 Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 13/80 (16%) Query: 170 RQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVP 229 +++ K E+E++Q + T R + V I + +K ++F +E Sbjct: 623 QKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKL------------- 669 Query: 230 KDIREEAEKYAKESLKEEDE 249 KD+ E EK+ +E L+E+ E Sbjct: 670 KDLLAEKEKFEEERLREQQE 689 >gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] Length = 679 Score = 28.1 bits (61), Expect = 7.8 Identities = 17/56 (30%), Positives = 30/56 (53%) Query: 200 IVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM 255 IVH KDK E V + + G + +++ + AEKYA+E ++++ + NM Sbjct: 529 IVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNM 584 >gi|23308729 zinc finger protein 268 [Homo sapiens] Length = 947 Score = 28.1 bits (61), Expect = 7.8 Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 8/120 (6%) Query: 125 LYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCA-IGKARQAAKTEIEKLQM- 182 +++ V+P+GCS ++S+ +QL + S +GC+ GKA ++ I ++ Sbjct: 661 VHTGVKPYGCSQCAKTFSLK--SQLIVHQRSHTGVKPYGCSECGKAFRSKSYLIIHMRTH 718 Query: 183 ---KEMTCRDIVKEVA-KIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEK 238 K CR+ K + IVH + E S G+ N + +++ EK Sbjct: 719 TGEKPHECRECGKSFSFNSQLIVHQRIHTGENPYECSECGKAFNRKDQLISHQRTHAGEK 778 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 28.1 bits (61), Expect = 7.8 Identities = 21/83 (25%), Positives = 43/83 (51%), Gaps = 19/83 (22%) Query: 169 ARQAAKTEIEKLQM--KEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHE 226 A++ KT I+K + KE +++ KE+ K +E K+ E+ + E Sbjct: 661 AKKEDKTPIKKEEKPKKEEVKKEVKKEIKK------EEKKEPKKEV-----------KKE 703 Query: 227 IVPKDIREEAEKYAKESLKEEDE 249 PK++++E +K K+ +K+E++ Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEK 726 >gi|157671915 guanylate binding protein family, member 6 [Homo sapiens] Length = 633 Score = 28.1 bits (61), Expect = 7.8 Identities = 27/122 (22%), Positives = 48/122 (39%), Gaps = 9/122 (7%) Query: 135 SFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEV 194 S GS+SV G +LYM + YW + + AK ++ +M + + + Sbjct: 420 SISAGSFSVPGGHKLYMETKERIEQDYW--QVPRKGVKAKEVFQRFLESQMVIEESILQS 477 Query: 195 AKII-----YIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA--KESLKEE 247 K + + D K +A E E + + + + + + E A KE L+ E Sbjct: 478 DKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQME 537 Query: 248 DE 249 E Sbjct: 538 RE 539 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,544,727 Number of Sequences: 37866 Number of extensions: 333861 Number of successful extensions: 1496 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 1447 Number of HSP's gapped (non-prelim): 39 length of query: 255 length of database: 18,247,518 effective HSP length: 100 effective length of query: 155 effective length of database: 14,460,918 effective search space: 2241442290 effective search space used: 2241442290 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.