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Search of human proteins with 13128862
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13128862 histone deacetylase 3 [Homo sapiens]
(428 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13128862 histone deacetylase 3 [Homo sapiens] 904 0.0
gi|13128860 histone deacetylase 1 [Homo sapiens] 552 e-157
gi|116284376 histone deacetylase 2 [Homo sapiens] 549 e-156
gi|8923769 histone deacetylase 8 [Homo sapiens] 313 2e-85
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] 90 4e-18
gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens] 90 4e-18
gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens] 90 4e-18
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 89 6e-18
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 89 6e-18
gi|153085395 histone deacetylase 4 [Homo sapiens] 87 4e-17
gi|148539870 histone deacetylase 7 isoform d [Homo sapiens] 86 6e-17
gi|169234807 histone deacetylase 7 isoform a [Homo sapiens] 86 6e-17
gi|13128864 histone deacetylase 6 [Homo sapiens] 83 4e-16
gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens] 77 4e-14
gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens] 68 2e-11
gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens] 68 2e-11
gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens] 66 5e-11
gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens] 66 7e-11
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 34 0.29
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 34 0.29
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 34 0.29
gi|239757046 PREDICTED: similar to hCG1790759 [Homo sapiens] 32 1.4
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso... 31 2.5
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso... 31 2.5
gi|187960042 selectin E precursor [Homo sapiens] 30 4.2
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 30 4.2
gi|4505999 protein phosphatase 1G [Homo sapiens] 30 4.2
gi|29826282 protein phosphatase 1G [Homo sapiens] 30 4.2
gi|83716024 kinesin family member 21B [Homo sapiens] 29 7.2
gi|23111023 sorting nexin 10 [Homo sapiens] 29 9.4
>gi|13128862 histone deacetylase 3 [Homo sapiens]
Length = 428
Score = 904 bits (2337), Expect = 0.0
Identities = 428/428 (100%), Positives = 428/428 (100%)
Query: 1 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR 60
MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
Sbjct: 1 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR 60
Query: 61 FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN 120
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
Sbjct: 61 FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN 120
Query: 121 KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA 180
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
Sbjct: 121 KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA 180
Query: 181 FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI 240
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
Sbjct: 181 FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI 240
Query: 241 NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV 300
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
Sbjct: 241 NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV 300
Query: 301 RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ 360
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
Sbjct: 301 RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ 360
Query: 361 TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN 420
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
Sbjct: 361 TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN 420
Query: 421 DKESDVEI 428
DKESDVEI
Sbjct: 421 DKESDVEI 428
>gi|13128860 histone deacetylase 1 [Homo sapiens]
Length = 482
Score = 552 bits (1422), Expect = e-157
Identities = 250/425 (58%), Positives = 332/425 (78%), Gaps = 11/425 (2%)
Query: 3 KTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFH 62
+ V Y+YD DVGN++YG GHPMKPHR+ +TH+L+L+YGLY+KM +++P++A+ +M ++H
Sbjct: 9 RKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYH 68
Query: 63 SEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKI 122
S+DYI FL+ + P NM ++K + FNVG+DCPVF GLFEFC TG S+ A +LN +
Sbjct: 69 SDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQ 128
Query: 123 CDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFY 182
DIA+NWAGGLHHAKK EASGFCYVNDIV+ ILELLKYH RVLYIDIDIHHGDGV+EAFY
Sbjct: 129 TDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFY 188
Query: 183 LTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQ 242
TDRVMTVSFHKYG Y FPGTGD+ ++GA G+YY +N PLRDGIDD+SY+ +F+PV+++
Sbjct: 189 TTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSK 247
Query: 243 VVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRN 302
V++ +QP+ +VLQCG+DSL DRLGCFNL+I+GH +CVE+VKSFN+P+L+LGGGGYT+RN
Sbjct: 248 VMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRN 307
Query: 303 VARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTI 362
VARCWTYET++ ++ I ELPY++YFEYF PDF LH S + NQN+ +YL++I+Q +
Sbjct: 308 VARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS-NMTNQNTNEYLEKIKQRL 366
Query: 363 FENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYS------RPEAPNEFYDG 416
FENL+ML HAP VQ+ +P D + + DE +E P++ S R EF D
Sbjct: 367 FENLRMLPHAPGVQMQAIPEDAIPEESGDE---DEDDPDKRISICSSDKRIACEEEFSDS 423
Query: 417 DHDND 421
+ + +
Sbjct: 424 EEEGE 428
>gi|116284376 histone deacetylase 2 [Homo sapiens]
Length = 582
Score = 549 bits (1415), Expect = e-156
Identities = 250/425 (58%), Positives = 332/425 (78%), Gaps = 11/425 (2%)
Query: 3 KTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFH 62
K V Y+YD D+GN++YG GHPMKPHR+ +TH+L+L+YGLY+KM +++P++A+ +M ++H
Sbjct: 104 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYH 163
Query: 63 SEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKI 122
S++YI FL+ + P NM ++K + FNVG+DCPVF GLFEFC TG S+ GA +LN +
Sbjct: 164 SDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQ 223
Query: 123 CDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFY 182
D+A+NWAGGLHHAKK EASGFCYVNDIV+ ILELLKYH RVLYIDIDIHHGDGV+EAFY
Sbjct: 224 TDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFY 283
Query: 183 LTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQ 242
TDRVMTVSFHKYG Y FPGTGD+ ++GA G+YY +N P+RDGIDD+SY +F+P+I++
Sbjct: 284 TTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISK 342
Query: 243 VVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRN 302
V++ YQP+ +VLQCGADSL DRLGCFNL+++GH +CVE VK+FN+PLL+LGGGGYT+RN
Sbjct: 343 VMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRN 402
Query: 303 VARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTI 362
VARCWTYET++ ++ I ELPY++YFEYF PDF LH S + NQN+ +Y+++I+Q +
Sbjct: 403 VARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPS-NMTNQNTPEYMEKIKQRL 461
Query: 363 FENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYS------RPEAPNEFYDG 416
FENL+ML HAP VQ+ +P D + D DE D E+ P++ S R EF D
Sbjct: 462 FENLRMLPHAPGVQMQAIPEDAVHEDSGDE-DGED--PDKRISIRASDKRIACDEEFSDS 518
Query: 417 DHDND 421
+ + +
Sbjct: 519 EDEGE 523
>gi|8923769 histone deacetylase 8 [Homo sapiens]
Length = 377
Score = 313 bits (802), Expect = 2e-85
Identities = 148/342 (43%), Positives = 220/342 (64%), Gaps = 2/342 (0%)
Query: 26 PHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSL 85
P R ++ HSL+ Y L+K+M + KP AS +M FH++ Y+ LQ+VS S+
Sbjct: 35 PKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSI 94
Query: 86 NAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFC 145
+ +G DCP G+F++ + GA++ A L + +C +AINW+GG HHAKK EASGFC
Sbjct: 95 E-YGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFC 153
Query: 146 YVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGD 205
Y+ND V+GIL L + R+LY+D+D+HHGDGV++AF T +VMTVS HK+ FFPGTGD
Sbjct: 154 YLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGD 213
Query: 206 MYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDR 265
+ +VG GRYY +NVP++DGI D+ Y + + V+ +V + P +VLQ GAD++ D
Sbjct: 214 VSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDP 273
Query: 266 LGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPY 325
+ FN++ G G+C++Y+ + + L+LGGGGY + N ARCWTY T +++ + +S E+P
Sbjct: 274 MCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPD 333
Query: 326 SEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLK 367
E+F + PD+ L S R ++N + QI I NLK
Sbjct: 334 HEFFTAYGPDYVLEITPSCR-PDRNEPHRIQQILNYIKGNLK 374
>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
Length = 1069
Score = 89.7 bits (221), Expect = 4e-18
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 9/136 (6%)
Query: 134 HHAKKFEASGFCYVNDIVIGILELLKYH--PRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ A GFC+ N + I L ++L +D+D+HHG+G Q+AFY ++ +S
Sbjct: 785 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 844
Query: 192 FHKY--GNYFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVD 245
H+Y GN FFPG+G EVG G Y +N+ G+D D Y F+ ++ V
Sbjct: 845 LHRYDEGN-FFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAK 903
Query: 246 FYQPTCIVLQCGADSL 261
+ P +++ G D+L
Sbjct: 904 EFDPDMVLVSAGFDAL 919
>gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]
Length = 1011
Score = 89.7 bits (221), Expect = 4e-18
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 9/136 (6%)
Query: 134 HHAKKFEASGFCYVNDIVIGILELLKYH--PRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ A GFC+ N + I L ++L +D+D+HHG+G Q+AFY ++ +S
Sbjct: 782 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 841
Query: 192 FHKY--GNYFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVD 245
H+Y GN FFPG+G EVG G Y +N+ G+D D Y F+ ++ V
Sbjct: 842 LHRYDEGN-FFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAK 900
Query: 246 FYQPTCIVLQCGADSL 261
+ P +++ G D+L
Sbjct: 901 EFDPDMVLVSAGFDAL 916
>gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]
Length = 1066
Score = 89.7 bits (221), Expect = 4e-18
Identities = 47/136 (34%), Positives = 74/136 (54%), Gaps = 9/136 (6%)
Query: 134 HHAKKFEASGFCYVNDIVIGILELLKYH--PRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ A GFC+ N + I L ++L +D+D+HHG+G Q+AFY ++ +S
Sbjct: 782 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 841
Query: 192 FHKY--GNYFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVD 245
H+Y GN FFPG+G EVG G Y +N+ G+D D Y F+ ++ V
Sbjct: 842 LHRYDEGN-FFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAK 900
Query: 246 FYQPTCIVLQCGADSL 261
+ P +++ G D+L
Sbjct: 901 EFDPDMVLVSAGFDAL 916
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 89.4 bits (220), Expect = 6e-18
Identities = 57/172 (33%), Positives = 87/172 (50%), Gaps = 16/172 (9%)
Query: 134 HHAKKFEASGFCYVNDIVIG--ILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ A GFC+ N + I +L+ +VL +D DIHHG+G Q+AFY V+ +S
Sbjct: 833 HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYIS 892
Query: 192 FHKYGN-YFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVDF 246
H+Y N FFPG+G EVG G Y +NV G+D D Y F+ V+ +
Sbjct: 893 LHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHE 952
Query: 247 YQPTCIVLQCGADSL--GCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGG 296
+ P +++ G D++ LG ++++ R G L+ L GG
Sbjct: 953 FSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTR-------QLMTLAGG 997
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 89.4 bits (220), Expect = 6e-18
Identities = 57/172 (33%), Positives = 87/172 (50%), Gaps = 16/172 (9%)
Query: 134 HHAKKFEASGFCYVNDIVIG--ILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ A GFC+ N + I +L+ +VL +D DIHHG+G Q+AFY V+ +S
Sbjct: 832 HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYIS 891
Query: 192 FHKYGN-YFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVDF 246
H+Y N FFPG+G EVG G Y +NV G+D D Y F+ V+ +
Sbjct: 892 LHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHE 951
Query: 247 YQPTCIVLQCGADSL--GCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGG 296
+ P +++ G D++ LG ++++ R G L+ L GG
Sbjct: 952 FSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTR-------QLMTLAGG 996
>gi|153085395 histone deacetylase 4 [Homo sapiens]
Length = 1084
Score = 86.7 bits (213), Expect = 4e-17
Identities = 52/154 (33%), Positives = 82/154 (53%), Gaps = 11/154 (7%)
Query: 134 HHAKKFEASGFCYVNDIVIG--ILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ GFCY N + + +L+ ++L +D D+HHG+G Q+AFY V+ +S
Sbjct: 802 HHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMS 861
Query: 192 FHKY--GNYFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVD 245
H+Y GN FFPG+G EVG G + +N+ G+D D Y F+ V+ +
Sbjct: 862 LHRYDDGN-FFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIAS 920
Query: 246 FYQPTCIVLQCGADSL--GCDRLGCFNLSIRGHG 277
+ P +++ G D++ LG +NLS R G
Sbjct: 921 EFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFG 954
>gi|148539870 histone deacetylase 7 isoform d [Homo sapiens]
Length = 954
Score = 85.9 bits (211), Expect = 6e-17
Identities = 47/135 (34%), Positives = 74/135 (54%), Gaps = 9/135 (6%)
Query: 134 HHAKKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA A GFC+ N + I +L + ++L +D D+HHG+G Q+ FY V+ +S
Sbjct: 671 HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYIS 730
Query: 192 FHKY--GNYFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVD 245
H++ GN FFPG+G + EVGA SG + +NV G+D D Y F+ V+ +
Sbjct: 731 LHRHDDGN-FFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAR 789
Query: 246 FYQPTCIVLQCGADS 260
+ P +++ G D+
Sbjct: 790 EFSPDLVLVSAGFDA 804
>gi|169234807 histone deacetylase 7 isoform a [Homo sapiens]
Length = 991
Score = 85.9 bits (211), Expect = 6e-17
Identities = 47/135 (34%), Positives = 74/135 (54%), Gaps = 9/135 (6%)
Query: 134 HHAKKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA A GFC+ N + I +L + ++L +D D+HHG+G Q+ FY V+ +S
Sbjct: 708 HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYIS 767
Query: 192 FHKY--GNYFFPGTGDMYEVGAESGRYYCLNVPLRDGID----DQSYKHLFQPVINQVVD 245
H++ GN FFPG+G + EVGA SG + +NV G+D D Y F+ V+ +
Sbjct: 768 LHRHDDGN-FFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAR 826
Query: 246 FYQPTCIVLQCGADS 260
+ P +++ G D+
Sbjct: 827 EFSPDLVLVSAGFDA 841
>gi|13128864 histone deacetylase 6 [Homo sapiens]
Length = 1215
Score = 83.2 bits (204), Expect = 4e-16
Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 12/292 (4%)
Query: 22 HPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGF 81
HP P R+ + GL + + P A++ ++ HS +Y+ L+ +
Sbjct: 500 HPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTREL 559
Query: 82 TKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQ-LNNKICDIAINWAGGLHHAKKFE 140
+ + F D + P F TGA+ + L+ ++ + A HHA++
Sbjct: 560 HRESSNF---DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDA 616
Query: 141 ASGFCYVNDIVIGI--LELLKYHP-RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN 197
A GFC+ N + + + + H R+L +D D+HHG+G Q F V+ VS H+Y +
Sbjct: 617 ACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDH 676
Query: 198 -YFFP--GTGDMYEVGAESGRYYCLNVPLR-DGIDDQSYKHLFQPVINQVVDFYQPTCIV 253
FFP G ++G +G + +NV + D Y + ++ + + P ++
Sbjct: 677 GTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVL 736
Query: 254 LQCGADSLGCDRLGCFNLSIRGHGECVEYVKSF-NIPLLVLGGGGYTVRNVA 304
+ G D+ D LG +S G+ + + ++++ GGY + +++
Sbjct: 737 VSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSIS 788
Score = 78.2 bits (191), Expect = 1e-14
Identities = 74/311 (23%), Positives = 124/311 (39%), Gaps = 25/311 (8%)
Query: 10 DPDVGNFH--YGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67
D + FH + P P RL ++ GL + + F+ A + ++ HS +YI
Sbjct: 91 DEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYI 150
Query: 68 DFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAI 127
D ++ T+ +N + + ++ + Y+ A L + L +
Sbjct: 151 DLMET---------TQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGA 201
Query: 128 NWAGGL-------HHAKKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQ 178
G+ HHA+ G+C N + + + H RVL +D D+HHG G Q
Sbjct: 202 EIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQ 261
Query: 179 EAFYLTDRVMTVSFHKY-GNYFFP--GTGDMYEVGAESGRYYCLNVPLRD-GIDDQSYKH 234
F V+ S H+Y F+P + G G+ Y +NVP G+ D Y
Sbjct: 262 FTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIA 321
Query: 235 LFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLG 294
F V+ V +QP +++ G D+L D G + G + + L+L
Sbjct: 322 AFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILS 381
Query: 295 -GGGYTVRNVA 304
GGY +R +A
Sbjct: 382 LEGGYNLRALA 392
>gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]
Length = 669
Score = 76.6 bits (187), Expect = 4e-14
Identities = 81/313 (25%), Positives = 134/313 (42%), Gaps = 41/313 (13%)
Query: 25 KPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKS 84
+P RL + GL ++ + +AS+ ++ HS +Y+ ++ T + G +
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRE---TQVLG-KEE 82
Query: 85 LNAFNVGDDCPVF-PGLFEFCSRYTGASLQ-------GATQLNNKICDIAINWAGGLHHA 136
L A + D F P F GA LQ GA Q +A+ G HH
Sbjct: 83 LQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNG-----LALVRPPG-HHG 136
Query: 137 KKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHK 194
++ A+GFC N++ I + H R+L +D D+HHG G+Q F V+ S+H+
Sbjct: 137 QRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHR 196
Query: 195 Y--GNYF-FPGTGDMYEVGAESGRYYCLNVPLRD-GIDDQSYKHLFQPVINQVVDFYQPT 250
Y G ++ F D VG G + +N+P G+ + Y F ++ + + P
Sbjct: 197 YEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPE 256
Query: 251 CIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGG--------GGYTVRN 302
+++ G DS D G ++ EC ++ L VL G GGY + +
Sbjct: 257 LVLVSAGFDSAIGDPEG----QMQATPECFAHLTQL---LQVLAGGRVCAVLEGGYHLES 309
Query: 303 VAR--CWTYETSL 313
+A C T +T L
Sbjct: 310 LAESVCMTVQTLL 322
>gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens]
Length = 347
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/183 (30%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Query: 126 AINWAGGLHHAKKFEASGFCYVNDIVIGI---LELLKYHPRVLYIDIDIHHGDGVQEAFY 182
AIN GG HH GFC DI + I E ++ R ID+D H G+G + F
Sbjct: 134 AINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFM 193
Query: 183 LTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQ 242
RV + Y + +P GD + A + V L G +D Y + I +
Sbjct: 194 DDKRVYIMDV--YNRHIYP--GDRFAKQAIRRK-----VELEWGTEDDEYLDKVERNIKK 244
Query: 243 VVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRG---HGECV-EYVKSFNIPLLVLGGGGY 298
+ + P +V G D L DRLG ++S G E V V+ +P+L++ GGY
Sbjct: 245 SLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGY 304
Query: 299 TVR 301
R
Sbjct: 305 QKR 307
>gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens]
Length = 296
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/183 (30%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Query: 126 AINWAGGLHHAKKFEASGFCYVNDIVIGI---LELLKYHPRVLYIDIDIHHGDGVQEAFY 182
AIN GG HH GFC DI + I E ++ R ID+D H G+G + F
Sbjct: 83 AINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFM 142
Query: 183 LTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQ 242
RV + Y + +P GD + A + V L G +D Y + I +
Sbjct: 143 DDKRVYIMDV--YNRHIYP--GDRFAKQAIRRK-----VELEWGTEDDEYLDKVERNIKK 193
Query: 243 VVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRG---HGECV-EYVKSFNIPLLVLGGGGY 298
+ + P +V G D L DRLG ++S G E V V+ +P+L++ GGY
Sbjct: 194 SLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGY 253
Query: 299 TVR 301
R
Sbjct: 254 QKR 256
>gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]
Length = 879
Score = 66.2 bits (160), Expect = 5e-11
Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 5/80 (6%)
Query: 134 HHAKKFEASGFCYVNDIVIGILELLKYH--PRVLYIDIDIHHGDGVQEAFYLTDRVMTVS 191
HHA++ A GFC+ N + I L ++L +D+D+HHG+G Q+AFY ++ +S
Sbjct: 782 HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHHGNGTQQAFYADPSILYIS 841
Query: 192 FHKY--GNYFFPGTGDMYEV 209
H+Y GN FFPG+G EV
Sbjct: 842 LHRYDEGN-FFPGSGAPNEV 860
>gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]
Length = 649
Score = 65.9 bits (159), Expect = 7e-11
Identities = 58/211 (27%), Positives = 94/211 (44%), Gaps = 23/211 (10%)
Query: 25 KPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKS 84
+P RL + GL ++ + +AS+ ++ HS +Y+ ++ T + G +
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRE---TQVLG-KEE 82
Query: 85 LNAFNVGDDCPVF-PGLFEFCSRYTGASLQ-------GATQLNNKICDIAINWAGGLHHA 136
L A + D F P F GA LQ GA Q +A+ G HH
Sbjct: 83 LQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNG-----LALVRPPG-HHG 136
Query: 137 KKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHK 194
++ A+GFC N++ I + H R+L +D D+HHG G+Q F V+ S+H+
Sbjct: 137 QRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHR 196
Query: 195 Y--GNYF-FPGTGDMYEVGAESGRYYCLNVP 222
Y G ++ F D VG G + +N+P
Sbjct: 197 YEHGRFWPFLRESDADAVGRGQGLGFTVNLP 227
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 33.9 bits (76), Expect = 0.29
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 355 LDQIRQTIFENLKMLNHAPSVQIHDVPA------DLLTYDRTDEADAE-ERGPEENYSRP 407
L+ R++IFE L+ + + D A D D DE + E E GP E Y
Sbjct: 128 LEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEE 187
Query: 408 EAPNEFYDGDHDNDKE 423
E E D D D D++
Sbjct: 188 EEEEEEEDEDEDEDED 203
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 33.9 bits (76), Expect = 0.29
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 355 LDQIRQTIFENLKMLNHAPSVQIHDVPA------DLLTYDRTDEADAE-ERGPEENYSRP 407
L+ R++IFE L+ + + D A D D DE + E E GP E Y
Sbjct: 87 LEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEE 146
Query: 408 EAPNEFYDGDHDNDKE 423
E E D D D D++
Sbjct: 147 EEEEEEEDEDEDEDED 162
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 33.9 bits (76), Expect = 0.29
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 7/76 (9%)
Query: 355 LDQIRQTIFENLKMLNHAPSVQIHDVPA------DLLTYDRTDEADAE-ERGPEENYSRP 407
L+ R++IFE L+ + + D A D D DE + E E GP E Y
Sbjct: 80 LEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEE 139
Query: 408 EAPNEFYDGDHDNDKE 423
E E D D D D++
Sbjct: 140 EEEEEEEDEDEDEDED 155
>gi|239757046 PREDICTED: similar to hCG1790759 [Homo sapiens]
Length = 737
Score = 31.6 bits (70), Expect = 1.4
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Query: 11 PDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMI 46
P+V + HYG HPM THS V+H G + K I
Sbjct: 641 PEVPDDHYGTAHPM-------THSGVVHLGTHMKHI 669
>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
isoform hUpf3p [Homo sapiens]
Length = 476
Score = 30.8 bits (68), Expect = 2.5
Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 3/35 (8%)
Query: 314 LVEEAISEEL---PYSEYFEYFAPDFTLHPDVSTR 345
L +E + E+L P +YFE+FA D +L+P + +R
Sbjct: 79 LTKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSR 113
>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
isoform hUpf3pdelta [Homo sapiens]
Length = 443
Score = 30.8 bits (68), Expect = 2.5
Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 3/35 (8%)
Query: 314 LVEEAISEEL---PYSEYFEYFAPDFTLHPDVSTR 345
L +E + E+L P +YFE+FA D +L+P + +R
Sbjct: 79 LTKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSR 113
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 30.0 bits (66), Expect = 4.2
Identities = 11/24 (45%), Positives = 14/24 (58%)
Query: 263 CDRLGCFNLSIRGHGECVEYVKSF 286
C C N S GHGECVE + ++
Sbjct: 138 CYTAACTNTSCSGHGECVETINNY 161
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 30.0 bits (66), Expect = 4.2
Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 355 LDQIRQTIFENLKMLNHAPSVQIHD--VPADLLTYDRTDEADAEERGP-----------E 401
L+ R+++F+ L L + D P D DE + +E G E
Sbjct: 128 LNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEE 187
Query: 402 ENYSRPEAPNEFYDGDHDNDKESDVE 427
E + + +E +GD D+D+ S+ E
Sbjct: 188 EEFDEEDDEDEDVEGDEDDDEVSEEE 213
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 30.0 bits (66), Expect = 4.2
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
Query: 388 DRTDEADAEERGPEE------NYSRPEAPNEFYDGDHDNDKESDVE 427
D +DEA+ EE EE YS EA NE + D + +E D E
Sbjct: 262 DESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEE 307
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 30.0 bits (66), Expect = 4.2
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
Query: 388 DRTDEADAEERGPEE------NYSRPEAPNEFYDGDHDNDKESDVE 427
D +DEA+ EE EE YS EA NE + D + +E D E
Sbjct: 262 DESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEE 307
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 29.3 bits (64), Expect = 7.2
Identities = 34/130 (26%), Positives = 52/130 (40%), Gaps = 17/130 (13%)
Query: 311 TSLLVEEAISEEL-----------PYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIR 359
T LL EA++E L PYS AP F P S ++ R+ +
Sbjct: 490 TKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLE 549
Query: 360 QTIFENLKMLNHAPSVQIHDVPADLL--TYDRTDEADAEERGPEENYSRPEAPNEFYDGD 417
+ + ++ +P + A L + TDE +AE EE R E+ E +G
Sbjct: 550 RLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAE----EEEEERDESGCEEEEGR 605
Query: 418 HDNDKESDVE 427
D D++S E
Sbjct: 606 EDEDEDSGSE 615
>gi|23111023 sorting nexin 10 [Homo sapiens]
Length = 201
Score = 28.9 bits (63), Expect = 9.4
Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 9/88 (10%)
Query: 348 NQNSRQYLDQIRQTIFENL-KMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSR 406
N N+RQ++DQ RQ + + L K+L +A + + L ++ +++ +A G + YS
Sbjct: 84 NMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSG-QTKYSV 142
Query: 407 PEAPNEFY-------DGDHDNDKESDVE 427
EA ++F + D + KE+D++
Sbjct: 143 EEAIHKFALMNRRFPEEDEEGKKENDID 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.141 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,424,119
Number of Sequences: 37866
Number of extensions: 807345
Number of successful extensions: 1737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1668
Number of HSP's gapped (non-prelim): 38
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.