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Search of human proteins with 13128860
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13128860 histone deacetylase 1 [Homo sapiens]
(482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13128860 histone deacetylase 1 [Homo sapiens] 998 0.0
gi|116284376 histone deacetylase 2 [Homo sapiens] 871 0.0
gi|13128862 histone deacetylase 3 [Homo sapiens] 552 e-157
gi|8923769 histone deacetylase 8 [Homo sapiens] 322 6e-88
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] 110 3e-24
gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens] 110 3e-24
gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens] 109 6e-24
gi|148539870 histone deacetylase 7 isoform d [Homo sapiens] 108 1e-23
gi|169234807 histone deacetylase 7 isoform a [Homo sapiens] 108 1e-23
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 105 7e-23
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 105 7e-23
gi|153085395 histone deacetylase 4 [Homo sapiens] 104 2e-22
gi|13128864 histone deacetylase 6 [Homo sapiens] 102 1e-21
gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens] 96 9e-20
gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens] 79 1e-14
gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens] 77 3e-14
gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens] 75 1e-13
gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens] 75 1e-13
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 50 5e-06
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 48 2e-05
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 46 7e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 46 9e-05
gi|21735569 claspin [Homo sapiens] 45 1e-04
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 44 3e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 4e-04
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 44 4e-04
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 44 4e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 44 4e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens] 43 7e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 43 7e-04
>gi|13128860 histone deacetylase 1 [Homo sapiens]
Length = 482
Score = 998 bits (2580), Expect = 0.0
Identities = 482/482 (100%), Positives = 482/482 (100%)
Query: 1 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN 60
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN
Sbjct: 1 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN 60
Query: 61 AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS 120
AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS
Sbjct: 61 AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS 120
Query: 121 AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG 180
AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG
Sbjct: 121 AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG 180
Query: 181 DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI 240
DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
Sbjct: 181 DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI 240
Query: 241 FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG 300
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
Sbjct: 241 FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG 300
Query: 301 GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE 360
GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
Sbjct: 301 GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE 360
Query: 361 KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEF 420
KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEF
Sbjct: 361 KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEF 420
Query: 421 SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK 480
SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
Sbjct: 421 SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK 480
Query: 481 LA 482
LA
Sbjct: 481 LA 482
>gi|116284376 histone deacetylase 2 [Homo sapiens]
Length = 582
Score = 871 bits (2251), Expect = 0.0
Identities = 415/483 (85%), Positives = 454/483 (93%), Gaps = 5/483 (1%)
Query: 1 MAQTQGT-RRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA 59
MA +QG ++KVCYYYDGD+GNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
Sbjct: 95 MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA 154
Query: 60 NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA 119
AEEMTKYHSD+YIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA
Sbjct: 155 TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA 214
Query: 120 SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH 179
AVKLN+QQTD+AVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH
Sbjct: 215 GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH 274
Query: 180 GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEA 239
GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVN+P+RDGIDDESY
Sbjct: 275 GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ 334
Query: 240 IFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLG 299
IFKP++SKVMEM+QPSAVVLQCG+DSLSGDRLGCFNLT+KGHAKCVE VK+FNLP+LMLG
Sbjct: 335 IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG 394
Query: 300 GGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYL 359
GGGYTIRNVARCWTYETAVALD EIPNELPYNDYFEYFGPDFKLHISPSNMTNQNT EY+
Sbjct: 395 GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM 454
Query: 360 EKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEE 419
EKIKQRLFENLRMLPHAPGVQMQAIPEDA+ E+SGDED +DPDKRISI +SDKRIAC+EE
Sbjct: 455 EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE 514
Query: 420 FSDSEEEGEGGRKNSSNFKK-AKRVKTEDEKEKDPEEKKEVTEEEKTKE---EKPEAKGV 475
FSDSE+EGEGGR+N ++ KK AK+ + E++K++ ++K +V EE+K+K+ EK + KG
Sbjct: 515 FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGT 574
Query: 476 KEE 478
K E
Sbjct: 575 KSE 577
>gi|13128862 histone deacetylase 3 [Homo sapiens]
Length = 428
Score = 552 bits (1422), Expect = e-157
Identities = 250/425 (58%), Positives = 332/425 (78%), Gaps = 11/425 (2%)
Query: 9 RKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYH 68
+ V Y+YD DVGN++YG GHPMKPHR+ +TH+L+L+YGLY+KM +++P++A+ +M ++H
Sbjct: 3 KTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFH 62
Query: 69 SDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQ 128
S+DYI FL+ + P NM ++K + FNVG+DCPVF GLFEFC TG S+ A +LN +
Sbjct: 63 SEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKI 122
Query: 129 TDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFY 188
DIA+NWAGGLHHAKK EASGFCYVNDIV+ ILELLKYH RVLYIDIDIHHGDGV+EAFY
Sbjct: 123 CDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFY 182
Query: 189 TTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSK 247
TDRVMTVSFHKYG Y FPGTGD+ ++GA G+YY +N PLRDGIDD+SY+ +F+PV+++
Sbjct: 183 LTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQ 242
Query: 248 VMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRN 307
V++ +QP+ +VLQCG+DSL DRLGCFNL+I+GH +CVE+VKSFN+P+L+LGGGGYT+RN
Sbjct: 243 VVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRN 302
Query: 308 VARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS-NMTNQNTNEYLEKIKQRL 366
VARCWTYET++ ++ I ELPY++YFEYF PDF LH S + NQN+ +YL++I+Q +
Sbjct: 303 VARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTI 362
Query: 367 FENLRMLPHAPGVQMQAIPEDAIPEESGDE---DEDDPDKRISICSSDKRIACEEEFSDS 423
FENL+ML HAP VQ+ +P D + + DE +E P++ S R EF D
Sbjct: 363 FENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYS------RPEAPNEFYDG 416
Query: 424 EEEGE 428
+ + +
Sbjct: 417 DHDND 421
>gi|8923769 histone deacetylase 8 [Homo sapiens]
Length = 377
Score = 322 bits (824), Expect = 6e-88
Identities = 147/341 (43%), Positives = 227/341 (66%), Gaps = 2/341 (0%)
Query: 32 PHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQM 91
P R M H+L+ Y L+++M I +P A+ EEM +H+D Y++ L+ + + ++ +
Sbjct: 35 PKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSI 94
Query: 92 QRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFC 151
+ + +G DCP +G+F++ G ++ +A L +A+NW+GG HHAKK EASGFC
Sbjct: 95 E-YGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFC 153
Query: 152 YVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGE-YFPGTGD 210
Y+ND VL IL L + +R+LY+D+D+HHGDGVE+AF T +VMTVS HK+ +FPGTGD
Sbjct: 154 YLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGD 213
Query: 211 LRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDR 270
+ D+G GKG+YY+VN P++DGI DE Y I + V+ +V + F P AVVLQ G+D+++GD
Sbjct: 214 VSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDP 273
Query: 271 LGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPY 330
+ FN+T G KC++++ + L L+LGGGGY + N ARCWTY T V L + +E+P
Sbjct: 274 MCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPD 333
Query: 331 NDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLR 371
+++F +GPD+ L I+PS ++N +++I + NL+
Sbjct: 334 HEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLK 374
>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
Length = 1069
Score = 110 bits (275), Expect = 3e-24
Identities = 105/385 (27%), Positives = 170/385 (44%), Gaps = 63/385 (16%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E + KA+ EE+ HS+ + + N +
Sbjct: 657 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGT----NPLDG 712
Query: 88 SKQMQRFNVGEDCPVFDGLFEFCQLSTGG--------------------------SVASA 121
K R +G+D F F L GG +AS
Sbjct: 713 QKLDPRILLGDDSQKF-----FSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASK 767
Query: 122 VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHH 179
V + + AV G HHA++S A GFC+ N + + L ++L +D+D+HH
Sbjct: 768 VASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHH 826
Query: 180 GDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID---- 233
G+G ++AFY ++ +S H+Y G +FPG+G ++G G G+ Y +N G+D
Sbjct: 827 GNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMG 886
Query: 234 DESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDR--LGCFNLTIK--GH-AKCVEFV 288
D Y F+ ++ V + F P V++ G D+L G LG + +T K GH K + +
Sbjct: 887 DVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTL 946
Query: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
+ + + GG T A C E V + + NEL E D LH SP
Sbjct: 947 ADGRVVLALEGGHDLT----AICDASEACV--NALLGNEL------EPLAEDI-LHQSP- 992
Query: 349 NMTNQNTNEYLEKIKQRLFENLRML 373
NM + + + +I+ + ++++RM+
Sbjct: 993 NMNAVISLQKIIEIQSKYWKSVRMV 1017
>gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]
Length = 1066
Score = 110 bits (275), Expect = 3e-24
Identities = 105/385 (27%), Positives = 170/385 (44%), Gaps = 63/385 (16%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E + KA+ EE+ HS+ + + N +
Sbjct: 654 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGT----NPLDG 709
Query: 88 SKQMQRFNVGEDCPVFDGLFEFCQLSTGG--------------------------SVASA 121
K R +G+D F F L GG +AS
Sbjct: 710 QKLDPRILLGDDSQKF-----FSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASK 764
Query: 122 VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHH 179
V + + AV G HHA++S A GFC+ N + + L ++L +D+D+HH
Sbjct: 765 VASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHH 823
Query: 180 GDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID---- 233
G+G ++AFY ++ +S H+Y G +FPG+G ++G G G+ Y +N G+D
Sbjct: 824 GNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMG 883
Query: 234 DESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDR--LGCFNLTIK--GH-AKCVEFV 288
D Y F+ ++ V + F P V++ G D+L G LG + +T K GH K + +
Sbjct: 884 DVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTL 943
Query: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
+ + + GG T A C E V + + NEL E D LH SP
Sbjct: 944 ADGRVVLALEGGHDLT----AICDASEACV--NALLGNEL------EPLAEDI-LHQSP- 989
Query: 349 NMTNQNTNEYLEKIKQRLFENLRML 373
NM + + + +I+ + ++++RM+
Sbjct: 990 NMNAVISLQKIIEIQSKYWKSVRMV 1014
>gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]
Length = 1011
Score = 109 bits (272), Expect = 6e-24
Identities = 83/292 (28%), Positives = 130/292 (44%), Gaps = 48/292 (16%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E + KA+ EE+ HS+ + + N +
Sbjct: 654 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGT----NPLDG 709
Query: 88 SKQMQRFNVGEDCPVFDGLFEFCQLSTGG--------------------------SVASA 121
K R +G+D F F L GG +AS
Sbjct: 710 QKLDPRILLGDDSQKF-----FSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASK 764
Query: 122 VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHH 179
V + + AV G HHA++S A GFC+ N + + L ++L +D+D+HH
Sbjct: 765 VASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHH 823
Query: 180 GDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID---- 233
G+G ++AFY ++ +S H+Y G +FPG+G ++G G G+ Y +N G+D
Sbjct: 824 GNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMG 883
Query: 234 DESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDR--LGCFNLTIK--GH 281
D Y F+ ++ V + F P V++ G D+L G LG + +T K GH
Sbjct: 884 DVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGH 935
>gi|148539870 histone deacetylase 7 isoform d [Homo sapiens]
Length = 954
Score = 108 bits (270), Expect = 1e-23
Identities = 85/318 (26%), Positives = 138/318 (43%), Gaps = 61/318 (19%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKF-----LRSIRPD 82
HP RI+ + L GL + E R KA+ EE+ HS+ ++ L ++ D
Sbjct: 543 HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD 602
Query: 83 NMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGG-SVASAVKLNKQQTDIAVNWAGGL-- 139
N QR F L GG V + N+ + A WA G
Sbjct: 603 NGKLAGLLAQRM--------------FVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVT 648
Query: 140 ----------------------HHAKKSEASGFCYVNDIVLAILELLKYHQ--RVLYIDI 175
HHA S A GFC+ N + +A +L + + ++L +D
Sbjct: 649 DLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDW 708
Query: 176 DIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID 233
D+HHG+G ++ FY V+ +S H++ G +FPG+G + ++GAG G+ + VN G+D
Sbjct: 709 DVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLD 768
Query: 234 ----DESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGD--RLGCFNLTIKGHAKCVEF 287
D Y A F+ V+ + F P V++ G D+ G LG ++++ AKC +
Sbjct: 769 PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS----AKCFGY 824
Query: 288 VKSFNLPMLMLGGGGYTI 305
+ ++ L GG +
Sbjct: 825 MTQ---QLMNLAGGAVVL 839
>gi|169234807 histone deacetylase 7 isoform a [Homo sapiens]
Length = 991
Score = 108 bits (270), Expect = 1e-23
Identities = 85/318 (26%), Positives = 138/318 (43%), Gaps = 61/318 (19%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKF-----LRSIRPD 82
HP RI+ + L GL + E R KA+ EE+ HS+ ++ L ++ D
Sbjct: 580 HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD 639
Query: 83 NMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGG-SVASAVKLNKQQTDIAVNWAGGL-- 139
N QR F L GG V + N+ + A WA G
Sbjct: 640 NGKLAGLLAQRM--------------FVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVT 685
Query: 140 ----------------------HHAKKSEASGFCYVNDIVLAILELLKYHQ--RVLYIDI 175
HHA S A GFC+ N + +A +L + + ++L +D
Sbjct: 686 DLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDW 745
Query: 176 DIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID 233
D+HHG+G ++ FY V+ +S H++ G +FPG+G + ++GAG G+ + VN G+D
Sbjct: 746 DVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLD 805
Query: 234 ----DESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGD--RLGCFNLTIKGHAKCVEF 287
D Y A F+ V+ + F P V++ G D+ G LG ++++ AKC +
Sbjct: 806 PPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS----AKCFGY 861
Query: 288 VKSFNLPMLMLGGGGYTI 305
+ ++ L GG +
Sbjct: 862 MTQ---QLMNLAGGAVVL 876
>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
Length = 1123
Score = 105 bits (263), Expect = 7e-23
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 46/291 (15%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E R KA +E+ HS+ Y L P N +
Sbjct: 705 HPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSE-YHTLLYGTSPLNRQKL 763
Query: 88 SKQMQRFNVGEDCPVFDGLFEFCQLSTGG-SVASAVKLNKQQTDIAVNWAGGL------- 139
+ + + + L GG V S N+ + AV A G
Sbjct: 764 DSKKLLGPISQKM--------YAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFK 815
Query: 140 -----------------HHAKKSEASGFCYVNDIVLA--ILELLKYHQRVLYIDIDIHHG 180
HHA++S A GFC+ N + + +L+ +VL +D DIHHG
Sbjct: 816 VAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHG 875
Query: 181 DGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID----D 234
+G ++AFY V+ +S H+Y G +FPG+G ++G G G Y VN G+D D
Sbjct: 876 NGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGD 935
Query: 235 ESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSG--DRLGCFNLTIK--GH 281
Y F+ V+ + F P V++ G D++ G LG +++T + GH
Sbjct: 936 VEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGH 986
>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
Length = 1122
Score = 105 bits (263), Expect = 7e-23
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 46/291 (15%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E R KA +E+ HS+ Y L P N +
Sbjct: 704 HPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSE-YHTLLYGTSPLNRQKL 762
Query: 88 SKQMQRFNVGEDCPVFDGLFEFCQLSTGG-SVASAVKLNKQQTDIAVNWAGGL------- 139
+ + + + L GG V S N+ + AV A G
Sbjct: 763 DSKKLLGPISQKM--------YAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFK 814
Query: 140 -----------------HHAKKSEASGFCYVNDIVLA--ILELLKYHQRVLYIDIDIHHG 180
HHA++S A GFC+ N + + +L+ +VL +D DIHHG
Sbjct: 815 VAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHG 874
Query: 181 DGVEEAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID----D 234
+G ++AFY V+ +S H+Y G +FPG+G ++G G G Y VN G+D D
Sbjct: 875 NGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGD 934
Query: 235 ESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSG--DRLGCFNLTIK--GH 281
Y F+ V+ + F P V++ G D++ G LG +++T + GH
Sbjct: 935 VEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGH 985
>gi|153085395 histone deacetylase 4 [Homo sapiens]
Length = 1084
Score = 104 bits (259), Expect = 2e-22
Identities = 88/305 (28%), Positives = 141/305 (46%), Gaps = 44/305 (14%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E R KA EE+ HS+ + L P N +
Sbjct: 675 HPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT-LLYGTNPLNRQKL 733
Query: 88 -SKQMQRFNVGEDCPVF----------DGLFEFCQLSTGGSVASAV----------KLNK 126
SK++ +G VF D + ++ + G+ AV +
Sbjct: 734 DSKKL----LGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGE 789
Query: 127 QQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLA--ILELLKYHQRVLYIDIDIHHGDGVE 184
+ AV G HHA++S GFCY N + +A +L+ ++L +D D+HHG+G +
Sbjct: 790 LKNGFAVVRPPG-HHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQ 848
Query: 185 EAFYTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNYPLRDGID----DESYE 238
+AFY+ V+ +S H+Y G +FPG+G ++G G G + VN G+D D Y
Sbjct: 849 QAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYL 908
Query: 239 AIFKPVMSKVMEMFQPSAVVLQCGSDSLSG--DRLGCFNLTIKGHAKCVEFVKSFNLPML 296
A F+ V+ + F P V++ G D++ G LG +NL+ A+C ++ ++
Sbjct: 909 AAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLS----ARCFGYLTK---QLM 961
Query: 297 MLGGG 301
L GG
Sbjct: 962 GLAGG 966
>gi|13128864 histone deacetylase 6 [Homo sapiens]
Length = 1215
Score = 102 bits (253), Expect = 1e-21
Identities = 83/308 (26%), Positives = 137/308 (44%), Gaps = 17/308 (5%)
Query: 15 YDGDVGNY--YYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDY 72
YD ++ N+ + HP P RI L GL + P A E+ HS +Y
Sbjct: 485 YDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEY 544
Query: 73 IKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGS--VASAVKLNKQQTD 130
+ LR+ E ++ F+ CP F QL+TG + + AV +
Sbjct: 545 VGHLRATEKMKTRELHRESSNFDSIYICP---STFACAQLATGAACRLVEAVLSGEVLNG 601
Query: 131 IAVNWAGGLHHAKKSEASGFCYVNDIVLAI--LELLKYHQ-RVLYIDIDIHHGDGVEEAF 187
AV G HHA++ A GFC+ N + +A + + H R+L +D D+HHG+G + F
Sbjct: 602 AAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660
Query: 188 YTTDRVMTVSFHKY--GEYFP--GTGDLRDIGAGKGKYYAVNYPLR-DGIDDESYEAIFK 242
V+ VS H+Y G +FP G IG G + VN + D Y A +
Sbjct: 661 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720
Query: 243 PVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSF-NLPMLMLGGG 301
++ + F P V++ G D+ GD LG ++ +G+A + + ++++ G
Sbjct: 721 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780
Query: 302 GYTIRNVA 309
GY + +++
Sbjct: 781 GYNLTSIS 788
Score = 94.4 bits (233), Expect = 2e-19
Identities = 82/292 (28%), Positives = 124/292 (42%), Gaps = 16/292 (5%)
Query: 29 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYS 88
P P R+ L+ GL + ++ A EE+ HS +YI + + + N E
Sbjct: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165
Query: 89 KQMQRFNVGEDCPVFDGLFEFCQLSTGGSV---ASAVKLNKQQTDIAVNWAGGLHHAKKS 145
+ D C GSV AV + + +A+ G HHA+ S
Sbjct: 166 VLADTY----DSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHS 220
Query: 146 EASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY-- 201
G+C N + +A + H+ RVL +D D+HHG G + F V+ S H+Y
Sbjct: 221 LMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQ 280
Query: 202 GEYFP--GTGDLRDIGAGKGKYYAVNYPLRD-GIDDESYEAIFKPVMSKVMEMFQPSAVV 258
G ++P + G G+G+ Y +N P G+ D Y A F V+ V FQP V+
Sbjct: 281 GRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVL 340
Query: 259 LQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLG-GGGYTIRNVA 309
+ G D+L GD G T G A+ + L+L GGY +R +A
Sbjct: 341 VAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA 392
>gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]
Length = 669
Score = 95.5 bits (236), Expect = 9e-20
Identities = 80/304 (26%), Positives = 134/304 (44%), Gaps = 28/304 (9%)
Query: 31 KPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQ 90
+P R+ + L GL ++ +A+ EE+ HS +Y+ +R + E
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQAL 86
Query: 91 MQRFNVGEDCPVFDGLFEFCQLSTGGSV--ASAVKLNKQQTDIAVNWAGGLHHAKKSEAS 148
+F+ P F +L+ G + AV Q +A+ G HH +++ A+
Sbjct: 87 SGQFDAIYFHP---STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAAN 142
Query: 149 GFCYVNDIVLAILELLKYH--QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEY 204
GFC N++ +A + H R+L +D D+HHG G++ F V+ S+H+Y G +
Sbjct: 143 GFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRF 202
Query: 205 FP--GTGDLRDIGAGKGKYYAVNYPLRD-GIDDESYEAIFKPVMSKVMEMFQPSAVVLQC 261
+P D +G G+G + VN P G+ + Y A F ++ + F P V++
Sbjct: 203 WPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSA 262
Query: 262 GSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG-------GGYTIRNVAR--CW 312
G DS GD G T +C F L ++ GG GGY + ++A C
Sbjct: 263 GFDSAIGDPEGQMQAT----PEC--FAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCM 316
Query: 313 TYET 316
T +T
Sbjct: 317 TVQT 320
>gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]
Length = 649
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/220 (26%), Positives = 100/220 (45%), Gaps = 13/220 (5%)
Query: 31 KPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQ 90
+P R+ + L GL ++ +A+ EE+ HS +Y+ +R + E
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQAL 86
Query: 91 MQRFNVGEDCPVFDGLFEFCQLSTGGSV--ASAVKLNKQQTDIAVNWAGGLHHAKKSEAS 148
+F+ P F +L+ G + AV Q +A+ G HH +++ A+
Sbjct: 87 SGQFDAIYFHP---STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAAN 142
Query: 149 GFCYVNDIVLAILELLKYH--QRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEY 204
GFC N++ +A + H R+L +D D+HHG G++ F V+ S+H+Y G +
Sbjct: 143 GFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRF 202
Query: 205 FP--GTGDLRDIGAGKGKYYAVNYPLRD-GIDDESYEAIF 241
+P D +G G+G + VN P G+ + Y A F
Sbjct: 203 WPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAF 242
>gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]
Length = 879
Score = 77.0 bits (188), Expect = 3e-14
Identities = 59/212 (27%), Positives = 92/212 (43%), Gaps = 40/212 (18%)
Query: 28 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEY 87
HP RI+ + L GL K E + KA+ EE+ HS+ + + N +
Sbjct: 654 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHHSLLYGT----NPLDG 709
Query: 88 SKQMQRFNVGEDCPVFDGLFEFCQLSTGG--------------------------SVASA 121
K R +G+D F F L GG +AS
Sbjct: 710 QKLDPRILLGDDSQKF-----FSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASK 764
Query: 122 VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHH 179
V + + AV G HHA++S A GFC+ N + + L ++L +D+D+HH
Sbjct: 765 VASGELKNGFAVVRPPG-HHAEESTAMGFCFFNSVAITAKYLRDQLNISKILIVDLDVHH 823
Query: 180 GDGVEEAFYTTDRVMTVSFHKY--GEYFPGTG 209
G+G ++AFY ++ +S H+Y G +FPG+G
Sbjct: 824 GNGTQQAFYADPSILYISLHRYDEGNFFPGSG 855
>gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens]
Length = 347
Score = 75.5 bits (184), Expect = 1e-13
Identities = 61/200 (30%), Positives = 89/200 (44%), Gaps = 17/200 (8%)
Query: 114 TGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYHQRV 170
TGG++ + KL ++ A+N GG HH GFC DI LAI E ++ R
Sbjct: 118 TGGTIMAG-KLAVER-GWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRA 175
Query: 171 LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRD 230
ID+D H G+G E F RV + + +PG + K L
Sbjct: 176 TIIDLDAHQGNGHERDFMDDKRVYIMDVYN-RHIYPGDRFAKQAIRRK-------VELEW 227
Query: 231 GIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVE---- 286
G +D+ Y + + K ++ P VV G+D L GDRLG +++ G K E
Sbjct: 228 GTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFR 287
Query: 287 FVKSFNLPMLMLGGGGYTIR 306
V+ +P+LM+ GGY R
Sbjct: 288 MVRGRRVPILMVTSGGYQKR 307
>gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens]
Length = 296
Score = 75.5 bits (184), Expect = 1e-13
Identities = 61/200 (30%), Positives = 89/200 (44%), Gaps = 17/200 (8%)
Query: 114 TGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI---LELLKYHQRV 170
TGG++ + KL ++ A+N GG HH GFC DI LAI E ++ R
Sbjct: 67 TGGTIMAG-KLAVER-GWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRA 124
Query: 171 LYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRD 230
ID+D H G+G E F RV + + +PG + K L
Sbjct: 125 TIIDLDAHQGNGHERDFMDDKRVYIMDVYN-RHIYPGDRFAKQAIRRK-------VELEW 176
Query: 231 GIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVE---- 286
G +D+ Y + + K ++ P VV G+D L GDRLG +++ G K E
Sbjct: 177 GTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFR 236
Query: 287 FVKSFNLPMLMLGGGGYTIR 306
V+ +P+LM+ GGY R
Sbjct: 237 MVRGRRVPILMVTSGGYQKR 256
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 7/97 (7%)
Query: 391 EESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEG-GRKNSSNFKKAKRVKTEDEK 449
E + ++ DK+ S + K + +EE +D++ E +G +K + KK K+ +D+K
Sbjct: 414 ESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDK 473
Query: 450 EKDPEEKKEVTEEE------KTKEEKPEAKGVKEEVK 480
+KD ++ E TE E K K+ E KG K+++K
Sbjct: 474 KKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIK 510
Score = 43.1 bits (100), Expect = 6e-04
Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 6/151 (3%)
Query: 333 YFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEE 392
Y +Y D K + S+ ++ +K +++ +N++ V+ DA +
Sbjct: 280 YTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGD 339
Query: 393 SGDEDEDDPDKRISICSSDKRIACEE--EFSDSEE-EGEGGRKNSSNFKKAKRVKTEDEK 449
S DE +D + + DK+ ++ E +D+E + + R +S N KKA + D+K
Sbjct: 340 SKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASK---NDDK 396
Query: 450 EKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK 480
+KD ++ T+ E E K K K++ K
Sbjct: 397 KKDAKKITFSTDSESELESKESQKDEKKDKK 427
Score = 33.9 bits (76), Expect = 0.34
Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 9/98 (9%)
Query: 392 ESGDEDEDDPD----KRISICSSDKRIACEEEFS-DSEEEGEGGRKNSSNFKKAKRVKTE 446
ESGD + D K+ S K+ A + FS DSE E E K K KT+
Sbjct: 373 ESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTD 432
Query: 447 DEKE-KDPEEKKEVTEEEK---TKEEKPEAKGVKEEVK 480
++K K+ EE + E K K +K E KG K+ K
Sbjct: 433 NKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKK 470
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 13/106 (12%)
Query: 382 QAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKN-------- 433
+ +PE+A+P + D+D +DP + + I DK +A E+ + K+
Sbjct: 779 EEMPENALPSDEDDKDPNDPYRALDI-DLDKPLADSEKLPIQKHRNTETSKSPEKDVPMV 837
Query: 434 -SSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEE 478
+ K K+ K EKE+D E+KK E+EK K KP+ K ++E
Sbjct: 838 EKKSKKPKKKEKKHKEKERDKEKKK---EKEKKKSPKPKKKKHRKE 880
Score = 31.2 bits (69), Expect = 2.2
Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Query: 389 IPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKA---KRVKT 445
I + E P+K + + + ++E E+E + +K KK+ K+ K
Sbjct: 818 IQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKH 877
Query: 446 EDEKEKDPEEKKEVTEEEKTKEE---KPEAKGVKEEVKL 481
EKE+ + KK+ ++ EE +P G EE +L
Sbjct: 878 RKEKEERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQL 916
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 46.2 bits (108), Expect = 7e-05
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 19/112 (16%)
Query: 377 PGVQMQAIP-------EDAIPEESGDEDEDDPDKRISICSSDKR---IACEEEFSDSEEE 426
PGV+ P E++ EE EDED +R + S D+R A ++E + EEE
Sbjct: 320 PGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEE 379
Query: 427 GEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEE 478
KK + +K ++EKE++ EE+ + EEE+ K E +G ++
Sbjct: 380 ---------EMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKD 422
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 45.8 bits (107), Expect = 9e-05
Identities = 27/89 (30%), Positives = 47/89 (52%)
Query: 392 ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEK 451
E +E E++ +K K E+E +E E ++ KK KR + + ++E+
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE 73
Query: 452 DPEEKKEVTEEEKTKEEKPEAKGVKEEVK 480
+ EE++E EEEK +EEK E + K++ K
Sbjct: 74 EREEEEEEEEEEKEEEEKEEGRRRKKKKK 102
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 391 EESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKE 450
E+ G E +KR +K+ +E E+E E ++ KK + + E+E+E
Sbjct: 24 EKEGKRKEKRKEKRKE---KEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 451 KDPEEKKEVTEEEKTKEEKPEAKGVKEE 478
++ EEK+E +EE + +K + + KEE
Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Score = 34.3 bits (77), Expect = 0.26
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 392 ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEK 451
E E E++ KR K EEE + EEE E ++ + +R K + + K
Sbjct: 50 EKRKEKEEEEKKRKRKRKKKKE---EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106
Query: 452 DPEEKKEVTEEEKTKEE 468
+ EE+K+ KTK++
Sbjct: 107 EEEEEKKKKRRRKTKKK 123
Score = 32.3 bits (72), Expect = 0.98
Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 438 KKAKRVKTEDEKEKDPEEKKEVTEEE-KTKEEKPEAKGVKEEVK 480
KK K+ K E E+ ++ EE +E E+E K KE++ E + KE+ K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK 44
Score = 32.3 bits (72), Expect = 0.98
Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
Query: 438 KKAKRVKTEDEKEKDPEEKKEVTEEEKTKE---EKPEAKGVKEEVK 480
KK + +TE+ +E + EE+KE +EK KE EK + K KE K
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51
Score = 29.6 bits (65), Expect = 6.4
Identities = 13/43 (30%), Positives = 26/43 (60%)
Query: 431 RKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAK 473
+K + + +TE+E+EK+ + K++ E+ K KE+K + K
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK 47
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 45.4 bits (106), Expect = 1e-04
Identities = 30/115 (26%), Positives = 57/115 (49%), Gaps = 11/115 (9%)
Query: 357 EYLEKIKQRLFENLRMLPHAPGVQMQAI----------PEDAIPEESGDEDEDDPDKRIS 406
E L+ +K +L E +++ + QA+ E+ EE DE E+D ++++
Sbjct: 592 EKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVE 651
Query: 407 ICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTE 461
++ + EEE + EEE EG ++ + ++ ++T+DEKE D E +E
Sbjct: 652 KEEKEEELE-EEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENNDGSSE 705
Score = 38.1 bits (87), Expect = 0.018
Identities = 23/64 (35%), Positives = 33/64 (51%)
Query: 417 EEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVK 476
E+ F + EEE E S + K K E E+E + EE+KE EEE+ +E E
Sbjct: 625 EDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSS 684
Query: 477 EEVK 480
EE++
Sbjct: 685 EEIE 688
Score = 30.8 bits (68), Expect = 2.9
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 15/139 (10%)
Query: 355 TNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDD----------PDKR 404
TN LE +KQR +++ P A Q + + I ++ G + +++ K+
Sbjct: 524 TNRELEALKQRFWKHAN--PAAKPRAGQTVNVNVIVKDMGTDGKEELKADVVPVTLAPKK 581
Query: 405 ISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEK--EKDPEEKKEVTEE 462
+ S K + +E R+ K+ K ++E E++ EE++E+T+E
Sbjct: 582 LDGASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDE 641
Query: 463 -EKTKEEKPEAKGVKEEVK 480
E+ EEK E + +EE++
Sbjct: 642 SEEDGEEKVEKEEKEEELE 660
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 6/92 (6%)
Query: 382 QAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSN----- 436
+ +PE+A+P + D+D +DP + + I DK +A E+ + K+
Sbjct: 688 EEMPENALPSDEDDKDPNDPYRALDI-DLDKPLADSEKLPIQKHRNTETSKSPEKDVPMV 746
Query: 437 FKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEE 468
KK+K+ K +++K K+ E KE +E++ K E
Sbjct: 747 EKKSKKPKKKEKKHKEKERDKEKKKEKEKKAE 778
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/104 (30%), Positives = 57/104 (54%), Gaps = 16/104 (15%)
Query: 386 EDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGR--KNSSNFKKAKRV 443
++++ E +E E++ ++ ++ + EEE EEEGE + K KK K+
Sbjct: 2240 QESLSSEEEEEREEEEERE------EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293
Query: 444 KTED---EKEKDPEEKKEVTEEEKT-----KEEKPEAKGVKEEV 479
K ++ EKE+ EEK+E+ EE+T +EE+ E+ ++EEV
Sbjct: 2294 KKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Query: 399 DDPDKRISICSSDKRIACEEEFSDSEE--EGEGGRKNSSNFKKAKRVKTEDEKEKDPEEK 456
D+ +K+ S+ S ++ EEE + EE E E RK ++ + K E+EK+K +EK
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 457 K--EVTEEEKTKEEKPEAKGVKEEVKLA 482
K EV E+E+ EEK E +E L+
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Score = 38.9 bits (89), Expect = 0.010
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 399 DDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKE 458
D P ++ S S + EE FS+ E + + + + E+E+E++ EE +E
Sbjct: 2207 DKPKEKFS--SQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVRE 2264
Query: 459 VTEEEKTKEEKPEAKGVKEE 478
EE K +EE E + KEE
Sbjct: 2265 EEEERKEEEEGEEKQVEKEE 2284
Score = 33.5 bits (75), Expect = 0.44
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 392 ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEK 451
ES + ++ + + + ++ EEE EEE + ++ K + +EK+
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 452 D-PEEKKEVTEEEKTKEEKPEAKGVKEE 478
+ EE+K+ ++EK KEE E + V EE
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEE 2308
Score = 30.8 bits (68), Expect = 2.9
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 412 KRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPE 471
K I+ +EE ++ + GRK +K ++K E KE+ + E EE T EEK
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEE--RDMSEEVEEMATLEEKV- 1441
Query: 472 AKGVKEEVKL 481
VK+E KL
Sbjct: 1442 ---VKQEGKL 1448
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/90 (22%), Positives = 46/90 (51%), Gaps = 3/90 (3%)
Query: 394 GDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDP 453
GD+ ++ ++ S++ + E E E E + + ++ + + E+E+ ++
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 454 EEKK---EVTEEEKTKEEKPEAKGVKEEVK 480
EE++ E EE++ ++E+ E K K+E K
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Score = 30.0 bits (66), Expect = 4.9
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 13/78 (16%)
Query: 418 EEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEK-KEVTEEEK------------ 464
EE+ E + +K + V E+E ++ EEK ++VTEE++
Sbjct: 1519 EEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIH 1578
Query: 465 TKEEKPEAKGVKEEVKLA 482
K + E K +EE KLA
Sbjct: 1579 RKRARAEKKRAQEERKLA 1596
Score = 29.6 bits (65), Expect = 6.4
Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 391 EESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKE 450
EE E+E+ +K++ +K+ +E+ + +E E F++ + + +E+E E
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE------EVFEEKEEIMSEEETE 2319
Query: 451 K---DPEEKKEVTEEEKTKEEKPEAKGVKE 477
+ EE++ + EE+ EK K K+
Sbjct: 2320 SLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349
Score = 29.3 bits (64), Expect = 8.3
Identities = 20/79 (25%), Positives = 35/79 (44%)
Query: 395 DEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPE 454
DE+E ++ +S +K EE +EE + R + + K+ E+ K E
Sbjct: 1540 DEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599
Query: 455 EKKEVTEEEKTKEEKPEAK 473
EK E + +EE+ A+
Sbjct: 1600 EKLAQEERQLAQEERKLAQ 1618
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 15/105 (14%)
Query: 391 EESGDEDEDDPDKRISICSSDKRIACEEE---------FSDSEEEG-----EGGRKNSSN 436
+E G ++ED P K K + + + SDSEEEG E RK N
Sbjct: 234 DEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRN 293
Query: 437 FKKA-KRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK 480
F+ A +R + + EK+ ++K EE+ E++ + +G K EVK
Sbjct: 294 FQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVK 338
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 15/105 (14%)
Query: 391 EESGDEDEDDPDKRISICSSDKRIACEEE---------FSDSEEEG-----EGGRKNSSN 436
+E G ++ED P K K + + + SDSEEEG E RK N
Sbjct: 234 DEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRN 293
Query: 437 FKKA-KRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK 480
F+ A +R + + EK+ ++K EE+ E++ + +G K EVK
Sbjct: 294 FQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVK 338
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 43.5 bits (101), Expect = 4e-04
Identities = 46/152 (30%), Positives = 70/152 (46%), Gaps = 32/152 (21%)
Query: 361 KIKQRLFENLRMLPHA---PGVQMQAIPEDAIPEESGDEDEDDPDKRIS----ICSSDKR 413
K+KQR + P A P ++ ++ PE + + P K S + DK
Sbjct: 534 KLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKP 593
Query: 414 IACEEEFSDSEEE-----------GEGGRKNSSNFK----------KAKRVKTEDEKEKD 452
I E + S +E+E E K +++ K K +VK ED+KE+
Sbjct: 594 IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEK 653
Query: 453 PEEKKEVT-EEEKT---KEEKPEAKGVKEEVK 480
+ KKEV +E+KT KEEKP+ + VK+EVK
Sbjct: 654 EKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVK 685
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Query: 386 EDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKT 445
E + E E+++ P K ++ + + ++E +EE + K ++ K K
Sbjct: 641 ETKVKPEDKKEEKEKPKKEVA--KKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKK 698
Query: 446 EDEKEKDPEE-KKEVTEEEKTKEEKPEAKGVKEEVK 480
E +KE P+E KKEV +EEK KE K E K K+E+K
Sbjct: 699 EVKKETPPKEVKKEVKKEEK-KEVKKEEKEPKKEIK 733
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Query: 376 APGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSS 435
A V+ +A E + +E+ + ED +++ K +A +E+ + ++E E +K
Sbjct: 625 ATDVKPKAAKEKTVKKETKVKPEDKKEEKEK---PKKEVAKKEDKTPIKKE-EKPKKEEV 680
Query: 436 NFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKE-EKPEAKGVKEEVK 480
+ K +K E++KE E KKE +E KE +K E K VK+E K
Sbjct: 681 KKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEK 726
Score = 33.1 bits (74), Expect = 0.58
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 12/100 (12%)
Query: 386 EDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEE------------GEGGRKN 433
E+ E +E E+D ++ + + +S +EE + +E + G+ +
Sbjct: 943 EEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEE 1002
Query: 434 SSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAK 473
+ K + E+E D E+K E EE+ + EK EA+
Sbjct: 1003 DMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAE 1042
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 42.7 bits (99), Expect = 7e-04
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
Query: 386 EDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKT 445
+D P+ D ++ K+ I S ++ EEE + EEE E + +
Sbjct: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDE------------EEEEE 280
Query: 446 EDEKEKDPEEKKEVTEEEKTKEEKPEA 472
E+E+E++ EE++E EEE+ +EE+ EA
Sbjct: 281 EEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/108 (24%), Positives = 56/108 (51%), Gaps = 7/108 (6%)
Query: 377 PGVQ--MQAIPEDAIPEESGDE----DEDDPDKRISICSSDKRIACEEEFSDSEEEGEGG 430
PG+ +Q E A EE G++ +D ++ + + + + C + D+ E
Sbjct: 192 PGIVHLLQEAAEGAASEE-GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSK 250
Query: 431 RKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEE 478
+K + ++ + E+E+E++ +E++E EEE+ +EE+ E + +EE
Sbjct: 251 QKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Score = 40.0 bits (92), Expect = 0.005
Identities = 23/93 (24%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 390 PEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEK 449
PE++ + E ++ +C A EE S+++G + ++ + + E+++
Sbjct: 218 PEDAEEVVEVTTERSQDLCPQSLEDAASEE--SSKQKGILSHEEEDEEEEEEEEEEEEDE 275
Query: 450 EKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA 482
E++ EE++E EEE+ +EE+ E + +EE + A
Sbjct: 276 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 29.3 bits (64), Expect = 8.3
Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 4/86 (4%)
Query: 385 PEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVK 444
PE ++ E +D+ D D S + E E D G G + KA++V+
Sbjct: 338 PEYSVIVEVRSDDDKDEDTH----SRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVR 393
Query: 445 TEDEKEKDPEEKKEVTEEEKTKEEKP 470
T E P E+ ++ E K KP
Sbjct: 394 TVCEPGCPPAEQSQLGLGEPGKAAKP 419
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 42.7 bits (99), Expect = 7e-04
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 382 QAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAK 441
Q +PE P G ++ I+I SSD+ EEE + EEE E ++ ++ +
Sbjct: 859 QLVPEGT-PGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE 917
Query: 442 RVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKL 481
E+E+E++ E ++E EEE EE+ E + +EE +L
Sbjct: 918 EEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Score = 37.0 bits (84), Expect = 0.040
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 387 DAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTE 446
D EE +E+E++ ++ ++ EEE+ + EEE E + F++ + E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE--EEFEEEFEEEEGELEE 944
Query: 447 DEKEKDPEEKKEVTEEE 463
+E+E+D EE++E+ E E
Sbjct: 945 EEEEEDEEEEEELEEVE 961
Score = 34.3 bits (77), Expect = 0.26
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Query: 383 AIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKR 442
A+ ED DE++ ++ ++ EE+F + EE+ E F++ +
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEE------EYFEEEEE 926
Query: 443 VKTEDEKEKDPEE-KKEVTEEEKTKEEKPEAKGVKE 477
+ E E+E + EE + E EEE+ +EE+ E + V++
Sbjct: 927 EEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,832,555
Number of Sequences: 37866
Number of extensions: 997026
Number of successful extensions: 17113
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 285
Number of HSP's successfully gapped in prelim test: 372
Number of HSP's that attempted gapping in prelim test: 8158
Number of HSP's gapped (non-prelim): 5008
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.