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Search of human proteins with 4505121
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
(580 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] 1181 0.0
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 77 3e-14
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 77 3e-14
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] 50 7e-06
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 49 2e-05
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 49 2e-05
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 39 0.013
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 39 0.013
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 39 0.013
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 39 0.013
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 39 0.013
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 38 0.029
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 36 0.11
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 35 0.14
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 34 0.32
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 34 0.42
gi|167614502 protein phosphatase 1, regulatory (inhibitor) subun... 34 0.42
gi|150170670 piccolo isoform 2 [Homo sapiens] 34 0.42
gi|150378539 piccolo isoform 1 [Homo sapiens] 34 0.42
gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo sa... 33 0.55
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap... 33 0.55
gi|157785668 coiled-coil domain containing 39 [Homo sapiens] 33 0.72
gi|119395734 breast cancer 2, early onset [Homo sapiens] 32 1.2
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 32 1.2
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 32 1.2
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ... 32 1.2
gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c ... 32 1.2
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 32 1.2
gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d ... 32 1.2
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 32 1.6
>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
Length = 580
Score = 1181 bits (3055), Expect = 0.0
Identities = 580/580 (100%), Positives = 580/580 (100%)
Query: 1 MGTTGLESLSLGDRGAAPTVTSSERLVPDPPNDLRKEDVAMELERVGEDEEQMMIKRSSE 60
MGTTGLESLSLGDRGAAPTVTSSERLVPDPPNDLRKEDVAMELERVGEDEEQMMIKRSSE
Sbjct: 1 MGTTGLESLSLGDRGAAPTVTSSERLVPDPPNDLRKEDVAMELERVGEDEEQMMIKRSSE 60
Query: 61 CNPLLQEPIASAQFGATAGTECRKSVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRS 120
CNPLLQEPIASAQFGATAGTECRKSVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRS
Sbjct: 61 CNPLLQEPIASAQFGATAGTECRKSVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRS 120
Query: 121 KSSLANYLHKNGETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRT 180
KSSLANYLHKNGETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRT
Sbjct: 121 KSSLANYLHKNGETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRT 180
Query: 181 RSKCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPKGKVTILKG 240
RSKCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPKGKVTILKG
Sbjct: 181 RSKCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPKGKVTILKG 240
Query: 241 IPIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETL 300
IPIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETL
Sbjct: 241 IPIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETL 300
Query: 301 SVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGT 360
SVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGT
Sbjct: 301 SVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGT 360
Query: 361 KVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSS 420
KVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSS
Sbjct: 361 KVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSS 420
Query: 421 KYNKEALSPPRRKAFKKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWK 480
KYNKEALSPPRRKAFKKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWK
Sbjct: 421 KYNKEALSPPRRKAFKKWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWK 480
Query: 481 FLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKY 540
FLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKY
Sbjct: 481 FLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKY 540
Query: 541 GNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS 580
GNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS
Sbjct: 541 GNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS 580
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/70 (55%), Positives = 49/70 (70%), Gaps = 1/70 (1%)
Query: 85 SVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFT 144
++P GW R +KQR G++AG++DVY I+PQG FRSK L Y K G+TSL P DFDFT
Sbjct: 111 TLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFT 170
Query: 145 VLSKRGIKSR 154
V + RG SR
Sbjct: 171 V-TGRGSPSR 179
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 77.4 bits (189), Expect = 3e-14
Identities = 39/70 (55%), Positives = 49/70 (70%), Gaps = 1/70 (1%)
Query: 85 SVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFT 144
++P GW R +KQR G++AG++DVY I+PQG FRSK L Y K G+TSL P DFDFT
Sbjct: 99 TLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFT 158
Query: 145 VLSKRGIKSR 154
V + RG SR
Sbjct: 159 V-TGRGSPSR 167
>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
Length = 291
Score = 49.7 bits (117), Expect = 7e-06
Identities = 29/61 (47%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 81 ECRKSVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPED 140
EC ++P GWER R G +AG DV++ SP G KFRSK LA YL G L D
Sbjct: 7 EC-PALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYL--GGSMDLSTFD 63
Query: 141 F 141
F
Sbjct: 64 F 64
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/59 (44%), Positives = 34/59 (57%), Gaps = 4/59 (6%)
Query: 85 SVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDF 143
++P GW++ R G +AG+ DVY+ SP G KFRSK LA YL + S FDF
Sbjct: 154 ALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLS----SFDF 208
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/59 (44%), Positives = 34/59 (57%), Gaps = 4/59 (6%)
Query: 85 SVPCGWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDF 143
++P GW++ R G +AG+ DVY+ SP G KFRSK LA YL + S FDF
Sbjct: 154 ALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLS----SFDF 208
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148
GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K
Sbjct: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
Query: 149 RGI 151
+GI
Sbjct: 66 QGI 68
>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
Length = 503
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148
GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K
Sbjct: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
Query: 149 RGI 151
+GI
Sbjct: 66 QGI 68
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148
GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K
Sbjct: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
Query: 149 RGI 151
+GI
Sbjct: 66 QGI 68
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148
GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K
Sbjct: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
Query: 149 RGI 151
+GI
Sbjct: 66 QGI 68
>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
sapiens]
Length = 549
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 8/63 (12%)
Query: 89 GWERVVKQRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSLKPEDFDFTVLSK 148
GW+R R G T GR D Y+ SP G + RSK L YL + +L FDF K
Sbjct: 14 GWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----FDF----K 65
Query: 149 RGI 151
+GI
Sbjct: 66 QGI 68
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 37.7 bits (86), Expect = 0.029
Identities = 67/326 (20%), Positives = 130/326 (39%), Gaps = 30/326 (9%)
Query: 129 HKNGETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRTRSKCKKDV 188
H+N E S K + T + K+ K+CS ++ N+ + L T++ KKD+
Sbjct: 167 HEN-EQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEF-LHTKNNPKKDL 224
Query: 189 FMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNF----RKVRKPKGKVTILKGIPI- 243
+S+ + E ++ L+L + +NF R + K LK
Sbjct: 225 KRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYT 284
Query: 244 -KKTKKGCRKSCSGFVQ--SDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETL 300
K TKK +KS + D+K++S K + + + + + D +++G +
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDER 344
Query: 301 SVTSEENSLVKKKER---------SLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDT 351
T ++ +KK ++ S + S + + K S D + + + T
Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404
Query: 352 FLESEEIGTKVEVVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIER 411
F E +++E E ++ D K+ S+ DN S + D E+ D+ P+ ++
Sbjct: 405 FSTDSE--SELESKESQKDEKKD--KKDSKTDNKKS-VKND---EESTDADSEPKGDSKK 456
Query: 412 RKTSLYFSSKYNKEALSPPRRKAFKK 437
K K K++ ++K KK
Sbjct: 457 GKKD---EKKGKKDSKKDDKKKDAKK 479
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 5/72 (6%)
Query: 81 ECRKSVPCGWERVVKQRLFGKTAGRF--DVYFISPQGLKFRSKSSLANYLHKNGETSLKP 138
E R + GW+R + R FG GR +V + +P G K R + YL +NG +
Sbjct: 744 ELRIPLEYGWQRETRIRNFG---GRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISR 800
Query: 139 EDFDFTVLSKRG 150
++F F+ + G
Sbjct: 801 DNFSFSAKIRVG 812
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 35.4 bits (80), Expect = 0.14
Identities = 61/247 (24%), Positives = 94/247 (38%), Gaps = 43/247 (17%)
Query: 183 KCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPK-GKVTILKGI 241
K D P +S E ++G +++ VD + K GK I
Sbjct: 109 KSSTDNHEAPPTSEENSSNQGKDP------MIRNQRSVDPADSTTTHKESAGKKHIT--- 159
Query: 242 PIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQK-SQLDRTVCISDAGACGETL 300
P K+K CRKS +G + +V K+D P+ + S LD+T S T
Sbjct: 160 PAPKSKINCRKSTTG-------KSTVTRKSDKTGRPLEKSMSTLDKTSTSSHK----TTT 208
Query: 301 SVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYED--TFLESEEI 358
S + NS K+K S E+ T+ + + E +EK ED T + S+++
Sbjct: 209 SFHNSGNSQTKQKSTSF-------PEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKL 261
Query: 359 GTKV-----EVVERKEHLH-----TDILKRGSEMDNNCSPTRKDFTGEKIFQEDTI--PR 406
TK E + E T+ R + +N SP E+ E+T P
Sbjct: 262 LTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPA 321
Query: 407 TQIERRK 413
IE R+
Sbjct: 322 EPIENRE 328
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 18/140 (12%)
Query: 244 KKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETLSVT 303
K+ KK CR S S S +S + +D+E E Q + + S + T
Sbjct: 96 KRKKKSCRSS-----SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE 150
Query: 304 SEENSLVKKKERSLSSGS------NFCSEQKTSGIINKFCSAKDSEHNEKYEDTFL---- 353
SE VKKK++S + ++K S +K S++ S ++ ED
Sbjct: 151 SESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKR 210
Query: 354 ---ESEEIGTKVEVVERKEH 370
E E+ KV+ ++K+H
Sbjct: 211 RCEEREQAKEKVKKKKKKQH 230
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 33.9 bits (76), Expect = 0.42
Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 31/183 (16%)
Query: 183 KCKKDVFMPPSSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPK-GKVTILKGI 241
K D P +S E ++G +++ VD + K GK I
Sbjct: 171 KSSTDNHEAPPTSEENSSNQGKDP------MIRNQRSVDPADSTTTHKESAGKKHIT--- 221
Query: 242 PIKKTKKGCRKSCSGFVQSDSKRESVCNKADAESEPVAQK-SQLDRTVCISDAGACGETL 300
P K+K CRKS +G + +V K+D P+ + S LD+T S T
Sbjct: 222 PAPKSKINCRKSTTG-------KSTVTRKSDKTGRPLEKSMSTLDKTSTSSHK----TTT 270
Query: 301 SVTSEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYED--TFLESEEI 358
S + NS K+K S E+ T+ + + E +EK ED T + S+++
Sbjct: 271 SFHNSGNSQTKQKSTSF-------PEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKL 323
Query: 359 GTK 361
TK
Sbjct: 324 LTK 326
>gi|167614502 protein phosphatase 1, regulatory (inhibitor) subunit
3A [Homo sapiens]
Length = 1122
Score = 33.9 bits (76), Expect = 0.42
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 17/170 (10%)
Query: 267 VCNKADAESEPVAQKSQL-DRTV--CISDAGACGETLSVTSEENSLVKKKERSLSSGSNF 323
+C K + E EPV ++ +R + C+ + E+ SVTSEEN+ K +
Sbjct: 230 ICQKKEQEPEPVKPWKEVPNRQIKGCLKVKSSKEES-SVTSEENNFENPKNTDTYIPTII 288
Query: 324 CSEQKTSGIINKFCSAKD-----SEHNEKYEDTFLESEEIGTKVEVV-ERKEHLHTDILK 377
CS + + + KD EHNEK + + I T+ + + TD +
Sbjct: 289 CSHEDKEDLEASNRNVKDVNREHDEHNEKELELMINQHLIRTRSTASRDERNTFSTDPVN 348
Query: 378 RGSEMDNNCSPTRKDFTGE---KIFQEDTIPRTQIERR-KTSLYFSSKYN 423
++ + +K GE +FQ P + E K Y + KY+
Sbjct: 349 FPNKAE---GLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYS 395
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 10/138 (7%)
Query: 133 ETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRTRSKCKKDVFMPP 192
++ ++ +D D T R SR + + TS + + W++ TRS+ K V
Sbjct: 3442 DSGVQTDDEDAT---DRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYG 3498
Query: 193 SSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPK------GKVTILKGIPI-KK 245
S +E +++ LS +S + + V +R P KV I+K I +K
Sbjct: 3499 DSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEK 3558
Query: 246 TKKGCRKSCSGFVQSDSK 263
T KG C SD++
Sbjct: 3559 TYKGGSLGCQTEADSDTQ 3576
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 10/138 (7%)
Query: 133 ETSLKPEDFDFTVLSKRGIKSRYKDCSMAALTSHLQNQSNNSNWNLRTRSKCKKDVFMPP 192
++ ++ +D D T R SR + + TS + + W++ TRS+ K V
Sbjct: 3442 DSGVQTDDEDAT---DRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYG 3498
Query: 193 SSSSELQESRGLSNFTSTHLLLKEDEGVDDVNFRKVRKPK------GKVTILKGIPI-KK 245
S +E +++ LS +S + + V +R P KV I+K I +K
Sbjct: 3499 DSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEK 3558
Query: 246 TKKGCRKSCSGFVQSDSK 263
T KG C SD++
Sbjct: 3559 TYKGGSLGCQTEADSDTQ 3576
>gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
sapiens]
Length = 856
Score = 33.5 bits (75), Expect = 0.55
Identities = 30/135 (22%), Positives = 52/135 (38%), Gaps = 2/135 (1%)
Query: 262 SKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETLSVTSEENSLVKKKERSLSSGS 321
S E + A + ++S ++ S+ G GE +S E+ + + S
Sbjct: 566 SVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKS 625
Query: 322 NFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGTKVEVVERKEHLHTDILKRGSE 381
E TS I K S + YE+ S E+ +V + RK+H + K+ +
Sbjct: 626 TKYGEPITSEYIEVPLQEKRS-WEQTYEEEIFLSSELQEEVPTLSRKDHF-PETTKKEVQ 683
Query: 382 MDNNCSPTRKDFTGE 396
D C P + G+
Sbjct: 684 KDKPCEPKSQKIEGK 698
>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
sapiens]
Length = 1503
Score = 33.5 bits (75), Expect = 0.55
Identities = 30/135 (22%), Positives = 52/135 (38%), Gaps = 2/135 (1%)
Query: 262 SKRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETLSVTSEENSLVKKKERSLSSGS 321
S E + A + ++S ++ S+ G GE +S E+ + + S
Sbjct: 622 SVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKS 681
Query: 322 NFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGTKVEVVERKEHLHTDILKRGSE 381
E TS I K S + YE+ S E+ +V + RK+H + K+ +
Sbjct: 682 TKYGEPITSEYIEVPLQEKRS-WEQTYEEEIFLSSELQEEVPTLSRKDHF-PETTKKEVQ 739
Query: 382 MDNNCSPTRKDFTGE 396
D C P + G+
Sbjct: 740 KDKPCEPKSQKIEGK 754
>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
Length = 941
Score = 33.1 bits (74), Expect = 0.72
Identities = 21/94 (22%), Positives = 43/94 (45%)
Query: 304 SEENSLVKKKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGTKVE 363
S ++ L + +ER S S+F + ++ I C A++ E + + E+G +
Sbjct: 40 SLQDELREYEERINSMTSHFKNVKQELSITQSLCKARERETESEEHFKAIAQRELGRVKD 99
Query: 364 VVERKEHLHTDILKRGSEMDNNCSPTRKDFTGEK 397
++R E+ IL++ S+ +N + G K
Sbjct: 100 EIQRLENEMASILEKKSDKENGIFKATQKLDGLK 133
>gi|119395734 breast cancer 2, early onset [Homo sapiens]
Length = 3418
Score = 32.3 bits (72), Expect = 1.2
Identities = 52/223 (23%), Positives = 88/223 (39%), Gaps = 41/223 (18%)
Query: 36 KEDVAMELERVGEDEEQMMIKRSSECNPLLQEPIASAQFGATAGTECRKSVPCGWERVVK 95
K D+++ ++++ E M K + L PI++ FG + T K + + K
Sbjct: 972 KSDISLNIDKIPEKNNDYMNKWAG-----LLGPISNHSFGGSFRTASNKEIKLSEHNIKK 1026
Query: 96 QRLFGKTAGRFDVYFISPQGLKFRSKSSLANYLHKNGETSL-KPEDFDFTVLSKRGIKSR 154
++F K D+ P L + + N L + + L KP+ + TV +
Sbjct: 1027 SKMFFK-----DIEEQYPTSL---ACVEIVNTLALDNQKKLSKPQSIN-TVSAHLQSSVV 1077
Query: 155 YKDCSMAALTSHL--QNQSNNSNWNLRTRSKCKKDVFMPPSSSSELQESRGLSNFTS--- 209
DC + +T + Q NSN NL K + S+ L+ES FT
Sbjct: 1078 VSDCKNSHITPQMLFSKQDFNSNHNLTPSQKAE-----ITELSTILEESGSQFEFTQFRK 1132
Query: 210 -THLLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCR 251
+++L K V P+ ++TIL K T + CR
Sbjct: 1133 PSYILQKSTFEV----------PENQMTIL-----KTTSEECR 1160
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 32.3 bits (72), Expect = 1.2
Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 10/136 (7%)
Query: 312 KKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGTKVEVVERKEHL 371
KKE + E+KT+ K K +E++ +D +SE G K E E E
Sbjct: 285 KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE-- 342
Query: 372 HTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSSKYNKEALSPPR 431
E + + +G+ F E ++ ++ E + +EAL
Sbjct: 343 --------KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
Query: 432 RKAFKKWTPPRSPFNL 447
+ ++W P+ L
Sbjct: 395 KPKEEEWEKPKDAAGL 410
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 32.3 bits (72), Expect = 1.2
Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 10/136 (7%)
Query: 312 KKERSLSSGSNFCSEQKTSGIINKFCSAKDSEHNEKYEDTFLESEEIGTKVEVVERKEHL 371
KKE + E+KT+ K K +E++ +D +SE G K E E E
Sbjct: 285 KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE-- 342
Query: 372 HTDILKRGSEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRKTSLYFSSKYNKEALSPPR 431
E + + +G+ F E ++ ++ E + +EAL
Sbjct: 343 --------KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
Query: 432 RKAFKKWTPPRSPFNL 447
+ ++W P+ L
Sbjct: 395 KPKEEEWEKPKDAAGL 410
>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
[Homo sapiens]
Length = 355
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/56 (35%), Positives = 27/56 (48%)
Query: 212 LLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCRKSCSGFVQSDSKRESV 267
+L KE E VD V +K K GKV K KTK+ +K G + D+ E +
Sbjct: 143 VLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKI 198
>gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c
[Homo sapiens]
Length = 306
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/56 (35%), Positives = 27/56 (48%)
Query: 212 LLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCRKSCSGFVQSDSKRESV 267
+L KE E VD V +K K GKV K KTK+ +K G + D+ E +
Sbjct: 143 VLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKI 198
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/56 (35%), Positives = 27/56 (48%)
Query: 212 LLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCRKSCSGFVQSDSKRESV 267
+L KE E VD V +K K GKV K KTK+ +K G + D+ E +
Sbjct: 124 VLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKI 179
>gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d
[Homo sapiens]
Length = 287
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/56 (35%), Positives = 27/56 (48%)
Query: 212 LLLKEDEGVDDVNFRKVRKPKGKVTILKGIPIKKTKKGCRKSCSGFVQSDSKRESV 267
+L KE E VD V +K K GKV K KTK+ +K G + D+ E +
Sbjct: 124 VLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKI 179
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 32.0 bits (71), Expect = 1.6
Identities = 45/190 (23%), Positives = 79/190 (41%), Gaps = 18/190 (9%)
Query: 263 KRESVCNKADAESEPVAQKSQLDRTVCISDAGACGETLSVTSEENSLVKKKERSLSSGSN 322
KR+ + + +D E A++++LD + D L +N L++ K + SG
Sbjct: 79 KRKEIIDASDKEGMSPAKRTKLDDLALLEDLEK-QRALIKAELDNELMEGK---VQSGMG 134
Query: 323 FCSEQKTSGIINKFCSAKDSEHNEKYED---TFLESEEIGTKVEVVERKEHLHTDILKRG 379
+ SG S ++ E +EK + + S K+E+V+ K R
Sbjct: 135 LILQGYESG------SEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRS 188
Query: 380 SEMDNNCSPTRKDFTGEKIFQEDTIPRTQIERRK----TSLYFSSKYNKEALSPP-RRKA 434
E + S +K G +I +E T ER+K + S +++ SP RR++
Sbjct: 189 KERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRS 248
Query: 435 FKKWTPPRSP 444
+K RSP
Sbjct: 249 QEKIGKARSP 258
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,794,263
Number of Sequences: 37866
Number of extensions: 1030793
Number of successful extensions: 2431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 89
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.