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Search of human proteins with 4504935
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504935 keratin 85 [Homo sapiens]
(507 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504935 keratin 85 [Homo sapiens] 1011 0.0
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap... 789 0.0
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap... 789 0.0
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap... 789 0.0
gi|14318422 keratin 86 [Homo sapiens] 789 0.0
gi|169790841 keratin 83 [Homo sapiens] 783 0.0
gi|169790853 keratin, hair, basic, 1 [Homo sapiens] 778 0.0
gi|15431316 keratin, hair, basic, 4 [Homo sapiens] 579 e-165
gi|27477127 keratin 82 [Homo sapiens] 566 e-161
gi|153791158 keratin 75 [Homo sapiens] 453 e-127
gi|119395754 keratin 5 [Homo sapiens] 452 e-127
gi|5031839 keratin 6A [Homo sapiens] 449 e-126
gi|155969697 keratin 6C [Homo sapiens] 448 e-126
gi|119703753 keratin 6B [Homo sapiens] 445 e-125
gi|67782365 keratin 7 [Homo sapiens] 429 e-120
gi|4504919 keratin 8 [Homo sapiens] 429 e-120
gi|109255249 keratin 4 [Homo sapiens] 422 e-118
gi|28173564 keratin 73 [Homo sapiens] 422 e-118
gi|109148552 keratin 3 [Homo sapiens] 418 e-117
gi|15618995 keratin 71 [Homo sapiens] 416 e-116
gi|32567786 keratin 6L [Homo sapiens] 407 e-113
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 406 e-113
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 406 e-113
gi|148612803 keratin 6 irs4 [Homo sapiens] 403 e-112
gi|153791670 keratin 76 [Homo sapiens] 401 e-112
gi|119395750 keratin 1 [Homo sapiens] 397 e-110
gi|47132620 keratin 2 [Homo sapiens] 394 e-109
gi|89357932 keratin 5b [Homo sapiens] 367 e-101
gi|194018511 keratin 77 [Homo sapiens] 363 e-100
gi|226246665 keratin 72 isoform 2 [Homo sapiens] 349 3e-96
>gi|4504935 keratin 85 [Homo sapiens]
Length = 507
Score = 1011 bits (2614), Expect = 0.0
Identities = 507/507 (100%), Positives = 507/507 (100%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG 60
MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG
Sbjct: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG 60
Query: 61 SCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVK 120
SCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVK
Sbjct: 61 SCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVK 120
Query: 121 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLR 180
QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLR
Sbjct: 121 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLR 180
Query: 181 REAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKS 240
REAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKS
Sbjct: 181 REAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKS 240
Query: 241 DLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYD 300
DLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYD
Sbjct: 241 DLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYD 300
Query: 301 DVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQR 360
DVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQR
Sbjct: 301 DVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQR 360
Query: 361 AKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEI 420
AKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEI
Sbjct: 361 AKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEI 420
Query: 421 ATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITV 480
ATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITV
Sbjct: 421 ATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITV 480
Query: 481 VAPDSCAPCQPRSSSFSCGSSRSVRFA 507
VAPDSCAPCQPRSSSFSCGSSRSVRFA
Sbjct: 481 VAPDSCAPCQPRSSSFSCGSSRSVRFA 507
>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 486
Score = 789 bits (2038), Expect = 0.0
Identities = 408/492 (82%), Positives = 436/492 (88%), Gaps = 24/492 (4%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNL 59
M+C SY CG R FS SA P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 1 MTCGSY-----CG-GRAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-- 51
Query: 60 GSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 119
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
Sbjct: 52 ---------GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
Query: 120 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETL 179
KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETL
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETL 162
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRK
Sbjct: 163 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRK 222
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
SDLEANVEAL++E FLRRLYEEEIRVLQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQY
Sbjct: 223 SDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQY 282
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
DD+ +RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ
Sbjct: 283 DDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQ 342
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
+KLEAAVA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIE
Sbjct: 343 NSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIE 402
Query: 420 IATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTP---GRQITSGPSAIGG 476
IATYRRLLEGEE RLCEGVGSVNVCVSSSRGGV CG L STT +++S PS
Sbjct: 403 IATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPS--NS 460
Query: 477 SITVVAPDSCAP 488
++ V ++CAP
Sbjct: 461 NVVVGTTNACAP 472
>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 486
Score = 789 bits (2038), Expect = 0.0
Identities = 408/492 (82%), Positives = 436/492 (88%), Gaps = 24/492 (4%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNL 59
M+C SY CG R FS SA P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 1 MTCGSY-----CG-GRAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-- 51
Query: 60 GSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 119
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
Sbjct: 52 ---------GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
Query: 120 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETL 179
KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETL
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETL 162
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRK
Sbjct: 163 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRK 222
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
SDLEANVEAL++E FLRRLYEEEIRVLQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQY
Sbjct: 223 SDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQY 282
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
DD+ +RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ
Sbjct: 283 DDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQ 342
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
+KLEAAVA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIE
Sbjct: 343 NSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIE 402
Query: 420 IATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTP---GRQITSGPSAIGG 476
IATYRRLLEGEE RLCEGVGSVNVCVSSSRGGV CG L STT +++S PS
Sbjct: 403 IATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPS--NS 460
Query: 477 SITVVAPDSCAP 488
++ V ++CAP
Sbjct: 461 NVVVGTTNACAP 472
>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
sapiens]
Length = 486
Score = 789 bits (2038), Expect = 0.0
Identities = 408/492 (82%), Positives = 436/492 (88%), Gaps = 24/492 (4%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNL 59
M+C SY CG R FS SA P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 1 MTCGSY-----CG-GRAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-- 51
Query: 60 GSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 119
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
Sbjct: 52 ---------GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
Query: 120 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETL 179
KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETL
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETL 162
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRK
Sbjct: 163 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRK 222
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
SDLEANVEAL++E FLRRLYEEEIRVLQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQY
Sbjct: 223 SDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQY 282
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
DD+ +RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ
Sbjct: 283 DDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQ 342
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
+KLEAAVA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIE
Sbjct: 343 NSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIE 402
Query: 420 IATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTP---GRQITSGPSAIGG 476
IATYRRLLEGEE RLCEGVGSVNVCVSSSRGGV CG L STT +++S PS
Sbjct: 403 IATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPS--NS 460
Query: 477 SITVVAPDSCAP 488
++ V ++CAP
Sbjct: 461 NVVVGTTNACAP 472
>gi|14318422 keratin 86 [Homo sapiens]
Length = 486
Score = 789 bits (2038), Expect = 0.0
Identities = 408/492 (82%), Positives = 436/492 (88%), Gaps = 24/492 (4%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNL 59
M+C SY CG R FS SA P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 1 MTCGSY-----CG-GRAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-- 51
Query: 60 GSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 119
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
Sbjct: 52 ---------GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
Query: 120 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETL 179
KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETL
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETL 162
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRK
Sbjct: 163 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRK 222
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
SDLEANVEAL++E FLRRLYEEEIRVLQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQY
Sbjct: 223 SDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQY 282
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
DD+ +RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ
Sbjct: 283 DDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQ 342
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
+KLEAAVA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIE
Sbjct: 343 NSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIE 402
Query: 420 IATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTP---GRQITSGPSAIGG 476
IATYRRLLEGEE RLCEGVGSVNVCVSSSRGGV CG L STT +++S PS
Sbjct: 403 IATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPS--NS 460
Query: 477 SITVVAPDSCAP 488
++ V ++CAP
Sbjct: 461 NVVVGTTNACAP 472
>gi|169790841 keratin 83 [Homo sapiens]
Length = 493
Score = 783 bits (2023), Expect = 0.0
Identities = 408/500 (81%), Positives = 438/500 (87%), Gaps = 20/500 (4%)
Query: 9 SSGCGVTR-NFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLGSCGPRI 66
S GCG NFS SA P+ +RCCI+AAPYRG+SCYRGLTG FGS S+C
Sbjct: 7 SIGCGFRPGNFSCVSACGPRP-SRCCITAAPYRGISCYRGLTGGFGSHSVC--------- 56
Query: 67 AVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 126
GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ
Sbjct: 57 --GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114
Query: 127 IKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECV 186
IKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF+GYIETLRREAECV
Sbjct: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174
Query: 187 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANV 246
EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFV LKKDVDCAYLRKSDLEANV
Sbjct: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234
Query: 247 EALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRS 306
EAL++E FLRRLYEEEIR+LQ+HISDTSV+VK+DNSRDLNMDCI+AEIKAQYDD+A+RS
Sbjct: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294
Query: 307 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAA 366
RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ +KLEAA
Sbjct: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354
Query: 367 VAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 426
VA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL
Sbjct: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414
Query: 427 LEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQIT-SGPSAIGGSITVVAPDS 485
LEGEE RLCEGV +VNVCVSSSRGGV CG L S + R +T S SA VV+
Sbjct: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGS--RPVTGSVCSAPCNGNLVVSTGL 472
Query: 486 CAPCQPRSSSF---SCGSSR 502
C PC +++ SCG R
Sbjct: 473 CKPCGQLNTTCGGGSCGQGR 492
>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
Length = 505
Score = 778 bits (2010), Expect = 0.0
Identities = 401/487 (82%), Positives = 430/487 (88%), Gaps = 16/487 (3%)
Query: 16 RNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLGSCGPRIAVGGFRAG 74
R FS SA P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C GGFRAG
Sbjct: 10 RAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-----------GGFRAG 57
Query: 75 SCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 134
SCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF
Sbjct: 58 SCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 117
Query: 135 AAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLA 194
AAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETLRREAECVEADSGRLA
Sbjct: 118 AAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLA 177
Query: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254
SELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRKSDLEANVEAL++E
Sbjct: 178 SELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEID 237
Query: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314
FLRRLYEEEI +LQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQYDD+ +RSRAEAESWY
Sbjct: 238 FLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWY 297
Query: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374
RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ +KLEAAVA++EQQG
Sbjct: 298 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQG 357
Query: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434
EAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEGEE RL
Sbjct: 358 EAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL 417
Query: 435 CEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQIT-SGPSAIGGSITVVAPDSCAPCQPRS 493
CEG+G+VNVCVSSSRGGV CG L S + R +T S SA V+ CAPC +
Sbjct: 418 CEGIGAVNVCVSSSRGGVVCGDLCVSGS--RPVTGSVCSAPCNGNVAVSTGLCAPCGQLN 475
Query: 494 SSFSCGS 500
++ GS
Sbjct: 476 TTCGGGS 482
>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
Length = 600
Score = 579 bits (1492), Expect = e-165
Identities = 321/535 (60%), Positives = 378/535 (70%), Gaps = 50/535 (9%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG 60
MSCRSYR+SSG V NFSSCSA+ P+ NR ++ +RGL FGSRS+ G
Sbjct: 1 MSCRSYRVSSGHRVG-NFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFG 59
Query: 61 SCGPRIAVGGFR---------------------------AGSC----------------G 77
S PRIA G R A SC G
Sbjct: 60 SYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGG 119
Query: 78 RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 137
FGYR GGV P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+F
Sbjct: 120 PGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASF 179
Query: 138 IDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLASEL 197
IDKVRFLEQQNKLLETKW F Q Q+C SNLEPLF YI LRR+ E + +D RL +E
Sbjct: 180 IDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAER 239
Query: 198 NHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLR 257
NH+Q+VLEG+KKKYEEEV RA AENEFV LKKDVD A++ KSDLEANV+ L +E FL+
Sbjct: 240 NHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLK 299
Query: 258 RLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSK 317
LY EEI++LQ+HIS+TSVIVKMDNSRDLN+D IIAE+KAQY++VA RSRA+AE+WY++K
Sbjct: 300 TLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTK 359
Query: 318 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAA 377
EEM+ T +H + LR + EINEL R+IQRL AEIE+AK QRAKLEAAVAEAEQQGEA
Sbjct: 360 YEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEAT 419
Query: 378 LSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEG 437
LSDA+CKLA+LE ALQ+AKQDMA L EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEG
Sbjct: 420 LSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEG 479
Query: 438 VGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSITVVAPD----SCAP 488
VG VN+ VSSSRGG+ CG G ++ G GS +V A SC P
Sbjct: 480 VGPVNISVSSSRGGLVCG--PEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGP 532
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 566 bits (1459), Expect = e-161
Identities = 307/505 (60%), Positives = 368/505 (72%), Gaps = 12/505 (2%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYR--GVSCYRGLTGFGSRSLCN 58
MS S++ S CG +++FSS SAV P+ +S P R G R L GSRSLCN
Sbjct: 1 MSYHSFQPGSRCG-SQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCN 59
Query: 59 LGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 118
+G PR+A R G FGYR G CGPS CIT V++NESLL PL LEIDP Q
Sbjct: 60 VGFGRPRVAS---RCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQR 115
Query: 119 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIET 178
VK++EKEQIK LN+RFA+FI+KVRFLEQ+NKLLETKW F Q QRCC++N+EP+F GYI
Sbjct: 116 VKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISA 175
Query: 179 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLR 238
LRR+ +CV D RL SEL +Q LEGYKKKYEEE++LR ENEFV LKKDVD A+L
Sbjct: 176 LRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLM 235
Query: 239 KSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQ 298
K+DLE N EALV+E FL+ LYEEEI +LQ+ IS+TSVIVKMDNSR+L++D IIAEIKAQ
Sbjct: 236 KADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQ 295
Query: 299 YDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKC 358
YDD+ASRS+AEAE+WY+ + EE++ T H + LR K EI E+N++IQRL E EN K
Sbjct: 296 YDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKA 355
Query: 359 QRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDI 418
QR KLE A+AEAEQQGEAAL+DA+CKLA LE ALQKAKQDMACLLKEYQEVMNSKLGLDI
Sbjct: 356 QRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDI 415
Query: 419 EIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSI 478
EIATYRRLLEGEEHRLCEG+G VN+ VSSS+G ST +++G G
Sbjct: 416 EIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTP---VLSTGVLRSNGGC 472
Query: 479 TVVAP-DSCAPCQPRSSSFSCGSSR 502
++V + PC+P+ SCGS R
Sbjct: 473 SIVGTGELYVPCEPQ-GLLSCGSGR 496
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 453 bits (1166), Expect = e-127
Identities = 264/523 (50%), Positives = 345/523 (65%), Gaps = 48/523 (9%)
Query: 4 RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGL-------TGFGSRSL 56
R I+ G R FS+ SA+ P G S + R + GL FGSRSL
Sbjct: 3 RQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSL 62
Query: 57 CNLGSCGPRIAVGGF----RAGSCGRS---------FGYRSG---GVCGPS-PPC----I 95
NLG R+++ G R+G GR+ FGY G G GPS P C I
Sbjct: 63 YNLGGA-KRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGI 121
Query: 96 TTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKW 155
V+VN+SLLTPL+L+IDP Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETKW
Sbjct: 122 QEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 181
Query: 156 QFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEE 213
Q Q R NLEPLF Y LRR+ E + + GRL +EL ++Q+V+E +K +YE+
Sbjct: 182 ALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYED 241
Query: 214 EVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISD 273
E+ R AENEFV LKKDVD AY+ K +LEA V++L EE +F+ +++ E+ LQ + D
Sbjct: 242 EINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGD 301
Query: 274 TSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLR 333
TSV++ MDN+R+L++D IIAE+KAQY+D+A+RSRAEAESWY++K EE++ T RHG+ LR
Sbjct: 302 TSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLR 361
Query: 334 RTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQ 393
TK+EI+E+NRMIQRL AEI++ K Q + L+ A+A+AEQ+GE AL DAR KL +LE ALQ
Sbjct: 362 NTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQ 421
Query: 394 KAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCV------- 445
KAKQDMA LL+EYQE+MN KL LD+EIATYR+LLEGEE RL EGV VN+ V
Sbjct: 422 KAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSS 481
Query: 446 ----SSSRGGVSCG-----GLSYSTTPGRQITSGPSAIGGSIT 479
SS GG + G G S++T+ G + +G G S T
Sbjct: 482 GYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSAT 524
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 452 bits (1164), Expect = e-127
Identities = 266/550 (48%), Positives = 353/550 (64%), Gaps = 77/550 (14%)
Query: 4 RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRG----------VSCYRGLTGFGS 53
R +S G +R+FS+ SA+ P S + G ++ G+ G+GS
Sbjct: 3 RQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGS 62
Query: 54 RSLCNLGSCGPRIAV----GGFR-------------AGSCGRSFGYRSG----------- 85
RSL NLG RI++ G FR G G FG+ G
Sbjct: 63 RSLYNLGG-SKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121
Query: 86 ----GVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAA 136
G GP P C I V+VN+SLLTPLNL+IDP+ Q V+ EE+EQIK+LN++FA+
Sbjct: 122 GFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181
Query: 137 FIDKVRFLEQQNKLLETKWQFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLA 194
FIDKVRFLEQQNK+L+TKW Q Q + NLEPLF YI LRR+ + + + GRL
Sbjct: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241
Query: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254
SEL ++Q+++E +K KYE+E+ R TAENEFV+LKKDVD AY+ K +LEA V+AL++E +
Sbjct: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301
Query: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314
F++ ++ E+ +Q H+SDTSV++ MDN+R+L++D IIAE+KAQY+++A+RSR EAESWY
Sbjct: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361
Query: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374
++K EE++ T RHG+ LR TK EI+E+NRMIQRL AEI+N K Q A L+ A+A+AEQ+G
Sbjct: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421
Query: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434
E AL DAR KLAELE ALQKAKQDMA LL+EYQE+MN+KL LD+EIATYR+LLEGEE RL
Sbjct: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481
Query: 435 C-EGVGSVNVCVSSSR-------------------GGVSCGGLS-------YSTTPGRQI 467
EGVG VN+ V +S GG GGL+ YS++ G
Sbjct: 482 SGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVG 541
Query: 468 TSGPSAIGGS 477
G ++GGS
Sbjct: 542 LGGGLSVGGS 551
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 449 bits (1156), Expect = e-126
Identities = 273/553 (49%), Positives = 346/553 (62%), Gaps = 76/553 (13%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYR-----GVSCYRGLTGFGSRS 55
M+ S I S R FS+ SA P S + R G+ G GFGSRS
Sbjct: 1 MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRS 60
Query: 56 LCNLGSCGPRIAVGGFRAGSCGRSFGYRS------------------------------- 84
L LG RI++GG GSC S GY S
Sbjct: 61 LYGLGG-SKRISIGG---GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA 116
Query: 85 ---GGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAA 136
GG GP P C I V+VN+SLLTPLNL+IDP Q V+ EE+EQIK+LN++FA+
Sbjct: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFAS 176
Query: 137 FIDKVRFLEQQNKLLETKWQFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLA 194
FIDKVRFLEQQNK+LETKW Q Q + NLEPLF YI LRR+ + + + GRL
Sbjct: 177 FIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236
Query: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254
SEL +Q+++E +K KYE+E+ R AENEFV LKKDVD AY+ K +L+A + L +E +
Sbjct: 237 SELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296
Query: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314
FLR LY+ E+ +Q HISDTSV++ MDN+R+L++D IIAE+KAQY+++A RSRAEAESWY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356
Query: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374
++K EE++ T RHG+ LR TK+EI E+NRMIQRL +EI++ K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416
Query: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434
E AL DA+ KL LE ALQKAKQD+A LLKEYQE+MN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476
Query: 435 -CEGVGSVNV-----CVSSSRGGVS--------CGGLSY------------STTPGRQIT 468
EGVG VN+ VSS GG S GG SY S++ GR I
Sbjct: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIG 536
Query: 469 SGPSAIGGSITVV 481
G S++GG + +
Sbjct: 537 GGLSSVGGGSSTI 549
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 448 bits (1152), Expect = e-126
Identities = 280/562 (49%), Positives = 349/562 (62%), Gaps = 69/562 (12%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNR--CCISAAPYRGVSCYRGL---TGFGSRS 55
M+ S I S R FS+ SA P IS + RG G GFGSRS
Sbjct: 1 MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRS 60
Query: 56 LCNLGSCGPRIAVGGFRAGSCGRSFGYRS------------------------------- 84
L LG RI++GG GSC S GY S
Sbjct: 61 LYGLGG-SKRISIGG---GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA 116
Query: 85 ---GGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAA 136
GG GP P C I V+VN+SLLTPLNL+IDP Q V+ EE+EQIK+LN++FA+
Sbjct: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFAS 176
Query: 137 FIDKVRFLEQQNKLLETKWQFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLA 194
FIDKVRFLEQQNK+L+TKW Q Q + NLEPLF YI LRR+ + + + GRL
Sbjct: 177 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236
Query: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254
SEL ++Q+++E K KYE+E+ R AENEFV LKKDVD AY+ K +L+A + L +E +
Sbjct: 237 SELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296
Query: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314
FLR LY+ E+ +Q HISDTSV++ MDN+R+L++D IIAE+KAQY+++A RSRAEAESWY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356
Query: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374
++K EE++ T RHG+ LR TK+EI E+NRMIQRL +EI++ K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRG 416
Query: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434
E AL DA+ KL LE ALQKAKQD+A LLKEYQE+MN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476
Query: 435 -CEGVGSVNVCV-----SSSRGGVS--------CGGLSYSTTPGRQITSGPS-----AIG 475
EGVG VNV V SS GG S GG SYS G I G S AIG
Sbjct: 477 NGEGVGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIG 536
Query: 476 GSITVVAPDSCAPCQPRSSSFS 497
G ++ V S +SS S
Sbjct: 537 GGLSSVGGGSSTIKYTTTSSSS 558
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 445 bits (1144), Expect = e-125
Identities = 271/539 (50%), Positives = 340/539 (63%), Gaps = 64/539 (11%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNR--CCISAAPYRGVSCYRGL---TGFGSRS 55
M+ S I S R FS+ SA P IS + RG G GFGSRS
Sbjct: 1 MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRS 60
Query: 56 LCNLGSCGPRIAVGGFRAGSCGRSFGYRS------------------------------- 84
L LG RI++GG GSC S GY S
Sbjct: 61 LYGLGG-SKRISIGG---GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA 116
Query: 85 ---GGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAA 136
GG GP P C I V+VN+SLLTPLNL+IDP Q V+ EE+EQIK+LN++FA+
Sbjct: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFAS 176
Query: 137 FIDKVRFLEQQNKLLETKWQFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLA 194
FIDKVRFLEQQNK+L+TKW Q Q + NLEPLF YI LRR+ + + + GRL
Sbjct: 177 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLD 236
Query: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254
SEL ++Q+++E K KYE+E+ R AENEFV LKKDVD AY+ K +L+A + L +E +
Sbjct: 237 SELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296
Query: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314
FLR LY+ E+ +Q HISDTSV++ MDN+R+L++D IIAE+KAQY+++A RSRAEAESWY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356
Query: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374
++K EE++ T RHG+ LR TK+EI E+NRMIQRL +EI++ K Q A L+AA+A+AEQ+G
Sbjct: 357 QTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416
Query: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434
E AL DA+ KL LE ALQKAKQD+A LLKEYQE+MN KL LD+EIATYR+LLEGEE RL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476
Query: 435 -CEGVGSVNV-----CVSSSRGGVS--------CGGLSYSTTPGRQITSGPSAIGGSIT 479
EGVG VN+ VSS GG S GG SYS G + G S+ G T
Sbjct: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAT 535
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 429 bits (1104), Expect = e-120
Identities = 237/431 (54%), Positives = 303/431 (70%), Gaps = 20/431 (4%)
Query: 50 GFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLN 109
G GS SL LG+ PR+AV G G I V++N+SLL PL
Sbjct: 33 GLGSSSLYGLGASRPRVAVRSAYGGPVGAG---------------IREVTINQSLLAPLR 77
Query: 110 LEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLE 169
L+ DP+ Q V+QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETKW Q Q+ +S+
Sbjct: 78 LDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRL 137
Query: 170 P-LFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVL 228
P +F I LR + E ++ D GRL +EL +Q+V+E +K KYE+E+ R AENEFVVL
Sbjct: 138 PDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVL 197
Query: 229 KKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNM 288
KKDVD AY+ K +LEA V+AL +E +FLR L E E+ LQ+ ISDTSV++ MDNSR L++
Sbjct: 198 KKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDL 257
Query: 289 DCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 348
D IIAE+KAQY+++A SRAEAE+WY++K E ++A +HG+ LR T+ EI+E+NR IQR
Sbjct: 258 DGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQR 317
Query: 349 LTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQE 408
L AEI+N K QRAKLEAA+AEAE++GE AL DAR K ELE ALQ+ KQDMA L+EYQE
Sbjct: 318 LQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQE 377
Query: 409 VMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCG---GLSYSTTPG 464
+M+ KL LDIEIATYR+LLEGEE RL +GVG+VN+ V +S GG S G GL+ T G
Sbjct: 378 LMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMG 437
Query: 465 RQITSGPSAIG 475
S S+ G
Sbjct: 438 SNALSFSSSAG 448
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 429 bits (1103), Expect = e-120
Identities = 237/437 (54%), Positives = 312/437 (71%), Gaps = 20/437 (4%)
Query: 34 ISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPP 93
+S + R S +G GSR + S R+ FR G G GY GG G
Sbjct: 12 VSTSGPRAFSSRSYTSGPGSRISSSSFS---RVGSSNFRGGLGG---GY--GGASGMGG- 62
Query: 94 CITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLET 153
IT V+VN+SLL+PL LE+DPN Q V+ +EKEQIK+LN++FA+FIDKVRFLEQQNK+LET
Sbjct: 63 -ITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLET 121
Query: 154 KWQFYQNQRCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEE 213
KW Q Q+ SN++ +F YI LRR+ E + + +L +EL ++Q ++E +K KYE+
Sbjct: 122 KWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYED 181
Query: 214 EVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISD 273
E+ R ENEFV++KKDVD AY+ K +LE+ +E L +E +FLR+LYEEEIR LQ+ ISD
Sbjct: 182 EINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISD 241
Query: 274 TSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLR 333
TSV++ MDNSR L+MD IIAE+KAQY+D+A+RSRAEAES Y+ K EE+++ +HG+ LR
Sbjct: 242 TSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLR 301
Query: 334 RTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQ 393
RTK EI+E+NR I RL AEIE K QRA LEAA+A+AEQ+GE A+ DA KL+ELE ALQ
Sbjct: 302 RTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQ 361
Query: 394 KAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNV---------- 443
+AKQDMA L+EYQE+MN KL LDIEIATYR+LLEGEE RL G+ ++++
Sbjct: 362 RAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAG 421
Query: 444 CVSSSRGGVSCGGLSYS 460
+SS+ GG++ GLSYS
Sbjct: 422 GLSSAYGGLTSPGLSYS 438
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 422 bits (1085), Expect = e-118
Identities = 245/495 (49%), Positives = 332/495 (67%), Gaps = 29/495 (5%)
Query: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNL-GSCGPRIAVGGF 71
G R FS SA+ G R S+ G + GFGSRSL NL G+ ++V G
Sbjct: 84 GGPRGFSCGSAIVGG-GKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142
Query: 72 RAGSC------------GRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDP 114
R G+C G FG G GP P C I V++N+SLLTPL++EIDP
Sbjct: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDP 202
Query: 115 NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCES--NLEPLF 172
Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETKW Q Q S NLEPLF
Sbjct: 203 EIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLF 262
Query: 173 SGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDV 232
Y+ LR++ + + D GRL SEL +Q+ +E +K KYEEE+ R AEN+FVVLKKDV
Sbjct: 263 ETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDV 322
Query: 233 DCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCII 292
D AYL K +LEA V++L +E +FL+ LY+ E+ +Q H+SDTSV++ MDN+R+L++D II
Sbjct: 323 DAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSII 382
Query: 293 AEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 352
AE++AQY+++A RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE
Sbjct: 383 AEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAE 442
Query: 353 IENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNS 412
IEN K Q L+ +VA+AEQ+GE AL DA K ELE ALQ+AK+++A +L+EYQE+M+
Sbjct: 443 IENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSV 502
Query: 413 KLGLDIEIATYRRLLEGEEHRL---CEGVGSVNVCV-SSSRGGVSCG---GLSYSTTPGR 465
KL LDIEIATYR+LLEGEE+R+ C+ S++V S+S GG+S G G + + G
Sbjct: 503 KLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSSGF 562
Query: 466 QITSGPS-AIGGSIT 479
SG GGS++
Sbjct: 563 GSGSGSGFGFGGSVS 577
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 422 bits (1084), Expect = e-118
Identities = 250/519 (48%), Positives = 342/519 (65%), Gaps = 37/519 (7%)
Query: 4 RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLG-- 60
R + SG FS CSAV +G S++ YR +GL+G F SRSL +LG
Sbjct: 3 RQFTYKSGAAAKGGFSGCSAVL--SGG----SSSSYRAGG--KGLSGGFSSRSLYSLGGA 54
Query: 61 -SCGPRIAVGGFRAGSCGRSFGYRSG------------GVCGPS---PPCITTVSVNESL 104
S +A G AG G G SG VC PS P I V++N+SL
Sbjct: 55 RSISFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVC-PSLCPPGGIHQVTINKSL 113
Query: 105 LTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQR 162
L PLN+E+DP Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETKW+ Q +
Sbjct: 114 LAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 173
Query: 163 CCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAE 222
C++NLEP+ GYI LR++ E + D RL SEL V+EV+E YKK+YEEE+ R TAE
Sbjct: 174 NCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAE 233
Query: 223 NEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDN 282
NEFVVLKKDVD AY K +L+A V+AL E F + LYE E +Q+HISDTS+I+ MDN
Sbjct: 234 NEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDN 293
Query: 283 SRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 342
+R+L++D IIAE++AQY+++A +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL
Sbjct: 294 NRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISEL 353
Query: 343 NRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACL 402
R+IQRL +EIE+ K Q A LE A+A+AEQ+G+ AL DAR KL ELEGALQ+AK+++A +
Sbjct: 354 TRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARM 413
Query: 403 LKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCV-SSSRGGVSCGGLSYS 460
L+EYQE+++ KL LDIEIATYR+LLEGEE R+ E SV++ V +SS G++ G +
Sbjct: 414 LREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFG 473
Query: 461 TTPGRQITSGPSAIGGSITVVAPDSCAP----CQPRSSS 495
+ PS++ G +++ P C C PR +
Sbjct: 474 FSNAGTYGYWPSSVSGGYSML-PGGCVTGSGNCSPRGEA 511
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 418 bits (1075), Expect = e-117
Identities = 235/449 (52%), Positives = 304/449 (67%), Gaps = 17/449 (3%)
Query: 39 YRGVSCYRGLTGFGSRSLCNLGSCGPRIAVGGFRA-GSCGRSFGYRSGGVCGPSPPCITT 97
+ G + G GFG G G GGF GS G G+ GG P I
Sbjct: 119 FGGAGGFGGAGGFGGAG--GFGGPGGFGGSGGFGGPGSLGSPGGFGPGGF----PGGIQE 172
Query: 98 VSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQF 157
V++N+SLL PLN+EIDP VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETKW
Sbjct: 173 VTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNL 232
Query: 158 YQNQRCCE----SNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEE 213
Q Q +NLEPLF +I LR + + + GRL SEL ++++++E +KKKYE+
Sbjct: 233 LQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYED 292
Query: 214 EVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISD 273
E+ R AENEFV LKKDVD AY+ K +L+A V+AL++E FLR LY+ E+ +Q+HISD
Sbjct: 293 EINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISD 352
Query: 274 TSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLR 333
TSV++ MDN+R L++D IIAE++AQY+D+A RS+AEAE+ Y++K E++ T RHG+ LR
Sbjct: 353 TSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLR 412
Query: 334 RTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQ 393
TK EI ELNRMIQRL AEIE K Q A L+ A+AEAEQ GE AL DA KL EL+ ALQ
Sbjct: 413 NTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQ 472
Query: 394 KAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL---CEGVGSVNVCVSSSRG 450
+AK D+A LL++YQE+MN KL LD+EIATYR+LLEGEE+R+ C S++V VSSS
Sbjct: 473 QAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISV-VSSSTT 531
Query: 451 GVSCGGL--SYSTTPGRQITSGPSAIGGS 477
S GG Y G + G SA GGS
Sbjct: 532 SASAGGYGGGYGGGMGGGLGGGFSAGGGS 560
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 13/86 (15%)
Query: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCY---RGLTGFGSRSLCNLG---SCGPRI 66
G ++ FS SAV + C++ + G Y G GFGSRSL NLG S +
Sbjct: 11 GGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISV 70
Query: 67 AVGGFRAG-------SCGRSFGYRSG 85
A GG RAG SC + GY G
Sbjct: 71 AAGGSRAGGFGGGRSSCAFAGGYGGG 96
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 416 bits (1070), Expect = e-116
Identities = 235/495 (47%), Positives = 325/495 (65%), Gaps = 25/495 (5%)
Query: 4 RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCG 63
R + SG FS CSAV +G A +G+S GFGSRSL +LG
Sbjct: 3 RQFTCKSGAAAKGGFSGCSAVL--SGGSSSSFRAGSKGLS-----GGFGSRSLYSLGGVR 55
Query: 64 P-RIAVGGFRAGSCGRSFGYRSG------GVCGPSPPCITT--------VSVNESLLTPL 108
+A G ++G G G SG G P C T V+VNESLL PL
Sbjct: 56 SLNVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPL 115
Query: 109 NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCES 166
N+E+DP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW+ Q + C++
Sbjct: 116 NVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 175
Query: 167 NLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFV 226
NLEP+ GYI LR++ E + D RL SEL +V++V+E YKK+YEEE+ R AENEFV
Sbjct: 176 NLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFV 235
Query: 227 VLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDL 286
+LKKDVD AY K +L+A VE++ +E F R L+E EI +Q+HISD SVI+ MDN+R+L
Sbjct: 236 LLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNL 295
Query: 287 NMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 346
++D II E++ QY+++A +S+AEAE+ Y++K +E++ RHG+ L+ TK EI+EL R+I
Sbjct: 296 DLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLI 355
Query: 347 QRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEY 406
QR+ +EIEN K Q + LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EY
Sbjct: 356 QRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREY 415
Query: 407 QEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYSTTPGR 465
QE+M+ KL LD+EIATYR+LLE EE R+ E V++ + SS G S G S G
Sbjct: 416 QELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYGFRPSMVSGG 475
Query: 466 QITSGPSAIGGSITV 480
+ + + I G +V
Sbjct: 476 YVANSSNCISGVCSV 490
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 407 bits (1045), Expect = e-113
Identities = 231/483 (47%), Positives = 318/483 (65%), Gaps = 44/483 (9%)
Query: 41 GVSCYRGLTGFGSRSLCNLGS--------CGPRI---AVGGFRAGS---CGRSFGYRSGG 86
G C G GFGSRSL NLG G + A+GGF GS G+ G ++ G
Sbjct: 47 GAHCGPGTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFG 106
Query: 87 VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 146
P P I V+VN+SLLTPL++EIDP Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 107 PACP-PGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
Query: 147 QNKLLETKWQFYQNQR----CCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQE 202
QNK+LETKW Q Q +NLEPLF Y+ ++R + ++++ GRL SEL +VQ+
Sbjct: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
Query: 203 VLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEE 262
++E +K KYE+E+ AENEFVVLKKDVD AY+ + DL V L +E FL++LYE
Sbjct: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
Query: 263 EIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMK 322
E+ +Q H+S+T+V++ MDN+R+L++D IIAE+KAQY+ +A RSRAEAE+WY++K EE++
Sbjct: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
Query: 323 ATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDAR 382
T +HG+ LR TK EI EL R IQRL E + AK Q +L+ A+AEAEQ+GE AL DA+
Sbjct: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
Query: 383 CKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL---CEGVG 439
KL +L+ AL +AK+D+ LL++YQE+MN KL LD+EIATYR+LLE EE R+ C
Sbjct: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
Query: 440 SVNVCVSSSR----------GGVSCGG------------LSYSTTPGRQITSGPSAIGGS 477
S++V +S+ GG+S GG + YST G +++G S + +
Sbjct: 466 SISVTGNSTTVCGGGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSILRKT 525
Query: 478 ITV 480
TV
Sbjct: 526 TTV 528
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 406 bits (1044), Expect = e-113
Identities = 229/462 (49%), Positives = 316/462 (68%), Gaps = 22/462 (4%)
Query: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAV---- 68
G FS CSAV S+A +R + +G FGS+SL LG G R
Sbjct: 11 GERLGFSGCSAVL---SGGIGSSSASFR--ARVKGSASFGSKSLSCLG--GSRSLALSAA 63
Query: 69 ----GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQ 121
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+
Sbjct: 64 ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRA 123
Query: 122 EEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETL 179
+E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW Q + C NLEP++ GYI L
Sbjct: 124 QEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNL 183
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
+++ E + D RL SEL ++Q+++E YKK+YE E+ R AENEFVVLKKDVD AY+ K
Sbjct: 184 QKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNK 243
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
+L+A V++L +E F + LYE EI +Q+HISDTS+++ MDN+RDL++D IIAE++AQY
Sbjct: 244 VELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQY 303
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
+++A +S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +EI N K Q
Sbjct: 304 EEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQ 363
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
A LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EYQE+++ KL LD+E
Sbjct: 364 CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDME 423
Query: 420 IATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYS 460
IATYR+LLE EE R+ E SV++ V SS GG +S
Sbjct: 424 IATYRKLLESEECRMSGEYPNSVSISVISST-NAGAGGAGFS 464
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 406 bits (1044), Expect = e-113
Identities = 229/462 (49%), Positives = 316/462 (68%), Gaps = 22/462 (4%)
Query: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAV---- 68
G FS CSAV S+A +R + +G FGS+SL LG G R
Sbjct: 11 GERLGFSGCSAVL---SGGIGSSSASFR--ARVKGSASFGSKSLSCLG--GSRSLALSAA 63
Query: 69 ----GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQ 121
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+
Sbjct: 64 ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRA 123
Query: 122 EEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETL 179
+E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW Q + C NLEP++ GYI L
Sbjct: 124 QEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNL 183
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
+++ E + D RL SEL ++Q+++E YKK+YE E+ R AENEFVVLKKDVD AY+ K
Sbjct: 184 QKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNK 243
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
+L+A V++L +E F + LYE EI +Q+HISDTS+++ MDN+RDL++D IIAE++AQY
Sbjct: 244 VELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQY 303
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
+++A +S+AEAE+ Y++K +E++ T +HG+ L+ TK EI+ELNR+IQR+ +EI N K Q
Sbjct: 304 EEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQ 363
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
A LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EYQE+++ KL LD+E
Sbjct: 364 CADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDME 423
Query: 420 IATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYS 460
IATYR+LLE EE R+ E SV++ V SS GG +S
Sbjct: 424 IATYRKLLESEECRMSGEYPNSVSISVISST-NAGAGGAGFS 464
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 403 bits (1035), Expect = e-112
Identities = 233/487 (47%), Positives = 318/487 (65%), Gaps = 36/487 (7%)
Query: 17 NFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGS---CGPRIAVGGFRA 73
NFS SAV P+ + S A Y G GFGSRSL +LG +A GG RA
Sbjct: 15 NFSVHSAVVPR---KAVGSLASYCAAGRGAG-AGFGSRSLYSLGGNRRISFNVAGGGVRA 70
Query: 74 GSCG--RSFGY---RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEID 113
G G GY R+ G G P C++ V+VN+SLL PLN+E+D
Sbjct: 71 GGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELD 130
Query: 114 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPL 171
P Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETKW+ Q + C+ NLEP+
Sbjct: 131 PEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPI 190
Query: 172 FSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKD 231
GYI LR++ E + D RL SEL +++++E YKK+YE E+ R TAENEFVVLKKD
Sbjct: 191 LEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKD 250
Query: 232 VDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCI 291
D AY K +L+A V++L +E FL+ LY+ EI +Q H S+TSVI+ MDN+RDL++D I
Sbjct: 251 ADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSI 310
Query: 292 IAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 351
IAE++ Y+++A +S+AEAE+ Y++K +E++ RHG+ L+ T+ E+ ELNR+IQR+
Sbjct: 311 IAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRC 370
Query: 352 EIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMN 411
EI N K QRA LE A+A+AEQ+G+ AL DA+ KL ELEGAL +AK+++A +L+EYQE+M+
Sbjct: 371 EIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMS 430
Query: 412 SKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSG 470
KL LD+EIATYR+LLEGEE R+ E SV++ V +S SY + G
Sbjct: 431 LKLALDMEIATYRKLLEGEECRMSGENPSSVSISV------ISSSSYSYHHPSSAGVDLG 484
Query: 471 PSAIGGS 477
SA+ GS
Sbjct: 485 ASAVAGS 491
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 401 bits (1030), Expect = e-112
Identities = 258/571 (45%), Positives = 332/571 (58%), Gaps = 81/571 (14%)
Query: 13 GVTRNFSSCSAVAPKTGNRCCI--SAAPYRGVSCYR-GLTGFGSRSLCNLGS---CGPRI 66
G ++ FS SAV + C+ S G +R G FGSRSL NLGS +
Sbjct: 12 GRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISV 71
Query: 67 AVGGFRAG-------SCGRSFGYR-----------------------------SGGVCGP 90
A G RAG SCG + GY +GG GP
Sbjct: 72 AAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGP 131
Query: 91 S-------------------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLN 131
P I V VN+SLL PLN+EIDP VK +E+EQIK+LN
Sbjct: 132 GVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLN 191
Query: 132 SRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCE--SNLEPLFSGYIETLRREAECVEAD 189
++FA+FIDKVRFLEQQNK+LETKW+ Q Q S+LEP F YI L ++ + + +
Sbjct: 192 NKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQLDSLLGE 251
Query: 190 SGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEAL 249
G L EL +Q+++E +KKKYE+E+ R AENEFV LKKDVD A++ K +L+A V++L
Sbjct: 252 RGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKVDSL 311
Query: 250 VEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAE 309
+E SFLR LYE E+ +Q+H SDTSV++ MDN+R L++ IIAE++AQY+++A RS++E
Sbjct: 312 TDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRSKSE 371
Query: 310 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAE 369
AE+ Y++K E++ T RHG+ LR TK EI ELNRMIQRL AEIEN K Q A L+ A+AE
Sbjct: 372 AEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTAIAE 431
Query: 370 AEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 429
AEQ+GE AL DA KL +L+ ALQKAK D+A LL++YQE+MN KL LD+EIATYR+LLEG
Sbjct: 432 AEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEG 491
Query: 430 EEHRLCEGVGSVNVCVS-------------SSR---GGVS-CGGLSYSTTPGRQITSGPS 472
EE R+ G VC+S SSR GGVS G Y +SG
Sbjct: 492 EECRM-SGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYG 550
Query: 473 AIGGSITVVAPDSCAPCQPRSSSFSCGSSRS 503
GGS + S R SS S SS S
Sbjct: 551 VSGGSGSGYGGVSSGSTGGRGSSGSYQSSSS 581
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 397 bits (1019), Expect = e-110
Identities = 212/410 (51%), Positives = 292/410 (71%), Gaps = 9/410 (2%)
Query: 50 GFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLN 109
G G GS G GGF G G +G VC P I V++N+SLL PLN
Sbjct: 113 GIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG----PVCPPGG--IQEVTINQSLLQPLN 166
Query: 110 LEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESN 167
+EIDP Q VK E+EQIKSLN++FA+FIDKVRFLEQQN++L+TKW+ Q + N
Sbjct: 167 VEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHN 226
Query: 168 LEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVV 227
LEP F +I LRR + +++D RL SEL ++Q+++E Y+ KYE+E+ R AENEFV
Sbjct: 227 LEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVT 286
Query: 228 LKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLN 287
+KKDVD AY+ K DL+A ++ L +E FL LY+ E+ +Q IS+T+VI+ MDN+R L+
Sbjct: 287 IKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLD 346
Query: 288 MDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQ 347
+D IIAE+KAQY+D+A +S+AEAES Y+SK EE++ T RHG+++R +K EI+ELNR+IQ
Sbjct: 347 LDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQ 406
Query: 348 RLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQ 407
RL +EI+N K Q + L+ ++++AEQ+GE AL DA+ KL +LE ALQ+AK+D+A LL++YQ
Sbjct: 407 RLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQ 466
Query: 408 EVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGG 456
E+MN+KL LD+EIATYR LLEGEE R+ E +V+V VS+S +S GG
Sbjct: 467 ELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGG 516
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 394 bits (1011), Expect = e-109
Identities = 250/559 (44%), Positives = 335/559 (59%), Gaps = 84/559 (15%)
Query: 1 MSCRSYRISSGCGVTRNFSSCSAVAP-----KTGNRCCISAAPYRGVSCYRGLTGFGSRS 55
+SC+S G G R FSS SAV T + C+S + G G GFGSRS
Sbjct: 5 ISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSR--HGGGGGGFGGGGFGSRS 62
Query: 56 LCNLG---SCGPRIAVGGFRAGSCGRSFGYRSGGVCGPS--------------------- 91
L LG S +A GG G+ G FG R GG G S
Sbjct: 63 LVGLGGTKSISISVAGGGGGFGAAG-GFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGG 121
Query: 92 -------------------------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 126
P I VSVN+SLL PLN+++DP Q VK +E+EQ
Sbjct: 122 RFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQ 181
Query: 127 IKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETLRREAE 184
IK+LN++FA+FIDKVRFLEQQN++L+TKW+ Q N NLEP+F GYI++L+R +
Sbjct: 182 IKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLD 241
Query: 185 CVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEA 244
+ A+ SELN++Q+++E YKKKYE+E+ R AEN+FV LKKDVD AY+ K +L++
Sbjct: 242 GLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQS 301
Query: 245 NVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVAS 304
V+ L +E FL+ LY+ EI + ++DT+VI+ MDNSR+L++D IIAE+KAQY+++A
Sbjct: 302 KVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQ 361
Query: 305 RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLE 364
RS+ EAE+ Y SK EE++ TV RHG++L+ K EI+ELNR+IQRL EI + K Q ++
Sbjct: 362 RSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQ 421
Query: 365 AAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYR 424
A+A+AEQ+GE AL DAR KL +LE ALQ+AK+D+A LL++YQE+MN KL LD+EIATYR
Sbjct: 422 DAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYR 481
Query: 425 RLLEGEEHRLCEGVGSVNVCV------------------------SSSRGGVSCGGLSYS 460
+LLEGEE R+ G S NV V SSS GG S G SY
Sbjct: 482 KLLEGEECRM-SGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG 540
Query: 461 TTPGRQITSGPSAIGGSIT 479
+ + + G S GGSI+
Sbjct: 541 SGGRQSGSRGGSGGGGSIS 559
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 367 bits (942), Expect = e-101
Identities = 230/516 (44%), Positives = 319/516 (61%), Gaps = 42/516 (8%)
Query: 10 SGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSC--GPRIA 67
S C R FS+ SA + ++ R RG RG GF SRSL + G C G R +
Sbjct: 4 SPCRAQRGFSARSACSARSRGRS-------RGGFSSRG--GFSSRSLNSFGGCLEGSRGS 54
Query: 68 VGGFRAGSCGRSFGYRSGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEE 123
G G G FG SGG +C P I V++N++LLTPL +EIDP Q V+ +E
Sbjct: 55 TWG-SGGRLGVRFGEWSGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQE 111
Query: 124 KEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRC--CESNLEPLFSGYIETLRR 181
++I++LN++FA+FIDKVRFLEQQNK+LETKW Q Q + LEP+F ++ LR+
Sbjct: 112 TQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRK 171
Query: 182 EAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSD 241
+ E ++ + G L +EL ++ E YK KYEEE RAT EN+FVVLKKDVD +L K +
Sbjct: 172 QLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKME 231
Query: 242 LEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDD 301
LE +EAL E FL+ L EEE+ LQ SDTSV++ MDN+R L+ II E++A+Y++
Sbjct: 232 LEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEE 291
Query: 302 VASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRA 361
+A S+AEAE+ Y++K +E++ + HG+ ++ TK +I++L++ IQRL ++ EN K Q A
Sbjct: 292 IARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNA 351
Query: 362 KLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIA 421
L+AA+ +AEQ+GE AL DA+ K+ ELE AL+ AKQ++A LL EYQE+ ++KL LD+EIA
Sbjct: 352 SLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIA 411
Query: 422 TYRRLLEGEEHRLCEGVGSVNVCVSSSRG------------GVSCGGLSYSTTPG----R 465
TYRRLLEGEE R+ G + V +SS G G +CG S +PG
Sbjct: 412 TYRRLLEGEECRM-SGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTS 470
Query: 466 QITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSS 501
+T G + I GS DSC+ S S GSS
Sbjct: 471 IVTGGSNIILGSGKDPVLDSCS-----VSGSSAGSS 501
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 363 bits (931), Expect = e-100
Identities = 205/446 (45%), Positives = 294/446 (65%), Gaps = 20/446 (4%)
Query: 47 GLTGFGSRSLCNLGSCGPRIAVGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 101
G+ GFG +GS G GGF G G + FG + G+ G P C I V++N
Sbjct: 87 GVGGFGGGRGFGVGSTG----AGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142
Query: 102 ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ-- 159
+SLL PL+LE+DP Q +K +E+EQI LN++FA+FIDKVRFLEQQN++L+TKW+ Q
Sbjct: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202
Query: 160 NQRCCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRA 219
N +NLEPL YI LRR+ + + A+ R +E+ +Q+V+E YK KYE+E+ R
Sbjct: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262
Query: 220 TAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVK 279
+EN+FVVLKKDVD AY+ K DLE+ V+ L E +FL+ L+ E+ +Q HISDT+VI+
Sbjct: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322
Query: 280 MDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 339
MDN+R L++D II ++ QY+ +A RS+ EAE+ Y++K +E++ T RHG+ L+ +K EI
Sbjct: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382
Query: 340 NELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDM 399
ELNR +QRL AEI N K Q ++++ +++AE++GE AL DA KL +LE ALQ++K+++
Sbjct: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442
Query: 400 ACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGS-VNVCVSSSR--------G 450
A LL++YQ ++ KL LD+EIATYR+LLEGEE R+ + S V++ V +S+ G
Sbjct: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAGG 502
Query: 451 GVSCGGLSYSTTPGRQITSGPSAIGG 476
G S G Y G G S GG
Sbjct: 503 GGSYGSGGYGGGSGGGYGGGRSYRGG 528
>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
Length = 469
Score = 349 bits (896), Expect = 3e-96
Identities = 209/462 (45%), Positives = 286/462 (61%), Gaps = 64/462 (13%)
Query: 13 GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSCGPRIAV---- 68
G FS CSAV S+A +R + +G FGS+SL LG G R
Sbjct: 11 GERLGFSGCSAVL---SGGIGSSSASFR--ARVKGSASFGSKSLSCLG--GSRSLALSAA 63
Query: 69 ----GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQ 121
GG G G +FG G PS P I V+VN+SLL PLN+E+DP Q V+
Sbjct: 64 ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRA 123
Query: 122 EEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETL 179
+E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW Q + C NLEP++ GYI L
Sbjct: 124 QEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNL 183
Query: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239
+++ E + D RL SEL ++Q+++E YKK+YE E+ R AENEFVVLKKDVD AY+ K
Sbjct: 184 QKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNK 243
Query: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299
+L+A V++L +E F + LYE EI +Q+HISDTS+++ MDN+RDL++D IIAE++AQY
Sbjct: 244 VELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQY 303
Query: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359
+++A +S+AEAE+ Y++KC
Sbjct: 304 EEIALKSKAEAETLYQTKC----------------------------------------- 322
Query: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
A LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EYQE+++ KL LD+E
Sbjct: 323 -ADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDME 381
Query: 420 IATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYS 460
IATYR+LLE EE R+ E SV++ V SS GG +S
Sbjct: 382 IATYRKLLESEECRMSGEYPNSVSISVISST-NAGAGGAGFS 422
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,584,107
Number of Sequences: 37866
Number of extensions: 837118
Number of successful extensions: 5610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 4001
Number of HSP's gapped (non-prelim): 1400
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.