Guide to the Human Genome
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Search of human proteins with 4504715

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2
[Homo sapiens]
         (644 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...  1276   0.0  
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...  1266   0.0  
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...  1214   0.0  
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]     960   0.0  
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]     876   0.0  
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s...   792   0.0  
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...   560   e-159
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]     490   e-138
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom...   318   1e-86
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo...   318   1e-86
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]               125   1e-28
gi|239753150 PREDICTED: similar to poly(A) binding protein, cyto...   124   2e-28
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                    115   2e-25
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]             114   4e-25
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                    114   4e-25
gi|55956788 nucleolin [Homo sapiens]                                  113   5e-25
gi|38201714 ELAV-like 1 [Homo sapiens]                                112   1e-24
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]              111   2e-24
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]              110   4e-24
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...   110   5e-24
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]            109   7e-24
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]                     108   1e-23
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]                     107   3e-23
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]                     107   3e-23
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]                     107   3e-23
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]                     107   3e-23
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...   106   6e-23
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo...   106   6e-23
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...   102   1e-21
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ...    94   5e-19

>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 1276 bits (3302), Expect = 0.0
 Identities = 644/644 (100%), Positives = 644/644 (100%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
           QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
Sbjct: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
           AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360

Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
           KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420

Query: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF 480
           PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF
Sbjct: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF 480

Query: 481 GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 540
           GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ
Sbjct: 481 GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 540

Query: 541 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 600
           APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS
Sbjct: 541 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 600

Query: 601 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
           ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Sbjct: 601 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 1266 bits (3275), Expect = 0.0
 Identities = 644/660 (97%), Positives = 644/660 (97%), Gaps = 16/660 (2%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
           QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
Sbjct: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
           AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360

Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
           KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420

Query: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPT------------ 468
           PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPT            
Sbjct: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTT 480

Query: 469 ----GSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYK 524
               GSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYK
Sbjct: 481 TQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYK 540

Query: 525 YASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHS 584
           YASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHS
Sbjct: 541 YASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHS 600

Query: 585 NLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
           NLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Sbjct: 601 NLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 660


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 1214 bits (3142), Expect = 0.0
 Identities = 620/644 (96%), Positives = 623/644 (96%), Gaps = 13/644 (2%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
           QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
Sbjct: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
           AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360

Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
           KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420

Query: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF 480
           PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTG+          
Sbjct: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGN---------- 470

Query: 481 GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 540
                A +GL  + Q  GVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ
Sbjct: 471 ---APASRGLPTTTQRVGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 527

Query: 541 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 600
           APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS
Sbjct: 528 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 587

Query: 601 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
           ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Sbjct: 588 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 631


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score =  960 bits (2481), Expect = 0.0
 Identities = 500/652 (76%), Positives = 553/652 (84%), Gaps = 30/652 (4%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MN +A SYPMASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1   MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
           QPADAERALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+FIKNLDKSIDNKALYDTFS
Sbjct: 61  QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
           AFGNILSCKVVCDENGSKGY FVHFETQEAA++AIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AELGA+AKEFTNVYIKNFGE++DDE LK+LF +FG  LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKRKFEQ+KQ+RI+RYQGVNLY+KN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDD IDDE+LRKEFSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360

Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGR 419
           KPLYVALAQRKEER+AHLTNQYMQR+A +RA+P N ++N +QPA   GYF+ A+PQ Q R
Sbjct: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR 419

Query: 420 PPYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAM 478
             YY P+Q+AQ+RP+PRW  QG RP  FQ MP AIR + PRP    + P  S+ P  +  
Sbjct: 420 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVM-- 477

Query: 479 DFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAP----RAVAPYKYASSVRSP-- 532
                  + Q + +        T+ Q + PR A AAAA     R V  YKYA+ VR+P  
Sbjct: 478 -------STQRVAN--------TSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQ 522

Query: 533 HPAIQP-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKIT 591
           H   QP +   QPAVHVQGQEPLTASMLA+APPQEQKQMLGERLFPLIQ MH  LAGKIT
Sbjct: 523 HLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKIT 582

Query: 592 GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAAT 643
           GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAH A KEAAQK  AV +AT
Sbjct: 583 GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQA-KEAAQK--AVNSAT 631


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score =  876 bits (2264), Expect = 0.0
 Identities = 464/647 (71%), Positives = 522/647 (80%), Gaps = 25/647 (3%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MN +  SYP ASLYVGDLH DVTEAMLYEKFSPAGP+LSIR+CRD+IT  S  YAYVNFQ
Sbjct: 1   MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
              DAE ALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+F+KNLDKSI+NKALYDT S
Sbjct: 61  HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 120

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
           AFGNILSC VVCDENGSKGY FVHFET EAA++AI+KMNGMLLN RKVFVG+FKSRKERE
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AELGA+AKEF NVYIKNFGE++DDE LK+LF +FG  LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKR FEQ+KQ+RI+RYQ VNLY+KN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKN 300

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDD IDDE+LRK FSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360

Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
           KPLYVALAQRKEER+A+LTN+YMQR+A +RA+P     NQ  P + GYF+ AVPQ Q   
Sbjct: 361 KPLYVALAQRKEERQAYLTNEYMQRMASVRAVP-----NQRAPPS-GYFMTAVPQTQNHA 414

Query: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMD 479
            YY P+Q+A++RP+PRW  QG RP  FQ  PSAIR   PR     + P  S+ P  +   
Sbjct: 415 AYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVM--- 471

Query: 480 FGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSP--HPAIQ 537
                + Q+    S Q+ G   A    A  AA A  A R V  YKYA+ VR+P  H   Q
Sbjct: 472 -----STQRVANTSTQTVGPRPA----AAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQ 522

Query: 538 P-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLE 596
           P +   Q AVHVQGQE LTAS LA+APPQ+QKQMLGERLFPLIQ MH  LAGKITGMLLE
Sbjct: 523 PQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLE 582

Query: 597 IDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAAT 643
           IDNSELL+MLESPESLRSKVDEAVAVLQAH A KEA QK  AV +AT
Sbjct: 583 IDNSELLYMLESPESLRSKVDEAVAVLQAHQA-KEATQK--AVNSAT 626


>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
           sapiens]
          Length = 614

 Score =  792 bits (2045), Expect = 0.0
 Identities = 408/632 (64%), Positives = 488/632 (77%), Gaps = 25/632 (3%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MNA+ S YP+ASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1   MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
           QPADAERALDTMNF+++KG+PIRIMWSQRDP LRKSGVGN+FIKNL+ SIDNKALYDTFS
Sbjct: 61  QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
            FGNILSCKV CDE+GS+G+ FVHFET EAA +AI  MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AELGA+A EFTN+Y+KN   +VD++ L++LFSQFGK LSVKVMRD +G S+ FGFV++EK
Sbjct: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HE+A KAV  MNGKE+SG++++ GRAQK+VERQ ELKR+FEQ+KQ+R+ RYQGVNLY+KN
Sbjct: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDD+IDD+KLRKEFSP+G ITSAKVM E G SKGFGFVCFSSPEEATKAVTEMNGRIVG+
Sbjct: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360

Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
           KPLYVALAQRKEERKA LTNQYMQR++ MR L +N +L  FQ  +  YF+PA+PQ   + 
Sbjct: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTL-SNPLLGSFQQPS-SYFLPAMPQPPAQA 418

Query: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMD 479
            YY    +   +P PRW  Q  RP     +   +    P   +  +    ++ P      
Sbjct: 419 AYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVP------ 472

Query: 480 FGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPL 539
                   + +  + +   + T  Q   P         R + P K +S+  S +      
Sbjct: 473 --------RTVPHTQRVANIGT--QTTGPSGVGCCTPGRPLLPCKCSSAAHSTY------ 516

Query: 540 QAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDN 599
           +  +PAVH+ GQEPLTASMLAAAP  EQKQM+GERL+PLI  +H+ LAGKITGMLLEIDN
Sbjct: 517 RVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDN 576

Query: 600 SELLHMLESPESLRSKVDEAVAVLQAHHAKKE 631
           SELL MLESPESL +K+DEAVAVLQAH A ++
Sbjct: 577 SELLLMLESPESLHAKIDEAVAVLQAHQAMEQ 608


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score =  560 bits (1444), Expect = e-159
 Identities = 279/370 (75%), Positives = 323/370 (87%), Gaps = 1/370 (0%)

Query: 1   MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
           MN AA  Y MASLYVGDLH+DVTE +L+ KFS  GPVLSIR+CRD +TRRSLGYAYVNF 
Sbjct: 1   MNVAAK-YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFL 59

Query: 61  QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
           Q ADA++ALDTMNFD+IKGK IR+MWSQRD  LR+SG+GNVFIKNLDKSIDNK LY+ FS
Sbjct: 60  QLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFS 119

Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
           AFG ILS KV+ D+ GSKGYAFVHF+ Q AAD+AIE+MNG LL   KVFVGRFK+RK+RE
Sbjct: 120 AFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179

Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
           AEL +KA EFTNVYIKNFG ++DDE LK++FS++GKTLSVKVM D +GKSKGFGFVS++ 
Sbjct: 180 AELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDS 239

Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
           HE A KAVEEMNG++I+G++IFVGRAQKKVERQAELK+ FEQLK+ERI   QGV LYIKN
Sbjct: 240 HEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKN 299

Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
           LDDTIDDEKLR EFS FGSI+  KVM E+G+SKGFG +CFSSPE+ATKA+TEMNGRI+GS
Sbjct: 300 LDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGS 359

Query: 361 KPLYVALAQR 370
           KPL +ALAQR
Sbjct: 360 KPLSIALAQR 369



 Score =  184 bits (468), Expect = 2e-46
 Identities = 111/293 (37%), Positives = 169/293 (57%), Gaps = 20/293 (6%)

Query: 95  KSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAAD 152
           K  + ++++ +L   +    L+  FS  G +LS ++  D+    S GYA+V+F     A 
Sbjct: 6   KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65

Query: 153 KAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFS 212
           KA++ MN  ++  + + +       +R+A L  +     NV+IKN  + +D+++L E FS
Sbjct: 66  KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119

Query: 213 QFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
            FGK LS KVM D  G SKG+ FV ++    A++A+EEMNGK + G  +FVGR + + +R
Sbjct: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178

Query: 273 QAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED-GR 331
           +AEL+ K  +            N+YIKN    +DDE+L+  FS +G   S KVM +  G+
Sbjct: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228

Query: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQ 384
           SKGFGFV F S E A KAV EMNGR +  + ++V  AQ+K ER+A L   + Q
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281



 Score =  103 bits (257), Expect = 5e-22
 Identities = 68/206 (33%), Positives = 114/206 (55%), Gaps = 26/206 (12%)

Query: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
           ++Y+ +   +V ++ L   FS  G  LS+++ RD    +S G+ +V++ +  DA KA++ 
Sbjct: 11  SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70

Query: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
           MN   I GK I +  +Q    R A L+R              G+ N++IKNLD +ID++ 
Sbjct: 71  MNFDIIKGKSIRLMWSQ----RDAYLRRS-------------GIGNVFIKNLDKSIDNKT 113

Query: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
           L + FS FG I S+KVM +D  SKG+ FV F +   A +A+ EMNG+++    ++V   +
Sbjct: 114 LYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173

Query: 370 RKEERKAHL-------TNQYMQRVAG 388
            +++R+A L       TN Y++   G
Sbjct: 174 NRKDREAELRSKASEFTNVYIKNFGG 199


>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
          Length = 382

 Score =  490 bits (1261), Expect = e-138
 Identities = 243/365 (66%), Positives = 300/365 (82%), Gaps = 1/365 (0%)

Query: 8   YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAER 67
           Y  A+LYVGDL  DVTE MLY+KF PAGP+   R+CRD +TR  LGY YVNF+ PADAE 
Sbjct: 15  YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74

Query: 68  ALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILS 127
           AL+TMNFD+I GKP R+MWSQ D  LRKSGVGN+FIKNLDKSIDN+AL+  FSAFGNILS
Sbjct: 75  ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134

Query: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
           CKVVCD+NGSKGYA+VHF++  AA++AI  MNG+ LN+R+V+VGRFK  +ER AE+  + 
Sbjct: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194

Query: 188 K-EFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
           +  FTNV++KN G+++DDE LKELF ++G T SVKV+RD +GKSKGFGFV YE HE A K
Sbjct: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254

Query: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTID 306
           AV +++GK I GK+++VGRAQKK+ER AEL+R+FE+L+ +  SR  GV +YIKNLD+TI+
Sbjct: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314

Query: 307 DEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVA 366
           DEKL++EFS FGSI+ AKVM+E G+ KGFG VCFSS EEATKAV EMNGRIVGSKPL+V 
Sbjct: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374

Query: 367 LAQRK 371
           L Q +
Sbjct: 375 LGQAR 379



 Score =  153 bits (386), Expect = 5e-37
 Identities = 97/285 (34%), Positives = 155/285 (54%), Gaps = 19/285 (6%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
           +++ +LD  +    LY  F   G +   ++  D       GY +V+F     A+ A+  M
Sbjct: 20  LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79

Query: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTL 218
           N  L+N  K F   +    +R  + G       N++IKN  + +D+ +L  LFS FG  L
Sbjct: 80  NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133

Query: 219 SVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR 278
           S KV+ D NG SKG+ +V ++    AN+A+  MNG  ++ + ++VGR +   ER AE++ 
Sbjct: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192

Query: 279 KFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGF 337
           +          R    N+++KN+ D IDDEKL++ F  +G   S KV+ +  G+SKGFGF
Sbjct: 193 R---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243

Query: 338 VCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQY 382
           V + + E A KAV +++G+ +  K LYV  AQ+K ER A L  ++
Sbjct: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 50/183 (27%), Positives = 98/183 (53%), Gaps = 19/183 (10%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +++V ++  D+ +  L E F   GP  S++V RD  + +S G+ +V ++    A++A+  
Sbjct: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258

Query: 72  MNFDVIKGKPIRIMWSQRD-----------------PSLRKSGVGNVFIKNLDKSIDNKA 114
           ++   I GK + +  +Q+                     R  GV  ++IKNLD++I+++ 
Sbjct: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317

Query: 115 LYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK 174
           L + FS+FG+I   KV+ +    KG+  V F + E A KA+++MNG ++  + + V   +
Sbjct: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377

Query: 175 SRK 177
           +R+
Sbjct: 378 ARR 380



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 290 RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSK--GFGFVCFSSPEEAT 347
           +Y    LY+ +LD  + ++ L K+F P G +   ++  +       G+G+V F  P +A 
Sbjct: 14  KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73

Query: 348 KAVTEMNGRIVGSKPLYVALAQRKEE-RKAHLTNQYMQRV 386
            A+  MN  ++  KP  +  +Q  +  RK+ + N +++ +
Sbjct: 74  WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113


>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
           sapiens]
          Length = 200

 Score =  318 bits (814), Expect = 1e-86
 Identities = 151/197 (76%), Positives = 176/197 (89%)

Query: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           MASLYVGDLH +VTEAMLYEKFSPAGP+LSIR+CRD ITRRSLGYAYVN+QQP DA+RAL
Sbjct: 1   MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60

Query: 70  DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
           +T+NFDVIKG+P+RIMWSQRDPSLRKSGVGNVFIKNL K+IDNKALY+ FSAFGNILSCK
Sbjct: 61  ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120

Query: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
           V CDE G KGY FVHF+ QE+A++AI+ MNGM LN RK+FVGRFKS KEREAE GA A++
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180

Query: 190 FTNVYIKNFGEEVDDES 206
            T+  +K+F E+ D+E+
Sbjct: 181 STSADVKDFEEDTDEEA 197



 Score =  103 bits (257), Expect = 5e-22
 Identities = 62/180 (34%), Positives = 104/180 (57%), Gaps = 9/180 (5%)

Query: 98  VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAI 155
           + ++++ +L   +    LY+ FS  G ILS ++  D+    S GYA+V+++    A +A+
Sbjct: 1   MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60

Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
           E +N  ++  R V +       +R+  L  +     NV+IKN G+ +D+++L  +FS FG
Sbjct: 61  ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114

Query: 216 KTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAE 275
             LS KV  D  G  KG+GFV ++K E A +A++ MNG  ++ + IFVGR +   ER+AE
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 60/187 (32%), Positives = 100/187 (53%), Gaps = 19/187 (10%)

Query: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
           ++Y+ +   EV +  L E FS  G  LS+++ RD    +S G+ +V+Y++  DA +A+E 
Sbjct: 3   SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62

Query: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
           +N   I G+ + +  +Q+                 +   R  GV N++IKNL  TID++ 
Sbjct: 63  LNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVGNVFIKNLGKTIDNKA 105

Query: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
           L   FS FG+I S KV  ++   KG+GFV F   E A +A+  MNG  +  + ++V   +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165

Query: 370 RKEERKA 376
             +ER+A
Sbjct: 166 SHKEREA 172


>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
           sapiens]
          Length = 200

 Score =  318 bits (814), Expect = 1e-86
 Identities = 151/197 (76%), Positives = 176/197 (89%)

Query: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           MASLYVGDLH +VTEAMLYEKFSPAGP+LSIR+CRD ITRRSLGYAYVN+QQP DA+RAL
Sbjct: 1   MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60

Query: 70  DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
           +T+NFDVIKG+P+RIMWSQRDPSLRKSGVGNVFIKNL K+IDNKALY+ FSAFGNILSCK
Sbjct: 61  ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120

Query: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
           V CDE G KGY FVHF+ QE+A++AI+ MNGM LN RK+FVGRFKS KEREAE GA A++
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180

Query: 190 FTNVYIKNFGEEVDDES 206
            T+  +K+F E+ D+E+
Sbjct: 181 STSADVKDFEEDTDEEA 197



 Score =  103 bits (257), Expect = 5e-22
 Identities = 62/180 (34%), Positives = 104/180 (57%), Gaps = 9/180 (5%)

Query: 98  VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAI 155
           + ++++ +L   +    LY+ FS  G ILS ++  D+    S GYA+V+++    A +A+
Sbjct: 1   MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60

Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
           E +N  ++  R V +       +R+  L  +     NV+IKN G+ +D+++L  +FS FG
Sbjct: 61  ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114

Query: 216 KTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAE 275
             LS KV  D  G  KG+GFV ++K E A +A++ MNG  ++ + IFVGR +   ER+AE
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 60/187 (32%), Positives = 100/187 (53%), Gaps = 19/187 (10%)

Query: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
           ++Y+ +   EV +  L E FS  G  LS+++ RD    +S G+ +V+Y++  DA +A+E 
Sbjct: 3   SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62

Query: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
           +N   I G+ + +  +Q+                 +   R  GV N++IKNL  TID++ 
Sbjct: 63  LNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVGNVFIKNLGKTIDNKA 105

Query: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
           L   FS FG+I S KV  ++   KG+GFV F   E A +A+  MNG  +  + ++V   +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165

Query: 370 RKEERKA 376
             +ER+A
Sbjct: 166 SHKEREA 172


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score =  125 bits (314), Expect = 1e-28
 Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 7/183 (3%)

Query: 11  ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
           A++YVG L   V+E +L+E F  AGPV++  + +D +T +  GY +V F    DA+ A+ 
Sbjct: 13  ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72

Query: 71  TMNFDVIKGKPIRIMWSQRDPSLRKSGVG-NVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
            MN   + GKPIR+  ++     +   VG N+FI NLD  ID K LYDTFSAFG IL   
Sbjct: 73  IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130

Query: 130 VVC---DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK 186
            +    D   SKGYAF++F + +A+D AIE MNG  L +R + V  +  +K+ + E    
Sbjct: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189

Query: 187 AKE 189
           A E
Sbjct: 190 AAE 192



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 57/186 (30%), Positives = 98/186 (52%), Gaps = 21/186 (11%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
           VY+    E+V +  L ELF Q G  ++  + +D   G+ +G+GFV +   EDA+ A++ M
Sbjct: 15  VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74

Query: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
           N  ++ GK I V +A     +  ++                G N++I NLD  ID++ L 
Sbjct: 75  NMIKLYGKPIRVNKASAH-NKNLDV----------------GANIFIGNLDPEIDEKLLY 117

Query: 312 KEFSPFGSITSAKVMLED---GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
             FS FG I     ++ D   G SKG+ F+ F+S + +  A+  MNG+ + ++P+ V+ A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177

Query: 369 QRKEER 374
            +K+ +
Sbjct: 178 FKKDSK 183



 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 56/183 (30%), Positives = 98/183 (53%), Gaps = 11/183 (6%)

Query: 91  PSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQ 148
           P   ++    V++  LD+ +    L++ F   G +++  +  D      +GY FV F ++
Sbjct: 5   PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64

Query: 149 EAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLK 208
           E AD AI+ MN + L  + + V +  S   +  ++GA      N++I N   E+D++ L 
Sbjct: 65  EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117

Query: 209 ELFSQFGKTLSV-KVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
           + FS FG  L   K+MRDP+ G SKG+ F+++   + ++ A+E MNG+ +  + I V  A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177

Query: 267 QKK 269
            KK
Sbjct: 178 FKK 180


>gi|239753150 PREDICTED: similar to poly(A) binding protein,
           cytoplasmic 1 [Homo sapiens]
          Length = 94

 Score =  124 bits (312), Expect = 2e-28
 Identities = 70/87 (80%), Positives = 75/87 (86%), Gaps = 3/87 (3%)

Query: 558 MLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVD 617
           MLA+APPQEQK++LGERLFPLIQ MH  LAGKITGM LE DNSELLHMLESPESL SKV 
Sbjct: 1   MLASAPPQEQKRILGERLFPLIQAMHPTLAGKITGMWLETDNSELLHMLESPESLHSKVV 60

Query: 618 EAVAVLQAHHAKKEAAQKVGAVAAATS 644
           EAVAVLQAH A KEAAQK  AV +AT+
Sbjct: 61  EAVAVLQAHRA-KEAAQK--AVNSATA 84


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score =  115 bits (287), Expect = 2e-25
 Identities = 70/270 (25%), Positives = 133/270 (49%), Gaps = 16/270 (5%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
           +++ NL + +    +   FS  G   +CK++ D  G+  Y FV F     A  A+  MNG
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68

Query: 161 MLLNDRKVFVGRFKSRKEREAELGA-------KAKEFTNVYIKNFGEEVDDESLKELFSQ 213
             +  ++V V    +   ++ +  +       ++++  +V++ +   E+  E +K  F+ 
Sbjct: 69  RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128

Query: 214 FGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
           FG+    +V++D   GKSKG+GFVS+    DA  A+++M G+ + G+ I    A +K   
Sbjct: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188

Query: 273 -QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE 328
            ++  +   +QL  + +   S      +Y   +   + ++ +R+ FSPFG I   +V  +
Sbjct: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248

Query: 329 DGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
               KG+ FV F+S E A  A+  +NG  +
Sbjct: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274



 Score =  107 bits (266), Expect = 4e-23
 Identities = 78/279 (27%), Positives = 126/279 (45%), Gaps = 36/279 (12%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +LYVG+L  DVTEA++ + FS  GP  + ++  D  T  +  Y +V F +   A  AL  
Sbjct: 8   TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVG-------------NVFIKNLDKSIDNKALYDT 118
           MN   I GK +++ W+    S +K                 +VF+ +L   I  + +   
Sbjct: 66  MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125

Query: 119 FSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRF 173
           F+ FG I   +VV D     SKGY FV F  +  A+ AI++M G  L  R++   +  R 
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185

Query: 174 KSRKEREAELGAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKV 222
               +   E   K   +             VY       + ++ +++ FS FG+ + ++V
Sbjct: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245

Query: 223 MRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
             D     KG+ FV +  HE A  A+  +NG  I G ++
Sbjct: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 51/181 (28%), Positives = 93/181 (51%), Gaps = 6/181 (3%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
           +Y+ N   +V +  + +LFSQ G   + K++ D  G    + FV + +H  A  A+  MN
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67

Query: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
           G++I GK + V  A     ++ +         Q     +   ++++ +L   I  E ++ 
Sbjct: 68  GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF---HVFVGDLSPEITTEDIKA 124

Query: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
            F+PFG I+ A+V+  +  G+SKG+GFV F +  +A  A+ +M G+ +G + +    A R
Sbjct: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184

Query: 371 K 371
           K
Sbjct: 185 K 185



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
           SS    ++Y G + S +TE ++ + FSP G ++ IRV  D       GY++V F     A
Sbjct: 209 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 262

Query: 66  ERALDTMNFDVIKGKPIRIMWSQ 88
             A+ ++N   I+G  ++  W +
Sbjct: 263 AHAIVSVNGTTIEGHVVKCYWGK 285


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score =  114 bits (284), Expect = 4e-25
 Identities = 73/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
           +++ NL + +    +   FS  G   SCK++ +   +  Y FV F     A  A+  MNG
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70

Query: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
             +  ++V V    +   ++ +         +V++ +   E+  E +K  F+ FGK    
Sbjct: 71  RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126

Query: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
           +V++D   GKSKG+GFVS+    DA  A+  M G+ + G+ I    A +K    ++  + 
Sbjct: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186

Query: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
             +QL+ E +   S  +   +Y   +   + D+ +R+ FSPFG I   +V  E    KG+
Sbjct: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242

Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
            FV FS+ E A  A+  +NG  +
Sbjct: 243 SFVRFSTHESAAHAIVSVNGTTI 265



 Score =  113 bits (283), Expect = 5e-25
 Identities = 83/271 (30%), Positives = 126/271 (46%), Gaps = 31/271 (11%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
           +LYVG+L  DVTE ++ + FS  GP  S +    MIT  +    Y +V F +  DA  AL
Sbjct: 10  TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65

Query: 70  DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNIL 126
             MN   I GK +++ W+   PS +K    N   VF+ +L   I  + +   F+ FG I 
Sbjct: 66  AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124

Query: 127 SCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREA 181
             +VV D     SKGY FV F  +  A+ AI  M G  L  R++   +  R     +   
Sbjct: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184

Query: 182 ELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKS 230
           E   K   F +           VY       + D+ +++ FS FG+ + ++V  +     
Sbjct: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239

Query: 231 KGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
           KG+ FV +  HE A  A+  +NG  I G ++
Sbjct: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270



 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 51/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
           +Y+ N   +V +  + +LFSQ G   S K++ +       + FV + +H DA  A+  MN
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69

Query: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
           G++I GK + V  A     ++ +    F              ++++ +L   I  E ++ 
Sbjct: 70  GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115

Query: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
            F+PFG I+ A+V+  +  G+SKG+GFV F +  +A  A+  M G+ +G + +    A R
Sbjct: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175

Query: 371 K 371
           K
Sbjct: 176 K 176



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)

Query: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
           SS    ++Y G + S +T+ ++ + FSP G ++ IRV  +       GY++V F     A
Sbjct: 200 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 253

Query: 66  ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
             A+ ++N   I+G  ++  W +  P + K+
Sbjct: 254 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score =  114 bits (284), Expect = 4e-25
 Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 13/263 (4%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
           +++ NL + +    +   FS  G   +CK++ D  G+  Y FV F     A  A+  MNG
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68

Query: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
             +  ++V V    +   ++ +         +V++ +   E+  E +K  F+ FG+    
Sbjct: 69  RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124

Query: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
           +V++D   GKSKG+GFVS+    DA  A+++M G+ + G+ I    A +K    ++  + 
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184

Query: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
             +QL  + +   S      +Y   +   + ++ +R+ FSPFG I   +V  +    KG+
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240

Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
            FV F+S E A  A+  +NG  +
Sbjct: 241 SFVRFNSHESAAHAIVSVNGTTI 263



 Score =  112 bits (280), Expect = 1e-24
 Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 27/269 (10%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +LYVG+L  DVTEA++ + FS  GP  + ++  D  T  +  Y +V F +   A  AL  
Sbjct: 8   TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNILSC 128
           MN   I GK +++ W+   PS +K    N   VF+ +L   I  + +   F+ FG I   
Sbjct: 66  MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124

Query: 129 KVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREAEL 183
           +VV D     SKGY FV F  +  A+ AI++M G  L  R++   +  R     +   E 
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184

Query: 184 GAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 232
             K   +             VY       + ++ +++ FS FG+ + ++V  D     KG
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239

Query: 233 FGFVSYEKHEDANKAVEEMNGKEISGKII 261
           + FV +  HE A  A+  +NG  I G ++
Sbjct: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 51/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
           +Y+ N   +V +  + +LFSQ G   + K++ D  G    + FV + +H  A  A+  MN
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67

Query: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
           G++I GK + V  A     ++ +    F              ++++ +L   I  E ++ 
Sbjct: 68  GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113

Query: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
            F+PFG I+ A+V+  +  G+SKG+GFV F +  +A  A+ +M G+ +G + +    A R
Sbjct: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173

Query: 371 K 371
           K
Sbjct: 174 K 174



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
           SS    ++Y G + S +TE ++ + FSP G ++ IRV  D       GY++V F     A
Sbjct: 198 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 251

Query: 66  ERALDTMNFDVIKGKPIRIMWSQ 88
             A+ ++N   I+G  ++  W +
Sbjct: 252 AHAIVSVNGTTIEGHVVKCYWGK 274


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score =  113 bits (283), Expect = 5e-25
 Identities = 97/358 (27%), Positives = 170/358 (47%), Gaps = 34/358 (9%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSP--AGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           +L+VG+L+ + +   L    S   A   L++   R  +TR+   + YV+F+   D E+AL
Sbjct: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364

Query: 70  DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
           +     V  G  I++   +   S ++     +  KNL   +    L + F     I   +
Sbjct: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420

Query: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK--- 186
           +V  +  SKG A++ F+T+  A+K  E+  G  ++ R + +     + + +   G K   
Sbjct: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480

Query: 187 -AKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
            + E   + + N      +E+L+E+F    K   +KV ++ NGKSKG+ F+ +   EDA 
Sbjct: 481 WSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGKSKGYAFIEFASFEDAK 537

Query: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
           +A+   N +EI G+ I       ++E Q        + +  +        L++K L +  
Sbjct: 538 EALNSCNKREIEGRAI-------RLELQGPRGSPNARSQPSK-------TLFVKGLSEDT 583

Query: 306 DDEKLRKEFSPFGSITSAKVM-LEDGRSKGFGFVCFSSPEEATKAVTEM-NGRIVGSK 361
            +E L++ F   GS+ +  V   E G SKGFGFV F+S E+A  A   M +G I G+K
Sbjct: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639



 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 79/274 (28%), Positives = 123/274 (44%), Gaps = 31/274 (11%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L   +L   VT+  L E F  A  +    V +D    +S G AY+ F+  ADAE+  + 
Sbjct: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448

Query: 72  MNFDVIKGKPIRIMWS-QRDPSLRKSGVGN---------VFIKNLDKSIDNKALYDTFSA 121
                I G+ I + ++ ++  +    G  N         + + NL  S   + L + F  
Sbjct: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508

Query: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
              I   KV  ++NG SKGYAF+ F + E A +A+   N   +  R +       R E +
Sbjct: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558

Query: 181 AELG---AKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVS 237
              G   A+++    +++K   E+  +E+LKE F   G   +  V     G SKGFGFV 
Sbjct: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVD 616

Query: 238 YEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
           +   EDA  A E M   EI G  + +  A+ K E
Sbjct: 617 FNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650



 Score = 76.3 bits (186), Expect = 8e-14
 Identities = 63/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)

Query: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIK 196
           ++ + +V FE+ E  +KA+E      L   KVF    K  K +  +   K ++   +  K
Sbjct: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398

Query: 197 NFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
           N   +V  + LKE+F    +   V      +GKSKG  ++ ++   DA K  EE  G EI
Sbjct: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454

Query: 257 SGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN--LYIKNLDDTIDDEKLRKEF 314
            G+ I +    +K + Q          +  + S + G +  L + NL  +  +E L++ F
Sbjct: 455 DGRSISLYYTGEKGQNQ--------DYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVF 506

Query: 315 SPFGSITSAKV-MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVAL 367
                 T  KV   ++G+SKG+ F+ F+S E+A +A+   N R +  + + + L
Sbjct: 507 E---KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 5   ASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPAD 64
           A S P  +L+V  L  D TE  L E F  +   +  R+  D  T  S G+ +V+F    D
Sbjct: 566 ARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEED 622

Query: 65  AERALDTMNFDVIKGKPIRIMWSQ 88
           A+ A + M    I G  + + W++
Sbjct: 623 AKAAKEAMEDGEIDGNKVTLDWAK 646


>gi|38201714 ELAV-like 1 [Homo sapiens]
          Length = 326

 Score =  112 bits (279), Expect = 1e-24
 Identities = 81/318 (25%), Positives = 149/318 (46%), Gaps = 49/318 (15%)

Query: 97  GVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKA 154
           G  N+ +  L +++    L   FS+ G + S K++ D+    S GY FV++ T + A++A
Sbjct: 18  GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77

Query: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQF 214
           I  +NG+ L  + +        K   A   ++  +  N+YI      +  + ++++FS+F
Sbjct: 78  INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129

Query: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGK-----IIFVGRAQK 268
           G+ ++ +V+ D   G S+G  F+ ++K  +A +A+   NG +  G      + F     +
Sbjct: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189

Query: 269 K--------------------VERQAELKRKFEQLKQERISRYQGVN----------LYI 298
                                V  QA+ + +F  +  + +S   GVN          ++I
Sbjct: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248

Query: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
            NL    D+  L + F PFG++T+ KV+ +    + KGFGFV  ++ EEA  A+  +NG 
Sbjct: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308

Query: 357 IVGSKPLYVALAQRKEER 374
            +G K L V+    K  +
Sbjct: 309 RLGDKILQVSFKTNKSHK 326



 Score =  100 bits (250), Expect = 3e-21
 Identities = 80/300 (26%), Positives = 136/300 (45%), Gaps = 51/300 (17%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+  L   FS  G V S ++ RD +   SLGY +VN+    DAERA++T
Sbjct: 21  NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N++I  L +++  K + D FS FG I++ +V+
Sbjct: 81  LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138

Query: 132 CDENG--SKGYAFVHFETQEAADKAIEKMNG-MLLNDRKVFVGRFKSRKEREAELGAKAK 188
            D+    S+G AF+ F+ +  A++AI   NG       +    +F +   +   + A   
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNV-ALLS 197

Query: 189 EFTNVYIKNFGEEVDDESLKELFSQFG--------------------------------- 215
           +  +   + FG  V  ++ +  FS  G                                 
Sbjct: 198 QLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADE 257

Query: 216 -----------KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
                         +VKV+RD N  K KGFGFV+   +E+A  A+  +NG  +  KI+ V
Sbjct: 258 GILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317



 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 23/190 (12%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  + L+ LFS  G+  S K++RD   G S G+GFV+Y   +DA +A+ 
Sbjct: 20  TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+   E                    +  NLYI  L  T+  + 
Sbjct: 80  TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
           +   FS FG I +++V+++   G S+G  F+ F    EA +A+T  NG      S+P+ V
Sbjct: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181

Query: 366 ALAQRKEERK 375
             A    + K
Sbjct: 182 KFAANPNQNK 191


>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
          Length = 367

 Score =  111 bits (278), Expect = 2e-24
 Identities = 87/378 (23%), Positives = 172/378 (45%), Gaps = 66/378 (17%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DA++A++T
Sbjct: 40  NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K +   FS +G I++ +++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            D+    S+G  F+ F+ +  A++AI+ +NG                   +  LGA    
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG-------------------QKPLGA---- 194

Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
                                     + ++VK   +P+ K+ G   +++     A +   
Sbjct: 195 -------------------------AEPITVKFANNPSQKT-GQALLTHLYQSSARRYAG 228

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL-----------YI 298
            ++ +    ++  +      V+    L  +F  +  + +S   GV L           ++
Sbjct: 229 PLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFV 288

Query: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
            NL    D+  L + F PFG++T+ KV+ +    + KGFGFV  ++ +EA  A+  +NG 
Sbjct: 289 YNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGY 348

Query: 357 IVGSKPLYVALAQRKEER 374
            +G + L V+    K+ +
Sbjct: 349 RLGERVLQVSFKTSKQHK 366



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 28/215 (13%)

Query: 184 GAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHE 242
           GA     TN+ +    + +  +  K LF   G   S K++RD   G+S G+GFV+Y    
Sbjct: 32  GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPN 91

Query: 243 DANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLD 302
           DA+KA+  +NG ++  K I V  A+                     +  +  NLY+  L 
Sbjct: 92  DADKAINTLNGLKLQTKTIKVSYARPS------------------SASIRDANLYVSGLP 133

Query: 303 DTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IV 358
            T+  +++ + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+  + 
Sbjct: 134 KTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 193

Query: 359 GSKPLYVALAQRKEERK-----AHLTNQYMQRVAG 388
            ++P+ V  A    ++       HL     +R AG
Sbjct: 194 AAEPITVKFANNPSQKTGQALLTHLYQSSARRYAG 228



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L +R + V  FK+ K+ +A
Sbjct: 346 NGYRLGERVLQVS-FKTSKQHKA 367


>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
          Length = 360

 Score =  110 bits (275), Expect = 4e-24
 Identities = 83/330 (25%), Positives = 153/330 (46%), Gaps = 65/330 (19%)

Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
           N+ +  L +++        F + G+I SCK+V D+    S GY FV++     ADKAI  
Sbjct: 40  NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99

Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
           +NG+ L  +  KV   R  S   R+A          N+Y+    + +  + +++LFSQ+G
Sbjct: 100 LNGLKLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMSQKEMEQLFSQYG 149

Query: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269
           + ++ +++ D   G S+G GF+ ++K  +A +A++ +NG++  G      + F     +K
Sbjct: 150 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQK 209

Query: 270 VER-------QAELKR-------------------------KFEQLKQERISRYQGVNL- 296
             +       Q+  +R                         +F  +  + +S   GV L 
Sbjct: 210 TGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLS 269

Query: 297 ----------YIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPE 344
                     ++ NL    D+  L + F PFG++T+ KV+ +    + KGFGFV  ++ +
Sbjct: 270 GGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYD 329

Query: 345 EATKAVTEMNGRIVGSKPLYVALAQRKEER 374
           EA  A+  +NG  +G + L V+    K+ +
Sbjct: 330 EAAMAIASLNGYRLGERVLQVSFKTSKQHK 359



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 45/151 (29%), Positives = 88/151 (58%), Gaps = 4/151 (2%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DA++A++T
Sbjct: 40  NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K +   FS +G I++ +++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160
            D+    S+G  F+ F+ +  A++AI+ +NG
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 28/215 (13%)

Query: 184 GAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHE 242
           GA     TN+ +    + +  +  K LF   G   S K++RD   G+S G+GFV+Y    
Sbjct: 32  GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPN 91

Query: 243 DANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLD 302
           DA+KA+  +NG ++  K I V  A+                     +  +  NLY+  L 
Sbjct: 92  DADKAINTLNGLKLQTKTIKVSYARPS------------------SASIRDANLYVSGLP 133

Query: 303 DTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IV 358
            T+  +++ + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+  + 
Sbjct: 134 KTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 193

Query: 359 GSKPLYVALAQRKEERK-----AHLTNQYMQRVAG 388
            ++P+ V  A    ++       HL     +R AG
Sbjct: 194 AAEPITVKFANNPSQKTGQALLTHLYQSSARRYAG 228



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L +R + V  FK+ K+ +A
Sbjct: 339 NGYRLGERVLQVS-FKTSKQHKA 360



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 17/61 (27%), Positives = 35/61 (57%)

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++V +L  +  E++L++ F P G V +++V RD  T +  G+ +V      +A  A+ ++
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338

Query: 73  N 73
           N
Sbjct: 339 N 339


>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score =  110 bits (274), Expect = 5e-24
 Identities = 83/329 (25%), Positives = 155/329 (47%), Gaps = 64/329 (19%)

Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
           N+ +  L +++  + L   F + G I SCK+V D+    S GY FV++   + A+KAI  
Sbjct: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99

Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
           +NG+ L  +  KV   R  S   R+A          N+Y+    + +  + L++LFSQ+G
Sbjct: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149

Query: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269
           + ++ +++ D   G S+G GF+ ++K  +A +A++ +NG++  G      + F     +K
Sbjct: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209

Query: 270 --------------------VERQAELKR------------KFEQLKQERISRYQGVN-- 295
                               + +QA+  R            +F  +  + ++   G+N  
Sbjct: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269

Query: 296 --------LYIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEE 345
                   +++ NL    D+  L + F PFG++T+ KV+      + KGFGFV  ++ +E
Sbjct: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329

Query: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEER 374
           A  A+  +NG  +G + L V+    K  +
Sbjct: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 48/151 (31%), Positives = 89/151 (58%), Gaps = 4/151 (2%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+  L   F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 40  NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160
            D+    S+G  F+ F+ +  A++AI+ +NG
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188



 Score = 82.8 bits (203), Expect = 9e-16
 Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 27/196 (13%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  E LK LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 39  TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 99  TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200

Query: 366 ALAQRKEERKAHLTNQ 381
             A    ++    TNQ
Sbjct: 201 KFANNPSQK----TNQ 212



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L DR + V  FK+ K  +A
Sbjct: 338 NGYRLGDRVLQVS-FKTNKTHKA 359



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 18/61 (29%), Positives = 35/61 (57%)

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++V +L  D  E++L++ F P G V +++V RD  T +  G+ +V      +A  A+ ++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337

Query: 73  N 73
           N
Sbjct: 338 N 338


>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
          Length = 392

 Score =  109 bits (273), Expect = 7e-24
 Identities = 81/284 (28%), Positives = 126/284 (44%), Gaps = 40/284 (14%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG---------------YAY 56
           +LYVG+L  DVTE ++ + FS  GP  S ++  +    R +                Y +
Sbjct: 10  TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69

Query: 57  VNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNK 113
           V F +  DA  AL  MN   I GK +++ W+   PS +K    N   VF+ +L   I  +
Sbjct: 70  VEFYEHRDAAAALAAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTE 128

Query: 114 ALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV--- 168
            +   F+ FG I   +VV D     SKGY FV F  +  A+ AI  M G  L  R++   
Sbjct: 129 DIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTN 188

Query: 169 FVGRFKSRKEREAELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKT 217
           +  R     +   E   K   F +           VY       + D+ +++ FS FG+ 
Sbjct: 189 WATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQI 248

Query: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
           + ++V  +     KG+ FV +  HE A  A+  +NG  I G ++
Sbjct: 249 MEIRVFPE-----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 287



 Score =  105 bits (263), Expect = 1e-22
 Identities = 76/280 (27%), Positives = 130/280 (46%), Gaps = 30/280 (10%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE------NGSKG-----------YAFV 143
           +++ NL + +    +   FS  G   SCK++ ++      N S G           Y FV
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70

Query: 144 HFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVD 203
            F     A  A+  MNG  +  ++V V    +   ++ +         +V++ +   E+ 
Sbjct: 71  EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEIT 126

Query: 204 DESLKELFSQFGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262
            E +K  F+ FGK    +V++D   GKSKG+GFVS+    DA  A+  M G+ + G+ I 
Sbjct: 127 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR 186

Query: 263 VGRAQKKVER-QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFG 318
              A +K    ++  +   +QL+ E +   S  +   +Y   +   + D+ +R+ FSPFG
Sbjct: 187 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG 246

Query: 319 SITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
            I   +V  E    KG+ FV FS+ E A  A+  +NG  +
Sbjct: 247 QIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTI 282



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 55/197 (27%), Positives = 96/197 (48%), Gaps = 32/197 (16%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRD-PNGK----SKGFG-----------FV 236
           +Y+ N   +V +  + +LFSQ G   S K++ + P+ +    S GF            FV
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70

Query: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL 296
            + +H DA  A+  MNG++I GK + V  A     ++ +    F              ++
Sbjct: 71  EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHF--------------HV 116

Query: 297 YIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMN 354
           ++ +L   I  E ++  F+PFG I+ A+V+  +  G+SKG+GFV F +  +A  A+  M 
Sbjct: 117 FVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMG 176

Query: 355 GRIVGSKPLYVALAQRK 371
           G+ +G + +    A RK
Sbjct: 177 GQWLGGRQIRTNWATRK 193



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)

Query: 6   SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
           SS    ++Y G + S +T+ ++ + FSP G ++ IRV  +       GY++V F     A
Sbjct: 217 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 270

Query: 66  ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
             A+ ++N   I+G  ++  W +  P + K+
Sbjct: 271 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 301


>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
          Length = 380

 Score =  108 bits (271), Expect = 1e-23
 Identities = 89/377 (23%), Positives = 163/377 (43%), Gaps = 58/377 (15%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 47  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            D+    S+G  F+ F+ +  A++AI+ +NG                         K   
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200

Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
            T      F      +S + L SQ        + + PN +  G        H  A    +
Sbjct: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQA----Q 242

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN----------LYIK 299
                 +      V R        +    +F  +  + ++   G+N          +++ 
Sbjct: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302

Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
           NL    D+  L + F PFG++ + KV+      + KGFGFV  ++ +EA  A+  +NG  
Sbjct: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362

Query: 358 VGSKPLYVALAQRKEER 374
           +G + L V+    K  +
Sbjct: 363 LGDRVLQVSFKTNKAHK 379



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  E  + LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 46  TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207

Query: 366 ALAQRKEERKA 376
             A    ++ +
Sbjct: 208 KFANNPSQKSS 218



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L DR + V  FK+ K  ++
Sbjct: 359 NGYRLGDRVLQVS-FKTNKAHKS 380


>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
          Length = 369

 Score =  107 bits (268), Expect = 3e-23
 Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 50  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 110 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 167

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            D+    S+G  F+ F+ +  A++AI+ +NG                         K   
Sbjct: 168 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 203

Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
            T      F      +S + L SQ        + + PN +  G        H  A +   
Sbjct: 204 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 247

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
                          R    +     +KR F  +  + ++   G+N+          ++ 
Sbjct: 248 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 291

Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
           NL    D+  L + F PFG++ + KV+      + KGFGFV  ++ +EA  A+  +NG  
Sbjct: 292 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 351

Query: 358 VGSKPLYVALAQRKEER 374
           +G + L V+    K  +
Sbjct: 352 LGDRVLQVSFKTNKAHK 368



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  E  + LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 49  TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 108

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 109 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 150

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 151 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 210

Query: 366 ALAQRKEERKA 376
             A    ++ +
Sbjct: 211 KFANNPSQKSS 221



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L DR + V  FK+ K  ++
Sbjct: 348 NGYRLGDRVLQVS-FKTNKAHKS 369


>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
          Length = 366

 Score =  107 bits (268), Expect = 3e-23
 Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 47  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            D+    S+G  F+ F+ +  A++AI+ +NG                         K   
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200

Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
            T      F      +S + L SQ        + + PN +  G        H  A +   
Sbjct: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 244

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
                          R    +     +KR F  +  + ++   G+N+          ++ 
Sbjct: 245 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 288

Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
           NL    D+  L + F PFG++ + KV+      + KGFGFV  ++ +EA  A+  +NG  
Sbjct: 289 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 348

Query: 358 VGSKPLYVALAQRKEER 374
           +G + L V+    K  +
Sbjct: 349 LGDRVLQVSFKTNKAHK 365



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  E  + LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 46  TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207

Query: 366 ALAQRKEERKA 376
             A    ++ +
Sbjct: 208 KFANNPSQKSS 218



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L DR + V  FK+ K  ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366


>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
          Length = 383

 Score =  107 bits (268), Expect = 3e-23
 Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 64  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            D+    S+G  F+ F+ +  A++AI+ +NG                         K   
Sbjct: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 217

Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
            T      F      +S + L SQ        + + PN +  G        H  A +   
Sbjct: 218 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 261

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
                          R    +     +KR F  +  + ++   G+N+          ++ 
Sbjct: 262 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305

Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
           NL    D+  L + F PFG++ + KV+      + KGFGFV  ++ +EA  A+  +NG  
Sbjct: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365

Query: 358 VGSKPLYVALAQRKEER 374
           +G + L V+    K  +
Sbjct: 366 LGDRVLQVSFKTNKAHK 382



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  E  + LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 63  TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224

Query: 366 ALAQRKEERKA 376
             A    ++ +
Sbjct: 225 KFANNPSQKSS 235



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L DR + V  FK+ K  ++
Sbjct: 362 NGYRLGDRVLQVS-FKTNKAHKS 383


>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
          Length = 366

 Score =  107 bits (268), Expect = 3e-23
 Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)

Query: 12  SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
           +L V  L  ++T+      F   G + S ++ RD IT +SLGY +VN+  P DAE+A++T
Sbjct: 47  NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106

Query: 72  MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           +N   ++ K I++ +++  PS       N+++  L K++  K L   FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164

Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            D+    S+G  F+ F+ +  A++AI+ +NG                         K   
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200

Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
            T      F      +S + L SQ        + + PN +  G        H  A +   
Sbjct: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 244

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
                          R    +     +KR F  +  + ++   G+N+          ++ 
Sbjct: 245 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 288

Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
           NL    D+  L + F PFG++ + KV+      + KGFGFV  ++ +EA  A+  +NG  
Sbjct: 289 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 348

Query: 358 VGSKPLYVALAQRKEER 374
           +G + L V+    K  +
Sbjct: 349 LGDRVLQVSFKTNKAHK 365



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)

Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
           TN+ +    + +  E  + LF   G+  S K++RD   G+S G+GFV+Y   +DA KA+ 
Sbjct: 46  TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105

Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
            +NG  +  K I V  A+                     +  +  NLY+  L  T+  ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147

Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
           L + FS +G I +++++++   G S+G GF+ F    EA +A+  +NG+     ++P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207

Query: 366 ALAQRKEERKA 376
             A    ++ +
Sbjct: 208 KFANNPSQKSS 218



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
           +F+ NL    D   L+  F  FG + + KV+ D   N  KG+ FV     + A  AI  +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344

Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
           NG  L DR + V  FK+ K  ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score =  106 bits (265), Expect = 6e-23
 Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)

Query: 60  QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118
           QQ  + + A  TM F D +   P++ M +QR  +L  + +  V++ ++   +    +   
Sbjct: 50  QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 105

Query: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
           F+ FG I S  +  D      KG+AFV +E  EAA  A+E+MN ++L  R + VGR  + 
Sbjct: 106 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 165

Query: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232
            + +    +L  +A+ F  +Y+ +  +++ D+ +K +F  FGK  S  + RDP  GK KG
Sbjct: 166 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 225

Query: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
           +GF+ YEK + +  AV  MN  ++ G+ + VG+A
Sbjct: 226 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 259



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           M  +YVG ++ ++ E  + + F+P GP+ SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 85  MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 144

Query: 70  DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
           + MN  ++ G+ I++       Q  P +            +++ ++ + + +  +   F 
Sbjct: 145 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 204

Query: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
           AFG I SC +  D      KGY F+ +E  +++  A+  MN   L  + + VG+
Sbjct: 205 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 258



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
           VY+ +   E+ ++++++ F+ FG   S+ +  D    K KGF FV YE  E A  A+E+M
Sbjct: 88  VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147

Query: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
           N   + G+ I VGR      AQ  +++ AE  R F +             +Y+ ++   +
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 194

Query: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN   +G + L
Sbjct: 195 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 254

Query: 364 YVALA 368
            V  A
Sbjct: 255 RVGKA 259


>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
           sapiens]
          Length = 559

 Score =  106 bits (265), Expect = 6e-23
 Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)

Query: 60  QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118
           QQ  + + A  TM F D +   P++ M +QR  +L  + +  V++ ++   +    +   
Sbjct: 93  QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148

Query: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
           F+ FG I S  +  D      KG+AFV +E  EAA  A+E+MN ++L  R + VGR  + 
Sbjct: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208

Query: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232
            + +    +L  +A+ F  +Y+ +  +++ D+ +K +F  FGK  S  + RDP  GK KG
Sbjct: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268

Query: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
           +GF+ YEK + +  AV  MN  ++ G+ + VG+A
Sbjct: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           M  +YVG ++ ++ E  + + F+P GP+ SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187

Query: 70  DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
           + MN  ++ G+ I++       Q  P +            +++ ++ + + +  +   F 
Sbjct: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247

Query: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
           AFG I SC +  D      KGY F+ +E  +++  A+  MN   L  + + VG+
Sbjct: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)

Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
           VY+ +   E+ ++++++ F+ FG   S+ +  D    K KGF FV YE  E A  A+E+M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190

Query: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
           N   + G+ I VGR      AQ  +++ AE  R F +             +Y+ ++   +
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237

Query: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN   +G + L
Sbjct: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 297

Query: 364 YVALA 368
            V  A
Sbjct: 298 RVGKA 302


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score =  102 bits (254), Expect = 1e-21
 Identities = 56/172 (32%), Positives = 96/172 (55%), Gaps = 6/172 (3%)

Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
           V++ ++   +    +   F+ FG I S  +  D      KG+AFV +E  EAA  A+E+M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173

Query: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
           N ++L  R + VGR  +  + +    +L  +A+ F  +Y+ +  +++ D+ +K +F  FG
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233

Query: 216 KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
           K  S  + RDP  GK KG+GF+ YEK + +  AV  MN  ++ G+ + VG+A
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
           M  +YVG ++ ++ E  + + F+P GP+ SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170

Query: 70  DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
           + MN  ++ G+ I++       Q  P +            +++ ++ + + +  +   F 
Sbjct: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230

Query: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
           AFG I SC +  D      KGY F+ +E  +++  A+  MN   L  + + VG+
Sbjct: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 115/239 (48%), Gaps = 31/239 (12%)

Query: 146 ETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGAKAKE----FTNVYIKNF 198
           E QEA  KA  K   M  + + V V +  + ++++    ++ A+ +        VY+ + 
Sbjct: 62  EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119

Query: 199 GEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEIS 257
             E+ ++++++ F+ FG   S+ +  D    K KGF FV YE  E A  A+E+MN   + 
Sbjct: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179

Query: 258 GKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
           G+ I VGR      AQ  +++ AE  R F +             +Y+ ++   + D+ ++
Sbjct: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226

Query: 312 KEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
             F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN   +G + L V  A
Sbjct: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285


>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 6 [Homo sapiens]
          Length = 562

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 74/286 (25%), Positives = 142/286 (49%), Gaps = 25/286 (8%)

Query: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
           ++VG +  D+ E  L   F  AGP+  +R+  D +T  + GYA+V F     A+ A+   
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223

Query: 73  N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
           N  ++  GK I +  S  +  L        F+ ++ KS   + + + FS     L+  ++
Sbjct: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275

Query: 132 C----DENGSKGYAFVHFETQEAADKAIEK-MNGMLLNDRKVFVGRFKSR-KEREAELGA 185
                D+  ++G+ F+ +E  + A +A  + M+G +     V    +    ++ + E+ A
Sbjct: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335

Query: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
           K K    ++++N    V +E L++ FSQFGK   VK ++D       + F+ +++ + A 
Sbjct: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAV 385

Query: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291
           KA+EEMNGK++ G+ I +  A+   +++ E K + +  K +    Y
Sbjct: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 431



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 78/310 (25%), Positives = 144/310 (46%), Gaps = 49/310 (15%)

Query: 79  GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136
           G P   ++S + PS+       +F+  + + +    L   F   G I   +++ D     
Sbjct: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201

Query: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195
           ++GYAFV F T+EAA +A++     L N+ ++  G+          +G       N +++
Sbjct: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247

Query: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEE-M 251
            +  +    E + E FS+  + L+  ++    D   K++GF F+ YE H+ A +A    M
Sbjct: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307

Query: 252 NGK-EISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKL 310
           +GK ++ G +  V  A    +   E+  K + L             +++NL +T+ +E L
Sbjct: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVL-------------FVRNLANTVTEEIL 354

Query: 311 RKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA-- 368
            K FS FG +   K      + K + F+ F   + A KA+ EMNG+ +  + + +  A  
Sbjct: 355 EKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408

Query: 369 --QRKEERKA 376
             Q+++ERKA
Sbjct: 409 PDQKRKERKA 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,685,833
Number of Sequences: 37866
Number of extensions: 1271055
Number of successful extensions: 7396
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 5120
Number of HSP's gapped (non-prelim): 1367
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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