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Search of human proteins with 4504715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2
[Homo sapiens]
(644 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 1276 0.0
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 1266 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 1214 0.0
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 960 0.0
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 876 0.0
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 792 0.0
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 560 e-159
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 490 e-138
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 318 1e-86
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 318 1e-86
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 125 1e-28
gi|239753150 PREDICTED: similar to poly(A) binding protein, cyto... 124 2e-28
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 115 2e-25
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 114 4e-25
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 114 4e-25
gi|55956788 nucleolin [Homo sapiens] 113 5e-25
gi|38201714 ELAV-like 1 [Homo sapiens] 112 1e-24
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 111 2e-24
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 110 4e-24
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 110 5e-24
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 109 7e-24
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 108 1e-23
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 107 3e-23
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 107 3e-23
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 107 3e-23
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 107 3e-23
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 106 6e-23
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 106 6e-23
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 102 1e-21
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 94 5e-19
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 1276 bits (3302), Expect = 0.0
Identities = 644/644 (100%), Positives = 644/644 (100%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
Query: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF 480
PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF
Sbjct: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF 480
Query: 481 GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 540
GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ
Sbjct: 481 GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 540
Query: 541 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 600
APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS
Sbjct: 541 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 600
Query: 601 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Sbjct: 601 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 1266 bits (3275), Expect = 0.0
Identities = 644/660 (97%), Positives = 644/660 (97%), Gaps = 16/660 (2%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
Query: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPT------------ 468
PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPT
Sbjct: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTT 480
Query: 469 ----GSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYK 524
GSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYK
Sbjct: 481 TQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYK 540
Query: 525 YASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHS 584
YASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHS
Sbjct: 541 YASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHS 600
Query: 585 NLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
NLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Sbjct: 601 NLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 660
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 1214 bits (3142), Expect = 0.0
Identities = 620/644 (96%), Positives = 623/644 (96%), Gaps = 13/644 (2%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK
Sbjct: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP
Sbjct: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
Query: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMDF 480
PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTG+
Sbjct: 421 PYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGN---------- 470
Query: 481 GGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 540
A +GL + Q GVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ
Sbjct: 471 ---APASRGLPTTTQRVGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQ 527
Query: 541 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 600
APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS
Sbjct: 528 APQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNS 587
Query: 601 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 644
ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS
Sbjct: 588 ELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 631
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 960 bits (2481), Expect = 0.0
Identities = 500/652 (76%), Positives = 553/652 (84%), Gaps = 30/652 (4%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MN +A SYPMASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRDMITRRSLGYAYVNFQ
Sbjct: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+FIKNLDKSIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSCKVVCDENGSKGY FVHFETQEAA++AIEKMNGMLLNDRKVFVGRFKSRKERE
Sbjct: 121 AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE 180
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AELGA+AKEFTNVYIKNFGE++DDE LK+LF +FG LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKRKFEQ+KQ+RI+RYQGVNLY+KN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDD IDDE+LRKEFSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPA-AGGYFVPAVPQAQGR 419
KPLYVALAQRKEER+AHLTNQYMQR+A +RA+P N ++N +QPA GYF+ A+PQ Q R
Sbjct: 361 KPLYVALAQRKEERQAHLTNQYMQRMASVRAVP-NPVINPYQPAPPSGYFMAAIPQTQNR 419
Query: 420 PPYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAM 478
YY P+Q+AQ+RP+PRW QG RP FQ MP AIR + PRP + P S+ P +
Sbjct: 420 AAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVM-- 477
Query: 479 DFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAP----RAVAPYKYASSVRSP-- 532
+ Q + + T+ Q + PR A AAAA R V YKYA+ VR+P
Sbjct: 478 -------STQRVAN--------TSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQ 522
Query: 533 HPAIQP-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKIT 591
H QP + QPAVHVQGQEPLTASMLA+APPQEQKQMLGERLFPLIQ MH LAGKIT
Sbjct: 523 HLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKIT 582
Query: 592 GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAAT 643
GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAH A KEAAQK AV +AT
Sbjct: 583 GMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQA-KEAAQK--AVNSAT 631
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 876 bits (2264), Expect = 0.0
Identities = 464/647 (71%), Positives = 522/647 (80%), Gaps = 25/647 (3%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MN + SYP ASLYVGDLH DVTEAMLYEKFSPAGP+LSIR+CRD+IT S YAYVNFQ
Sbjct: 1 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
DAE ALDTMNFDVIKGKP+RIMWSQRDPSLRKSGVGN+F+KNLDKSI+NKALYDT S
Sbjct: 61 HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVS 120
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFGNILSC VVCDENGSKGY FVHFET EAA++AI+KMNGMLLN RKVFVG+FKSRKERE
Sbjct: 121 AFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKERE 180
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AELGA+AKEF NVYIKNFGE++DDE LK+LF +FG LSVKVM D +GKSKGFGFVS+E+
Sbjct: 181 AELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER 240
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HEDA KAV+EMNGKE++GK I+VGRAQKKVERQ ELKR FEQ+KQ+RI+RYQ VNLY+KN
Sbjct: 241 HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKN 300
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDD IDDE+LRK FSPFG+ITSAKVM+E GRSKGFGFVCFSSPEEATKAVTEMNGRIV +
Sbjct: 301 LDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT 360
Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
KPLYVALAQRKEER+A+LTN+YMQR+A +RA+P NQ P + GYF+ AVPQ Q
Sbjct: 361 KPLYVALAQRKEERQAYLTNEYMQRMASVRAVP-----NQRAPPS-GYFMTAVPQTQNHA 414
Query: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMD 479
YY P+Q+A++RP+PRW QG RP FQ PSAIR PR + P S+ P +
Sbjct: 415 AYYPPSQIARLRPSPRWTAQGARPHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVM--- 471
Query: 480 FGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSP--HPAIQ 537
+ Q+ S Q+ G A A AA A A R V YKYA+ VR+P H Q
Sbjct: 472 -----STQRVANTSTQTVGPRPA----AAAAAAATPAVRTVPRYKYAAGVRNPQQHRNAQ 522
Query: 538 P-LQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLE 596
P + Q AVHVQGQE LTAS LA+APPQ+QKQMLGERLFPLIQ MH LAGKITGMLLE
Sbjct: 523 PQVTMQQLAVHVQGQETLTASRLASAPPQKQKQMLGERLFPLIQAMHPTLAGKITGMLLE 582
Query: 597 IDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAAT 643
IDNSELL+MLESPESLRSKVDEAVAVLQAH A KEA QK AV +AT
Sbjct: 583 IDNSELLYMLESPESLRSKVDEAVAVLQAHQA-KEATQK--AVNSAT 626
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 792 bits (2045), Expect = 0.0
Identities = 408/632 (64%), Positives = 488/632 (77%), Gaps = 25/632 (3%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MNA+ S YP+ASLYVGDLH DVTEAMLYEKFSPAGP+LSIRVCRD+ TRRSLGYAY+NFQ
Sbjct: 1 MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQ 60
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
QPADAERALDTMNF+++KG+PIRIMWSQRDP LRKSGVGN+FIKNL+ SIDNKALYDTFS
Sbjct: 61 QPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFS 120
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
FGNILSCKV CDE+GS+G+ FVHFET EAA +AI MNGMLLNDRKVFVG FKSR+ERE
Sbjct: 121 TFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRRERE 180
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AELGA+A EFTN+Y+KN +VD++ L++LFSQFGK LSVKVMRD +G S+ FGFV++EK
Sbjct: 181 AELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEK 240
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HE+A KAV MNGKE+SG++++ GRAQK+VERQ ELKR+FEQ+KQ+R+ RYQGVNLY+KN
Sbjct: 241 HEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKN 300
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDD+IDD+KLRKEFSP+G ITSAKVM E G SKGFGFVCFSSPEEATKAVTEMNGRIVG+
Sbjct: 301 LDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGT 360
Query: 361 KPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRP 420
KPLYVALAQRKEERKA LTNQYMQR++ MR L +N +L FQ + YF+PA+PQ +
Sbjct: 361 KPLYVALAQRKEERKAILTNQYMQRLSTMRTL-SNPLLGSFQQPS-SYFLPAMPQPPAQA 418
Query: 421 PYYTPNQLAQMRPNPRW-QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRLAMD 479
YY + +P PRW Q RP + + P + + ++ P
Sbjct: 419 AYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVP------ 472
Query: 480 FGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPL 539
+ + + + + T Q P R + P K +S+ S +
Sbjct: 473 --------RTVPHTQRVANIGT--QTTGPSGVGCCTPGRPLLPCKCSSAAHSTY------ 516
Query: 540 QAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDN 599
+ +PAVH+ GQEPLTASMLAAAP EQKQM+GERL+PLI +H+ LAGKITGMLLEIDN
Sbjct: 517 RVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDN 576
Query: 600 SELLHMLESPESLRSKVDEAVAVLQAHHAKKE 631
SELL MLESPESL +K+DEAVAVLQAH A ++
Sbjct: 577 SELLLMLESPESLHAKIDEAVAVLQAHQAMEQ 608
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 560 bits (1444), Expect = e-159
Identities = 279/370 (75%), Positives = 323/370 (87%), Gaps = 1/370 (0%)
Query: 1 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQ 60
MN AA Y MASLYVGDLH+DVTE +L+ KFS GPVLSIR+CRD +TRRSLGYAYVNF
Sbjct: 1 MNVAAK-YRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFL 59
Query: 61 QPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFS 120
Q ADA++ALDTMNFD+IKGK IR+MWSQRD LR+SG+GNVFIKNLDKSIDNK LY+ FS
Sbjct: 60 QLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Query: 121 AFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
AFG ILS KV+ D+ GSKGYAFVHF+ Q AAD+AIE+MNG LL KVFVGRFK+RK+RE
Sbjct: 120 AFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDRE 179
Query: 181 AELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEK 240
AEL +KA EFTNVYIKNFG ++DDE LK++FS++GKTLSVKVM D +GKSKGFGFVS++
Sbjct: 180 AELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDS 239
Query: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
HE A KAVEEMNG++I+G++IFVGRAQKKVERQAELK+ FEQLK+ERI QGV LYIKN
Sbjct: 240 HEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKN 299
Query: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGS 360
LDDTIDDEKLR EFS FGSI+ KVM E+G+SKGFG +CFSSPE+ATKA+TEMNGRI+GS
Sbjct: 300 LDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGS 359
Query: 361 KPLYVALAQR 370
KPL +ALAQR
Sbjct: 360 KPLSIALAQR 369
Score = 184 bits (468), Expect = 2e-46
Identities = 111/293 (37%), Positives = 169/293 (57%), Gaps = 20/293 (6%)
Query: 95 KSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAAD 152
K + ++++ +L + L+ FS G +LS ++ D+ S GYA+V+F A
Sbjct: 6 KYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQ 65
Query: 153 KAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFS 212
KA++ MN ++ + + + +R+A L + NV+IKN + +D+++L E FS
Sbjct: 66 KALDTMNFDIIKGKSIRL----MWSQRDAYL--RRSGIGNVFIKNLDKSIDNKTLYEHFS 119
Query: 213 QFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
FGK LS KVM D G SKG+ FV ++ A++A+EEMNGK + G +FVGR + + +R
Sbjct: 120 AFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDR 178
Query: 273 QAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED-GR 331
+AEL+ K + N+YIKN +DDE+L+ FS +G S KVM + G+
Sbjct: 179 EAELRSKASEF----------TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228
Query: 332 SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQ 384
SKGFGFV F S E A KAV EMNGR + + ++V AQ+K ER+A L + Q
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQ 281
Score = 103 bits (257), Expect = 5e-22
Identities = 68/206 (33%), Positives = 114/206 (55%), Gaps = 26/206 (12%)
Query: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
++Y+ + +V ++ L FS G LS+++ RD +S G+ +V++ + DA KA++
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
MN I GK I + +Q R A L+R G+ N++IKNLD +ID++
Sbjct: 71 MNFDIIKGKSIRLMWSQ----RDAYLRRS-------------GIGNVFIKNLDKSIDNKT 113
Query: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
L + FS FG I S+KVM +D SKG+ FV F + A +A+ EMNG+++ ++V +
Sbjct: 114 LYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173
Query: 370 RKEERKAHL-------TNQYMQRVAG 388
+++R+A L TN Y++ G
Sbjct: 174 NRKDREAELRSKASEFTNVYIKNFGG 199
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 490 bits (1261), Expect = e-138
Identities = 243/365 (66%), Positives = 300/365 (82%), Gaps = 1/365 (0%)
Query: 8 YPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAER 67
Y A+LYVGDL DVTE MLY+KF PAGP+ R+CRD +TR LGY YVNF+ PADAE
Sbjct: 15 YLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEW 74
Query: 68 ALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILS 127
AL+TMNFD+I GKP R+MWSQ D LRKSGVGN+FIKNLDKSIDN+AL+ FSAFGNILS
Sbjct: 75 ALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILS 134
Query: 128 CKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKA 187
CKVVCD+NGSKGYA+VHF++ AA++AI MNG+ LN+R+V+VGRFK +ER AE+ +
Sbjct: 135 CKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRD 194
Query: 188 K-EFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
+ FTNV++KN G+++DDE LKELF ++G T SVKV+RD +GKSKGFGFV YE HE A K
Sbjct: 195 RATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQK 254
Query: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTID 306
AV +++GK I GK+++VGRAQKK+ER AEL+R+FE+L+ + SR GV +YIKNLD+TI+
Sbjct: 255 AVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETIN 314
Query: 307 DEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVA 366
DEKL++EFS FGSI+ AKVM+E G+ KGFG VCFSS EEATKAV EMNGRIVGSKPL+V
Sbjct: 315 DEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVT 374
Query: 367 LAQRK 371
L Q +
Sbjct: 375 LGQAR 379
Score = 153 bits (386), Expect = 5e-37
Identities = 97/285 (34%), Positives = 155/285 (54%), Gaps = 19/285 (6%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
+++ +LD + LY F G + ++ D GY +V+F A+ A+ M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 159 NGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTL 218
N L+N K F + +R + G N++IKN + +D+ +L LFS FG L
Sbjct: 80 NFDLING-KPFRLMWSQPDDRLRKSGVG-----NIFIKNLDKSIDNRALFYLFSAFGNIL 133
Query: 219 SVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR 278
S KV+ D NG SKG+ +V ++ AN+A+ MNG ++ + ++VGR + ER AE++
Sbjct: 134 SCKVVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRT 192
Query: 279 KFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGF 337
+ R N+++KN+ D IDDEKL++ F +G S KV+ + G+SKGFGF
Sbjct: 193 R---------DRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGF 243
Query: 338 VCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQY 382
V + + E A KAV +++G+ + K LYV AQ+K ER A L ++
Sbjct: 244 VRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRF 288
Score = 77.8 bits (190), Expect = 3e-14
Identities = 50/183 (27%), Positives = 98/183 (53%), Gaps = 19/183 (10%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+++V ++ D+ + L E F GP S++V RD + +S G+ +V ++ A++A+
Sbjct: 200 NVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVLD 258
Query: 72 MNFDVIKGKPIRIMWSQRD-----------------PSLRKSGVGNVFIKNLDKSIDNKA 114
++ I GK + + +Q+ R GV ++IKNLD++I+++
Sbjct: 259 LHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVP-IYIKNLDETINDEK 317
Query: 115 LYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK 174
L + FS+FG+I KV+ + KG+ V F + E A KA+++MNG ++ + + V +
Sbjct: 318 LKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
Query: 175 SRK 177
+R+
Sbjct: 378 ARR 380
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/100 (25%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 290 RYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSK--GFGFVCFSSPEEAT 347
+Y LY+ +LD + ++ L K+F P G + ++ + G+G+V F P +A
Sbjct: 14 KYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAE 73
Query: 348 KAVTEMNGRIVGSKPLYVALAQRKEE-RKAHLTNQYMQRV 386
A+ MN ++ KP + +Q + RK+ + N +++ +
Sbjct: 74 WALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNL 113
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 318 bits (814), Expect = 1e-86
Identities = 151/197 (76%), Positives = 176/197 (89%)
Query: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
MASLYVGDLH +VTEAMLYEKFSPAGP+LSIR+CRD ITRRSLGYAYVN+QQP DA+RAL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
+T+NFDVIKG+P+RIMWSQRDPSLRKSGVGNVFIKNL K+IDNKALY+ FSAFGNILSCK
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
V CDE G KGY FVHF+ QE+A++AI+ MNGM LN RK+FVGRFKS KEREAE GA A++
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 190 FTNVYIKNFGEEVDDES 206
T+ +K+F E+ D+E+
Sbjct: 181 STSADVKDFEEDTDEEA 197
Score = 103 bits (257), Expect = 5e-22
Identities = 62/180 (34%), Positives = 104/180 (57%), Gaps = 9/180 (5%)
Query: 98 VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAI 155
+ ++++ +L + LY+ FS G ILS ++ D+ S GYA+V+++ A +A+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
E +N ++ R V + +R+ L + NV+IKN G+ +D+++L +FS FG
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 216 KTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAE 275
LS KV D G KG+GFV ++K E A +A++ MNG ++ + IFVGR + ER+AE
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 95.1 bits (235), Expect = 2e-19
Identities = 60/187 (32%), Positives = 100/187 (53%), Gaps = 19/187 (10%)
Query: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
++Y+ + EV + L E FS G LS+++ RD +S G+ +V+Y++ DA +A+E
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
+N I G+ + + +Q+ + R GV N++IKNL TID++
Sbjct: 63 LNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
L FS FG+I S KV ++ KG+GFV F E A +A+ MNG + + ++V +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 370 RKEERKA 376
+ER+A
Sbjct: 166 SHKEREA 172
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 318 bits (814), Expect = 1e-86
Identities = 151/197 (76%), Positives = 176/197 (89%)
Query: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
MASLYVGDLH +VTEAMLYEKFSPAGP+LSIR+CRD ITRRSLGYAYVN+QQP DA+RAL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
+T+NFDVIKG+P+RIMWSQRDPSLRKSGVGNVFIKNL K+IDNKALY+ FSAFGNILSCK
Sbjct: 61 ETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCK 120
Query: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
V CDE G KGY FVHF+ QE+A++AI+ MNGM LN RK+FVGRFKS KEREAE GA A++
Sbjct: 121 VACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQ 180
Query: 190 FTNVYIKNFGEEVDDES 206
T+ +K+F E+ D+E+
Sbjct: 181 STSADVKDFEEDTDEEA 197
Score = 103 bits (257), Expect = 5e-22
Identities = 62/180 (34%), Positives = 104/180 (57%), Gaps = 9/180 (5%)
Query: 98 VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAI 155
+ ++++ +L + LY+ FS G ILS ++ D+ S GYA+V+++ A +A+
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
E +N ++ R V + +R+ L + NV+IKN G+ +D+++L +FS FG
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL--RKSGVGNVFIKNLGKTIDNKALYNIFSAFG 114
Query: 216 KTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAE 275
LS KV D G KG+GFV ++K E A +A++ MNG ++ + IFVGR + ER+AE
Sbjct: 115 NILSCKVACDEKGP-KGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAE 173
Score = 95.1 bits (235), Expect = 2e-19
Identities = 60/187 (32%), Positives = 100/187 (53%), Gaps = 19/187 (10%)
Query: 192 NVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEE 250
++Y+ + EV + L E FS G LS+++ RD +S G+ +V+Y++ DA +A+E
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 251 MNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGV-NLYIKNLDDTIDDEK 309
+N I G+ + + +Q+ + R GV N++IKNL TID++
Sbjct: 63 LNFDVIKGRPVRIMWSQR-----------------DPSLRKSGVGNVFIKNLGKTIDNKA 105
Query: 310 LRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
L FS FG+I S KV ++ KG+GFV F E A +A+ MNG + + ++V +
Sbjct: 106 LYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFK 165
Query: 370 RKEERKA 376
+ER+A
Sbjct: 166 SHKEREA 172
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 125 bits (314), Expect = 1e-28
Identities = 75/183 (40%), Positives = 107/183 (58%), Gaps = 7/183 (3%)
Query: 11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALD 70
A++YVG L V+E +L+E F AGPV++ + +D +T + GY +V F DA+ A+
Sbjct: 13 ATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIK 72
Query: 71 TMNFDVIKGKPIRIMWSQRDPSLRKSGVG-NVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
MN + GKPIR+ ++ + VG N+FI NLD ID K LYDTFSAFG IL
Sbjct: 73 IMNMIKLYGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130
Query: 130 VVC---DENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK 186
+ D SKGYAF++F + +A+D AIE MNG L +R + V + +K+ + E
Sbjct: 131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVS-YAFKKDSKGERHGS 189
Query: 187 AKE 189
A E
Sbjct: 190 AAE 192
Score = 87.8 bits (216), Expect = 3e-17
Identities = 57/186 (30%), Positives = 98/186 (52%), Gaps = 21/186 (11%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
VY+ E+V + L ELF Q G ++ + +D G+ +G+GFV + EDA+ A++ M
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
N ++ GK I V +A + ++ G N++I NLD ID++ L
Sbjct: 75 NMIKLYGKPIRVNKASAH-NKNLDV----------------GANIFIGNLDPEIDEKLLY 117
Query: 312 KEFSPFGSITSAKVMLED---GRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
FS FG I ++ D G SKG+ F+ F+S + + A+ MNG+ + ++P+ V+ A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
Query: 369 QRKEER 374
+K+ +
Sbjct: 178 FKKDSK 183
Score = 87.0 bits (214), Expect = 5e-17
Identities = 56/183 (30%), Positives = 98/183 (53%), Gaps = 11/183 (6%)
Query: 91 PSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQ 148
P ++ V++ LD+ + L++ F G +++ + D +GY FV F ++
Sbjct: 5 PISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSE 64
Query: 149 EAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLK 208
E AD AI+ MN + L + + V + S + ++GA N++I N E+D++ L
Sbjct: 65 EDADYAIKIMNMIKLYGKPIRVNK-ASAHNKNLDVGA------NIFIGNLDPEIDEKLLY 117
Query: 209 ELFSQFGKTLSV-KVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
+ FS FG L K+MRDP+ G SKG+ F+++ + ++ A+E MNG+ + + I V A
Sbjct: 118 DTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177
Query: 267 QKK 269
KK
Sbjct: 178 FKK 180
>gi|239753150 PREDICTED: similar to poly(A) binding protein,
cytoplasmic 1 [Homo sapiens]
Length = 94
Score = 124 bits (312), Expect = 2e-28
Identities = 70/87 (80%), Positives = 75/87 (86%), Gaps = 3/87 (3%)
Query: 558 MLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVD 617
MLA+APPQEQK++LGERLFPLIQ MH LAGKITGM LE DNSELLHMLESPESL SKV
Sbjct: 1 MLASAPPQEQKRILGERLFPLIQAMHPTLAGKITGMWLETDNSELLHMLESPESLHSKVV 60
Query: 618 EAVAVLQAHHAKKEAAQKVGAVAAATS 644
EAVAVLQAH A KEAAQK AV +AT+
Sbjct: 61 EAVAVLQAHRA-KEAAQK--AVNSATA 84
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 115 bits (287), Expect = 2e-25
Identities = 70/270 (25%), Positives = 133/270 (49%), Gaps = 16/270 (5%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 161 MLLNDRKVFVGRFKSRKEREAELGA-------KAKEFTNVYIKNFGEEVDDESLKELFSQ 213
+ ++V V + ++ + + ++++ +V++ + E+ E +K F+
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAP 128
Query: 214 FGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER 272
FG+ +V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K
Sbjct: 129 FGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPA 188
Query: 273 -QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE 328
++ + +QL + + S +Y + + ++ +R+ FSPFG I +V +
Sbjct: 189 PKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD 248
Query: 329 DGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
KG+ FV F+S E A A+ +NG +
Sbjct: 249 ----KGYSFVRFNSHESAAHAIVSVNGTTI 274
Score = 107 bits (266), Expect = 4e-23
Identities = 78/279 (27%), Positives = 126/279 (45%), Gaps = 36/279 (12%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVG-------------NVFIKNLDKSIDNKALYDT 118
MN I GK +++ W+ S +K +VF+ +L I + +
Sbjct: 66 MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAA 125
Query: 119 FSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRF 173
F+ FG I +VV D SKGY FV F + A+ AI++M G L R++ + R
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
Query: 174 KSRKEREAELGAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKV 222
+ E K + VY + ++ +++ FS FG+ + ++V
Sbjct: 186 PPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRV 245
Query: 223 MRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
D KG+ FV + HE A A+ +NG I G ++
Sbjct: 246 FPD-----KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
Score = 84.7 bits (208), Expect = 2e-16
Identities = 51/181 (28%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
G++I GK + V A ++ + Q + ++++ +L I E ++
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHF---HVFVGDLSPEITTEDIKA 124
Query: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 125 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 184
Query: 371 K 371
K
Sbjct: 185 K 185
Score = 46.6 bits (109), Expect = 7e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 209 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 262
Query: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
A+ ++N I+G ++ W +
Sbjct: 263 AHAIVSVNGTTIEGHVVKCYWGK 285
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 114 bits (284), Expect = 4e-25
Identities = 73/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
+++ NL + + + FS G SCK++ + + Y FV F A A+ MNG
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
Query: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
+ ++V V + ++ + +V++ + E+ E +K F+ FGK
Sbjct: 71 RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
Query: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
+V++D GKSKG+GFVS+ DA A+ M G+ + G+ I A +K ++ +
Sbjct: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
Query: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
+QL+ E + S + +Y + + D+ +R+ FSPFG I +V E KG+
Sbjct: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
FV FS+ E A A+ +NG +
Sbjct: 243 SFVRFSTHESAAHAIVSVNGTTI 265
Score = 113 bits (283), Expect = 5e-25
Identities = 83/271 (30%), Positives = 126/271 (46%), Gaps = 31/271 (11%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
+LYVG+L DVTE ++ + FS GP S + MIT + Y +V F + DA AL
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
Query: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNIL 126
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
Query: 127 SCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREA 181
+VV D SKGY FV F + A+ AI M G L R++ + R +
Sbjct: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
Query: 182 ELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKS 230
E K F + VY + D+ +++ FS FG+ + ++V +
Sbjct: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
Query: 231 KGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
KG+ FV + HE A A+ +NG I G ++
Sbjct: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
Score = 84.0 bits (206), Expect = 4e-16
Identities = 51/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
+Y+ N +V + + +LFSQ G S K++ + + FV + +H DA A+ MN
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
Query: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 70 GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115
Query: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ M G+ +G + + A R
Sbjct: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
Query: 371 K 371
K
Sbjct: 176 K 176
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
SS ++Y G + S +T+ ++ + FSP G ++ IRV + GY++V F A
Sbjct: 200 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 253
Query: 66 ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
A+ ++N I+G ++ W + P + K+
Sbjct: 254 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 114 bits (284), Expect = 4e-25
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 13/263 (4%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
+++ NL + + + FS G +CK++ D G+ Y FV F A A+ MNG
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
+ ++V V + ++ + +V++ + E+ E +K F+ FG+
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
+V++D GKSKG+GFVS+ DA A+++M G+ + G+ I A +K ++ +
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
Query: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
+QL + + S +Y + + ++ +R+ FSPFG I +V + KG+
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD----KGY 240
Query: 336 GFVCFSSPEEATKAVTEMNGRIV 358
FV F+S E A A+ +NG +
Sbjct: 241 SFVRFNSHESAAHAIVSVNGTTI 263
Score = 112 bits (280), Expect = 1e-24
Identities = 80/269 (29%), Positives = 127/269 (47%), Gaps = 27/269 (10%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+LYVG+L DVTEA++ + FS GP + ++ D T + Y +V F + A AL
Sbjct: 8 TLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAA 65
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNILSC 128
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 66 MNGRKIMGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDA 124
Query: 129 KVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREAEL 183
+VV D SKGY FV F + A+ AI++M G L R++ + R + E
Sbjct: 125 RVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYES 184
Query: 184 GAKAKEF-----------TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKG 232
K + VY + ++ +++ FS FG+ + ++V D KG
Sbjct: 185 NTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD-----KG 239
Query: 233 FGFVSYEKHEDANKAVEEMNGKEISGKII 261
+ FV + HE A A+ +NG I G ++
Sbjct: 240 YSFVRFNSHESAAHAIVSVNGTTIEGHVV 268
Score = 84.7 bits (208), Expect = 2e-16
Identities = 51/181 (28%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
+Y+ N +V + + +LFSQ G + K++ D G + FV + +H A A+ MN
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKA 113
Query: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ +M G+ +G + + A R
Sbjct: 114 AFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATR 173
Query: 371 K 371
K
Sbjct: 174 K 174
Score = 46.6 bits (109), Expect = 7e-05
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
SS ++Y G + S +TE ++ + FSP G ++ IRV D GY++V F A
Sbjct: 198 SSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESA 251
Query: 66 ERALDTMNFDVIKGKPIRIMWSQ 88
A+ ++N I+G ++ W +
Sbjct: 252 AHAIVSVNGTTIEGHVVKCYWGK 274
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 113 bits (283), Expect = 5e-25
Identities = 97/358 (27%), Positives = 170/358 (47%), Gaps = 34/358 (9%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSP--AGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
+L+VG+L+ + + L S A L++ R +TR+ + YV+F+ D E+AL
Sbjct: 308 NLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRK---FGYVDFESAEDLEKAL 364
Query: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
+ V G I++ + S ++ + KNL + L + F I +
Sbjct: 365 ELTGLKVF-GNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI---R 420
Query: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAK--- 186
+V + SKG A++ F+T+ A+K E+ G ++ R + + + + + G K
Sbjct: 421 LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST 480
Query: 187 -AKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
+ E + + N +E+L+E+F K +KV ++ NGKSKG+ F+ + EDA
Sbjct: 481 WSGESKTLVLSNLSYSATEETLQEVFE---KATFIKVPQNQNGKSKGYAFIEFASFEDAK 537
Query: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
+A+ N +EI G+ I ++E Q + + + L++K L +
Sbjct: 538 EALNSCNKREIEGRAI-------RLELQGPRGSPNARSQPSK-------TLFVKGLSEDT 583
Query: 306 DDEKLRKEFSPFGSITSAKVM-LEDGRSKGFGFVCFSSPEEATKAVTEM-NGRIVGSK 361
+E L++ F GS+ + V E G SKGFGFV F+S E+A A M +G I G+K
Sbjct: 584 TEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNK 639
Score = 83.6 bits (205), Expect = 5e-16
Identities = 79/274 (28%), Positives = 123/274 (44%), Gaps = 31/274 (11%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L +L VT+ L E F A + V +D +S G AY+ F+ ADAE+ +
Sbjct: 394 TLLAKNLPYKVTQDELKEVFEDAAEIRL--VSKD---GKSKGIAYIEFKTEADAEKTFEE 448
Query: 72 MNFDVIKGKPIRIMWS-QRDPSLRKSGVGN---------VFIKNLDKSIDNKALYDTFSA 121
I G+ I + ++ ++ + G N + + NL S + L + F
Sbjct: 449 KQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEK 508
Query: 122 FGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKERE 180
I KV ++NG SKGYAF+ F + E A +A+ N + R + R E +
Sbjct: 509 ATFI---KVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAI-------RLELQ 558
Query: 181 AELG---AKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVS 237
G A+++ +++K E+ +E+LKE F G + V G SKGFGFV
Sbjct: 559 GPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVD 616
Query: 238 YEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVE 271
+ EDA A E M EI G + + A+ K E
Sbjct: 617 FNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGE 650
Score = 76.3 bits (186), Expect = 8e-14
Identities = 63/234 (26%), Positives = 110/234 (47%), Gaps = 25/234 (10%)
Query: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIK 196
++ + +V FE+ E +KA+E L KVF K K + + K ++ + K
Sbjct: 346 TRKFGYVDFESAEDLEKALE------LTGLKVFGNEIKLEKPKGKD-SKKERDARTLLAK 398
Query: 197 NFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEI 256
N +V + LKE+F + V +GKSKG ++ ++ DA K EE G EI
Sbjct: 399 NLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQGTEI 454
Query: 257 SGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN--LYIKNLDDTIDDEKLRKEF 314
G+ I + +K + Q + + S + G + L + NL + +E L++ F
Sbjct: 455 DGRSISLYYTGEKGQNQ--------DYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVF 506
Query: 315 SPFGSITSAKV-MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVAL 367
T KV ++G+SKG+ F+ F+S E+A +A+ N R + + + + L
Sbjct: 507 E---KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLEL 557
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 5 ASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPAD 64
A S P +L+V L D TE L E F + + R+ D T S G+ +V+F D
Sbjct: 566 ARSQPSKTLFVKGLSEDTTEETLKESFDGS---VRARIVTDRETGSSKGFGFVDFNSEED 622
Query: 65 AERALDTMNFDVIKGKPIRIMWSQ 88
A+ A + M I G + + W++
Sbjct: 623 AKAAKEAMEDGEIDGNKVTLDWAK 646
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 112 bits (279), Expect = 1e-24
Identities = 81/318 (25%), Positives = 149/318 (46%), Gaps = 49/318 (15%)
Query: 97 GVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKA 154
G N+ + L +++ L FS+ G + S K++ D+ S GY FV++ T + A++A
Sbjct: 18 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERA 77
Query: 155 IEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQF 214
I +NG+ L + + K A ++ + N+YI + + ++++FS+F
Sbjct: 78 INTLNGLRLQSKTI--------KVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRF 129
Query: 215 GKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGK-----IIFVGRAQK 268
G+ ++ +V+ D G S+G F+ ++K +A +A+ NG + G + F +
Sbjct: 130 GRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQ 189
Query: 269 K--------------------VERQAELKRKFEQLKQERISRYQGVN----------LYI 298
V QA+ + +F + + +S GVN ++I
Sbjct: 190 NKNVALLSQLYHSPARRFGGPVHHQAQ-RFRFSPMGVDHMSGLSGVNVPGNASSGWCIFI 248
Query: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
NL D+ L + F PFG++T+ KV+ + + KGFGFV ++ EEA A+ +NG
Sbjct: 249 YNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308
Query: 357 IVGSKPLYVALAQRKEER 374
+G K L V+ K +
Sbjct: 309 RLGDKILQVSFKTNKSHK 326
Score = 100 bits (250), Expect = 3e-21
Identities = 80/300 (26%), Positives = 136/300 (45%), Gaps = 51/300 (17%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ L FS G V S ++ RD + SLGY +VN+ DAERA++T
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N++I L +++ K + D FS FG I++ +V+
Sbjct: 81 LNGLRLQSKTIKVSYAR--PSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138
Query: 132 CDENG--SKGYAFVHFETQEAADKAIEKMNG-MLLNDRKVFVGRFKSRKEREAELGAKAK 188
D+ S+G AF+ F+ + A++AI NG + +F + + + A
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNV-ALLS 197
Query: 189 EFTNVYIKNFGEEVDDESLKELFSQFG--------------------------------- 215
+ + + FG V ++ + FS G
Sbjct: 198 QLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADE 257
Query: 216 -----------KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
+VKV+RD N K KGFGFV+ +E+A A+ +NG + KI+ V
Sbjct: 258 GILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317
Score = 83.6 bits (205), Expect = 5e-16
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 23/190 (12%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + + L+ LFS G+ S K++RD G S G+GFV+Y +DA +A+
Sbjct: 20 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 79
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ E + NLYI L T+ +
Sbjct: 80 TLNGLRLQSKTIKVSYARPSSE------------------VIKDANLYISGLPRTMTQKD 121
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
+ FS FG I +++V+++ G S+G F+ F EA +A+T NG S+P+ V
Sbjct: 122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITV 181
Query: 366 ALAQRKEERK 375
A + K
Sbjct: 182 KFAANPNQNK 191
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 111 bits (278), Expect = 2e-24
Identities = 87/378 (23%), Positives = 172/378 (45%), Gaps = 66/378 (17%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DA++A++T
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K + FS +G I++ +++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
D+ S+G F+ F+ + A++AI+ +NG + LGA
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG-------------------QKPLGA---- 194
Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
+ ++VK +P+ K+ G +++ A +
Sbjct: 195 -------------------------AEPITVKFANNPSQKT-GQALLTHLYQSSARRYAG 228
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL-----------YI 298
++ + ++ + V+ L +F + + +S GV L ++
Sbjct: 229 PLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFV 288
Query: 299 KNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGR 356
NL D+ L + F PFG++T+ KV+ + + KGFGFV ++ +EA A+ +NG
Sbjct: 289 YNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGY 348
Query: 357 IVGSKPLYVALAQRKEER 374
+G + L V+ K+ +
Sbjct: 349 RLGERVLQVSFKTSKQHK 366
Score = 84.7 bits (208), Expect = 2e-16
Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 28/215 (13%)
Query: 184 GAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHE 242
GA TN+ + + + + K LF G S K++RD G+S G+GFV+Y
Sbjct: 32 GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPN 91
Query: 243 DANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLD 302
DA+KA+ +NG ++ K I V A+ + + NLY+ L
Sbjct: 92 DADKAINTLNGLKLQTKTIKVSYARPS------------------SASIRDANLYVSGLP 133
Query: 303 DTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IV 358
T+ +++ + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ +
Sbjct: 134 KTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 193
Query: 359 GSKPLYVALAQRKEERK-----AHLTNQYMQRVAG 388
++P+ V A ++ HL +R AG
Sbjct: 194 AAEPITVKFANNPSQKTGQALLTHLYQSSARRYAG 228
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L +R + V FK+ K+ +A
Sbjct: 346 NGYRLGERVLQVS-FKTSKQHKA 367
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 110 bits (275), Expect = 4e-24
Identities = 83/330 (25%), Positives = 153/330 (46%), Gaps = 65/330 (19%)
Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
N+ + L +++ F + G+I SCK+V D+ S GY FV++ ADKAI
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
+NG+ L + KV R S R+A N+Y+ + + + +++LFSQ+G
Sbjct: 100 LNGLKLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMSQKEMEQLFSQYG 149
Query: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269
+ ++ +++ D G S+G GF+ ++K +A +A++ +NG++ G + F +K
Sbjct: 150 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQK 209
Query: 270 VER-------QAELKR-------------------------KFEQLKQERISRYQGVNL- 296
+ Q+ +R +F + + +S GV L
Sbjct: 210 TGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLS 269
Query: 297 ----------YIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPE 344
++ NL D+ L + F PFG++T+ KV+ + + KGFGFV ++ +
Sbjct: 270 GGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYD 329
Query: 345 EATKAVTEMNGRIVGSKPLYVALAQRKEER 374
EA A+ +NG +G + L V+ K+ +
Sbjct: 330 EAAMAIASLNGYRLGERVLQVSFKTSKQHK 359
Score = 85.9 bits (211), Expect = 1e-16
Identities = 45/151 (29%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DA++A++T
Sbjct: 40 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 99
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K + FS +G I++ +++
Sbjct: 100 LNGLKLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRIL 157
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160
D+ S+G F+ F+ + A++AI+ +NG
Sbjct: 158 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 84.7 bits (208), Expect = 2e-16
Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 28/215 (13%)
Query: 184 GAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHE 242
GA TN+ + + + + K LF G S K++RD G+S G+GFV+Y
Sbjct: 32 GATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPN 91
Query: 243 DANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLD 302
DA+KA+ +NG ++ K I V A+ + + NLY+ L
Sbjct: 92 DADKAINTLNGLKLQTKTIKVSYARPS------------------SASIRDANLYVSGLP 133
Query: 303 DTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IV 358
T+ +++ + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ +
Sbjct: 134 KTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 193
Query: 359 GSKPLYVALAQRKEERK-----AHLTNQYMQRVAG 388
++P+ V A ++ HL +R AG
Sbjct: 194 AAEPITVKFANNPSQKTGQALLTHLYQSSARRYAG 228
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L +R + V FK+ K+ +A
Sbjct: 339 NGYRLGERVLQVS-FKTSKQHKA 360
Score = 40.0 bits (92), Expect = 0.007
Identities = 17/61 (27%), Positives = 35/61 (57%)
Query: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L + E++L++ F P G V +++V RD T + G+ +V +A A+ ++
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 73 N 73
N
Sbjct: 339 N 339
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 110 bits (274), Expect = 5e-24
Identities = 83/329 (25%), Positives = 155/329 (47%), Gaps = 64/329 (19%)
Query: 100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEK 157
N+ + L +++ + L F + G I SCK+V D+ S GY FV++ + A+KAI
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
+NG+ L + KV R S R+A N+Y+ + + + L++LFSQ+G
Sbjct: 100 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 149
Query: 216 KTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEISG-----KIIFVGRAQKK 269
+ ++ +++ D G S+G GF+ ++K +A +A++ +NG++ G + F +K
Sbjct: 150 RIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQK 209
Query: 270 --------------------VERQAELKR------------KFEQLKQERISRYQGVN-- 295
+ +QA+ R +F + + ++ G+N
Sbjct: 210 TNQAILSQLYQSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIP 269
Query: 296 --------LYIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEE 345
+++ NL D+ L + F PFG++T+ KV+ + KGFGFV ++ +E
Sbjct: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
Query: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEER 374
A A+ +NG +G + L V+ K +
Sbjct: 330 AAMAIASLNGYRLGDRVLQVSFKTNKTHK 358
Score = 87.8 bits (216), Expect = 3e-17
Identities = 48/151 (31%), Positives = 89/151 (58%), Gaps = 4/151 (2%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ L F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 100 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 157
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNG 160
D+ S+G F+ F+ + A++AI+ +NG
Sbjct: 158 VDQVTGISRGVGFIRFDKRIEAEEAIKGLNG 188
Score = 82.8 bits (203), Expect = 9e-16
Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 27/196 (13%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + E LK LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 39 TNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 98
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 99 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 140
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGRIV--GSKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 141 LEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITV 200
Query: 366 ALAQRKEERKAHLTNQ 381
A ++ TNQ
Sbjct: 201 KFANNPSQK----TNQ 212
Score = 47.4 bits (111), Expect = 4e-05
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K +A
Sbjct: 338 NGYRLGDRVLQVS-FKTNKTHKA 359
Score = 40.8 bits (94), Expect = 0.004
Identities = 18/61 (29%), Positives = 35/61 (57%)
Query: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++V +L D E++L++ F P G V +++V RD T + G+ +V +A A+ ++
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 73 N 73
N
Sbjct: 338 N 338
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 109 bits (273), Expect = 7e-24
Identities = 81/284 (28%), Positives = 126/284 (44%), Gaps = 40/284 (14%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG---------------YAY 56
+LYVG+L DVTE ++ + FS GP S ++ + R + Y +
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69
Query: 57 VNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNK 113
V F + DA AL MN I GK +++ W+ PS +K N VF+ +L I +
Sbjct: 70 VEFYEHRDAAAALAAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTE 128
Query: 114 ALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV--- 168
+ F+ FG I +VV D SKGY FV F + A+ AI M G L R++
Sbjct: 129 DIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTN 188
Query: 169 FVGRFKSRKEREAELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKT 217
+ R + E K F + VY + D+ +++ FS FG+
Sbjct: 189 WATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQI 248
Query: 218 LSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
+ ++V + KG+ FV + HE A A+ +NG I G ++
Sbjct: 249 MEIRVFPE-----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 287
Score = 105 bits (263), Expect = 1e-22
Identities = 76/280 (27%), Positives = 130/280 (46%), Gaps = 30/280 (10%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE------NGSKG-----------YAFV 143
+++ NL + + + FS G SCK++ ++ N S G Y FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 144 HFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVD 203
F A A+ MNG + ++V V + ++ + +V++ + E+
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEIT 126
Query: 204 DESLKELFSQFGKTLSVKVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262
E +K F+ FGK +V++D GKSKG+GFVS+ DA A+ M G+ + G+ I
Sbjct: 127 TEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIR 186
Query: 263 VGRAQKKVER-QAELKRKFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFG 318
A +K ++ + +QL+ E + S + +Y + + D+ +R+ FSPFG
Sbjct: 187 TNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFG 246
Query: 319 SITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIV 358
I +V E KG+ FV FS+ E A A+ +NG +
Sbjct: 247 QIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTI 282
Score = 80.1 bits (196), Expect = 6e-15
Identities = 55/197 (27%), Positives = 96/197 (48%), Gaps = 32/197 (16%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRD-PNGK----SKGFG-----------FV 236
+Y+ N +V + + +LFSQ G S K++ + P+ + S GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL 296
+ +H DA A+ MNG++I GK + V A ++ + F ++
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHF--------------HV 116
Query: 297 YIKNLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMN 354
++ +L I E ++ F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ M
Sbjct: 117 FVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMG 176
Query: 355 GRIVGSKPLYVALAQRK 371
G+ +G + + A RK
Sbjct: 177 GQWLGGRQIRTNWATRK 193
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
SS ++Y G + S +T+ ++ + FSP G ++ IRV + GY++V F A
Sbjct: 217 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 270
Query: 66 ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
A+ ++N I+G ++ W + P + K+
Sbjct: 271 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 301
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 108 bits (271), Expect = 1e-23
Identities = 89/377 (23%), Positives = 163/377 (43%), Gaps = 58/377 (15%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200
Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
T F +S + L SQ + + PN + G H A +
Sbjct: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQA----Q 242
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN----------LYIK 299
+ V R + +F + + ++ G+N +++
Sbjct: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
Query: 358 VGSKPLYVALAQRKEER 374
+G + L V+ K +
Sbjct: 363 LGDRVLQVSFKTNKAHK 379
Score = 80.1 bits (196), Expect = 6e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEERKA 376
A ++ +
Sbjct: 208 KFANNPSQKSS 218
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 107 bits (268), Expect = 3e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 110 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 167
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 168 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 203
Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
T F +S + L SQ + + PN + G H A +
Sbjct: 204 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 247
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
R + +KR F + + ++ G+N+ ++
Sbjct: 248 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 291
Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 292 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 351
Query: 358 VGSKPLYVALAQRKEER 374
+G + L V+ K +
Sbjct: 352 LGDRVLQVSFKTNKAHK 368
Score = 80.1 bits (196), Expect = 6e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 49 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 108
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 109 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 150
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 151 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 210
Query: 366 ALAQRKEERKA 376
A ++ +
Sbjct: 211 KFANNPSQKSS 221
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 348 NGYRLGDRVLQVS-FKTNKAHKS 369
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 107 bits (268), Expect = 3e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200
Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
T F +S + L SQ + + PN + G H A +
Sbjct: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 244
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
R + +KR F + + ++ G+N+ ++
Sbjct: 245 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 288
Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 289 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 348
Query: 358 VGSKPLYVALAQRKEER 374
+G + L V+ K +
Sbjct: 349 LGDRVLQVSFKTNKAHK 365
Score = 80.1 bits (196), Expect = 6e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEERKA 376
A ++ +
Sbjct: 208 KFANNPSQKSS 218
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 107 bits (268), Expect = 3e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 217
Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
T F +S + L SQ + + PN + G H A +
Sbjct: 218 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 261
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
R + +KR F + + ++ G+N+ ++
Sbjct: 262 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305
Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365
Query: 358 VGSKPLYVALAQRKEER 374
+G + L V+ K +
Sbjct: 366 LGDRVLQVSFKTNKAHK 382
Score = 80.1 bits (196), Expect = 6e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
Query: 366 ALAQRKEERKA 376
A ++ +
Sbjct: 225 KFANNPSQKSS 235
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 107 bits (268), Expect = 3e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
Query: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200
Query: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
T F +S + L SQ + + PN + G H A +
Sbjct: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 244
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
R + +KR F + + ++ G+N+ ++
Sbjct: 245 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 288
Query: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 289 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 348
Query: 358 VGSKPLYVALAQRKEER 374
+G + L V+ K +
Sbjct: 349 LGDRVLQVSFKTNKAHK 365
Score = 80.1 bits (196), Expect = 6e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
Query: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
Query: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
Query: 366 ALAQRKEERKA 376
A ++ +
Sbjct: 208 KFANNPSQKSS 218
Score = 46.2 bits (108), Expect = 9e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 159 NGMLLNDRKVFVGRFKSRKEREA 181
NG L DR + V FK+ K ++
Sbjct: 345 NGYRLGDRVLQVS-FKTNKAHKS 366
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 106 bits (265), Expect = 6e-23
Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)
Query: 60 QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118
QQ + + A TM F D + P++ M +QR +L + + V++ ++ + +
Sbjct: 50 QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 105
Query: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
F+ FG I S + D KG+AFV +E EAA A+E+MN ++L R + VGR +
Sbjct: 106 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 165
Query: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232
+ + +L +A+ F +Y+ + +++ D+ +K +F FGK S + RDP GK KG
Sbjct: 166 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 225
Query: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
+GF+ YEK + + AV MN ++ G+ + VG+A
Sbjct: 226 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 259
Score = 79.3 bits (194), Expect = 1e-14
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)
Query: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
M +YVG ++ ++ E + + F+P GP+ SI + D +T + G+A+V ++ P A+ AL
Sbjct: 85 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 144
Query: 70 DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
+ MN ++ G+ I++ Q P + +++ ++ + + + + F
Sbjct: 145 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 204
Query: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
AFG I SC + D KGY F+ +E +++ A+ MN L + + VG+
Sbjct: 205 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 258
Score = 77.4 bits (189), Expect = 4e-14
Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
VY+ + E+ ++++++ F+ FG S+ + D K KGF FV YE E A A+E+M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
N + G+ I VGR AQ +++ AE R F + +Y+ ++ +
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 194
Query: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363
D+ ++ F FG I S + + G+ KG+GF+ + + + AV+ MN +G + L
Sbjct: 195 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 254
Query: 364 YVALA 368
V A
Sbjct: 255 RVGKA 259
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 106 bits (265), Expect = 6e-23
Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)
Query: 60 QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118
QQ + + A TM F D + P++ M +QR +L + + V++ ++ + +
Sbjct: 93 QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148
Query: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176
F+ FG I S + D KG+AFV +E EAA A+E+MN ++L R + VGR +
Sbjct: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208
Query: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232
+ + +L +A+ F +Y+ + +++ D+ +K +F FGK S + RDP GK KG
Sbjct: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268
Query: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
+GF+ YEK + + AV MN ++ G+ + VG+A
Sbjct: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
Score = 79.3 bits (194), Expect = 1e-14
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)
Query: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
M +YVG ++ ++ E + + F+P GP+ SI + D +T + G+A+V ++ P A+ AL
Sbjct: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
Query: 70 DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
+ MN ++ G+ I++ Q P + +++ ++ + + + + F
Sbjct: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
Query: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
AFG I SC + D KGY F+ +E +++ A+ MN L + + VG+
Sbjct: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
Score = 77.4 bits (189), Expect = 4e-14
Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)
Query: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251
VY+ + E+ ++++++ F+ FG S+ + D K KGF FV YE E A A+E+M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305
N + G+ I VGR AQ +++ AE R F + +Y+ ++ +
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
Query: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363
D+ ++ F FG I S + + G+ KG+GF+ + + + AV+ MN +G + L
Sbjct: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 297
Query: 364 YVALA 368
V A
Sbjct: 298 RVGKA 302
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 102 bits (254), Expect = 1e-21
Identities = 56/172 (32%), Positives = 96/172 (55%), Gaps = 6/172 (3%)
Query: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
V++ ++ + + F+ FG I S + D KG+AFV +E EAA A+E+M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
N ++L R + VGR + + + +L +A+ F +Y+ + +++ D+ +K +F FG
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 216 KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
K S + RDP GK KG+GF+ YEK + + AV MN ++ G+ + VG+A
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
Score = 79.3 bits (194), Expect = 1e-14
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)
Query: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
M +YVG ++ ++ E + + F+P GP+ SI + D +T + G+A+V ++ P A+ AL
Sbjct: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
Query: 70 DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
+ MN ++ G+ I++ Q P + +++ ++ + + + + F
Sbjct: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
Query: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
AFG I SC + D KGY F+ +E +++ A+ MN L + + VG+
Sbjct: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/239 (26%), Positives = 115/239 (48%), Gaps = 31/239 (12%)
Query: 146 ETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGAKAKE----FTNVYIKNF 198
E QEA KA K M + + V V + + ++++ ++ A+ + VY+ +
Sbjct: 62 EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119
Query: 199 GEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEIS 257
E+ ++++++ F+ FG S+ + D K KGF FV YE E A A+E+MN +
Sbjct: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179
Query: 258 GKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
G+ I VGR AQ +++ AE R F + +Y+ ++ + D+ ++
Sbjct: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226
Query: 312 KEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
F FG I S + + G+ KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 93.6 bits (231), Expect = 5e-19
Identities = 74/286 (25%), Positives = 142/286 (49%), Gaps = 25/286 (8%)
Query: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
++VG + D+ E L F AGP+ +R+ D +T + GYA+V F A+ A+
Sbjct: 164 IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLY 223
Query: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
N ++ GK I + S + L F+ ++ KS + + + FS L+ ++
Sbjct: 224 NNHEIRSGKHIGVCISVANNRL--------FVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
Query: 132 C----DENGSKGYAFVHFETQEAADKAIEK-MNGMLLNDRKVFVGRFKSR-KEREAELGA 185
D+ ++G+ F+ +E + A +A + M+G + V + ++ + E+ A
Sbjct: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMA 335
Query: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDAN 245
K K ++++N V +E L++ FSQFGK VK ++D + F+ +++ + A
Sbjct: 336 KVKV---LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD-------YAFIHFDERDGAV 385
Query: 246 KAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRY 291
KA+EEMNGK++ G+ I + A+ +++ E K + + K + Y
Sbjct: 386 KAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDY 431
Score = 80.5 bits (197), Expect = 4e-15
Identities = 78/310 (25%), Positives = 144/310 (46%), Gaps = 49/310 (15%)
Query: 79 GKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NG 136
G P ++S + PS+ +F+ + + + L F G I +++ D
Sbjct: 146 GPPPDSVYSGQQPSVGTE----IFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGL 201
Query: 137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTN-VYI 195
++GYAFV F T+EAA +A++ L N+ ++ G+ +G N +++
Sbjct: 202 NRGYAFVTFCTKEAAQEAVK-----LYNNHEIRSGK---------HIGVCISVANNRLFV 247
Query: 196 KNFGEEVDDESLKELFSQFGKTLSVKVMR---DPNGKSKGFGFVSYEKHEDANKAVEE-M 251
+ + E + E FS+ + L+ ++ D K++GF F+ YE H+ A +A M
Sbjct: 248 GSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLM 307
Query: 252 NGK-EISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKL 310
+GK ++ G + V A + E+ K + L +++NL +T+ +E L
Sbjct: 308 SGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVL-------------FVRNLANTVTEEIL 354
Query: 311 RKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA-- 368
K FS FG + K + K + F+ F + A KA+ EMNG+ + + + + A
Sbjct: 355 EKAFSQFGKLERVK------KLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKP 408
Query: 369 --QRKEERKA 376
Q+++ERKA
Sbjct: 409 PDQKRKERKA 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,685,833
Number of Sequences: 37866
Number of extensions: 1271055
Number of successful extensions: 7396
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 5120
Number of HSP's gapped (non-prelim): 1367
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.