Guide to the Human Genome
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Name: GDNF Sequence: fasta or formatted (211aa) NCBI GI: 4503975
Description:

glial cell derived neurotrophic factor isoform 1 preproprotein

Referenced in:

Neurons
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [185aa] glial cell derived neurotrophic factor isoform 2 precursor
alt prot [133aa] glial cell derived neurotrophic factor isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.5         20           4
 C cysteine            3.8          8           2
 D aspartate           8.5         18           3
 E glutamate           4.3          9           2
 F phenylalanine       3.3          7           1
 G glycine             5.7         12           1
 H histidine           1.9          4           1
 I isoleucine          3.8          8           1
 K lysine              6.2         13           1
 L leucine            10.0         21           2
 M methionine          1.9          4           1
 N asparagine          4.3          9           1
 P proline             5.7         12           2
 Q glutamine           2.8          6           1
 R arginine           10.9         23           3
 S serine              6.2         13           2
 T threonine           3.3          7           2
 V valine              5.2         11           2
 W tryptophan          0.5          1           1
 Y tyrosine            2.4          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glial cell derived neurotrophic factor isoform 1 prep... 
GDNF                  0.835   glial cell derived neurotrophic factor isoform 2 pre...
GDNF                  0.531   glial cell derived neurotrophic factor isoform 3 [Ho...
NRTN                  0.184   neurturin preproprotein 
ARTN                  0.108   neurotrophic factor artemin isoform 2 
ARTN                  0.108   neurotrophic factor artemin isoform 1 precursor [Ho...
ARTN                  0.108   neurotrophic factor artemin isoform 3 precursor [Ho...
ARTN                  0.108   neurotrophic factor artemin isoform 1 precursor [Ho...
ARTN                  0.108   neurotrophic factor artemin isoform 3 precursor [Ho...
PSPN                  0.106   persephin precursor 
GDF2                  0.020   growth differentiation factor 2 
GDF5                  0.017   growth differentiation factor 5 preproprotein 
LOC729196             0.012   PREDICTED: similar to unc-93 homolog B1 (C. elegans...
LOC729196             0.012   PREDICTED: similar to unc-93 homolog B1 (C. elegans...
FILIP1                0.012   filamin A interacting protein 1 
ZNF335                0.010   zinc finger protein 335 
CHST12                0.010   carbohydrate sulfotransferase 12 
MMP21                 0.010   matrix metalloproteinase 21 preproprotein 
CACNG6                0.010   voltage-dependent calcium channel gamma-6 subunit is...
CACNG6                0.010   voltage-dependent calcium channel gamma-6 subunit is...
CACNG6                0.010   voltage-dependent calcium channel gamma-6 subunit is...
MRE11A                0.010   meiotic recombination 11 homolog A isoform 2 
MRE11A                0.010   meiotic recombination 11 homolog A isoform 1 
BCL7C                 0.010   B-cell CLL/lymphoma 7C 
CCDC80                0.010   steroid-sensitive protein 1 
CCDC80                0.010   steroid-sensitive protein 1 
GLP-1                 0.010   GATA like protein-1 
SCG2                  0.007   secretogranin II precursor 
GPR108                0.007   G protein-coupled receptor 108 isoform 1 
LRRC41                0.007   MUF1 protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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