Guide to the Human Genome
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Name: GDNF Sequence: fasta or formatted (133aa) NCBI GI: 40549413
Description:

glial cell derived neurotrophic factor isoform 3

Referenced in:

Neurons
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [185aa] glial cell derived neurotrophic factor isoform 2 precursor
alt prot [211aa] glial cell derived neurotrophic factor isoform 1 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.5         10           2
 C cysteine            6.8          9           2
 D aspartate           6.8          9           3
 E glutamate           3.8          5           2
 F phenylalanine       2.3          3           1
 G glycine             9.8         13           1
 H histidine           3.0          4           1
 I isoleucine          4.5          6           1
 K lysine              6.0          8           1
 L leucine            10.5         14           1
 M methionine          0.8          1           1
 N asparagine          5.3          7           1
 P proline             3.8          5           1
 Q glutamine           1.5          2           1
 R arginine           11.3         15           2
 S serine              5.3          7           1
 T threonine           3.8          5           2
 V valine              4.5          6           1
 W tryptophan          0.0          0           0
 Y tyrosine            3.0          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glial cell derived neurotrophic factor isoform 3 [Ho... 
GDNF                  0.844   glial cell derived neurotrophic factor isoform 2 pre...
GDNF                  0.844   glial cell derived neurotrophic factor isoform 1 prep...
NRTN                  0.293   neurturin preproprotein 
ARTN                  0.176   neurotrophic factor artemin isoform 2 
ARTN                  0.176   neurotrophic factor artemin isoform 1 precursor [Ho...
ARTN                  0.176   neurotrophic factor artemin isoform 3 precursor [Ho...
ARTN                  0.176   neurotrophic factor artemin isoform 1 precursor [Ho...
ARTN                  0.176   neurotrophic factor artemin isoform 3 precursor [Ho...
PSPN                  0.168   persephin precursor 
GDF2                  0.027   growth differentiation factor 2 
GDF5                  0.023   growth differentiation factor 5 preproprotein 
BMP3                  0.016   bone morphogenetic protein 3 preproprotein 
FBN3                  0.012   fibrillin 3 precursor 
MRE11A                0.008   meiotic recombination 11 homolog A isoform 2 
MRE11A                0.008   meiotic recombination 11 homolog A isoform 1 
C11orf17              0.008   chromosome 11 open reading frame 17 
C11orf17              0.008   chromosome 11 open reading frame 17 
CROCC                 0.004   ciliary rootlet coiled-coil 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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