Guide to the Human Genome
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Name: GDNF Sequence: fasta or formatted (185aa) NCBI GI: 40549411
Description:

glial cell derived neurotrophic factor isoform 2 precursor

Referenced in:

Neurons
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [133aa] glial cell derived neurotrophic factor isoform 3
alt prot [211aa] glial cell derived neurotrophic factor isoform 1 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.2         17           4
 C cysteine            4.3          8           2
 D aspartate           8.6         16           3
 E glutamate           3.8          7           2
 F phenylalanine       3.2          6           1
 G glycine             5.4         10           1
 H histidine           2.2          4           1
 I isoleucine          4.3          8           1
 K lysine              6.5         12           1
 L leucine            10.3         19           2
 M methionine          2.2          4           1
 N asparagine          4.9          9           1
 P proline             4.3          8           1
 Q glutamine           3.2          6           1
 R arginine            9.7         18           2
 S serine              4.9          9           1
 T threonine           3.8          7           2
 V valine              5.9         11           2
 W tryptophan          0.5          1           1
 Y tyrosine            2.7          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glial cell derived neurotrophic factor isoform 2 pre... 
GDNF                  0.955   glial cell derived neurotrophic factor isoform 1 prep...
GDNF                  0.607   glial cell derived neurotrophic factor isoform 3 [Ho...
NRTN                  0.211   neurturin preproprotein 
ARTN                  0.124   neurotrophic factor artemin isoform 2 
ARTN                  0.124   neurotrophic factor artemin isoform 1 precursor [Ho...
ARTN                  0.124   neurotrophic factor artemin isoform 3 precursor [Ho...
ARTN                  0.124   neurotrophic factor artemin isoform 1 precursor [Ho...
ARTN                  0.124   neurotrophic factor artemin isoform 3 precursor [Ho...
PSPN                  0.121   persephin precursor 
GDF2                  0.022   growth differentiation factor 2 
GDF5                  0.020   growth differentiation factor 5 preproprotein 
CACNG6                0.011   voltage-dependent calcium channel gamma-6 subunit is...
CACNG6                0.011   voltage-dependent calcium channel gamma-6 subunit is...
CACNG6                0.011   voltage-dependent calcium channel gamma-6 subunit is...
MRE11A                0.011   meiotic recombination 11 homolog A isoform 2 
MRE11A                0.011   meiotic recombination 11 homolog A isoform 1 
BCL7C                 0.011   B-cell CLL/lymphoma 7C 
CHST12                0.008   carbohydrate sulfotransferase 12 
GPR108                0.008   G protein-coupled receptor 108 isoform 1 
LOC643783             0.008   PREDICTED: hypothetical protein 
LOC643783             0.008   PREDICTED: hypothetical protein 
LOC643783             0.008   PREDICTED: hypothetical protein 
FBN3                  0.008   fibrillin 3 precursor 
USH1C                 0.006   harmonin isoform b3 
USH1C                 0.006   harmonin isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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