Guide to the Human Genome
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Name: GDF5 Sequence: fasta or formatted (501aa) NCBI GI: 4503969
Description:

growth differentiation factor 5 preproprotein

Referenced in:

TGF-beta Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         41           2
 C cysteine            2.0         10           2
 D aspartate           5.0         25           2
 E glutamate           5.4         27           1
 F phenylalanine       4.0         20           2
 G glycine             9.0         45           3
 H histidine           1.6          8           1
 I isoleucine          2.8         14           2
 K lysine              7.6         38           2
 L leucine            10.4         52           2
 M methionine          1.2          6           1
 N asparagine          2.8         14           2
 P proline             9.6         48           3
 Q glutamine           3.6         18           1
 R arginine            8.6         43           2
 S serine              5.8         29           2
 T threonine           4.8         24           1
 V valine              4.4         22           2
 W tryptophan          1.4          7           1
 Y tyrosine            2.0         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   growth differentiation factor 5 preproprotein 
GDF6                  0.313   growth differentiation factor 6 precursor 
GDF7                  0.254   growth differentiation factor 7 preproprotein 
BMP2                  0.128   bone morphogenetic protein 2 preproprotein 
BMP4                  0.126   bone morphogenetic protein 4 preproprotein 
BMP4                  0.126   bone morphogenetic protein 4 preproprotein 
BMP4                  0.126   bone morphogenetic protein 4 preproprotein 
BMP5                  0.123   bone morphogenetic protein 5 preproprotein 
BMP7                  0.114   bone morphogenetic protein 7 precursor 
BMP8B                 0.112   bone morphogenetic protein 8B preproprotein 
BMP8A                 0.112   bone morphogenetic protein 8A 
BMP6                  0.111   bone morphogenetic protein 6 preproprotein 
BMP10                 0.106   bone morphogenetic protein 10 preproprotein 
GDF2                  0.093   growth differentiation factor 2 
GDF3                  0.093   growth differentiation factor 3 precursor 
BMP3                  0.089   bone morphogenetic protein 3 preproprotein 
GDF1                  0.084   growth differentiation factor 1 
GDF10                 0.083   growth differentiation factor 10 precursor 
BMP15                 0.081   bone morphogenetic protein 15 precursor 
NODAL                 0.077   nodal precursor 
INHBA                 0.067   inhibin beta A precursor 
INHBE                 0.060   activin beta E 
MSTN                  0.058   myostatin 
GDF11                 0.057   growth differentiation factor 11 precursor 
GDF9                  0.055   growth differentiation factor 9 precursor 
INHBB                 0.055   inhibin beta B subunit preproprotein 
INHBC                 0.050   inhibin beta C chain preproprotein 
TGFB3                 0.047   transforming growth factor, beta 3 
TGFB2                 0.044   transforming growth factor, beta 2 isoform 1 
TGFB2                 0.044   transforming growth factor, beta 2 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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