Guide to the Human Genome
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Search of human proteins with 4503459

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa...   761   0.0  
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]         249   3e-66
gi|13540517 endothelial differentiation, sphingolipid G-protein-...   245   6e-65
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]         244   9e-65
gi|134244587 endothelial differentiation, sphingolipid G-protein...   205   5e-53
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]            181   8e-46
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           169   4e-42
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           169   4e-42
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]            161   1e-39
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]          119   6e-27
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]          119   6e-27
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]          119   6e-27
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]          119   6e-27
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]           119   6e-27
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]          119   6e-27
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                108   6e-24
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]         103   2e-22
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]                96   7e-20
gi|4885341 G protein-coupled receptor 6 [Homo sapiens]                 90   4e-18
gi|5921992 adenosine A2a receptor [Homo sapiens]                       82   1e-15
gi|5174535 melanocortin 5 receptor [Homo sapiens]                      81   2e-15
gi|71999131 opsin 3 [Homo sapiens]                                     74   2e-13
gi|4506527 rhodopsin [Homo sapiens]                                    73   5e-13
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]          72   6e-13
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]          72   6e-13
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]          72   6e-13
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]          72   6e-13
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]          72   6e-13
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]          72   6e-13
gi|119508433 melanocortin 4 receptor [Homo sapiens]                    72   1e-12

>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
           sapiens]
          Length = 384

 Score =  761 bits (1966), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV 60
           MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
Sbjct: 1   MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV 60

Query: 61  VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL 120
           VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
Sbjct: 61  VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL 120

Query: 121 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP 180
           REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
Sbjct: 121 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP 180

Query: 181 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP 240
           LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
Sbjct: 181 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP 240

Query: 241 AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS 300
           AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
Sbjct: 241 AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS 300

Query: 301 AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS 360
           AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
Sbjct: 301 AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS 360

Query: 361 FRGSRSLSFRMREPLSSISSVRSI 384
           FRGSRSLSFRMREPLSSISSVRSI
Sbjct: 361 FRGSRSLSFRMREPLSSISSVRSI 384


>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
          Length = 378

 Score =  249 bits (636), Expect = 3e-66
 Identities = 141/333 (42%), Positives = 196/333 (58%), Gaps = 5/333 (1%)

Query: 28  HYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVN 87
           HY + G+LAGR      G      L +     +VLENL+VL AI  + +    +Y+ + N
Sbjct: 21  HYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGN 80

Query: 88  ITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATM 147
           + L DLL G AY  N+L+SG +TF L+P  WFLREG +F AL AST SLL  A ER  TM
Sbjct: 81  LALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTM 140

Query: 148 VRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILF 207
           ++ +    A K  RV+  IG+CWL+A  LG LP+LGWNCL     CS++LPLYSK+YI F
Sbjct: 141 IK-MRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAF 199

Query: 208 CLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPL 267
           C+ IF  +L TI+ LY  I+ LV++S +K        ++  LL+TV++++  F+ CW PL
Sbjct: 200 CISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPL 259

Query: 268 FGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCL 327
           F L L DV    + A   L    W + LAVLNSA+NP+IY+  S+E+ RA    L C CL
Sbjct: 260 FILFLIDV-ACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFR-LVCNCL 317

Query: 328 RLGMRGPGDCLARAVE--AHSGASTTDSSLRPR 358
             G       +  A++      +S+ +SS  P+
Sbjct: 318 VRGRGARASPIQPALDPSRSKSSSSNNSSHSPK 350


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score =  245 bits (625), Expect = 6e-65
 Identities = 152/342 (44%), Positives = 198/342 (57%), Gaps = 22/342 (6%)

Query: 22  SRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWV 81
           S +IVLHYN++G+L G       GL A   + +A    +VLENL VL  +  H R    +
Sbjct: 12  SEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPM 71

Query: 82  YYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAG 141
           +  L ++TLSDLL GAAY AN+LLSG  T +L+PA WF REG +F AL AS  SLL  A 
Sbjct: 72  FLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIAL 131

Query: 142 ERFATMVR----PVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLL 197
           ER  TM R    PV+  G     R        W ++ LLG+LP LGWNCL   D CS++L
Sbjct: 132 ERSLTMARRGPAPVSSRG-----RTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVL 186

Query: 198 PLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAP-RPA--------ARRKAR- 247
           PLY+K Y+LFC++ F G+LA I  LY  I+  V+A+ ++ P RP         ARRK R 
Sbjct: 187 PLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRS 246

Query: 248 -RLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPII 306
             LL+T+ ++LLAF+ CWGPLF LLL DV          L+  D  L LA+ NS +NPII
Sbjct: 247 LALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQA-DPFLGLAMANSLLNPII 305

Query: 307 YSFRSREVCRAVLSFLCCGCLRLGMRGPG-DCLARAVEAHSG 347
           Y+  +R++  A+L  +CCG    G    G    A A EA  G
Sbjct: 306 YTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGG 347


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score =  244 bits (623), Expect = 9e-65
 Identities = 133/334 (39%), Positives = 199/334 (59%), Gaps = 11/334 (3%)

Query: 1   MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV 60
           M  T  P+       ++   +  +IV HYN++G+L      ++  +     + +   C +
Sbjct: 1   MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKL-NISADKENSIKLTSVVFILICCFI 59

Query: 61  VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL 120
           +LEN+ VL  I    +  R +YY + N+ LSDLL G AY AN+LLSGA T++L PAQWFL
Sbjct: 60  ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL 119

Query: 121 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP 180
           REG +F AL+AS FSLL  A ER+ TM++    +G +   R++  I  CW+++ +LG LP
Sbjct: 120 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNG-SNNFRLFLLISACWVISLILGGLP 178

Query: 181 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQK---- 236
           ++GWNC+ A   CS++LPLY K YILFC  +F  +L +I+ LY  I+ LV+   ++    
Sbjct: 179 IMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFR 238

Query: 237 ---APRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWIL 293
              +    +  K+  LLKTV+++L  F+ CW PLF LLL DV G  +   + L   ++ L
Sbjct: 239 KNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV-GCKVKTCDILFRAEYFL 297

Query: 294 ALAVLNSAVNPIIYSFRSREVCRAVLSFL-CCGC 326
            LAVLNS  NPIIY+  ++E+ RA +  + CC C
Sbjct: 298 VLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKC 331


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score =  205 bits (522), Expect = 5e-53
 Identities = 117/280 (41%), Positives = 170/280 (60%), Gaps = 6/280 (2%)

Query: 54  VAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRL 113
           V   C +V+ENLLVL A+  + +    +Y  L N+  SDLL G A++AN LLSG+ T RL
Sbjct: 41  VILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRL 100

Query: 114 APAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLA 173
            P QWF REG  F  L+AS FSLL  A ER   + + V   G+ K+ R+   IG  WL++
Sbjct: 101 TPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAK-VKLYGSDKSCRMLLLIGASWLIS 159

Query: 174 ALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQAS 233
            +LG LP+LGWNCL   + CS++LPLY+K Y+L  + IF+ +L  I+ LY  I+ +V++S
Sbjct: 160 LVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSS 219

Query: 234 GQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWIL 293
                 P    +   LLKTV ++L  F+VCW P F +LL D +   + +   L    +  
Sbjct: 220 HADMAAP----QTLALLKTVTIVLGVFIVCWLPAFSILLLD-YACPVHSCPILYKAHYFF 274

Query: 294 ALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRG 333
           A++ LNS +NP+IY++RSR++ R VL  L C    +G++G
Sbjct: 275 AVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQG 314


>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
          Length = 351

 Score =  181 bits (460), Expect = 8e-46
 Identities = 129/336 (38%), Positives = 181/336 (53%), Gaps = 15/336 (4%)

Query: 21  HSRLIVLHYNHSGR-LAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRR 79
           ++  I   YN+SG+ L+    P+D  + AL GL+V  S LV+L NLLV+AAI S+ R  +
Sbjct: 9   YNETIGFFYNNSGKELSSHWRPKDVVVVAL-GLTV--SVLVLLTNLLVIAAIASNRRFHQ 65

Query: 80  WVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFT 139
            +YY L N+  +DL  G AYL  +  +G RT RL+   WFLR+GLL T+L AS  +LL  
Sbjct: 66  PIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAI 125

Query: 140 AGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPL 199
           A ER  +++     S   +   V   +G+ W+ A  LG+LP   W+CLCA DRCS + PL
Sbjct: 126 AVERHRSVMAVQLHSRLPRGRVVMLIVGV-WVAALGLGLLPAHSWHCLCALDRCSRMAPL 184

Query: 200 YSKRYI----LFCLVIFAGVLATIMGLYGAIFRLVQASGQKAP-RPAARRKARRLLKTVL 254
            S+ Y+    L  L++F  ++A    ++  + R VQ   +     P  R     L+KTV+
Sbjct: 185 LSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVV 244

Query: 255 MILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREV 314
           +IL AF+VCW P   +LL D  G    +   L    + L LA  NS VN  +YS R  E+
Sbjct: 245 IILGAFVVCWTPGQVVLLLDGLGCE--SCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEM 302

Query: 315 CRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGAST 350
            R     LCC CLR   R   + +     A  GAST
Sbjct: 303 RRTFRRLLCCACLRQSTR---ESVHYTSSAQGGAST 335


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  169 bits (428), Expect = 4e-42
 Identities = 104/309 (33%), Positives = 157/309 (50%), Gaps = 11/309 (3%)

Query: 21  HSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRW 80
           ++  I   YN SG+           L  + GL +     ++L NLLV+ AI  + R    
Sbjct: 26  YNESIAFFYNRSGKHLATEWNTVSKL--VMGLGITVCIFIMLANLLVMVAIYVNRRFHFP 83

Query: 81  VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTA 140
           +YY + N+  +D   G AY   +  +G  T RL  + W LR+GL+ T+L AS  +LL  A
Sbjct: 84  IYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIA 143

Query: 141 GERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLY 200
            ER  T+ R    +      RV   I + W +A ++G +P +GWNC+C  + CS++ PLY
Sbjct: 144 IERHITVFRMQLHT-RMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLY 202

Query: 201 SKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARR-----LLKTVLM 255
           S  Y++F  +        ++ LY  IF  V+    +  R ++  +  R     LLKTV++
Sbjct: 203 SDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262

Query: 256 ILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVC 315
           +L AF++CW P   LLL DV         Y +   + L LA  NSA+NPIIYS+R +E+ 
Sbjct: 263 VLGAFIICWTPGLVLLLLDVCCPQCDVLAYEK---FFLLLAEFNSAMNPIIYSYRDKEMS 319

Query: 316 RAVLSFLCC 324
                 LCC
Sbjct: 320 ATFRQILCC 328


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  169 bits (428), Expect = 4e-42
 Identities = 104/309 (33%), Positives = 157/309 (50%), Gaps = 11/309 (3%)

Query: 21  HSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRW 80
           ++  I   YN SG+           L  + GL +     ++L NLLV+ AI  + R    
Sbjct: 26  YNESIAFFYNRSGKHLATEWNTVSKL--VMGLGITVCIFIMLANLLVMVAIYVNRRFHFP 83

Query: 81  VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTA 140
           +YY + N+  +D   G AY   +  +G  T RL  + W LR+GL+ T+L AS  +LL  A
Sbjct: 84  IYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIA 143

Query: 141 GERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLY 200
            ER  T+ R    +      RV   I + W +A ++G +P +GWNC+C  + CS++ PLY
Sbjct: 144 IERHITVFRMQLHT-RMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLY 202

Query: 201 SKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARR-----LLKTVLM 255
           S  Y++F  +        ++ LY  IF  V+    +  R ++  +  R     LLKTV++
Sbjct: 203 SDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262

Query: 256 ILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVC 315
           +L AF++CW P   LLL DV         Y +   + L LA  NSA+NPIIYS+R +E+ 
Sbjct: 263 VLGAFIICWTPGLVLLLLDVCCPQCDVLAYEK---FFLLLAEFNSAMNPIIYSYRDKEMS 319

Query: 316 RAVLSFLCC 324
                 LCC
Sbjct: 320 ATFRQILCC 328


>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
          Length = 353

 Score =  161 bits (407), Expect = 1e-39
 Identities = 97/273 (35%), Positives = 148/273 (54%), Gaps = 9/273 (3%)

Query: 58  CLVVL-ENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPA 116
           CL +   N LV+AA+  + +     YY L N+  +D   G AY+  +  +G  +  L   
Sbjct: 41  CLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVN 100

Query: 117 QWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALL 176
           +WFLR+GLL ++L AS  +LL  A ER  +++R    S  TK  RV   I L W +A  +
Sbjct: 101 RWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTK-KRVTLLILLVWAIAIFM 159

Query: 177 GMLPLLGWNCLCAFDRCSSLLPLYSKRYILFC----LVIFAGVLATIMGLYGAIFRLVQA 232
           G +P LGWNCLC    CSSL P+YS+ Y++F     L+ F  ++   + +Y  + R    
Sbjct: 160 GAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNV 219

Query: 233 -SGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW 291
            S   +   + RR   +L+KTV+ +L AF+VCW P   +LL D         ++++   W
Sbjct: 220 LSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVK--RW 277

Query: 292 ILALAVLNSAVNPIIYSFRSREVCRAVLSFLCC 324
            L LA+LNS VNPIIYS++  ++   +   +CC
Sbjct: 278 FLLLALLNSVVNPIIYSYKDEDMYGTMKKMICC 310


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  119 bits (297), Expect = 6e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 357 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
            C G  +      G  DCL +   A++ AS
Sbjct: 414 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 441


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  119 bits (297), Expect = 6e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 357 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
            C G  +      G  DCL +   A++ AS
Sbjct: 414 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 441


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  119 bits (297), Expect = 6e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 357 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
            C G  +      G  DCL +   A++ AS
Sbjct: 414 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 441


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  119 bits (297), Expect = 6e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 357 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
            C G  +      G  DCL +   A++ AS
Sbjct: 414 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 441


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  119 bits (297), Expect = 6e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176

Query: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236

Query: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296

Query: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356

Query: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 357 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413

Query: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
            C G  +      G  DCL +   A++ AS
Sbjct: 414 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 441


>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score =  119 bits (297), Expect = 6e-27
 Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
           A+  LS+      VLENLLVL  I  H RS R    Y+ + ++ ++DLL    ++ + + 
Sbjct: 85  AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 143

Query: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
                 + +   +  + G +  +  AS  SL  TA +R+ ++ RP+A        +    
Sbjct: 144 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 203

Query: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
             L W +A ++ +LPLLGWNC      CS + P   + Y++F + + + +L  I+  Y  
Sbjct: 204 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 263

Query: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
           I         R++Q   QK+              RP   R   RL KT+++IL+  ++CW
Sbjct: 264 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 323

Query: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
           GPL  +++ DVFG      + ++ +  +   L +LNS VNPIIY+ RS+++  A  S   
Sbjct: 324 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 380

Query: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
            C G  +      G  DCL +   A++ AS
Sbjct: 381 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 408


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score =  108 bits (271), Expect = 6e-24
 Identities = 90/276 (32%), Positives = 136/276 (49%), Gaps = 21/276 (7%)

Query: 59  LVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQW 118
           LV  EN LV+A I      R  ++  + ++ ++DLL G      ++L  A  F +  A+ 
Sbjct: 53  LVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLG----LVLHFAAVFCIGSAEM 108

Query: 119 FL-REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLG 177
            L   G+L  A  AS  SLL    +R+ ++   +     T  +R Y  + L W  A  LG
Sbjct: 109 SLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLG 168

Query: 178 MLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLV-----QA 232
           +LP+L WNCL     C  + PL SK +++   + F  V   ++ LY  I R+V     Q 
Sbjct: 169 LLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQI 227

Query: 233 SGQKAPRPAARRKA-RRLLKTVLMILLAFLVCWGPL-FGLLLADVFGSNLWAQEYLRGMD 290
           + Q+   PA+   A R+ + T+ ++L AF  CW P     LL D     L+   YL    
Sbjct: 228 ALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYT--YL---- 281

Query: 291 WILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGC 326
             L  A  NS +NPIIY+FR+++V + VL  +CC C
Sbjct: 282 -TLLPATYNSMINPIIYAFRNQDV-QKVLWAVCCCC 315


>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
          Length = 360

 Score =  103 bits (258), Expect = 2e-22
 Identities = 83/281 (29%), Positives = 133/281 (47%), Gaps = 23/281 (8%)

Query: 48  ALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSG 107
           A+  L      L  LEN+ VL  I S  + RR   Y  +       L GA +LA+V+ + 
Sbjct: 35  AVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGS-----LAGADFLASVVFAC 89

Query: 108 ART-FRL-----APAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSR 161
           +   F +     + A + L+ G +     AS  SLL TA +R+  +  P +        R
Sbjct: 90  SFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGR 149

Query: 162 VYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMG 221
               +G+ W+L+AL+  LPL+GW C C    CS L PL    Y+L  L+  A + + I+ 
Sbjct: 150 ALVTLGIMWVLSALVSYLPLMGWTC-CP-RPCSELFPLIPNDYLLSWLLFIAFLFSGIIY 207

Query: 222 LYGAIF-----RLVQASG---QKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLA 273
            YG +       +   SG   ++ P  A  R   RL KT+ ++L   L+CW P+  L+  
Sbjct: 208 TYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAH 267

Query: 274 DVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREV 314
            +  +   + +  +   +   L ++NS VNP+IY+ RS E+
Sbjct: 268 SL--ATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEI 306


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 75/289 (25%), Positives = 132/289 (45%), Gaps = 23/289 (7%)

Query: 59  LVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQW 118
           L+  EN +V+  I  +   R  ++  + ++ L+DLL G   + N + +       + A  
Sbjct: 57  LISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFA---YLLQSEATK 113

Query: 119 FLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGM 178
            +  GL+  + +AS  SLL    +R+ ++   +        +  Y  + + W  +  LG+
Sbjct: 114 LVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLWGTSICLGL 173

Query: 179 LPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAP 238
           LP++GWNCL     CS + PL +K       V F  + A ++ LY  I ++V     +  
Sbjct: 174 LPVMGWNCLRDESTCSVVRPL-TKNNAAILSVSFLFMFALMLQLYIQICKIVMRHAHQIA 232

Query: 239 ------RPAARRKARRLLKTVLMILLAFLVCWGPL-FGLLLADVFGSNLWAQEYLRGMDW 291
                   +     R+ + T+ +IL  F  CW P     L+AD    +++          
Sbjct: 233 LQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLIADYTYPSIYTYA------- 285

Query: 292 ILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGM----RGPGD 336
            L  A  NS +NP+IY+FR++E+ +A L  +CCGC+   +    R P D
Sbjct: 286 TLLPATYNSIINPVIYAFRNQEIQKA-LCLICCGCIPSSLAQRARSPSD 333


>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
          Length = 362

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 79/285 (27%), Positives = 128/285 (44%), Gaps = 21/285 (7%)

Query: 52  LSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTF 111
           L   +  ++  EN LV+A I S    R  ++  + ++  +DLL G   + + +       
Sbjct: 78  LLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQ----- 132

Query: 112 RLAPAQW--FLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLC 169
            L P++    L  G L  + AAS  SLL    +R+ ++   +          V+  +   
Sbjct: 133 YLVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAAT 192

Query: 170 WLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRL 229
           W ++  LG+LP+LGWNCL     CS + PL ++ ++      F  V   ++ LY  I ++
Sbjct: 193 WTVSLGLGLLPVLGWNCLAERAACSVVRPL-ARSHVALLSAAFFMVFGIMLHLYVRICQV 251

Query: 230 VQ------ASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQ 283
           V       A  Q    P      R+ + T+ ++L  F   W P     +  V GS+    
Sbjct: 252 VWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLP---FAIYCVVGSHEDPA 308

Query: 284 EYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLR 328
            Y       L  A  NS +NPIIY+FR++E+ RA L  L CGC +
Sbjct: 309 VYTYA---TLLPATYNSMINPIIYAFRNQEIQRA-LWLLLCGCFQ 349


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 79/302 (26%), Positives = 128/302 (42%), Gaps = 59/302 (19%)

Query: 52  LSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTF 111
           + +A + L +L N+LV  A+  +   +    Y +V++  +D+  G           A  F
Sbjct: 12  VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVL---------AIPF 62

Query: 112 RLAPAQWFLR--EGLLFTAL------AASTFSLLFTAGERFATMVRPVAESGATKTSRVY 163
            +  +  F     G LF A        +S FSLL  A +R+  +  P+  +G    +R  
Sbjct: 63  AITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAK 122

Query: 164 GFIGLCWLLAALLGMLPLLGWN-------------------CLCAFDRCSSLLPLYSKRY 204
           G I +CW+L+  +G+ P+LGWN                     C F+    ++P+    Y
Sbjct: 123 GIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFE---DVVPMNYMVY 179

Query: 205 ILFCLVIFAGVLATIMGLYGAIF-----RLVQASGQKAPRPAAR---RKARRLLKTVLMI 256
             F   +   +L  ++G+Y  IF     +L Q   Q  P   AR   +K     K++ +I
Sbjct: 180 FNFFACVLVPLL-LMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAII 238

Query: 257 LLAFLVCWGPL-----FGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRS 311
           +  F +CW PL     F     D   + LW       M   + L+  NS VNP IY++R 
Sbjct: 239 VGLFALCWLPLHIINCFTFFCPDCSHAPLWL------MYLAIVLSHTNSVVNPFIYAYRI 292

Query: 312 RE 313
           RE
Sbjct: 293 RE 294


>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 71/289 (24%), Positives = 128/289 (44%), Gaps = 32/289 (11%)

Query: 61  VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTG-AAYLANVLLSGARTFRLAPAQWF 119
           +LEN+LV+ AI  +      +Y+ + ++ ++D+L   ++    + +       L  A  F
Sbjct: 51  LLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAF 110

Query: 120 LR------EGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLA 173
           +R      + ++  ++ AS  SLL  A +R+ T+   +         R    I   W   
Sbjct: 111 VRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFC 170

Query: 174 ALLGMLPLLGWNCLCAFDRCSSLLPLYSKR-YILFCLV-IFAGVLATIMGLYGAIFRLVQ 231
                              C  +  LYS+  Y++ CL+ +F  +L  ++ LY  +F L +
Sbjct: 171 T-----------------GCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLAR 213

Query: 232 ASGQK-APRPAA----RRKARRLLKTVLMILLAFLVCWGPLF-GLLLADVFGSNLWAQEY 285
              ++ A  P A    +R + +   TV M+L  F VCW P F  L L      NL+   +
Sbjct: 214 THVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRF 273

Query: 286 LRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGP 334
           +   +  L L + NS ++P+IY+FRS+E+ +     +CC   R+    P
Sbjct: 274 MSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFP 322


>gi|71999131 opsin 3 [Homo sapiens]
          Length = 402

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 90/340 (26%), Positives = 130/340 (38%), Gaps = 45/340 (13%)

Query: 18  AGGHSRLIVLHYNHSGRLAGRGGPEDGGL---------GALRGLSVAASCLVVL---ENL 65
           +GGH       Y   G  AG  GP   G          G    L++    + +L    NL
Sbjct: 7   SGGHG------YWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL 60

Query: 66  LVLAAITSHMRSRRWVYYCLVNITLSDLLT---GAAYLANVLLSGARTFRLAPAQWFLRE 122
           LVL       R R   +  LVNI+LSDLL    G  +     L     +      W    
Sbjct: 61  LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS 120

Query: 123 GLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLL 182
           G LF  ++ +T ++L  A ER+  +V     +     S  +  I   WL +      PLL
Sbjct: 121 GSLFGIVSIATLTVL--AYERYIRVVH----ARVINFSWAWRAITYIWLYSLAWAGAPLL 174

Query: 183 GWNCL--------CAFDRCSSLLPLYSKRYILF----CLVIFAGVLATIMG--LYGAIFR 228
           GWN          C  D  S         ++LF    CLV+  GV+A   G  LY     
Sbjct: 175 GWNRYILDVHGLGCTVDWKSK--DANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML 232

Query: 229 LVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRG 288
                 Q        +  ++L K   +++  FLVCW P   +    V G        +  
Sbjct: 233 RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISI 292

Query: 289 MDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLR 328
           + ++ A +  N+  NP+IY F  R+  R++L  LC   LR
Sbjct: 293 VSYLFAKS--NTVYNPVIYVFMIRKFRRSLLQLLCLRLLR 330


>gi|4506527 rhodopsin [Homo sapiens]
          Length = 348

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 62/282 (21%), Positives = 128/282 (45%), Gaps = 22/282 (7%)

Query: 64  NLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREG 123
           N L L     H + R  + Y L+N+ ++DL        + L +    + +        EG
Sbjct: 55  NFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEG 114

Query: 124 LLFTALAA-STFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLL 182
              T     + +SL+  A ER+  + +P++     +   + G +   W++A      PL 
Sbjct: 115 FFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMG-VAFTWVMALACAAPPLA 173

Query: 183 GWN--------CLCAFDRCSSLLPLYSKRYILFCLVI-FAGVLATIMGLYGA-IFRLVQA 232
           GW+        C C  D  +    + ++ ++++  V+ F   +  I   YG  +F + +A
Sbjct: 174 GWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEA 233

Query: 233 SGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVF---GSNLWAQEYLRGM 289
           + Q+      ++  + + + V+++++AFL+CW P +  +   +F   GSN +   ++   
Sbjct: 234 AAQQQESATTQKAEKEVTRMVIIMVIAFLICWVP-YASVAFYIFTHQGSN-FGPIFMT-- 289

Query: 290 DWILALAVLNSAV-NPIIYSFRSREVCRAVLSFLCCGCLRLG 330
             I A    ++A+ NP+IY   +++    +L+ +CCG   LG
Sbjct: 290 --IPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLG 329


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)

Query: 59  LVVLENLLVLAAITSHMRSRRW-VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQ 117
           + +L NLLV+ A+    + R+    Y +V++  +DLL       +VL+       L    
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV------SVLVMPFGAIELVQDI 85

Query: 118 WF-------LREGLLFTALAASTFSLLFTAGERF-ATMVRPVAESGATKTSRVYGFIGLC 169
           W        +R  L      AS F L   + +R+ A   +P+         R+   +G C
Sbjct: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145

Query: 170 WLLAALLGMLPLL-GWNCLCAFD-----------RCSSLLPLYSKRYILFCLVI--FAGV 215
           W++   +  LP++ GWN +   D             +  + + +K Y + C V+  +   
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205

Query: 216 LATIMGLYGA------------IFRLVQASGQKAPRPAARRKARRL------LKTVLMIL 257
           L  ++  Y              + +   AS +  P+ A +    R+       KT+ +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 258 LAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW--ILALAVLNSAVNPIIYSFRSREVC 315
             F +CW P F   + D F         + G  W   L L  +NS +NP +Y+F ++   
Sbjct: 266 GCFCLCWAPFFVTNIVDPF-----IDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFR 320

Query: 316 RAVLSFLCC 324
           RA L  LCC
Sbjct: 321 RAFLIILCC 329


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)

Query: 59  LVVLENLLVLAAITSHMRSRRW-VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQ 117
           + +L NLLV+ A+    + R+    Y +V++  +DLL       +VL+       L    
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV------SVLVMPFGAIELVQDI 85

Query: 118 WF-------LREGLLFTALAASTFSLLFTAGERF-ATMVRPVAESGATKTSRVYGFIGLC 169
           W        +R  L      AS F L   + +R+ A   +P+         R+   +G C
Sbjct: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145

Query: 170 WLLAALLGMLPLL-GWNCLCAFD-----------RCSSLLPLYSKRYILFCLVI--FAGV 215
           W++   +  LP++ GWN +   D             +  + + +K Y + C V+  +   
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205

Query: 216 LATIMGLYGA------------IFRLVQASGQKAPRPAARRKARRL------LKTVLMIL 257
           L  ++  Y              + +   AS +  P+ A +    R+       KT+ +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 258 LAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW--ILALAVLNSAVNPIIYSFRSREVC 315
             F +CW P F   + D F         + G  W   L L  +NS +NP +Y+F ++   
Sbjct: 266 GCFCLCWAPFFVTNIVDPF-----IDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFR 320

Query: 316 RAVLSFLCC 324
           RA L  LCC
Sbjct: 321 RAFLIILCC 329


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)

Query: 59  LVVLENLLVLAAITSHMRSRRW-VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQ 117
           + +L NLLV+ A+    + R+    Y +V++  +DLL       +VL+       L    
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV------SVLVMPFGAIELVQDI 85

Query: 118 WF-------LREGLLFTALAASTFSLLFTAGERF-ATMVRPVAESGATKTSRVYGFIGLC 169
           W        +R  L      AS F L   + +R+ A   +P+         R+   +G C
Sbjct: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145

Query: 170 WLLAALLGMLPLL-GWNCLCAFD-----------RCSSLLPLYSKRYILFCLVI--FAGV 215
           W++   +  LP++ GWN +   D             +  + + +K Y + C V+  +   
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205

Query: 216 LATIMGLYGA------------IFRLVQASGQKAPRPAARRKARRL------LKTVLMIL 257
           L  ++  Y              + +   AS +  P+ A +    R+       KT+ +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 258 LAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW--ILALAVLNSAVNPIIYSFRSREVC 315
             F +CW P F   + D F         + G  W   L L  +NS +NP +Y+F ++   
Sbjct: 266 GCFCLCWAPFFVTNIVDPF-----IDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFR 320

Query: 316 RAVLSFLCC 324
           RA L  LCC
Sbjct: 321 RAFLIILCC 329


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)

Query: 59  LVVLENLLVLAAITSHMRSRRW-VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQ 117
           + +L NLLV+ A+    + R+    Y +V++  +DLL       +VL+       L    
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV------SVLVMPFGAIELVQDI 85

Query: 118 WF-------LREGLLFTALAASTFSLLFTAGERF-ATMVRPVAESGATKTSRVYGFIGLC 169
           W        +R  L      AS F L   + +R+ A   +P+         R+   +G C
Sbjct: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145

Query: 170 WLLAALLGMLPLL-GWNCLCAFD-----------RCSSLLPLYSKRYILFCLVI--FAGV 215
           W++   +  LP++ GWN +   D             +  + + +K Y + C V+  +   
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205

Query: 216 LATIMGLYGA------------IFRLVQASGQKAPRPAARRKARRL------LKTVLMIL 257
           L  ++  Y              + +   AS +  P+ A +    R+       KT+ +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 258 LAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW--ILALAVLNSAVNPIIYSFRSREVC 315
             F +CW P F   + D F         + G  W   L L  +NS +NP +Y+F ++   
Sbjct: 266 GCFCLCWAPFFVTNIVDPF-----IDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFR 320

Query: 316 RAVLSFLCC 324
           RA L  LCC
Sbjct: 321 RAFLIILCC 329


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)

Query: 59  LVVLENLLVLAAITSHMRSRRW-VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQ 117
           + +L NLLV+ A+    + R+    Y +V++  +DLL       +VL+       L    
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV------SVLVMPFGAIELVQDI 85

Query: 118 WF-------LREGLLFTALAASTFSLLFTAGERF-ATMVRPVAESGATKTSRVYGFIGLC 169
           W        +R  L      AS F L   + +R+ A   +P+         R+   +G C
Sbjct: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145

Query: 170 WLLAALLGMLPLL-GWNCLCAFD-----------RCSSLLPLYSKRYILFCLVI--FAGV 215
           W++   +  LP++ GWN +   D             +  + + +K Y + C V+  +   
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205

Query: 216 LATIMGLYGA------------IFRLVQASGQKAPRPAARRKARRL------LKTVLMIL 257
           L  ++  Y              + +   AS +  P+ A +    R+       KT+ +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 258 LAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW--ILALAVLNSAVNPIIYSFRSREVC 315
             F +CW P F   + D F         + G  W   L L  +NS +NP +Y+F ++   
Sbjct: 266 GCFCLCWAPFFVTNIVDPF-----IDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFR 320

Query: 316 RAVLSFLCC 324
           RA L  LCC
Sbjct: 321 RAFLIILCC 329


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 54/309 (17%)

Query: 59  LVVLENLLVLAAITSHMRSRRW-VYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQ 117
           + +L NLLV+ A+    + R+    Y +V++  +DLL       +VL+       L    
Sbjct: 32  MAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLV------SVLVMPFGAIELVQDI 85

Query: 118 WF-------LREGLLFTALAASTFSLLFTAGERF-ATMVRPVAESGATKTSRVYGFIGLC 169
           W        +R  L      AS F L   + +R+ A   +P+         R+   +G C
Sbjct: 86  WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145

Query: 170 WLLAALLGMLPLL-GWNCLCAFD-----------RCSSLLPLYSKRYILFCLVI--FAGV 215
           W++   +  LP++ GWN +   D             +  + + +K Y + C V+  +   
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205

Query: 216 LATIMGLYGA------------IFRLVQASGQKAPRPAARRKARRL------LKTVLMIL 257
           L  ++  Y              + +   AS +  P+ A +    R+       KT+ +I+
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIM 265

Query: 258 LAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDW--ILALAVLNSAVNPIIYSFRSREVC 315
             F +CW P F   + D F         + G  W   L L  +NS +NP +Y+F ++   
Sbjct: 266 GCFCLCWAPFFVTNIVDPF-----IDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFR 320

Query: 316 RAVLSFLCC 324
           RA L  LCC
Sbjct: 321 RAFLIILCC 329


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 76/319 (23%), Positives = 136/319 (42%), Gaps = 43/319 (13%)

Query: 27  LHYNHSGRLAGRGGPEDGG----LGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVY 82
           LH N S  L    G  DGG    L     + V    + +LEN+LV+ AI  +      +Y
Sbjct: 23  LHSNASESLGK--GYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMY 80

Query: 83  YCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWF------LREGLLFTALAASTFSL 136
           + + ++ ++D+L   +  +  ++          AQ F      + + ++ ++L AS  SL
Sbjct: 81  FFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSL 140

Query: 137 LFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSL 196
           L  A +R+ T+   +         RV   I   W    + G+L ++              
Sbjct: 141 LSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFII-------------- 186

Query: 197 LPLYS-KRYILFCLV-IFAGVLATIMGLYGAIF--------RLVQASGQKAPRPAARRKA 246
              YS    ++ CL+ +F  +LA +  LY  +F        R+    G  A R  A  K 
Sbjct: 187 ---YSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKG 243

Query: 247 RRLLKTVLMILLAFLVCWGPLFGLLLADVF-GSNLWAQEYLRGMDWILALAVLNSAVNPI 305
                T+ +++  F+VCW P F  L+  +    N +   ++   +  L L + NS ++P+
Sbjct: 244 AI---TLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL 300

Query: 306 IYSFRSREVCRAVLSFLCC 324
           IY+ RS+E+ +     +CC
Sbjct: 301 IYALRSQELRKTFKEIICC 319


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,644,740
Number of Sequences: 37866
Number of extensions: 570877
Number of successful extensions: 3147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 2499
Number of HSP's gapped (non-prelim): 561
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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