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Search of human proteins with 4502995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502995 phakinin [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502995 phakinin [Homo sapiens] 806 0.0
gi|40354195 keratin 18 [Homo sapiens] 192 4e-49
gi|4557888 keratin 18 [Homo sapiens] 192 4e-49
gi|131412228 keratin 13 isoform b [Homo sapiens] 173 2e-43
gi|131412225 keratin 13 isoform a [Homo sapiens] 173 2e-43
gi|27894337 keratin 20 [Homo sapiens] 171 9e-43
gi|24430192 keratin 16 [Homo sapiens] 171 1e-42
gi|24234699 keratin 19 [Homo sapiens] 169 3e-42
gi|4557701 keratin 17 [Homo sapiens] 169 3e-42
gi|15431310 keratin 14 [Homo sapiens] 169 3e-42
gi|24430190 keratin 15 [Homo sapiens] 168 9e-42
gi|4557699 keratin 12 [Homo sapiens] 165 8e-41
gi|195972866 keratin 10 [Homo sapiens] 163 3e-40
gi|4504927 keratin 36 [Homo sapiens] 159 4e-39
gi|116488398 keratin 32 [Homo sapiens] 156 4e-38
gi|192807292 keratin 24 [Homo sapiens] 155 5e-38
gi|94538345 keratin 35 [Homo sapiens] 155 8e-38
gi|10337581 type I hair keratin 3B [Homo sapiens] 151 1e-36
gi|55770882 keratin 37 [Homo sapiens] 149 5e-36
gi|15431318 keratin 38 [Homo sapiens] 147 1e-35
gi|14917117 keratin 33A [Homo sapiens] 146 4e-35
gi|14917119 keratin 34 [Homo sapiens] 146 4e-35
gi|14917115 keratin 31 [Homo sapiens] 145 9e-35
gi|153945736 keratin 27 [Homo sapiens] 144 1e-34
gi|125490370 type I hair keratin KA36 [Homo sapiens] 143 3e-34
gi|114431246 keratin 25D [Homo sapiens] 142 4e-34
gi|31559815 keratin 26 [Homo sapiens] 142 4e-34
gi|31559829 keratin 25 [Homo sapiens] 142 6e-34
gi|55956899 keratin 9 [Homo sapiens] 136 3e-32
gi|4504919 keratin 8 [Homo sapiens] 131 1e-30
>gi|4502995 phakinin [Homo sapiens]
Length = 415
Score = 806 bits (2082), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MSERRVVVDLPTSASSSMPLQRRRASFRGPRSSSSLESPPASRTNAMSGLVRAPGVYVGT 60
MSERRVVVDLPTSASSSMPLQRRRASFRGPRSSSSLESPPASRTNAMSGLVRAPGVYVGT
Sbjct: 1 MSERRVVVDLPTSASSSMPLQRRRASFRGPRSSSSLESPPASRTNAMSGLVRAPGVYVGT 60
Query: 61 APSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMA 120
APSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMA
Sbjct: 61 APSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMA 120
Query: 121 KVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTET 180
KVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTET
Sbjct: 121 KVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTET 180
Query: 181 IQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRN 240
IQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRN
Sbjct: 181 IQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRN 240
Query: 241 YEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQA 300
YEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQA
Sbjct: 241 YEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQA 300
Query: 301 EVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMEL 360
EVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMEL
Sbjct: 301 EVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMEL 360
Query: 361 QNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESG 415
QNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESG
Sbjct: 361 QNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESG 415
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 192 bits (489), Expect = 4e-49
Identities = 130/391 (33%), Positives = 212/391 (54%), Gaps = 24/391 (6%)
Query: 31 RSSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRS 90
RS S+++P S A VY G GG G+R++ + S+ F G+ S
Sbjct: 14 RSLGSVQAPSYGARPVSS----AASVYAGA------GGSGSRIS---VSRSTSFRGGMGS 60
Query: 91 SGLATVPAPGL------ERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKA 144
GLAT A GL + + ++ L L Y+ +V +LE ++ LE+++R HLE K
Sbjct: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
Query: 145 TRSGNWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEE 204
+ +W Q+ ++NAR++LQ + + ADDF+ +YE E R++ E
Sbjct: 121 PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
Query: 205 EINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELE-QMDAP 263
+I+ L KVID+ N+T++ LE++IE+LKEEL + +N+EE+VK L Q+A L ++DAP
Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
Query: 264 IGTGLDDILETIRIQWERDVEKNRVEAGAL-LQAKQQAEVAHMSQTQEEKLAAALRVELH 322
L I+ IR Q++ KNR E Q +++ +Q+ E A EL
Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
Query: 323 NTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAE 382
T VQSL+ + +S+R LK LEN+L + + + ++++ L ++ LE+EL + RAE +
Sbjct: 301 RT---VQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQ 357
Query: 383 QQQQERAHLLARKCQLQKDVASYHALLDREE 413
+Q QE LL K +L+ ++A+Y LL+ E
Sbjct: 358 RQAQEYEALLNIKVKLEAEIATYRRLLEDGE 388
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 192 bits (489), Expect = 4e-49
Identities = 130/391 (33%), Positives = 212/391 (54%), Gaps = 24/391 (6%)
Query: 31 RSSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRS 90
RS S+++P S A VY G GG G+R++ + S+ F G+ S
Sbjct: 14 RSLGSVQAPSYGARPVSS----AASVYAGA------GGSGSRIS---VSRSTSFRGGMGS 60
Query: 91 SGLATVPAPGL------ERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKA 144
GLAT A GL + + ++ L L Y+ +V +LE ++ LE+++R HLE K
Sbjct: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
Query: 145 TRSGNWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEE 204
+ +W Q+ ++NAR++LQ + + ADDF+ +YE E R++ E
Sbjct: 121 PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
Query: 205 EINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELE-QMDAP 263
+I+ L KVID+ N+T++ LE++IE+LKEEL + +N+EE+VK L Q+A L ++DAP
Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
Query: 264 IGTGLDDILETIRIQWERDVEKNRVEAGAL-LQAKQQAEVAHMSQTQEEKLAAALRVELH 322
L I+ IR Q++ KNR E Q +++ +Q+ E A EL
Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
Query: 323 NTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAE 382
T VQSL+ + +S+R LK LEN+L + + + ++++ L ++ LE+EL + RAE +
Sbjct: 301 RT---VQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQ 357
Query: 383 QQQQERAHLLARKCQLQKDVASYHALLDREE 413
+Q QE LL K +L+ ++A+Y LL+ E
Sbjct: 358 RQAQEYEALLNIKVKLEAEIATYRRLLEDGE 388
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 173 bits (439), Expect = 2e-43
Identities = 120/363 (33%), Positives = 199/363 (54%), Gaps = 14/363 (3%)
Query: 55 GVYVGTAPSGCIGGLGARVTRRALGISSVFLQ-GLRSSGLATVPAPGLERDHGAVEDLGG 113
G Y G G GGLG G + F+ G GL T G E+ +++L
Sbjct: 63 GGYGGGLGGGYGGGLGGGFGG---GFAGGFVDFGACDGGLLT----GNEKI--TMQNLND 113
Query: 114 CLVEYMAKVHALEQVSQELETQLR-MHL-ESKATRSGNWGALRASWASSCQQVGEAVLEN 171
L Y+ KV ALE+ + +LE ++R HL +S A+ ++ + ++ A +EN
Sbjct: 114 RLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIEN 173
Query: 172 ARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLK 231
R++L+ + + ADDF+ +YENE R++ E +IN L +V+DE L+K DLE QIESL
Sbjct: 174 NRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLN 233
Query: 232 EELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAG 291
EEL + +N+EE++K Q+ G +MDA G L +L +R Q+E E+NR +A
Sbjct: 234 EELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAE 293
Query: 292 ALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHD 351
AK AE+ T + + + E+ +Q L+ E +S ++K GLENT+ +
Sbjct: 294 EWFHAK-SAELNKEVSTNTAMIQTS-KTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351
Query: 352 AKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDR 411
+ + ++LQ + ++ +EA+L E+R+E E Q QE LL K +L++++A+Y +LL+
Sbjct: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411
Query: 412 EES 414
+++
Sbjct: 412 QDA 414
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 173 bits (439), Expect = 2e-43
Identities = 120/363 (33%), Positives = 199/363 (54%), Gaps = 14/363 (3%)
Query: 55 GVYVGTAPSGCIGGLGARVTRRALGISSVFLQ-GLRSSGLATVPAPGLERDHGAVEDLGG 113
G Y G G GGLG G + F+ G GL T G E+ +++L
Sbjct: 63 GGYGGGLGGGYGGGLGGGFGG---GFAGGFVDFGACDGGLLT----GNEKI--TMQNLND 113
Query: 114 CLVEYMAKVHALEQVSQELETQLR-MHL-ESKATRSGNWGALRASWASSCQQVGEAVLEN 171
L Y+ KV ALE+ + +LE ++R HL +S A+ ++ + ++ A +EN
Sbjct: 114 RLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIEN 173
Query: 172 ARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLK 231
R++L+ + + ADDF+ +YENE R++ E +IN L +V+DE L+K DLE QIESL
Sbjct: 174 NRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLN 233
Query: 232 EELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAG 291
EEL + +N+EE++K Q+ G +MDA G L +L +R Q+E E+NR +A
Sbjct: 234 EELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAE 293
Query: 292 ALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHD 351
AK AE+ T + + + E+ +Q L+ E +S ++K GLENT+ +
Sbjct: 294 EWFHAK-SAELNKEVSTNTAMIQTS-KTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351
Query: 352 AKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDR 411
+ + ++LQ + ++ +EA+L E+R+E E Q QE LL K +L++++A+Y +LL+
Sbjct: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411
Query: 412 EES 414
+++
Sbjct: 412 QDA 414
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 171 bits (434), Expect = 9e-43
Identities = 123/382 (32%), Positives = 196/382 (51%), Gaps = 17/382 (4%)
Query: 33 SSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSG 92
SSSL++P S T M L P VY G GG G R++ ++ + L G
Sbjct: 13 SSSLQAPVVS-TVGMQRLGTTPSVYGGA------GGRGIRISNSRHTVN--YGSDLTGGG 63
Query: 93 LATVPAPGLERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSG-NWG 151
V + A+++L L Y+ KV LEQ + +LE Q++ E+ A R+G ++
Sbjct: 64 DLFVG-----NEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYS 118
Query: 152 ALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYK 211
A Q+ +A L+NAR +LQ + + A+DF+ +YE E+ R E ++ L K
Sbjct: 119 AYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNK 178
Query: 212 VIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDI 271
V D+ L K DLE QIE L ++L L + ++E+V LHK L ++DA G L I
Sbjct: 179 VFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVI 238
Query: 272 LETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSL 331
+ +R ++E +KN EA Q ++Q V T + V+L QSL
Sbjct: 239 MNEMRQKYEVMAQKNLQEAKE--QFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSL 296
Query: 332 QAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHL 391
+ E +S ++K LE+TL + K + +L NL +++ LEA+L +IR+ E+Q E L
Sbjct: 297 EIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHIL 356
Query: 392 LARKCQLQKDVASYHALLDREE 413
L K +L++++A+Y LL+ E+
Sbjct: 357 LDIKTRLEQEIATYRRLLEGED 378
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 171 bits (432), Expect = 1e-42
Identities = 117/361 (32%), Positives = 189/361 (52%), Gaps = 19/361 (5%)
Query: 55 GVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGC 114
G Y G +G GGLGA G F G GL G E+ +++L
Sbjct: 84 GGYGGGLGAGFGGGLGA-------GFGGGFAGG---DGLLV----GSEKV--TMQNLNDR 127
Query: 115 LVEYMAKVHALEQVSQELETQLR-MHLESKATRSGNWGALRASWASSCQQVGEAVLENAR 173
L Y+ KV ALE+ + +LE ++R + + + ++ + ++ A +ENA+
Sbjct: 128 LASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIAATIENAQ 187
Query: 174 LMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEE 233
+LQ + + ADDF+ +YE+E R+ E ++N L +V+DE L + DLE QIE LKEE
Sbjct: 188 PILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEE 247
Query: 234 LGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGAL 293
L L +N+EE++ L Q G +MDA G L IL +R Q+E+ EKNR +A
Sbjct: 248 LAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETW 307
Query: 294 LQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAK 353
+K E + +L + R E+ +Q L+ E +S ++K LEN+L + K
Sbjct: 308 FLSK--TEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETK 365
Query: 354 HWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREE 413
+ M+L + ++G +E +L ++R E EQQ QE LL K +L++++A+Y LL+ E+
Sbjct: 366 GRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGED 425
Query: 414 S 414
+
Sbjct: 426 A 426
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 169 bits (429), Expect = 3e-42
Identities = 117/369 (31%), Positives = 205/369 (55%), Gaps = 19/369 (5%)
Query: 52 RAPGVYVGTAPSGCIGGLGARVTR-RALGISSVFLQGLRSSGLATVPAPGL--ERDHGAV 108
RAP ++ G+ GG G V+ R + SS G G+ T + GL + +
Sbjct: 32 RAPSIHGGS------GGRGVSVSSARFVSSSSSGAYGGGYGGVLTA-SDGLLAGNEKLTM 84
Query: 109 EDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATR-SGNWGALRASWASSCQQVGEA 167
++L L Y+ KV ALE + ELE ++R + + S ++ + ++ A
Sbjct: 85 QNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGA 144
Query: 168 VLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQI 227
+EN+R++LQ + + ADDF+ ++E EQ R + E +IN L +V+DE L + DLE QI
Sbjct: 145 TIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQI 204
Query: 228 ESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNR 287
E LKEEL L +N+EE++ L Q+ G ++D+ GT L IL +R Q+E E+NR
Sbjct: 205 EGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNR 264
Query: 288 VEAGALLQAKQQ---AEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRG 344
+A A ++ + EVA T++ +++ + +L T +Q L+ E +S ++K
Sbjct: 265 KDAEAWFTSRTEELNREVA--GHTEQLQMSRSEVTDLRRT---LQGLEIELQSQLSMKAA 319
Query: 345 LENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVAS 404
LE+TL + + +L ++ A++ +EA+L ++RA++E+Q QE L+ K +L++++A+
Sbjct: 320 LEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIAT 379
Query: 405 YHALLDREE 413
Y +LL+ +E
Sbjct: 380 YRSLLEGQE 388
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 169 bits (429), Expect = 3e-42
Identities = 121/397 (30%), Positives = 206/397 (51%), Gaps = 15/397 (3%)
Query: 26 SFRGPRSSSSLESPP-----ASRTNA-MSGLVRAPGVYVGTAPSGCIGGLGARVTRRALG 79
S R SSSS++ +SRT+ +SG G+ G+ G GGLG+ + +
Sbjct: 4 SIRQFTSSSSIKGSSGLGGGSSRTSCRLSG-----GLGAGSCRLGSAGGLGSTLGGSSYS 58
Query: 80 ISSVFLQGLR-SSGLATVPAPGLERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRM 138
F G S V + +++L L Y+ KV ALE+ + ELE ++R
Sbjct: 59 SCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRD 118
Query: 139 HLESKATRSG-NWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQP 197
+ +A ++ + ++ A ++NA ++LQ + + ADDF+ ++E EQ
Sbjct: 119 WYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQA 178
Query: 198 FRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCEL 257
R + E +IN L +V+DE L + DLE QIE+LKEEL L +N+EE++ L Q+ G
Sbjct: 179 LRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEIN 238
Query: 258 EQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAAL 317
+MDA G L IL +R Q+E+ EKNR +A +K E + +L +
Sbjct: 239 VEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSK--TEELNREVATNSELVQSG 296
Query: 318 RVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREI 377
+ E+ +Q+L+ E +S ++K LE L + ++ + ++L + ++G +E +L ++
Sbjct: 297 KSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQL 356
Query: 378 RAEAEQQQQERAHLLARKCQLQKDVASYHALLDREES 414
R E EQQ QE LL K +L++++A+Y LL+ E++
Sbjct: 357 RCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDA 393
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 169 bits (429), Expect = 3e-42
Identities = 101/308 (32%), Positives = 171/308 (55%), Gaps = 3/308 (0%)
Query: 108 VEDLGGCLVEYMAKVHALEQVSQELETQLR-MHLESKATRSGNWGALRASWASSCQQVGE 166
+++L L Y+ KV ALE+ + +LE ++R + + ++ + ++
Sbjct: 119 MQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILT 178
Query: 167 AVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQ 226
A ++NA ++LQ + + ADDF+ +YE E R + E +IN L +V+DE L + DLE Q
Sbjct: 179 ATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQ 238
Query: 227 IESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKN 286
IESLKEEL L +N+EE++ L Q+ G +MDA G L IL +R Q+E+ EKN
Sbjct: 239 IESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKN 298
Query: 287 RVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLE 346
R +A K E + +L + + E+ +Q+L+ E +S ++K LE
Sbjct: 299 RKDAEEWFFTK--TEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLE 356
Query: 347 NTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYH 406
N+L + K + M+L + ++G +E +L ++R E EQQ QE LL K +L++++A+Y
Sbjct: 357 NSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYR 416
Query: 407 ALLDREES 414
LL+ E++
Sbjct: 417 RLLEGEDA 424
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 168 bits (425), Expect = 9e-42
Identities = 114/369 (30%), Positives = 190/369 (51%), Gaps = 15/369 (4%)
Query: 57 YVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAV-------- 108
+V + G GG G RV G SVF G G+ G G +
Sbjct: 51 FVSSGSGGGYGG-GMRVCGFGGGAGSVFGGGF-GGGVGGGFGGGFGGGDGGLLSGNEKIT 108
Query: 109 -EDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSG--NWGALRASWASSCQQVG 165
++L L Y+ KV ALE+ + +LE ++ + + S ++ + ++
Sbjct: 109 MQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIM 168
Query: 166 EAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLES 225
++N+R++L+ + + ADDF+ +YENE R+ E +IN L +V+DE L + DLE
Sbjct: 169 ATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEM 228
Query: 226 QIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEK 285
QIE L EEL L +N+EE++K QLAG +MDA G L +L +R Q+E EK
Sbjct: 229 QIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEK 288
Query: 286 NRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGL 345
NR + A +K E + ++ + E+ + +Q L+ E +S ++K GL
Sbjct: 289 NRRDVEAWFFSK--TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGL 346
Query: 346 ENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASY 405
EN+L + + + +LQ + ++G LEA+L E+R E E Q QE LL K +L++++A+Y
Sbjct: 347 ENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATY 406
Query: 406 HALLDREES 414
+LL+ +++
Sbjct: 407 RSLLEGQDA 415
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 165 bits (417), Expect = 8e-41
Identities = 115/359 (32%), Positives = 194/359 (54%), Gaps = 18/359 (5%)
Query: 64 GCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMAKVH 123
G GGLG G S L G GL + G E++ +++L L Y+ KV
Sbjct: 92 GSFGGLGMGFGGSPGGGSLGILSG-NDGGLLS----GSEKE--TMQNLNDRLASYLDKVR 144
Query: 124 ALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGE-------AVLENARLML 176
ALE+ + ELE ++R E++ T G A ++ ++ + + A + NA+L+L
Sbjct: 145 ALEEANTELENKIREWYETRGT--GTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLL 202
Query: 177 QTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGS 236
Q + + A+DF+ +YENE R+ E +IN L +V+DE LT+ DLE QIESL EEL
Sbjct: 203 QIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAY 262
Query: 237 LSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQA 296
+ +N+E++++ G +MDA G L +L +R Q+E E+NR +A A
Sbjct: 263 MKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWF-I 321
Query: 297 KQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWH 356
++ E+ T E+L ++ + E+ + Q+L+ E +S A+K+ LE++L +A+ +
Sbjct: 322 EKSGELRKEISTNTEQLQSS-KSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDY 380
Query: 357 DMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESG 415
+L + ++ LEA+L ++RA+AE+Q + LL K +L+ ++ +Y LLD E G
Sbjct: 381 CAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQG 439
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 163 bits (412), Expect = 3e-40
Identities = 103/311 (33%), Positives = 169/311 (54%), Gaps = 6/311 (1%)
Query: 108 VEDLGGCLVEYMAKVHALEQVSQELETQLR----MHLESKATRSGNWGALRASWASSCQQ 163
+++L L Y+ KV ALE+ + ELE +++ H S ++ + Q
Sbjct: 150 MQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQ 209
Query: 164 VGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDL 223
+ +NA ++LQ + + ADDF+ +YENE R++ E +IN L +V+DE LTK DL
Sbjct: 210 ILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADL 269
Query: 224 ESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDV 283
E QIESL EEL L +N+EE++K L G +M+A G L +L +R Q+E+
Sbjct: 270 EMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLA 329
Query: 284 EKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKR 343
E+NR +A A K + + E+ ++ + E+ VQ+L+ E +S ALK+
Sbjct: 330 EQNRKDAEAWFNEKSKELTTEIDNNIEQ--ISSYKSEITELRRNVQALEIELQSQLALKQ 387
Query: 344 GLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVA 403
LE +L + + + ++L + A + LE +L++IRAE E Q E LL K +L+ ++
Sbjct: 388 SLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQ 447
Query: 404 SYHALLDREES 414
+Y +LL+ E S
Sbjct: 448 TYRSLLEGEGS 458
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 159 bits (402), Expect = 4e-39
Identities = 118/382 (30%), Positives = 202/382 (52%), Gaps = 11/382 (2%)
Query: 34 SSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSGL 93
SS+ S + R +++G A G Y+ +A SG + GLG+ + L S G SG
Sbjct: 29 SSIRSVGSCRVPSLAG---AAG-YISSARSG-LSGLGSCLPGSYLS-SECHTSGFVGSGG 82
Query: 94 ATVPAPGLERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATR-SGNWGA 152
+ ++ L L Y+ KV LE+ + ELE++++ E + ++ +
Sbjct: 83 WFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQS 142
Query: 153 LRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKV 212
+ Q++ ENARL+LQ + + ADDF+ +YE E R+ E +IN L ++
Sbjct: 143 YFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRI 202
Query: 213 IDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDIL 272
+DE L K DLE+Q+ESLKEEL L +N+EE+V +L QL ++DA L+ IL
Sbjct: 203 LDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKIL 262
Query: 273 ETIRIQWERDVEKNRVEAGALLQAK-QQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSL 331
E +R Q+E VE NR + A + ++ +S +++ + +EL T V +L
Sbjct: 263 EDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRT---VNAL 319
Query: 332 QAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHL 391
+ E ++ +++ LE+TL + + + +L + ++ +EA+L EIR + E+Q QE L
Sbjct: 320 EIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVL 379
Query: 392 LARKCQLQKDVASYHALLDREE 413
L K +L+ ++A+Y LL+ E+
Sbjct: 380 LDVKARLEGEIATYRHLLEGED 401
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 156 bits (394), Expect = 4e-38
Identities = 119/396 (30%), Positives = 208/396 (52%), Gaps = 20/396 (5%)
Query: 34 SSLESPPASRTNAMSGLVRAPGVYVGTA--PSGCIGGLGARVT-RRALGISSVFLQGL-- 88
+SL+S P + SG+ P + +G P C+ + T R A +S +L
Sbjct: 13 ASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPASCLSKTYLSSSCQ 72
Query: 89 RSSGLATVPAPGLERDHGA--------VEDLGGCLVEYMAKVHALEQVSQELETQLRMHL 140
+SG++ PG GA ++ L L Y+ +V LEQ + ELE++++
Sbjct: 73 AASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEAS 132
Query: 141 ESKA-TRSGNWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFR 199
S+ T + ++ + + Q++ ENAR+++ + + ADDF+ +YE E R
Sbjct: 133 HSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMR 192
Query: 200 KAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQ 259
+ E +IN L +++D+ L K DLE+Q+ESLKEEL L +N+EE+V L QL +
Sbjct: 193 QLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIE 252
Query: 260 MDAPIGTGLDDILETIRIQWERDVEKNR--VEAGALLQAKQQAEVAHMSQTQEEKLAAAL 317
+DA L +LE +R Q+E VE NR VE +Q ++ + S Q + + +
Sbjct: 253 VDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDI 312
Query: 318 RVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREI 377
++L T V +L+ E ++ +L+ LENTL +++ + +L + ++ +EA+L EI
Sbjct: 313 -IDLRRT---VNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEI 368
Query: 378 RAEAEQQQQERAHLLARKCQLQKDVASYHALLDREE 413
RA+ E+Q QE LL + +L+ ++ +Y +LL+ E+
Sbjct: 369 RADLERQNQEYQVLLDVRARLEGEINTYRSLLENED 404
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 155 bits (393), Expect = 5e-38
Identities = 103/314 (32%), Positives = 168/314 (53%), Gaps = 8/314 (2%)
Query: 108 VEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALR--ASWASSCQ--- 162
+++L L Y+ KV ALE+ + +LE +++ + SG+ G+ R + + S +
Sbjct: 144 MQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLR 203
Query: 163 -QVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKM 221
Q+ A +ENA ++L + + ADDF+ +YENE R++ E +IN L KV+D+ +T+
Sbjct: 204 NQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRS 263
Query: 222 DLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWER 281
DLE QIES EEL L +N+EE++K + G +M+A GT L +L +R Q+E
Sbjct: 264 DLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEE 323
Query: 282 DVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRAL 341
E+NR EA KQ A + T + A + + E+ +Q+L+ E +S A+
Sbjct: 324 LAEQNRREAEERFN-KQSASLQAQIST-DAGAATSAKNEITELKRTLQALEIELQSQLAM 381
Query: 342 KRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKD 401
K LE TL D + + +L + + LE E+ +I E + Q E LL K +L+ +
Sbjct: 382 KSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVE 441
Query: 402 VASYHALLDREESG 415
+ +Y LLD E G
Sbjct: 442 IETYRRLLDGEGGG 455
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 155 bits (391), Expect = 8e-38
Identities = 122/405 (30%), Positives = 210/405 (51%), Gaps = 31/405 (7%)
Query: 32 SSSSLESPP-----ASRTNAM--SGLVRAPGVY-VGTAPSGCIGGLGARVTRRALGISSV 83
SS SL+SP ++R +AM S + P + V + S C GLG R + ++
Sbjct: 11 SSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPAL 70
Query: 84 FLQGLRSSGLATVPAPG---------LERDHGAVEDLGGCLVEYMAKVHALEQVSQELET 134
L + G AT + G + ++ L L Y+ KV LEQ + LE+
Sbjct: 71 CLP---AGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLES 127
Query: 135 QLRMHLESKATRSGNWGALRASWASSCQQVGEAVL----ENARLMLQTETIQAGADDFKE 190
++R E + S+ + +++ + L ENARL+++ + + ADDF+
Sbjct: 128 RIREWCEQQVPYMC---PDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRT 184
Query: 191 RYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHK 250
+YE E R+ E +IN L +++D+ L K DLE+Q+ESLKEEL L +N+EE+V L
Sbjct: 185 KYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRC 244
Query: 251 QLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAK-QQAEVAHMSQTQ 309
QL ++DA L+ +LE +R Q+E VE NR +A L + ++ +S ++
Sbjct: 245 QLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSE 304
Query: 310 EEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGR 369
+ + A +EL T V +L+ E ++ +++ LE+TL + + + +L + ++
Sbjct: 305 QLQSCQAEIIELRRT---VNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITN 361
Query: 370 LEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREES 414
+EA+L EIRA+ E+Q QE LL + +L+ ++ +Y LL+ E+S
Sbjct: 362 VEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDS 406
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 151 bits (381), Expect = 1e-36
Identities = 101/305 (33%), Positives = 171/305 (56%), Gaps = 13/305 (4%)
Query: 115 LVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVL----E 170
L Y+ KV LE+ + ELE +R E + S+ + +++ + +L E
Sbjct: 67 LASYLEKVRQLERDNAELENLIR---ERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSE 123
Query: 171 NARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESL 230
NARL++Q + + ADDF+ +Y+ EQ R+ E +INSL +++DE L + DLE+Q+ESL
Sbjct: 124 NARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESL 183
Query: 231 KEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEA 290
KEEL SL +N+E++V L QL ++DA L+ +L R Q+E VE NR E
Sbjct: 184 KEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREV 243
Query: 291 GALLQAKQQAEVAHMSQTQEEKLAA--ALRVELHNTSCQVQSLQAETESLRALKRGLENT 348
A Q E+ + E+L + A +EL T V +L+ E ++ L+ LENT
Sbjct: 244 EQWF-ATQTEELNKQVVSSSEQLQSYQAEIIELRRT---VNALEIELQAQHNLRYSLENT 299
Query: 349 LHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHAL 408
L +++ + +L + +++ +E++L EIR++ E+Q QE LL + +L+ ++ +Y +L
Sbjct: 300 LTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSL 359
Query: 409 LDREE 413
L+ E+
Sbjct: 360 LESED 364
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 149 bits (376), Expect = 5e-36
Identities = 101/304 (33%), Positives = 166/304 (54%), Gaps = 11/304 (3%)
Query: 115 LVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVL----E 170
L Y+ KV LEQ + ELET L LE S+ + +++ + +L E
Sbjct: 115 LANYLEKVRQLEQENAELETTL---LERSKCHESTVCPDYQSYFRTIEELQQKILCSKAE 171
Query: 171 NARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESL 230
NARL++Q + + ADDF+ + E+E+ + E + K++D+A L K DLE+Q ESL
Sbjct: 172 NARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESL 231
Query: 231 KEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEA 290
KEE SL N+E++VK+L QL ++D L+ +L +R Q+E VE N +
Sbjct: 232 KEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDV 291
Query: 291 GALLQAKQQA-EVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTL 349
QA+ + + MS ++E + + +EL C V +L+ E ++ LK L+N+L
Sbjct: 292 EQWFQAQSEGISLQAMSCSEELQCCQSEILELR---CTVNALEVERQAQHTLKDCLQNSL 348
Query: 350 HDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALL 409
+A+ + EL + +++ LE +L EIRA+ E+Q QE LL K +L+ ++A+Y LL
Sbjct: 349 CEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLL 408
Query: 410 DREE 413
+ E+
Sbjct: 409 ESED 412
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 147 bits (372), Expect = 1e-35
Identities = 100/304 (32%), Positives = 166/304 (54%), Gaps = 11/304 (3%)
Query: 115 LVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVL----E 170
L Y+ KV LEQ + ELE L LE S+ + +++ + +L E
Sbjct: 115 LANYLEKVRQLEQENAELEATL---LERSKCHESTVCPDYQSYFHTIEELQQKILCSKAE 171
Query: 171 NARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESL 230
NARL++Q + + ADDF+ + E+E+ R+ E + K++D+A L K DLE+Q ESL
Sbjct: 172 NARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESL 231
Query: 231 KEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEA 290
KEE SL N+E++VK+L QL ++D L+ +L +R Q+E +E NR +
Sbjct: 232 KEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDV 291
Query: 291 GALLQAKQQA-EVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTL 349
QA+ + + MS ++E + + +EL C V +L+ E ++ LK L+N+L
Sbjct: 292 EQWFQAQSEGISLQDMSCSEELQCCQSEILELR---CTVNALEVERQAQHTLKDCLQNSL 348
Query: 350 HDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALL 409
+A+ EL + +++ +E +L EIRA+ E+Q QE LL K +L+ ++A+Y LL
Sbjct: 349 CEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLL 408
Query: 410 DREE 413
+ E+
Sbjct: 409 ESED 412
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 146 bits (368), Expect = 4e-35
Identities = 99/305 (32%), Positives = 168/305 (55%), Gaps = 13/305 (4%)
Query: 115 LVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVL----E 170
L Y+ KV LE+ + ELE +R E + A S+ + +++ + +L E
Sbjct: 67 LASYLEKVRQLERDNAELENLIR---ERSQQQEPLVCASYQSYFKTIEELQQKILCSKSE 123
Query: 171 NARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESL 230
NARL++Q + + +DDF+ +YE E R+ E +IN L +++DE L + DLE+Q+ESL
Sbjct: 124 NARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESL 183
Query: 231 KEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEA 290
KEEL L +N+E++V L QL ++DA L+ +L R Q+E VE NR E
Sbjct: 184 KEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREV 243
Query: 291 GALLQAKQQAEVAHMSQTQEEKLAA--ALRVELHNTSCQVQSLQAETESLRALKRGLENT 348
A Q E+ + E+L + A +EL T V +L+ E ++ L+ LENT
Sbjct: 244 EQWF-ATQTEELNKQVVSSSEQLQSYQAEIIELRRT---VNALEIELQAQHNLRDSLENT 299
Query: 349 LHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHAL 408
L +++ + +L + ++ +E++L EIR++ E+Q QE LL + +L+ ++ +Y +L
Sbjct: 300 LTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSL 359
Query: 409 LDREE 413
L+ E+
Sbjct: 360 LESED 364
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 146 bits (368), Expect = 4e-35
Identities = 111/373 (29%), Positives = 185/373 (49%), Gaps = 34/373 (9%)
Query: 63 SGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAP-------------GLERDHGAVE 109
S C+ LG R + + G G +PA G E++ ++
Sbjct: 46 SCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKE--TMQ 103
Query: 110 DLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGE--- 166
L L Y+ KV LE+ + ELE ++ + + L S+ S + + E
Sbjct: 104 FLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEP------LLCPSYQSYFKTIEELQQ 157
Query: 167 ----AVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMD 222
A ENARL++ + + +DDF+ +Y+ EQ R E +INS+ +++DE L K D
Sbjct: 158 KILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSD 217
Query: 223 LESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERD 282
LESQ+ESL+EEL L +N+EE+V L QL ++D L+ +L R Q+E
Sbjct: 218 LESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEAL 277
Query: 283 VEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAA--ALRVELHNTSCQVQSLQAETESLRA 340
VE NR E A Q E+ + E+L + A +EL T V +L+ E ++
Sbjct: 278 VEINRREVEQWF-ATQTEELNKQVVSSSEQLQSCQAEIIELRRT---VNALEIELQAQHN 333
Query: 341 LKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQK 400
L+ LENTL +++ + +L + +++ +E++L EIR + E+Q QE LL + +L+
Sbjct: 334 LRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLEC 393
Query: 401 DVASYHALLDREE 413
++ +Y +LL+ E+
Sbjct: 394 EINTYRSLLESED 406
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 145 bits (365), Expect = 9e-35
Identities = 98/305 (32%), Positives = 167/305 (54%), Gaps = 13/305 (4%)
Query: 115 LVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVL----E 170
L Y+ KV LE+ + ELE +R E + S+ + +++ + +L E
Sbjct: 67 LASYLEKVRQLERDNAELENLIR---ERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSE 123
Query: 171 NARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESL 230
NARL++Q + + ADDF+ +Y+ E R+ E +IN L +++DE L K DLE+Q+ESL
Sbjct: 124 NARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESL 183
Query: 231 KEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNR--V 288
KEEL L N+E++V L QL ++DA L+ +L R Q+E VE NR V
Sbjct: 184 KEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREV 243
Query: 289 EAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENT 348
E Q ++ + S Q + A + +EL T V +L+ E ++ L+ LENT
Sbjct: 244 EQWFTTQTEELNKQVVSSSEQLQSYQAEI-IELRRT---VNALEIELQAQHNLRDSLENT 299
Query: 349 LHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHAL 408
L +++ + +L + +++ +E++L EIR++ E+Q QE LL + +L+ ++ +Y +L
Sbjct: 300 LTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSL 359
Query: 409 LDREE 413
L+ E+
Sbjct: 360 LESED 364
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 144 bits (363), Expect = 1e-34
Identities = 96/313 (30%), Positives = 162/313 (51%), Gaps = 11/313 (3%)
Query: 108 VEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSC------ 161
+++L L Y+ V ALE+ + +LE +++ E G+ L ++
Sbjct: 88 MQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGP--GSCRGLDHDYSRYFPIIDEL 145
Query: 162 -QQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTK 220
Q+ A NA ++LQ + + ADDF+ ++ENE ++ E +IN L +V+DE L +
Sbjct: 146 KNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCR 205
Query: 221 MDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWE 280
DLE Q+E+L EEL L +N+EE++K L G +M+A G L +L +R ++E
Sbjct: 206 TDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYE 265
Query: 281 RDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRA 340
E+NR +A A K + +S + + R EL +Q+L+ E +SL A
Sbjct: 266 ALAEQNRRDAEAWFNEKSASLQQQIS--DDAGATTSARNELIEMKRTLQTLEIELQSLLA 323
Query: 341 LKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQK 400
K LE +L + + + +L + A +G LE +L ++R E E Q+ E LL K L+K
Sbjct: 324 TKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEK 383
Query: 401 DVASYHALLDREE 413
++ +Y L+D E+
Sbjct: 384 EIETYCLLIDGED 396
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 143 bits (360), Expect = 3e-34
Identities = 91/301 (30%), Positives = 159/301 (52%), Gaps = 3/301 (0%)
Query: 115 LVEYMAKVHALEQVSQELETQLRMHLESKATR-SGNWGALRASWASSCQQVGEAVLENAR 173
L Y+ KV +LE+ + ELE++++ E ++ + Q++ EN+R
Sbjct: 100 LASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSR 159
Query: 174 LMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEE 233
L +Q + + DDFK +YE+E R+ E +I+SL+ +++E L K DLE+ +ESLKE+
Sbjct: 160 LAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKED 219
Query: 234 LGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGAL 293
L L +N+EE+V LL +QL ++D L+ +L+ +R Q E + NR EA
Sbjct: 220 LLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEW 279
Query: 294 LQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAK 353
L Q E + Q + ++E+ +L+ E ++ ++L LE T+ + +
Sbjct: 280 LAV--QTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETE 337
Query: 354 HWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREE 413
+ +L + ++ LE +L EIR + E+Q QE LL K +L+ ++ +Y LLD E+
Sbjct: 338 AQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSED 397
Query: 414 S 414
S
Sbjct: 398 S 398
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 142 bits (359), Expect = 4e-34
Identities = 94/311 (30%), Positives = 159/311 (51%), Gaps = 13/311 (4%)
Query: 108 VEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRS-----GNWGALRASWASSCQ 162
+++L L Y+ V ALE+ + ELE +++ E S ++ +
Sbjct: 90 MQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKN 149
Query: 163 QVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMD 222
++ + NA ++LQ + + ADDF+ +YENE + E +IN L +V+DE L + D
Sbjct: 150 KIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTD 209
Query: 223 LESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERD 282
E Q ESL EE+ L +N+EE++K L G +M+A G L +L +R ++E
Sbjct: 210 QELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEAL 269
Query: 283 VEKNRVEAGALLQAKQ---QAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLR 339
E+NR +A A K Q +++H + A R +L +Q+L+ + +SL
Sbjct: 270 AEQNRKDAEAWFNEKSASLQQQISH-----DSGAATFARSQLTEMRRTLQTLEIQLQSLM 324
Query: 340 ALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQ 399
A K LE +L + + + +L + A +G LE +L ++R E E Q+ E HLL K L+
Sbjct: 325 ATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLE 384
Query: 400 KDVASYHALLD 410
K++ +Y L+D
Sbjct: 385 KEIETYCRLID 395
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 142 bits (359), Expect = 4e-34
Identities = 103/352 (29%), Positives = 172/352 (48%), Gaps = 22/352 (6%)
Query: 67 GGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMAKVHALE 126
GGLG+ LG L G + +++L L Y+ VHALE
Sbjct: 61 GGLGSGACAGFLGNEHSLLSG---------------NEKVTMQNLNDRLASYLDHVHALE 105
Query: 127 QVSQELETQLRMHLE-----SKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTETI 181
+ + +LE +++ E S ++ + +Q+ A + NA ++LQ +
Sbjct: 106 EANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNA 165
Query: 182 QAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNY 241
+ ADDF+ +YENE + E + + L +V+DE L DLE Q E+L EEL L +++
Sbjct: 166 RLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSH 225
Query: 242 EEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAE 301
EE++++L G +M+A G L +L +R ++E E+NR +A A +++
Sbjct: 226 EEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWF--NERSA 283
Query: 302 VAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQ 361
+ E A A R EL +Q+L+ E +SL A+K E +L + + + +LQ
Sbjct: 284 TLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQ 343
Query: 362 NLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREE 413
+ +G +E +L++IR E E Q+ E LL K L+K++ Y LLD EE
Sbjct: 344 QIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEE 395
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 142 bits (358), Expect = 6e-34
Identities = 118/403 (29%), Positives = 194/403 (48%), Gaps = 38/403 (9%)
Query: 32 SSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSS 91
SS+S S P T ++ + G GT S I G+G+ G SS F G SS
Sbjct: 6 SSASRRSCPRPTTGSLR--LYGGGTSFGTGNSCGISGIGS-------GFSSAF--GGSSS 54
Query: 92 GLATV---PAPGLE---------RDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMH 139
G T P G + +++L L Y+ VHALE+ + +LE +++
Sbjct: 55 GGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGW 114
Query: 140 LESKATRSGNWGALRASWASSC-------QQVGEAVLENARLMLQTETIQAGADDFKERY 192
E G+ L ++ Q+ + NA +LQ + + ADDF+ +Y
Sbjct: 115 YEKFGP--GSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKY 172
Query: 193 ENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQL 252
ENE ++ E ++N L +V+DE L + DLE Q E+L EE+ L +N++E++++L
Sbjct: 173 ENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAA 232
Query: 253 AGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEK 312
G +M+A G L +L +R ++E E+NR +A A K A + Q E
Sbjct: 233 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKS----ASLQQQISED 288
Query: 313 LAA--ALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRL 370
+ A + R EL +Q+L+ E +SL A K LE +L + + + +L + A +G L
Sbjct: 289 VGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGAL 348
Query: 371 EAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREE 413
E +L ++R E E Q+ E LL K L+K++ +Y L+ ++
Sbjct: 349 EEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDD 391
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 136 bits (343), Expect = 3e-32
Identities = 86/309 (27%), Positives = 166/309 (53%), Gaps = 4/309 (1%)
Query: 104 DHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESK--ATRSGNWGALRASWASSC 161
+ +++L L Y+ KV ALE+ + +LE +++ + K A N+ +
Sbjct: 153 EKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLK 212
Query: 162 QQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKM 221
Q+ + + N + +L + + DDF+ ++E EQ R+ + +IN L +V+D + K
Sbjct: 213 DQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKS 272
Query: 222 DLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWER 281
DLE Q E+L+EEL +L +N++E++ L Q +G +++ G L L +R ++E+
Sbjct: 273 DLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQ 332
Query: 282 DVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRAL 341
+ KNR + + Q ++ H + +++ ++ + E+ VQ L+ E +S +
Sbjct: 333 LIAKNRKDIENQYET-QITQIEHEVSSSGQEVQSSAK-EVTQLRHGVQELEIELQSQLSK 390
Query: 342 KRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKD 401
K LE +L D K+ + +LQ + + LEA++ ++R E E Q QE + LL+ K +L+K+
Sbjct: 391 KAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKE 450
Query: 402 VASYHALLD 410
+ +YH LL+
Sbjct: 451 IETYHNLLE 459
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 131 bits (329), Expect = 1e-30
Identities = 107/399 (26%), Positives = 194/399 (48%), Gaps = 17/399 (4%)
Query: 24 RASFRGPR--SSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGIS 81
+ S GPR SS S S P SR ++ S + G G G G GI+
Sbjct: 11 KVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMG------GIT 64
Query: 82 SVFLQGLRSSGLATVPAPGLE----RDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLR 137
+V + S L P ++ ++ ++ L ++ KV LEQ ++ LET+
Sbjct: 65 AVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWS 124
Query: 138 MHLESKATRSGNWGALRASWASSCQQVGEAV-LENARLMLQTETIQAGADDFKERYENEQ 196
+ + K RS N + S+ ++ ++ E + E +L + +Q +DFK +YE+E
Sbjct: 125 LLQQQKTARS-NMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEI 183
Query: 197 PFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCE 256
R E E + K +DEA + K++LES++E L +E+ L + YEE+++ L Q++
Sbjct: 184 NKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTS 243
Query: 257 LE-QMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAA 315
+ MD +D I+ ++ Q+E ++R EA ++ Q K + E+ ++ + L
Sbjct: 244 VVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYE-ELQSLAGKHGDDLRR 302
Query: 316 ALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELR 375
+ E+ + + LQAE E L+ + LE + DA+ ++ +++ A + LEA L+
Sbjct: 303 T-KTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQ 361
Query: 376 EIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREES 414
+ + +Q +E L+ K L ++A+Y LL+ EES
Sbjct: 362 RAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEES 400
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,141,619
Number of Sequences: 37866
Number of extensions: 614685
Number of successful extensions: 4541
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 439
Number of HSP's that attempted gapping in prelim test: 3109
Number of HSP's gapped (non-prelim): 1348
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.