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Search of human proteins with 4502395
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502395 beclin 1 [Homo sapiens]
(450 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502395 beclin 1 [Homo sapiens] 910 0.0
gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens] 464 e-131
gi|88943925 PREDICTED: Beclin-1-like protein 1 [Homo sapiens] 464 e-131
gi|239753084 PREDICTED: Beclin-1-like protein 1 [Homo sapiens] 463 e-130
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 51 2e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 51 2e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 49 9e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 49 9e-06
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 49 9e-06
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 49 9e-06
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 49 9e-06
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 49 9e-06
gi|148746195 trichohyalin [Homo sapiens] 48 2e-05
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 48 2e-05
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 48 2e-05
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 48 2e-05
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 47 3e-05
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 47 3e-05
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 47 3e-05
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 47 3e-05
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 47 3e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 47 4e-05
gi|214010216 SMC6 protein [Homo sapiens] 47 4e-05
gi|13375848 SMC6 protein [Homo sapiens] 47 4e-05
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 47 4e-05
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 47 5e-05
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 47 5e-05
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 47 5e-05
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 47 5e-05
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 47 5e-05
>gi|4502395 beclin 1 [Homo sapiens]
Length = 450
Score = 910 bits (2353), Expect = 0.0
Identities = 450/450 (100%), Positives = 450/450 (100%)
Query: 1 MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEE 60
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEE
Sbjct: 1 MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEE 60
Query: 61 ETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTG 120
ETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTG
Sbjct: 61 ETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTG 120
Query: 121 DLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQL 180
DLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQL
Sbjct: 121 DLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQL 180
Query: 181 QMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQ 240
QMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQ
Sbjct: 181 QMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQ 240
Query: 241 LELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEW 300
LELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEW
Sbjct: 241 LELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEW 300
Query: 301 NEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFF 360
NEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFF
Sbjct: 301 NEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFF 360
Query: 361 WDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFN 420
WDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFN
Sbjct: 361 WDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFN 420
Query: 421 SEEQWTKALKFMLTNLKWGLAWVSSQFYNK 450
SEEQWTKALKFMLTNLKWGLAWVSSQFYNK
Sbjct: 421 SEEQWTKALKFMLTNLKWGLAWVSSQFYNK 450
>gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
Length = 431
Score = 464 bits (1193), Expect = e-131
Identities = 244/435 (56%), Positives = 300/435 (68%), Gaps = 10/435 (2%)
Query: 14 VSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETP 73
+ F+CQRC Q LKL S + AP T+ QA+PG+T+E + E E
Sbjct: 4 IRFLCQRCHQALKLSGSSESRSLPA-----APAPTSGQAEPGDTREPGVTTREVTDAEE- 57
Query: 74 RQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVD 133
+QDG S R P +S AN FTL+GE G M LS K GD+FDI+SGQ VD
Sbjct: 58 QQDGASSRSPPGDGSVSKGHANIFTLLGEL---GAMHMLSSIQKAAGDIFDIVSGQAVVD 114
Query: 134 HPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILE-QMNEDDSEQLQMELKELALEEE 192
HPLCEECTD+LL+QLD QL +TE + QNY+RCLE E +ED++ L+ EL++L LEE
Sbjct: 115 HPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEA 174
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVEN 252
RL+QELEDV++N A +L+ QAEA LDQ+E Q+ R+YS KRQQLEL D+L +VEN
Sbjct: 175 RLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVEN 234
Query: 253 QMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVL 312
Q++YA+ Q D+LK+ N F ATF IW G G INNFRLGRLP+V V WNEIN AWGQ L
Sbjct: 235 QLQYARVQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAAL 294
Query: 313 LLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAF 372
LL LAN +GL+FQRYRL+P GNHSYL+SLTD ELPL+C GG F +NK+D AMVAF
Sbjct: 295 LLLTLANTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAF 354
Query: 373 LDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFM 432
LDC+QQFKEE EKGE LPY + VE G +ED GG G YSI+T N++E WTKALKFM
Sbjct: 355 LDCMQQFKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFM 414
Query: 433 LTNLKWGLAWVSSQF 447
L N KW L WV+S++
Sbjct: 415 LINFKWSLIWVASRY 429
>gi|88943925 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
Length = 431
Score = 464 bits (1193), Expect = e-131
Identities = 244/435 (56%), Positives = 300/435 (68%), Gaps = 10/435 (2%)
Query: 14 VSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETP 73
+ F+CQRC Q LKL S + AP T+ QA+PG+T+E + E E
Sbjct: 4 IRFLCQRCHQALKLSGSSESRSLPA-----APAPTSGQAEPGDTREPGVTTREVTDAEE- 57
Query: 74 RQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVD 133
+QDG S R P +S AN FTL+GE G M LS K GD+FDI+SGQ VD
Sbjct: 58 QQDGASSRSPPGDGSVSKGHANIFTLLGEL---GAMHMLSSIQKAAGDIFDIVSGQAVVD 114
Query: 134 HPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILE-QMNEDDSEQLQMELKELALEEE 192
HPLCEECTD+LL+QLD QL +TE + QNY+RCLE E +ED++ L+ EL++L LEE
Sbjct: 115 HPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEA 174
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVEN 252
RL+QELEDV++N A +L+ QAEA LDQ+E Q+ R+YS KRQQLEL D+L +VEN
Sbjct: 175 RLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVEN 234
Query: 253 QMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVL 312
Q++YA+ Q D+LK+ N F ATF IW G G INNFRLGRLP+V V WNEIN AWGQ L
Sbjct: 235 QLQYARVQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAAL 294
Query: 313 LLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAF 372
LL LAN +GL+FQRYRL+P GNHSYL+SLTD ELPL+C GG F +NK+D AMVAF
Sbjct: 295 LLLTLANTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAF 354
Query: 373 LDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFM 432
LDC+QQFKEE EKGE LPY + VE G +ED GG G YSI+T N++E WTKALKFM
Sbjct: 355 LDCMQQFKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFM 414
Query: 433 LTNLKWGLAWVSSQF 447
L N KW L WV+S++
Sbjct: 415 LINFKWSLIWVASRY 429
>gi|239753084 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
Length = 431
Score = 463 bits (1192), Expect = e-130
Identities = 244/435 (56%), Positives = 300/435 (68%), Gaps = 10/435 (2%)
Query: 14 VSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETP 73
+ F+CQRC Q LKL S + AP T+ QA+PG+T+E + E E
Sbjct: 4 IRFLCQRCHQALKLSGSSESRSLPA-----APAPTSGQAEPGDTREPGVTTREVTDAEE- 57
Query: 74 RQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVD 133
+QDG S R P +S AN FTL+GE G M LS K GD+FDI+SGQ VD
Sbjct: 58 QQDGASSRSPPGDGSVSKGHANIFTLLGEL---GAMHMLSSIQKXAGDIFDIVSGQAVVD 114
Query: 134 HPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILE-QMNEDDSEQLQMELKELALEEE 192
HPLCEECTD+LL+QLD QL +TE + QNY+RCLE E +ED++ L+ EL++L LEE
Sbjct: 115 HPLCEECTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEA 174
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVEN 252
RL+QELEDV++N A +L+ QAEA LDQ+E Q+ R+YS KRQQLEL D+L +VEN
Sbjct: 175 RLVQELEDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVEN 234
Query: 253 QMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVL 312
Q++YA+ Q D+LK+ N F ATF IW G G INNFRLGRLP+V V WNEIN AWGQ L
Sbjct: 235 QLQYARVQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAAL 294
Query: 313 LLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAF 372
LL LAN +GL+FQRYRL+P GNHSYL+SLTD ELPL+C GG F +NK+D AMVAF
Sbjct: 295 LLLTLANTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAF 354
Query: 373 LDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFM 432
LDC+QQFKEE EKGE LPY + VE G +ED GG G YSI+T N++E WTKALKFM
Sbjct: 355 LDCMQQFKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFM 414
Query: 433 LTNLKWGLAWVSSQF 447
L N KW L WV+S++
Sbjct: 415 LINFKWSLIWVASRY 429
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/258 (21%), Positives = 109/258 (42%), Gaps = 27/258 (10%)
Query: 34 LDRVTIQELTAPLLTTAQAKPGETQEE-------ETNSGEEPFIETPRQD-GVSRRFIPP 85
+DR I+EL +T A+ E E S E P++ G +
Sbjct: 400 MDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS 459
Query: 86 ARMMSTESANSF-------------TLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDV 132
+R++ E N ++ G AS ME ++RL ++ + Q
Sbjct: 460 SRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQ 519
Query: 133 DHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
C+ + L+ + E +N +R ++ILEQ NE ++ + + + E
Sbjct: 520 SLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE 579
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQRE---YSEFKRQQLELDDELKS 249
++D+EK KI+ E++++ ++ +++ E+ Q ++E Y E + EL++EL
Sbjct: 580 ---ARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHH 636
Query: 250 VENQMRYAQTQLDKLKKT 267
+E + Q ++ LK T
Sbjct: 637 LEKENELLQKKITNLKIT 654
Score = 50.1 bits (118), Expect = 4e-06
Identities = 45/192 (23%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 105 DGGTMENLSRRLKVTGDLFDIMSGQTDV----DHPLCEE------------CTDTLLDQL 148
+ +E +R+LK T D F ++ Q + + L EE C + QL
Sbjct: 664 ENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQ------------ 196
+ E+E + K+ LE+L+ + +E+L++ + L +E +RL +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 197 --ELEDVEKNRKIVAENLEKVQAEAERLDQ---EEAQYQREYSEFKRQQLELDDELKSVE 251
EL+D+E + + +NLE+++ ++RL+Q E ++E S+ ++ + +L+ E K +
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 252 NQMRYAQTQLDK 263
Q T L++
Sbjct: 843 QQAEIKDTTLEE 854
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 7/120 (5%)
Query: 149 DTQLNVTENECQN-YKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKI 207
D++ + E++ ++ K+ LEI E+ L+ L+E ++L QEL+ V+KN +
Sbjct: 951 DSRYKLLESKLESTLKKSLEI----KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 1006
Query: 208 V--AENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
+ ++ E++ + + E+ +++RE E R+ L++ D L VE Q + LK
Sbjct: 1007 LKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALK 1066
Score = 34.7 bits (78), Expect = 0.18
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 9/138 (6%)
Query: 139 ECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQEL 198
E ++ + QL+++L E E Q ++ LE L+ ++ L++L E + L QE
Sbjct: 773 ENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK--------RLEQLEKENKSLEQET 824
Query: 199 EDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQ 258
+EK++K + + ++++ +AE D + + +++ L E+ + +
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GIYKESCVRL 883
Query: 259 TQLDKLKKTNVFNATFHI 276
+L+K K V AT I
Sbjct: 884 KELEKENKELVKRATIDI 901
Score = 33.9 bits (76), Expect = 0.31
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 16/125 (12%)
Query: 145 LDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKN 204
+ + ++L+ E E + K+ LE ++ E +E+L+ EL L E E L +++ N
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGER-AEELENELHHLEKENELLQKKIT----N 650
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
KI E +E L+QE ++ +RE + K+ D K++ Q+ + + +L
Sbjct: 651 LKITCEKIEA-------LEQENSELERENRKLKKTL----DSFKNLTFQLESLEKENSQL 699
Query: 265 KKTNV 269
+ N+
Sbjct: 700 DEENL 704
Score = 33.5 bits (75), Expect = 0.40
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 13/98 (13%)
Query: 178 EQLQMELKELALEEERLIQ---ELEDVEKNRKIVAE-------NLEKVQAEAERLDQEEA 227
+ L++E ++L +L++ +LED+EK K+ E N E V AE ++L E
Sbjct: 1189 KNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEND 1248
Query: 228 QYQREYSEFKRQQLELDDE---LKSVENQMRYAQTQLD 262
+ YS+ ++ L + LKS+ N + QT+L+
Sbjct: 1249 RLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLE 1286
Score = 33.5 bits (75), Expect = 0.40
Identities = 26/122 (21%), Positives = 53/122 (43%), Gaps = 10/122 (8%)
Query: 157 NECQNYKRCLEILEQMNEDDSEQLQME----------LKELALEEERLIQELEDVEKNRK 206
N+ K LE LE+M + + E++ +E K+L E +RL + K +
Sbjct: 1203 NQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETE 1262
Query: 207 IVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
++ + + +++ E+ + + E+S+ K Q +LD + NQ L++
Sbjct: 1263 VLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEE 1322
Query: 267 TN 268
N
Sbjct: 1323 EN 1324
Score = 32.7 bits (73), Expect = 0.69
Identities = 29/141 (20%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 126 MSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELK 185
+SG+ + +E T LL D + V N + Q+ + +++ ++ +
Sbjct: 1023 ISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1082
Query: 186 ELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
LAL+ + + + E+N + +N K+Q E L+ + + ++ QQ L++
Sbjct: 1083 ILALQRQTVSLQ----EQNTTLQTQNA-KLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1137
Query: 246 ELKSVENQMRYAQTQLDKLKK 266
E +SV + ++ D L K
Sbjct: 1138 ENESVIKEREDLKSLYDSLIK 1158
Score = 32.0 bits (71), Expect = 1.2
Identities = 22/104 (21%), Positives = 56/104 (53%), Gaps = 17/104 (16%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQR-- 231
+ + EQ+++ELK L E L+ + ++ ++ + L+ ++ +A R+D+ E++ R
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSD----ARSARMYRDELDALREKAVRVDKLESEVSRYK 333
Query: 232 ------EYSEFKRQQLELDDEL-----KSVENQMRYAQTQLDKL 264
E+ + + ++L+ D+++ +E+Q+ + + DKL
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL 377
Score = 32.0 bits (71), Expect = 1.2
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Query: 145 LDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKN 204
L + +T L + Q L + + QL ++ L E E +I+E ED++
Sbjct: 1093 LQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1152
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVE---NQMRYAQTQL 261
+ ++ EK++ ER E ++ K L+ E + +E NQ+ + QL
Sbjct: 1153 YDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQL 1212
Query: 262 DKLKK 266
+ L+K
Sbjct: 1213 EDLEK 1217
Score = 29.6 bits (65), Expect = 5.8
Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 14/112 (12%)
Query: 160 QNYKRCLEILEQMNEDDSE---QLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQ 216
Q+ +R ++ ++ +D++ + Q +EL ++RLI+ VE+N +Q
Sbjct: 1011 QDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIE----VERNN-------ATLQ 1059
Query: 217 AEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
AE + L + Q + + + + Q L L + S++ Q QTQ KL+ N
Sbjct: 1060 AEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVEN 1111
Score = 29.6 bits (65), Expect = 5.8
Identities = 21/97 (21%), Positives = 47/97 (48%), Gaps = 17/97 (17%)
Query: 151 QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAE 210
QL++T + N L L+ E+++ L +++ L L+ NR ++ +
Sbjct: 1298 QLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQ-------------NRTLLEQ 1344
Query: 211 NLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDEL 247
N+E + E+ QY + +E +RQ+ +L++++
Sbjct: 1345 NMES----KDLFHVEQRQYIDKLNELRRQKEKLEEKI 1377
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/258 (21%), Positives = 109/258 (42%), Gaps = 27/258 (10%)
Query: 34 LDRVTIQELTAPLLTTAQAKPGETQEE-------ETNSGEEPFIETPRQD-GVSRRFIPP 85
+DR I+EL +T A+ E E S E P++ G +
Sbjct: 400 MDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS 459
Query: 86 ARMMSTESANSF-------------TLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDV 132
+R++ E N ++ G AS ME ++RL ++ + Q
Sbjct: 460 SRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQ 519
Query: 133 DHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
C+ + L+ + E +N +R ++ILEQ NE ++ + + + E
Sbjct: 520 SLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE 579
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQRE---YSEFKRQQLELDDELKS 249
++D+EK KI+ E++++ ++ +++ E+ Q ++E Y E + EL++EL
Sbjct: 580 ---ARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHH 636
Query: 250 VENQMRYAQTQLDKLKKT 267
+E + Q ++ LK T
Sbjct: 637 LEKENELLQKKITNLKIT 654
Score = 50.1 bits (118), Expect = 4e-06
Identities = 45/192 (23%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 105 DGGTMENLSRRLKVTGDLFDIMSGQTDV----DHPLCEE------------CTDTLLDQL 148
+ +E +R+LK T D F ++ Q + + L EE C + QL
Sbjct: 664 ENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQ------------ 196
+ E+E + K+ LE+L+ + +E+L++ + L +E +RL +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 197 --ELEDVEKNRKIVAENLEKVQAEAERLDQ---EEAQYQREYSEFKRQQLELDDELKSVE 251
EL+D+E + + +NLE+++ ++RL+Q E ++E S+ ++ + +L+ E K +
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 252 NQMRYAQTQLDK 263
Q T L++
Sbjct: 843 QQAEIKDTTLEE 854
Score = 34.7 bits (78), Expect = 0.18
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 9/138 (6%)
Query: 139 ECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQEL 198
E ++ + QL+++L E E Q ++ LE L+ ++ L++L E + L QE
Sbjct: 773 ENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK--------RLEQLEKENKSLEQET 824
Query: 199 EDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQ 258
+EK++K + + ++++ +AE D + + +++ L E+ + +
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GIYKESCVRL 883
Query: 259 TQLDKLKKTNVFNATFHI 276
+L+K K V AT I
Sbjct: 884 KELEKENKELVKRATIDI 901
Score = 33.9 bits (76), Expect = 0.31
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 16/125 (12%)
Query: 145 LDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKN 204
+ + ++L+ E E + K+ LE ++ E +E+L+ EL L E E L +++ N
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGER-AEELENELHHLEKENELLQKKIT----N 650
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
KI E +E L+QE ++ +RE + K+ D K++ Q+ + + +L
Sbjct: 651 LKITCEKIEA-------LEQENSELERENRKLKKTL----DSFKNLTFQLESLEKENSQL 699
Query: 265 KKTNV 269
+ N+
Sbjct: 700 DEENL 704
Score = 33.5 bits (75), Expect = 0.40
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 13/98 (13%)
Query: 178 EQLQMELKELALEEERLIQ---ELEDVEKNRKIVAE-------NLEKVQAEAERLDQEEA 227
+ L++E ++L +L++ +LED+EK K+ E N E V AE ++L E
Sbjct: 1188 KNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEND 1247
Query: 228 QYQREYSEFKRQQLELDDE---LKSVENQMRYAQTQLD 262
+ YS+ ++ L + LKS+ N + QT+L+
Sbjct: 1248 RLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLE 1285
Score = 33.5 bits (75), Expect = 0.40
Identities = 26/122 (21%), Positives = 53/122 (43%), Gaps = 10/122 (8%)
Query: 157 NECQNYKRCLEILEQMNEDDSEQLQME----------LKELALEEERLIQELEDVEKNRK 206
N+ K LE LE+M + + E++ +E K+L E +RL + K +
Sbjct: 1202 NQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETE 1261
Query: 207 IVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
++ + + +++ E+ + + E+S+ K Q +LD + NQ L++
Sbjct: 1262 VLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEE 1321
Query: 267 TN 268
N
Sbjct: 1322 EN 1323
Score = 32.7 bits (73), Expect = 0.69
Identities = 29/141 (20%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 126 MSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELK 185
+SG+ + +E T LL D + V N + Q+ + +++ ++ +
Sbjct: 1022 ISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1081
Query: 186 ELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
LAL+ + + + E+N + +N K+Q E L+ + + ++ QQ L++
Sbjct: 1082 ILALQRQTVSLQ----EQNTTLQTQNA-KLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1136
Query: 246 ELKSVENQMRYAQTQLDKLKK 266
E +SV + ++ D L K
Sbjct: 1137 ENESVIKEREDLKSLYDSLIK 1157
Score = 32.0 bits (71), Expect = 1.2
Identities = 22/104 (21%), Positives = 56/104 (53%), Gaps = 17/104 (16%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQR-- 231
+ + EQ+++ELK L E L+ + ++ ++ + L+ ++ +A R+D+ E++ R
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSD----ARSARMYRDELDALREKAVRVDKLESEVSRYK 333
Query: 232 ------EYSEFKRQQLELDDEL-----KSVENQMRYAQTQLDKL 264
E+ + + ++L+ D+++ +E+Q+ + + DKL
Sbjct: 334 ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL 377
Score = 32.0 bits (71), Expect = 1.2
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Query: 145 LDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKN 204
L + +T L + Q L + + QL ++ L E E +I+E ED++
Sbjct: 1092 LQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1151
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVE---NQMRYAQTQL 261
+ ++ EK++ ER E ++ K L+ E + +E NQ+ + QL
Sbjct: 1152 YDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQL 1211
Query: 262 DKLKK 266
+ L+K
Sbjct: 1212 EDLEK 1216
Score = 30.4 bits (67), Expect = 3.4
Identities = 37/182 (20%), Positives = 72/182 (39%), Gaps = 26/182 (14%)
Query: 106 GGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTEN-------E 158
G E L + T D + ++ + + E + + L+ +L + N E
Sbjct: 936 GLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995
Query: 159 CQNYKRCLEILEQMNEDD------------SEQLQMELKELALEEERLIQELEDVEKNRK 206
+ K+ E L+Q +++ + + E +E E ++ L +VE+N
Sbjct: 996 LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN- 1054
Query: 207 IVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+QAE + L + Q + + + + Q L L + S++ Q QTQ KL+
Sbjct: 1055 ------ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 1108
Query: 267 TN 268
N
Sbjct: 1109 EN 1110
Score = 29.6 bits (65), Expect = 5.8
Identities = 21/97 (21%), Positives = 47/97 (48%), Gaps = 17/97 (17%)
Query: 151 QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAE 210
QL++T + N L L+ E+++ L +++ L L+ NR ++ +
Sbjct: 1297 QLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQ-------------NRTLLEQ 1343
Query: 211 NLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDEL 247
N+E + E+ QY + +E +RQ+ +L++++
Sbjct: 1344 NMES----KDLFHVEQRQYIDKLNELRRQKEKLEEKI 1376
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 48.9 bits (115), Expect = 9e-06
Identities = 28/121 (23%), Positives = 66/121 (54%), Gaps = 1/121 (0%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
D ++ E E + + LE+M +D E+L+ +++ EEE++ ++ E +++ + +
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Query: 209 AENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
E EK + + L QEE +++E + RQ+ ++ ++ + ++ Q Q Q +K+++
Sbjct: 479 QEQEEKTWRQEKLLKQEEKIWEQE-EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
Query: 269 V 269
V
Sbjct: 538 V 538
Score = 40.8 bits (94), Expect = 0.003
Identities = 23/126 (18%), Positives = 68/126 (53%), Gaps = 4/126 (3%)
Query: 142 DTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDV 201
+ ++ + +L E + Q + ++ E+ + E++Q E +E +E+L+++ E +
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ-EQEEKTWRQEKLLKQEEKI 498
Query: 202 EKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLEL---DDELKSVENQMRYAQ 258
+ + + EK+ + E++ ++E + QR+ + + Q++ L +++++ E +++ +
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Query: 259 TQLDKL 264
+L KL
Sbjct: 559 ERLGKL 564
Score = 36.2 bits (82), Expect = 0.062
Identities = 17/107 (15%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ +L + E E + +++ E+ + E+++ + ++ +EE++ ++ E + + + +
Sbjct: 315 EQELKIREQEEKMWRQ-----EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 209 AENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMR 255
EK++ + E++ ++E + R+ + + Q+ + +++ E +MR
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Score = 36.2 bits (82), Expect = 0.062
Identities = 20/87 (22%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 154 VTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLE 213
+ E E + ++ ++M E D E+++ + +E+ +EE++ + E ++ + + E E
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQD-EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQ 240
K+Q E E++ ++E + QR+ + + Q+
Sbjct: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Score = 35.0 bits (79), Expect = 0.14
Identities = 23/122 (18%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Query: 146 DQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLI-QELEDVEKN 204
D+L +L + Q E+ +N+ E++ + +++ +EE++ QEL+ E+
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
K+ + EK+ + E++ ++E + R+ + + Q+ ++ ++ + + Q + Q +K+
Sbjct: 325 EKMWRQE-EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 265 KK 266
++
Sbjct: 384 QE 385
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/129 (18%), Positives = 70/129 (54%), Gaps = 13/129 (10%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ ++ E Q+ + L +E+ +++ E++Q + +++ +EE++ ++ E + K++
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492
Query: 209 AENLEKVQAEAERL--------DQEEAQYQREYSEFKRQQLELDDE---LKSVENQMRYA 257
+ EK+ + E++ +QEE ++E + +RQ+ ++ ++ L E +M+
Sbjct: 493 KQE-EKIWEQEEKMWRQEEKMWEQEEKMQEQE-EKMQRQEEKMREQEVRLWQQEEKMQEQ 550
Query: 258 QTQLDKLKK 266
+ +L +L++
Sbjct: 551 EVRLQELEE 559
Score = 33.5 bits (75), Expect = 0.40
Identities = 30/146 (20%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Query: 133 DHPLCEECTDTLLDQ--------LDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMEL 184
D P E +T+ D+ L +L + E+E + L + + + + QL +
Sbjct: 200 DAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ--LNVKDLKRKLERAQLLLPQ 257
Query: 185 KELALEEERLIQELEDVEKNRKIVAENLE----KVQAEAERLDQEEAQYQREYSEFKRQQ 240
++L +E +RL +EL+ V + E E Q + E++ ++E + Q + + Q+
Sbjct: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
Query: 241 LELDDELKSVENQMRYAQTQLDKLKK 266
L++ ++ + + Q Q +K+++
Sbjct: 318 LKIREQEEKMWRQEEKMHEQEEKIRE 343
Score = 33.5 bits (75), Expect = 0.40
Identities = 21/120 (17%), Positives = 60/120 (50%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
QL + + E Q+ L+ + NE + Q + +++ +EE++ ++ E + +
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL 318
Query: 207 IVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+ E EK+ + E++ ++E + + + + RQ+ ++ ++ + + Q Q +K+++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Score = 32.3 bits (72), Expect = 0.90
Identities = 28/135 (20%), Positives = 62/135 (45%), Gaps = 19/135 (14%)
Query: 151 QLNVTENECQNY------KRCLEILEQMNEDDSEQLQMELK------------ELALEEE 192
Q V ENE N ++ E++ E + + + ELK E E+E
Sbjct: 279 QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE 338
Query: 193 RLIQELED-VEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVE 251
I+E ED + + + + E EK++ + E++ ++E + + + + + Q+ E+ + + +
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398
Query: 252 NQMRYAQTQLDKLKK 266
Q Q ++ + +K
Sbjct: 399 EQEEKRQEKMWRQEK 413
Score = 30.4 bits (67), Expect = 3.4
Identities = 24/119 (20%), Positives = 61/119 (51%), Gaps = 9/119 (7%)
Query: 154 VTENECQNYKRCLEILEQMNE-DDSEQLQMELKELALEEERLIQELEDV-----EKNRKI 207
+ E E + +++ +I EQ + + E+ +E E++ IQE E+ EK R+
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 208 VAENLEKVQAEAERLDQEEAQYQREYSEFKRQQ---LELDDELKSVENQMRYAQTQLDK 263
+ EK+ + +++ +++ + + + E RQ+ EL++ ++ E ++R + ++ +
Sbjct: 401 EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Score = 30.0 bits (66), Expect = 4.5
Identities = 21/112 (18%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKV 215
E C+ + E E+M + + + E K + +E+++ ++ E + + + + E EK+
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEK-IREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 216 QAEAERL-DQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+ E++ +Q+E ++E +++++ + E K E R + ++ +K
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 48.9 bits (115), Expect = 9e-06
Identities = 28/121 (23%), Positives = 66/121 (54%), Gaps = 1/121 (0%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
D ++ E E + + LE+M +D E+L+ +++ EEE++ ++ E +++ + +
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Query: 209 AENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
E EK + + L QEE +++E + RQ+ ++ ++ + ++ Q Q Q +K+++
Sbjct: 479 QEQEEKTWRQEKLLKQEEKIWEQE-EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
Query: 269 V 269
V
Sbjct: 538 V 538
Score = 40.8 bits (94), Expect = 0.003
Identities = 23/126 (18%), Positives = 68/126 (53%), Gaps = 4/126 (3%)
Query: 142 DTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDV 201
+ ++ + +L E + Q + ++ E+ + E++Q E +E +E+L+++ E +
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ-EQEEKTWRQEKLLKQEEKI 498
Query: 202 EKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLEL---DDELKSVENQMRYAQ 258
+ + + EK+ + E++ ++E + QR+ + + Q++ L +++++ E +++ +
Sbjct: 499 WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Query: 259 TQLDKL 264
+L KL
Sbjct: 559 ERLGKL 564
Score = 36.2 bits (82), Expect = 0.062
Identities = 17/107 (15%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ +L + E E + +++ E+ + E+++ + ++ +EE++ ++ E + + + +
Sbjct: 315 EQELKIREQEEKMWRQ-----EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 209 AENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMR 255
EK++ + E++ ++E + R+ + + Q+ + +++ E +MR
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Score = 36.2 bits (82), Expect = 0.062
Identities = 20/87 (22%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 154 VTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLE 213
+ E E + ++ ++M E D E+++ + +E+ +EE++ + E ++ + + E E
Sbjct: 397 IREQEEKRQEKMWRQEKKMREQD-EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQ 240
K+Q E E++ ++E + QR+ + + Q+
Sbjct: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQE 482
Score = 35.0 bits (79), Expect = 0.14
Identities = 23/122 (18%), Positives = 64/122 (52%), Gaps = 2/122 (1%)
Query: 146 DQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLI-QELEDVEKN 204
D+L +L + Q E+ +N+ E++ + +++ +EE++ QEL+ E+
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
K+ + EK+ + E++ ++E + R+ + + Q+ ++ ++ + + Q + Q +K+
Sbjct: 325 EKMWRQE-EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 265 KK 266
++
Sbjct: 384 QE 385
Score = 35.0 bits (79), Expect = 0.14
Identities = 24/129 (18%), Positives = 70/129 (54%), Gaps = 13/129 (10%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ ++ E Q+ + L +E+ +++ E++Q + +++ +EE++ ++ E + K++
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492
Query: 209 AENLEKVQAEAERL--------DQEEAQYQREYSEFKRQQLELDDE---LKSVENQMRYA 257
+ EK+ + E++ +QEE ++E + +RQ+ ++ ++ L E +M+
Sbjct: 493 KQE-EKIWEQEEKMWRQEEKMWEQEEKMQEQE-EKMQRQEEKMREQEVRLWQQEEKMQEQ 550
Query: 258 QTQLDKLKK 266
+ +L +L++
Sbjct: 551 EVRLQELEE 559
Score = 33.5 bits (75), Expect = 0.40
Identities = 21/120 (17%), Positives = 60/120 (50%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
QL + + E Q+ L+ + NE + Q + +++ +EE++ ++ E + +
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL 318
Query: 207 IVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+ E EK+ + E++ ++E + + + + RQ+ ++ ++ + + Q Q +K+++
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Score = 33.1 bits (74), Expect = 0.53
Identities = 25/124 (20%), Positives = 61/124 (49%), Gaps = 6/124 (4%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
+L +L + E+E + L + + + + QL + ++L +E +RL +EL+ V +
Sbjct: 222 ELQEKLRLVESEKSEIQ--LNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279
Query: 207 IVAENLE----KVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLD 262
E E Q + E++ ++E + Q + + Q+L++ ++ + + Q Q +
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 263 KLKK 266
K+++
Sbjct: 340 KIRE 343
Score = 32.3 bits (72), Expect = 0.90
Identities = 28/135 (20%), Positives = 62/135 (45%), Gaps = 19/135 (14%)
Query: 151 QLNVTENECQNY------KRCLEILEQMNEDDSEQLQMELK------------ELALEEE 192
Q V ENE N ++ E++ E + + + ELK E E+E
Sbjct: 279 QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE 338
Query: 193 RLIQELED-VEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVE 251
I+E ED + + + + E EK++ + E++ ++E + + + + + Q+ E+ + + +
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398
Query: 252 NQMRYAQTQLDKLKK 266
Q Q ++ + +K
Sbjct: 399 EQEEKRQEKMWRQEK 413
Score = 30.4 bits (67), Expect = 3.4
Identities = 24/119 (20%), Positives = 61/119 (51%), Gaps = 9/119 (7%)
Query: 154 VTENECQNYKRCLEILEQMNE-DDSEQLQMELKELALEEERLIQELEDV-----EKNRKI 207
+ E E + +++ +I EQ + + E+ +E E++ IQE E+ EK R+
Sbjct: 341 IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Query: 208 VAENLEKVQAEAERLDQEEAQYQREYSEFKRQQ---LELDDELKSVENQMRYAQTQLDK 263
+ EK+ + +++ +++ + + + E RQ+ EL++ ++ E ++R + ++ +
Sbjct: 401 EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Score = 30.0 bits (66), Expect = 4.5
Identities = 21/112 (18%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKV 215
E C+ + E E+M + + + E K + +E+++ ++ E + + + + E EK+
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEK-IREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 216 QAEAERL-DQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+ E++ +Q+E ++E +++++ + E K E R + ++ +K
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 48.9 bits (115), Expect = 9e-06
Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 125 IMSGQTDVDHPLCEECTDTLLDQLDTQLNVTEN---ECQNYKRCLEILEQMNEDDSEQLQ 181
I+S Q + + C+ D ++ EN E QN K+ ILEQ + +Q +
Sbjct: 195 ILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF-ILEQQEREKLQQKE 253
Query: 182 MELKELALEEERLIQEL--------EDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
+++ L +E+ L L E++ K + + E L++ E ++L Q+E Q +R
Sbjct: 254 LQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLV 313
Query: 234 SEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ + + +ELK +E +++ + +L+K
Sbjct: 314 KQLEEEAKSRAEELKLLEEKLKGKEAELEK 343
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 15/135 (11%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
QL+ L +E + K+ LE + E L ++ + L E+E + + +N
Sbjct: 170 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLN 229
Query: 207 IVAENLEKV----QAEAERLDQEE------AQYQREYSEFKRQQL-----ELDDELKSVE 251
+NL++ Q E E+L Q+E Q ++E S Q+L E+ E E
Sbjct: 230 AEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFE 289
Query: 252 NQMRYAQTQLDKLKK 266
+++ +LDKL++
Sbjct: 290 EELKQTLDELDKLQQ 304
Score = 30.0 bits (66), Expect = 4.5
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 178 EQLQMELKEL------ALEEERLIQELEDVEKNR----KIVAENLEKVQAEAERLDQEEA 227
E+L+ L EL + ERL+++LE+ K+R K++ E L+ +AE E+
Sbjct: 290 EELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHT 349
Query: 228 Q----YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
Q Q +Y + L+D E+ ++++ LK N
Sbjct: 350 QATLLLQEKYDSMVQ---SLEDVTAQFESYKALTASEIEDLKLEN 391
Score = 29.6 bits (65), Expect = 5.8
Identities = 24/122 (19%), Positives = 67/122 (54%), Gaps = 21/122 (17%)
Query: 157 NECQNYKRCLEILEQMN--EDDSEQLQMELKELALEEERLIQELEDV-------EKNRKI 207
+E ++ LE +E+++ D E+ ++++ +L EE L ++ +++ E+N I
Sbjct: 139 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQL---EENLKEKNDEILSLKQSLEENIVI 195
Query: 208 VAENLEKVQAEAERLDQEEAQY---QREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
+++ +E + + + L++E+ + RE++E L+ E+++++ + Q + +KL
Sbjct: 196 LSKQVEDLNVKCQLLEKEKEDHVNRNREHNE------NLNAEMQNLKQKFILEQQEREKL 249
Query: 265 KK 266
++
Sbjct: 250 QQ 251
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 48.9 bits (115), Expect = 9e-06
Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 125 IMSGQTDVDHPLCEECTDTLLDQLDTQLNVTEN---ECQNYKRCLEILEQMNEDDSEQLQ 181
I+S Q + + C+ D ++ EN E QN K+ ILEQ + +Q +
Sbjct: 282 ILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF-ILEQQEREKLQQKE 340
Query: 182 MELKELALEEERLIQEL--------EDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
+++ L +E+ L L E++ K + + E L++ E ++L Q+E Q +R
Sbjct: 341 LQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLV 400
Query: 234 SEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ + + +ELK +E +++ + +L+K
Sbjct: 401 KQLEEEAKSRAEELKLLEEKLKGKEAELEK 430
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 15/135 (11%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
QL+ L +E + K+ LE + E L ++ + L E+E + + +N
Sbjct: 257 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLN 316
Query: 207 IVAENLEKV----QAEAERLDQEE------AQYQREYSEFKRQQL-----ELDDELKSVE 251
+NL++ Q E E+L Q+E Q ++E S Q+L E+ E E
Sbjct: 317 AEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFE 376
Query: 252 NQMRYAQTQLDKLKK 266
+++ +LDKL++
Sbjct: 377 EELKQTLDELDKLQQ 391
Score = 30.0 bits (66), Expect = 4.5
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 178 EQLQMELKEL------ALEEERLIQELEDVEKNR----KIVAENLEKVQAEAERLDQEEA 227
E+L+ L EL + ERL+++LE+ K+R K++ E L+ +AE E+
Sbjct: 377 EELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHT 436
Query: 228 Q----YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
Q Q +Y + L+D E+ ++++ LK N
Sbjct: 437 QATLLLQEKYDSMVQ---SLEDVTAQFESYKALTASEIEDLKLEN 478
Score = 29.6 bits (65), Expect = 5.8
Identities = 24/122 (19%), Positives = 67/122 (54%), Gaps = 21/122 (17%)
Query: 157 NECQNYKRCLEILEQMN--EDDSEQLQMELKELALEEERLIQELEDV-------EKNRKI 207
+E ++ LE +E+++ D E+ ++++ +L EE L ++ +++ E+N I
Sbjct: 226 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQL---EENLKEKNDEILSLKQSLEENIVI 282
Query: 208 VAENLEKVQAEAERLDQEEAQY---QREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
+++ +E + + + L++E+ + RE++E L+ E+++++ + Q + +KL
Sbjct: 283 LSKQVEDLNVKCQLLEKEKEDHVNRNREHNE------NLNAEMQNLKQKFILEQQEREKL 336
Query: 265 KK 266
++
Sbjct: 337 QQ 338
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 48.9 bits (115), Expect = 9e-06
Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 125 IMSGQTDVDHPLCEECTDTLLDQLDTQLNVTEN---ECQNYKRCLEILEQMNEDDSEQLQ 181
I+S Q + + C+ D ++ EN E QN K+ ILEQ + +Q +
Sbjct: 266 ILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF-ILEQQEREKLQQKE 324
Query: 182 MELKELALEEERLIQEL--------EDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
+++ L +E+ L L E++ K + + E L++ E ++L Q+E Q +R
Sbjct: 325 LQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLV 384
Query: 234 SEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ + + +ELK +E +++ + +L+K
Sbjct: 385 KQLEEEAKSRAEELKLLEEKLKGKEAELEK 414
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 15/135 (11%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
QL+ L +E + K+ LE + E L ++ + L E+E + + +N
Sbjct: 241 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLN 300
Query: 207 IVAENLEKV----QAEAERLDQEE------AQYQREYSEFKRQQL-----ELDDELKSVE 251
+NL++ Q E E+L Q+E Q ++E S Q+L E+ E E
Sbjct: 301 AEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFE 360
Query: 252 NQMRYAQTQLDKLKK 266
+++ +LDKL++
Sbjct: 361 EELKQTLDELDKLQQ 375
Score = 30.0 bits (66), Expect = 4.5
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 178 EQLQMELKEL------ALEEERLIQELEDVEKNR----KIVAENLEKVQAEAERLDQEEA 227
E+L+ L EL + ERL+++LE+ K+R K++ E L+ +AE E+
Sbjct: 361 EELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHT 420
Query: 228 Q----YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
Q Q +Y + L+D E+ ++++ LK N
Sbjct: 421 QATLLLQEKYDSMVQ---SLEDVTAQFESYKALTASEIEDLKLEN 462
Score = 29.6 bits (65), Expect = 5.8
Identities = 24/122 (19%), Positives = 67/122 (54%), Gaps = 21/122 (17%)
Query: 157 NECQNYKRCLEILEQMN--EDDSEQLQMELKELALEEERLIQELEDV-------EKNRKI 207
+E ++ LE +E+++ D E+ ++++ +L EE L ++ +++ E+N I
Sbjct: 210 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQL---EENLKEKNDEILSLKQSLEENIVI 266
Query: 208 VAENLEKVQAEAERLDQEEAQY---QREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
+++ +E + + + L++E+ + RE++E L+ E+++++ + Q + +KL
Sbjct: 267 LSKQVEDLNVKCQLLEKEKEDHVNRNREHNE------NLNAEMQNLKQKFILEQQEREKL 320
Query: 265 KK 266
++
Sbjct: 321 QQ 322
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 48.9 bits (115), Expect = 9e-06
Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 125 IMSGQTDVDHPLCEECTDTLLDQLDTQLNVTEN---ECQNYKRCLEILEQMNEDDSEQLQ 181
I+S Q + + C+ D ++ EN E QN K+ ILEQ + +Q +
Sbjct: 281 ILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF-ILEQQEREKLQQKE 339
Query: 182 MELKELALEEERLIQEL--------EDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
+++ L +E+ L L E++ K + + E L++ E ++L Q+E Q +R
Sbjct: 340 LQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLV 399
Query: 234 SEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ + + +ELK +E +++ + +L+K
Sbjct: 400 KQLEEEAKSRAEELKLLEEKLKGKEAELEK 429
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 15/135 (11%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRK 206
QL+ L +E + K+ LE + E L ++ + L E+E + + +N
Sbjct: 256 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLN 315
Query: 207 IVAENLEKV----QAEAERLDQEE------AQYQREYSEFKRQQL-----ELDDELKSVE 251
+NL++ Q E E+L Q+E Q ++E S Q+L E+ E E
Sbjct: 316 AEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFE 375
Query: 252 NQMRYAQTQLDKLKK 266
+++ +LDKL++
Sbjct: 376 EELKQTLDELDKLQQ 390
Score = 30.0 bits (66), Expect = 4.5
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 17/105 (16%)
Query: 178 EQLQMELKEL------ALEEERLIQELEDVEKNR----KIVAENLEKVQAEAERLDQEEA 227
E+L+ L EL + ERL+++LE+ K+R K++ E L+ +AE E+
Sbjct: 376 EELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHT 435
Query: 228 Q----YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTN 268
Q Q +Y + L+D E+ ++++ LK N
Sbjct: 436 QATLLLQEKYDSMVQ---SLEDVTAQFESYKALTASEIEDLKLEN 477
Score = 29.6 bits (65), Expect = 5.8
Identities = 24/122 (19%), Positives = 67/122 (54%), Gaps = 21/122 (17%)
Query: 157 NECQNYKRCLEILEQMN--EDDSEQLQMELKELALEEERLIQELEDV-------EKNRKI 207
+E ++ LE +E+++ D E+ ++++ +L EE L ++ +++ E+N I
Sbjct: 225 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQL---EENLKEKNDEILSLKQSLEENIVI 281
Query: 208 VAENLEKVQAEAERLDQEEAQY---QREYSEFKRQQLELDDELKSVENQMRYAQTQLDKL 264
+++ +E + + + L++E+ + RE++E L+ E+++++ + Q + +KL
Sbjct: 282 LSKQVEDLNVKCQLLEKEKEDHVNRNREHNE------NLNAEMQNLKQKFILEQQEREKL 335
Query: 265 KK 266
++
Sbjct: 336 QQ 337
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/163 (28%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 99 LIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENE 158
L+GE + + L R+ + +L Q + + L EE + + Q E
Sbjct: 1063 LLGEERETRRRQELERQYRKEEEL------QQEEEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 159 CQNYKRCL-EILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQA 217
Q ++ L E E+ + E+ E +E+ EEE+L++E + EK R+ + LE+
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE--EPEKRRR---QELERQYR 1171
Query: 218 EAERLDQEEAQYQREYSEFKRQQLEL----DDELKSVENQMRY 256
E E L QEE Q RE E +RQ+ E ++EL+ + + RY
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/123 (27%), Positives = 64/123 (52%), Gaps = 6/123 (4%)
Query: 142 DTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDV 201
+T+L + + +L E E Q + E EQ+ + + ++L+ E +E +++RL +E +
Sbjct: 250 ETVLRKEEEKLQ--EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 202 EKNRKIVAENLEKVQAEAERLDQE----EAQYQREYSEFKRQQLELDDELKSVENQMRYA 257
K + E E+ + + ER +Q+ E Q +RE E + QQL + E + E Q+R
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 258 QTQ 260
Q +
Sbjct: 368 QEE 370
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 138 EECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQE 197
EE D L + +T+ + E Q KR +Q E L++E +E ++ER Q+
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKR-----DQEEERRERWLKLEEEERREQQERREQQ 506
Query: 198 LEDVEKNRKIVAENLEKVQAEAERLDQE---EAQYQREYSEFKRQQLELDDELKSVENQM 254
L ++ R+ E K Q E ERL Q E Q +RE E +R+QL +E K +E +
Sbjct: 507 LRREQEERR---EQRLKRQEEEERLQQRLRSEQQLRREQEE-RREQLLKREEEKRLEQER 562
Query: 255 R 255
R
Sbjct: 563 R 563
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/192 (26%), Positives = 83/192 (43%), Gaps = 28/192 (14%)
Query: 58 QEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLK 117
QEEE GEE ET R+ + R++ + E L+ E + + R+ +
Sbjct: 1058 QEEEQLLGEER--ETRRRQELERQYRKEEELQQEEEQ----LLREEPEKRRRQERERQCR 1111
Query: 118 VTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDS 177
+L Q + + L EE +L+ Q E Q ++ L E+
Sbjct: 1112 EEEEL------QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR------EEPE 1159
Query: 178 EQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFK 237
++ + EL+ EEE L QE E +++ E EK + E ER +EE + QR+ K
Sbjct: 1160 KRRRQELERQYREEEELQQEEE------QLLREEQEKRRQERERQYREEEELQRQ----K 1209
Query: 238 RQQLELDDELKS 249
R+Q D++ +S
Sbjct: 1210 RKQRYRDEDQRS 1221
Score = 38.5 bits (88), Expect = 0.013
Identities = 39/126 (30%), Positives = 56/126 (44%), Gaps = 28/126 (22%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQEL--------------EDV 201
E Q R + L + E+ EQL +E LE+ER Q L E+
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 202 EKNRKIVAENLEKVQ-----AEAERLDQEEAQYQR----EYSEFKRQQLELDDELKSVEN 252
+ +++ E E+++ E ERL+QEE + QR E E +RQQL LKS E
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL-----LKSEEQ 639
Query: 253 QMRYAQ 258
+ R Q
Sbjct: 640 EERRQQ 645
Score = 38.5 bits (88), Expect = 0.013
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 10/102 (9%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQY 229
E+ + E+ + K+L +EE+L+ E + EK R+ + EK E E L QEE Q
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGE--EPEKRRR---QEREKKYREEEELQQEEEQL 1003
Query: 230 QREYSEFKR-----QQLELDDELKSVENQMRYAQTQLDKLKK 266
RE E +R +Q DEL+ E Q+ + + +L++
Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Score = 37.7 bits (86), Expect = 0.021
Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 9/101 (8%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKV--QAEAERLDQE-- 225
+Q+ + E+ + LK EEERL Q L ++ R+ E E++ + E +RL+QE
Sbjct: 505 QQLRREQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 226 EAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
E + +RE E + Q L+ ++E Q R + Q ++L++
Sbjct: 564 EQRLKREQEERRDQLLKREEE----RRQQRLKREQEERLEQ 600
Score = 37.4 bits (85), Expect = 0.028
Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 10/82 (12%)
Query: 178 EQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFK 237
EQL+ E + L EEE L + E+ EK R+ + E+ E E+L QEE Q RE E +
Sbjct: 897 EQLRKEQQLLQEEEEEL--QREEREKRRR---QEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 238 R-----QQLELDDELKSVENQM 254
R +Q D +L+ E Q+
Sbjct: 952 RRQERERQYRKDKKLQQKEEQL 973
Score = 37.0 bits (84), Expect = 0.037
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 13/135 (9%)
Query: 131 DVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALE 190
D D EE + D + E + + +R + LE+ +QL+ E E
Sbjct: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE-----EQQLRQERHRKFRE 1465
Query: 191 EERLIQELEDV-----EKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
EE+L+QE E+ E++RK + E + + E +R +E+ + E +R+ LE +
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ---ELRSQEPERKFLEEEQ 1522
Query: 246 ELKSVENQMRYAQTQ 260
+L + Q ++ Q +
Sbjct: 1523 QLHRQQRQRKFLQEE 1537
Score = 35.4 bits (80), Expect = 0.11
Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELK-ELALEEERLIQELEDVEKNRKIVAENLEK 214
E E + ++ L +Q+ + + + +L+ E L E+ ++ + + + +++ E +
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 215 VQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQ 258
+ E ER +Q+ Q +RE KR+Q E D LK E R+ Q
Sbjct: 427 REQEEERHEQKHEQERRE-QRLKREQEERRDWLKREEETERHEQ 469
Score = 35.0 bits (79), Expect = 0.14
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 10/115 (8%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKE-------LALEEERLIQELEDVEKNRKIV 208
E E + + L E+ +++ Q Q EL+E L +E R ++ E+ ++ R
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 209 AENLEKVQAEAERLDQE---EAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQ 260
+ L + Q E R QE E Q +RE E +R+Q ++ + E Q+R Q +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Score = 35.0 bits (79), Expect = 0.14
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQE---E 226
EQ E +QL+ E +E E++L +E E+ + +++ E E+ + + R +Q+ E
Sbjct: 329 EQQEERREQQLRREQEER--REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 227 AQYQREYSEFKRQQLELDDELKSVENQMRYAQ 258
Q +RE + QQL + +L+ E Q+R Q
Sbjct: 387 QQLRREQQLRREQQLRREQQLRR-EQQLRREQ 417
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/108 (30%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 156 ENECQNYKRCL--EILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLE 213
E E Q + L E E+ + E+ + EL EEE+L++E E+ ++ + E E
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE----EREKRRLQER-E 1047
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQL 261
+ E E L QEE Q E E +R+Q EL+ + + E +++ + QL
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQ-ELERQYRK-EEELQQEEEQL 1093
Score = 35.0 bits (79), Expect = 0.14
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKV 215
ENE ++ ++ ++ D + L E +E E+ER + D + E E+
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 216 QAEA-ERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQ 260
+A+ +R QEE Q RE E KR++ E D + + E ++ + Q
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Score = 34.7 bits (78), Expect = 0.18
Identities = 65/279 (23%), Positives = 101/279 (36%), Gaps = 59/279 (21%)
Query: 17 VCQRCSQPLKLDTSFKILD-----RVTIQELTAPLLTTAQA-------KPGETQEEETN- 63
V +R P +D ++LD RV E + AQA G +E+
Sbjct: 44 VLRRPHDPKTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARC 103
Query: 64 SGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLF 123
G+E ++ RQ+ RRF P R + E RR K
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQR-----------------RRQKRQEQER 146
Query: 124 DIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNE--------- 174
++ G+ + E D + D +L E Q + EQ+
Sbjct: 147 ELAEGEEQSEKQERLEQRDR--QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 175 DDSEQLQ----MELKELALEE---------ERLIQELEDVEKNRKIVAENLEKVQAEAER 221
D EQL+ +EL+ EE +R+ QE E+ E ++ ++ E E+
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV-----LRKEEEK 259
Query: 222 LDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQ 260
L +EE Q QRE E + Q +L+ + E Q Q Q
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Score = 34.7 bits (78), Expect = 0.18
Identities = 33/110 (30%), Positives = 60/110 (54%), Gaps = 12/110 (10%)
Query: 145 LDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKN 204
L Q + QL E E KR L+ E+ ++ E+LQ E ++L L EER + +++E+
Sbjct: 1026 LQQEEEQLLREERE----KRRLQERERQYREE-EELQQEEEQL-LGEERETRRRQELERQ 1079
Query: 205 RKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQM 254
+ E++Q E E+L +EE + +R + + +Q ++EL+ E Q+
Sbjct: 1080 YR----KEEELQQEEEQLLREEPEKRRR--QERERQCREEEELQQEEEQL 1123
Score = 34.3 bits (77), Expect = 0.24
Identities = 45/186 (24%), Positives = 78/186 (41%), Gaps = 25/186 (13%)
Query: 58 QEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLK 117
Q+EE GEEP E R+ +++ + E L+ E + + R+ +
Sbjct: 968 QKEEQLLGEEP--EKRRRQEREKKYREEEELQQEEEQ----LLREEREKRRRQEWERQYR 1021
Query: 118 VTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCL-EILEQMNEDD 176
+L Q + + L EE L + + Q E Q ++ L E E +
Sbjct: 1022 KKDEL------QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 177 SEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEF 236
E+ + +EL EEE+L++E + EK R+ E ER +EE + Q+E +
Sbjct: 1076 LERQYRKEEELQQEEEQLLRE--EPEKRRR----------QERERQCREEEELQQEEEQL 1123
Query: 237 KRQQLE 242
R++ E
Sbjct: 1124 LREERE 1129
Score = 33.5 bits (75), Expect = 0.40
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 13/95 (13%)
Query: 174 EDDSEQLQMELKELALEEERLIQELED-----VEKNRKIV--------AENLEKVQAEAE 220
++ +QL+ E E+E+L+QE E+ E++RK + E ++++ + +
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666
Query: 221 RLDQEEAQYQREYSEFKRQQLELDDELKSVENQMR 255
R +EE Q +E E + ++ E D + + E Q+R
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
Score = 33.5 bits (75), Expect = 0.40
Identities = 28/117 (23%), Positives = 60/117 (51%), Gaps = 13/117 (11%)
Query: 156 ENECQNYKRCLEILEQ----MNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAEN 211
E + +R + LE+ ++ +QL+ + EEE+L+QE E+ + R+ E
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ---ER 1689
Query: 212 LEKVQAEAERLDQEEAQ--YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
K + E ++L ++E + + +E + +RQ+L E K E + +T+ ++L++
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQEL----ERKFREEEQLRQETEQEQLRR 1742
Score = 33.5 bits (75), Expect = 0.40
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
Query: 172 MNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQR 231
+ E + +QL+ + ++ EE Q+L E+ RK + E + + E ER +EE Q ++
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEE--QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 232 EYSEFKRQQLELDDELKSV--ENQMR 255
E +++QL + + + E Q+R
Sbjct: 1734 ---ETEQEQLRRQERYRKILEEEQLR 1756
Score = 33.1 bits (74), Expect = 0.53
Identities = 27/105 (25%), Positives = 52/105 (49%), Gaps = 4/105 (3%)
Query: 158 ECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQA 217
E Q +R ++ + E +QL+ E +E E++L +E E+ + +++ E + +
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEE-ERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 218 EAERLDQ--EEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQ 260
+ R Q E Q +RE + QQL + +L+ E Q+R Q +
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRR-EQQLRREQEE 431
Score = 33.1 bits (74), Expect = 0.53
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
E+ E+ + +L + +EER Q+L ++ R+ E K + E ERL+Q + +RE+
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERR---EQRLKREEEEERLEQ---RLKREH 676
Query: 234 SEFKRQQLELDDELKSVENQMR 255
E +R+Q ++E + +++
Sbjct: 677 EEERREQELAEEEQEQARERIK 698
Score = 33.1 bits (74), Expect = 0.53
Identities = 25/114 (21%), Positives = 53/114 (46%), Gaps = 6/114 (5%)
Query: 160 QNYKRCLEILEQMNEDDSEQLQMELK------ELALEEERLIQELEDVEKNRKIVAENLE 213
+ Y++ LE + E + +QL+ + + E L +ER Q+L E +RK E
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
+ + E ++L ++ + + E + Q E + L+ ++ A+ Q +K+
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857
Score = 32.3 bits (72), Expect = 0.90
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 23/136 (16%)
Query: 138 EECTDTLLDQLDTQLNVTENECQNYKRCLEIL-EQMNEDDSEQLQMELKELALEEERLIQ 196
EE + LL + + + E Q KR E +Q+ + + E+ Q LK +EERL Q
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE--QEERLEQ 600
Query: 197 ELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQR--------EYSEFKRQQLELDDE-- 246
L+ E E LE+ + +RL +EE + +R E E ++QQL + +
Sbjct: 601 RLKREE------VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 247 ----LKSVENQMRYAQ 258
LK E + R Q
Sbjct: 655 REQRLKREEEEERLEQ 670
Score = 32.0 bits (71), Expect = 1.2
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 4/104 (3%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKV 215
E + Q R + L + E++ + Q E +E +E R QE ++ R+ E E+
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQ--QERREQQEERREQQLRREQEERREQQ 350
Query: 216 QAEAERLDQEEAQYQREYSEFKR-QQLELDDELKSVENQMRYAQ 258
+ ++ E Q +RE E +R QQL + +L+ E Q+R Q
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRR-EQQLRREQ 393
Score = 32.0 bits (71), Expect = 1.2
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 1/89 (1%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQY 229
E+ E E+ + + + EE R Q + E+ R+ ++ + ++L +E+ +
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 230 QREYSEFKRQQLELDDELKSVENQMRYAQ 258
+RE + QQL + +L+ E Q+R Q
Sbjct: 372 RREQQLRREQQLRREQQLRR-EQQLRREQ 399
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 169 LEQMNEDDSEQLQMELKELALEEERLIQELE-DVEKNRKIVAENLEKVQAEAERLDQE-- 225
L++ E+ + L+ E + E+ER Q+L+ D E+ R+ E K++ E R QE
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR---ERWLKLEEEERREQQERR 503
Query: 226 EAQYQREYSEFKRQQLELDDELKSV------ENQMRYAQTQ 260
E Q +RE E + Q+L+ +E + + E Q+R Q +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Score = 31.6 bits (70), Expect = 1.5
Identities = 25/98 (25%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDV-----EKNRKIVAENLEKVQAEAERLDQEEAQ 228
E + ++ + E EEE+L+QE E+ E++RK E L + Q + + +EE +
Sbjct: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL-RHQEQGRKFLEEEQR 1382
Query: 229 YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+R+ E +R+ L+ + +L+ E + + Q + K ++
Sbjct: 1383 LRRQ--ERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 8/104 (7%)
Query: 160 QNYKRCLEILEQMNED-DSEQLQME------LKELALEEERLIQELEDVEKNRKIVAENL 212
Q +R EQ+ ++ + EQL+ + L+E L ER Q+L E++RK E
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 213 EKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRY 256
+ + E ++L +E+ + E RQ+ E + +L+ + +Y
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQERE-EQQLRPQQRDGKY 1821
Score = 30.0 bits (66), Expect = 4.5
Identities = 24/104 (23%), Positives = 48/104 (46%)
Query: 146 DQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNR 205
++L+ +L E E + E + E + E+ Q LK EE R Q + ++ R
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 206 KIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKS 249
+ + E+ + +RL +E + +RE + +Q + + +KS
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Score = 29.6 bits (65), Expect = 5.8
Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 1/126 (0%)
Query: 133 DHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
+ L +E + L ++ E E +R + L D + + E +L +E+
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVEN 252
RL QE + + + A EK + E + L QEE Q +R+ E K ++ + + K +
Sbjct: 1836 RLRQERDRQYRAEEQFATQ-EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Query: 253 QMRYAQ 258
+ +
Sbjct: 1895 HRQVGE 1900
Score = 29.3 bits (64), Expect = 7.6
Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELK--ELALEEERLIQELEDVEKNRKIVAENLE 213
+ E + +R E+ E+ E E+++ + + LE E ++ + + RK +
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQLE 242
+ Q E R + E Q+Q E ++QQ E
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEE 761
Score = 29.3 bits (64), Expect = 7.6
Identities = 20/94 (21%), Positives = 47/94 (50%), Gaps = 13/94 (13%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
+++ + + EL+ EEE+L QE E + R+ E K+ L++E+ + +RE
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQ---ERYRKI------LEEEQLRPEREE 1761
Query: 234 SEFKRQQLEL----DDELKSVENQMRYAQTQLDK 263
+ +RQ+ + +++L+ + + + D+
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Score = 28.9 bits (63), Expect = 9.9
Identities = 20/76 (26%), Positives = 36/76 (47%)
Query: 185 KELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELD 244
+E L +ER Q+L E++RK E + + E ER E+ Q R ++ + E D
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 245 DELKSVENQMRYAQTQ 260
+ + E ++ + Q
Sbjct: 1619 RKFREDEQLLQEREEQ 1634
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/122 (27%), Positives = 64/122 (52%), Gaps = 10/122 (8%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERL-IQELE--DVEKNR 205
+ ++ + E + + K E ++ E+ + +L + EL EER + EL+ D+E+
Sbjct: 138 EEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 197
Query: 206 KIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
K V NL+ ++A +E+ ++E +Y+ E L D+LK E + +A+ + KL+
Sbjct: 198 KNVTNNLKSLEAASEKYSEKEDKYEEEIK-------LLSDKLKEAETRAEFAERTVAKLE 250
Query: 266 KT 267
KT
Sbjct: 251 KT 252
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/111 (18%), Positives = 52/111 (46%), Gaps = 3/111 (2%)
Query: 146 DQLDTQLNVTENECQNYKRCLEILEQM---NEDDSEQLQMELKELALEEERLIQELEDVE 202
+Q + E++C+ + L L++ ED+ ++ +LK+ + E ++ D E
Sbjct: 23 EQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAE 82
Query: 203 KNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQ 253
+ + ++ V+ E +R + A ++ E ++ E + +K +EN+
Sbjct: 83 GDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/122 (27%), Positives = 64/122 (52%), Gaps = 10/122 (8%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERL-IQELE--DVEKNR 205
+ ++ + E + + K E ++ E+ + +L + EL EER + EL+ D+E+
Sbjct: 102 EEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
Query: 206 KIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
K V NL+ ++A +E+ ++E +Y+ E L D+LK E + +A+ + KL+
Sbjct: 162 KNVTNNLKSLEAASEKYSEKEDKYEEEIK-------LLSDKLKEAETRAEFAERTVAKLE 214
Query: 266 KT 267
KT
Sbjct: 215 KT 216
Score = 33.5 bits (75), Expect = 0.40
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 3/112 (2%)
Query: 157 NECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEK-NRKI--VAENLE 213
N + KR ++ L+Q ++ ++ Q +EL E ER + DV NR+I V E L+
Sbjct: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
+ Q Q+ + ++ E +R +++ E +M + QL + K
Sbjct: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAK 116
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/136 (25%), Positives = 70/136 (51%), Gaps = 4/136 (2%)
Query: 138 EECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQE 197
+E T T++ QL + +V + E ++ L+ ++ +E + ++L K+ E E I+
Sbjct: 676 DEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRT 735
Query: 198 LEDV---EKNR-KIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQ 253
L+ EKN KI LEK++++ +RL +E Q + E + K + L D+L+ E
Sbjct: 736 LKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKH 795
Query: 254 MRYAQTQLDKLKKTNV 269
+ + L ++++ +
Sbjct: 796 ISIEEEHLRRMEEARL 811
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/151 (25%), Positives = 73/151 (48%), Gaps = 22/151 (14%)
Query: 138 EECTDTLLDQLD---TQLNVTENECQNYKRCLEIL--EQMNEDDSEQLQMELKE-LALEE 191
E +TLL Q++ TQL E + + + + + +Q N D + + + E+
Sbjct: 299 EGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVEREK 358
Query: 192 ERLIQELED--VEKNRKIVAENLEKVQAEAERLDQEEAQYQ-------REYSEFKRQQLE 242
+ L +++ D V+ N +A LE+V+ ER D+E+A RE ++QQL+
Sbjct: 359 QDLEKQMSDLRVQLNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQ 418
Query: 243 LDDELKSVEN-------QMRYAQTQLDKLKK 266
+ D LK ++N + ++A Q+ +L +
Sbjct: 419 MLDRLKEIQNHFDTCEAERKHADLQISELTR 449
Score = 37.7 bits (86), Expect = 0.021
Identities = 40/170 (23%), Positives = 80/170 (47%), Gaps = 18/170 (10%)
Query: 122 LFDIMSGQTDVDHPLCEECTDTL---------LDQLDTQLNVTENECQNYKRCLEILEQM 172
L DI S Q D++ + + DT+ ++ +Q+ V + + + E+ +
Sbjct: 567 LRDIKSHQADLELEV-KNSLDTIHRLESELKKQSKIQSQMKVEKAHLE--EEIAELKKSQ 623
Query: 173 NEDDSEQLQME--LKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEA--- 227
+D ++ L+M+ +K+L+ L +L + E+ +K V ++L + A+A+ D+E A
Sbjct: 624 AQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATII 683
Query: 228 -QYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHI 276
Q + E +R+ +L L+SV+ + +L K K A HI
Sbjct: 684 TQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHI 733
Score = 32.0 bits (71), Expect = 1.2
Identities = 28/143 (19%), Positives = 64/143 (44%), Gaps = 17/143 (11%)
Query: 144 LLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELE---- 199
L+++ QL + + Q L+ E ++ ++ +L++ E+ +L QELE
Sbjct: 237 LVERRQDQLGLMSLQLQE---ALKKQEAKADEHEGAIKNKLRQTETEKNQLEQELELSRR 293
Query: 200 ---DVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDE-------LKS 249
E +R+ + +E+++ + + + + Q + S+ +QQ DE +
Sbjct: 294 LLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRG 353
Query: 250 VENQMRYAQTQLDKLKKTNVFNA 272
VE + + + Q+ L+ F+A
Sbjct: 354 VEREKQDLEKQMSDLRVQLNFSA 376
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 47.4 bits (111), Expect = 3e-05
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 45/168 (26%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
L EE D ++L T +L E +R ++++E + D E+ ME++E+ L+E
Sbjct: 58 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK--MEIQEIQLKEA 115
Query: 193 RLIQELED---------------------------------VEKNRKIVAENLEKVQAEA 219
+ I E D +E+ K V NL+ ++A+A
Sbjct: 116 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 175
Query: 220 ERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
E+ Q+E +Y+ E L D+LK E + +A+ + KL+K+
Sbjct: 176 EKYSQKEDRYEEEIK-------VLSDKLKEAETRAEFAERSVTKLEKS 216
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 47.4 bits (111), Expect = 3e-05
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 45/168 (26%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
L EE D ++L T +L E +R ++++E + D E+ ME++E+ L+E
Sbjct: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK--MEIQEIQLKEA 151
Query: 193 RLIQELED---------------------------------VEKNRKIVAENLEKVQAEA 219
+ I E D +E+ K V NL+ ++A+A
Sbjct: 152 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 211
Query: 220 ERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
E+ Q+E +Y+ E L D+LK E + +A+ + KL+K+
Sbjct: 212 EKYSQKEDRYEEEIK-------VLSDKLKEAETRAEFAERSVTKLEKS 252
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 47.4 bits (111), Expect = 3e-05
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 45/168 (26%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
L EE D ++L T +L E +R ++++E + D E+ ME++E+ L+E
Sbjct: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK--MEIQEIQLKEA 151
Query: 193 RLIQELED---------------------------------VEKNRKIVAENLEKVQAEA 219
+ I E D +E+ K V NL+ ++A+A
Sbjct: 152 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 211
Query: 220 ERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
E+ Q+E +Y+ E L D+LK E + +A+ + KL+K+
Sbjct: 212 EKYSQKEDRYEEEIK-------VLSDKLKEAETRAEFAERSVTKLEKS 252
Score = 28.9 bits (63), Expect = 9.9
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
ED S+QL+ EL L + + EL+ + K E LE + +A + + A R
Sbjct: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR-- 90
Query: 234 SEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
R QL +++EL + ++ A +L++ +K
Sbjct: 91 ----RIQL-VEEELDRAQERLATALQKLEEAEK 118
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 47.4 bits (111), Expect = 3e-05
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 45/168 (26%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
L EE D ++L T +L E +R ++++E + D E+ ME++E+ L+E
Sbjct: 94 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK--MEIQEIQLKEA 151
Query: 193 RLIQELED---------------------------------VEKNRKIVAENLEKVQAEA 219
+ I E D +E+ K V NL+ ++A+A
Sbjct: 152 KHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQA 211
Query: 220 ERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
E+ Q+E +Y+ E L D+LK E + +A+ + KL+K+
Sbjct: 212 EKYSQKEDRYEEEIK-------VLSDKLKEAETRAEFAERSVTKLEKS 252
Score = 28.9 bits (63), Expect = 9.9
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)
Query: 174 EDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREY 233
ED S+QL+ EL L + + EL+ + K E LE + +A + + A R
Sbjct: 33 EDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR-- 90
Query: 234 SEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
R QL +++EL + ++ A +L++ +K
Sbjct: 91 ----RIQL-VEEELDRAQERLATALQKLEEAEK 118
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/131 (23%), Positives = 66/131 (50%), Gaps = 17/131 (12%)
Query: 148 LDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELK------ELALEEERLIQELEDV 201
+ ++ + E E ++ ++ LE+M + E LQ+E+K + + + RL++E E+
Sbjct: 410 MQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEK 469
Query: 202 EKNRKIVAEN----LEKVQAEAERLDQEEAQY-------QREYSEFKRQQLELDDELKSV 250
K + E +E+ Q E E L QE AQ Q++ E ++ + D+++++
Sbjct: 470 LKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAA 529
Query: 251 ENQMRYAQTQL 261
+ ++R A T +
Sbjct: 530 QRKLRQASTNV 540
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 7/96 (7%)
Query: 169 LEQMNEDDSEQLQMELKELALEEERL-IQELEDVEKNRKIVA-ENLEKVQAEAERLDQEE 226
L+Q + EQ E + A EEE L +Q+L++ EK RK+ E L++ Q +AERL QEE
Sbjct: 325 LKQKRREQREQ--RERRRAAKEEELLRLQQLQE-EKERKLQELELLQEAQRQAERLLQEE 381
Query: 227 AQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLD 262
+ +R S+ + Q L+ +L+ E Q +++
Sbjct: 382 EERRR--SQHRELQQALEGQLREAEQARASMQAEME 415
Score = 37.7 bits (86), Expect = 0.021
Identities = 25/127 (19%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 147 QLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELE------- 199
+L L E + + ++ ++ E+++ + + +KEL ++RL + L+
Sbjct: 391 ELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARR 450
Query: 200 DVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQT 259
D E R LE+ + + ++L Q + + +R ++++ EL E+ ++ AQ
Sbjct: 451 DEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQ 510
Query: 260 QLDKLKK 266
QL+++++
Sbjct: 511 QLEEVRQ 517
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/94 (26%), Positives = 59/94 (62%), Gaps = 3/94 (3%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQY 229
EQM E + EQ++ + +++ +EE++ ++ E V+K + + + E+++ + E++ ++E Q
Sbjct: 220 EQMGEQE-EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 230 --QREYSEFKRQQLELDDELKSVENQMRYAQTQL 261
Q+E +E + Q E +++++ E QMR + Q+
Sbjct: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQM 312
Score = 45.8 bits (107), Expect = 8e-05
Identities = 25/96 (26%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEE--A 227
EQM E + EQ+Q + +++ +EE++ ++ E + + + + E E++ + E+ +QEE
Sbjct: 234 EQMGEQE-EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 228 QYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ + + E + Q E +++++ E QMR + Q+ K
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Score = 45.8 bits (107), Expect = 8e-05
Identities = 26/126 (20%), Positives = 74/126 (58%), Gaps = 5/126 (3%)
Query: 146 DQLDTQLNVTENECQNYKRCLEILEQMNE--DDSEQLQMELKELALEEERLIQELEDVEK 203
+Q+ Q TE E Q ++ ++ EQ + + EQ++ + +++ +EE++ ++ E + +
Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335
Query: 204 NRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLEL---DDELKSVENQMRYAQTQ 260
++ + E E++ + E++ ++E Q Q++ + ++Q+ ++ +++++ E QMR + Q
Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395
Query: 261 LDKLKK 266
+ + K+
Sbjct: 396 MGEQKE 401
Score = 42.7 bits (99), Expect = 7e-04
Identities = 22/119 (18%), Positives = 62/119 (52%), Gaps = 2/119 (1%)
Query: 145 LDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKN 204
+ + + Q+ E + Q + + E+ EQ+ + +++ +EE++ ++ E + K
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
Query: 205 RKIVAENLEKVQAEAERL--DQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQL 261
+ + E E+++ + E++ +E+ + + + E + Q E +++++ E QMR + Q+
Sbjct: 261 EEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/97 (23%), Positives = 57/97 (58%), Gaps = 5/97 (5%)
Query: 171 QMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQ 230
QM E + EQ+ + +++ +EE++ ++ E + K + + E E+VQ + E++ ++E Q +
Sbjct: 200 QMGEQE-EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258
Query: 231 REYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
++ + Q E +++++ E QM + Q ++ ++T
Sbjct: 259 KQ----EEQMREQEEQMREQEEQMLKQKEQTEQEEQT 291
Score = 41.2 bits (95), Expect = 0.002
Identities = 21/99 (21%), Positives = 57/99 (57%), Gaps = 11/99 (11%)
Query: 171 QMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQ 230
QM E + ++ +EE++ ++ E ++K + + E E+++ + E++ ++E Q Q
Sbjct: 193 QMGEQEG--------QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 231 REYSEFKRQQLEL---DDELKSVENQMRYAQTQLDKLKK 266
++ + ++Q+ ++ +++++ E QMR + Q+ K K+
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Score = 39.7 bits (91), Expect = 0.006
Identities = 23/118 (19%), Positives = 62/118 (52%), Gaps = 3/118 (2%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ Q+ E + + + + E+ + EQ+ + +++ +EE++ ++ E ++K + V
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQV 368
Query: 209 AENLEKVQAEAERLDQEEAQYQR---EYSEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ E+++ + E++ ++E Q ++ + E K Q E ++++ E QM + Q+ K
Sbjct: 369 RKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRK 426
Score = 38.5 bits (88), Expect = 0.013
Identities = 25/118 (21%), Positives = 64/118 (54%), Gaps = 4/118 (3%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ Q+ E + K E EQ E + EQ++ + +++ +EE++ ++ E + + + +
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQE-EQMREQEEQMREQEEQMREQEEQMREQEEQM 326
Query: 209 AENLEKVQAEAERL-DQEEAQYQRE--YSEFKRQQLELDDELKSVENQMRYAQTQLDK 263
+ E++ + E++ +Q+E +++E E + Q + +++++ E QMR + Q+ K
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
Score = 38.5 bits (88), Expect = 0.013
Identities = 25/116 (21%), Positives = 62/116 (53%), Gaps = 5/116 (4%)
Query: 156 ENECQNYKRCLEILEQMNE--DDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLE 213
E E Q K+ ++ EQ + + EQ+ + +++ +EE++ ++ E V K + + + E
Sbjct: 321 EQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE 380
Query: 214 KVQAEAERLDQEEAQ---YQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+++ + E++ ++E Q + + E K Q E ++++ + QMR + + + K+
Sbjct: 381 QMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 35.8 bits (81), Expect = 0.081
Identities = 24/97 (24%), Positives = 57/97 (58%), Gaps = 6/97 (6%)
Query: 170 EQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQY 229
EQM + + EQ++ + +++ +EE+++++ E E+ + E E+++ + E++ ++E Q
Sbjct: 255 EQMRKQE-EQMREQEEQMREQEEQMLKQKEQTEQEEQ-TGEQEEQMREQEEQMREQEEQ- 311
Query: 230 QREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
RE E R+Q ++++ E QM + Q+ + K+
Sbjct: 312 MREQEEQMREQ---EEQMGKQEEQMWEQKEQMWEQKE 345
Score = 34.3 bits (77), Expect = 0.24
Identities = 23/112 (20%), Positives = 61/112 (54%), Gaps = 4/112 (3%)
Query: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDV--EKNRKIVAENLE 213
E E Q ++ ++L+Q + + E+ E +E E+E ++E E+ E+ ++ + +
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325
Query: 214 KVQAEAERLDQEEAQYQREYSEFKRQQL--ELDDELKSVENQMRYAQTQLDK 263
+ E + +Q+E ++++ +K+++ E +++++ E Q+R + Q+ K
Sbjct: 326 MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Score = 29.6 bits (65), Expect = 5.8
Identities = 13/78 (16%), Positives = 42/78 (53%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIV 208
+ Q+ E + Q + + E+ EQ++ + +++ +EE++ ++ E + + ++ +
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
Query: 209 AENLEKVQAEAERLDQEE 226
E E++ + E++ ++E
Sbjct: 411 REQEEQMGEQKEQMRKQE 428
>gi|214010216 SMC6 protein [Homo sapiens]
Length = 1091
Score = 47.0 bits (110), Expect = 4e-05
Identities = 33/123 (26%), Positives = 66/123 (53%), Gaps = 17/123 (13%)
Query: 144 LLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELE---- 199
L D L +LN+ ++E N KR E+ ++ + L + +EL ++E+ L +++
Sbjct: 793 LADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQ 852
Query: 200 ------DVEKNRKIVAENL----EKVQAE-AERLDQEEAQYQREYSEFKRQQLELDDELK 248
+VEK+ I+ + + +K+QAE A D+EE R+Y E + L+LD +++
Sbjct: 853 ICPERIEVEKSASILDKEINRLRQKIQAEHASHGDREE--IMRQYQEARETYLDLDSKVR 910
Query: 249 SVE 251
+++
Sbjct: 911 TLK 913
Score = 42.7 bits (99), Expect = 7e-04
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 8/159 (5%)
Query: 109 MENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEI 168
+ ++ K D + +S +T+ P EC D + + E E Y R L
Sbjct: 318 LNEAEQKYKDIQDKLEKISEETNARAP---ECMALKADVVAKKRAYNEAEVL-YNRSLNE 373
Query: 169 LEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKI--VAENLEKVQAEAERLDQEE 226
+ + +DD EQL ++EL ++ + E E +E+ +KI + E ++ Q + ++QE
Sbjct: 374 YKALKKDD-EQLCKRIEELKKSTDQSL-EPERLERQKKISWLKERVKAFQNQENSVNQEI 431
Query: 227 AQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
Q+Q+ + K + ++ E V++ + Y Q QL +LK
Sbjct: 432 EQFQQAIEKDKEEHGKIKREELDVKHALSYNQRQLKELK 470
Score = 37.4 bits (85), Expect = 0.028
Identities = 42/205 (20%), Positives = 83/205 (40%), Gaps = 52/205 (25%)
Query: 89 MSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQL 148
+S + + S+ L +++ G + L D F+I VD+P+ L ++
Sbjct: 146 ISIDGSRSYKL--KSATGSVVSTRKEELIAILDHFNIQ-----VDNPV-----SVLTQEM 193
Query: 149 DTQLNVTENECQNYKRCLEI--LEQMNEDDS----------------EQLQMELKELALE 190
Q ++NE YK ++ LEQM ED S E+ ELK +E
Sbjct: 194 SKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQIHQGEERLTELKRQCVE 253
Query: 191 EERLIQEL----------------------EDVEKNRKIVAENLEKVQAEAERLDQEEAQ 228
+E Q + ++EK + +N++ + A RLD++ +
Sbjct: 254 KEERFQSIAGLSTMKTNLESLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEE 313
Query: 229 YQREYSEFKRQQLELDDELKSVENQ 253
Q +E +++ ++ D+L+ + +
Sbjct: 314 QQVRLNEAEQKYKDIQDKLEKISEE 338
Score = 36.2 bits (82), Expect = 0.062
Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 37/153 (24%)
Query: 148 LDTQLNVTENECQNYKRCLEILEQM----------NEDDSEQLQMELKELALEEER---L 194
+D++++ ENE +N + L+Q NE+ ++ Q+ KEL ++ +
Sbjct: 664 VDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRCQLHYKELKMKIRKNISE 723
Query: 195 IQELEDVEKNRKI--------VAENLEKVQAEAERLDQE------------EAQYQREYS 234
I+ELE++E+++ + EN K++ E ++Q+ EA+ + +
Sbjct: 724 IRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAI 783
Query: 235 EFKRQQL-ELDDELKSVENQMRYAQTQLDKLKK 266
+FK QL EL D LK +++ A +++D K+
Sbjct: 784 KFKINQLSELADPLK---DELNLADSEVDNQKR 813
>gi|13375848 SMC6 protein [Homo sapiens]
Length = 1091
Score = 47.0 bits (110), Expect = 4e-05
Identities = 33/123 (26%), Positives = 66/123 (53%), Gaps = 17/123 (13%)
Query: 144 LLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELE---- 199
L D L +LN+ ++E N KR E+ ++ + L + +EL ++E+ L +++
Sbjct: 793 LADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQ 852
Query: 200 ------DVEKNRKIVAENL----EKVQAE-AERLDQEEAQYQREYSEFKRQQLELDDELK 248
+VEK+ I+ + + +K+QAE A D+EE R+Y E + L+LD +++
Sbjct: 853 ICPERIEVEKSASILDKEINRLRQKIQAEHASHGDREE--IMRQYQEARETYLDLDSKVR 910
Query: 249 SVE 251
+++
Sbjct: 911 TLK 913
Score = 42.7 bits (99), Expect = 7e-04
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 8/159 (5%)
Query: 109 MENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEI 168
+ ++ K D + +S +T+ P EC D + + E E Y R L
Sbjct: 318 LNEAEQKYKDIQDKLEKISEETNARAP---ECMALKADVVAKKRAYNEAEVL-YNRSLNE 373
Query: 169 LEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKI--VAENLEKVQAEAERLDQEE 226
+ + +DD EQL ++EL ++ + E E +E+ +KI + E ++ Q + ++QE
Sbjct: 374 YKALKKDD-EQLCKRIEELKKSTDQSL-EPERLERQKKISWLKERVKAFQNQENSVNQEI 431
Query: 227 AQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
Q+Q+ + K + ++ E V++ + Y Q QL +LK
Sbjct: 432 EQFQQAIEKDKEEHGKIKREELDVKHALSYNQRQLKELK 470
Score = 37.4 bits (85), Expect = 0.028
Identities = 42/205 (20%), Positives = 83/205 (40%), Gaps = 52/205 (25%)
Query: 89 MSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQL 148
+S + + S+ L +++ G + L D F+I VD+P+ L ++
Sbjct: 146 ISIDGSRSYKL--KSATGSVVSTRKEELIAILDHFNIQ-----VDNPV-----SVLTQEM 193
Query: 149 DTQLNVTENECQNYKRCLEI--LEQMNEDDS----------------EQLQMELKELALE 190
Q ++NE YK ++ LEQM ED S E+ ELK +E
Sbjct: 194 SKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQIHQGEERLTELKRQCVE 253
Query: 191 EERLIQEL----------------------EDVEKNRKIVAENLEKVQAEAERLDQEEAQ 228
+E Q + ++EK + +N++ + A RLD++ +
Sbjct: 254 KEERFQSIAGLSTMKTNLESLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEE 313
Query: 229 YQREYSEFKRQQLELDDELKSVENQ 253
Q +E +++ ++ D+L+ + +
Sbjct: 314 QQVRLNEAEQKYKDIQDKLEKISEE 338
Score = 36.2 bits (82), Expect = 0.062
Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 37/153 (24%)
Query: 148 LDTQLNVTENECQNYKRCLEILEQM----------NEDDSEQLQMELKELALEEER---L 194
+D++++ ENE +N + L+Q NE+ ++ Q+ KEL ++ +
Sbjct: 664 VDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRCQLHYKELKMKIRKNISE 723
Query: 195 IQELEDVEKNRKI--------VAENLEKVQAEAERLDQE------------EAQYQREYS 234
I+ELE++E+++ + EN K++ E ++Q+ EA+ + +
Sbjct: 724 IRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAI 783
Query: 235 EFKRQQL-ELDDELKSVENQMRYAQTQLDKLKK 266
+FK QL EL D LK +++ A +++D K+
Sbjct: 784 KFKINQLSELADPLK---DELNLADSEVDNQKR 813
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 47.0 bits (110), Expect = 4e-05
Identities = 27/84 (32%), Positives = 45/84 (53%)
Query: 186 ELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
+LA +E L Q+ ED +K ++V +KV E D+EE + E K++Q + ++
Sbjct: 3089 KLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEE 3148
Query: 246 ELKSVENQMRYAQTQLDKLKKTNV 269
+L E + AQ L+ L KTN+
Sbjct: 3149 DLAKAEPALTAAQAALNTLNKTNL 3172
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 46.6 bits (109), Expect = 5e-05
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 12/136 (8%)
Query: 133 DHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEE 192
D P C E D + ++ N E Q LE E+L+ + K + E
Sbjct: 424 DSPSCRET-----DSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLE 478
Query: 193 RLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVEN 252
+ +ELE+ RK V L +++ E L + A+YQR+ D+ +++EN
Sbjct: 479 KTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEA-------DKKRNLEN 531
Query: 253 QMRYAQTQLDKLKKTN 268
+ + QL+ LKK N
Sbjct: 532 DVNSLKDQLEDLKKRN 547
Score = 36.2 bits (82), Expect = 0.062
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 16/170 (9%)
Query: 102 EASDGGTMENLSRRLKVTGDLFDIMS-GQTDVDHPLCEECTDTLLDQLDTQLNVTENEC- 159
EA T L+ + K+ + + S +++ L EE TL +++ L E C
Sbjct: 705 EAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEE--RTLKQKVENLLLEAEKRCS 762
Query: 160 -------QNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENL 212
Q+ ++ E+L+Q + L +++ L L+ E+ Q+ + + K+ + +
Sbjct: 763 LLDCDLKQSQQKINELLKQ-----KDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQV 817
Query: 213 EKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLD 262
++ ++L QE ++Q EL E + + QM+ Q QL+
Sbjct: 818 NTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLE 867
Score = 30.8 bits (68), Expect = 2.6
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 202 EKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQ-------QLELDDELKSVENQM 254
++NRK+ E +++E E+L Q+ +YQ+E +E + Q ++EL L S ++ +
Sbjct: 1061 KENRKLHME----LKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDI 1116
Query: 255 RYAQTQLDKL 264
++QL L
Sbjct: 1117 EQLRSQLQAL 1126
Score = 29.6 bits (65), Expect = 5.8
Identities = 22/94 (23%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 183 ELKELALEEERLIQELE----DVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKR 238
ELKE E+ +L +EL+ +++ R +A LE +A+ + + +YS+ ++
Sbjct: 882 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK 941
Query: 239 QQLELDDELKSVENQMRYAQTQLD----KLKKTN 268
+++ + E+K + + + T+ D L++TN
Sbjct: 942 EKIMKELEIKEMMARHKQELTEKDATIASLEETN 975
Score = 28.9 bits (63), Expect = 9.9
Identities = 32/147 (21%), Positives = 58/147 (39%), Gaps = 13/147 (8%)
Query: 131 DVDHPLCEECTDTLLDQLDTQLNVTEN-----ECQNYKRCLEILE-QMNEDDSEQLQMEL 184
D D ++ + LL Q D N E + KRCL + +M L+M
Sbjct: 765 DCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSE 824
Query: 185 KELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELD 244
K+L E L++ ++EK + + + + + L + Q + +K Q EL
Sbjct: 825 KQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELK 884
Query: 245 DEL-------KSVENQMRYAQTQLDKL 264
+E K ++ + + Q + D L
Sbjct: 885 EECEEKTKLGKELQQKKQELQDERDSL 911
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 41/166 (24%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQM------ELKE 186
L EE D ++L T +L E +R ++++E D E++++ E K
Sbjct: 58 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 117
Query: 187 LALEEERLIQEL-------------------------EDVEKNRKIVAENLEKVQAEAER 221
+A E +R +E+ ++E+ K V NL+ ++A+AE+
Sbjct: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 177
Query: 222 LDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
Q+E +Y+ E L D+LK E + +A+ + KL+KT
Sbjct: 178 YSQKEDKYEEEIK-------ILTDKLKEAETRAEFAERSVAKLEKT 216
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 41/166 (24%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQM------ELKE 186
L EE D ++L T +L E +R ++++E D E++++ E K
Sbjct: 58 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 117
Query: 187 LALEEERLIQEL-------------------------EDVEKNRKIVAENLEKVQAEAER 221
+A E +R +E+ ++E+ K V NL+ ++A+AE+
Sbjct: 118 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 177
Query: 222 LDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
Q+E +Y+ E L D+LK E + +A+ + KL+KT
Sbjct: 178 YSQKEDKYEEEIK-------ILTDKLKEAETRAEFAERSVAKLEKT 216
Score = 37.0 bits (84), Expect = 0.037
Identities = 27/128 (21%), Positives = 60/128 (46%), Gaps = 10/128 (7%)
Query: 139 ECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQM---ELKELALEEERLI 195
E D +++ +L + E + + + E+ E + E+L+ LK L + E+
Sbjct: 120 EEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 179
Query: 196 QELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMR 255
Q+ + E+ KI+ + L++ + AE ++ A+ ++ + L+D+LK + +
Sbjct: 180 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD-------LEDKLKCTKEEHL 232
Query: 256 YAQTQLDK 263
Q LD+
Sbjct: 233 CTQRMLDQ 240
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 41/166 (24%)
Query: 136 LCEECTDTLLDQLDT---QLNVTENECQNYKRCLEILEQMNEDDSEQLQM------ELKE 186
L EE D ++L T +L E +R ++++E D E++++ E K
Sbjct: 95 LVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 154
Query: 187 LALEEERLIQEL-------------------------EDVEKNRKIVAENLEKVQAEAER 221
+A E +R +E+ ++E+ K V NL+ ++A+AE+
Sbjct: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
Query: 222 LDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
Q+E +Y+ E L D+LK E + +A+ + KL+KT
Sbjct: 215 YSQKEDKYEEEIKI-------LTDKLKEAETRAEFAERSVAKLEKT 253
Score = 32.7 bits (73), Expect = 0.69
Identities = 22/99 (22%), Positives = 48/99 (48%), Gaps = 7/99 (7%)
Query: 175 DDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEK-------VQAEAERLDQEEA 227
D +EQ + E K+ ++L EL ++K K + L+K Q + E +++ A
Sbjct: 21 DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAA 80
Query: 228 QYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+ E + R+ +++EL + ++ A +L++ +K
Sbjct: 81 DAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 119
Score = 29.6 bits (65), Expect = 5.8
Identities = 13/75 (17%), Positives = 41/75 (54%)
Query: 192 ERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVE 251
E + ++++ ++ +++ + E+ +AE ++ ++ Q + E + +++ +DEL
Sbjct: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
Query: 252 NQMRYAQTQLDKLKK 266
++ AQ +L+ +K
Sbjct: 63 EALKDAQEKLELAEK 77
Score = 28.9 bits (63), Expect = 9.9
Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 21/128 (16%)
Query: 129 QTDVDHPLCEECTDTLLDQL---DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELK 185
Q + + EE + L D+L +L TE+E Y L+ D E+L++ K
Sbjct: 25 QAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK-------DAQEKLELAEK 77
Query: 186 ELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
+ A E E+ + + ++V E L++ Q ERL A ++ E ++ E +
Sbjct: 78 KAADAEA----EVASLNRRIQLVEEELDRAQ---ERL----ATALQKLEEAEKAADESER 126
Query: 246 ELKSVENQ 253
+K +EN+
Sbjct: 127 GMKVIENR 134
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 46.6 bits (109), Expect = 5e-05
Identities = 31/122 (25%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Query: 149 DTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLI---QELEDVEKNR 205
+ ++ + E + + K E ++ E+ + +L + EL EER + D+E+
Sbjct: 138 EEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEEL 197
Query: 206 KIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLK 265
KIV NL+ ++A+A++ +E +Y+ E L+++LK E + +A+ + KL+
Sbjct: 198 KIVTNNLKSLEAQADKYSTKEDKYEEEIK-------LLEEKLKEAETRAEFAERSVAKLE 250
Query: 266 KT 267
KT
Sbjct: 251 KT 252
Score = 30.8 bits (68), Expect = 2.6
Identities = 21/111 (18%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 146 DQLDTQLNVTENECQNYKRCLEILEQM---NEDDSEQLQMELKELALEEERLIQELEDVE 202
+Q + E+ C+ + + L++ ED+ E+ +KE + E+ ++ D E
Sbjct: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAE 82
Query: 203 KNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQ 253
+ + ++ V+ E +R + A ++ E ++ E + +K +EN+
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/99 (18%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 175 DDSEQLQME-------LKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEA 227
D +EQ + + K+L E++ L ++L+ E + +E++++ Q + E+ +++
Sbjct: 20 DRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKAT 79
Query: 228 QYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKK 266
+ + + R+ +++EL + ++ A +L++ +K
Sbjct: 80 DAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,512,210
Number of Sequences: 37866
Number of extensions: 742355
Number of successful extensions: 10017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 432
Number of HSP's successfully gapped in prelim test: 605
Number of HSP's that attempted gapping in prelim test: 4772
Number of HSP's gapped (non-prelim): 4407
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.