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Search of human proteins with 4502081
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502081 amphiphysin isoform 1 [Homo sapiens]
(695 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 1387 0.0
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 1286 0.0
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens] 461 e-129
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 439 e-123
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 434 e-121
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 424 e-118
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens] 377 e-104
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 369 e-102
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 367 e-101
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 367 e-101
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 357 2e-98
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens] 353 3e-97
gi|49472835 bridging integrator 2 [Homo sapiens] 302 6e-82
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 71 4e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 71 4e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 71 4e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 71 4e-12
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 70 9e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 57 6e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 57 6e-08
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 56 1e-07
gi|39930351 dynamin binding protein [Homo sapiens] 55 2e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 55 2e-07
gi|116284392 mucin 2 precursor [Homo sapiens] 54 6e-07
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 54 6e-07
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 52 1e-06
gi|8923904 bridging integrator 3 [Homo sapiens] 51 3e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 51 3e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 50 5e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 50 7e-06
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 1387 bits (3590), Expect = 0.0
Identities = 695/695 (100%), Positives = 695/695 (100%)
Query: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
Sbjct: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
Query: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
Sbjct: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
Query: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
Sbjct: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
Query: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
Sbjct: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
Query: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
Sbjct: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
Sbjct: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
Query: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
Sbjct: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
Query: 421 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL 480
ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
Sbjct: 421 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL 480
Query: 481 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 540
VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
Sbjct: 481 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 540
Query: 541 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 600
PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
Sbjct: 541 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 600
Query: 601 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 660
PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
Sbjct: 601 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 660
Query: 661 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 695
DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
Sbjct: 661 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 695
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 1286 bits (3327), Expect = 0.0
Identities = 653/695 (93%), Positives = 653/695 (93%), Gaps = 42/695 (6%)
Query: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
Sbjct: 1 MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL 60
Query: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
Sbjct: 61 RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT 120
Query: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
Sbjct: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
Query: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
Sbjct: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD 240
Query: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
Sbjct: 241 KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG 300
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
Sbjct: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
Query: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
Sbjct: 361 PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM 420
Query: 421 ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL 480
ICNL IIPGADADAAVGTL
Sbjct: 421 ICNL------------------------------------------IIPGADADAAVGTL 438
Query: 481 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 540
VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
Sbjct: 439 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 498
Query: 541 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 600
PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
Sbjct: 499 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 558
Query: 601 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 660
PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
Sbjct: 559 PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ 618
Query: 661 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 695
DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
Sbjct: 619 DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD 653
>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
Length = 593
Score = 461 bits (1186), Expect = e-129
Identities = 274/622 (44%), Positives = 356/622 (57%), Gaps = 72/622 (11%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
Query: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212
AEEE KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
Query: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272
E FHKE++ L L +V+ L QH FT++ PSD+ P + K+PSPP + SP +
Sbjct: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
Query: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFV 329
P NH P A+P P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FV
Sbjct: 308 PEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFV 367
Query: 330 PEISVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTS 388
PEISVTTPSQ E P ++ +LLDLDFDP P +P + +P Q++PWDLW
Sbjct: 368 PEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW--- 420
Query: 389 TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAV 448
+ + +G +G + + Q+ +E P +A E PA
Sbjct: 421 -EPTESPAGSLPSGEPSAAEGTFAVSWPSQT-------AEPGPAQPAEASEVAGGTQPAA 472
Query: 449 GLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLE 508
G +T A E + +P + T+ EG G A + +P G ++
Sbjct: 473 GAQEPGETAASEAASSS--LPAVVVETFPATVNGTVEGGSG----AGRLDLPPGFMFKVQ 526
Query: 509 EAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKET 568
T T + +EL Q K V++ P N EE+ E + +G + +
Sbjct: 527 AQHDYTAT---------DTDEL-----QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDW 571
Query: 569 TEDAAPPGPTSETPELATEQKP 590
+ PE TE+ P
Sbjct: 572 NQHKELEKCRGVFPENFTERVP 593
Score = 114 bits (284), Expect = 4e-25
Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)
Query: 496 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 555
KA P+G+ + + E TE + P E A PS EP E
Sbjct: 406 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 461
Query: 556 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 611
+E+ G +P +E E AA +S P + E P G D
Sbjct: 462 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 516
Query: 612 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 671
LPPGF++KV+ HD+ A ++DEL L+ GDVVLV+P + +QD GWL+GVKES
Sbjct: 517 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 569
Query: 672 DWLQYRDLATYKGLFPENFTRRL 694
DW Q+++L +G+FPENFT R+
Sbjct: 570 DWNQHKELEKCRGVFPENFTERV 592
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 439 bits (1129), Expect = e-123
Identities = 230/409 (56%), Positives = 279/409 (68%), Gaps = 28/409 (6%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ RKG
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 307
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK 360
PPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 308 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ--------------------- 346
Query: 361 PEVTPAGSAGVTHSPMSQ---TLPWDLWTTSTDLVQPASGGSFNGFTQP 406
P +PAGS ++ + W T QPA G TQP
Sbjct: 347 PTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQP 395
Score = 111 bits (278), Expect = 2e-24
Identities = 86/283 (30%), Positives = 124/283 (43%), Gaps = 35/283 (12%)
Query: 427 SEQAPPTEPKAEEP---LAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSA 483
S+ AP K+ P A TP + ++ EP PGA + L
Sbjct: 255 SDNAPAKGNKSPSPPDGSPAATPEIRVN-------HEPEPAGGATPGATLPKSPSQLRKG 307
Query: 484 A------EGAPGEEAEAEKATVPAGEGVSLEEAKIGT--ETTEGAESAQPEAEELEATVP 535
+ P +E + E+ + E + E + T + TE + P E A
Sbjct: 308 PPVPPPPKHTPSKEVKQEQI-LSLFEDTFVPEISVTTPSQPTESPAGSLPSGEPSAAEGT 366
Query: 536 QEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPI 591
PS EP E +E+ G +P +E E AA +S P + E P
Sbjct: 367 FAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPA 425
Query: 592 QDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLV 651
G D LPPGF++KV+ HD+ A ++DEL L+ GDVVLV
Sbjct: 426 TVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLV 474
Query: 652 VPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694
+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 475 IPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 517
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 434 bits (1117), Expect = e-121
Identities = 216/339 (63%), Positives = 261/339 (76%), Gaps = 4/339 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ RKG
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKG 307
Query: 301 PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339
PPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 308 PPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 346
Score = 111 bits (277), Expect = 3e-24
Identities = 76/241 (31%), Positives = 110/241 (45%), Gaps = 28/241 (11%)
Query: 469 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 525
P +A A S +G+P E P G + A K ++ +G P
Sbjct: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 313
Query: 526 EAEELEATVPQEKV--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAA 573
V QE++ +P + + +PA E G + GA+ E E AA
Sbjct: 314 PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAA 371
Query: 574 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 633
+S P + E P G D LPPGF++KV+ HD+
Sbjct: 372 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 420
Query: 634 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 693
A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R
Sbjct: 421 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 480
Query: 694 L 694
+
Sbjct: 481 V 481
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 424 bits (1091), Expect = e-118
Identities = 216/354 (61%), Positives = 261/354 (73%), Gaps = 19/354 (5%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285
T++ P SD+ P + K+PSPP + SP +P NH P A+
Sbjct: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
Query: 286 PAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339
P P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 308 PGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 361
Score = 109 bits (273), Expect = 7e-24
Identities = 73/228 (32%), Positives = 106/228 (46%), Gaps = 28/228 (12%)
Query: 482 SAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQPEAEELEATVPQEK 538
S +G+P E P G + A K ++ +G P V QE+
Sbjct: 282 SPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQ 341
Query: 539 V--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELAT 586
+ +P + + +PA E G + GA+ E E AA +S P +
Sbjct: 342 ILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPAVVV 399
Query: 587 EQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRG 646
E P G D LPPGF++KV+ HD+ A ++DEL L+ G
Sbjct: 400 ETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKAG 448
Query: 647 DVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694
DVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 449 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 496
>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
Length = 550
Score = 377 bits (969), Expect = e-104
Identities = 244/619 (39%), Positives = 322/619 (52%), Gaps = 109/619 (17%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
Query: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212
AEEE KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
Query: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272
E FHKE++ L L +V+ L QH FT++ PSD+ P + K+PSPP + SP +
Sbjct: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
Query: 273 PTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEI 332
P NH P PA +P T LPK
Sbjct: 308 PEIRVNH-----EPEPAGGATPGAT--------LPK------------------------ 330
Query: 333 SVTTPSQNEVP-EVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDL 391
+PSQ E P ++ +LLDLDFDP P +P + +P Q++PWDLW +
Sbjct: 331 ---SPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAP----TPSGQSIPWDLW----EP 379
Query: 392 VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLD 451
+ +G +G + + Q+ +E P +A E PA G
Sbjct: 380 TESPAGSLPSGEPSAAEGTFAVSWPSQT-------AEPGPAQPAEASEVAGGTQPAAGAQ 432
Query: 452 LGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAK 511
+T A E + +P + T+ EG G A + +P G ++
Sbjct: 433 EPGETAASEAASSS--LPAVVVETFPATVNGTVEGGSG----AGRLDLPPGFMFKVQAQH 486
Query: 512 IGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTED 571
T T + +EL Q K V++ P N EE+ E + +G + + +
Sbjct: 487 DYTAT---------DTDEL-----QLKAGDVVLVIPFQNPEEQDEGWL-MGVKESDWNQH 531
Query: 572 AAPPGPTSETPELATEQKP 590
PE TE+ P
Sbjct: 532 KELEKCRGVFPENFTERVP 550
Score = 114 bits (284), Expect = 4e-25
Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 20/203 (9%)
Query: 496 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 555
KA P+G+ + + E TE + P E A PS EP E
Sbjct: 363 KAPTPSGQSIPWDL----WEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA 418
Query: 556 ENEITIGAEP----KETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLAS 611
+E+ G +P +E E AA +S P + E P G D
Sbjct: 419 -SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD---- 473
Query: 612 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 671
LPPGF++KV+ HD+ A ++DEL L+ GDVVLV+P + +QD GWL+GVKES
Sbjct: 474 -------LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 526
Query: 672 DWLQYRDLATYKGLFPENFTRRL 694
DW Q+++L +G+FPENFT R+
Sbjct: 527 DWNQHKELEKCRGVFPENFTERV 549
>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
Length = 475
Score = 369 bits (948), Expect = e-102
Identities = 184/301 (61%), Positives = 226/301 (75%), Gaps = 4/301 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ +
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTES 307
Query: 301 P 301
P
Sbjct: 308 P 308
Score = 114 bits (285), Expect = 3e-25
Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Query: 469 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 525
P +A A S +G+P E P G + A K ++ TE + P
Sbjct: 254 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLP 313
Query: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSET 581
E A PS EP E +E+ G +P +E E AA +S
Sbjct: 314 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSL 372
Query: 582 PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 641
P + E P G D LPPGF++KV+ HD+ A ++DEL
Sbjct: 373 PAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDEL 421
Query: 642 TLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694
L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 422 QLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 474
>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
Length = 409
Score = 367 bits (943), Expect = e-101
Identities = 183/297 (61%), Positives = 225/297 (75%), Gaps = 4/297 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQT 297
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ+
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQS 304
Score = 110 bits (276), Expect = 3e-24
Identities = 59/168 (35%), Positives = 87/168 (51%), Gaps = 25/168 (14%)
Query: 552 EEEGENEITIGAEPKETT------EDAAPPGPTSETPELATEQKPIQDPQPTPSA----- 600
++ G N T+ A+P + + P G + TPE+ +P TP A
Sbjct: 241 KQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKS 300
Query: 601 --------------PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRG 646
PA + +LPPGF++KV+ HD+ A ++DEL L+ G
Sbjct: 301 PSQSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAG 360
Query: 647 DVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694
DVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 361 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 408
>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
Length = 439
Score = 367 bits (943), Expect = e-101
Identities = 184/303 (60%), Positives = 226/303 (74%), Gaps = 4/303 (1%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---ASPAPARPRSPSQTRKG 300
T++ PSD+ P + K+PSPP + SP +P NH P A+P P+SPSQ +
Sbjct: 249 TVKAQPSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPAEA 307
Query: 301 PPV 303
V
Sbjct: 308 SEV 310
Score = 113 bits (282), Expect = 7e-25
Identities = 74/229 (32%), Positives = 108/229 (47%), Gaps = 26/229 (11%)
Query: 467 IIPGADADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESAQP 525
++ G + T A+ + A+ K+ + P G + E ++ E E A A P
Sbjct: 235 VLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP-EPAGGATP 293
Query: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELA 585
A +P +PA E G + GA+ E E AA +S P +
Sbjct: 294 GA-----------TLPKSPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPAVV 340
Query: 586 TEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQR 645
E P G D LPPGF++KV+ HD+ A ++DEL L+
Sbjct: 341 VETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKA 389
Query: 646 GDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694
GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 390 GDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 438
>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
Length = 454
Score = 357 bits (917), Expect = 2e-98
Identities = 184/318 (57%), Positives = 226/318 (71%), Gaps = 19/318 (5%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE KAQKVFEE
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243
NVDLQEELPSLW+ RVGFYVNTF++++ LE FHKE++ L L +V+ L QH F
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
Query: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285
T++ P SD+ P + K+PSPP + SP +P NH P A+
Sbjct: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
Query: 286 PAPARPRSPSQTRKGPPV 303
P P+SPSQ + V
Sbjct: 308 PGATLPKSPSQPAEASEV 325
Score = 112 bits (279), Expect = 2e-24
Identities = 64/181 (35%), Positives = 92/181 (50%), Gaps = 16/181 (8%)
Query: 518 EGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAA 573
+G+ +A PE P P + P S + +E+ G +P +E E AA
Sbjct: 285 DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQPAEASEVAGGTQPAAGAQEPGETAA 343
Query: 574 PPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDF 633
+S P + E P G D LPPGF++KV+ HD+
Sbjct: 344 SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDY 392
Query: 634 EAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRR 693
A ++DEL L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R
Sbjct: 393 TATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTER 452
Query: 694 L 694
+
Sbjct: 453 V 453
>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
Length = 506
Score = 353 bits (906), Expect = 3e-97
Identities = 184/332 (55%), Positives = 226/332 (68%), Gaps = 35/332 (10%)
Query: 4 IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63
+ G A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q EGTRLQ++LR Y
Sbjct: 9 VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
Query: 64 LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123
LA++K M EAS KL E L EVYEPDW GR++ + E D+LW D+HQKLVD +LLT+DT
Sbjct: 69 LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
Query: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISK--------------- 168
YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+K
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQG 188
Query: 169 ----------------AEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSL 212
AEEE KAQKVFEE NVDLQEELPSLW+ RVGFYVNTF++++ L
Sbjct: 189 KLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGL 248
Query: 213 EAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPS 272
E FHKE++ L L +V+ L QH FT++ PSD+ P + K+PSPP + SP +
Sbjct: 249 EENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP-DGSPAAT 307
Query: 273 PTASPNHTLAP---ASPAPARPRSPSQTRKGP 301
P NH P A+P P+SPSQ + P
Sbjct: 308 PEIRVNHEPEPAGGATPGATLPKSPSQPTESP 339
Score = 114 bits (285), Expect = 3e-25
Identities = 77/233 (33%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Query: 469 PGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQP 525
P +A A S +G+P E P G + A K ++ TE + P
Sbjct: 285 PSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQPTESPAGSLP 344
Query: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEP----KETTEDAAPPGPTSET 581
E A PS EP E +E+ G +P +E E AA +S
Sbjct: 345 SGEPSAAEGTFAVSWPSQTAEPGPAQPAEA-SEVAGGTQPAAGAQEPGETAASEAASSSL 403
Query: 582 PELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 641
P + E P G D LPPGF++KV+ HD+ A ++DEL
Sbjct: 404 PAVVVETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDEL 452
Query: 642 TLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694
L+ GDVVLV+P + +QD GWL+GVKESDW Q+++L +G+FPENFT R+
Sbjct: 453 QLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 505
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 302 bits (774), Expect = 6e-82
Identities = 196/558 (35%), Positives = 297/558 (53%), Gaps = 30/558 (5%)
Query: 7 GIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAA 66
G+FAK VQK+ +RAQEKVLQKLGKA ETKDE+FE+ NF +Q+AEG +L ++L+ +L+A
Sbjct: 11 GLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSA 70
Query: 67 IKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLG 126
+K M E+S +++E+L E+Y +W G E++K + D+LWED+ +KL D ++ T++ Y+
Sbjct: 71 VKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVA 130
Query: 127 QFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVD 186
QF +IK RIAKR RKLVDYDSARHHLEA+Q++K+KDE++ +KAEEEF KAQ VFE+ N +
Sbjct: 131 QFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQE 190
Query: 187 LQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQ 246
L EELP L++ R+G YV F+N+S+L F++E++ L H LYEVM+KL QH++K F ++
Sbjct: 191 LLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSNKVFVVK 250
Query: 247 GAPSDSGPLRIAKTPSPPEE----PSPLPSPTASPNHTLAPASPA-PARPRSPSQTRKGP 301
G S S R + SPP SPL SPT+ +L S + A +G
Sbjct: 251 GLSSSS---RRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGE 307
Query: 302 PVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP 361
+ ++ +E+++E + + P + P+Q + P E + P
Sbjct: 308 DNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNGPAQAQ-PSPTTERAKSQEEVLPSST 366
Query: 362 EVTPAGSAGVTHSPMSQTLPWDL--WTTSTDLVQPASGGSFNGFTQPQD------TSLFT 413
+P G+ + P S L T S QP S + P +
Sbjct: 367 TPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASP 426
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADA 473
+ ++ + S PT P+A +P L++ + EP E+ V P A
Sbjct: 427 RPSSGNIPSSPTASGGGSPTSPRASLGTGTASPRTSLEVSPN---PEPPEKPVRTPEAKE 483
Query: 474 DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAK-----IGTETTEGAESAQ---- 524
+ + + E + GE +E+ + I ++EG + Q
Sbjct: 484 NENIHN-QNPEELCTSPTLMTSQVASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMV 542
Query: 525 PEAEELEATVPQEKVIPS 542
PE L A PQE+V S
Sbjct: 543 PENNNLTAPEPQEEVSTS 560
Score = 32.7 bits (73), Expect = 1.2
Identities = 54/251 (21%), Positives = 88/251 (35%), Gaps = 24/251 (9%)
Query: 386 TTSTDLVQPASGGSFNGFTQPQDTSLF-------TMQTDQSMICNLAESEQ-----APPT 433
T S+ L P S + + ++ + S D S I L E E+ + +
Sbjct: 270 TVSSPLTSPTSPSTLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEAS 329
Query: 434 EPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA- 492
+ +EPL A T + EE ++P + + G L + G P A
Sbjct: 330 SSEEDEPLPACNGPAQAQPSPTTERAKSQEE--VLPSSTTPSPGGAL--SPSGQPSSSAT 385
Query: 493 EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHE 552
E T A EG + + + T S P + P IPS
Sbjct: 386 EVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTASGGGSP 445
Query: 553 EEGENEITIG-AEPK---ETTEDAAPPGPTSETPELATEQKPI--QDPQPTPSAPAMGAA 606
+ G A P+ E + + PP TPE A E + I Q+P+ ++P + +
Sbjct: 446 TSPRASLGTGTASPRTSLEVSPNPEPPEKPVRTPE-AKENENIHNQNPEELCTSPTLMTS 504
Query: 607 DQLASAREASQ 617
+ EA +
Sbjct: 505 QVASEPGEAKK 515
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 70.9 bits (172), Expect = 4e-12
Identities = 93/364 (25%), Positives = 128/364 (35%), Gaps = 49/364 (13%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 330
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 331 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 383
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE 434
+ P T S T +PA + + T P++ S T +++ PT
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-------------TKEPAPTT 430
Query: 435 PKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA-E 493
PK P PA T +EP P + A T A P E A
Sbjct: 431 PKEPAPTTPKKPA-------PTTPKEPA------PTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
K T P T + A EEL T P+E P+ EPA +
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT-PTTPEEPAPTTPK 536
Query: 554 EG------ENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 606
E T EP TT ++ AP P P P +P P+ P A
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 607 DQLA 610
+LA
Sbjct: 597 KELA 600
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/385 (23%), Positives = 133/385 (34%), Gaps = 47/385 (12%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA-----SPAPARPRSPSQTRKGPPV 303
P + P I P+ P+EP+P + +A P PA PAP P+ P+ T P
Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 287
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPE- 362
P K PT + P+ T + P KE + P P+
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347
Query: 363 ---VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
P A T + T P + T+T P T P++ + T ++ +
Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---------TTPKEPAPTTTKSAPT 398
Query: 420 MICNLA-ESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVG 478
A + ++ PT PK P PA P E A P A
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----------PTTPKEPAPTTPKKPAP---- 444
Query: 479 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 538
+ E AP E T + +E T E+A ++L T P EK
Sbjct: 445 --TTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTP-EK 497
Query: 539 VIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPT 597
+ P+ +PA E E T EP TT E+ AP P + P E P +P
Sbjct: 498 LAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 555
Query: 598 PSAPAMGAADQLASAREASQELPPG 622
P+ P A + +E + P G
Sbjct: 556 PTTPKEPAP---TTPKETAPTTPKG 577
Score = 64.7 bits (156), Expect = 3e-10
Identities = 98/395 (24%), Positives = 137/395 (34%), Gaps = 53/395 (13%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 456
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-------- 508
Query: 403 FTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPV 462
T P++ + T + E+ PT PKA P PA + P
Sbjct: 509 -TTPEELAPTTPEEPTP-----TTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPK 560
Query: 463 EEAVIIPGADA-----DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETT 517
E A P A A TL A P + A E A E S K T
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Query: 518 EGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEPKE 567
+G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 621 KGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678
Query: 568 TTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 601
TT D AP P P E P +P P+ P
Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713
Score = 57.8 bits (138), Expect = 3e-08
Identities = 94/399 (23%), Positives = 138/399 (34%), Gaps = 70/399 (17%)
Query: 249 PSDSGPLRIAK-TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLP 307
P + P K P+ P+EP+P +P T PAP P+ P+ T P P
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPKETAPTTP 487
Query: 308 K-VTPTKELQQENIISFFEDNFVP----EISVTTPSQNEVPEVKKEETLLDLDFDPFKPE 362
K +TPT E + + P E++ TTP + ++ P P+
Sbjct: 488 KKLTPTTP---EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 544
Query: 363 ----VTPAGSAGVTHSPMSQTLPWDLWTTS------TDLVQPASGGSFNGFTQPQDTSLF 412
TP A T + T P + T+ T L +PA P++ +
Sbjct: 545 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPT 602
Query: 413 TMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGAD 472
T + S C ++ PT PK P PA T +EP P
Sbjct: 603 TTKEPTSTTC-----DKPAPTTPKGTAPTTPKEPA-------PTTPKEPA------PTTP 644
Query: 473 ADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESAQ------- 524
A TL A P + A E A T G + + T E A +
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 704
Query: 525 -----PEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG- 576
P E E P+ EP + H+ E+ + AEP + +P PG
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 764
Query: 577 PTSETP------------ELATEQKPIQDPQPTPSAPAM 603
PT++TP + TE+ P+ T +AP M
Sbjct: 765 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Score = 51.2 bits (121), Expect = 3e-06
Identities = 75/385 (19%), Positives = 135/385 (35%), Gaps = 33/385 (8%)
Query: 244 TIQGAPSDSGPLRIAK-TPSPPEEPSP---LPSPTASPNHTL----APASP---APARPR 292
T P + P + + P+ P++P+P P+ T P T AP +P AP P+
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 293 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL 352
P+ T P P PK T L+ E + TTP + E+ T
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLK--------------EPAPTTPKKPAPKELAPTTTKG 675
Query: 353 DLDFDPFKPE-VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
KP TP +A T + T P T+ + P + T + T++
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 735
Query: 412 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA 471
+ + + + +A PK TPA M T A++ E +
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTP 794
Query: 472 DADAAVGTLVSAAEGAPGEEAEAE-KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEEL 530
+ A + + E++ AT + ++ TT + P+
Sbjct: 795 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 854
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
+ T+ +++ E + ++ N +P++ T+ P T + + +KP
Sbjct: 855 KKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 912
Query: 591 IQDPQP---TPSAPAMGAADQLASA 612
P P T + P + ++A A
Sbjct: 913 KTTPTPRKMTSTMPELNPTSRIAEA 937
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 70.9 bits (172), Expect = 4e-12
Identities = 93/364 (25%), Positives = 128/364 (35%), Gaps = 49/364 (13%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 371
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 372 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 424
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE 434
+ P T S T +PA + + T P++ S T +++ PT
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-------------TKEPAPTT 471
Query: 435 PKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA-E 493
PK P PA T +EP P + A T A P E A
Sbjct: 472 PKEPAPTTPKKPA-------PTTPKEPA------PTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
K T P T + A EEL T P+E P+ EPA +
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT-PTTPEEPAPTTPK 577
Query: 554 EG------ENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 606
E T EP TT ++ AP P P P +P P+ P A
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 607 DQLA 610
+LA
Sbjct: 638 KELA 641
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/385 (23%), Positives = 133/385 (34%), Gaps = 47/385 (12%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA-----SPAPARPRSPSQTRKGPPV 303
P + P I P+ P+EP+P + +A P PA PAP P+ P+ T P
Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 328
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPE- 362
P K PT + P+ T + P KE + P P+
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388
Query: 363 ---VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
P A T + T P + T+T P T P++ + T ++ +
Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---------TTPKEPAPTTTKSAPT 439
Query: 420 MICNLA-ESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVG 478
A + ++ PT PK P PA P E A P A
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----------PTTPKEPAPTTPKKPAP---- 485
Query: 479 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 538
+ E AP E T + +E T E+A ++L T P EK
Sbjct: 486 --TTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTP-EK 538
Query: 539 VIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPT 597
+ P+ +PA E E T EP TT E+ AP P + P E P +P
Sbjct: 539 LAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 596
Query: 598 PSAPAMGAADQLASAREASQELPPG 622
P+ P A + +E + P G
Sbjct: 597 PTTPKEPAP---TTPKETAPTTPKG 618
Score = 64.7 bits (156), Expect = 3e-10
Identities = 98/395 (24%), Positives = 137/395 (34%), Gaps = 53/395 (13%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 497
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-------- 549
Query: 403 FTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPV 462
T P++ + T + E+ PT PKA P PA + P
Sbjct: 550 -TTPEELAPTTPEEPTP-----TTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPK 601
Query: 463 EEAVIIPGADA-----DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETT 517
E A P A A TL A P + A E A E S K T
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Query: 518 EGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEPKE 567
+G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 662 KGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719
Query: 568 TTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 601
TT D AP P P E P +P P+ P
Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754
Score = 57.8 bits (138), Expect = 3e-08
Identities = 94/399 (23%), Positives = 138/399 (34%), Gaps = 70/399 (17%)
Query: 249 PSDSGPLRIAK-TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLP 307
P + P K P+ P+EP+P +P T PAP P+ P+ T P P
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPKETAPTTP 528
Query: 308 K-VTPTKELQQENIISFFEDNFVP----EISVTTPSQNEVPEVKKEETLLDLDFDPFKPE 362
K +TPT E + + P E++ TTP + ++ P P+
Sbjct: 529 KKLTPTTP---EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 585
Query: 363 ----VTPAGSAGVTHSPMSQTLPWDLWTTS------TDLVQPASGGSFNGFTQPQDTSLF 412
TP A T + T P + T+ T L +PA P++ +
Sbjct: 586 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPT 643
Query: 413 TMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGAD 472
T + S C ++ PT PK P PA T +EP P
Sbjct: 644 TTKEPTSTTC-----DKPAPTTPKGTAPTTPKEPA-------PTTPKEPA------PTTP 685
Query: 473 ADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESAQ------- 524
A TL A P + A E A T G + + T E A +
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 745
Query: 525 -----PEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG- 576
P E E P+ EP + H+ E+ + AEP + +P PG
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 805
Query: 577 PTSETP------------ELATEQKPIQDPQPTPSAPAM 603
PT++TP + TE+ P+ T +AP M
Sbjct: 806 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Score = 51.2 bits (121), Expect = 3e-06
Identities = 75/385 (19%), Positives = 135/385 (35%), Gaps = 33/385 (8%)
Query: 244 TIQGAPSDSGPLRIAK-TPSPPEEPSP---LPSPTASPNHTL----APASP---APARPR 292
T P + P + + P+ P++P+P P+ T P T AP +P AP P+
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 293 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL 352
P+ T P P PK T L+ E + TTP + E+ T
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLK--------------EPAPTTPKKPAPKELAPTTTKG 716
Query: 353 DLDFDPFKPE-VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
KP TP +A T + T P T+ + P + T + T++
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 776
Query: 412 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA 471
+ + + + +A PK TPA M T A++ E +
Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTP 835
Query: 472 DADAAVGTLVSAAEGAPGEEAEAE-KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEEL 530
+ A + + E++ AT + ++ TT + P+
Sbjct: 836 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 895
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
+ T+ +++ E + ++ N +P++ T+ P T + + +KP
Sbjct: 896 KKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 953
Query: 591 IQDPQP---TPSAPAMGAADQLASA 612
P P T + P + ++A A
Sbjct: 954 KTTPTPRKMTSTMPELNPTSRIAEA 978
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 70.9 bits (172), Expect = 4e-12
Identities = 93/364 (25%), Positives = 128/364 (35%), Gaps = 49/364 (13%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 423
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 424 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 476
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE 434
+ P T S T +PA + + T P++ S T +++ PT
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-------------TKEPAPTT 523
Query: 435 PKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA-E 493
PK P PA T +EP P + A T A P E A
Sbjct: 524 PKEPAPTTPKKPA-------PTTPKEPA------PTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
K T P T + A EEL T P+E P+ EPA +
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT-PTTPEEPAPTTPK 629
Query: 554 EG------ENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 606
E T EP TT ++ AP P P P +P P+ P A
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 607 DQLA 610
+LA
Sbjct: 690 KELA 693
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/385 (23%), Positives = 133/385 (34%), Gaps = 47/385 (12%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA-----SPAPARPRSPSQTRKGPPV 303
P + P I P+ P+EP+P + +A P PA PAP P+ P+ T P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 380
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPE- 362
P K PT + P+ T + P KE + P P+
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440
Query: 363 ---VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
P A T + T P + T+T P T P++ + T ++ +
Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---------TTPKEPAPTTTKSAPT 491
Query: 420 MICNLA-ESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVG 478
A + ++ PT PK P PA P E A P A
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----------PTTPKEPAPTTPKKPAP---- 537
Query: 479 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 538
+ E AP E T + +E T E+A ++L T P EK
Sbjct: 538 --TTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTP-EK 590
Query: 539 VIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPT 597
+ P+ +PA E E T EP TT E+ AP P + P E P +P
Sbjct: 591 LAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 648
Query: 598 PSAPAMGAADQLASAREASQELPPG 622
P+ P A + +E + P G
Sbjct: 649 PTTPKEPAP---TTPKETAPTTPKG 670
Score = 64.7 bits (156), Expect = 3e-10
Identities = 98/395 (24%), Positives = 137/395 (34%), Gaps = 53/395 (13%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 549
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-------- 601
Query: 403 FTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPV 462
T P++ + T + E+ PT PKA P PA + P
Sbjct: 602 -TTPEELAPTTPEEPTP-----TTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPK 653
Query: 463 EEAVIIPGADA-----DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETT 517
E A P A A TL A P + A E A E S K T
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Query: 518 EGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEPKE 567
+G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 714 KGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 771
Query: 568 TTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 601
TT D AP P P E P +P P+ P
Sbjct: 772 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 806
Score = 57.8 bits (138), Expect = 3e-08
Identities = 94/399 (23%), Positives = 138/399 (34%), Gaps = 70/399 (17%)
Query: 249 PSDSGPLRIAK-TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLP 307
P + P K P+ P+EP+P +P T PAP P+ P+ T P P
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPKETAPTTP 580
Query: 308 K-VTPTKELQQENIISFFEDNFVP----EISVTTPSQNEVPEVKKEETLLDLDFDPFKPE 362
K +TPT E + + P E++ TTP + ++ P P+
Sbjct: 581 KKLTPTTP---EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 363 ----VTPAGSAGVTHSPMSQTLPWDLWTTS------TDLVQPASGGSFNGFTQPQDTSLF 412
TP A T + T P + T+ T L +PA P++ +
Sbjct: 638 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPT 695
Query: 413 TMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGAD 472
T + S C ++ PT PK P PA T +EP P
Sbjct: 696 TTKEPTSTTC-----DKPAPTTPKGTAPTTPKEPA-------PTTPKEPA------PTTP 737
Query: 473 ADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESAQ------- 524
A TL A P + A E A T G + + T E A +
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797
Query: 525 -----PEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG- 576
P E E P+ EP + H+ E+ + AEP + +P PG
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857
Query: 577 PTSETP------------ELATEQKPIQDPQPTPSAPAM 603
PT++TP + TE+ P+ T +AP M
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896
Score = 51.2 bits (121), Expect = 3e-06
Identities = 75/385 (19%), Positives = 135/385 (35%), Gaps = 33/385 (8%)
Query: 244 TIQGAPSDSGPLRIAK-TPSPPEEPSP---LPSPTASPNHTL----APASP---APARPR 292
T P + P + + P+ P++P+P P+ T P T AP +P AP P+
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722
Query: 293 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL 352
P+ T P P PK T L+ E + TTP + E+ T
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLK--------------EPAPTTPKKPAPKELAPTTTKG 768
Query: 353 DLDFDPFKPE-VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
KP TP +A T + T P T+ + P + T + T++
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828
Query: 412 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA 471
+ + + + +A PK TPA M T A++ E +
Sbjct: 829 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTP 887
Query: 472 DADAAVGTLVSAAEGAPGEEAEAE-KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEEL 530
+ A + + E++ AT + ++ TT + P+
Sbjct: 888 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 947
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
+ T+ +++ E + ++ N +P++ T+ P T + + +KP
Sbjct: 948 KKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1005
Query: 591 IQDPQP---TPSAPAMGAADQLASA 612
P P T + P + ++A A
Sbjct: 1006 KTTPTPRKMTSTMPELNPTSRIAEA 1030
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 70.9 bits (172), Expect = 4e-12
Identities = 93/364 (25%), Positives = 128/364 (35%), Gaps = 49/364 (13%)
Query: 261 PSPPEEPSPL----PSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
P+ P+EP+P P+PT + + P PAP P+ P+ T P P PK PT
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTP 464
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPM 376
+E + E + TTP + KK + P P+ PA + SP
Sbjct: 465 KEPAPT------TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPT 517
Query: 377 SQTLPWDLWTTS--TDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE 434
+ P T S T +PA + + T P++ S T +++ PT
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-------------TKEPAPTT 564
Query: 435 PKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA-E 493
PK P PA T +EP P + A T A P E A
Sbjct: 565 PKEPAPTTPKKPA-------PTTPKEPA------PTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
K T P T + A EEL T P+E P+ EPA +
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT-PTTPEEPAPTTPK 670
Query: 554 EG------ENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAA 606
E T EP TT ++ AP P P P +P P+ P A
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 607 DQLA 610
+LA
Sbjct: 731 KELA 734
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/385 (23%), Positives = 133/385 (34%), Gaps = 47/385 (12%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPA-----SPAPARPRSPSQTRKGPPV 303
P + P I P+ P+EP+P + +A P PA PAP P+ P+ T P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 421
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPE- 362
P K PT + P+ T + P KE + P P+
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481
Query: 363 ---VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
P A T + T P + T+T P T P++ + T ++ +
Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---------TTPKEPAPTTTKSAPT 532
Query: 420 MICNLA-ESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVG 478
A + ++ PT PK P PA P E A P A
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----------PTTPKEPAPTTPKKPAP---- 578
Query: 479 TLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEK 538
+ E AP E T + +E T E+A ++L T P EK
Sbjct: 579 --TTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTP-EK 631
Query: 539 VIPSVVIEPASNHEEEGENEITIGAEPKETT-EDAAPPGPTSETPELATEQKPIQDPQPT 597
+ P+ +PA E E T EP TT E+ AP P + P E P +P
Sbjct: 632 LAPTTPEKPAPTTPE--ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 689
Query: 598 PSAPAMGAADQLASAREASQELPPG 622
P+ P A + +E + P G
Sbjct: 690 PTTPKEPAP---TTPKETAPTTPKG 711
Score = 64.7 bits (156), Expect = 3e-10
Identities = 98/395 (24%), Positives = 137/395 (34%), Gaps = 53/395 (13%)
Query: 240 DKAFTIQGAPSDSGPLRIAKT------PSPPEEPSPL----PSPTA--SPNHTLAPASPA 287
+ A T P+ + P + A T P+ P+EP+P PSPT P T ++P
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 288 PARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ +P+ T+ P P P T TKE P+ T + P K
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPK 590
Query: 348 E----ETLLDLDFDPFKP-EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNG 402
E T P +P TP +A T ++ T P L T+ + P
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-------- 642
Query: 403 FTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPV 462
T P++ + T + E+ PT PKA P PA + P
Sbjct: 643 -TTPEELAPTTPEEPTP-----TTPEEPAPTTPKAAAPNTPKEPAP--TTPKEPAPTTPK 694
Query: 463 EEAVIIPGADA-----DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETT 517
E A P A A TL A P + A E A E S K T
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Query: 518 EGAESAQPEAEELEATVPQEK-------VIPSVVIEPA-SNHEEEGENEI--TIGAEPKE 567
+G P +E T P+E P+ + EPA + ++ E+ T P
Sbjct: 755 KGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 812
Query: 568 TTED-AAPPGPTSETPELATEQKPIQDPQPTPSAP 601
TT D AP P P E P +P P+ P
Sbjct: 813 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 847
Score = 57.8 bits (138), Expect = 3e-08
Identities = 94/399 (23%), Positives = 138/399 (34%), Gaps = 70/399 (17%)
Query: 249 PSDSGPLRIAK-TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLP 307
P + P K P+ P+EP+P +P T PAP P+ P+ T P P
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPKETAPTTP 621
Query: 308 K-VTPTKELQQENIISFFEDNFVP----EISVTTPSQNEVPEVKKEETLLDLDFDPFKPE 362
K +TPT E + + P E++ TTP + ++ P P+
Sbjct: 622 KKLTPTTP---EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 363 ----VTPAGSAGVTHSPMSQTLPWDLWTTS------TDLVQPASGGSFNGFTQPQDTSLF 412
TP A T + T P + T+ T L +PA P++ +
Sbjct: 679 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPT 736
Query: 413 TMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGAD 472
T + S C ++ PT PK P PA T +EP P
Sbjct: 737 TTKEPTSTTC-----DKPAPTTPKGTAPTTPKEPA-------PTTPKEPA------PTTP 778
Query: 473 ADAAVGTLVSAAEGAPGEEAEAEKA-TVPAGEGVSLEEAKIGTETTEGAESAQ------- 524
A TL A P + A E A T G + + T E A +
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838
Query: 525 -----PEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP--PG- 576
P E E P+ EP + H+ E+ + AEP + +P PG
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898
Query: 577 PTSETP------------ELATEQKPIQDPQPTPSAPAM 603
PT++TP + TE+ P+ T +AP M
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937
Score = 51.2 bits (121), Expect = 3e-06
Identities = 75/385 (19%), Positives = 135/385 (35%), Gaps = 33/385 (8%)
Query: 244 TIQGAPSDSGPLRIAK-TPSPPEEPSP---LPSPTASPNHTL----APASP---APARPR 292
T P + P + + P+ P++P+P P+ T P T AP +P AP P+
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763
Query: 293 SPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL 352
P+ T P P PK T L+ E + TTP + E+ T
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLK--------------EPAPTTPKKPAPKELAPTTTKG 809
Query: 353 DLDFDPFKPE-VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
KP TP +A T + T P T+ + P + T + T++
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869
Query: 412 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA 471
+ + + + +A PK TPA M T A++ E +
Sbjct: 870 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP-EMTTTAKDKTTERDLRTTP 928
Query: 472 DADAAVGTLVSAAEGAPGEEAEAE-KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEEL 530
+ A + + E++ AT + ++ TT + P+
Sbjct: 929 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 988
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
+ T+ +++ E + ++ N +P++ T+ P T + + +KP
Sbjct: 989 KKTITTTEIMNKP--EETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1046
Query: 591 IQDPQP---TPSAPAMGAADQLASA 612
P P T + P + ++A A
Sbjct: 1047 KTTPTPRKMTSTMPELNPTSRIAEA 1071
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 69.7 bits (169), Expect = 9e-12
Identities = 107/434 (24%), Positives = 158/434 (36%), Gaps = 53/434 (12%)
Query: 239 ADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTR 298
A+ + +Q P++ PL + P+ + PS SP+ + P P+ SPS+
Sbjct: 310 AENSVKVQPPPAEEAPL--VEFPAEIQPPSAEESPSVELLAEILP----PSAEESPSEEP 363
Query: 299 KGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT--------TPSQNEVPEVKKEET 350
+PP + +P+ EL E I S E+ P++ E P V EET
Sbjct: 364 PAEILPPPAEKSPSVELLGE-IRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTV--EET 420
Query: 351 LLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTS 410
L D+ P PE P A + P + T+ P P++T+
Sbjct: 421 LADVQ--PLLPEEAPREEARELQLSTAMETPAE--EAPTEFQSPL----------PKETT 466
Query: 411 LFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPA------VGLDLGMDTRAEEPVEE 464
+ ++ A A T +A PL+ T A V L +T AEE E
Sbjct: 467 AEEASAEIQLLA--ATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAE 524
Query: 465 AVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATV----PAGEGVSLEEAKI------GT 514
++ +A A + A+ EE AE+A P+ +GVS+EEA + G
Sbjct: 525 IQLLAAIEAPA--DETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGE 582
Query: 515 ETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP 574
ETT AE A + L AT + P+ V P + P E A
Sbjct: 583 ETT--AEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE 640
Query: 575 PGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFE 634
P P A E P P APA A Q LP ETL
Sbjct: 641 EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVH 700
Query: 635 AANSDELTLQRGDV 648
+ +D++ + V
Sbjct: 701 SPPADDVPAEEASV 714
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 57.0 bits (136), Expect = 6e-08
Identities = 101/417 (24%), Positives = 151/417 (36%), Gaps = 56/417 (13%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPAS--PAPARPRSPSQTRKGPPVPPL 306
P+ P A PPEEP+ + +P +PA+ P P P SP+ P P
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Query: 307 PKV---TPTKELQQENIISFFEDNFVPEISVTTPSQNEVP--------EVKKEETLLDLD 355
P TP + + E+ P +V TP + P E +
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
Query: 356 FDPFKPE---VTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGF--TQPQDTS 410
+P P TP SA + ++ P + + + + PA SF T + TS
Sbjct: 1141 EEPAFPAPAVPTPEESAS---AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
Query: 411 -LFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIP 469
++ T +M+ L E + P +EEP A++ AV + EEP A +P
Sbjct: 1198 PAASVPTPAAMVATLEEFTSPAASVPTSEEP-ASLAAAV-------SNPEEPTSPAAAVP 1249
Query: 470 GADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEE 529
+ + SAA EE + A+VP E E A + E A P
Sbjct: 1250 TLEEPTS-----SAAAVLTPEELSSPAASVPTPE----EPASPAAAVSNLEEPASP---- 1296
Query: 530 LEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQK 589
A VP P V PA++ I A P E+ +P G T+
Sbjct: 1297 -AAAVP----TPEVAAIPAASVPTPEVPAIPAAAVP--PMEEVSPIGVPFLGVSAHTDSV 1349
Query: 590 PIQDPQPTP-----SAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDEL 641
PI + + TP S+ M + L S +E+ L+ L NSDE+
Sbjct: 1350 PISE-EGTPVLEEASSTGMWIKEDLDSLVFGIKEVTSTVLHGKVPLAATAGLNSDEV 1405
Score = 55.5 bits (132), Expect = 2e-07
Identities = 105/429 (24%), Positives = 143/429 (33%), Gaps = 61/429 (14%)
Query: 209 VSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDS---GPLRIAKTPSPPE 265
VSS E A + + + + A A T+ D GP+ A T PE
Sbjct: 926 VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPE 985
Query: 266 EPSPLPSPTASPNHTLAPAS--PAPARPRSPSQTRKGP--PVPPLPKVTPTKE-LQQENI 320
EP ++P +PA+ P P P SP+ P P P V P +E
Sbjct: 986 EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
Query: 321 ISFFEDNFVPEISVTTPSQNEVPEV---KKEETLLDLDFDPFKPEVTPAGSAGVTHSPMS 377
+ E+ P +V TP + P EE P E P A +P
Sbjct: 1046 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE--PTSPAAAVPTPEE 1103
Query: 378 QTLPWDLWTTSTDLVQPAS--------GGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQ 429
T P T + PA+ P++ + A +
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPE--ESASAAV 1161
Query: 430 APPTEPKAEEPLAAV-TPAVGLDL-GMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGA 487
A PT ++ P AAV TPA + EEP A +P AA A
Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP-----------TPAAMVA 1210
Query: 488 PGEEAEAEKATVPAG-EGVSLEEAKIGTETTEGAESAQPEAEELEAT-----VPQEKVIP 541
EE + A+VP E SL A E +A P EE ++ P+E P
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
Query: 542 SVVI----EPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPT 597
+ + EPAS A E+ A P TPE+A PT
Sbjct: 1271 AASVPTPEEPAS------------PAAAVSNLEEPASPAAAVPTPEVAAIPAA---SVPT 1315
Query: 598 PSAPAMGAA 606
P PA+ AA
Sbjct: 1316 PEVPAIPAA 1324
Score = 43.1 bits (100), Expect = 9e-04
Identities = 51/232 (21%), Positives = 72/232 (31%), Gaps = 22/232 (9%)
Query: 391 LVQPASGGSFNGFTQPQDTS----LFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
L P G S P+ T+ L + ++ ++ E+ T P A P
Sbjct: 851 LPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVP 910
Query: 447 AVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVS 506
AV V +P + AAV + S E AP A + + A G S
Sbjct: 911 AV----------------TVSVP--EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFS 952
Query: 507 LEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPK 566
E A + E PE AT P S EE + +
Sbjct: 953 PEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE 1012
Query: 567 ETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQE 618
T+ AA P P T A P + P + P A+A +E
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1064
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 57.0 bits (136), Expect = 6e-08
Identities = 79/353 (22%), Positives = 125/353 (35%), Gaps = 38/353 (10%)
Query: 263 PPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIIS 322
PP E P P A P T+ P P P + ++P+ K P +PP+ KE+ E +
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPPKKPVPEK-KAPAVVAKKPELPPVKVPEVPKEVVPEKKVP 10735
Query: 323 FFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPW 382
VP+ P+ +VPEV KE P KPEV PA V P+ + P
Sbjct: 10736 L----VVPKKPEAPPA--KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKP- 10788
Query: 383 DLWTTSTDLVQPASGGSFNGFTQPQDTS----LFTMQTDQSMICNLAESEQAPPTEPKAE 438
+ + + A + +P++ + + + + E E PP P+
Sbjct: 10789 -----AVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP 10843
Query: 439 EPLAAVTPAVGLDLGMDTRAEEPVEEAVI-----------IPGADADAAVGTLVSAAEGA 487
+ + + +EP E VI P A V + +
Sbjct: 10844 KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAI 10903
Query: 488 PGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEP 547
P ++ EK VP E V L K+ G E + P+E+V+ V+
Sbjct: 10904 PKKKV-PEKPQVP--EKVELTPLKV-----PGGEKKVRKLLPERKPEPKEEVVLKSVLRK 10955
Query: 548 ASNHEEEGENEITIGAEPKETTEDAAPPGPTS--ETPELATEQKPIQDPQPTP 598
EE + K + PP P E P + ++ I +P P
Sbjct: 10956 RPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVP 11008
Score = 45.8 bits (107), Expect = 1e-04
Identities = 77/371 (20%), Positives = 125/371 (33%), Gaps = 43/371 (11%)
Query: 264 PEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPP--VPPLPKVTPTKELQQENII 321
PE P+P+P +P ++ P P P Q ++ PP VP +PK
Sbjct: 10278 PEAPTPVPKKVEAPPAKVSKKIPEEKVP-VPVQKKEAPPAKVPEVPKK------------ 10324
Query: 322 SFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG--SAGVTHSPMSQT 379
VPE V P + VP K L + F+ EV V + + +
Sbjct: 10325 -------VPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEI 10377
Query: 380 LPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM--ICNLAESEQA-----PP 432
+ + + + F + + + + + + + E+E+ P
Sbjct: 10378 PEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPK 10437
Query: 433 TEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA 492
PK E + P + R E P + +P V V E P
Sbjct: 10438 APPKGPEISEKIIPPKKPPTKVVPRKEPPAK----VPEVPKKIVVEEKVRVPE-EPRVPP 10492
Query: 493 EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHE 552
+P E V E K+ + E+ P+ E V EK +P + P E
Sbjct: 10493 TKVPEVLPPKEVVP--EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVP---VPPPKKPE 10547
Query: 553 EEGEN--EITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLA 610
E+ A P++ +A PP P S PE+ K + + P+AP
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPV 10607
Query: 611 SAREASQELPP 621
EA +E+ P
Sbjct: 10608 KVPEAPKEVVP 10618
Score = 45.4 bits (106), Expect = 2e-04
Identities = 91/386 (23%), Positives = 138/386 (35%), Gaps = 50/386 (12%)
Query: 245 IQGAPSDSGPLRIA-KTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTR--KGP 301
I GA P + + P P+ SP P A+ SP+P R SPS R + P
Sbjct: 241 IDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR-HSPSPVRHVRAP 299
Query: 302 PVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP 361
P+ V+P + I S + + +T + PEV P+K
Sbjct: 300 TPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATG--PEVPP----------PWKQ 347
Query: 362 EVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMI 421
E A S+ + M +T TTST + G Q Q T S+
Sbjct: 348 EGYVASSS---EAEMRETT----LTTSTQIRTEERWEGRYG-VQEQVTISGAAGAAASVS 399
Query: 422 CNLAESEQAPPTEPK-----AEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAA 476
+ + + +A T K A++ A T +D+ R EPV AV A
Sbjct: 400 ASASYAAEAVATGAKEVKQDADKSAAVATVVAAVDMA---RVREPVISAV------EQTA 450
Query: 477 VGTLVSAAEGAPGEEA---EAEKATVP----AGEGVSLEEAKIGTETTEGAESAQPEAEE 529
T +A P +E EAEK V A + +E K T+ + Q
Sbjct: 451 QRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTH 510
Query: 530 LEATVPQEKV-IPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQ 588
+ EK +P VVI A E+E I + K+ T++A ET A
Sbjct: 511 EQIRKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAI----RQETEITAASM 566
Query: 589 KPIQDPQPTPSAPAMGAADQLASARE 614
+ + T GA ++ + ++
Sbjct: 567 VVVATAKSTKLETVPGAQEETTTQQD 592
Score = 42.7 bits (99), Expect = 0.001
Identities = 98/457 (21%), Positives = 147/457 (32%), Gaps = 87/457 (19%)
Query: 170 EEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYE 229
EEEF + ++ FEE EE L RV K H+ I V + E
Sbjct: 10380 EEEFHEVEEYFEEGEFHEVEEFIKLEQHRV--------EEEHRVEKVHRVIEVFEAEEVE 10431
Query: 230 VMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPA 289
V K AP GP I++ PP++P P P P P
Sbjct: 10432 VFEK------------PKAP-PKGP-EISEKIIPPKKPPTKVVPRKEP-PAKVPEVPKKI 10476
Query: 290 RPRSPSQTRKGPPVPP--LPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK 347
+ + P VPP +P+V P KE+ E + VP +VPE K
Sbjct: 10477 VVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP------VPPAKKPEAPPPKVPEAPK 10530
Query: 348 E---ETLLDLDFDPFKPEVTP-----AGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGS 399
E E + + P KPEV P A V + + +P
Sbjct: 10531 EVVPEKKVPVP-PPKKPEVPPTKVPEVPKAAVPEKKVPEAIP------------------ 10571
Query: 400 FNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAE 459
+P+ + + ++ ++ P PK E P ++ + +
Sbjct: 10572 ----PKPESPPPEVPEAPKEVV----PEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVP 10623
Query: 460 EPVEEAVIIPGADADAAVGTLV---SAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTET 516
P + +P V E P + E V+LEE E
Sbjct: 10624 VPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPP--AEV 10681
Query: 517 TEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTED----- 571
E E A P + TVP +K +P PA ++ + + PKE +
Sbjct: 10682 VEEPEPAAPP----QVTVPPKKPVPEKK-APAVVAKKPELPPVKVPEVPKEVVPEKKVPL 10736
Query: 572 ------AAPPGPTSETPELATEQKPIQDPQPTPSAPA 602
APP E P+ +K + P+ PA
Sbjct: 10737 VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPA 10773
Score = 42.4 bits (98), Expect = 0.001
Identities = 124/630 (19%), Positives = 215/630 (34%), Gaps = 102/630 (16%)
Query: 14 QKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEA 73
+K + + +E V +K + K E + + + E E E Y + +E
Sbjct: 9045 KKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEI 9104
Query: 74 SMKLTESLHEVYEPD------WYGREDVKMVGEK--------------CDVLWEDFHQKL 113
++ + +HE +E D +Y RE+ GE+ ++E+ H++
Sbjct: 9105 KVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERK 9164
Query: 114 VDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESR--ISKAEE 171
V + P I K + ++ S R E +Q +K + S+ + +
Sbjct: 9165 VPAKVPEKKA-----PPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPS 9219
Query: 172 EFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVM 231
++V E + + + ++ F +T + VS + KEI V K++ +
Sbjct: 9220 RTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEI-VTEEKIHVAI 9278
Query: 232 TKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARP 291
+K + + P P +A P P + P P P P P
Sbjct: 9279 SK----RVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE------VPKKPVPEEK 9328
Query: 292 RSPSQTRKGPPVPPLPKVTPTKELQQENI--------------ISFFEDNFVPEISVTTP 337
+ +K P PP P K + +E I + + V E +T
Sbjct: 9329 KPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIV 9388
Query: 338 SQNE------VPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDL 391
+Q E VPE+ K++ P + + P V P LP
Sbjct: 9389 TQREESPPPAVPEIPKKKV-------PEERKPVPRKEEEVPPPPKVPALP---------- 9431
Query: 392 VQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPK---AEEPLAAVTPAV 448
+P P++ + + AE + E K AEE L+ P
Sbjct: 9432 KKPV----------PEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVP-- 9479
Query: 449 GLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLE 508
TR E EE ++ + V V E E E E+A V E V E
Sbjct: 9480 --QRVEVTRHEVSAEEEWSY--SEEEEGVSISVYREE----EREEEEEAEVTEYE-VMEE 9530
Query: 509 EAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKET 568
+ E S + EAE E T QEK +V++P + E + PK+
Sbjct: 9531 PEEYVVEEKLHIISKRVEAEPAEVTERQEK---KIVLKPKIPAKIEEPPPAKVPEAPKKI 9587
Query: 569 TEDAAPPGPTSETPELATEQKPIQDPQPTP 598
+ P P + ++ + P + +P P
Sbjct: 9588 VPEKKVPAPVPKKEKVPPPKVPEEPKKPVP 9617
Score = 42.4 bits (98), Expect = 0.001
Identities = 57/246 (23%), Positives = 89/246 (36%), Gaps = 28/246 (11%)
Query: 425 AESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADA--AVGTLVS 482
A+ +APP PK E V P + + + E P + +P A +
Sbjct: 10515 AKKPEAPP--PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP 10572
Query: 483 AAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPS 542
E P E EA K VP E K+ + E + E V EK +P
Sbjct: 10573 KPESPPPEVPEAPKEVVP--------EKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVP- 10623
Query: 543 VVIEPASNHEEEGEN--EITIGAEPKETTEDAAPPGPTSETPEL--ATEQKPIQDP---- 594
+ P E E+ A P++ +A PP P S PE+ E+ +++P
Sbjct: 10624 --VPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEV 10681
Query: 595 --QPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVV 652
+P P+AP + + ++ P + K L + + + V LVV
Sbjct: 10682 VEEPEPAAPPQVT---VPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVV 10738
Query: 653 PSDSEA 658
P EA
Sbjct: 10739 PKKPEA 10744
Score = 42.0 bits (97), Expect = 0.002
Identities = 94/412 (22%), Positives = 153/412 (37%), Gaps = 47/412 (11%)
Query: 207 KNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPP-- 264
K + E F +E+ + Y V + H ++ F + P+++ + P P
Sbjct: 9901 KELEPEEVAFEEEVVTHVEE-YLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVP 9959
Query: 265 EEPSPLPSPTASPNHTLAPASPAPARPRSPSQT-------RKGPPVPPLPKVTPTKELQQ 317
EE P+P P AP + P P+ P + ++ PP +P+V P K + +
Sbjct: 9960 EEKKPVPVPKKKE----APPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV-PKKPVPE 10014
Query: 318 ENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMS 377
E + VP +VPEV K+ + + P+ A A V P
Sbjct: 10015 EKVP-------VPVPKKVEAPPAKVPEVPKKP-VPEKKVPVPAPKKVEAPPAKVPEVP-K 10065
Query: 378 QTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE--P 435
+ +P + T A +P + Q ++ + E E P E P
Sbjct: 10066 KLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLF----EEEIVPEEEVLP 10121
Query: 436 KAEEPLAAVTPAVGLDLGMDTRAEE-PVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEA 494
+ EE L + + + EE P EE + P + V E P + +
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181
Query: 495 E-KATVPAGEGVSLEEAKIGTETTEGAESAQPEA----EELEATVP-QEKVIPSVVIEPA 548
A VP + E+ + + E + PE EE +P +E+V+P +E
Sbjct: 10182 PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLP---VEVT 10238
Query: 549 SNHEEEGENEITIGAEPK--ETTEDAAPPGPTSETPELATEQKPIQDPQPTP 598
EEE +E I EP E E+ APP PE+ + P + P P P
Sbjct: 10239 EEPEEEPISEEEIPEEPPSIEEVEEVAPP----RVPEVIKKAVP-EAPTPVP 10285
Score = 35.8 bits (81), Expect = 0.14
Identities = 89/393 (22%), Positives = 137/393 (34%), Gaps = 60/393 (15%)
Query: 264 PEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISF 323
PEEP P P A P L A P P P + PP P +P+ P K +++ IS
Sbjct: 9799 PEEPVPT-KPKAPPAKVLKKAVPEEKVP-VPIPKKLKPPPPKVPE-EPKKVFEEKIRISI 9855
Query: 324 FE-----------------DNFVPEISVTTPSQNEVPEVKKEETLLDLDFDP--FKPEVT 364
+ V E V P + P V+ E +L+ + F+ EV
Sbjct: 9856 TKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVV 9915
Query: 365 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQ--PASGGSFNGFTQPQDTSLFTM-QTDQSMI 421
+ + + T ++V P P++ + + ++
Sbjct: 9916 THVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPP 9975
Query: 422 CNLAE-----SEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAA 476
+ E E+ P PK E+P A P V + + PV + V P A
Sbjct: 9976 AKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV 10035
Query: 477 VGTLVSAAE---GAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAES----------- 522
V + AP ++ EA A VP + E K T + E+
Sbjct: 10036 PKKPVPEKKVPVPAP-KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREP 10094
Query: 523 -----AQPEAEEL---EATVPQEKVIPSVVIEPASNHEEE---GENEITIGAEPKETTED 571
A P+ EE+ E VP+E+V+P E EEE E E+ E E+
Sbjct: 10095 VPVPVALPQEEEVLFEEEIVPEEEVLPEE--EEVLPEEEEVLPEEEEVLPEEEEIPPEEE 10152
Query: 572 AAPPGP--TSETPELATEQKPIQDPQPTPSAPA 602
PP E E E++ + + +P PA
Sbjct: 10153 EVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPA 10185
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/202 (22%), Positives = 78/202 (38%), Gaps = 20/202 (9%)
Query: 407 QDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPV-EEA 465
++ F T++ + + E ++ TE K A++ V + E+P EE
Sbjct: 9244 EEKMFFASHTEEEVSVTVPEVQKEIVTEEKIH---VAISKRVEPPPKVPELPEKPAPEEV 9300
Query: 466 VIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQP 525
+P V P + EK VP V +E + E + P
Sbjct: 9301 APVP---IPKKVEPPAPKVPEVPKKPVPEEKKPVP----VPKKEPAAPPKVPEVPKKPVP 9353
Query: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELA 585
E E++ V ++K P + P E +ITI + +E+ A P P + PE
Sbjct: 9354 E-EKIPVPVAKKKEAPPAKV-PEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPE-- 9409
Query: 586 TEQKPI----QDPQPTPSAPAM 603
E+KP+ ++ P P PA+
Sbjct: 9410 -ERKPVPRKEEEVPPPPKVPAL 9430
Score = 33.5 bits (75), Expect = 0.68
Identities = 35/126 (27%), Positives = 46/126 (36%), Gaps = 20/126 (15%)
Query: 259 KTPSPPEEPSPLPSPTAS-------------PNHTLAPASPAPARPRSPSQTRKGPP-VP 304
K P+ EEP P P A P P P P+ P +K PP V
Sbjct: 9567 KIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVI 9626
Query: 305 PLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKK----EETLLDLDFDPFK 360
+ + P K ++ I+ E V P + VPE K EE +L L P +
Sbjct: 9627 KMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKL--KPKR 9684
Query: 361 PEVTPA 366
E PA
Sbjct: 9685 EEEPPA 9690
Score = 33.5 bits (75), Expect = 0.68
Identities = 45/183 (24%), Positives = 59/183 (32%), Gaps = 19/183 (10%)
Query: 416 TDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADA 475
T + + ++APP EEP AV L L E P + +
Sbjct: 9644 TQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703
Query: 476 AVGTLVSAAEGAPGEEA----EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELE 531
V E P +E E E+A E VS++ + E E E E EE E
Sbjct: 9704 KVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREE---EYEEYEEYDYKEFEEYE 9760
Query: 532 ATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI 591
T E +EE E E E +E + P P PE KP
Sbjct: 9761 PT------------EEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPK 9808
Query: 592 QDP 594
P
Sbjct: 9809 APP 9811
Score = 33.5 bits (75), Expect = 0.68
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 7/64 (10%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPA-----RPRSPSQTRKGPPV 303
P P+ + P+ + +P PT P + PA P PA +P + +T K PPV
Sbjct: 10980 PPPPKPVEEVEVPTVTKRERKIPEPTKVPE--IKPAIPLPAPEPKPKPEAEVKTIKPPPV 11037
Query: 304 PPLP 307
P P
Sbjct: 11038 EPEP 11041
Score = 32.7 bits (73), Expect = 1.2
Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 12/121 (9%)
Query: 258 AKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPK--VTPTKEL 315
AK P P+E P A P P + P P+ P K P P+P+ +P E+
Sbjct: 10747 AKVPEVPKEVVP-EKKVAVPKKPEVPPAKVPEVPKKPVLEEK--PAVPVPERAESPPPEV 10803
Query: 316 QQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKP-EVTPAGSAGVTHS 374
+E + PE + + VP ++EE + P +P ++ P V
Sbjct: 10804 YEE------PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKK 10857
Query: 375 P 375
P
Sbjct: 10858 P 10858
Score = 32.3 bits (72), Expect = 1.5
Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 3/100 (3%)
Query: 505 VSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAE 564
+S E+ + T E PE ++ T + V S +EP E E
Sbjct: 9242 ISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVA 9301
Query: 565 PKETTEDAAPPGP-TSETPE--LATEQKPIQDPQPTPSAP 601
P + PP P E P+ + E+KP+ P+ P+AP
Sbjct: 9302 PVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Score = 32.3 bits (72), Expect = 1.5
Identities = 67/328 (20%), Positives = 114/328 (34%), Gaps = 45/328 (13%)
Query: 258 AKTPSPPEEPSPLPSPTASPNH--TLAPASPAPARPRSPSQTRKGPP------------- 302
A P P++ P+P P A P L P P + P
Sbjct: 10083 APPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLP 10142
Query: 303 ----VPPLPKVTPTKEL---QQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLD 355
+PP + P +E ++E + E+ +PE+ P VPE+KK+ T +
Sbjct: 10143 EEEEIPPEEEEVPPEEEYVPEEEEFVP--EEEVLPEVKPKVPVPAPVPEIKKKVTEKKVV 10200
Query: 356 FDPFKPEVTPAGSAGVTHSPMSQ--TLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P K E PA V + LP + ++ + +P++ +
Sbjct: 10201 I-PKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTE-----------EPEEEPISE 10248
Query: 414 MQTDQSMICNLAESEQAPPTEP---KAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPG 470
+ + E APP P K P A ++ +++ EE V +P
Sbjct: 10249 EEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPV 10308
Query: 471 ADADAAVGTLVSAAEGAPGEEA-EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEE 529
+A + + P ++ +K VP +G ++ E K+ + E E E
Sbjct: 10309 QKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQ--EVVVKERLE 10366
Query: 530 LEATVPQEKVIP-SVVIEPASNHEEEGE 556
LE + + IP + EEGE
Sbjct: 10367 LEVVEAEVEEIPEEEEFHEVEEYFEEGE 10394
Score = 32.0 bits (71), Expect = 2.0
Identities = 26/107 (24%), Positives = 36/107 (33%), Gaps = 4/107 (3%)
Query: 263 PPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIIS 322
P +P P P P + K P VP P P +E++ +
Sbjct: 10937 PERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTK 10996
Query: 323 ----FFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTP 365
E VPEI P P+ K E + + P +PE TP
Sbjct: 10997 RERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTP 11043
Score = 31.2 bits (69), Expect = 3.4
Identities = 35/117 (29%), Positives = 51/117 (43%), Gaps = 22/117 (18%)
Query: 202 YVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAK-- 259
Y +TF+ +SS++A +V+ V G Q A+ TIQ A R+ +
Sbjct: 32614 YKSTFE-ISSVQASDEGNYSVV------VENSEGKQEAEFTLTIQKA-------RVTEKA 32659
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQ 316
SPP SP P SP A +P R +SP + P K TPT+++Q
Sbjct: 32660 VTSPPRVKSPEPR-VKSPE-----AVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQ 32710
Score = 30.4 bits (67), Expect = 5.8
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 249 PSDSGPLRIAKTPSPPE-EPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLP 307
P + P + P PE P+ +P P PA P P R SP P P
Sbjct: 10753 PKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAP 10812
Query: 308 KVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVK 346
+ E ++ ++ E+ VP +V + +PE K
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKK 10851
Score = 30.4 bits (67), Expect = 5.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 11/86 (12%)
Query: 542 SVVIEPASNHEEEGENEITIGAEPKETTEDAAP-------PGPTSETPELATEQKPIQDP 594
SVV+E N E + E E T+ + TE A P P ++PE K ++ P
Sbjct: 32632 SVVVE---NSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSP 32688
Query: 595 QPTPSAPAMGAADQLASAREASQELP 620
+P+ A+ + + E Q LP
Sbjct: 32689 EPS-HPKAVSPTETKPTPTEKVQHLP 32713
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 56.2 bits (134), Expect = 1e-07
Identities = 92/380 (24%), Positives = 131/380 (34%), Gaps = 47/380 (12%)
Query: 249 PSDSG---PLRIAKTPSPPEEPSPLP--SPTASPNHTLAPASPAPARPRSPSQTRKGPPV 303
P+++G P KT S EP+ +P A+ N T +PA P R R+ ++ P
Sbjct: 498 PTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPA 557
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P T ++ S E E TP NE E E
Sbjct: 558 EPTENGDRTPLANEKTTPSLAEPT---ENGQRTPFANEKTTSSSAEPTEH-------EER 607
Query: 364 TPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICN 423
TP + T SP T + PA T + T+LF + ++
Sbjct: 608 TPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERT 667
Query: 424 LAE---SEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL 480
E S A PTE P A + + EP E P A+ + T
Sbjct: 668 ANEKTTSSPAEPTENGQRTPFANEKTT--------SSSAEPTEHGERTPLANEN----TT 715
Query: 481 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 540
+S AE E A + T P + + E T + AQP + EK
Sbjct: 716 LSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSP-AQPTENGDRTPLANEKTT 774
Query: 541 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 600
PS+ EP N + T A K TT +A P +E LA E T S+
Sbjct: 775 PSLA-EPTENGKR------TPFANEK-TTSSSAEPTEHAERTPLANEN--------TTSS 818
Query: 601 PAMGAADQLASAREASQELP 620
PA ++ +A E + + P
Sbjct: 819 PAEPTENRERTANEKTTQFP 838
Score = 54.3 bits (129), Expect = 4e-07
Identities = 92/374 (24%), Positives = 121/374 (32%), Gaps = 38/374 (10%)
Query: 254 PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPL------- 306
PL T P EP+ TA+ N T +PA P R + ++ PV P
Sbjct: 428 PLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTA 487
Query: 307 -PKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEET-LLDLDFDPFKPEVT 364
K TP+ EN P + T S + P E T L + + P E T
Sbjct: 488 NEKTTPSPAEPTEN------GQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPT 541
Query: 365 P----AGSAGVTHSPMSQT-----LPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQ 415
+ T SP T P T+ L +P G F + TS
Sbjct: 542 ENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 601
Query: 416 TDQSMICNLAESEQAP-PTEPKAEEPLAAVTPAVGLDLG-MDTRAEEPVEEAVIIPGADA 473
T+ LA P P EP A G + R E+ + P
Sbjct: 602 TEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPT 661
Query: 474 DAAVGTLVSAAEGAPGEEAEAEKATVPAGE---GVSLEEAKIGTET---TEGAESAQPEA 527
+ T +P E E + T A E S E + G T E + E
Sbjct: 662 ENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEP 721
Query: 528 EELEATVPQEKVIPSVVIEPASNHEE-EGENEITIGAEPKETTEDAAPPGPTSETPELAT 586
E EK P EP N E EN A+P E D P TP LA
Sbjct: 722 TENRERTANEKTTP-FPAEPTENRERTANENTTPSPAQPTE-NGDRTPLANEKTTPSLA- 778
Query: 587 EQKPIQDPQPTPSA 600
+P ++ + TP A
Sbjct: 779 --EPTENGKRTPFA 790
Score = 47.8 bits (112), Expect = 3e-05
Identities = 84/349 (24%), Positives = 119/349 (34%), Gaps = 56/349 (16%)
Query: 266 EPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFE 325
EP+ TA+ N+T +PA P R R+ ++ P P+ EN
Sbjct: 284 EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPI-----------ENRERTAN 332
Query: 326 DNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG----SAGVTHSPMSQTLP 381
+N P P++N + TL F E T G + T SP T
Sbjct: 333 ENTAP--FPAGPTENREMTANENTTL-------FPAEPTEHGERTANENTTPSPAEPTEH 383
Query: 382 WDLW---TTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAP----PTE 434
+ T+ +P G F + TS T+ LA P PTE
Sbjct: 384 GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTE 443
Query: 435 PKAEEPLAAVTPA-VGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAE 493
+ TP+ G +T A E + + P + + T +P E E
Sbjct: 444 NRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRET---TANEKTTPSPAEPTE 500
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
+ T A E +TT + SA+P + E PS EP N E
Sbjct: 501 NGQRTPFANE-----------KTT--SSSAEPTEHGERTPLANENTTPSPA-EPTENRER 546
Query: 554 EGENEITIGAEPKETTE--DAAPPGPTSETPELATEQKPIQDPQPTPSA 600
+ T P E TE D P TP LA +P ++ Q TP A
Sbjct: 547 TANEKTT--PSPAEPTENGDRTPLANEKTTPSLA---EPTENGQRTPFA 590
Score = 47.4 bits (111), Expect = 5e-05
Identities = 91/386 (23%), Positives = 125/386 (32%), Gaps = 70/386 (18%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQEN 319
TPSP E P+ TA+ N TL+PA P R R+ ++ P P T +E+
Sbjct: 298 TPSPAE-PTENRERTANENTTLSPAEPIENRERTANENTAPFPAGP----TENREMTANE 352
Query: 320 IISFF------------EDNFVPEISV------------TTPSQNEVPE------VKKEE 349
+ F +N P + TTPS E E ++
Sbjct: 353 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 412
Query: 350 TLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDT 409
T E TP + T SP T + PA T + T
Sbjct: 413 TTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKT 472
Query: 410 SLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIP 469
+L ++ ++ E P EP TP + + + EP E P
Sbjct: 473 TLSPVEPTENRETTANEKTTPSPAEPTEN---GQRTPFA--NEKTTSSSAEPTEHGERTP 527
Query: 470 GADADAAVGTLVSAAEGAPGEEAEAEKATVPA-------GEGVSLEEAKIGTETTEGAES 522
A+ + T S AE E A + T P+ G+ L K E E+
Sbjct: 528 LANEN----TTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTEN 583
Query: 523 AQPEAEELEATVPQEKVIPSVVIEPASNHEEE----GENEITIGAEPKETTEDAA----- 573
Q E T S EP + HEE EN AEP E E A
Sbjct: 584 GQRTPFANEKTT-------SSSAEP-TEHEERTPLANENTTPSPAEPTENRERTANENTT 635
Query: 574 --PPGPTSETPELATEQKPIQDPQPT 597
P GPT A E+ + +PT
Sbjct: 636 PSPAGPTENREMTANEKTTLFPAEPT 661
Score = 47.4 bits (111), Expect = 5e-05
Identities = 89/381 (23%), Positives = 127/381 (33%), Gaps = 49/381 (12%)
Query: 254 PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTK 313
PL T S P EP+ TA+ T PA P R + ++ K P P P
Sbjct: 809 PLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANE--KTTPFPAEPTENREW 866
Query: 314 ELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTH 373
+ +S E E TP NE + E + + PF E T SA T
Sbjct: 867 TANENTTLSPAEPT---EHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTE 923
Query: 374 SPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPT 433
L ++ T S +P G + + + ++ + A PT
Sbjct: 924 HGERTPLANEITTPSR--AEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPT 981
Query: 434 EPKAEEPLA----AVTPAVGLDLGMDTRAE-------EPVEEAVIIPGADADAAVGTLVS 482
E PLA +P + G T E EP E P A+ T+ S
Sbjct: 982 ENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEK----TIPS 1037
Query: 483 AAEGAPGEE--AEAEKATVPA-------GEGVSLEEAKI----------GTETTEGAES- 522
A+ EE A + T P+ GE +L KI G +TT E
Sbjct: 1038 PAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKI 1097
Query: 523 ----AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPT 578
A+P T P +K+ S ++ H + + I P E + A
Sbjct: 1098 TPSLAKPTEHGERTTSPNDKITSSAA--ESTEHRDRATSANVITPAPAEPIKHAKRTTLA 1155
Query: 579 SETPELATEQKPIQDPQPTPS 599
E TE K + P+ T S
Sbjct: 1156 HEKMTQVTE-KSTEHPEKTTS 1175
Score = 32.0 bits (71), Expect = 2.0
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 17/106 (16%)
Query: 249 PSDSG---PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPP 305
P+++G PL T + P E + TA+ T +PA P R+PS K P
Sbjct: 980 PTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIP--- 1036
Query: 306 LPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETL 351
+P K + E + +N TTPS + E ++ TL
Sbjct: 1037 ----SPAKPTEHEEMTPSANEN-------TTPSPVKPTEHGEKTTL 1071
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 55.1 bits (131), Expect = 2e-07
Identities = 51/209 (24%), Positives = 83/209 (39%), Gaps = 15/209 (7%)
Query: 12 NVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQ 71
++ K+ NR + G A + KDE FEE +NF+ QE R+L YL I+ +
Sbjct: 996 SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIR--E 1053
Query: 72 EASMKLTESLHEVYEPDWYGREDVKMVGEK----CDVLWEDFHQKLVDGSLLTLDTYLGQ 127
A +K+ ++ G D++ D L+ +F ++ + L+ L
Sbjct: 1054 SACVKVVAAVSMWDVCMERGHRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSM 1113
Query: 128 FPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDL 187
F + KR KL+D+ + E L+ K EE Q A+ +E N L
Sbjct: 1114 FTGPHKLVQKRFDKLLDFYNCTERAEKLKD---------KKTLEELQSARNNYEALNAQL 1164
Query: 188 QEELPSLWSRRVGFYVNTFKNVSSLEAKF 216
+ELP G + N + F
Sbjct: 1165 LDELPKFHQYAQGLFTNCVHGYAEAHCDF 1193
Score = 30.8 bits (68), Expect = 4.4
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 14/63 (22%)
Query: 632 DFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFT 691
+F + D L L RGD+V+ L G+ + WLQ R +G FP +
Sbjct: 76 EFTSQELDNLPLHRGDLVI--------------LDGIPTAGWLQGRSCWGARGFFPSSCV 121
Query: 692 RRL 694
R L
Sbjct: 122 REL 124
Score = 29.6 bits (65), Expect = 9.8
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 15/83 (18%)
Query: 612 AREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKES 671
++ A ++P + + L A +EL + GDV+ + +GV E
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITI--------------IGVPEP 180
Query: 672 DWLQYRDLATYKGLFPENFTRRL 694
W + +L +G+FPE F L
Sbjct: 181 GWFE-GELEGRRGIFPEGFVELL 202
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 55.1 bits (131), Expect = 2e-07
Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 23/238 (9%)
Query: 402 GFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAE-- 459
G QP+ + + + M AE E P ++ +P + A ++ G + E
Sbjct: 1991 GEAQPESEDVEAPEAEGEM--QEAEEEAQPESDGVEAQPKSEGEEAQEVE-GETQKTEGD 2047
Query: 460 -EPVEEAVIIPGADADA--AVGTLVSAAEGAPGEEAE------AEKATVPAGEGVSLEEA 510
+P + V P A+ +A A G V AEG E+E AE P EGV EA
Sbjct: 2048 AQPESDGVEAPEAEEEAQEAEGE-VQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEA 2106
Query: 511 KIGTETTEGAES------AQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAE 564
+ + EG E+ AQPE+E +EA + + P A + E E + E + G E
Sbjct: 2107 EGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPE-SEGIE 2165
Query: 565 PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAAD-QLASAREASQELPP 621
+E E+A P E PE E +P + P A + + A EA +E P
Sbjct: 2166 AQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQP 2223
Score = 53.9 bits (128), Expect = 5e-07
Identities = 57/208 (27%), Positives = 83/208 (39%), Gaps = 36/208 (17%)
Query: 425 AESEQAPPTEP-KAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSA 483
AE E P +E +A E A G++ +P E + P A+ +A
Sbjct: 2090 AEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQ-----PE 2144
Query: 484 AEGAPGEEAEAEKATVPAGEGVSLEEAKI-------GTETTEGAESAQPEAEELEATVPQ 536
+EG ++AE E P EG+ +EA+ G E E AQPE+E +EA
Sbjct: 2145 SEGVEAQDAEGEAQ--PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEA---- 2198
Query: 537 EKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQ- 595
P + E + E E G E E E+A P ETPE E +P + +
Sbjct: 2199 ----------PEAEGEAQPELE---GVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGET 2245
Query: 596 --PTPSAPAMGAAD-QLASAREASQELP 620
+P + D Q A E+S +P
Sbjct: 2246 QGEKKGSPQVSLGDGQSEEASESSSPVP 2273
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/216 (25%), Positives = 82/216 (37%), Gaps = 31/216 (14%)
Query: 425 AESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAE-EPVEEAVIIPGADADAAVGTLVSA 483
AE +AP E +A+ V + E +P E V P A+ +A
Sbjct: 1832 AEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQ------- 1884
Query: 484 AEGAPGEEAEAEKATVPAGEGVSL----EEAKIGTETTEGAESA---QPEAEELEA---- 532
E E EAE P EG +EA+ TE+ E E+ +PE+E EA
Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944
Query: 533 ---------TVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPE 583
T P+ +VI S E + E E + + E +E +A P E PE
Sbjct: 1945 EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPE 2004
Query: 584 LATEQKPIQDPQPTPSAPAMGAADQLASAREASQEL 619
E +Q+ + + G Q S E +QE+
Sbjct: 2005 AEGE---MQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/187 (26%), Positives = 74/187 (39%), Gaps = 32/187 (17%)
Query: 455 DTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEG-----VSLEE 509
+T+ EE ++E G + T + EG EEA+ E+ GEG V LEE
Sbjct: 1324 ETKTEEGLQEE----GVQLEE---TKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEE 1376
Query: 510 AKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENE----------- 558
K G E G + E E +P+E + + AS+ + +G E
Sbjct: 1377 VKEGPEG--GLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGR 1434
Query: 559 ITIGAEP---KETTEDAAPPGPTSETPELATEQKPIQDPQP----TPSAPAMGAADQLAS 611
+ AEP + T E PP SET A+E++ +P P A MG A
Sbjct: 1435 ASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQ 1494
Query: 612 AREASQE 618
+ + E
Sbjct: 1495 PTQGAAE 1501
Score = 41.6 bits (96), Expect = 0.003
Identities = 58/235 (24%), Positives = 84/235 (35%), Gaps = 42/235 (17%)
Query: 392 VQPASGGS----FNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE-PKAEEPLAAVTP 446
VQP S G+ QP+ S+ ++T E E P +E +A+E A
Sbjct: 1899 VQPESEGAEAPEAEKEAQPETESVEALET---------EGEDEPESEGAEAQEAEEAAQE 1949
Query: 447 AVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVS 506
A G E E P ++ A+ V E + E+E P EG
Sbjct: 1950 AEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEG-- 2007
Query: 507 LEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPK 566
E E E AQPE++ +EA +P S EGE + E +
Sbjct: 2008 --------EMQEAEEEAQPESDGVEA-------------QPKS----EGEEAQEVEGETQ 2042
Query: 567 ETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPP 621
+T DA P E PE E + + A ++ + A+EA E P
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-DAQEAEGEAQP 2096
Score = 36.6 bits (83), Expect = 0.081
Identities = 40/184 (21%), Positives = 61/184 (33%), Gaps = 32/184 (17%)
Query: 460 EPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEG 519
E +E G +A EG E + E+ GEG EEA++ G
Sbjct: 1304 EETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETG 1363
Query: 520 AESAQPEAEELEAT---------------------VPQEKVIPSVVIEPASNHEEEGENE 558
E Q E +LE +P+E + + AS+ + +G E
Sbjct: 1364 GEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQE 1423
Query: 559 ITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQE 618
+P + E P TE +PT + D AS R++ +
Sbjct: 1424 ----DDPVQEEEAGRASASAEPCPAEGTE-------EPTEPPSHLSETDPSASERQSGSQ 1472
Query: 619 LPPG 622
L PG
Sbjct: 1473 LEPG 1476
Score = 35.4 bits (80), Expect = 0.18
Identities = 54/225 (24%), Positives = 79/225 (35%), Gaps = 42/225 (18%)
Query: 387 TSTDLVQPASGGSFNGFTQPQ-----DTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPL 441
TST VQ A GG G +Q + + + ++ L E+E + + +
Sbjct: 1718 TSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTH 1777
Query: 442 AAVTPAVGLDLGMDTRAEEPVEEAVIIPGADA---DAAVGTLVSAAEGAPGEEAEAEKAT 498
+ T A G +LG + E + E G + D G + + PG+ AE
Sbjct: 1778 NSETSA-GSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIE 1836
Query: 499 VPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENE 558
P EG AQPE+E +EA A +E E E
Sbjct: 1837 APEAEG-----------------EAQPESEGVEA-------------PEAEGDAQEAEGE 1866
Query: 559 ITIGAEPKETTE---DAAPPGPTSETPELATEQKPIQDPQPTPSA 600
+E E E +A P ETPE E +P + P A
Sbjct: 1867 AQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEA 1911
Score = 32.0 bits (71), Expect = 2.0
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 14/112 (12%)
Query: 202 YVNTFKNVSSLEAKFHKEIAVLC--HKLYEVMTKLGDQHADKAFTIQGAPSDS-----GP 254
Y + K V SL+A H ++C H+ + + + +A T+ G S + GP
Sbjct: 197 YTTSGKKVDSLQALLHSPSVLVCAGHEAFRTPA-MKNARRSEAETLSGLTSRNKNGSWGP 255
Query: 255 LR---IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPV 303
+ + SPP LP P + P PAP R + + GP V
Sbjct: 256 KTKPSVIHSRSPPGSTPRLPE---RPGPSNPPVGPAPGRHPQDTPAQSGPLV 304
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 53.5 bits (127), Expect = 6e-07
Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 17/150 (11%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPP- 302
T+ + S P TP P PSP + T SP T P P SP T PP
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPT 1693
Query: 303 ---VPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPE--------VKKEETL 351
P P TP+ + S P ++TTPS P + T
Sbjct: 1694 TTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS 1753
Query: 352 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLP 381
L P P +TP T SP S T P
Sbjct: 1754 SPLTTTPLPPSITPP-----TFSPFSTTTP 1778
Score = 50.4 bits (119), Expect = 5e-06
Identities = 74/348 (21%), Positives = 99/348 (28%), Gaps = 43/348 (12%)
Query: 260 TPSPPEE-PSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVP----PLPKVTPTKE 314
TPSPP PSP P+ T + T P+ P P T PP+ P P TP+
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP- 1456
Query: 315 LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
P + TTP P P P TP+ T +
Sbjct: 1457 ---------------PISTTTTPPPTTTPSPPTTT--------PSPPTTTPSPPTTTTTT 1493
Query: 375 PMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTE 434
P T P T+T + PAS + T P + T + + +PPT
Sbjct: 1494 PPPTTTPSP--PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT-------TTPSPPTT 1544
Query: 435 PKAEEPLAAVT-PAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAE 493
P + T P T P P + T+ + P
Sbjct: 1545 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP-PPTTTPS 1603
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
T + T T + + P P P+
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1663
Query: 554 EGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAP 601
IT P TT P P + TP T P TPS+P
Sbjct: 1664 TPSPPITTTTTPPPTT---TPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708
Score = 45.1 bits (105), Expect = 2e-04
Identities = 68/335 (20%), Positives = 89/335 (26%), Gaps = 52/335 (15%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPP---VPPLPKVTPTKELQ 316
TPSPP + P PT +P+ SP P P+ T PP P P TP
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512
Query: 317 QENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLL-DLDFDPFKPEVTPAGSAGVTHSP 375
+ P + TTP P + P TP+ T +P
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572
Query: 376 MSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEP 435
T P TT+ S + T P T+ T + PPT
Sbjct: 1573 PPTTTPSPPTTTT------PSPPTITTTTPPPTTTPSPPTT---------TTTTPPPTTT 1617
Query: 436 KAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAE 495
+ +TP T P P P +
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP------------------PPTTTPSP 1659
Query: 496 KATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEG 555
T ++ T T + P T P PS
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS------------- 1706
Query: 556 ENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
+ IT P TT + PP T TP T P
Sbjct: 1707 -SPITTTTTPSSTTTPSPPP-TTMTTPSPTTTPSP 1739
Score = 42.4 bits (98), Expect = 0.001
Identities = 83/407 (20%), Positives = 122/407 (29%), Gaps = 61/407 (14%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQ 296
T+ P+ +G P+ T +P P+ +PT +P T +P P + +Q
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQ 3964
Query: 297 TRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLDLD 355
T P+ VTPT + ++ T TP+ + P T +
Sbjct: 3965 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4024
Query: 356 FDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQ 415
P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 4025 -----PTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071
Query: 416 TDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADA 475
T Q P T P TP G T P+ +
Sbjct: 4072 TPTPT------GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPT 4122
Query: 476 AVGTLVSAAEGAPGEEAEAEKATV---PAGEGVSLEEAKIGTETTEGAESAQPEAEELEA 532
T P TV P G T TT + P +
Sbjct: 4123 GTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174
Query: 533 TVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPP------------GPTSE 580
T P +V P + G T A E T PP P +E
Sbjct: 4175 TTPITTTT-TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233
Query: 581 TPELATEQKPIQD-----PQPTPSAPAMGAADQLASAREASQELPPG 622
+ L + P + P TP+AP + S ++ PPG
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 4280
Score = 38.1 bits (87), Expect = 0.028
Identities = 79/384 (20%), Positives = 115/384 (29%), Gaps = 58/384 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3953 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 4013 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 4069 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 4115
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADA 473
T Q P T P TP G T P+
Sbjct: 4116 TPTP------TPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPI----------- 4155
Query: 474 DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGA---ESAQPEAEEL 530
T + P T P ++ T T G S P AE
Sbjct: 4156 -----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT 4210
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELA--TEQ 588
+ P E P S+ E ++ E T A P PT+ T T
Sbjct: 4211 TSNPPPESSTPQ-TSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269
Query: 589 KPIQDPQPTPSAPAMGAADQLASA 612
P P P G +SA
Sbjct: 4270 PPPSTTTSPPGTPTRGTTTGSSSA 4293
Score = 36.2 bits (82), Expect = 0.11
Identities = 44/199 (22%), Positives = 67/199 (33%), Gaps = 22/199 (11%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPK 308
P + P+ T +P P+ +PT +P T +P P + +QT P+
Sbjct: 1895 PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTT 1952
Query: 309 VTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG 367
VTPT + ++ T TP+ + P T + P TP G
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTG 2007
Query: 368 SAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAES 427
+ T +P++ TT+T P G+ T P T+ T
Sbjct: 2008 TQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTG 2053
Query: 428 EQAPPTEPKAEEPLAAVTP 446
Q P T P TP
Sbjct: 2054 TQTPTTTPITTTTTVTPTP 2072
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 1998 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2057
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2058 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2113
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2114 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2160
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2161 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2187
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2172
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2173 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2228
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2229 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2275
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2276 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2302
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2228 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2287
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2288 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2344 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2390
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2391 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2417
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2403 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2459 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2505
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2506 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2532
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2458 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2517
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2518 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2573
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2574 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2620
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2621 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2647
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2573 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2633 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2689 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2735
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2736 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2762
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2748 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2803
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2804 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2850
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2851 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2877
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2803 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2863 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2918
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 2919 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 2966 TPTP------TPTGTQTPTTTPITTTTTVTPTP 2992
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 2918 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 2978 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3034 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3080
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3081 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3107
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3033 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3092
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3093 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3148
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3149 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3195
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3196 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3222
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3148 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3208 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3263
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3264 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3310
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3311 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3337
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3263 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3322
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3323 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3379 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3425
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3426 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3452
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3378 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3437
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3438 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3493
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3494 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3540
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3541 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3567
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3553 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3608
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3609 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3655
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3656 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3682
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3608 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3667
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3668 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3724 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3770
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3771 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3797
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3783 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3838
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3839 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 3885
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 3886 TPTP------TPTGTQTPTTTPITTTTTVTPTP 3912
Score = 33.5 bits (75), Expect = 0.68
Identities = 46/213 (21%), Positives = 72/213 (33%), Gaps = 33/213 (15%)
Query: 244 TIQGAPSDSG-------PLRIAKTPSPPEEPSPLPSPTASP--NHTLAPASPAPARPRSP 294
T+ P+ +G P+ T +P P+ +PT +P T +P P ++P
Sbjct: 3838 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3897
Query: 295 SQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVT-TPSQNEVPEVKKEETLLD 353
+ T P+ VTPT + ++ T TP+ + P T
Sbjct: 3898 TTT----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3953
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
+ P TP G+ T +P++ TT+T P G+ T P T+
Sbjct: 3954 V-----TPTPTPTGTQTPTTTPIT--------TTTTVTPTPTPTGTQTPTTTPITTTTTV 4000
Query: 414 MQTDQSMICNLAESEQAPPTEPKAEEPLAAVTP 446
T Q P T P TP
Sbjct: 4001 TPTP------TPTGTQTPTTTPITTTTTVTPTP 4027
Score = 32.7 bits (73), Expect = 1.2
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 16/88 (18%)
Query: 262 SPPEEPSPLPSPTASPNHTLAPASPAPARPRS-PSQTRKGPPVPPLPKVTPTKELQQENI 320
S P PSP P+P+ S +P P++P S PS+ G P P P + QEN
Sbjct: 4375 SCPSTPSPTPTPSKS--------TPTPSKPSSTPSKPTPGTKPPECPDFDPPR---QENE 4423
Query: 321 ISFFEDNFVPEISVTTPSQNEVPEVKKE 348
+ D F+ T N V VK E
Sbjct: 4424 TWWLCDCFM----ATCKYNNTVEIVKVE 4447
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 53.5 bits (127), Expect = 6e-07
Identities = 91/380 (23%), Positives = 130/380 (34%), Gaps = 47/380 (12%)
Query: 249 PSDSG---PLRIAKTPSPPEEPSPLP--SPTASPNHTLAPASPAPARPRSPSQTRKGPPV 303
P+++G P KT S EP+ +P A+ N T +PA P R R+ ++ P
Sbjct: 560 PTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPA 619
Query: 304 PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
P T ++ S E E TP NE E E
Sbjct: 620 EPTENGDRTPLANEKTTPSLAEPT---ENGQRTPFANEKTTSSSAEPTEH-------EER 669
Query: 364 TPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICN 423
TP + T SP T + PA T + T+LF + ++
Sbjct: 670 TPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERT 729
Query: 424 LAE---SEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL 480
E S A PTE P A + + EP E P A+ + T
Sbjct: 730 ANEKTTSSPAEPTENGQRTPFANEKTT--------SSSAEPTEHGERTPLANEN----TT 777
Query: 481 VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI 540
+S A E A + T P + + E T + AQP + EK
Sbjct: 778 LSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSP-AQPTENGDRTPLANEKTT 836
Query: 541 PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA 600
PS+ EP N + T A K TT +A P +E LA E T S+
Sbjct: 837 PSLA-EPTENGKR------TPFANEK-TTSSSAEPTEHAERTPLANEN--------TTSS 880
Query: 601 PAMGAADQLASAREASQELP 620
PA ++ +A E + + P
Sbjct: 881 PAEPTENRERTANEKTTQFP 900
Score = 52.4 bits (124), Expect = 1e-06
Identities = 91/377 (24%), Positives = 123/377 (32%), Gaps = 44/377 (11%)
Query: 254 PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPL------- 306
PL T P EP+ TA+ N T +PA P R + ++ PV P
Sbjct: 490 PLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTA 549
Query: 307 -PKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEET-LLDLDFDPFKPEVT 364
K TP+ EN P + T S + P E T L + + P E T
Sbjct: 550 NEKTTPSPAEPTEN------GQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPT 603
Query: 365 P----AGSAGVTHSPMSQT-----LPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQ 415
+ T SP T P T+ L +P G F + TS
Sbjct: 604 ENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP 663
Query: 416 TDQSMICNLAESEQAP-PTEPKAEEPLAAVTPAVGLDLG-MDTRAEEPVEEAVIIPGADA 473
T+ LA P P EP A G + R E+ + P
Sbjct: 664 TEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPT 723
Query: 474 DAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAK---------IGTETTEGAESAQ 524
+ T +P E E + T A E + A+ + E T + +
Sbjct: 724 ENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGP 783
Query: 525 PEAEELEATVPQEKVIPSVVIEPASNHEE-EGENEITIGAEPKETTEDAAPPGPTSETPE 583
E E A EK P EP N E EN A+P E D P TP
Sbjct: 784 TENRERTA---NEKTTP-FPAEPTENRERTANENTTPSPAQPTE-NGDRTPLANEKTTPS 838
Query: 584 LATEQKPIQDPQPTPSA 600
LA +P ++ + TP A
Sbjct: 839 LA---EPTENGKRTPFA 852
Score = 47.8 bits (112), Expect = 3e-05
Identities = 91/386 (23%), Positives = 125/386 (32%), Gaps = 70/386 (18%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQEN 319
TPSP E P+ TA+ N TL+PA P R R+ ++ P P T +E+
Sbjct: 360 TPSPAE-PTENRERTANENTTLSPAEPTENRERTANENTAPFPAGP----TENREMTANE 414
Query: 320 IISFF------------EDNFVPEISV------------TTPSQNEVPE------VKKEE 349
+ F +N P + TTPS E E ++
Sbjct: 415 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 474
Query: 350 TLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDT 409
T E TP + T SP T + PA T + T
Sbjct: 475 TTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKT 534
Query: 410 SLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIP 469
+L ++ ++ E P EP TP + + + EP E P
Sbjct: 535 TLSPVEPTENRETTANEKTTPSPAEPTEN---GQRTPFA--NEKTTSSSAEPTEHGERTP 589
Query: 470 GADADAAVGTLVSAAEGAPGEEAEAEKATVPA-------GEGVSLEEAKIGTETTEGAES 522
A+ + T S AE E A + T P+ G+ L K E E+
Sbjct: 590 LANEN----TTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTEN 645
Query: 523 AQPEAEELEATVPQEKVIPSVVIEPASNHEEE----GENEITIGAEPKETTEDAA----- 573
Q E T S EP + HEE EN AEP E E A
Sbjct: 646 GQRTPFANEKTT-------SSSAEP-TEHEERTPLANENTTPSPAEPTENRERTANENTT 697
Query: 574 --PPGPTSETPELATEQKPIQDPQPT 597
P GPT A E+ + +PT
Sbjct: 698 PSPAGPTENREMTANEKTTLFPAEPT 723
Score = 46.6 bits (109), Expect = 8e-05
Identities = 84/349 (24%), Positives = 118/349 (33%), Gaps = 56/349 (16%)
Query: 266 EPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFE 325
EP+ TA+ N+T +PA P R R+ ++ P P EN
Sbjct: 346 EPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEP-----------TENRERTAN 394
Query: 326 DNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG----SAGVTHSPMSQTLP 381
+N P P++N + TL F E T G + T SP T
Sbjct: 395 ENTAP--FPAGPTENREMTANENTTL-------FPAEPTEHGERTANENTTPSPAEPTEH 445
Query: 382 WDLW---TTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAP----PTE 434
+ T+ +P G F + TS T+ LA P PTE
Sbjct: 446 GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTE 505
Query: 435 PKAEEPLAAVTPA-VGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAE 493
+ TP+ G +T A E + + P + + T +P E E
Sbjct: 506 NRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRET---TANEKTTPSPAEPTE 562
Query: 494 AEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEE 553
+ T A E +TT + SA+P + E PS EP N E
Sbjct: 563 NGQRTPFANE-----------KTT--SSSAEPTEHGERTPLANENTTPSPA-EPTENRER 608
Query: 554 EGENEITIGAEPKETTE--DAAPPGPTSETPELATEQKPIQDPQPTPSA 600
+ T P E TE D P TP LA +P ++ Q TP A
Sbjct: 609 TANEKTT--PSPAEPTENGDRTPLANEKTTPSLA---EPTENGQRTPFA 652
Score = 34.3 bits (77), Expect = 0.40
Identities = 67/348 (19%), Positives = 117/348 (33%), Gaps = 24/348 (6%)
Query: 259 KTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQE 318
KT P EP+ TA+ T PA P R + ++ P P T + E
Sbjct: 895 KTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDE 954
Query: 319 NIISFFEDNFVPE----ISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHS 374
N+ + F E I T S E + + A S +
Sbjct: 955 NLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEIT 1014
Query: 375 PMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM--ICNLAESEQAPP 432
S +P + +T+ + ++ ++ S +P S+ +++ + + N S
Sbjct: 1015 MSSAAIP--VSSTAYETIRFSTAVS-----EPVTASILALESTLAFTTVSNTTTSSTVTS 1067
Query: 433 TEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEA 492
A + T A + T A I D + T V AAE P
Sbjct: 1068 VPTTASTSGSKNTTACEATMSETT-------IAAITASEDTTVSTQTSVIAAESVPHTAT 1120
Query: 493 EAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHE 552
+ T A ++ + + T +A A + T + ++ P +
Sbjct: 1121 KTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFT 1180
Query: 553 EEGENEITIGAE-PKETTEDAAPPGPTSETPELATEQKPIQDPQPTPS 599
++IT G+E P +T D+A +++ E P P PTP+
Sbjct: 1181 T--TSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAP-PTPA 1225
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 52.4 bits (124), Expect = 1e-06
Identities = 76/332 (22%), Positives = 132/332 (39%), Gaps = 42/332 (12%)
Query: 12 NVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQ 71
++Q+RLN+ Q + LQK ++ ++EQ E +Q +++ E + L+ ELR A ++
Sbjct: 105 SLQQRLNQFQHE-LQK----NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHL 159
Query: 72 EASMKLTESLHE---VYEPDWYGREDVKMVGEKCDVLWEDFHQ-KLVDGSLLTLDTYLGQ 127
L + L + + + + C L D H L GS L+ + G
Sbjct: 160 RQICGLEQQLRQQQGLQDAAFSNLSPPPAPAPPCTDL--DLHYLALRGGSGLSHAGWPGS 217
Query: 128 FPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDL 187
P + + +R + ++ +A+ Q + + ++ + + E ++ Q+ +
Sbjct: 218 TPSVSDLERRRLEEALE--AAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASN 275
Query: 188 QEELPSLWSRRVG--------FYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHA 239
Q E W +RVG Y + + L + +L L E G +H+
Sbjct: 276 QSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHS 335
Query: 240 DKAFTIQGAP---SDSGPLRIAKTPSP-----PEEPSPLPSPTASPNHTLAPASPA---- 287
+ AP S S P R A P P+ SP+P P SP +PASP+
Sbjct: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVP-PCPSPQQRRSPASPSCPSP 394
Query: 288 --------PARPRSPSQTRKGPPVPPLPKVTP 311
P +SPS R+ P P P P
Sbjct: 395 VPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQP 426
>gi|8923904 bridging integrator 3 [Homo sapiens]
Length = 253
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/220 (20%), Positives = 104/220 (47%), Gaps = 17/220 (7%)
Query: 33 ETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGR 92
+T + FE ++ E + RLQ++++ A M ++++K+ SL + P
Sbjct: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI--SLDLLSNPLCEQD 75
Query: 93 EDVKMVGEKCDVL---WEDFHQKLVDGSLLT----LDTYLGQFPDIKNRIAKRSRKLVDY 145
+D+ + D + F+Q+ V+ T L + FP + + +R + L DY
Sbjct: 76 QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY 135
Query: 146 DSARHHLEALQSSKRKDE--SRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYV 203
+ +E + ++ +++ +A EE + ++ FE N L EE+P + R+ ++
Sbjct: 136 RRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQ 195
Query: 204 NTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQ--HADK 241
+F+++ + ++ E+ HK++ ++ DQ H+D+
Sbjct: 196 PSFESLIRAQVVYYSEM----HKIFGDLSHQLDQPGHSDE 231
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 51.2 bits (121), Expect = 3e-06
Identities = 86/379 (22%), Positives = 128/379 (33%), Gaps = 66/379 (17%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPL-P 307
PS G + P P+ PS P T PA P SP P V PL P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP-SPKGDPTSPAVIPLSP 1412
Query: 308 KVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEV---KKEETLLDLDFDPFKPEVT 364
K P + +E + + + P +VT S + P K DP P VT
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPP-AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 365 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNL 424
P SP P + T+S+ PA+ T P
Sbjct: 1472 PP-------SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP-------------- 1510
Query: 425 AESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGT-LVSA 483
+ ++ P T +P+A P L L T A +EA+I P + T +
Sbjct: 1511 SSPKEVPATPSSRRDPIA---PTATL-LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
Query: 484 AEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSV 543
+ AP + E ++ PA + T +GA S P+E +IP
Sbjct: 1567 PKEAPATPSSKEASSPPA----------VTPSTYKGAPS------------PKELLIPPA 1604
Query: 544 VIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPI--QDPQPTPSAP 601
V P+ P T + GP + P+ P+ + +P++P
Sbjct: 1605 VTSPSPKE----------APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654
Query: 602 AMGAADQLASAREASQELP 620
A A+ +AS+ LP
Sbjct: 1655 ASVTCKMGATVPQASKGLP 1673
Score = 50.1 bits (118), Expect = 7e-06
Identities = 100/388 (25%), Positives = 126/388 (32%), Gaps = 56/388 (14%)
Query: 231 MTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPA--P 288
MT + A +G P+ P + A TP PSP P A+P+ AP PA P
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPKGGP-ATPSPKWAPTPPAATP 970
Query: 289 ARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEV---PEV 345
P KG P P PK PT P+ TPS P V
Sbjct: 971 PSP-------KGGPATPSPKGAPTPPAATPP---------SPKGGPATPSPKGAPTPPAV 1014
Query: 346 KKEETLLDLDFDPF------KPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGS 399
PF P TP G SP + LP TT + GG
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKG---SPAATPLPKGAPTTPAATLPSPKGG- 1070
Query: 400 FNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAE 459
P SL T + + A P+ A P AA P+ L A
Sbjct: 1071 ------PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL-----AT 1119
Query: 460 EPVEEAVIIPGADADAAVGTLVS-AAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTE 518
P + A P A + G L + +GAP A AT P+ +G G TT
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA----ATPPSPKGGLATPPPKGAPTTP 1175
Query: 519 GAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPT 578
A P+ P K P+ PA+ T + TT A PP P
Sbjct: 1176 AATPPSPKG---GLATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 579 SETPELATEQKPIQDPQPTPSAPAMGAA 606
+ + P P TP +P G A
Sbjct: 1230 GGLATPSPKGAP-TTPAATPPSPKGGPA 1256
Score = 48.1 bits (113), Expect = 3e-05
Identities = 83/369 (22%), Positives = 120/369 (32%), Gaps = 31/369 (8%)
Query: 245 IQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLA--PASPAPARPRSPSQTRKGPP 302
+ G S +A +P S TAS TL SP+P QT++
Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR--- 807
Query: 303 VPPLPKVTPTKELQQENI---ISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPF 359
PP K + + N+ +S E +F+PE S++ + P T P
Sbjct: 808 -PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 360 KPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQS 419
VTP GVT P P + +L P G + Q S+ + ++
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTP-----SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921
Query: 420 MICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGT 479
+ A P+ A P AA P+ + P A P G
Sbjct: 922 RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG----GP 977
Query: 480 LVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKV 539
+ +GAP A AT P+ +G + G T P+ P+
Sbjct: 978 ATPSPKGAPTPPA----ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 540 IPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTS--ETPELATEQKPIQDPQPT 597
P P+ +G T + TT A P P TP L P P T
Sbjct: 1034 TPPAATPPS----PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP---PAAT 1086
Query: 598 PSAPAMGAA 606
P +P G A
Sbjct: 1087 PPSPKGGPA 1095
Score = 48.1 bits (113), Expect = 3e-05
Identities = 95/392 (24%), Positives = 127/392 (32%), Gaps = 36/392 (9%)
Query: 246 QGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPP 305
+G P+ P + A TP PSP SP A+P A PA A P SP + P P
Sbjct: 997 KGGPATPSP-KGAPTPPAVTPPSPKGSPAATPFPKGASTPPA-ATPPSP---KGSPAATP 1051
Query: 306 LPKVTPTKELQQENIISFFEDNFVPEI-SVTTPSQNEVPEVKKEETLLDLDFDPFKPEVT 364
LPK PT + S P + TP P K P P T
Sbjct: 1052 LPKGAPT--TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT 1109
Query: 365 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNL 424
P G +P + P +T P S P+ T S L
Sbjct: 1110 PPSPKGGLATPPHKGAP------TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 425 A-ESEQAPPTEPKAEEPL------------AAVTPAVGLDLGMDTRAEEPVEEAVIIPGA 471
A + PT P A P A TPA A + A P A
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 472 DADAAVGTLVS-AAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEEL 530
+ G L + + +GAP A AT P+ +G G T A P +
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPA----ATPPSPKGGPATPPPKGAPTPPAA--TPPSLKGG 1277
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
AT P + V+ P S + P T + P + P+ A
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 591 IQDPQP--TPSAPAMGAADQLASAREASQELP 620
+ P P TP+ PA + + +S+E P
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Score = 47.4 bits (111), Expect = 5e-05
Identities = 94/376 (25%), Positives = 124/376 (32%), Gaps = 42/376 (11%)
Query: 246 QGAPSDSG--PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPAR-------PRSPSQ 296
+GAP+ S PL PP+E +P PS P PA+PAP + SP +
Sbjct: 862 KGAPTPSAVTPLSPKGVTLPPKE-TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
Query: 297 TR-----KGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETL 351
R KG P P PK PT P+ + T P+ P K
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP-PSPKGGPAT 979
Query: 352 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSL 411
P P TP G +P + P T + P+ GS P+ S
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAP-----TPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 412 FTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGA 471
T S + A PK A TPA L A ++ A P A
Sbjct: 1035 PPAATPPS-----PKGSPAATPLPKG----APTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 472 DADAAV-GTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEEL 530
+ G + +GAP A AT P+ +G G TT A P+
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPA----ATPPSPKGGLATPPHKGAPTTPAATPPSPKG--- 1138
Query: 531 EATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKP 590
P K P+ PA+ T + TT A PP P + + P
Sbjct: 1139 GLATPPPKGAPTT---PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 591 IQDPQPTPSAPAMGAA 606
P TP +P G A
Sbjct: 1196 -TTPAATPPSPKGGLA 1210
Score = 45.4 bits (106), Expect = 2e-04
Identities = 84/385 (21%), Positives = 132/385 (34%), Gaps = 43/385 (11%)
Query: 249 PSDSG-PLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLP 307
PS G P A TP P+EP S + APA+PAP P LP
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM------------GAPTLP 1506
Query: 308 KVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAG 367
V P+ + S D P + T S+ + +E L+ P+ TPA
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAP--TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA- 1563
Query: 368 SAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAES 427
+ + P +S V P+ ++ G P++ + T + S
Sbjct: 1564 ---IPTPKEAPATPSSKEASSPPAVTPS---TYKGAPSPKELLIPPAVT--------SPS 1609
Query: 428 EQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAV-----GTLVS 482
+ PT P P PA G T PV + + + A+V T+
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKG--TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 483 AAEGAP---GEEAEAEKATVPAGEGVSLEEA--KIGTETTEGAESAQPEAEELEATVPQE 537
A++G P G A E PA E + A + G +T + + ++ P + A +
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727
Query: 538 KVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETP-ELATEQKPIQDPQP 596
+ +V P +++ APP + TP A +K + P+
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787
Query: 597 TPSAPAMGAADQLASAREASQELPP 621
+ A L A LPP
Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPP 1812
Score = 43.1 bits (100), Expect = 9e-04
Identities = 53/208 (25%), Positives = 73/208 (35%), Gaps = 29/208 (13%)
Query: 244 TIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAP-ARPRSPSQTRKGPP 302
T +GAPS L SP + +P P P+ PA+PAP P SP P
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP------PV 1642
Query: 303 VPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPE 362
P K +PT + ++ T P ++ KK T L PE
Sbjct: 1643 TPSSLKDSPTSPA-----------SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE 1691
Query: 363 VTPAGSAGVTHSPMSQTLPWDLWTTSTDLV--QPASGGSFNGFTQPQDTSLFTMQTDQSM 420
TP +A P ++ TS + A GS + L +Q D S
Sbjct: 1692 STPIITAPTRKGPQTKKSS----ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747
Query: 421 ICNLAESEQAP-----PTEPKAEEPLAA 443
++ +P P E KA PL A
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTA 1775
Score = 38.9 bits (89), Expect = 0.016
Identities = 82/406 (20%), Positives = 133/406 (32%), Gaps = 48/406 (11%)
Query: 255 LRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG-------------- 300
L + T S +P P T +P TL A P SPS G
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 301 ---PPVPPLPKVTPTKE------LQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETL 351
PV PK PT++ + +++ D+ P + V+ Q + P KK
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGVSVSPQTKRPPTKKGSAG 816
Query: 352 LDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFT----QPQ 407
D V+P ++ + + +S D T+ P+ G+ P+
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 408 DTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVI 467
+L +T + NL ++ P T + P ++T + T A + + +
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS-SPKKARATPAPKGIPASPS 935
Query: 468 IPGADADAAV-------GTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGA 520
GA A G + + AP A AT P+ +G + G T A
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPA----ATPPSPKGGPATPSPKGAPTPPAA 991
Query: 521 ESAQPEA-----EELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPP 575
P+ A P PS PA+ +G + P AA P
Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051
Query: 576 GPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPP 621
P T + P+ P+ P++ A +A S + P
Sbjct: 1052 LPKGAP---TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Score = 37.4 bits (85), Expect = 0.047
Identities = 82/374 (21%), Positives = 118/374 (31%), Gaps = 48/374 (12%)
Query: 240 DKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRK 299
+ +F + + S G T P PSP +PT P++ P P+ + K
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT--------PSAVTPLSPKGVTLPPK 883
Query: 300 GPPVP-----PLPKVTP-TKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLD 353
P P P PK P T +Q +S + P+ + TP+ +P +
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS--PKKARATPAPKGIPASPSPKGA-- 939
Query: 354 LDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFT 413
P P TP G +P + W + P S P+
Sbjct: 940 ----PTPPAATPPSPKGGPATPSPK------WAPTPPAATPPSPKGGPATPSPKGAPTPP 989
Query: 414 MQTDQSMICNLA-ESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGAD 472
T S A S + PT P P +PA A + A P A
Sbjct: 990 AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA----------ATPFPKGASTPPAAT 1039
Query: 473 ADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEA 532
+ G+ AA P AT+P+ +G + G T A P+
Sbjct: 1040 PPSPKGS--PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG---GP 1094
Query: 533 TVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQ 592
P K P + PA+ T + TT A PP P + P
Sbjct: 1095 ATPSPKGAP---MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP-T 1150
Query: 593 DPQPTPSAPAMGAA 606
P TP +P G A
Sbjct: 1151 TPAATPPSPKGGLA 1164
Score = 32.3 bits (72), Expect = 1.5
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 8/59 (13%)
Query: 257 IAKTPSPPEEP--SPLPSPTASPNHTLAPASP-----APARPRSPS-QTRKGPPVPPLP 307
++ PSPP +P P PT P P+SP +P++P +P+ + P +PP P
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 50.4 bits (119), Expect = 5e-06
Identities = 102/429 (23%), Positives = 155/429 (36%), Gaps = 102/429 (23%)
Query: 256 RIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPR-----------SPSQTRKGPPVP 304
R KT SP S PT + + TL PA P SPS + PP P
Sbjct: 155 RTGKTVSPQSNSS---RPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPP 211
Query: 305 PLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVT 364
P P P + +I D F P +P PE K +DPF+P +
Sbjct: 212 PPPPAPPAPPAPRFDIY----DPFHPTDEAYSPP--PAPEQK---------YDPFEPTGS 256
Query: 365 PAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNL 424
S+ T SP + + + + G S ++ +T L + D S+ +
Sbjct: 257 NPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLS-QSISRISET-LAGIYDDNSLSQDF 314
Query: 425 AESE----QAPPTEPKAEEPLAAVTPAVGLDLGMD-TRAEEPVEEAVIIPGADADAA--- 476
E A PT+P TPA G +D TRA+ + V + G +A+A
Sbjct: 315 PGDESPRPDAQPTQP---------TPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREG 365
Query: 477 -VGTLVSAAEGA-------PGEEAEAEKATVPAGEGVSLEEAKIGTET-TEGAESAQPEA 527
V V A GA P ++E E+ + E EE ++ G +A+P
Sbjct: 366 KVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPE----EEPRLALSLFRPGGRAARP-- 419
Query: 528 EELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPK-------ETTEDA-APPGPTS 579
+ P + +P +P + EG++ +++ AE + E A APP S
Sbjct: 420 TPAASATPTAQPLP----QPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADS 475
Query: 580 -------------ETPELATEQKPIQDPQPTPSAPA--------------MGAADQLASA 612
+ E ++ P P P P+A A G A + AS+
Sbjct: 476 RWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASS 535
Query: 613 REASQELPP 621
+Q PP
Sbjct: 536 SSGTQPAPP 544
Score = 30.4 bits (67), Expect = 5.8
Identities = 36/146 (24%), Positives = 46/146 (31%), Gaps = 12/146 (8%)
Query: 476 AVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVP 535
A GT + GEE A+ + P + A T + PE L
Sbjct: 953 AAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEAT 1012
Query: 536 QEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQ 595
+E + E EEE E E E+ P T+ T A P P
Sbjct: 1013 EEAGVRGGAEEEEEEEEEEEEEE----------EEEEQQPATTTATSTAAA--APSTAPS 1060
Query: 596 PTPSAPAMGAADQLASAREASQELPP 621
+A GA D AS LPP
Sbjct: 1061 AGSTAGDSGAEDGPASRVSQLPTLPP 1086
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 50.1 bits (118), Expect = 7e-06
Identities = 86/399 (21%), Positives = 137/399 (34%), Gaps = 58/399 (14%)
Query: 257 IAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRS---------PSQTRK------GP 301
I +P P+EP+P+PSP +P P P P + RS S TR+ P
Sbjct: 567 ITTSPPVPQEPAPVPSPPRAPTPPSTPV-PLPEKRRSILREPTFRWTSLTRELPPPPPAP 625
Query: 302 PVPPLPKVTPTKELQQENIISFFEDNFVPE-------ISVTTPSQNEVPEVKKEETLLDL 354
P PP P P + F P SV TP PE + E
Sbjct: 626 PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP-PPA 684
Query: 355 DFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTM 414
D P +PE P H + + P + T V P + + Q Q L +
Sbjct: 685 DDSPAEPE--PRAVGRTNHLSLPRFAP-VVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL 741
Query: 415 QTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVI-----IP 469
Q Q+ + + PP +P+ + P + P+E+A I +P
Sbjct: 742 QALQTQLL----PQALPPPQPQLQPP-------------PSPQQMPPLEKARIAGVGSLP 784
Query: 470 GADADAAVGTLVSAAE----GAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQP 525
+ + + +L+ A+ ++ + A++P G +EE + +
Sbjct: 785 LSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRS 844
Query: 526 EAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPG--PTSETPE 583
E E +EA + S V P H + +G ED P + +
Sbjct: 845 EDESVEAKRERPSGPESPVQGPRIKHVCR-HAAVALGQARAMVPEDVPRLSALPLRDRQD 903
Query: 584 LATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPG 622
LATE T S P+ ++ +A + P G
Sbjct: 904 LATED--TSSASETESVPSRSRRGKVEAAGPGGESEPTG 940
Score = 46.2 bits (108), Expect = 1e-04
Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 9/130 (6%)
Query: 249 PSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPK 308
PS S P + P PP P PLPSP P SP P P + S+ R PP
Sbjct: 420 PSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPP------ 473
Query: 309 VTPTKELQQENIISFFEDNFVPEISVTTPS---QNEVPEVKKEETLLDLDFDPFKPEVTP 365
+TP++ ++E + E P + +T + + P V + T + F V
Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVS 533
Query: 366 AGSAGVTHSP 375
A S+ V +P
Sbjct: 534 ARSSRVIKTP 543
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 10/60 (16%)
Query: 260 TPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQEN 319
TP P P PLP P+ SP L P P P P PP+P P P +E Q+E+
Sbjct: 407 TPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP---------PPLPS-PPPPPAQEEQEES 456
Score = 38.5 bits (88), Expect = 0.021
Identities = 73/390 (18%), Positives = 124/390 (31%), Gaps = 35/390 (8%)
Query: 253 GPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPT 312
GPL +PS P P P+P PR P PP+ P++
Sbjct: 1883 GPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP 1942
Query: 313 KELQQENIISFFEDNFVPEISVTTPSQNE--VPEVKKEETL-----LDLDF-------DP 358
++ P +P E P+ + E + DLDF +P
Sbjct: 1943 PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEP 2002
Query: 359 FKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQ 418
F+ E+ AG+ G +H + + TS + P + S G P T
Sbjct: 2003 FQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA-PSATPGAPRIEQL 2061
Query: 419 SMICNLAESEQAPPTEPKAE--EPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAA 476
+ + +SE +P+ + P G+ RA P + +P D
Sbjct: 2062 DGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPED----LPSEIVDFV 2117
Query: 477 VGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQ 536
+ L +G G E+ P G++ ++G ++ + A +P
Sbjct: 2118 LKNLGGPGDGGAGPREESLPPAPPLAN---------GSQPSQGLTASPADPTRTFAWLPG 2168
Query: 537 EKVIPSVVIEPASNHEEEGENEITIGAE-----PKETTEDAAPPGPTSETPELATEQKPI 591
+ + + PA + ++I + + K E P P + P T
Sbjct: 2169 APGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA 2228
Query: 592 QDPQPTPSAPAMGAADQLASAREASQELPP 621
P P +G + R A PP
Sbjct: 2229 PTSWTLPPGPLLGVLPVVGVVRPAPPPPPP 2258
Score = 35.0 bits (79), Expect = 0.23
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 20/129 (15%)
Query: 499 VPAGEGVS----LEEAKIGTETTEGAESAQP--EAEELEATVPQEKVIPSVVIEPASNHE 552
V +G+G S +E K+ E E E + E EE E E+++P+ +
Sbjct: 344 VGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAA-------EK 396
Query: 553 EEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASA 612
EE + P + PP TS P L P P P PS P A
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPP-------PPA 449
Query: 613 REASQELPP 621
+E +E PP
Sbjct: 450 QEEQEESPP 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,231,255
Number of Sequences: 37866
Number of extensions: 1782979
Number of successful extensions: 25207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 1285
Number of HSP's that attempted gapping in prelim test: 13647
Number of HSP's gapped (non-prelim): 8580
length of query: 695
length of database: 18,247,518
effective HSP length: 109
effective length of query: 586
effective length of database: 14,120,124
effective search space: 8274392664
effective search space used: 8274392664
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.