Guide to the Human Genome
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Search of human proteins with 4501929

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
         (375 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...   758   0.0  
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...   717   0.0  
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...   710   0.0  
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ...   546   e-155
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...   493   e-139
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]   483   e-137
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]     477   e-135
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap...   461   e-130
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                    100   3e-21
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                 61   1e-09
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                  61   1e-09
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    58   2e-08
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                 54   3e-07
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           49   6e-06
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    45   1e-04
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    43   4e-04
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...    40   0.004
gi|41872631 fatty acid synthase [Homo sapiens]                         39   0.008
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       37   0.022
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       37   0.022
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     33   0.42 
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        30   3.5  
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        30   3.5  
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        30   3.5  
gi|194018457 N-acetylgalactosaminyltransferase-like 6 [Homo sapi...    30   3.5  
gi|83367077 mucin 16 [Homo sapiens]                                    29   6.0  
gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]                29   6.0  
gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]                29   6.0  
gi|222831587 tRNA methyltransferase 61 homolog B [Homo sapiens]        29   7.9  
gi|58197558 tudor domain containing 6 [Homo sapiens]                   29   7.9  

>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score =  758 bits (1957), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60
           MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT
Sbjct: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120

Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300

Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
           NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF
Sbjct: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360

Query: 361 DLLHSGKSIRTILMF 375
           DLLHSGKSIRTILMF
Sbjct: 361 DLLHSGKSIRTILMF 375


>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score =  717 bits (1850), Expect = 0.0
 Identities = 351/375 (93%), Positives = 363/375 (96%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60
           MSTAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVAVGIC TDDHVVSG +VT
Sbjct: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL  PQCGKCR+CKNPESNYCLKND+ NP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120

Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +GTLQDGT RFTCR KPIHHFLG STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAVNVAKVTPGSTCAVFGLGGVGLSA+MGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300

Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
           NLS+NPMLLLTGRTWKGA+ GGFKSKE +PKLVADFMAKKFSLDALITHVLPFEKINEGF
Sbjct: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360

Query: 361 DLLHSGKSIRTILMF 375
           DLLHSGKSIRT+L F
Sbjct: 361 DLLHSGKSIRTVLTF 375


>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score =  710 bits (1833), Expect = 0.0
 Identities = 348/375 (92%), Positives = 360/375 (96%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60
           MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVA GIC +D+HVVSG +VT
Sbjct: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL  PQCGKCRICKNPESNYCLKND+ NP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120

Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +GTLQDGT RFTC  KPIHHF+G+STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAV VAKVTPGSTCAVFGLGGVGLS +MGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300

Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
           NLS+NPMLLLTGRTWKGAI GGFKSKE VPKLVADFMAKKFSLDALIT++LPFEKINEGF
Sbjct: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360

Query: 361 DLLHSGKSIRTILMF 375
           DLL SGKSIRT+L F
Sbjct: 361 DLLRSGKSIRTVLTF 375


>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
           [Homo sapiens]
          Length = 386

 Score =  546 bits (1407), Expect = e-155
 Identities = 257/375 (68%), Positives = 313/375 (83%), Gaps = 1/375 (0%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60
           M TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK  EVRIK++A GIC TDDHV+ GTMV+
Sbjct: 13  MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS 72

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120
             PVI+GHEA GIVES+GEGVTTVKPGDKVIPL +PQC +C  C+NP+ N C+++D++  
Sbjct: 73  KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG- 131

Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +G L DGT+RFTC+ KP+HHF+  STF++YTVVDE++VAKID A+P EKVCLIGCGFSTG
Sbjct: 132 RGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YG+AV   KV PGSTC VFGLGGVGLS IMGCK+AGA+RII +D+NKDKF KA  +GATE
Sbjct: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CI+P+D  KPI EVL EMT   V ++FEVIG L+TM+ +L  CH   GTSV+VGVPP ++
Sbjct: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311

Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
            L+ +PMLL TGRTWKG + GG KS++ VPKLV +F+AKKF LD LITHVLPF+KI+EGF
Sbjct: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371

Query: 361 DLLHSGKSIRTILMF 375
           +LL+SG+SIRT+L F
Sbjct: 372 ELLNSGQSIRTVLTF 386


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score =  493 bits (1269), Expect = e-139
 Identities = 237/371 (63%), Positives = 290/371 (78%), Gaps = 1/371 (0%)

Query: 4   AGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP-L 62
           A +VIKCKAAV WE  KP SIEE+EVAPPKAHEVRIK++A  +C TD + +SG       
Sbjct: 2   ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61

Query: 63  PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG 122
           PVILGHE AGIVESVGEGVT +K GD VIPL IPQCG+C+ C NP++N C K  V+  +G
Sbjct: 62  PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121

Query: 123 TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182
            + DGTSRFTC+ K I H++G STFS+YTVV + +VAKID  +PL+KVCL+GCG STGYG
Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181

Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242
           +AVN AK+ PGS CAVFGLGGVGL+ IMGCK AGA+RII VDINKDKFA+AKE GATECI
Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241

Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302
           NPQD+ KPIQEVL EMTDGGVD+SFE IG +  M A+L  CH+  G SV+VGV    + +
Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301

Query: 303 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
           +  P  L+TGRTWKG   GG+KS E VPKLV+++M+KK  +D  +TH L F++IN+ F+L
Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361

Query: 363 LHSGKSIRTIL 373
           +HSGKSIRT++
Sbjct: 362 MHSGKSIRTVV 372


>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
          Length = 375

 Score =  483 bits (1244), Expect = e-137
 Identities = 238/375 (63%), Positives = 294/375 (78%), Gaps = 2/375 (0%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60
           MST G+VI+CKAA+LW+   PFSIEEVEVAPPKA EVRIK+VA G+CGT+  V+    + 
Sbjct: 1   MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD 60

Query: 61  PL-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN 119
            L P ILGHE AGIVES+GEGV+TVKPGDKVI L +PQCG+C  C N E N+C++   S 
Sbjct: 61  LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK 120

Query: 120 PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179
            Q  + DGTSRFTC+ K I+HF   STF +YTV+ E +VAKIDA +PLEKVCLI CGFST
Sbjct: 121 TQ-LMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           G+G+A+N AKVTPGSTCAVFGLGGVGLS +MGCKAAGAARII VD+NK+KF KA+ELGAT
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGAT 239

Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299
           EC+NPQD KKPIQEVL +MTD G+DF FE IG LD + A+L  C+E+ G  V+VGV P S
Sbjct: 240 ECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPAS 299

Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359
             L ++  L  +GR+ KG++ GG+KS++ +PKLVAD+MA+K +LD LITH L  +KINE 
Sbjct: 300 VQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEA 359

Query: 360 FDLLHSGKSIRTILM 374
            +L+ +GK IR IL+
Sbjct: 360 VELMKTGKCIRCILL 374


>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
          Length = 368

 Score =  477 bits (1227), Expect = e-135
 Identities = 234/368 (63%), Positives = 289/368 (78%), Gaps = 2/368 (0%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60
           MST G+VI+CKAA+LW+   PFSIEEVEVAPPKA EVRIK+VA G+CGT+  V+    + 
Sbjct: 1   MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD 60

Query: 61  PL-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN 119
            L P ILGHE AGIVES+GEGV+TVKPGDKVI L +PQCG+C  C N E N+C++   S 
Sbjct: 61  LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK 120

Query: 120 PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179
            Q  + DGTSRFTC+ K I+HF   STF +YTV+ E +VAKIDA +PLEKVCLI CGFST
Sbjct: 121 TQ-LMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           G+G+A+N AKVTPGSTCAVFGLGGVGLS +MGCKAAGAARII VD+NK+KF KA+ELGAT
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGAT 239

Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299
           EC+NPQD KKPIQEVL +MTD G+DF FE IG LD + A+L  C+E+ G  V+VGV P S
Sbjct: 240 ECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPAS 299

Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359
             L ++  L  +GR+ KG++ GG+KS++ +PKLVAD+MA+K +LD LITH L  +KINE 
Sbjct: 300 VQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEA 359

Query: 360 FDLLHSGK 367
            +L+ +GK
Sbjct: 360 VELMKTGK 367


>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
           sapiens]
          Length = 380

 Score =  461 bits (1187), Expect = e-130
 Identities = 229/381 (60%), Positives = 285/381 (74%), Gaps = 7/381 (1%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV- 59
           M T GKVIKCKAA+ WE  KP  IEEVEVAPPKAHEVRI+++A  +C TD  V+      
Sbjct: 1   MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYC-----LK 114
              PVI+GHEAAGIVES+G GVT VKPGDKVIPL  P C KC+ C +P +N C     LK
Sbjct: 61  LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120

Query: 115 NDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIG 174
           +  S+ Q  ++D TSRFTC+ KP++HF G STFSQYTVV +  +AKID  + LE+VCL+G
Sbjct: 121 SPASDQQ-LMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG 179

Query: 175 CGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK 234
           CGFSTGYG+A+N AKVTPGSTCAVFGLGGVGLSA+MGCKAAGA+RII +DIN +KF KAK
Sbjct: 180 CGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239

Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294
            LGAT+C+NP+D  KPIQEV+ E+T GGVDF+ +  G  +TM A+L C     G+   +G
Sbjct: 240 ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 299

Query: 295 VPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFE 354
           V   S+ L++ P  L+ GRT  G   GG+KS + +PKLV D+  KKF+LDAL+TH LPF+
Sbjct: 300 VAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFD 359

Query: 355 KINEGFDLLHSGKSIRTILMF 375
           KI+E FDL++ GKS+RTIL+F
Sbjct: 360 KISEAFDLMNQGKSVRTILIF 380


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score =  100 bits (248), Expect = 3e-21
 Identities = 97/362 (26%), Positives = 156/362 (43%), Gaps = 47/362 (12%)

Query: 24  IEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESVGE 79
           +E   +  P  +EV ++M +VGICG+D H       G  +   P++LGHEA+G VE VG 
Sbjct: 22  LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81

Query: 80  GVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP-- 137
            V  +KPGD+V   AI            E     +ND     G      S F C   P  
Sbjct: 82  SVKHLKPGDRV---AI------------EPGAPRENDEFCKMGRYNLSPSIFFCATPPDD 126

Query: 138 --IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195
             +  F   +    Y + D     +     PL          S G   A     VT G  
Sbjct: 127 GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLGHK 175

Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255
             V G G +G+  ++  KA GAA+++  D++  + +KAKE+GA   +  Q  K+  QE+ 
Sbjct: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQEIA 233

Query: 256 KEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLT 311
           +++ +G +    + + E  G   ++ A +       G  V+VG+  +     M  + LL 
Sbjct: 234 RKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLLH 286

Query: 312 GRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRT 371
               +  I G F+     P  ++   +K  ++  L+TH  P EK  E F+    G  ++ 
Sbjct: 287 AAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKI 346

Query: 372 IL 373
           +L
Sbjct: 347 ML 348


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 61/272 (22%), Positives = 111/272 (40%), Gaps = 54/272 (19%)

Query: 26  EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESVGEGVTT 83
           ++ V  PK H+V IK+ A G+   + ++ SGT      LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143
            K GD+V                                T+  G                
Sbjct: 87  FKKGDRVF----------------------------TSSTISGG---------------- 102

Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262
           GVGL+A    +A G  +I+     ++      + GA E  N ++    I ++ K + + G
Sbjct: 160 GVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKG 217

Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294
           +D   E++  ++      L  H   G  ++VG
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHG--GRVIVVG 247


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 61/272 (22%), Positives = 111/272 (40%), Gaps = 54/272 (19%)

Query: 26  EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESVGEGVTT 83
           ++ V  PK H+V IK+ A G+   + ++ SGT      LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143
            K GD+V                                T+  G                
Sbjct: 87  FKKGDRVF----------------------------TSSTISGG---------------- 102

Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262
           GVGL+A    +A G  +I+     ++      + GA E  N ++    I ++ K + + G
Sbjct: 160 GVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKG 217

Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294
           +D   E++  ++      L  H   G  ++VG
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHG--GRVIVVG 247


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 59/247 (23%), Positives = 97/247 (39%), Gaps = 56/247 (22%)

Query: 20  KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT--MVTPLPVILGHEAAGIVESV 77
           K   ++ +E+A  +  +VR+KM+A  I  +D +++ G    +  LP + G+E    V +V
Sbjct: 56  KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAV 115

Query: 78  GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 137
           G  VT +KPGD VIP                                             
Sbjct: 116 GSNVTGLKPGDWVIPAN------------------------------------------- 132

Query: 138 IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STC 196
                G+ T+    V  E A+ ++ +  PL+    +G    T Y   ++  ++ PG S  
Sbjct: 133 ----AGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 188

Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAV----DINKDKFAKAKELGATECINPQDYKKP-I 251
                 GVG + I    A G   I  V    DI K    + K LGA   I  ++ ++P +
Sbjct: 189 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEM 247

Query: 252 QEVLKEM 258
           +   K+M
Sbjct: 248 KNFFKDM 254


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 50/194 (25%)

Query: 26  EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESVGEGVTT 83
           ++ V  PK H+V IK+ A G+   + ++ SGT      LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143
            K GD+V                                T+  G                
Sbjct: 87  FKKGDRVF----------------------------TSSTISGG---------------- 102

Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSAIMGCKAAG 216
           GVGL+A    +A G
Sbjct: 160 GVGLAACQIARAYG 173


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 80/339 (23%), Positives = 123/339 (36%), Gaps = 83/339 (24%)

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120
           PLPV  G E AG+V +VGEGV+  K GD+V+                         V N 
Sbjct: 105 PLPVTPGMEGAGVVIAVGEGVSDRKAGDRVM-------------------------VLNR 139

Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
            G  Q+  +              + TF             I  A   E+   +   + T 
Sbjct: 140 SGMWQEEVT-----------VPSVQTF------------LIPEAMTFEEAAALLVNYITA 176

Query: 181 YGSAVNVAKVTPGSTCAV-FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           Y    +   + PG +  V    GGVG++A+  C+      +     +  K    KE G T
Sbjct: 177 YMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVT 235

Query: 240 ECINPQDY-KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298
              +P DY      + +K+++  GVD   + +G  DT     L   +  G  V  G+   
Sbjct: 236 ---HPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLL--KPMGKVVTYGM--- 287

Query: 299 SQNLSMNPM--LLLTGRTW------------------KGAILGGFKSK-ECVPKLVADFM 337
             NL   P   L+   RTW                   G  LG    + E V  +VA  +
Sbjct: 288 -ANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLL 346

Query: 338 A--KKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILM 374
           A   +  +   I  V PFEK+ +    +   K++  +L+
Sbjct: 347 ALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 53/226 (23%), Positives = 84/226 (37%), Gaps = 56/226 (24%)

Query: 41  MVAVGICGTDDHVVSGT--MVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQC 98
           M+A  I  +D +++ G    +  LP + G+E    V +VG  VT +KPGD VIP      
Sbjct: 1   MLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPAN---- 56

Query: 99  GKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAV 158
                                                       G+ T+    V  E A+
Sbjct: 57  -------------------------------------------AGLGTWRTEAVFSEEAL 73

Query: 159 AKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STCAVFGLGGVGLSAIMGCKAAGA 217
            ++ +  PL+    +G    T Y   ++  ++ PG S        GVG + I    A G 
Sbjct: 74  IQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGL 133

Query: 218 ARIIAV----DINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 258
             I  V    DI K    + K LGA   I  ++ ++P ++   K+M
Sbjct: 134 RTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEMKNFFKDM 178


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 8/133 (6%)

Query: 141 FLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG 200
           ++   +F++YTVV  +    + +  P E + L+  G +T Y S   +  ++ G    V  
Sbjct: 123 YMAPGSFAEYTVVPASIATPVPSVKP-EYLTLLVSG-TTAYISLKELGGLSEGKKVLVTA 180

Query: 201 L-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KPIQEVLKEM 258
             GG G  A+   K A    +I    + +K A  K LG   C  P +YK +P+  VLK+ 
Sbjct: 181 AAGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLG---CDRPINYKTEPVGTVLKQE 236

Query: 259 TDGGVDFSFEVIG 271
              GVD  +E +G
Sbjct: 237 YPEGVDVVYESVG 249


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 2/89 (2%)

Query: 32  PKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESVGEGVTTVKPGDK 89
           P+  E++I++ A G+   D  V  G +  P   P++ G E +GIVE++G+ V   + GD+
Sbjct: 66  PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 125

Query: 90  VIPLAIPQCGKCRICKNPESNYCLKNDVS 118
           V+           +C   E  Y + +D+S
Sbjct: 126 VMAFVNYNAWAEVVCTPVEFVYKIPDDMS 154


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 7/161 (4%)

Query: 167  LEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAV-D 224
            LE+   +   +ST Y + V   +V PG T  +  G GGVG +AI    + G      V  
Sbjct: 1642 LEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGS 1701

Query: 225  INKDKFAKAK--ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLC 282
              K  + +A+  +L +T   N +D     Q VL      GVD     +   + + AS+ C
Sbjct: 1702 AEKRAYLQARFPQLDSTSFANSRDTSFE-QHVLWHTGGKGVDLVLNSLAE-EKLQASVRC 1759

Query: 283  CHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGF 323
                 G  + +G    SQN  +   + L   T+ G +L  F
Sbjct: 1760 L-ATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAF 1799


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155

Query: 207 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
           +AI   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211

Query: 265 FSFEVIG 271
              + IG
Sbjct: 212 LILDCIG 218


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155

Query: 207 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
           +AI   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211

Query: 265 FSFEVIG 271
              + IG
Sbjct: 212 LILDCIG 218


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 33.1 bits (74), Expect = 0.42
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 10/95 (10%)

Query: 66  LGHEAAGIVESVGEGVTTVKPGDKVI---PLAIPQCGKCRICKNPESNYCLKNDV---SN 119
           +G E AGIV  VG  V+  +P D+V+   PL     G C + +  E     K +    + 
Sbjct: 62  VGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTE 121

Query: 120 PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVD 154
             G+++DG   +T     +H+   +S      ++D
Sbjct: 122 AAGSIRDGVRAYTA----LHYLSHLSPGKSVLIMD 152


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAIMGCKAAGAARIIAVDIN 226
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAIMGCKAAGAARIIAVDIN 226
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAIMGCKAAGAARIIAVDIN 226
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|194018457 N-acetylgalactosaminyltransferase-like 6 [Homo
           sapiens]
          Length = 601

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 10/58 (17%)

Query: 6   KVIKCK------AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT 57
           K +KCK      AAV W++ K +      V PP A    I+ VA  +C    H  +GT
Sbjct: 423 KQLKCKDFKWFMAAVAWDVPKYYP----PVEPPPAAWGEIRNVAANLCVDSKHGATGT 476


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 41/164 (25%), Positives = 62/164 (37%), Gaps = 16/164 (9%)

Query: 28   EVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPG 87
            E +   A E R     V + GT   +V+      +   LG  ++ + ES  EGVT    G
Sbjct: 1659 ETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKG 1718

Query: 88   DKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTF 147
                P    Q G   +  + E +Y   + +S         T+       P   F+G STF
Sbjct: 1719 SS--PRLNTQ-GNTALSSSLEPSYAEGSQMSTSIPLTSSPTT-------PDVEFIGGSTF 1768

Query: 148  --SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189
               + T V  + ++K  A +      L+    ST  GS  N  K
Sbjct: 1769 WTKEVTTVMTSDISKSSARTESSSATLM----STALGSTENTGK 1808


>gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]
          Length = 587

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAA 218
           +G  F T +GS +     + G   +   LGG G S+  GC   GA+
Sbjct: 472 LGVSFGTPFGSGIGTGLQSSGLGSS--NLGGFGTSSGFGCSTTGAS 515


>gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]
          Length = 599

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAA 218
           +G  F T +GS +     + G   +   LGG G S+  GC   GA+
Sbjct: 484 LGVSFGTPFGSGIGTGLQSSGLGSS--NLGGFGTSSGFGCSTTGAS 527


>gi|222831587 tRNA methyltransferase 61 homolog B [Homo sapiens]
          Length = 477

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 13/51 (25%), Positives = 24/51 (47%)

Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235
           +++  + PG T    G G  G+S  +        R+I+ ++ KD    AK+
Sbjct: 239 LSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK 289


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 8/91 (8%)

Query: 192 PGSTCAVFGLGGVGLSAIM--GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249
           PGS CA  GL G    A++    +    A+++ VD  + +      L     + P+ ++ 
Sbjct: 313 PGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSL---RYLLPEYFRM 369

Query: 250 PIQE---VLKEMTDGGVDFSFEVIGRLDTMM 277
           P+      L  + DGG  +S   +G L T++
Sbjct: 370 PVVTYPCALYGLWDGGRGWSRSQVGDLKTLI 400


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,490,798
Number of Sequences: 37866
Number of extensions: 621537
Number of successful extensions: 1505
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1470
Number of HSP's gapped (non-prelim): 36
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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