Guide to the Human Genome
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Name: FASN Sequence: fasta or formatted (2511aa) NCBI GI: 41872631
Description:

fatty acid synthase

Referenced in:

Domain Structure of Proteins
Fatty Acid Synthesis

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.0        226           3
 C cysteine            1.8         46           1
 D aspartate           4.6        116           3
 E glutamate           5.9        149           2
 F phenylalanine       3.5         88           3
 G glycine             8.2        206           2
 H histidine           2.7         68           1
 I isoleucine          3.6         91           2
 K lysine              3.4         85           2
 L leucine            12.6        316           3
 M methionine          1.7         43           2
 N asparagine          2.7         67           2
 P proline             5.9        149           3
 Q glutamine           4.9        124           3
 R arginine            5.7        142           2
 S serine              7.9        199           3
 T threonine           4.6        115           2
 V valine              7.7        193           3
 W tryptophan          1.3         33           1
 Y tyrosine            2.2         55           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   fatty acid synthase 
OXSM                  0.016   3-oxoacyl-ACP synthase, mitochondrial isoform 1 precu...
TP53I3                0.016   tumor protein p53 inducible protein 3 
TP53I3                0.016   tumor protein p53 inducible protein 3 
CRYZ                  0.012   crystallin, zeta isoform a 
CRYZ                  0.012   crystallin, zeta isoform a 
VAT1L                 0.009   vesicle amine transport protein 1 homolog (T. califo...
ZADH2                 0.009   zinc binding alcohol dehydrogenase domain containing...
CRYZ                  0.009   crystallin, zeta isoform c 
LY9                   0.008   lymphocyte antigen 9 isoform b 
VAT1                  0.008   vesicle amine transport protein 1 
CRYZ                  0.007   crystallin, zeta isoform b 
LOC100293681          0.006   PREDICTED: similar to Putative uncharacterized prot...
LOC100290712          0.006   PREDICTED: hypothetical protein XP_002347152 
LOC100289548          0.006   PREDICTED: hypothetical protein XP_002343020 
OXSM                  0.006   3-oxoacyl-ACP synthase, mitochondrial isoform 2 pre...
CRYZL1                0.005   crystallin, zeta-like 1 
MECR                  0.005   trans-2-enoyl-CoA reductase, mitochondrial isoform b...
MECR                  0.005   trans-2-enoyl-CoA reductase, mitochondrial isoform a...
PTGR1                 0.005   prostaglandin reductase 1 isoform 1 
PTGR1                 0.005   prostaglandin reductase 1 isoform 1 
MCAT                  0.005   mitochondrial malonyltransferase isoform a precursor...
PTGR1                 0.005   prostaglandin reductase 1 isoform 2 
ADH1A                 0.003   class I alcohol dehydrogenase, alpha subunit 
ADH1C                 0.003   class I alcohol dehydrogenase, gamma subunit 
ADH4                  0.003   class II alcohol dehydrogenase, pi subunit 
ADH1B                 0.002   class I alcohol dehydrogenase, beta subunit 
HSD17B4               0.002   hydroxysteroid (17-beta) dehydrogenase 4 
HK3                   0.002   hexokinase 3 
ADH6                  0.002   class V alcohol dehydrogenase isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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