BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] (352 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 721 0.0 gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 686 0.0 gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 684 0.0 gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 205 6e-53 gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 182 3e-46 gi|112789532 poliovirus receptor related 2 isoform delta precurs... 182 3e-46 gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 174 8e-44 gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 174 8e-44 gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 174 8e-44 gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 174 8e-44 gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 138 8e-33 gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 77 2e-14 gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 77 2e-14 gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 70 2e-12 gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 70 2e-12 gi|90903245 CD200 antigen isoform b [Homo sapiens] 69 6e-12 gi|90903247 CD200 antigen isoform a precursor [Homo sapiens] 69 6e-12 gi|21686977 cell adhesion molecule 4 [Homo sapiens] 67 3e-11 gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 64 2e-10 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 62 6e-10 gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 60 4e-09 gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 60 4e-09 gi|126517478 peroxidasin homolog-like [Homo sapiens] 60 4e-09 gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 56 4e-08 gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 56 4e-08 gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 56 4e-08 gi|67188443 CD276 antigen isoform a [Homo sapiens] 53 4e-07 gi|166295173 kin of IRRE like [Homo sapiens] 53 4e-07 gi|13376852 CD276 antigen isoform b [Homo sapiens] 53 5e-07 gi|4505243 myelin protein zero [Homo sapiens] 53 5e-07 >gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] Length = 352 Score = 721 bits (1862), Expect = 0.0 Identities = 352/352 (100%), Positives = 352/352 (100%) Query: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV Sbjct: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60 Query: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG Sbjct: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120 Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240 Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300 Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAFCQLIYPGKGRTRARMF 352 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAFCQLIYPGKGRTRARMF Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAFCQLIYPGKGRTRARMF 352 >gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] Length = 517 Score = 686 bits (1769), Expect = 0.0 Identities = 335/336 (99%), Positives = 335/336 (99%) Query: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV Sbjct: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60 Query: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG Sbjct: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120 Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240 Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300 Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAF 336 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT F Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEF 336 >gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] Length = 458 Score = 684 bits (1764), Expect = 0.0 Identities = 334/334 (100%), Positives = 334/334 (100%) Query: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV Sbjct: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60 Query: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG Sbjct: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120 Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240 Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300 Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334 Score = 28.5 bits (62), Expect = 9.5 Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 1/27 (3%) Query: 120 GVYICEFATFPTGNRESQLNLTVMAKP 146 G YICE AT P G R Q+ + + KP Sbjct: 312 GTYICE-ATNPIGTRSGQVEVNITEKP 337 >gi|11386199 poliovirus receptor-related 3 [Homo sapiens] Length = 549 Score = 205 bits (521), Expect = 6e-53 Identities = 107/276 (38%), Positives = 160/276 (57%), Gaps = 8/276 (2%) Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGV 121 ITQ++W+K S Q VA+++P G SV Y+ RV F S D TI L + D G Sbjct: 86 ITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGK 145 Query: 122 YICEFATFPTGNRESQLNLTVMAKPT-NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180 YIC+ TFP GN +S +TV+ +PT + I+G +++ ++ + A C +A GKP Sbjct: 146 YICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDG----GNETVAAICIAATGKPV 201 Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKES 238 + + WE L GE E PN T T+IS+Y+L P+R A + + C+V + + S Sbjct: 202 AHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260 Query: 239 LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNR 298 L++QY PEV++ G+DGNW++ R V L C ADANPP + W+ L+G P G+ A + Sbjct: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDN 320 Query: 299 TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334 TL F P+ ++ +G YIC+ TN +G RS Q + I+ Sbjct: 321 TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYIS 356 >gi|5360210 poliovirus receptor related 2 isoform alpha precursor [Homo sapiens] Length = 479 Score = 182 bits (463), Expect = 3e-46 Identities = 115/315 (36%), Positives = 160/315 (50%), Gaps = 26/315 (8%) Query: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85 G VQV + G +G V L C P+P + I+ VTWQ+ + QNVA ++P M Sbjct: 30 GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89 Query: 86 GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133 G S +P ER+ F+ D T+ L L +EDEG Y CEFATFP G+ Sbjct: 90 GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149 Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193 L V+AKP N E + D VA C S G+PP+ +SW + L EA Sbjct: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204 Query: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248 + ++ GTVTV SR+ LVPS A ++ C V + + F+E +TL+V+Y PE Sbjct: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262 Query: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308 V+I G+D NWYL R D L+C +NP T Y W+T +G+ P AQ L ++ Sbjct: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321 Query: 309 SLAGTYICEATNPIG 323 T++C TN +G Sbjct: 322 LFNTTFVCTVTNAVG 336 >gi|112789532 poliovirus receptor related 2 isoform delta precursor [Homo sapiens] Length = 538 Score = 182 bits (463), Expect = 3e-46 Identities = 115/315 (36%), Positives = 160/315 (50%), Gaps = 26/315 (8%) Query: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85 G VQV + G +G V L C P+P + I+ VTWQ+ + QNVA ++P M Sbjct: 30 GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89 Query: 86 GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133 G S +P ER+ F+ D T+ L L +EDEG Y CEFATFP G+ Sbjct: 90 GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149 Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193 L V+AKP N E + D VA C S G+PP+ +SW + L EA Sbjct: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204 Query: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248 + ++ GTVTV SR+ LVPS A ++ C V + + F+E +TL+V+Y PE Sbjct: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262 Query: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308 V+I G+D NWYL R D L+C +NP T Y W+T +G+ P AQ L ++ Sbjct: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321 Query: 309 SLAGTYICEATNPIG 323 T++C TN +G Sbjct: 322 LFNTTFVCTVTNAVG 336 >gi|209413732 poliovirus receptor isoform delta [Homo sapiens] Length = 392 Score = 174 bits (442), Expect = 8e-44 Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%) Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61 +A A W L AL + ++ PG VVQ + GF+G V L C P V Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60 Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117 ++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116 Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177 DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171 Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236 +PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V + Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231 Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294 + LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291 Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 AQ L + P++ + T IC TN +G R ++ V + Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329 >gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] Length = 364 Score = 174 bits (442), Expect = 8e-44 Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%) Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61 +A A W L AL + ++ PG VVQ + GF+G V L C P V Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60 Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117 ++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116 Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177 DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171 Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236 +PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V + Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231 Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294 + LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291 Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 AQ L + P++ + T IC TN +G R ++ V + Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329 >gi|209413728 poliovirus receptor isoform beta [Homo sapiens] Length = 372 Score = 174 bits (442), Expect = 8e-44 Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%) Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61 +A A W L AL + ++ PG VVQ + GF+G V L C P V Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60 Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117 ++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116 Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177 DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171 Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236 +PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V + Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231 Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294 + LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291 Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 AQ L + P++ + T IC TN +G R ++ V + Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329 >gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] Length = 417 Score = 174 bits (442), Expect = 8e-44 Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%) Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61 +A A W L AL + ++ PG VVQ + GF+G V L C P V Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60 Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117 ++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116 Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177 DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171 Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236 +PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V + Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231 Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294 + LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291 Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 AQ L + P++ + T IC TN +G R ++ V + Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329 >gi|222136611 poliovirus receptor-related 4 [Homo sapiens] Length = 510 Score = 138 bits (347), Expect = 8e-33 Identities = 102/341 (29%), Positives = 164/341 (48%), Gaps = 20/341 (5%) Query: 4 MGLAGAAGRW----WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPS 59 M L+ A W W L L L A F + ++ +D + +G D L C + Sbjct: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SG 59 Query: 60 VKITQVTWQKSTNGS-KQNVAIYNPSMGVSVLAPYRERVEFLRPSFT--DGTIRLSRLEL 116 ++ QV W + G Q +A+ + G+ V Y RVE P DG++ L Sbjct: 60 EQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQ 119 Query: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176 DEG Y C +TFP G+ +++L L V+ P + A+ ++GQ L A+CT A Sbjct: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL---EEGQ-GLTLAASCT-AE 174 Query: 177 GKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236 G P V+W+T +KG + ++ + + V S + LVPSR + Q L C+V++ Sbjct: 175 GSPAPSVTWDTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233 Query: 237 ESLT--LNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292 + +T L+V + E ++ G + W++ R L C ++ PP + Y+WT L+G LP G Sbjct: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSG 292 Query: 293 VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 V TL F P+ +G Y+C +N +R QV V++ Sbjct: 293 VRVDGDTLGFP-PLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332 >gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo sapiens] Length = 414 Score = 77.0 bits (188), Expect = 2e-14 Identities = 69/260 (26%), Positives = 117/260 (45%), Gaps = 27/260 (10%) Query: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133 + + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P Sbjct: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131 Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190 +ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK Sbjct: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187 Query: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248 G++E +E + TV S+ L +E + C V + + L VQY+P+ Sbjct: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244 Query: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303 V I+ + LQ + ++LTC+A P W ++ +P+ LF Sbjct: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301 Query: 304 GPINYSLAGTYICEATNPIG 323 +N + GTY CEA+N +G Sbjct: 302 N-LNKTDNGTYRCEASNIVG 320 >gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo sapiens] Length = 442 Score = 77.0 bits (188), Expect = 2e-14 Identities = 69/260 (26%), Positives = 117/260 (45%), Gaps = 27/260 (10%) Query: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133 + + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P Sbjct: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131 Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190 +ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK Sbjct: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187 Query: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248 G++E +E + TV S+ L +E + C V + + L VQY+P+ Sbjct: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244 Query: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303 V I+ + LQ + ++LTC+A P W ++ +P+ LF Sbjct: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301 Query: 304 GPINYSLAGTYICEATNPIG 323 +N + GTY CEA+N +G Sbjct: 302 N-LNKTDNGTYRCEASNIVG 320 >gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] Length = 398 Score = 70.5 bits (171), Expect = 2e-12 Identities = 73/248 (29%), Positives = 108/248 (43%), Gaps = 23/248 (9%) Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154 R++ + + + +I +S + L DEG Y C T P +S + L + KP I G + Sbjct: 82 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 139 Query: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209 + LR K C S+ KP + ++W + L GE QE +PNG T TV S Sbjct: 140 SSLREK-----DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 192 Query: 210 RYRLVPSREAHQQSLACIVNYH----MDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDV 265 +RE S+ C VN+ DR S + V Y P I D + + Sbjct: 193 SVTFQVTREDDGASIVCSVNHESLKGADR-STSQRIEVLYTPTAMIRP-DPPHPREGQKL 250 Query: 266 KLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325 L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+ Sbjct: 251 LLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSY 308 Query: 326 SGQVEVNI 333 +N+ Sbjct: 309 KAYYTLNV 316 >gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] Length = 432 Score = 70.5 bits (171), Expect = 2e-12 Identities = 73/248 (29%), Positives = 108/248 (43%), Gaps = 23/248 (9%) Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154 R++ + + + +I +S + L DEG Y C T P +S + L + KP I G + Sbjct: 116 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 173 Query: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209 + LR K C S+ KP + ++W + L GE QE +PNG T TV S Sbjct: 174 SSLREK-----DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 226 Query: 210 RYRLVPSREAHQQSLACIVNYH----MDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDV 265 +RE S+ C VN+ DR S + V Y P I D + + Sbjct: 227 SVTFQVTREDDGASIVCSVNHESLKGADR-STSQRIEVLYTPTAMIRP-DPPHPREGQKL 284 Query: 266 KLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325 L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+ Sbjct: 285 LLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSY 342 Query: 326 SGQVEVNI 333 +N+ Sbjct: 343 KAYYTLNV 350 >gi|90903245 CD200 antigen isoform b [Homo sapiens] Length = 294 Score = 68.9 bits (167), Expect = 6e-12 Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 14/185 (7%) Query: 45 TDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSF 104 T L CS N ++ VTWQK S +N+ ++ + GV + Y++++ + Sbjct: 70 TPASLKCSLQNAQEALI---VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGL 126 Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164 + TI + LEDEG Y+C F TF G LTV +P L K +D Sbjct: 127 QNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPI-------VSLHYKFSED 179 Query: 165 DKVLVATCTSANGKPPSVVSWETRLKG-EAEYQEIRNPNGTVTVISRYRLVPSREAHQQS 223 L TC SA +P +V W+ G E + +PNGT +V S + + + Sbjct: 180 H--LNITC-SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKE 236 Query: 224 LACIV 228 + C V Sbjct: 237 VICQV 241 >gi|90903247 CD200 antigen isoform a precursor [Homo sapiens] Length = 269 Score = 68.9 bits (167), Expect = 6e-12 Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 14/185 (7%) Query: 45 TDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSF 104 T L CS N ++ VTWQK S +N+ ++ + GV + Y++++ + Sbjct: 45 TPASLKCSLQNAQEALI---VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGL 101 Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164 + TI + LEDEG Y+C F TF G LTV +P L K +D Sbjct: 102 QNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPI-------VSLHYKFSED 154 Query: 165 DKVLVATCTSANGKPPSVVSWETRLKG-EAEYQEIRNPNGTVTVISRYRLVPSREAHQQS 223 L TC SA +P +V W+ G E + +PNGT +V S + + + Sbjct: 155 H--LNITC-SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKE 211 Query: 224 LACIV 228 + C V Sbjct: 212 VICQV 216 >gi|21686977 cell adhesion molecule 4 [Homo sapiens] Length = 388 Score = 66.6 bits (161), Expect = 3e-11 Identities = 75/261 (28%), Positives = 108/261 (41%), Gaps = 31/261 (11%) Query: 78 VAIYNPSM------GVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPT 131 V I NP+ G L R ++E P IRLS LEDEG Y C+ T T Sbjct: 54 VVIQNPARQTLFFNGTRALKDERFQLEEFSPRRV--RIRLSDARLEDEGGYFCQLYTEDT 111 Query: 132 GNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETR 188 ++ + LTV+ P N + + +A +G + ++ +C +P + + W Sbjct: 112 HHQIA--TLTVLVAPENPVVEVRE--QAVEGGEVEL---SCLVPRSRPAATLRWYRDRKE 164 Query: 189 LKGEAEYQEIRNPNGTV-TVISRYRLVPSREAHQQSLACIVNYHM----DRFKESLTLNV 243 LKG + QE NG V +V S R R+ + C + L+V Sbjct: 165 LKGVSSSQE----NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDV 220 Query: 244 QYEPEVTIEGFDGNWYLQRMD-VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFF 302 QY P I ++ D + LTC NP + W N SLP+ EA TL Sbjct: 221 QYSPTARIHASQA--VVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTL 278 Query: 303 KGPINYSLAGTYICEATNPIG 323 G ++ GTY CEA+N G Sbjct: 279 PGLVSAD-NGTYTCEASNKHG 298 >gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] Length = 437 Score = 64.3 bits (155), Expect = 2e-10 Identities = 63/243 (25%), Positives = 100/243 (41%), Gaps = 20/243 (8%) Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 R+E +R S+ + +I +S + L DEG Y C T P + S+ LTV+ P E Q Sbjct: 78 RIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPV--KTSKAYLTVLGVP----EKPQI 131 Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGEAEYQEIRNPNGTVTVISRYR 212 + + ++ TC ++ KP + + W + +K +E T TV S Sbjct: 132 SGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLD 191 Query: 213 LVPSREAHQQSLACIVNYHMDRFKESL---TLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269 R ++ C V++ + L + Y P V I + + + LTC Sbjct: 192 FRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIP-STPFPQEGQPLILTC 250 Query: 270 KADANPPATEYHWTTLNGSLPKG----VEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325 ++ P WT G LP V + + F +N + GTY CEATN IG Sbjct: 251 ESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF---LNKTDNGTYRCEATNTIGQS 307 Query: 326 SGQ 328 S + Sbjct: 308 SAE 310 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 62.4 bits (150), Expect = 6e-10 Identities = 74/309 (23%), Positives = 124/309 (40%), Gaps = 40/309 (12%) Query: 47 VVLHCSFANPLPSVKITQVTWQKS-----TNGSKQNVAIYNPSMGVSVLAPYRERVEFLR 101 V + S P+P+ + Q + ++ T G ++ P + + Y+ Sbjct: 2908 VTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPA 2967 Query: 102 PSFTDGT-IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA- 159 T G+ +RL + D G Y+C A+ P +E+ +TV EG+ LR+ Sbjct: 2968 RHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPS-----EGSSYRLRSP 3022 Query: 160 -----------KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVI 208 ++GQD C +G P + W+TR + E E +PNG++ I Sbjct: 3023 VISIDPPSSTVQQGQDASF---KCLIHDGAAPISLEWKTRNQ-ELEDNVHISPNGSIITI 3078 Query: 209 SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLT 268 V +R ++ + C+ + + + L+V P V++ W V L Sbjct: 3079 -----VGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLE 3133 Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPI------NYSLAGTYICEATNPI 322 C A P + WT ++ S P +E + L + S AGTY+C A N + Sbjct: 3134 C-VSAGEPRSSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191 Query: 323 GTRSGQVEV 331 GT QVEV Sbjct: 3192 GTAQKQVEV 3200 Score = 50.1 bits (118), Expect = 3e-06 Identities = 58/241 (24%), Positives = 92/241 (38%), Gaps = 32/241 (13%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTV----MAKPTNWIEGTQAVLRAKKGQD 164 +++S + D G Y+C A G + Q+ + V MA ++ +A L + G Sbjct: 3170 LQISSAKPSDAGTYVC-LAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGH- 3227 Query: 165 DKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQS- 223 C SA G P + W ++R+P + L+ R A Q S Sbjct: 3228 --TATLRC-SATGSPAPTIHWS----------KLRSPLPWQHRLEGDTLIIPRVAQQDSG 3274 Query: 224 -LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHW 282 C + ++ L+V+ P T + V+L C A PP T + W Sbjct: 3275 QYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGET-VQLQCLAHGTPPLT-FQW 3332 Query: 283 TTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAFCQLIYP 342 + + SLP A+N L F+ +G Y C TN +G+ AF QL+ Sbjct: 3333 SRVGSSLPGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAE--------AFAQLLVQ 3383 Query: 343 G 343 G Sbjct: 3384 G 3384 Score = 50.1 bits (118), Expect = 3e-06 Identities = 79/331 (23%), Positives = 124/331 (37%), Gaps = 68/331 (20%) Query: 20 LTAFFLPGVHSQVVQVNDSMYG-FIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNV 78 L A +P + VQV + IG V HC+ +PS + TQ+ W K Sbjct: 3389 LPATSIPAGSTPTVQVTPQLETKSIGASVEFHCA----VPSDRGTQLRWFKEGGQ----- 3439 Query: 79 AIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQL 138 L P S DG +R+ L+ +G YIC+ A P G ++ Sbjct: 3440 -----------LPPGH--------SVQDGVLRIQNLDQSCQGTYICQ-AHGPWGKAQASA 3479 Query: 139 NLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEI 198 L + A P+ I +V G V A G P V+W +++ G + Sbjct: 3480 QLVIQALPSVLINIRTSVQTVVVGH----AVEFECLALGDPKPQVTW-SKVGGHLRPGIV 3534 Query: 199 RNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNW 258 ++ G V I+ L + + C + + L VQ P++++ Sbjct: 3535 QS--GGVVRIAHVELADAGQYR-----CTATNAAGTTQSHVLLLVQALPQISMP------ 3581 Query: 259 YLQRMDVKLTCKADA-------NPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA 311 +V++ + A P + W+ L+GSLP +N L + A Sbjct: 3582 ----QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPS-VRPQDA 3636 Query: 312 GTYICEATNPIGTRSGQVEVNITAFCQLIYP 342 GTY+C ATN R G+V+ AF L P Sbjct: 3637 GTYVCTATN----RQGKVK----AFAHLQVP 3659 Score = 42.4 bits (98), Expect = 6e-04 Identities = 60/239 (25%), Positives = 91/239 (38%), Gaps = 33/239 (13%) Query: 106 DGTIRLSRLELEDEGVYICEFATF-----PTGNRESQLNLTVMAKPTNWIEGTQAVLRAK 160 +G + + ++L D G Y+C + T Q + T+ A P I Q L + Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSA-PVVSIHPPQ--LTVQ 1878 Query: 161 KGQDDKVLVATCTSANGKPPSVVSW------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214 GQ L SA G P + W + K + +R P T ++Y Sbjct: 1879 PGQ----LAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCR 1934 Query: 215 PSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADAN 274 A QQ +++ H VQ PE T + G V+L C+A Sbjct: 1935 AHSSAGQQVARAVLHVHGGGGPR-----VQVSPERT-QVHAGR------TVRLYCRAAGV 1982 Query: 275 PPATEYHWTTLNGSLPKGVEAQNRTL--FFKGPINYSLAGTYICEATNPIGTRSGQVEV 331 P AT W GSLP ++ + I + AG Y+C AT+P GT +++V Sbjct: 1983 PSAT-ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQV 2040 Score = 38.5 bits (88), Expect = 0.009 Identities = 26/80 (32%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 264 DVKLTCKADANPPATEYHWTTL-NGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPI 322 DV C A + PA WT L NG LP N L + + S AGTY+C +N Sbjct: 1788 DVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRN-VQLSDAGTYVCTGSNMF 1846 Query: 323 GTRSGQVEVNITAFCQLIYP 342 G +++ A L P Sbjct: 1847 AMDQGTATLHVQASGTLSAP 1866 Score = 36.6 bits (83), Expect = 0.035 Identities = 52/229 (22%), Positives = 88/229 (38%), Gaps = 31/229 (13%) Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177 + G Y C A+ G +S +NL+V PT + + + K G K + C SA G Sbjct: 3085 NHGTYRC-VASNAYGVAQSVVNLSVHGPPTVSVL-PEGPVWVKVG---KAVTLECVSA-G 3138 Query: 178 KPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKE 237 +P S W TR+ E R G + + ++ ++ + + C+ + ++ Sbjct: 3139 EPRSSARW-TRISSTPAKLEQRT-YGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK 3196 Query: 238 SLTLNVQY-------------EPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTT 284 + + V E E+T+E L C A +P T HW+ Sbjct: 3197 QVEVIVDTGAMAPGAPQVQAEEAELTVEAGH--------TATLRCSATGSPAPT-IHWSK 3247 Query: 285 LNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 L LP + TL +G YIC AT+P G + +++ Sbjct: 3248 LRSPLPWQHRLEGDTLIIPRVAQQD-SGQYICNATSPAGHAEATIILHV 3295 Score = 32.7 bits (73), Expect = 0.50 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 265 VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGT 324 V+ C A P + W+ + G L G+ Q+ + + + AG Y C ATN GT Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVGGHLRPGI-VQSGGVVRIAHVELADAGQYRCTATNAAGT 3563 Query: 325 RSGQVEVNITAFCQLIYPGKGRTRA 349 V + + A Q+ P + R A Sbjct: 3564 TQSHVLLLVQALPQISMPQEVRVPA 3588 Score = 32.3 bits (72), Expect = 0.66 Identities = 52/246 (21%), Positives = 89/246 (36%), Gaps = 39/246 (15%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTV-----------MAKPTNWIEGTQAVL 157 +RL ++ D G Y+C +G +E+ + +T+ +A P IE + A L Sbjct: 2488 LRLLQVTPADSGEYVCRVVG-SSGTQEASVLVTIQQRLSGSHSQGVAYPVR-IESSSASL 2545 Query: 158 RAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSR 217 D LVA+ + P ++W R +I V SR R+ Sbjct: 2546 ANGHTLDLNCLVAS------QAPHTITWYKRGGSLPSRHQI--------VGSRLRIPQVT 2591 Query: 218 EAHQQSLACIVNYHMDRFKESLTLNVQ---------YEPEVTIEGFDGNWYLQRMDVKLT 268 A C V+ + SL + +Q P + IE ++ + L Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT-VVEGQTLDLN 2650 Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328 C P A W GSLP + L ++ + +G Y+C A N I Sbjct: 2651 CVVARQPQAI-ITWYKRGGSLPSRHQTHGSHLRLH-QMSVADSGEYVCRANNNIDALEAS 2708 Query: 329 VEVNIT 334 + ++++ Sbjct: 2709 IVISVS 2714 >gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] Length = 600 Score = 59.7 bits (143), Expect = 4e-09 Identities = 54/225 (24%), Positives = 95/225 (42%), Gaps = 23/225 (10%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ R EL+D+ VY C+ R LTV+ P + + V+ + G L Sbjct: 112 LKILRAELQDDAVYECQ--AIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDP---L 166 Query: 169 VATCTSANGKPPSVVSWETR---LKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225 TC + N KP + + W + + G + + +++S + P + QS+ Sbjct: 167 NLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIV 226 Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283 C N + KE S+T+++Q+ P V + + L+ V C A ANP T+Y W Sbjct: 227 CRATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWA 285 Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGT 324 + + RT +F P++ CE TN +G+ Sbjct: 286 KRGQIIKEASGEVYRTTVDYTYFSEPVS--------CEVTNALGS 322 Score = 38.9 bits (89), Expect = 0.007 Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 13/114 (11%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T+ L + ED G Y+C G E ++ LTV P TQ L +KGQ Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQ---- 437 Query: 168 LVATCTSANGKPPSVVSW-------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214 C + PP ++W E+ G + I G ++ ++ +V Sbjct: 438 --IKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489 >gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] Length = 778 Score = 59.7 bits (143), Expect = 4e-09 Identities = 54/225 (24%), Positives = 95/225 (42%), Gaps = 23/225 (10%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ R EL+D+ VY C+ R LTV+ P + + V+ + G L Sbjct: 112 LKILRAELQDDAVYECQ--AIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDP---L 166 Query: 169 VATCTSANGKPPSVVSWETR---LKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225 TC + N KP + + W + + G + + +++S + P + QS+ Sbjct: 167 NLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIV 226 Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283 C N + KE S+T+++Q+ P V + + L+ V C A ANP T+Y W Sbjct: 227 CRATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWA 285 Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGT 324 + + RT +F P++ CE TN +G+ Sbjct: 286 KRGQIIKEASGEVYRTTVDYTYFSEPVS--------CEVTNALGS 322 Score = 38.9 bits (89), Expect = 0.007 Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 13/114 (11%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T+ L + ED G Y+C G E ++ LTV P TQ L +KGQ Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQ---- 437 Query: 168 LVATCTSANGKPPSVVSW-------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214 C + PP ++W E+ G + I G ++ ++ +V Sbjct: 438 --IKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489 >gi|126517478 peroxidasin homolog-like [Homo sapiens] Length = 1463 Score = 59.7 bits (143), Expect = 4e-09 Identities = 65/243 (26%), Positives = 103/243 (42%), Gaps = 35/243 (14%) Query: 104 FTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNL----TVMAKPTNWIEGTQAVLRA 159 F DGT+ + D+GVY C A G ++Q + ++ AKP+ I+ Sbjct: 285 FDDGTLMIRNTRESDQGVYQC-MARNSAGEAKTQSAMLRYSSLPAKPSFVIQ-------- 335 Query: 160 KKGQDDKVLVATCTS----ANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVP 215 QD +VL+ T T+ A G P +++W TR G E+ T Y Sbjct: 336 --PQDTEVLIGTSTTLECMATGHPHPLITW-TRDNG----LELDGSRHVATSSGLYLQNI 388 Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANP 275 ++ H + C N + + + VQ P+ T+ D L+ V+ C+AD NP Sbjct: 389 TQRDHGR-FTCHANNSHGTVQAAANIIVQAPPQFTVTPKD-QVVLEEHAVEWLCEADGNP 446 Query: 276 PATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYICEATNPIGTRSGQVE 330 P WT G LP VE Q+ T+ G + A G Y C+A + +G + V+ Sbjct: 447 PPV-IVWTKTGGQLP--VEGQH-TVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQ 502 Query: 331 VNI 333 + + Sbjct: 503 LTV 505 Score = 30.4 bits (67), Expect = 2.5 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 12/121 (9%) Query: 65 VTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYIC 124 V W +G+ V ++ + G + VE + GT+R+ R D+G Y C Sbjct: 436 VEWLCEADGNPPPVIVWTKTGG-------QLPVEGQHTVLSSGTLRIDRAAQHDQGQYEC 488 Query: 125 EFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVS 184 + A G ++ + LTV K + G++ + +C A G+P +++ Sbjct: 489 Q-AVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINI---SC-HAQGEPQPIIT 543 Query: 185 W 185 W Sbjct: 544 W 544 >gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3874 Score = 56.2 bits (134), Expect = 4e-08 Identities = 62/231 (26%), Positives = 94/231 (40%), Gaps = 17/231 (7%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 ++L R + D GVY C+ A+ G E L V PT IEG K + + Sbjct: 367 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 423 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227 C A G P +SW AE E R +G+V RL EA +C+ Sbjct: 424 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 477 Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + ++ VQ P++ + EG + ++L C+A +P T W N Sbjct: 478 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 535 Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 G + GV+ A T + +G + C+ATN GT +VEV++ Sbjct: 536 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586 Score = 51.6 bits (122), Expect = 1e-06 Identities = 57/232 (24%), Positives = 91/232 (39%), Gaps = 19/232 (8%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 + + ++ D+G+Y C+ + G LTV PT T+ V + L Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 1951 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228 V TC +G P V+W LK E +G V+ R +L + A + C+ Sbjct: 1952 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 2006 Query: 229 NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287 ++ + V P + G + L+ +V+L C+AD PP + W Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLKDGS 2065 Query: 288 SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 L + + R +L KG + S AG Y C A NP G + VN+ Sbjct: 2066 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNV 2116 Score = 43.9 bits (102), Expect = 2e-04 Identities = 80/312 (25%), Positives = 114/312 (36%), Gaps = 52/312 (16%) Query: 41 GFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFL 100 G G DV L C + V QV W K +Q V P + V Sbjct: 229 GLAGADVELQCWTSG----VPTPQVEWTKD----RQPVLPGGPHLQVQ------------ 268 Query: 101 RPSFTDGTI-RLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA 159 DG + R++ + DEG Y C A P G + L V A PT W G+ Sbjct: 269 ----EDGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIW--GSNETGEV 321 Query: 160 KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISR----YRLVP 215 +D LV A G P ++W K A P T V +R +L Sbjct: 322 AVMEDH--LVQLLCEARGVPTPNITW---FKDGALL-----PTSTKVVYTRGGRQLQLGR 371 Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM----DVKLTCKA 271 ++ + C + + +++ L+V P TIEG G Y+ + V L C A Sbjct: 372 AQSSDAGVYTCKASNAVGAAEKATRLDVYVPP--TIEGAGGRPYVVKAVAGRPVALECVA 429 Query: 272 DANP-PATEYHWTTLN--GSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328 +P P +H L S +E L + P S +G Y C A++P G Q Sbjct: 430 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS-SGLYSCVASSPAGEAVLQ 488 Query: 329 VEVNITAFCQLI 340 V + QL+ Sbjct: 489 YSVEVQVPPQLL 500 Score = 41.6 bits (96), Expect = 0.001 Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 25/224 (11%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ +++L DEG+Y C AT G + ++ L V+ P N G K + Sbjct: 659 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 711 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226 V A+G PP VSW KG +Q + + G TV+V R R+ ++ + S C Sbjct: 712 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 765 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + + + L V P +T+ L V+LTC A P T N Sbjct: 766 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 825 Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIG 323 P G F G +LA G Y C A + +G Sbjct: 826 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVG 866 Score = 38.5 bits (88), Expect = 0.009 Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 12/141 (8%) Query: 111 LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170 L + +L EG Y CE + GN L L V P I G + D V Sbjct: 1031 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 1087 Query: 171 TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228 C +A GKPP V+WE + G +++N ++ V ++ AH +C+ Sbjct: 1088 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 1140 Query: 229 NYHMDRFKESLTLNVQYEPEV 249 R + L+V PE+ Sbjct: 1141 ENLAGRAERKFELSVLVPPEL 1161 Score = 38.1 bits (87), Expect = 0.012 Identities = 69/296 (23%), Positives = 105/296 (35%), Gaps = 53/296 (17%) Query: 37 DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95 + + + + V L C A+P P +VTW K + S+G V Sbjct: 1754 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 1793 Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 FL P T++L R L D G+Y CE A G + + L+V+ P A Sbjct: 1794 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 1839 Query: 156 VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209 +A +G D VLV A + P V+W + Q + G Sbjct: 1840 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 1895 Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269 R + ++ + + +C V+ + TL VQ P + + + LTC Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1955 Query: 270 KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATN 320 P T T L +P A + + G + S AGTY C A N Sbjct: 1956 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 2008 Score = 37.4 bits (85), Expect = 0.020 Identities = 50/229 (21%), Positives = 85/229 (37%), Gaps = 36/229 (15%) Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158 G +R++ ED G Y+C A G+ + L V P + EG+ A L Sbjct: 2809 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2867 Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218 K A G P ++W+ + Q + G T+ L+ Sbjct: 2868 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 2907 Query: 219 AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275 Q + C + R + + L + P T G+ L+ D + L C A +P Sbjct: 2908 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 2965 Query: 276 PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIG 323 WT + + +GV Q+ + + ++ +GTY+C A N +G Sbjct: 2966 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013 Score = 34.3 bits (77), Expect = 0.17 Identities = 52/232 (22%), Positives = 83/232 (35%), Gaps = 21/232 (9%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +R+ + +L D G Y C A+ G+ E + L V P + VL Sbjct: 750 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 799 Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223 V T +A G P + W LK P V R L +R + Sbjct: 800 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 856 Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283 +C+ + ++ + L V P + E + + + V L C++ A PP W Sbjct: 857 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 915 Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 P+ GV + ++ L + AG Y CEA N G +N+ Sbjct: 916 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967 Score = 34.3 bits (77), Expect = 0.17 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 15/83 (18%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T+R+S+++L D G++ C A P G + L V P VL + Q+D V Sbjct: 2177 TLRISKVQLADAGIFTC-VAASPAGVADRNFTLQVQVPP---------VLEPVEFQNDVV 2226 Query: 168 -----LVATCTSANGKPPSVVSW 185 LV A G P +VSW Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSW 2249 Score = 33.9 bits (76), Expect = 0.23 Identities = 57/264 (21%), Positives = 88/264 (33%), Gaps = 48/264 (18%) Query: 90 LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149 L P R E L +G++R+ + +D G Y+C A+ G+ +L V+ P Sbjct: 2522 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 2576 Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209 + L A + C ++ P VV W+ K + Q+ Sbjct: 2577 PSPSNLTLTA-----HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 2620 Query: 210 RYRLVPSR--------EAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261 YRL+PS C+V+ + + V P + + D Sbjct: 2621 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT-VTM 2679 Query: 262 RMDVKLTCKADANPPATEYHWTTLNGSL----------PKGVEAQNRTLFFKGPINYSLA 311 V LTC + PA W+ L P G + L PI+ A Sbjct: 2680 MAPVVLTCHS-TGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQAL----PIH---A 2731 Query: 312 GTYICEATNPIGTRSGQVEVNITA 335 G Y C A N G V + + A Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQA 2755 Score = 32.0 bits (71), Expect = 0.86 Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 15/230 (6%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ + E+ G Y C+ A+ G L V+ P I G L + + Sbjct: 1615 LQIPLVRAENAGRYSCK-ASNEVGEDWLHYELLVLTPPV--ILGDTEELVEEVTVNASST 1671 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE-AHQQSLACI 227 V+ A G P +SW L+ + +P V + V + E A S C+ Sbjct: 1672 VSLQCPALGNPVPTISW---LQNGLPFSP--SPRLQVLEDGQVLQVSTAEVADAASYMCV 1726 Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNG 287 ++ TL VQ P + + + V L C A+P E W + Sbjct: 1727 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQ 1785 Query: 288 SLPKGVEA----QNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 +L G E TL G S +G Y CEA N G V++++ Sbjct: 1786 ALSLGEEVFLLPGTHTLQL-GRARLSDSGMYTCEALNAAGRDQKLVQLSV 1834 Score = 30.4 bits (67), Expect = 2.5 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%) Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 R LR +G++ + R E +D G Y C A G + + L + + P +E Sbjct: 3069 RGSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 3127 Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185 +R+ G D VA A G+P + W Sbjct: 3128 TVRS--GDD----VALRCQATGEPTPTIEW 3151 Score = 30.0 bits (66), Expect = 3.3 Identities = 51/226 (22%), Positives = 83/226 (36%), Gaps = 21/226 (9%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T++ + + ED G Y+C +A G ++ + V P E ++ G Sbjct: 2990 TLQRAAVSREDSGTYVC-WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS---- 3044 Query: 168 LVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226 + C G P + W + L + + NG++T+ R R C Sbjct: 3045 IQLDCV-VRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGR------YQC 3097 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + M K+ + L +Q P +E D DV L C+A P T W L Sbjct: 3098 LAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDDVALRCQATGEPTPT-IEW--LQ 3153 Query: 287 GSLPKGVEAQNRTL----FFKGPINYSLAGTYICEATNPIGTRSGQ 328 P + RTL + + AGTY C A N +G+ + + Sbjct: 3154 AGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATAR 3199 >gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] Length = 5065 Score = 56.2 bits (134), Expect = 4e-08 Identities = 62/231 (26%), Positives = 94/231 (40%), Gaps = 17/231 (7%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 ++L R + D GVY C+ A+ G E L V PT IEG K + + Sbjct: 1558 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 1614 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227 C A G P +SW AE E R +G+V RL EA +C+ Sbjct: 1615 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 1668 Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + ++ VQ P++ + EG + ++L C+A +P T W N Sbjct: 1669 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 1726 Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 G + GV+ A T + +G + C+ATN GT +VEV++ Sbjct: 1727 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777 Score = 51.6 bits (122), Expect = 1e-06 Identities = 57/232 (24%), Positives = 91/232 (39%), Gaps = 19/232 (8%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 + + ++ D+G+Y C+ + G LTV PT T+ V + L Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 3142 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228 V TC +G P V+W LK E +G V+ R +L + A + C+ Sbjct: 3143 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 3197 Query: 229 NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287 ++ + V P + G + L+ +V+L C+AD PP + W Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLKDGS 3256 Query: 288 SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 L + + R +L KG + S AG Y C A NP G + VN+ Sbjct: 3257 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNV 3307 Score = 43.9 bits (102), Expect = 2e-04 Identities = 80/312 (25%), Positives = 114/312 (36%), Gaps = 52/312 (16%) Query: 41 GFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFL 100 G G DV L C + V QV W K +Q V P + V Sbjct: 1420 GLAGADVELQCWTSG----VPTPQVEWTKD----RQPVLPGGPHLQVQ------------ 1459 Query: 101 RPSFTDGTI-RLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA 159 DG + R++ + DEG Y C A P G + L V A PT W G+ Sbjct: 1460 ----EDGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIW--GSNETGEV 1512 Query: 160 KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISR----YRLVP 215 +D LV A G P ++W K A P T V +R +L Sbjct: 1513 AVMEDH--LVQLLCEARGVPTPNITW---FKDGALL-----PTSTKVVYTRGGRQLQLGR 1562 Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM----DVKLTCKA 271 ++ + C + + +++ L+V P TIEG G Y+ + V L C A Sbjct: 1563 AQSSDAGVYTCKASNAVGAAEKATRLDVYVPP--TIEGAGGRPYVVKAVAGRPVALECVA 1620 Query: 272 DANP-PATEYHWTTLN--GSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328 +P P +H L S +E L + P S +G Y C A++P G Q Sbjct: 1621 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS-SGLYSCVASSPAGEAVLQ 1679 Query: 329 VEVNITAFCQLI 340 V + QL+ Sbjct: 1680 YSVEVQVPPQLL 1691 Score = 41.6 bits (96), Expect = 0.001 Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 25/224 (11%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ +++L DEG+Y C AT G + ++ L V+ P N G K + Sbjct: 1850 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 1902 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226 V A+G PP VSW KG +Q + + G TV+V R R+ ++ + S C Sbjct: 1903 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 1956 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + + + L V P +T+ L V+LTC A P T N Sbjct: 1957 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 2016 Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIG 323 P G F G +LA G Y C A + +G Sbjct: 2017 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVG 2057 Score = 38.5 bits (88), Expect = 0.009 Identities = 53/232 (22%), Positives = 96/232 (41%), Gaps = 27/232 (11%) Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDK 166 G++RL+++++ D G Y C A+ P G+ + L V P ++ VL+ G+ Sbjct: 1082 GSLRLAQVQVGDSGHYECT-ASNPAGSASHRYVLGVQVPPQ--VQPGPRVLKVLVGE--- 1135 Query: 167 VLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226 L C A G P +SW + + R P G+V + + + +A + Sbjct: 1136 ALDLNCV-AEGNPEPQLSWSK----DGVVLQGRGPQGSV----HFAAIRTSDAGRYRCEA 1186 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANPPATEYHWT 283 + +D ++ + L V P + G L+R+ + L C A P + W Sbjct: 1187 SNSAGVDAWE--VELRVLEPPHWGADETSG--LLERVAGENASLPCPARGTPKP-QVTWR 1241 Query: 284 TLNGSLP----KGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEV 331 S P GV F ++ + +G Y C+ATN +G+ S + ++ Sbjct: 1242 KGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKL 1293 Score = 38.5 bits (88), Expect = 0.009 Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 12/141 (8%) Query: 111 LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170 L + +L EG Y CE + GN L L V P I G + D V Sbjct: 2222 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 2278 Query: 171 TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228 C +A GKPP V+WE + G +++N ++ V ++ AH +C+ Sbjct: 2279 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 2331 Query: 229 NYHMDRFKESLTLNVQYEPEV 249 R + L+V PE+ Sbjct: 2332 ENLAGRAERKFELSVLVPPEL 2352 Score = 38.1 bits (87), Expect = 0.012 Identities = 69/296 (23%), Positives = 105/296 (35%), Gaps = 53/296 (17%) Query: 37 DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95 + + + + V L C A+P P +VTW K + S+G V Sbjct: 2945 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 2984 Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 FL P T++L R L D G+Y CE A G + + L+V+ P A Sbjct: 2985 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 3030 Query: 156 VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209 +A +G D VLV A + P V+W + Q + G Sbjct: 3031 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 3086 Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269 R + ++ + + +C V+ + TL VQ P + + + LTC Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 3146 Query: 270 KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATN 320 P T T L +P A + + G + S AGTY C A N Sbjct: 3147 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199 Score = 37.7 bits (86), Expect = 0.016 Identities = 53/217 (24%), Positives = 85/217 (39%), Gaps = 45/217 (20%) Query: 151 EGTQ---AVLRAKKGQDDKVLVAT--------CTSANGKPPSVVSWETRLKGEAEYQEIR 199 EGT AV RA G+ +V T + P R+ GEA Y Sbjct: 491 EGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYN--- 547 Query: 200 NPNGTVTVISRYRLVPSREAHQQSLA------------------CIVNYHMDRFKESLTL 241 +T + +R++P+ LA C+ + + S+ L Sbjct: 548 -----LTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWL 602 Query: 242 NVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG----VEAQN 297 V+ P+V+I + Q ++VK++C A P W+ + +L + V+AQ Sbjct: 603 LVREAPQVSIHT-SSQHFSQGVEVKVSCSASGYP-TPHISWSRESQALQEDSRIHVDAQG 660 Query: 298 RTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334 TL +G + AG Y C+ATN +GT V + T Sbjct: 661 -TLIIQG-VAPEDAGNYSCQATNEVGTDQETVTLYYT 695 Score = 37.4 bits (85), Expect = 0.020 Identities = 50/229 (21%), Positives = 85/229 (37%), Gaps = 36/229 (15%) Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158 G +R++ ED G Y+C A G+ + L V P + EG+ A L Sbjct: 4000 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 4058 Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218 K A G P ++W+ + Q + G T+ L+ Sbjct: 4059 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 4098 Query: 219 AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275 Q + C + R + + L + P T G+ L+ D + L C A +P Sbjct: 4099 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 4156 Query: 276 PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIG 323 WT + + +GV Q+ + + ++ +GTY+C A N +G Sbjct: 4157 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204 Score = 34.3 bits (77), Expect = 0.17 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 15/83 (18%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T+R+S+++L D G++ C A P G + L V P VL + Q+D V Sbjct: 3368 TLRISKVQLADAGIFTC-VAASPAGVADRNFTLQVQVPP---------VLEPVEFQNDVV 3417 Query: 168 -----LVATCTSANGKPPSVVSW 185 LV A G P +VSW Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSW 3440 Score = 33.9 bits (76), Expect = 0.23 Identities = 52/232 (22%), Positives = 83/232 (35%), Gaps = 21/232 (9%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +R+ + +L D G Y C A+ G+ E + L V P + VL Sbjct: 1941 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 1990 Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223 V T +A G P + W LK P V R L +R + Sbjct: 1991 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 2047 Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283 +C+ + ++ + L V P + E + + + V L C++ A PP W Sbjct: 2048 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 2106 Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 P+ GV + ++ L + AG Y CEA N G +N+ Sbjct: 2107 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 2158 Score = 33.9 bits (76), Expect = 0.23 Identities = 57/264 (21%), Positives = 88/264 (33%), Gaps = 48/264 (18%) Query: 90 LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149 L P R E L +G++R+ + +D G Y+C A+ G+ +L V+ P Sbjct: 3713 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 3767 Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209 + L A + C ++ P VV W+ K + Q+ Sbjct: 3768 PSPSNLTLTA-----HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 3811 Query: 210 RYRLVPSR--------EAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261 YRL+PS C+V+ + + V P + + D Sbjct: 3812 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT-VTM 3870 Query: 262 RMDVKLTCKADANPPATEYHWTTLNGSL----------PKGVEAQNRTLFFKGPINYSLA 311 V LTC + PA W+ L P G + L PI+ A Sbjct: 3871 MAPVVLTCHS-TGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQAL----PIH---A 3922 Query: 312 GTYICEATNPIGTRSGQVEVNITA 335 G Y C A N G V + + A Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQA 3946 Score = 32.3 bits (72), Expect = 0.66 Identities = 53/241 (21%), Positives = 87/241 (36%), Gaps = 36/241 (14%) Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDK 166 G + + ED+ Y+CE A G +++ L V I + +R +GQ Sbjct: 845 GVLFFESVAPEDQAPYVCE-ARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVS 903 Query: 167 VLVATCTSANGKPPSVVSW--ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSL 224 + C G+P W + R IR +G++ L + + H Sbjct: 904 L---PCIVLAGRPLPERHWLKDGRPLPPGSRHSIR-ADGSL------HLDRALQEHAGRY 953 Query: 225 ACIVNYHMDRFKESLTLNVQYEPEV--------TIEGFDGNWYLQRMDVKLTCKADANPP 276 +C+ + L VQ P + T EG + L C A + P Sbjct: 954 SCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEG---------VPASLPCVA-SGVP 1003 Query: 277 ATEYHWTTLNGSL----PKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332 A WT +L P ++ TL P AG Y+C ATN +G S ++ ++ Sbjct: 1004 APTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTATNTVGFSSQEMRLS 1062 Query: 333 I 333 + Sbjct: 1063 V 1063 Score = 32.0 bits (71), Expect = 0.86 Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 15/230 (6%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ + E+ G Y C+ A+ G L V+ P I G L + + Sbjct: 2806 LQIPLVRAENAGRYSCK-ASNEVGEDWLHYELLVLTPPV--ILGDTEELVEEVTVNASST 2862 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE-AHQQSLACI 227 V+ A G P +SW L+ + +P V + V + E A S C+ Sbjct: 2863 VSLQCPALGNPVPTISW---LQNGLPFSP--SPRLQVLEDGQVLQVSTAEVADAASYMCV 2917 Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNG 287 ++ TL VQ P + + + V L C A+P E W + Sbjct: 2918 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQ 2976 Query: 288 SLPKGVEA----QNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 +L G E TL G S +G Y CEA N G V++++ Sbjct: 2977 ALSLGEEVFLLPGTHTLQL-GRARLSDSGMYTCEALNAAGRDQKLVQLSV 3025 Score = 30.8 bits (68), Expect = 1.9 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query: 267 LTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRS 326 L C A+ NP + W+ +G + +G Q F I S AG Y CEA+N G + Sbjct: 1139 LNCVAEGNPEP-QLSWSK-DGVVLQGRGPQGSVHF--AAIRTSDAGRYRCEASNSAGVDA 1194 Query: 327 GQVEVNI 333 +VE+ + Sbjct: 1195 WEVELRV 1201 Score = 30.4 bits (67), Expect = 2.5 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%) Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 R LR +G++ + R E +D G Y C A G + + L + + P +E Sbjct: 4260 RGSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 4318 Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185 +R+ G D VA A G+P + W Sbjct: 4319 TVRS--GDD----VALRCQATGEPTPTIEW 4342 Score = 30.0 bits (66), Expect = 3.3 Identities = 51/226 (22%), Positives = 83/226 (36%), Gaps = 21/226 (9%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T++ + + ED G Y+C +A G ++ + V P E ++ G Sbjct: 4181 TLQRAAVSREDSGTYVC-WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS---- 4235 Query: 168 LVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226 + C G P + W + L + + NG++T+ R R C Sbjct: 4236 IQLDCV-VRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGR------YQC 4288 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + M K+ + L +Q P +E D DV L C+A P T W L Sbjct: 4289 LAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDDVALRCQATGEPTPT-IEW--LQ 4344 Query: 287 GSLPKGVEAQNRTL----FFKGPINYSLAGTYICEATNPIGTRSGQ 328 P + RTL + + AGTY C A N +G+ + + Sbjct: 4345 AGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATAR 4390 >gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3783 Score = 56.2 bits (134), Expect = 4e-08 Identities = 62/231 (26%), Positives = 94/231 (40%), Gaps = 17/231 (7%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 ++L R + D GVY C+ A+ G E L V PT IEG K + + Sbjct: 276 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 332 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227 C A G P +SW AE E R +G+V RL EA +C+ Sbjct: 333 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 386 Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + ++ VQ P++ + EG + ++L C+A +P T W N Sbjct: 387 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 444 Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 G + GV+ A T + +G + C+ATN GT +VEV++ Sbjct: 445 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495 Score = 51.6 bits (122), Expect = 1e-06 Identities = 57/232 (24%), Positives = 91/232 (39%), Gaps = 19/232 (8%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 + + ++ D+G+Y C+ + G LTV PT T+ V + L Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 1860 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228 V TC +G P V+W LK E +G V+ R +L + A + C+ Sbjct: 1861 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 1915 Query: 229 NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287 ++ + V P + G + L+ +V+L C+AD PP + W Sbjct: 1916 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLKDGS 1974 Query: 288 SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 L + + R +L KG + S AG Y C A NP G + VN+ Sbjct: 1975 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNV 2025 Score = 43.9 bits (102), Expect = 2e-04 Identities = 80/312 (25%), Positives = 114/312 (36%), Gaps = 52/312 (16%) Query: 41 GFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFL 100 G G DV L C + V QV W K +Q V P + V Sbjct: 138 GLAGADVELQCWTSG----VPTPQVEWTKD----RQPVLPGGPHLQVQ------------ 177 Query: 101 RPSFTDGTI-RLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA 159 DG + R++ + DEG Y C A P G + L V A PT W G+ Sbjct: 178 ----EDGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIW--GSNETGEV 230 Query: 160 KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISR----YRLVP 215 +D LV A G P ++W K A P T V +R +L Sbjct: 231 AVMEDH--LVQLLCEARGVPTPNITW---FKDGALL-----PTSTKVVYTRGGRQLQLGR 280 Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM----DVKLTCKA 271 ++ + C + + +++ L+V P TIEG G Y+ + V L C A Sbjct: 281 AQSSDAGVYTCKASNAVGAAEKATRLDVYVPP--TIEGAGGRPYVVKAVAGRPVALECVA 338 Query: 272 DANP-PATEYHWTTLN--GSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328 +P P +H L S +E L + P S +G Y C A++P G Q Sbjct: 339 RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEAS-SGLYSCVASSPAGEAVLQ 397 Query: 329 VEVNITAFCQLI 340 V + QL+ Sbjct: 398 YSVEVQVPPQLL 409 Score = 41.6 bits (96), Expect = 0.001 Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 25/224 (11%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ +++L DEG+Y C AT G + ++ L V+ P N G K + Sbjct: 568 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 620 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226 V A+G PP VSW KG +Q + + G TV+V R R+ ++ + S C Sbjct: 621 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 674 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + + + L V P +T+ L V+LTC A P T N Sbjct: 675 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 734 Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIG 323 P G F G +LA G Y C A + +G Sbjct: 735 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVG 775 Score = 38.5 bits (88), Expect = 0.009 Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 12/141 (8%) Query: 111 LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170 L + +L EG Y CE + GN L L V P I G + D V Sbjct: 940 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 996 Query: 171 TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228 C +A GKPP V+WE + G +++N ++ V ++ AH +C+ Sbjct: 997 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 1049 Query: 229 NYHMDRFKESLTLNVQYEPEV 249 R + L+V PE+ Sbjct: 1050 ENLAGRAERKFELSVLVPPEL 1070 Score = 38.1 bits (87), Expect = 0.012 Identities = 69/296 (23%), Positives = 105/296 (35%), Gaps = 53/296 (17%) Query: 37 DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95 + + + + V L C A+P P +VTW K + S+G V Sbjct: 1663 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 1702 Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 FL P T++L R L D G+Y CE A G + + L+V+ P A Sbjct: 1703 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 1748 Query: 156 VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209 +A +G D VLV A + P V+W + Q + G Sbjct: 1749 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 1804 Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269 R + ++ + + +C V+ + TL VQ P + + + LTC Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1864 Query: 270 KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATN 320 P T T L +P A + + G + S AGTY C A N Sbjct: 1865 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917 Score = 37.4 bits (85), Expect = 0.020 Identities = 50/229 (21%), Positives = 85/229 (37%), Gaps = 36/229 (15%) Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158 G +R++ ED G Y+C A G+ + L V P + EG+ A L Sbjct: 2718 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2776 Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218 K A G P ++W+ + Q + G T+ L+ Sbjct: 2777 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 2816 Query: 219 AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275 Q + C + R + + L + P T G+ L+ D + L C A +P Sbjct: 2817 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 2874 Query: 276 PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIG 323 WT + + +GV Q+ + + ++ +GTY+C A N +G Sbjct: 2875 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922 Score = 34.3 bits (77), Expect = 0.17 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 15/83 (18%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T+R+S+++L D G++ C A P G + L V P VL + Q+D V Sbjct: 2086 TLRISKVQLADAGIFTC-VAASPAGVADRNFTLQVQVPP---------VLEPVEFQNDVV 2135 Query: 168 -----LVATCTSANGKPPSVVSW 185 LV A G P +VSW Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSW 2158 Score = 33.9 bits (76), Expect = 0.23 Identities = 52/232 (22%), Positives = 83/232 (35%), Gaps = 21/232 (9%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +R+ + +L D G Y C A+ G+ E + L V P + VL Sbjct: 659 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 708 Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223 V T +A G P + W LK P V R L +R + Sbjct: 709 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 765 Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283 +C+ + ++ + L V P + E + + + V L C++ A PP W Sbjct: 766 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 824 Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 P+ GV + ++ L + AG Y CEA N G +N+ Sbjct: 825 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 876 Score = 33.9 bits (76), Expect = 0.23 Identities = 57/264 (21%), Positives = 88/264 (33%), Gaps = 48/264 (18%) Query: 90 LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149 L P R E L +G++R+ + +D G Y+C A+ G+ +L V+ P Sbjct: 2431 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 2485 Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209 + L A + C ++ P VV W+ K + Q+ Sbjct: 2486 PSPSNLTLTA-----HTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 2529 Query: 210 RYRLVPSR--------EAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261 YRL+PS C+V+ + + V P + + D Sbjct: 2530 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT-VTM 2588 Query: 262 RMDVKLTCKADANPPATEYHWTTLNGSL----------PKGVEAQNRTLFFKGPINYSLA 311 V LTC + PA W+ L P G + L PI+ A Sbjct: 2589 MAPVVLTCHS-TGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQAL----PIH---A 2640 Query: 312 GTYICEATNPIGTRSGQVEVNITA 335 G Y C A N G V + + A Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQA 2664 Score = 32.0 bits (71), Expect = 0.86 Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 15/230 (6%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 +++ + E+ G Y C+ A+ G L V+ P I G L + + Sbjct: 1524 LQIPLVRAENAGRYSCK-ASNEVGEDWLHYELLVLTPPV--ILGDTEELVEEVTVNASST 1580 Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE-AHQQSLACI 227 V+ A G P +SW L+ + +P V + V + E A S C+ Sbjct: 1581 VSLQCPALGNPVPTISW---LQNGLPFSP--SPRLQVLEDGQVLQVSTAEVADAASYMCV 1635 Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNG 287 ++ TL VQ P + + + V L C A+P E W + Sbjct: 1636 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQ 1694 Query: 288 SLPKGVEA----QNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 +L G E TL G S +G Y CEA N G V++++ Sbjct: 1695 ALSLGEEVFLLPGTHTLQL-GRARLSDSGMYTCEALNAAGRDQKLVQLSV 1743 Score = 30.4 bits (67), Expect = 2.5 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%) Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155 R LR +G++ + R E +D G Y C A G + + L + + P +E Sbjct: 2978 RGSHLRHQLQNGSLTIRRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 3036 Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185 +R+ G D VA A G+P + W Sbjct: 3037 TVRS--GDD----VALRCQATGEPTPTIEW 3060 Score = 30.0 bits (66), Expect = 3.3 Identities = 51/226 (22%), Positives = 83/226 (36%), Gaps = 21/226 (9%) Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167 T++ + + ED G Y+C +A G ++ + V P E ++ G Sbjct: 2899 TLQRAAVSREDSGTYVC-WAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGS---- 2953 Query: 168 LVATCTSANGKPPSVVSW-ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226 + C G P + W + L + + NG++T+ R R C Sbjct: 2954 IQLDCV-VRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGR------YQC 3006 Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286 + M K+ + L +Q P +E D DV L C+A P T W L Sbjct: 3007 LAENEMGVAKKVVILVLQSAPVFQVEPQDMT-VRSGDDVALRCQATGEPTPT-IEW--LQ 3062 Query: 287 GSLPKGVEAQNRTL----FFKGPINYSLAGTYICEATNPIGTRSGQ 328 P + RTL + + AGTY C A N +G+ + + Sbjct: 3063 AGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATAR 3108 >gi|67188443 CD276 antigen isoform a [Homo sapiens] Length = 534 Score = 53.1 bits (126), Expect = 4e-07 Identities = 60/247 (24%), Positives = 98/247 (39%), Gaps = 22/247 (8%) Query: 15 GLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGS 74 G ALG F L G +V D + +GTD L CSF +P P + Q+ + Sbjct: 15 GAALGALWFCLTGA-LEVQVPEDPVVALVGTDATLCCSF-SPEPGFSLAQLNLIWQLTDT 72 Query: 75 KQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDG--TIRLSRLELEDEGVYICEFATFPTG 132 KQ +++ + G + Y R G ++RL R+ + DEG + C + G Sbjct: 73 KQ--LVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFG 130 Query: 133 NRESQLNLTV-MAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWE----T 187 + L + +KP+ +E K + + TC+S G P + V W+ Sbjct: 131 SAAVSLQVAAPYSKPSMTLEPN------KDLRPGDTVTITCSSYQGYPEAEVFWQDGQGV 184 Query: 188 RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKESLTLNVQY 245 L G ++ N G V S R+V + +C+V + S+T+ Q Sbjct: 185 PLTGNVTTSQMANEQGLFDVHSILRVVLGANG---TYSCLVRNPVLQQDAHSSVTITPQR 241 Query: 246 EPEVTIE 252 P +E Sbjct: 242 SPTGAVE 248 Score = 48.9 bits (115), Expect = 7e-06 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 17/190 (8%) Query: 33 VQV-NDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLA 91 VQV D + +GTD L CSF +P P + Q+ +KQ +++ + G + Sbjct: 249 VQVPEDPVVALVGTDATLRCSF-SPEPGFSLAQLNLIWQLTDTKQ--LVHSFTEGRDQGS 305 Query: 92 PYRERVEFLRPSFTDG--TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTV-MAKPTN 148 Y R G ++RL R+ + DEG + C + G+ L + +KP+ Sbjct: 306 AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSM 365 Query: 149 WIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWE----TRLKGEAEYQEIRNPNGT 204 +E K + + TC+S G P + V W+ L G ++ N G Sbjct: 366 TLEPN------KDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGL 419 Query: 205 VTVISRYRLV 214 V S R+V Sbjct: 420 FDVHSVLRVV 429 >gi|166295173 kin of IRRE like [Homo sapiens] Length = 757 Score = 53.1 bits (126), Expect = 4e-07 Identities = 53/234 (22%), Positives = 96/234 (41%), Gaps = 23/234 (9%) Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168 + ++ EL D+ Y C+ +R ++L + + + T G +L+A + Sbjct: 85 LEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHN---- 140 Query: 169 VATCTSANGKPPSVVSW---ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225 TC + N KP + + W T+ +G E+ T +S+ + P+ + Sbjct: 141 -LTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFT 199 Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283 C +N + KE S+ L+V + P VT+ + + V TC+A ANP Y W Sbjct: 200 CRSMNEAIPSGKETSIELDVHHPPTVTLS-IEPQTVQEGERVVFTCQATANPEILGYRWA 258 Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333 + E++ T FF P++ CE N +G+ + VN+ Sbjct: 259 KGGFLIEDAHESRYETNVDYSFFTEPVS--------CEVHNKVGSTNVSTLVNV 304 Score = 36.2 bits (82), Expect = 0.045 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%) Query: 209 SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLT 268 SRY + ++C V+ + S +NV + P + ++ + DV LT Sbjct: 270 SRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGS-DVTLT 328 Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNP-IGTRSG 327 C NPP T WT + ++ V + + L K + + AGTY C A P IG Sbjct: 329 CVWVGNPPLT-LTWTKKDSNM---VLSNSNQLLLKS-VTQADAGTYTCRAIVPRIGVAER 383 Query: 328 QVEVNI 333 +V + + Sbjct: 384 EVPLYV 389 >gi|13376852 CD276 antigen isoform b [Homo sapiens] Length = 316 Score = 52.8 bits (125), Expect = 5e-07 Identities = 53/207 (25%), Positives = 84/207 (40%), Gaps = 17/207 (8%) Query: 15 GLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGS 74 G ALG F L G +V D + +GTD L CSF +P P + Q+ + Sbjct: 15 GAALGALWFCLTGA-LEVQVPEDPVVALVGTDATLCCSF-SPEPGFSLAQLNLIWQLTDT 72 Query: 75 KQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDG--TIRLSRLELEDEGVYICEFATFPTG 132 KQ +++ + G + Y R G ++RL R+ + DEG + C + G Sbjct: 73 KQ--LVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFG 130 Query: 133 NRESQLNLTV-MAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWE----T 187 + L + +KP+ +E K + + TC+S G P + V W+ Sbjct: 131 SAAVSLQVAAPYSKPSMTLEPN------KDLRPGDTVTITCSSYRGYPEAEVFWQDGQGV 184 Query: 188 RLKGEAEYQEIRNPNGTVTVISRYRLV 214 L G ++ N G V S R+V Sbjct: 185 PLTGNVTTSQMANEQGLFDVHSVLRVV 211 >gi|4505243 myelin protein zero [Homo sapiens] Length = 258 Score = 52.8 bits (125), Expect = 5e-07 Identities = 33/124 (26%), Positives = 63/124 (50%), Gaps = 6/124 (4%) Query: 32 VVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMG---VS 88 VV + ++G +G+ V LHCSF + TW+ G + ++I++ + G + Sbjct: 41 VVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYID 100 Query: 89 VLAPYRERVEFL-RPSFTDGTIRLSRLELEDEGVYICEFATFP-TGNRESQLNLTVMAK- 145 + ++ER++++ P + DG+I + L+ D G + C+ P + SQ+ L V K Sbjct: 101 EVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKV 160 Query: 146 PTNW 149 PT + Sbjct: 161 PTRY 164 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,665,316 Number of Sequences: 37866 Number of extensions: 603903 Number of successful extensions: 2419 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 43 Number of HSP's successfully gapped in prelim test: 231 Number of HSP's that attempted gapping in prelim test: 1700 Number of HSP's gapped (non-prelim): 777 length of query: 352 length of database: 18,247,518 effective HSP length: 103 effective length of query: 249 effective length of database: 14,347,320 effective search space: 3572482680 effective search space used: 3572482680 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.