Guide to the Human Genome
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Search of human proteins with 12669911

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12669911 E2F transcription factor 1 [Homo sapiens]
         (437 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12669911 E2F transcription factor 1 [Homo sapiens]                 868   0.0  
gi|4503433 E2F transcription factor 3 [Homo sapiens]                  278   7e-75
gi|4758226 E2F transcription factor 2 [Homo sapiens]                  266   2e-71
gi|109637795 E2F transcription factor 6 [Homo sapiens]                160   3e-39
gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]      146   3e-35
gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]      144   2e-34
gi|12669915 E2F transcription factor 4 [Homo sapiens]                 137   2e-32
gi|134142813 E2F transcription factor 5 isoform 3 [Homo sapiens]       56   6e-08
gi|38505226 E2F family member 8 [Homo sapiens]                         55   1e-07
gi|145580626 E2F transcription factor 7 [Homo sapiens]                 50   3e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             41   0.002
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap...    40   0.004
gi|24308458 Lix1 homolog (mouse) like [Homo sapiens]                   40   0.004
gi|148806884 AKT1 substrate 1 (proline-rich) [Homo sapiens]            40   0.004
gi|148806906 AKT1 substrate 1 (proline-rich) [Homo sapiens]            40   0.004
gi|148806896 AKT1 substrate 1 (proline-rich) [Homo sapiens]            40   0.004
gi|6005900 transcription factor Dp-1 [Homo sapiens]                    40   0.005
gi|153791839 sodium channel associated protein 1 [Homo sapiens]        40   0.005
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...    39   0.007
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    39   0.007
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    39   0.012
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              39   0.012
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    38   0.021
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    38   0.021
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    38   0.021
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]          38   0.021
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         37   0.035
gi|122937271 WAS protein homolog associated with actin, golgi me...    37   0.035
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             37   0.046
gi|157785645 SPEG complex locus [Homo sapiens]                         37   0.046

>gi|12669911 E2F transcription factor 1 [Homo sapiens]
          Length = 437

 Score =  868 bits (2242), Expect = 0.0
 Identities = 437/437 (100%), Positives = 437/437 (100%)

Query: 1   MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD 60
           MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD
Sbjct: 1   MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCD 60

Query: 61  PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK 120
           PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK
Sbjct: 61  PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK 120

Query: 121 SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI 180
           SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI
Sbjct: 121 SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI 180

Query: 181 AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS 240
           AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS
Sbjct: 181 AKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDS 240

Query: 241 QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE 300
           QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE
Sbjct: 241 QRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPE 300

Query: 301 ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS 360
           ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS
Sbjct: 301 ETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLS 360

Query: 361 RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG 420
           RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG
Sbjct: 361 RMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEG 420

Query: 421 IRDLFDCDFGDLTPLDF 437
           IRDLFDCDFGDLTPLDF
Sbjct: 421 IRDLFDCDFGDLTPLDF 437


>gi|4503433 E2F transcription factor 3 [Homo sapiens]
          Length = 465

 Score =  278 bits (711), Expect = 7e-75
 Identities = 183/444 (41%), Positives = 245/444 (55%), Gaps = 50/444 (11%)

Query: 2   ALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDP 61
           AL  +P     A A  A      +   ++S     S+ Q  +    P  P+AP A     
Sbjct: 37  ALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAG 96

Query: 62  DLLLFATPQAPRPTPSAPR--PALGR--------PPVKRRLDL-ETDHQYLAESSGPARG 110
            LL + TP  P       +  PALGR        PP KRRL+L E+ HQYL++     +G
Sbjct: 97  SLL-YTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKG 155

Query: 111 RGR------HPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQK 164
           +GR         K  KSP EK+RY+TSL L TK+F++LLS S DGV+DLN AAEVLKVQK
Sbjct: 156 KGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQK 215

Query: 165 RRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTV--GVGGRLEGLTQDLRQLQESEQQLDH 222
           RRIYDITNVLEGI LI KKSKN++QW+G   +   G+  + +GL++++ +L + E++LD 
Sbjct: 216 RRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDE 275

Query: 223 LMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENF 282
           L+  CT  L+LL+ED+++QRLAYVT QD+R I+   +Q V+V+KAPPET+L+  DS E+ 
Sbjct: 276 LIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESL 335

Query: 283 QISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSL 342
           QI L S QGPI+V+LCPEET    SP KT +Q+                 P P+S   + 
Sbjct: 336 QIHLASTQGPIEVYLCPEETETH-SPMKTNNQDHNGN------------IPKPASKDLAS 382

Query: 343 TTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISL 402
           T                   G     V    LSPL +  +LL+   +     L   F++L
Sbjct: 383 TNS-----------------GHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNL 425

Query: 403 SPPHEALDYHFGLEEGEGIRDLFD 426
            PP    DY   L E EGI DLFD
Sbjct: 426 LPPLLQEDYLLSLGEEEGISDLFD 449


>gi|4758226 E2F transcription factor 2 [Homo sapiens]
          Length = 437

 Score =  266 bits (681), Expect = 2e-71
 Identities = 180/403 (44%), Positives = 227/403 (56%), Gaps = 39/403 (9%)

Query: 49  TGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPA 108
           T P A A G C     L ATP  P        PA GR P KR+LDLE   + +       
Sbjct: 52  TAPPAAAPGTC-----LDATPHGPEGQVVRCLPA-GRLPAKRKLDLEGIGRPVVPEFPTP 105

Query: 109 RGR-----GRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQ 163
           +G+     G    K  KSPGEK+RY+TSL L TK+F+ LLS S DGV+DLNWAAEVL VQ
Sbjct: 106 KGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQ 165

Query: 164 KRRIYDITNVLEGIQLIAKKSKNHIQWL--GSHTTVGVGGRLEGLTQDLRQLQESEQQLD 221
           KRRIYDITNVLEGIQLI KK+KN+IQW+  G        G+ + L Q+L++L  +EQ LD
Sbjct: 166 KRRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALD 225

Query: 222 HLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSE- 280
            L+  C+   + L+ED  ++RLAYVT QD+R++ +  EQ V+ +KAPP+T+L+  D +E 
Sbjct: 226 QLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTED 285

Query: 281 NFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPS 340
           N QI LKS QGPI+V+LCPEE            QE  S  E     ++T+   P S+ PS
Sbjct: 286 NLQIYLKSTQGPIEVYLCPEEV-----------QEPDSPSEEPLPSTSTLCPSPDSAQPS 334

Query: 341 SLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLE-------HVREDFSG 393
           S +TDPS    +    P  +       P     L PL A DSLLE          + F  
Sbjct: 335 S-STDPSIMEPTASSVPAPAPTPQQAPP--PPSLVPLEATDSLLELPHPLLQQTEDQFLS 391

Query: 394 ---LLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDC-DFGDL 432
                    IS SP  +  DY +GLE GEGI DLFD  D GDL
Sbjct: 392 PTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDL 434


>gi|109637795 E2F transcription factor 6 [Homo sapiens]
          Length = 281

 Score =  160 bits (404), Expect = 3e-39
 Identities = 104/295 (35%), Positives = 155/295 (52%), Gaps = 28/295 (9%)

Query: 61  PDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVK 120
           P LLL  T +  R     P    G  P K R++LE + QY++                VK
Sbjct: 11  PSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQYVS----------MRKALKVK 60

Query: 121 SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLI 180
            P    R++ SL   T++F++L+  +  G++DLN  A  L V+KRR+YDITNVL+GI L+
Sbjct: 61  RP----RFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLV 116

Query: 181 AKKSKNHIQWLGSH-TTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTD 239
            KKSKNHI+W+GS  +  G   + + L ++L  L   E  LD L+  C  QL  L++D +
Sbjct: 117 EKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKE 176

Query: 240 SQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQA-VDSSENFQISLKSKQGPIDVFLC 298
           ++RLAYVT QD+ SI    EQ+V+ +KAP ET+L       ++  + ++S  GPIDV+LC
Sbjct: 177 NERLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLC 236

Query: 299 PEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSL 353
             E            Q  TS + +    +++  S  P  P        S+ LL +
Sbjct: 237 EVE------------QGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEV 279


>gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]
          Length = 345

 Score =  146 bits (369), Expect = 3e-35
 Identities = 132/407 (32%), Positives = 185/407 (45%), Gaps = 91/407 (22%)

Query: 42  ASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYL 101
           A+A PA +G  APA              Q  RP P  P+    +PP   +L         
Sbjct: 2   AAAEPASSGQQAPAG-----------QGQGQRPPPQPPQAQAPQPPPPPQLG-------- 42

Query: 102 AESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLK 161
                         G G    G  SR+E SL L T +F+ LL  + DGV+DL  AA+ L 
Sbjct: 43  --------------GAG----GGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLA 84

Query: 162 V-QKRRIYDITNVLEGIQLIAKKSKNHIQWLG---SHTTVGVGGRLEGLTQDLRQLQESE 217
           V QKRRIYDITNVLEGI LI KKSKN IQW G      T  V  RL  L  ++  L+  E
Sbjct: 85  VRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKE 144

Query: 218 QQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQ--- 274
           ++LD         ++ + +D+ + R +YVT +D+ +  +     ++ I+AP  TQL+   
Sbjct: 145 RELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCFN--GDTLLAIQAPSGTQLEVPI 202

Query: 275 ---AVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIV 331
                +  + +QI+LKS  GPI V L  +E                      ++ S  +V
Sbjct: 203 PEMGQNGQKKYQINLKSHSGPIHVLLINKE----------------------SSSSKPVV 240

Query: 332 SPPPSSPPSSLTTDPSQSLL------------SLEQEPLLSRMGSLRAPVDEDRLSPLVA 379
            P P  PP  LT   SQSL             +L ++ +  R  +L+     D  S  ++
Sbjct: 241 FPVP--PPDDLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSIS 298

Query: 380 ADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFD 426
            D + E +  D   LL      LSP   A DY+F L++ EG+ DLFD
Sbjct: 299 GDIIDELMSSDVFPLL-----RLSPT-PADDYNFNLDDNEGVCDLFD 339


>gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]
          Length = 346

 Score =  144 bits (363), Expect = 2e-34
 Identities = 130/404 (32%), Positives = 180/404 (44%), Gaps = 84/404 (20%)

Query: 42  ASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYL 101
           A+A PA +G  APA              Q  RP P  P+    +PP   +L         
Sbjct: 2   AAAEPASSGQQAPAG-----------QGQGQRPPPQPPQAQAPQPPPPPQLG-------- 42

Query: 102 AESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLK 161
                         G G    G  SR+E SL L T +F+ LL  + DGV+DL  AA+ L 
Sbjct: 43  --------------GAG----GGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLA 84

Query: 162 V-QKRRIYDITNVLEGIQLIAKKSKNHIQWLG---SHTTVGVGGRLEGLTQDLRQLQESE 217
           V QKRRIYDITNVLEGI LI KKSKN IQW G      T  V  RL  L  ++  L+  E
Sbjct: 85  VRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKE 144

Query: 218 QQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQ--- 274
           ++LD         ++ + +D+ + R +YVT +D+ +  +     ++ I+AP  TQL+   
Sbjct: 145 RELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDICNCFN--GDTLLAIQAPSGTQLEVPI 202

Query: 275 ---AVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIV 331
                +  + +QI+LKS  GPI V L  +E                      ++ S  +V
Sbjct: 203 PEMGQNGQKKYQINLKSHSGPIHVLLINKE----------------------SSSSKPVV 240

Query: 332 SPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVD--EDRLSPLVAADSLLEHVRE 389
            P P  PP  LT   SQSL  +   P  S M +   P     +R   L    +       
Sbjct: 241 FPVP--PPDDLTQPSSQSLTPV--TPQKSSMATQNLPEQHVSERSQALQQTSATDISSAG 296

Query: 390 DFSGLLPEEFISLS-------PPHEALDYHFGLEEGEGIRDLFD 426
             SG + +E +S          P  A DY+F L++ EG+ DLFD
Sbjct: 297 SISGDIIDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFD 340


>gi|12669915 E2F transcription factor 4 [Homo sapiens]
          Length = 413

 Score =  137 bits (345), Expect = 2e-32
 Identities = 129/398 (32%), Positives = 172/398 (43%), Gaps = 95/398 (23%)

Query: 122 PGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKV-QKRRIYDITNVLEGIQLI 180
           PG  SR+E SL L T +F+ LL  + DGV+DL  AA+ L V QKRRIYDITNVLEGI LI
Sbjct: 12  PGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVLEGIGLI 71

Query: 181 AKKSKNHIQWLG---SHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSED 237
            KKSKN IQW G      T  +  +L  L  ++ +LQ+ EQ+LD         +R ++ED
Sbjct: 72  EKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELDQHKVWVQQSIRNVTED 131

Query: 238 TDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQL-----QAVDSSENFQISLKSKQGP 292
             +  LAYVT +D+      A   ++ I+AP  T L     + ++  + +QI LKS  GP
Sbjct: 132 VQNSCLAYVTHEDICRCF--AGDTLLAIRAPSGTSLEVPIPEGLNGQKKYQIHLKSVSGP 189

Query: 293 IDVFLC----------------PEETVGGISPGKTP----------SQEVTSEEENRATD 326
           I+V L                 PE+ +   S   TP          SQE +     + T 
Sbjct: 190 IEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQEASRPNSPQLTP 249

Query: 327 SAT----------------IVSPPPSSP-------------PSSLTTDPSQSLLSLEQEP 357
           +A                  VS  P +              P++L T P QS   L+   
Sbjct: 250 TAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQSSALLDSSS 309

Query: 358 LLSRMGSLRA-----------------PVDEDRLSPLVAADSLLE---HVREDFSGLLPE 397
             S   S  +                 P+  D    L     L E     RE  S  L E
Sbjct: 310 SSSSSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDPTRECMSSELLE 369

Query: 398 EFIS---------LSPPHEALDYHFGLEEGEGIRDLFD 426
           E +S         LSPP    DY + L+E EG+ DLFD
Sbjct: 370 ELMSSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFD 407


>gi|134142813 E2F transcription factor 5 isoform 3 [Homo sapiens]
          Length = 185

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 57/206 (27%), Positives = 88/206 (42%), Gaps = 43/206 (20%)

Query: 236 EDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAV------DSSENFQISLKSK 289
           +D+ + R +YVT +D+ +  +     ++ I+AP  TQL+        +  + +QI+LKS 
Sbjct: 2   DDSINNRFSYVTHEDICNCFNG--DTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSH 59

Query: 290 QGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQS 349
            GPI V L  +E+                      + S  +V P P  PP  LT   SQS
Sbjct: 60  SGPIHVLLINKES----------------------SSSKPVVFPVP--PPDDLTQPSSQS 95

Query: 350 LLSLEQEPLLSRMGSLRAPVDE--DRLSPLVAADSLLEHVREDFSGLLPEEFISLS---- 403
           L  +   P  S M +   P     +R   L    +         SG + +E +S      
Sbjct: 96  LTPVT--PQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISGDIIDELMSSDVFPL 153

Query: 404 ---PPHEALDYHFGLEEGEGIRDLFD 426
               P  A DY+F L++ EG+ DLFD
Sbjct: 154 LRLSPTPADDYNFNLDDNEGVCDLFD 179


>gi|38505226 E2F family member 8 [Homo sapiens]
          Length = 867

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 12/112 (10%)

Query: 124 EKSRYETSLNLTTKRFLELLSHSADGVVD----LNWAAEVLKVQKRRIYDITNVLEGIQL 179
           + SR E SL L   +FL    +  +  V+    L+  AE L V++RRIYDI NVLE + +
Sbjct: 110 QPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHM 169

Query: 180 IAKKSKNHIQWLGSHTTVGVGGRLEGLTQD--------LRQLQESEQQLDHL 223
           +++ +KN   W G H      G L+ + ++        + + +E EQ+ D +
Sbjct: 170 VSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFI 221



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 14/82 (17%)

Query: 115 PGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVL-------------- 160
           PG   ++    SR + SL + +++F+ L   S   +V L  AA++L              
Sbjct: 249 PGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKF 308

Query: 161 KVQKRRIYDITNVLEGIQLIAK 182
           K + RR+YDI NVL  + LI K
Sbjct: 309 KTKIRRLYDIANVLSSLDLIKK 330


>gi|145580626 E2F transcription factor 7 [Homo sapiens]
          Length = 911

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 8/102 (7%)

Query: 126 SRYETSLNLTTKRFLELLSH----SADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIA 181
           SR + SL L  ++FL         +    + L+  A  L V++RRIYDI NVLE + L++
Sbjct: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVS 200

Query: 182 KKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHL 223
           + +KN   W G H+       L+ L ++    Q+ E+Q+ +L
Sbjct: 201 RVAKNQYGWHGRHSLPKTLRNLQRLGEE----QKYEEQMAYL 238



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 121 SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVL-------------KVQKRRI 167
           S    SR + SL + +++F+ L   S   +V L+ AA++L             K + RR+
Sbjct: 276 SSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRL 335

Query: 168 YDITNVLEGIQLIAK 182
           YDI NVL  + LI K
Sbjct: 336 YDIANVLTSLALIKK 350


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 20/158 (12%)

Query: 4    AGAPAGGPC-APALEALLGAGALRLLDSSQIVIISAAQDASAPPAP------------TG 50
            + APA  P   P L ++    ++ +L S+ I I+++A  +++ P P            T 
Sbjct: 1831 SSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITA 1890

Query: 51   PAAPAAGPCDPDLLLFATPQAPRPTP---SAPRPALGRPPVKRRLDLETDHQYLAESSGP 107
            P  PA+ P     L  A+  AP P P   SAP PA   PP   +   +T H+ +      
Sbjct: 1891 PTIPASAPTASVPLAPASASAPAPAPTPVSAPNPA---PPAPAQTQAQT-HKPVQNPLQT 1946

Query: 108  ARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSH 145
                 + P   ++ P  ++   T    + K      SH
Sbjct: 1947 TSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSH 1984


>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo
           sapiens]
          Length = 288

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 28/80 (35%), Positives = 31/80 (38%)

Query: 7   PAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLLLF 66
           PA GP A AL A+  A A     S       AA  A+A PA   PAA   G   P     
Sbjct: 152 PAAGPPAAALAAVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGAAGPSAASL 211

Query: 67  ATPQAPRPTPSAPRPALGRP 86
                P   P+A  PA   P
Sbjct: 212 CAASQPAAVPAAASPAAAAP 231



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 8/59 (13%)

Query: 37  SAAQDASAPPAPTGPAAPAAGPC----DPDL--LLFATPQA--PRPTPSAPRPALGRPP 87
           +AA  A  PPA   PAA  A  C    DP    L  A+P A  P   P+A RP    PP
Sbjct: 99  AAAPAAVRPPAAGPPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPP 157



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 26/82 (31%), Positives = 32/82 (39%), Gaps = 6/82 (7%)

Query: 4   AGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAA------PAAG 57
           AG PA  P A    A   + A     S    + +A   A  PPA   PAA      PAA 
Sbjct: 110 AGPPAAAPAAVCPAAADPSAASLCAASPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAA 169

Query: 58  PCDPDLLLFATPQAPRPTPSAP 79
                 L  A+P A  P  ++P
Sbjct: 170 DPSAASLCAASPLAAVPAAASP 191


>gi|24308458 Lix1 homolog (mouse) like [Homo sapiens]
          Length = 337

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 21 GAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPR 80
          G G LR L      +  AA   + PPA   PA P   P  P LLL   P  P P  +A  
Sbjct: 17 GRGTLRALRPG---VTGAAAATATPPAGPPPAPPPPAPPPPPLLLSGAPGLPLPPGAAGS 73

Query: 81 PALGRPPVK 89
          PA+ R  V+
Sbjct: 74 PAVLREAVE 82


>gi|148806884 AKT1 substrate 1 (proline-rich) [Homo sapiens]
          Length = 256

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 21/102 (20%)

Query: 7   PAGGPCAPALEA--LLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLL 64
           P  GPCA A      L   A R L    I +   A  A+ PPAP     PA         
Sbjct: 39  PRPGPCAYAAHGRGALAEAARRCLHD--IALAHRAATAARPPAPP----PA--------- 83

Query: 65  LFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSG 106
               PQ P PTPS PRP L R   +   D  T+ +   E  G
Sbjct: 84  ----PQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQLG 121


>gi|148806906 AKT1 substrate 1 (proline-rich) [Homo sapiens]
          Length = 256

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 21/102 (20%)

Query: 7   PAGGPCAPALEA--LLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLL 64
           P  GPCA A      L   A R L    I +   A  A+ PPAP     PA         
Sbjct: 39  PRPGPCAYAAHGRGALAEAARRCLHD--IALAHRAATAARPPAPP----PA--------- 83

Query: 65  LFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSG 106
               PQ P PTPS PRP L R   +   D  T+ +   E  G
Sbjct: 84  ----PQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQLG 121


>gi|148806896 AKT1 substrate 1 (proline-rich) [Homo sapiens]
          Length = 256

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 21/102 (20%)

Query: 7   PAGGPCAPALEA--LLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLL 64
           P  GPCA A      L   A R L    I +   A  A+ PPAP     PA         
Sbjct: 39  PRPGPCAYAAHGRGALAEAARRCLHD--IALAHRAATAARPPAPP----PA--------- 83

Query: 65  LFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSG 106
               PQ P PTPS PRP L R   +   D  T+ +   E  G
Sbjct: 84  ----PQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQLG 121


>gi|6005900 transcription factor Dp-1 [Homo sapiens]
          Length = 410

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 17/127 (13%)

Query: 104 SSGPARGRGRHPGKGVKSPGEK------SRYETSLNLTTKRFLELLSHSADGVVDLNWAA 157
           S+G    +G   GKG++    K       +  TS N      +   S +AD  +  N +A
Sbjct: 101 SAGKRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAEFS-AADNHILPNESA 159

Query: 158 EVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTT---------VGVGGRLEGLTQ 208
              K  +RR+YD  NVL  + +I+K+ K  I+W+G  T          V    RLE + Q
Sbjct: 160 YDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNSAQECQNLEVERQRRLERIKQ 218

Query: 209 DLRQLQE 215
              QLQE
Sbjct: 219 KQSQLQE 225


>gi|153791839 sodium channel associated protein 1 [Homo sapiens]
          Length = 688

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 25/175 (14%)

Query: 131 SLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKR----RIYDITNVLEGIQLIAKKSKN 186
           ++ +T ++FL+ ++  +  +  L       K++ R    ++ ++TNV E +Q   KK + 
Sbjct: 202 NMEVTNQQFLKTVTEQSVIIEQLRKKLRQAKLELRVAVAKVEELTNVTEDLQGQMKKKEK 261

Query: 187 HIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTT-----QLRLLSEDTDSQ 241
            +        V   GR E   + L+QLQ S +QL+  + +C T     QLR  +   + Q
Sbjct: 262 DV--------VSAHGREEASDRRLQQLQSSIKQLE--IRLCVTIQEANQLRTENTHLEKQ 311

Query: 242 -RLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDV 295
            R     C +L +     E+   +++A    QL    + +  Q  L+ KQ   D+
Sbjct: 312 TRELQAKCNELEN-----ERYEAIVRARNSMQLLEEANLQKSQALLEEKQKEEDI 361


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
            sapiens]
          Length = 2113

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 8/78 (10%)

Query: 44   APPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAE 103
            APPA T P AP   P +P       P A  P PS   P  G P  K    +      L E
Sbjct: 2038 APPAGTAPPAPGPTPAEPP----TAPSAAPPAPSTEPPRAGGPHTK----MGGSRDSLLE 2089

Query: 104  SSGPARGRGRHPGKGVKS 121
             S    GR +  G G  S
Sbjct: 2090 MSTSGVGRSQKQGAGAYS 2107


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 20/94 (21%)

Query: 42  ASAPPA--PTGPAAPAAGP----CDPDLLLFATPQAPRPT------PSAPRPALGRPPVK 89
           +SAPPA  PT  A P +GP      P  +  A P AP PT      P+ P  A G PP  
Sbjct: 129 SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188

Query: 90  RRLDLETDHQYLAESSGPARGRGRHPGKGVKSPG 123
             +             GP +G G    KG K PG
Sbjct: 189 AAVP--------GPGPGPKQGPGPGGPKGGKMPG 214


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 51/178 (28%), Positives = 59/178 (33%), Gaps = 32/178 (17%)

Query: 4   AGAPAGGPCAPALEALLGAG-----ALRLLDSSQIVIISAAQDASAPPAPTGPAAPAA-- 56
           AGA   GP APA E   GA      A R                  P  P GPA PAA  
Sbjct: 68  AGAAGAGPAAPA-EGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126

Query: 57  --------GPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPA 108
                   G C P     A    P P P+ P    G                LA  +GP 
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAA-------------LAARAGPG 173

Query: 109 RGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDL--NWAAEVLKVQK 164
            G G  PG G   PG+ +    +  L     L    H+A   V L  N  A +L + K
Sbjct: 174 PGPGPGPGPG-PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 4   AGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDL 63
           AG PAG    P   A   A A  +   S   ++ AA  A+   A +GPA+ AA      +
Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAA-----SM 373

Query: 64  LLFATPQAPRPTPSA-PRPALGRP 86
           ++  T Q   P+P+A P PA G P
Sbjct: 374 VIGPTMQGALPSPAAVPPPAPGTP 397



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 13/49 (26%)

Query: 42  ASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPA---LGRPP 87
           A+APPAP  P+ PAA            P AP   P  P PA   L RPP
Sbjct: 246 AAAPPAPAAPSPPAA----------PAPAAPAAAPPPPPPAPATLARPP 284



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 8/95 (8%)

Query: 39  AQDASAPPAPTGPAAPAAGPCDP---DLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLE 95
           A  A +PPA   PAAPAA P  P      L   P  P   P+A  PA+  P   +     
Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA-APAVPPPAAAQNGGSA 309

Query: 96  TDHQYLAESSGPARGRGRHPGKG----VKSPGEKS 126
                 A ++G   G    PG G      +PG K+
Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 10/59 (16%)

Query: 38  AAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPS----------APRPALGRP 86
           AA  A+ PP P  PA  A  P  P     A P  P P  +          AP PA G P
Sbjct: 264 AAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 40  QDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRP-ALGRPPVKRRLDLETDH 98
           Q  SAPP P  P+ P        L     PQAP P P A  P ALGRPP    ++ +   
Sbjct: 668 QQGSAPPTPVPPSPPQ----PVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRW 723

Query: 99  QYLAESSGPARGRGRHP 115
             +     P   +GR P
Sbjct: 724 MMIPPYVDPRLLQGRPP 740



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 16/132 (12%)

Query: 7    PAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPC-DPDLLL 65
            P+G P    L        L ++DS   V+   +   + PPAP   +    GP   P  L 
Sbjct: 1971 PSGAPAQQML--------LPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLA 2022

Query: 66   FATPQAPR----PTPSAPRPA-LGRPPVKR-RLDLETDHQYLAESSGPARGRGRHPGKGV 119
               P AP     P+P+ P PA LGR  +    L    D+Q L+ + G   G  R P  G 
Sbjct: 2023 VRPPPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLG-GPGSSRTPPTGR 2081

Query: 120  KSPGEKSRYETS 131
               G  SR + +
Sbjct: 2082 SFSGLNSRLKAT 2093


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 19/39 (48%), Positives = 19/39 (48%), Gaps = 1/39 (2%)

Query: 45  PPAPTGPAAPAA-GPCDPDLLLFATPQAPRPTPSAPRPA 82
           PP P GP  P   GP  P L L   P  P P P AP PA
Sbjct: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 14/98 (14%)

Query: 3   LAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPD 62
           L  AP   P +P ++A     A   +  S      A    +APP    P+ PA+ P  P 
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494

Query: 63  LLLFATPQAP-----------RPTPSAPRPALGRPPVK 89
                 PQAP           +P P AP PAL  PP++
Sbjct: 495 AT--PPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQ 529



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 1/86 (1%)

Query: 2   ALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDP 61
           ALA  P   P +P     L   A     +   + +   Q   +PP      AP + P  P
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458

Query: 62  DLLLFATPQAPRPTPSAPRPALGRPP 87
            +   ATP +  P PS   P L  PP
Sbjct: 459 PVSPSATPPSQAP-PSLAAPPLQVPP 483


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 14/98 (14%)

Query: 3   LAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPD 62
           L  AP   P +P ++A     A   +  S      A    +APP    P+ PA+ P  P 
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 63  LLLFATPQAP-----------RPTPSAPRPALGRPPVK 89
                 PQAP           +P P AP PAL  PP++
Sbjct: 456 AT--PPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQ 490



 Score = 32.3 bits (72), Expect = 0.87
 Identities = 23/49 (46%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 42  ASAPPAPTGP---AAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPP 87
           A  PP  T P   AAPA GP     L   +P AP P+PSAP P+L   P
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP-PSPSAP-PSLQTLP 316



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 1/86 (1%)

Query: 2   ALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDP 61
           ALA  P   P +P     L   A     +   + +   Q   +PP      AP + P  P
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419

Query: 62  DLLLFATPQAPRPTPSAPRPALGRPP 87
            +   ATP +  P PS   P L  PP
Sbjct: 420 PVSPSATPPSQAP-PSLAAPPLQVPP 444


>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
          Length = 951

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 45/179 (25%), Positives = 67/179 (37%), Gaps = 27/179 (15%)

Query: 209 DLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAP 268
           +L Q    + +LD L N   T+ +L  E+ + +R A           D A Q    +K P
Sbjct: 127 ELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKA----------TDAAYQARQAVKTP 176

Query: 269 PETQLQAVDSSENFQISLKSKQGPIDVFLCP---EETVGGISPGKTPSQEVTSEEENRAT 325
           P  +L  V        +      P+   L P   EE   G++PG  PS  VTS       
Sbjct: 177 PR-RLPTVMVRSPIDSASPGGDYPLGD-LTPTTMEEATSGVTPGTLPSTPVTS------- 227

Query: 326 DSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLL 384
                   P + PP S   +   + ++ +  P    +G    P     LS L+   SLL
Sbjct: 228 ----FPGIPDTLPPGSAPLEAPMTPVT-DDSPQKKMLGQKATPPPSPLLSELLKKGSLL 281


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 6/65 (9%)

Query: 35   IISAAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDL 94
            +I   +D S PPA   PA P++ P  P       P +P PTP   R       V  + DL
Sbjct: 1008 VIQKLEDVSKPPAYAYPATPSSHPTSP------PPASPPPTPGITRKEEAPENVVEKKDL 1061

Query: 95   ETDHQ 99
            E + +
Sbjct: 1062 ELEKE 1066



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 5/103 (4%)

Query: 42   ASAPPA--PTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQ 99
            A+A P   P  P   AAGP        + P +PR +P A   AL    +++  D+     
Sbjct: 964  ATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVA---ALKAKVIQKLEDVSKPPA 1020

Query: 100  YLAESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLEL 142
            Y   ++  +      P     +PG   + E   N+  K+ LEL
Sbjct: 1021 YAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLEL 1063



 Score = 29.3 bits (64), Expect = 7.4
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)

Query: 38   AAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSA-------PRPALGRPPVKR 90
            ++ D +AP    GP+A AA P        AT QA +  PSA       P P    PP + 
Sbjct: 2680 SSDDEAAPAPTAGPSAQAALPTK------ATKQAGKARPSAHSPGKKTPAPQPQAPPPQP 2733

Query: 91   RLDLETDHQYLAESSGPARGRGRH 114
               L+   Q  A+S  P +  G H
Sbjct: 2734 TQPLQPKAQAGAKSR-PKKREGVH 2756


>gi|122937271 WAS protein homolog associated with actin, golgi
           membranes and microtubules [Homo sapiens]
          Length = 809

 Score = 37.0 bits (84), Expect = 0.035
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 20/109 (18%)

Query: 333 PPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLV-------------- 378
           PPP  PP      P ++L S  Q      +G  RAPV +D+  PLV              
Sbjct: 645 PPPPPPPPPPPPPPLRALSSSSQAATHQNLG-FRAPVKDDQPRPLVCESPAERPRDSLES 703

Query: 379 -----AADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIR 422
                + D +L  +R   + L   E  ++ PPH +++ H      +G++
Sbjct: 704 FSCPGSMDEVLASLRHGRAPLRKVEVPAVRPPHASINEHILAAIRQGVK 752


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 36.6 bits (83), Expect = 0.046
 Identities = 44/143 (30%), Positives = 57/143 (39%), Gaps = 16/143 (11%)

Query: 2   ALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDP 61
           A A A A    A A  A  G+GA   LD ++      A+++        P+A + GP D 
Sbjct: 466 AKAVAAAVAAAAAAAAAAAGSGAPEPLDGAE-----PAKESGLGAEERCPSALSRGPLDE 520

Query: 62  DLL--LFATPQAPRPTPSAPRPALG------RPPVKRRLDLETDHQYLAES--SGPARGR 111
           D        P AP P P  P    G      RP VK    +   +    E+  +GPARG 
Sbjct: 521 DGTDEALPPPLAPLPPPPPPPARKGSYVSAFRPVVKDTESIAKLYGSAREAYGAGPARGP 580

Query: 112 GRHPGK-GVKSPGEKSRYETSLN 133
           G   G  G  SP   S   +S N
Sbjct: 581 GPGAGSGGYVSPDFLSEGSSSYN 603


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 36.6 bits (83), Expect = 0.046
 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 12/87 (13%)

Query: 4    AGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDL 63
            AGAP   P A         GA RL +S  +  +S AQ +S P  P+ P        +P  
Sbjct: 2145 AGAPLEIPVARL-------GARRLQESPSLSALSEAQPSS-PARPSAPKPSTPKSAEPS- 2195

Query: 64   LLFATPQAPRPTPSAPRPALGRPPVKR 90
               AT  +  P P AP+PA  + P  R
Sbjct: 2196 ---ATTPSDAPQPPAPQPAQDKAPEPR 2219



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 9/108 (8%)

Query: 247 TCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPEET--VG 304
           T Q   S  +P E  +    + P+T  +AV  +     S  S + P D    P      G
Sbjct: 520 TLQRAPSPREPGEPPLFSRPSTPKTS-RAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAG 578

Query: 305 GISPGKTPSQEVTSEEENRATDSATI------VSPPPSSPPSSLTTDP 346
              PG+ P QEV   ++   T S  I      V PP + PP + T  P
Sbjct: 579 RTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAP 626



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 32/86 (37%), Positives = 38/86 (44%), Gaps = 9/86 (10%)

Query: 4    AGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDL 63
            A  PA  P   AL+ L    AL L   +QI I S      A     GPAAP + P  P  
Sbjct: 2225 ASKPAPPP--QALQTL----ALPLTPYAQI-IQSLQLSGHAQGPSQGPAAPPSEP-KPHA 2276

Query: 64   LLFATPQAPRP-TPSAPRPALGRPPV 88
             +FA   +P P  P    P+ G PPV
Sbjct: 2277 AVFARVASPPPGAPEKRVPSAGGPPV 2302


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,844,358
Number of Sequences: 37866
Number of extensions: 1132269
Number of successful extensions: 8934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 416
Number of HSP's that attempted gapping in prelim test: 7356
Number of HSP's gapped (non-prelim): 1773
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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