Guide to the Human Genome
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Name: HACE1 Sequence: fasta or formatted (909aa) NCBI GI: 116875852
Description:

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

Referenced in:

Ankyrin Family
Ubiquitin and Related Protein Modifications

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         53           2
 C cysteine            2.5         23           2
 D aspartate           5.2         47           1
 E glutamate           6.4         58           2
 F phenylalanine       4.1         37           1
 G glycine             5.9         54           3
 H histidine           3.2         29           1
 I isoleucine          5.4         49           2
 K lysine              4.0         36           2
 L leucine            11.2        102           3
 M methionine          3.1         28           1
 N asparagine          5.5         50           2
 P proline             5.0         45           2
 Q glutamine           5.3         48           2
 R arginine            4.7         43           2
 S serine              7.2         65           2
 T threonine           5.0         45           2
 V valine              6.5         59           2
 W tryptophan          1.0          9           1
 Y tyrosine            3.2         29           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HECT domain and ankyrin repeat containing, E3 ubiqu... 
HUWE1                 0.154   HECT, UBA and WWE domain containing 1 
ITCH                  0.150   itchy homolog E3 ubiquitin protein ligase 
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally dow...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4L                0.144   neural precursor cell expressed, developmentally do...
NEDD4                 0.141   neural precursor cell expressed, developmentally do...
NEDD4                 0.141   neural precursor cell expressed, developmentally do...
WWP1                  0.140   WW domain containing E3 ubiquitin protein ligase 1 [...
WWP2                  0.139   WW domain containing E3 ubiquitin protein ligase 2 i...
WWP2                  0.139   WW domain containing E3 ubiquitin protein ligase 2 i...
SMURF1                0.135   Smad ubiquitination regulatory factor 1 isoform 1 [H...
SMURF1                0.135   Smad ubiquitination regulatory factor 1 isoform 2 [H...
HECW1                 0.134   NEDD4-like ubiquitin-protein ligase 1 
SMURF2                0.132   SMAD specific E3 ubiquitin protein ligase 2 
HECW2                 0.132   HECT, C2 and WW domain containing E3 ubiquitin prote...
KIAA0317              0.092   hypothetical protein LOC9870 
UBE3A                 0.092   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.092   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.092   ubiquitin protein ligase E3A isoform 2 
UBE3C                 0.087   ubiquitin protein ligase E3C 
HECTD2                0.086   HECT domain containing 2 isoform a 
UBE3B                 0.083   ubiquitin protein ligase E3B 
UBE3B                 0.083   ubiquitin protein ligase E3B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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