ITCH 24382

Name: ITCH	Sequence: fasta or formatted (862aa)		NCBI GI: 27477109
Description: itchy homolog E3 ubiquitin protein ligase		Referenced in: Gap Junctions and Tight Junctions Ubiquitin and Related Protein Modifications WW Domain
Composition: Amino acid Percentage Count Longest homopolymer A alanine 3.2 28 2 C cysteine 1.3 11 1 D aspartate 5.2 45 2 E glutamate 7.5 65 2 F phenylalanine 4.9 42 2 G glycine 7.3 63 2 H histidine 1.7 15 1 I isoleucine 4.5 39 2 K lysine 5.5 47 2 L leucine 8.4 72 2 M methionine 2.0 17 1 N asparagine 5.3 46 2 P proline 6.8 59 4 Q glutamine 5.6 48 2 R arginine 6.0 52 3 S serine 7.3 63 2 T threonine 6.4 55 3 V valine 5.3 46 3 W tryptophan 2.3 20 1 Y tyrosine 3.4 29 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 itchy homolog E3 ubiquitin protein ligase WWP1 0.596 WW domain containing E3 ubiquitin protein ligase 1 [... WWP2 0.540 WW domain containing E3 ubiquitin protein ligase 2 i... WWP2 0.373 WW domain containing E3 ubiquitin protein ligase 2 i... NEDD4 0.283 neural precursor cell expressed, developmentally do... NEDD4 0.283 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally dow... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... NEDD4L 0.282 neural precursor cell expressed, developmentally do... SMURF2 0.262 SMAD specific E3 ubiquitin protein ligase 2 SMURF1 0.253 Smad ubiquitination regulatory factor 1 isoform 2 [H... SMURF1 0.249 Smad ubiquitination regulatory factor 1 isoform 1 [H... HECW1 0.198 NEDD4-like ubiquitin-protein ligase 1 HECW2 0.197 HECT, C2 and WW domain containing E3 ubiquitin prote... HUWE1 0.176 HECT, UBA and WWE domain containing 1 HACE1 0.154 HECT domain and ankyrin repeat containing, E3 ubiqu... HECTD2 0.110 HECT domain containing 2 isoform a KIAA0317 0.100 hypothetical protein LOC9870 UBE3A 0.100 ubiquitin protein ligase E3A isoform 3 UBE3A 0.100 ubiquitin protein ligase E3A isoform 1 UBE3A 0.100 ubiquitin protein ligase E3A isoform 2 HERC3 0.090 hect domain and RLD 3 UBE3B 0.089 ubiquitin protein ligase E3B UBE3B 0.089 ubiquitin protein ligase E3B Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.