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Search of human proteins with 42475534
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42475534 calsyntenin 3 [Homo sapiens]
(956 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42475534 calsyntenin 3 [Homo sapiens] 1965 0.0
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens] 1024 0.0
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens] 1016 0.0
gi|209364544 calsyntenin 2 [Homo sapiens] 892 0.0
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 64 7e-10
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 60 1e-08
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 56 1e-07
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 55 2e-07
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 55 2e-07
gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs... 54 5e-07
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs... 54 5e-07
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 54 5e-07
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 54 5e-07
gi|190194360 protocadherin 20 [Homo sapiens] 53 2e-06
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 52 2e-06
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 52 2e-06
gi|16933565 protocadherin 21 precursor [Homo sapiens] 52 2e-06
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 52 2e-06
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 52 3e-06
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens] 52 3e-06
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 49 3e-05
gi|47059046 dachsous 2 isoform 1 [Homo sapiens] 48 4e-05
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 47 7e-05
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 47 7e-05
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 47 7e-05
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 47 7e-05
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 47 7e-05
gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo sapi... 47 7e-05
gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo sapi... 47 7e-05
gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo sapi... 47 7e-05
>gi|42475534 calsyntenin 3 [Homo sapiens]
Length = 956
Score = 1965 bits (5090), Expect = 0.0
Identities = 956/956 (100%), Positives = 956/956 (100%)
Query: 1 MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLR 60
MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLR
Sbjct: 1 MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLR 60
Query: 61 YAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDG 120
YAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDG
Sbjct: 61 YAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDG 120
Query: 121 ANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQI 180
ANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQI
Sbjct: 121 ANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQI 180
Query: 181 CYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKP 240
CYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKP
Sbjct: 181 CYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKP 240
Query: 241 TCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNY 300
TCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNY
Sbjct: 241 TCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNY 300
Query: 301 SERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPS 360
SERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPS
Sbjct: 301 SERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPS 360
Query: 361 GLGSGPQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIA 420
GLGSGPQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIA
Sbjct: 361 GLGSGPQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIA 420
Query: 421 FLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIH 480
FLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIH
Sbjct: 421 FLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIH 480
Query: 481 PPRREPALMIGACWTEEKNKEKEKGDNSTDTTQGDPLSIHHYFHGYLAGFSVRSGRLESR 540
PPRREPALMIGACWTEEKNKEKEKGDNSTDTTQGDPLSIHHYFHGYLAGFSVRSGRLESR
Sbjct: 481 PPRREPALMIGACWTEEKNKEKEKGDNSTDTTQGDPLSIHHYFHGYLAGFSVRSGRLESR 540
Query: 541 EVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLR 600
EVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLR
Sbjct: 541 EVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLR 600
Query: 601 FATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFEG 660
FATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFEG
Sbjct: 601 FATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFEG 660
Query: 661 TNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPE 720
TNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPE
Sbjct: 661 TNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPE 720
Query: 721 RESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRL 780
RESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRL
Sbjct: 721 RESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRL 780
Query: 781 SCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHR 840
SCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHR
Sbjct: 781 SCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHR 840
Query: 841 NSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDS 900
NSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDS
Sbjct: 841 NSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDS 900
Query: 901 ALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDERRIIETPPHRY 956
ALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDERRIIETPPHRY
Sbjct: 901 ALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDERRIIETPPHRY 956
>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
Length = 971
Score = 1024 bits (2647), Expect = 0.0
Identities = 495/947 (52%), Positives = 677/947 (71%), Gaps = 31/947 (3%)
Query: 8 LLLASLLASCS--CNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
LLLA LL + NKHKPW+E Y GIV ENDNTVLL+PPL ALDKDAPLR+AGEI
Sbjct: 15 LLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAGEI 74
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
CGF++HG VPF+AV++DK+TGEG+IR+KE +DCE QK+++FTIQAYDCG+GPDG N KK
Sbjct: 75 CGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKK 134
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEI 185
SHKATVH++VNDVNE+APVF E+ Y+A V EGK YD ILRVEA+D DCSPQ+SQIC YEI
Sbjct: 135 SHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEI 194
Query: 186 LTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPS 245
+TP+ PF +D DG I+NTEKL Y E YK TVTAYDCGKKRA +D V+I +KPTC P
Sbjct: 195 ITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPG 254
Query: 246 WQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNYSERAL 305
WQGWN RIEY PG G+LA+FP I LETCDEP+ ++QAT+EL+TSH+ KGCDRD YSE++L
Sbjct: 255 WQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSL 314
Query: 306 RKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPSGLGSG 365
+LCGAA G +LLP P + NWT GL DS ++ FNGTQAV++P G S
Sbjct: 315 HRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVS----- 369
Query: 366 PQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYW- 424
S + FT+S WM+HG K +ETI+C++ + + HYSL VHGCR+ FL+
Sbjct: 370 --VSPKEPFTISVWMRHGPFGRK----KETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQ 423
Query: 425 -PLLESA-RPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIHPP 482
P E RP +F WKL QVCD+EWHHY LN+EFP+VTLY DG S +P + ++ +HP
Sbjct: 424 DPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPS 483
Query: 483 RREPALMIGACWTEEKNKEKEKGDNSTD----TTQGDPLSIHHYFHGYLAGFSVRSGRLE 538
+ E L++GACW E E DN T+ + G L + +F G LAG ++RSG+L
Sbjct: 484 KIETQLVVGACWQEFSGVE---NDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLA 540
Query: 539 SREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNT 598
++VI+CLY C+EGLD + E G+G+++ +PSQ +LTLEG+D+ + A+QH++Y+N+
Sbjct: 541 DKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNS 600
Query: 599 LRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDF 658
+F TPG+R L++T+ +KCF+E +C+S+P V+GYV+VLQP+ P+I LSG HFAR A +F
Sbjct: 601 RQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEF 660
Query: 659 EGTNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLD 718
E + GV LFP+L+I +I+ +VE + D + TV ++ +S+EIVH+LD CE+++ G++L+
Sbjct: 661 ESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELN 720
Query: 719 PERESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKF 778
E+ESL +D LQQ+G+E++++ +T GV+++ YEE+L RYR H +L RKF
Sbjct: 721 HEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKF 780
Query: 779 RLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASS 838
+L CSE+NGRY SNEF VEVNV+H+ N + H +H+ + QF+H H+ +++GH+LA+
Sbjct: 781 KLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANP 840
Query: 839 HRNSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWD 898
H +++PS AT++IVVCV FLV M++LG+ RI + HRR K+ ++ WD
Sbjct: 841 HPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTM------RDQDTGKENEMDWD 894
Query: 899 DSALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDE 945
DSALTI VNPME+Y+++ S + ++E+E+S D E D +S E
Sbjct: 895 DSALTITVNPMETYEDQHS--SEEEEEEEEEEESEDGEEEDDITSAE 939
>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
Length = 981
Score = 1016 bits (2626), Expect = 0.0
Identities = 495/957 (51%), Positives = 677/957 (70%), Gaps = 41/957 (4%)
Query: 8 LLLASLLASCS--CNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYA--- 62
LLLA LL + NKHKPW+E Y GIV ENDNTVLL+PPL ALDKDAPLR+A
Sbjct: 15 LLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAESF 74
Query: 63 -------GEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCG 115
GEICGF++HG VPF+AV++DK+TGEG+IR+KE +DCE QK+++FTIQAYDCG
Sbjct: 75 EVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCG 134
Query: 116 EGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSP 175
+GPDG N KKSHKATVH++VNDVNE+APVF E+ Y+A V EGK YD ILRVEA+D DCSP
Sbjct: 135 KGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSP 194
Query: 176 QYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVE 235
Q+SQIC YEI+TP+ PF +D DG I+NTEKL Y E YK TVTAYDCGKKRA +D V+
Sbjct: 195 QFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVK 254
Query: 236 IQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGC 295
I +KPTC P WQGWN RIEY PG G+LA+FP I LETCDEP+ ++QAT+EL+TSH+ KGC
Sbjct: 255 ISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGC 314
Query: 296 DRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVP 355
DRD YSE++L +LCGAA G +LLP P + NWT GL DS ++ FNGTQAV++P
Sbjct: 315 DRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIP 374
Query: 356 LGGPSGLGSGPQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVH 415
G S S + FT+S WM+HG K +ETI+C++ + + HYSL VH
Sbjct: 375 DGVVS-------VSPKEPFTISVWMRHGPFGRK----KETILCSSDKTDMNRHHYSLYVH 423
Query: 416 GCRIAFLYW--PLLESA-RPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPAL 472
GCR+ FL+ P E RP +F WKL QVCD+EWHHY LN+EFP+VTLY DG S +P
Sbjct: 424 GCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFS 483
Query: 473 IHDNGLIHPPRREPALMIGACWTEEKNKEKEKGDNSTD----TTQGDPLSIHHYFHGYLA 528
+ ++ +HP + E L++GACW E E DN T+ + G L + +F G LA
Sbjct: 484 VTEDYPLHPSKIETQLVVGACWQEFSGVE---NDNETEPVTVASAGGDLHMTQFFRGNLA 540
Query: 529 GFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNH 588
G ++RSG+L ++VI+CLY C+EGLD + E G+G+++ +PSQ +LTLEG+D+ +
Sbjct: 541 GLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDK 600
Query: 589 ALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGT 648
A+QH++Y+N+ +F TPG+R L++T+ +KCF+E +C+S+P V+GYV+VLQP+ P+I LSG
Sbjct: 601 AMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGV 660
Query: 649 AHFARPAVDFEGTNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGC 708
HFAR A +FE + GV LFP+L+I +I+ +VE + D + TV ++ +S+EIVH+LD C
Sbjct: 661 HHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTC 720
Query: 709 EISLVGDDLDPERESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLR 768
E+++ G++L+ E+ESL +D LQQ+G+E++++ +T GV+++ YEE+L RYR
Sbjct: 721 EVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNW 780
Query: 769 HGAALYTRKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPP 828
H +L RKF+L CSE+NGRY SNEF VEVNV+H+ N + H +H+ + QF+H H+
Sbjct: 781 HARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFV 840
Query: 829 EMAGHSLASSHRNSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASS 888
+++GH+LA+ H +++PS AT++IVVCV FLV M++LG+ RI + HRR
Sbjct: 841 DLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTM------RDQD 894
Query: 889 DPKDPDLFWDDSALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDE 945
K+ ++ WDDSALTI VNPME+Y+++ S + ++E+E+S D E D +S E
Sbjct: 895 TGKENEMDWDDSALTITVNPMETYEDQHS--SEEEEEEEEEEESEDGEEEDDITSAE 949
>gi|209364544 calsyntenin 2 [Homo sapiens]
Length = 955
Score = 892 bits (2306), Expect = 0.0
Identities = 449/930 (48%), Positives = 617/930 (66%), Gaps = 49/930 (5%)
Query: 21 KANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAV 80
K NKHKPWIE Y G++ EN++TV+L+PPL ALDKDAP+ +AGEIC F++HG +PFEAV
Sbjct: 36 KVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAV 95
Query: 81 ILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNE 140
+L+K +GEG +RAK P+DCE QKE+TF IQAYDCG GP KKSHKA VH++V DVNE
Sbjct: 96 VLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDVNE 155
Query: 141 FAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNI 200
FAP F E Y+A VTEGK+YD IL+VEAID DCSPQYSQIC YEI+T + PF ID +GNI
Sbjct: 156 FAPTFKEPAYKAVVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNI 215
Query: 201 ENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAG 260
NTEKL Y + Y+ VTAYDCG+K AA D V++ VKP CKP WQ W KRIEY PG+G
Sbjct: 216 RNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPGSG 275
Query: 261 SLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLP 320
S+ LFP I LETCD + ++Q ELQT+++ KGCDR+ YSE++L+KLCGA++G +DLLP
Sbjct: 276 SMPLFPSIHLETCDGAVSSLQIVTELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLP 335
Query: 321 MPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPSGLGSGPQDSLSDHFTLSFWM 380
P NWTAGL V S +I+ F+G Q +VP G +L+D FT++ WM
Sbjct: 336 SPSAATNWTAGLLV---DSSEMIFKFDGRQGAKVPDGIVP-------KNLTDQFTITMWM 385
Query: 381 KHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYWPLLESA---RPVKFLW 437
KHG +P + E+ETI+CN+ + E HY+L VH CR+ FL + A RP +F W
Sbjct: 386 KHGPSPGV-RAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADTFRPAEFHW 444
Query: 438 KLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIHPPRREPALMIGACWTEE 497
KL+Q+CD EWH+Y +N+EFP VTLY DG +++P L+ ++ IHP L +GACW
Sbjct: 445 KLDQICDKEWHYYVINVEFPVVTLYMDGATYEPYLVTNDWPIHPSHIAMQLTVGACW--- 501
Query: 498 KNKEKEKGDNSTDTTQGDPLSIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRD 557
+G T +FHG LA ++R G++ES++VI CL AC+EGLD
Sbjct: 502 ------QGGEVTKP------QFAQFFHGSLASLTIRPGKMESQKVISCLQACKEGLDINS 549
Query: 558 FESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKC 617
ESLG+G+K H NPSQS+L +EGDD+ N ALQ V+Y+N+ +F T GVR L++++ V+C
Sbjct: 550 LESLGQGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLKVSSKVQC 609
Query: 618 FSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFEGTNGVPLFPDLQITCSIS 677
F E+ C+SIPEV+ YV+VLQ P+I L GT HF RPA FE GV LFPD++I + +
Sbjct: 610 FGEDVCISIPEVDAYVMVLQAIEPRITLRGTDHFWRPAAQFESARGVTLFPDIKIVSTFA 669
Query: 678 HQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDTTSLQQRGLE 737
+ EA D + T + + +E++HNLD C+I ++G DLDP +E L L+ + L QR L+
Sbjct: 670 -KTEAPGDV--KTTDPKSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSELHQRHLD 726
Query: 738 LTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRLSCSEMNGRYSSNEFIVE 797
TN++A +I GV S++ YE++L RYR A+L R+FR+ CSE+NGRY+SNEF +E
Sbjct: 727 ATNSTAGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTSNEFNLE 786
Query: 798 VNVLHS--MNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHRNSMIPSAATLIIVVC 855
V++LH ++ H +H++ FL H P S +S +S++PS AT++I++
Sbjct: 787 VSILHEDQVSDKEHVNHLIVQPPFLQSVHHP------ESRSSIQHSSVVPSIATVVIIIS 840
Query: 856 VGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDSALTIIVNPMESYQNR 915
V LV +V +G+ R+ H+ + K+ ++ WDDSALTI VNPME ++
Sbjct: 841 VCMLVFVVAMGVYRVRIAHQHFIQE------TEAAKESEMDWDDSALTITVNPMEKHEGP 894
Query: 916 QSCVTGAVGGQQEDEDSSDSEVADSPSSDE 945
G + E+E+ ++ E++ S SD+
Sbjct: 895 GH---GEDETEGEEEEEAEEEMSSSSGSDD 921
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 63.9 bits (154), Expect = 7e-10
Identities = 66/228 (28%), Positives = 97/228 (42%), Gaps = 20/228 (8%)
Query: 7 PLLLASLLASCSCNKANKHKPWIE-AEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
P L A+ + + + N H P E A+Y+ + EN L A D DAP
Sbjct: 411 PRLSATTMVAVTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPN----- 465
Query: 66 CGFRLHGSGVPFE----AVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGA 121
R G P A + GLI VD E + + ++A D G+ P
Sbjct: 466 ANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPG-- 523
Query: 122 NTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQI 180
+S VH+ V D N+ AP F E+ Y A V E + + +LRV A D D + +
Sbjct: 524 --PRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRD--KDANGL 579
Query: 181 CYYEILTPNT--PFLIDN-DGNIENTEKLQYSGERLYKFTVTAYDCGK 225
+Y I++ N+ F ID+ G I+ L + ER Y + A D G+
Sbjct: 580 VHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGR 627
Score = 60.5 bits (145), Expect = 7e-09
Identities = 45/159 (28%), Positives = 74/159 (46%), Gaps = 9/159 (5%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D TGE I+ P+D EA++E+ I+A D G P NT ++V D+N+
Sbjct: 595 IDSLTGE--IQVVAPLDFEAEREYALRIRAQDAGRPPLSNNT-----GLASIQVVDINDH 647
Query: 142 APVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDN-DGN 199
P+FV ++ +V E L ++ ++A+D D + P+TPF+I++ G
Sbjct: 648 IPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGW 707
Query: 200 IENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
+ + L Y F V A D G + A V + V
Sbjct: 708 VSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTV 746
Score = 50.4 bits (119), Expect = 8e-06
Identities = 63/224 (28%), Positives = 95/224 (42%), Gaps = 25/224 (11%)
Query: 7 PLLLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
PL + LAS N H P ++ +Q V+EN + A+D D GE
Sbjct: 629 PLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADH-----GEN 683
Query: 66 CGFRLHGSGV-PFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTK 124
+GV P +++ ATG + P+D E+ + + F ++A D G P A+
Sbjct: 684 ARLEYSLTGVAPDTPFVINSATG--WVSVSGPLDRESVEHYFFGVEARDHGSPPLSAS-- 739
Query: 125 KSHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYY 183
A+V V V DVN+ P F + Y + E + ++ V A+D D + S Y
Sbjct: 740 ----ASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAIS----Y 791
Query: 184 EILTPNT--PFLIDNDGNIENTE---KLQYSGERLYKFTVTAYD 222
+I NT F I G + L Y ER +K +TA D
Sbjct: 792 QITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASD 835
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/235 (24%), Positives = 92/235 (39%), Gaps = 20/235 (8%)
Query: 7 PLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNP-PLFALDKDAPLRYAGEI 65
P L AS + + N ++P + + + D V + + A+D+DA + +I
Sbjct: 734 PPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQI 793
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
G G + G GL+ P+D + ++ + A D
Sbjct: 794 TG------GNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASD--------RALH 839
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEI 185
H VH+ + D N PVF Y +V E + + V + D + ++I Y +
Sbjct: 840 DH-CYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITY--L 896
Query: 186 LTPNTP-FLIDND-GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
L N P F ID D G I L Y + Y +TA D G + AD VE+ V
Sbjct: 897 LEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMV 951
Score = 47.8 bits (112), Expect = 5e-05
Identities = 60/227 (26%), Positives = 91/227 (40%), Gaps = 22/227 (9%)
Query: 22 ANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEIC-GFRLHGSGVPFEAV 80
AN+H + + YQ +V EN+ + A D DA AG + + E
Sbjct: 319 ANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAG--EAGRLVYSLAALMNSRSLELF 376
Query: 81 ILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNE 140
+D +G LIR +D E+ + H + A D G A T V V V D N+
Sbjct: 377 SIDPQSG--LIRTAAALDRESMERHYLRVTAQDHGSPRLSATTM------VAVTVADRND 428
Query: 141 FAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTP-------NTPF 192
+PVF + YR + E + IL++ A DGD P + Y + P F
Sbjct: 429 HSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNAN--LRYRFVGPPAARAAAAAAF 486
Query: 193 LID-NDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
ID G I + ++ Y+ V A D G++ A V + +
Sbjct: 487 EIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHI 533
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 63/154 (40%), Gaps = 9/154 (5%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G I + P+D E Q +T I A D G +K+ V V VNDVN+ AP FV
Sbjct: 911 GAITLQAPLDYEDQVTYTLAITARDNGI------PQKADTTYVEVMVNDVNDNAPQFVAS 964
Query: 149 LYRAAVTE-GKLYDRILRVEAIDGDCSPQ-YSQICYYEILTPNTPFLID-NDGNIENTEK 205
Y V+E + +L++ A D D Q + + F I+ G + +
Sbjct: 965 HYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRR 1024
Query: 206 LQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVK 239
L +Y+ T A D G +++ V+
Sbjct: 1025 LDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQ 1058
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/206 (24%), Positives = 82/206 (39%), Gaps = 18/206 (8%)
Query: 20 NKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFE 78
N N + P ++ + Y G+V E+ + A D+DA G + +G +
Sbjct: 952 NDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHAN--GRVQYTFQNGEDGDGD 1009
Query: 79 AVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDV 138
I + G++R +D EA + T A D G P ++ V V DV
Sbjct: 1010 FTIEPTS---GIVRTVRRLDREAVSVYELTAYAVDRGVPP------LRTPVSIQVMVQDV 1060
Query: 139 NEFAPVFVERLYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQICYYEILTPNTPFLIDND 197
N+ APVF + V E + ++ ++ A+D D P + Y+I+ N P L D
Sbjct: 1061 NDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGP--NAHIMYQIVEGNIPELFQMD 1118
Query: 198 ---GNIENTEKLQYSGERLYKFTVTA 220
G + L Y + Y V A
Sbjct: 1119 IFSGELTALIDLDYEARQEYVIVVQA 1144
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/212 (31%), Positives = 93/212 (43%), Gaps = 22/212 (10%)
Query: 23 NKHKPWIEA-EYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSG-VPFEAV 80
N H P E EY+ + EN + A D DAP I L GSG P E
Sbjct: 283 NDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPN--ANILYRLLEGSGGSPSEVF 340
Query: 81 ILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNE 140
+D +G +IR + PVD E + + T++A D G P +S A V + V D N+
Sbjct: 341 EIDPRSG--VIRTRGPVDREEVESYQLTVEASDQGRDPG----PRSTTAAVFLSVEDDND 394
Query: 141 FAPVFVERLY----RAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT--PFLI 194
AP F E+ Y R VT G +LRV A D D + + +Y I++ N F +
Sbjct: 395 NAPQFSEKRYVVQVREDVTPGA---PVLRVTASDRDKGS--NAVVHYSIMSGNARGQFYL 449
Query: 195 D-NDGNIENTEKLQYSGERLYKFTVTAYDCGK 225
D G ++ L Y + Y V A D G+
Sbjct: 450 DAQTGALDVVSPLDYETTKEYTLRVRAQDGGR 481
Score = 53.9 bits (128), Expect = 7e-07
Identities = 46/152 (30%), Positives = 65/152 (42%), Gaps = 7/152 (4%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G + P+D E KE+T ++A D G P + V V+V D+N+ AP+FV
Sbjct: 454 GALDVVSPLDYETTKEYTLRVRAQDGGRPP-----LSNVSGLVTVQVLDINDNAPIFVST 508
Query: 149 LYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDN-DGNIENTEKL 206
++A V E L +L V+AID D + + PF I+N G I +L
Sbjct: 509 PFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAEL 568
Query: 207 QYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
Y F V A D G A V + V
Sbjct: 569 DREEVDFYSFGVEARDHGTPALTASASVSVTV 600
Score = 50.4 bits (119), Expect = 8e-06
Identities = 44/151 (29%), Positives = 69/151 (45%), Gaps = 17/151 (11%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
LD TG + E +D E + H F + A D G ++S AT+ + V D N+
Sbjct: 234 LDPVTGA--VTTAEELDRETKSTHVFRVTAQDHGM------PRRSALATLTILVTDTNDH 285
Query: 142 APVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEIL-----TPNTPFLID 195
PVF ++ Y+ ++ E ++ +L V A DGD P + + Y +L +P+ F ID
Sbjct: 286 DPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANIL--YRLLEGSGGSPSEVFEID 343
Query: 196 -NDGNIENTEKLQYSGERLYKFTVTAYDCGK 225
G I + Y+ TV A D G+
Sbjct: 344 PRSGVIRTRGPVDREEVESYQLTVEASDQGR 374
Score = 47.0 bits (110), Expect = 9e-05
Identities = 56/235 (23%), Positives = 90/235 (38%), Gaps = 20/235 (8%)
Query: 7 PLLLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
P L AS S + N + P + + EY + E+ + A+D+DA +I
Sbjct: 588 PALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQI 647
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
SG + +G GL+ P+D + ++++ + A D +
Sbjct: 648 T------SGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASD---------GTR 692
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTEGK-LYDRILRVEAIDGDCSPQYSQICYYE 184
A + V V D N PVF Y V E + ++ + A D D + E
Sbjct: 693 QDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFME 752
Query: 185 ILTPNTPFLIDND-GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
P F ID D G + +L Y + Y +TA D G + +D +EI V
Sbjct: 753 DSIPQ--FRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILV 805
Score = 45.4 bits (106), Expect = 2e-04
Identities = 67/248 (27%), Positives = 102/248 (41%), Gaps = 24/248 (9%)
Query: 7 PLLLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
PL S L + N + P ++ +Q V+E+ L + A+D DA E
Sbjct: 483 PLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLE- 541
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
+RL G G F I + G G I +D E ++F ++A D G A+
Sbjct: 542 --YRLAGVGHDFPFTINN---GTGWISVAAELDREEVDFYSFGVEARDHGTPALTAS--- 593
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYYE 184
A+V V V DVN+ P F + Y + E + ++ V A+D D + Y+
Sbjct: 594 ---ASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA----HSVITYQ 646
Query: 185 ILTPNT--PFLIDND---GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVK 239
I + NT F I + G + L Y ER Y VTA D G ++ V +
Sbjct: 647 ITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASD-GTRQDTAQIVVNVTDA 705
Query: 240 PTCKPSWQ 247
T +P +Q
Sbjct: 706 NTHRPVFQ 713
Score = 38.1 bits (87), Expect = 0.040
Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 30/160 (18%)
Query: 22 ANKHKPWIEAEYQGIVMENDN----TVLLNPPLFALDKD----APLRYAGEICGFRLHGS 73
AN H+P ++ + + + D TV+L + A D+D A + Y E
Sbjct: 705 ANTHRPVFQSSHYTVNVNEDRPAGTTVVL---ISATDEDTGENARITYFME--------D 753
Query: 74 GVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHV 133
+P + D G + + +D E Q +T I A D G +KS + +
Sbjct: 754 SIPQFRIDADT----GAVTTQAELDYEDQVSYTLAITARDNGI------PQKSDTTYLEI 803
Query: 134 RVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGD 172
VNDVN+ AP F+ Y+ +V E + +L++ A D D
Sbjct: 804 LVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRD 843
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 56.2 bits (134), Expect = 1e-07
Identities = 52/169 (30%), Positives = 79/169 (46%), Gaps = 18/169 (10%)
Query: 81 ILDKATGE-------GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHV 133
++D A G+ G+I+ ++P+D E Q +T +++A D G + + TV V
Sbjct: 3164 LIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVD-----QGLPRRLTATGTVIV 3218
Query: 134 RVNDVNEFAPVFVERLYRAAVTEGKLY-DRILRVEAIDGDCSPQYSQICYYEILTPNT-- 190
V D+N+ PVF R Y A V+E L +L+V A D + + Y I++ N
Sbjct: 3219 SVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDI--EANAEITYSIISGNEHG 3276
Query: 191 PFLIDN-DGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
F ID+ G + E L Y Y TV A D G +D A V + V
Sbjct: 3277 KFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNV 3325
Score = 53.5 bits (127), Expect = 9e-07
Identities = 50/161 (31%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D TG I E +D E+ E+ T++A DG S ATV+V V D+N+
Sbjct: 3280 IDSKTGAVFII--ENLDYESSHEYYLTVEA------TDGGTPSLSDVATVNVNVTDINDN 3331
Query: 142 APVFVERLYRAAVTEGKLYDR-ILRVEAIDGDCSPQYSQICYYEILTPN--TPFLIDN-D 197
PVF + Y ++E + ++ ++ V A D D P S I +Y I+ N + F ID
Sbjct: 3332 TPVFSQDTYTTVISEDAVLEQSVITVMADDAD-GPSNSHI-HYSIIDGNQGSSFTIDPVR 3389
Query: 198 GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
G ++ T+ L Y TV A D G + V I V
Sbjct: 3390 GEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDV 3430
Score = 51.2 bits (121), Expect = 5e-06
Identities = 46/184 (25%), Positives = 81/184 (44%), Gaps = 13/184 (7%)
Query: 20 NKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEA 79
+ N H P + + +N + + +F D + G++ + + G G
Sbjct: 707 HSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLV-YAVSG-GNEDSC 764
Query: 80 VILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVN 139
++D TG +++ P+D E ++T I YD G +K+ +HV V D N
Sbjct: 765 FMIDMETG--MLKILSPLDRETTDKYTLNITVYDLG------IPQKAAWRLLHVVVVDAN 816
Query: 140 EFAPVFVERLYRAAVTEGK-LYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDG 198
+ P F++ Y V+E K ++ I++VEA D D P + Y I+T F ID+
Sbjct: 817 DNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGP--NGHVTYSIVTDTDTFSIDSVT 874
Query: 199 NIEN 202
+ N
Sbjct: 875 GVVN 878
Score = 49.3 bits (116), Expect = 2e-05
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 10/154 (6%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYD-CGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE 147
G++ P+D E Q EH+ I+A D E P +T V V + DVN+ P F+
Sbjct: 875 GVVNIARPLDRELQHEHSLKIEARDQAREEPQLFST-----VVVKVSLEDVNDNPPTFIP 929
Query: 148 RLYRAAVTEGKLYDRILR-VEAIDGDCSPQYSQICYYEILTPNTPFLIDN-DGNIENTEK 205
YR V E ++ +EA D D Q Q+ Y + F +D G + ++
Sbjct: 930 PNYRVKVREDLPEGTVIMWLEAHDPDLG-QSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQ 988
Query: 206 LQYSGERLYKFTVTAYDCGKK-RAADDAEVEIQV 238
L + +++Y TV A D GK + VE++V
Sbjct: 989 LDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEV 1022
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/169 (25%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 74 GVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHV 133
G PF ++ TG +I P+D EA + +I+A D G + V +
Sbjct: 2221 GDPFSQFTINFNTG--VINVIAPLDFEAHPAYKLSIRATDSLTGAHA-------EVFVDI 2271
Query: 134 RVNDVNEFAPVFVERLYRAAVTEGKLY-DRILRVEAIDGDCSPQ--YSQICYYEILTPNT 190
V+D+N+ PVF ++ Y ++E + +++V A D D P S + +
Sbjct: 2272 IVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHD 2331
Query: 191 PFLIDND-GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
F +D+ G I L Y R + V A D G + D V + V
Sbjct: 2332 HFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDV 2380
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/160 (25%), Positives = 74/160 (46%), Gaps = 12/160 (7%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D GE ++ + +D E +T T+QA D G P + + TV++ V+DVN+
Sbjct: 3385 IDPVRGE--VKVTKLLDRETISGYTLTVQASDNGSPP------RVNTTTVNIDVSDVNDN 3436
Query: 142 APVFVERLYRAAVTEGK-LYDRILRVEAIDGDCSPQYSQICYYEILTPN--TPFLIDNDG 198
APVF Y + E K + +L++ D D S ++ I+T N F ++ G
Sbjct: 3437 APVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPF-FFTIVTGNDEKAFEVNPQG 3495
Query: 199 NIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
+ + ++ + Y V D GK + + ++I+V
Sbjct: 3496 VLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 45.1 bits (105), Expect = 3e-04
Identities = 54/219 (24%), Positives = 91/219 (41%), Gaps = 16/219 (7%)
Query: 9 LLASLLASCSCNKANKHKPWIEAE-YQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICG 67
L ++ + + N P AE Y+G V E+D + L D D+ ++
Sbjct: 2898 LSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSE-EINRQVTY 2956
Query: 68 FRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSH 127
F G P ++ E + K+P+D E + + TI A D S
Sbjct: 2957 FITGGD--PLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATD---------GTFSS 3005
Query: 128 KATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-ILRVEAIDGDCSPQYSQICYYEIL 186
KA V V+V D N+ +PV + LY + E L + I+++ A D D ++I Y +
Sbjct: 3006 KAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSN-AEITYTLLG 3064
Query: 187 TPNTPFLIDND-GNIENTEKLQYSGERLYKFTVTAYDCG 224
+ F ++ D G ++ + L + +Y V A D G
Sbjct: 3065 SGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGG 3103
Score = 43.1 bits (100), Expect = 0.001
Identities = 64/227 (28%), Positives = 96/227 (42%), Gaps = 36/227 (15%)
Query: 28 WIEAEYQGIVMEND--NTVLL---NPPLFA----LDKDAPLRYAGEICGFRLHGSGVPFE 78
+++AEY G++ E+ N+V+L N PL DKD+ I +H
Sbjct: 1765 FMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVH------T 1818
Query: 79 AVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDV 138
+D +TG I +D E FT+Q +D G + A V V V D+
Sbjct: 1819 YFAIDSSTGA--IHTVLSLDYEETSIFHFTVQVHDMGT----PRLFAEYAANVTVHVIDI 1872
Query: 139 NEFAPVFVERLYRAAVTEGKLYD-RILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND 197
N+ PVF + LY A++ +++ V A D D S +SQ+ Y I N D
Sbjct: 1873 NDCPPVFAKPLYEASLLLPTYKGVKVITVNATDAD-SSAFSQL-IYSITEGNIGEKFSMD 1930
Query: 198 G-----NIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVK 239
++NT +L+ Y+ TV A D R A V+I VK
Sbjct: 1931 YKTGALTVQNTTQLR----SRYELTVRASD---GRFAGLTSVKINVK 1970
Score = 40.4 bits (93), Expect = 0.008
Identities = 40/152 (26%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
GLI +D E ++HT ++A D G S V V V D+N+ P+F ++
Sbjct: 2340 GLISLLRTLDYEQSRQHTIFVRAVD------GGMPTLSSDVIVTVDVTDLNDNPPLFEQQ 2393
Query: 149 LYRAAVTEGKLYDRILR-VEAIDGDCSPQYSQICYYEILTPN--TPFLIDNDGNIENTEK 205
+Y A ++E + + V+A D D S Y IL+ N F+ID+ I
Sbjct: 2394 IYEARISEHAPHGHFVTCVKAYDADSSD--IDKLQYSILSGNDHKHFVIDSATGIITLSN 2451
Query: 206 L-QYSGERLYKFTVTAYDCGKKRAADDAEVEI 236
L +++ + Y ++ D G R++ V +
Sbjct: 2452 LHRHALKPFYSLNLSVSD-GVFRSSTQVHVTV 2482
Score = 40.4 bits (93), Expect = 0.008
Identities = 51/174 (29%), Positives = 77/174 (44%), Gaps = 16/174 (9%)
Query: 56 DAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCG 115
DA +R EI + L GSG E L+ TGE ++ P+D E Q + ++A D G
Sbjct: 3049 DADIRSNAEIT-YTLLGSGA--EKFKLNPDTGE--LKTSTPLDREEQAVYHLLVRATDGG 3103
Query: 116 EGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRIL-RVEAIDGDCS 174
+ +A++ + + DVN+ AP F Y V E +L RV+A D D
Sbjct: 3104 G--------RFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAG 3155
Query: 175 PQYSQICYYEILTPNTPFLIDNDGNIENTEK-LQYSGERLYKFTVTAYDCGKKR 227
+I Y I + + F I+ I EK L + +Y ++ A D G R
Sbjct: 3156 LN-RKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPR 3208
Score = 38.9 bits (89), Expect = 0.023
Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 11/129 (8%)
Query: 100 EAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-K 158
E + +T ++A + NT + V V+V D N+ P+F Y ++ E
Sbjct: 111 EVKDHYTLIVKALE-------KNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTA 163
Query: 159 LYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLI-DNDGNIENTEKLQYSGERLYKFT 217
+ I RV A D D YY F I G I T +L Y +LY+
Sbjct: 164 IRTSIARVSATDADIGTNGE--FYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEME 221
Query: 218 VTAYDCGKK 226
+ A D G K
Sbjct: 222 ILAADRGMK 230
Score = 38.9 bits (89), Expect = 0.023
Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 20/223 (8%)
Query: 9 LLASLLASCSCNKANKHKPWIEAE-YQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICG 67
++AS+ S AN + P E+ Y+ ++EN + A D D+ G++
Sbjct: 2789 MVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTN--GQVMY 2846
Query: 68 FRLHGSGVP-FEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKS 126
V E+ ++ TG I + +D E + + + A D GE + S
Sbjct: 2847 SLDQSQSVEVIESFAINMETG--WITTLKELDHEKRDNYQIKVVASDHGE-----KIQLS 2899
Query: 127 HKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRV-EAIDGDCSPQYSQICYYEI 185
A V V V DVN+ P F +Y+ V+E ++ + D D Q+ Y+
Sbjct: 2900 STAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYF-- 2957
Query: 186 LTPNTPF------LIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
+T P I N+ + + L Y T+TA D
Sbjct: 2958 ITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATD 3000
Score = 38.1 bits (87), Expect = 0.040
Identities = 39/166 (23%), Positives = 65/166 (39%), Gaps = 20/166 (12%)
Query: 83 DKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFA 142
D G G I +P+D E + + T++A DG T + V ++V D N+
Sbjct: 1403 DVDKGTGTIIVAKPLDAEQKSNYNLTVEA------TDGTTTILTQ---VFIKVIDTNDHR 1453
Query: 143 PVFVERLYRAAVTEGKLYD-RILRVEAIDGDCSPQYSQICYYEILTPNTP-----FLID- 195
P F Y + E + IL++ A+D D Y + + P F +D
Sbjct: 1454 PQFSTSKYEVVIPEDTAPETEILQISAVDQD----EKNKLIYTLQSSRDPLSLKKFRLDP 1509
Query: 196 NDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPT 241
G++ +EKL + + TV D + A + + V T
Sbjct: 1510 ATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDT 1555
Score = 32.3 bits (72), Expect = 2.2
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 4/119 (3%)
Query: 131 VHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILR-VEAIDGDCSPQYSQICYYEILTPN 189
V V V D N+ APVFV Y A V ++R V A+D D S + ++ YY + +
Sbjct: 2067 VKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRD-SGRNGEVHYY-LKEHH 2124
Query: 190 TPFLIDNDGNIENTEKLQYSG-ERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQ 247
F I G I ++ + + Y TV A D G + + V I V P ++
Sbjct: 2125 EHFQIGPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFE 2183
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 25/213 (11%)
Query: 40 NDNTVLLNPPLFAL--DKDAPL-----------RYAGEICGFRLHGSGVPFEAVILDKAT 86
NDN + P + L ++DA + R A + ++L G G L
Sbjct: 681 NDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTG-GNTRNRFALSSQR 739
Query: 87 GEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFV 146
G GLI P+D + ++++ + A D +SH A V + V D N PVF
Sbjct: 740 GGGLITLALPLDYKQEQQYVLAVTASD---------GTRSHTAHVLINVTDANTHRPVFQ 790
Query: 147 ERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND-GNIENTEK 205
Y +V+E + + + + + + + ++I Y I P F ID D G + +
Sbjct: 791 SSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYV-IQDPVPQFRIDPDSGTMYTMME 849
Query: 206 LQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
L Y + Y T+ A D G + +D +EI +
Sbjct: 850 LDYENQVAYTLTIMAQDNGIPQKSDTTTLEILI 882
Score = 54.3 bits (129), Expect = 5e-07
Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 23 NKHKPWIE-AEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVI 81
N H P E +EY+ V EN + A D+D+P+ R G ++
Sbjct: 347 NDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPIN-----ANLRYRVLGGAWDVFQ 401
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
L++++G ++ + +D E E+ ++A D G P S ATV++ V D N+
Sbjct: 402 LNESSG--VVSTRAVLDREEAAEYQLLVEANDQGRNPGPL----SATATVYIEVEDENDN 455
Query: 142 APVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP---FLIDND 197
P F E+ Y V E L +LRV+A D D + +Y IL+ N +L
Sbjct: 456 YPQFSEQNYVVQVPEDVGLNTAVLRVQATDRD--QGQNAAIHYSILSGNVAGQFYLHSLS 513
Query: 198 GNIENTEKLQYSGERLYKFTVTAYDCGK 225
G ++ L + + Y ++ A D G+
Sbjct: 514 GILDVINPLDFEDVQKYSLSIKAQDGGR 541
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/170 (26%), Positives = 73/170 (42%), Gaps = 26/170 (15%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G++ P+D E ++++ +I+A D G P + V V+V DVN+ P+FV
Sbjct: 514 GILDVINPLDFEDVQKYSLSIKAQDGGRPP-----LINSSGVVSVQVLDVNDNEPIFVSS 568
Query: 149 LYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEI------------------LTPN 189
++A V E L ++ ++A+D D S + +++ Y + TP+
Sbjct: 569 PFQATVLENVPLGYPVVHIQAVDAD-SGENARLHYRLVDTASTFLGGGSAGPKNPAPTPD 627
Query: 190 TPFLIDN-DGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
PF I N G I +L Y F V A D G + V I V
Sbjct: 628 FPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITV 677
Score = 42.4 bits (98), Expect = 0.002
Identities = 61/244 (25%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 7 PLLLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLF---ALDKD----AP 58
PL+ +S + S N ++P ++ + +Q V+EN V L P+ A+D D A
Sbjct: 543 PLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLEN---VPLGYPVVHIQAVDADSGENAR 599
Query: 59 LRYAGEICGFRLHGSG-------VPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQA 111
L Y G G P G I +D E + ++F ++A
Sbjct: 600 LHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEA 659
Query: 112 YDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAID 170
D G P ++T +V + V DVN+ PVF + Y + E + +L ++A D
Sbjct: 660 VDHGSPPMSSST------SVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARD 713
Query: 171 GDCSPQYSQICYYEILTPNT--PFLIDND---GNIENTEKLQYSGERLYKFTVTAYDCGK 225
D + + Y++ NT F + + G I L Y E+ Y VTA D +
Sbjct: 714 RDA----NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTR 769
Query: 226 KRAA 229
A
Sbjct: 770 SHTA 773
Score = 39.7 bits (91), Expect = 0.014
Identities = 39/160 (24%), Positives = 67/160 (41%), Gaps = 11/160 (6%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D ATG + +D E ++ H ++A D P A T + V V D N+
Sbjct: 298 IDSATGA--VSTDSVLDRETKETHVLRVKAVDYSTPPRSATTY------ITVLVKDTNDH 349
Query: 142 APVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNI 200
+PVF + YR V E ++ +L + A D D SP + + Y + F ++ +
Sbjct: 350 SPVFEQSEYRERVRENLEVGYEVLTIRASDRD-SPINANLRYRVLGGAWDVFQLNESSGV 408
Query: 201 ENTEKLQYSGERL-YKFTVTAYDCGKKRAADDAEVEIQVK 239
+T + E Y+ V A D G+ A + ++
Sbjct: 409 VSTRAVLDREEAAEYQLLVEANDQGRNPGPLSATATVYIE 448
Score = 38.9 bits (89), Expect = 0.023
Identities = 54/227 (23%), Positives = 82/227 (36%), Gaps = 31/227 (13%)
Query: 22 ANKHKPWIEAEYQGIVMENDNTVLLN-PPLFALDKDAPLRYAGEICGFRLHGSGVPFEAV 80
AN H+P ++ + + + D V + L A D+D G V
Sbjct: 782 ANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDT--------------GENARITYV 827
Query: 81 ILDKAT------GEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVR 134
I D G + +D E Q +T TI A D G +KS T+ +
Sbjct: 828 IQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGI------PQKSDTTTLEIL 881
Query: 135 VNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP-- 191
+ D N+ AP F+ Y+ ++ E IL+V A D D P + ++
Sbjct: 882 ILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDF 941
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
++ G I +L +Y A D G A VEIQV
Sbjct: 942 YIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPL-SASVEIQV 987
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 22/168 (13%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
GL++ K+ +D E ++ +QA D G S ATV++ ++DVN+ +PVF
Sbjct: 3396 GLVKVKKKLDRERVSGYSLLVQAVDSGI------PAMSSTATVNIDISDVNDNSPVFTPA 3449
Query: 149 LYRAAVTEGK-LYDRILRVEAIDGDC---SPQYSQICYYEILTPN--TPFLIDNDGNIEN 202
Y A + E K + IL++ D D P +S + IL+ N F++D G + +
Sbjct: 3450 NYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFS----FSILSGNEEEEFVLDPHGILRS 3505
Query: 203 TEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV------KPTCKP 244
Q++ Y V A D GK + + ++V KPT P
Sbjct: 3506 AVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIP 3553
Score = 54.3 bits (129), Expect = 5e-07
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 23/211 (10%)
Query: 23 NKHKPWIE-AEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVP---FE 78
N +KP E + Y I+ME + A+D D G++ + LH P E
Sbjct: 2808 NDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGAN--GQVT-YSLHSDSQPEKVME 2864
Query: 79 AVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDV 138
A +D TG I + +D E TF++ A D GE ++T A V VRV D+
Sbjct: 2865 AFNIDSNTG--WISTLKDLDHETDPTFTFSVVASDLGEAFSLSST-----ALVSVRVTDI 2917
Query: 139 NEFAPVFVERLYRAAVTEGKLYDRILRV-EAIDGDCSPQYSQICYYEILTPNTP------ 191
N+ APVF + +YR V E ++ V D D S Q+ Y+ +T P
Sbjct: 2918 NDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYH--ITGGNPRGRFAL 2975
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
L+ ++ + L + +Y +TA D
Sbjct: 2976 GLVQSEWKVYVKRPLDREEQDIYFLNITATD 3006
Score = 47.4 bits (111), Expect = 7e-05
Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 18/165 (10%)
Query: 23 NKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVIL 82
NK P + + + D + +N P+ +++ +P G+ + + G PF+ +
Sbjct: 2180 NKAMPVFDKPFYTASVNED--IRMNTPILSINATSP---EGQGIIYIII-DGDPFKQFNI 2233
Query: 83 DKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFA 142
D TG +++ P+D E + TI+A D A T + TV + VNDVN+
Sbjct: 2234 DFDTG--VLKVVSPLDYEVTSAYKLTIRASD-------ALTGARAEVTVDLLVNDVNDNP 2284
Query: 143 PVFVERLYRAAVTEGKLYDR-ILRVEAIDGDCSPQYSQICYYEIL 186
P+F + Y ++E L +L+V +ID D + +++ +Y+I+
Sbjct: 2285 PIFDQPTYNTTLSEASLIGTPVLQVVSIDAD--SENNKMVHYQIV 2327
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 12/143 (8%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D TG+ ++ P+D E + I YD G N +KS + + V D N+
Sbjct: 776 IDMETGQ--LKVLMPMDREHTDLYLLNITIYDLG------NPQKSSWRLLTINVEDANDN 827
Query: 142 APVFVERLYRAAVTEGK-LYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND-GN 199
+PVF++ Y + E + I++VEA D D Y +LT F I++ G
Sbjct: 828 SPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGE--VTYSVLTDTQQFAINSSTGI 885
Query: 200 IENTEKLQYSGERLYKFTVTAYD 222
+ ++L + Y + A D
Sbjct: 886 VYVADQLDRESKANYSLKIEARD 908
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 8/153 (5%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G++ + +D E++ ++ I+A D E + + T+ V ++DVN+ +P F+
Sbjct: 884 GIVYVADQLDRESKANYSLKIEARDKAE----SGQQLFSVVTLKVFLDDVNDCSPAFIPS 939
Query: 149 LYRAAVTEGKLYDRILR-VEAIDGDCSPQYSQICYYEILTPNTPFLIDN-DGNIENTEKL 206
Y V E ++ +E D D Q+ Y + N F ID G I +++L
Sbjct: 940 SYSVKVLEDLPVGTVIAWLETHDPDLG-LGGQVRYSLVNDYNGRFEIDKASGAIRLSKEL 998
Query: 207 QYSGERLYKFTVTAYDCGKKRAADDAE-VEIQV 238
Y ++ Y TV A D G+ + VE++V
Sbjct: 999 DYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEV 1031
Score = 42.7 bits (99), Expect = 0.002
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 129 ATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILT 187
A VH+RV N ++P F + Y A V E +++ V A DGD Y QI Y I
Sbjct: 2480 AQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGD-PGTYGQISYAIIND 2538
Query: 188 -PNTPFLIDNDGNIENTEKL 206
FLID++G + TE+L
Sbjct: 2539 FAKDRFLIDSNGQVITTERL 2558
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 122 NTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQI 180
N + KA V + + D N+ P F + LY A V E + +L V A D D + I
Sbjct: 449 NKEGDLKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKD-KGENGYI 507
Query: 181 CYYEILTPNTPFLIDN-DGNIENTEKLQY-SGERLYKFTVTAYDCGKK-RAADDAEVEIQ 237
Y PF+I+ G I TE+L + S +Y+F V A D G R + V I+
Sbjct: 508 TYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIR 567
Query: 238 V 238
+
Sbjct: 568 I 568
Score = 42.0 bits (97), Expect = 0.003
Identities = 43/154 (27%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G I E +D E K ++A DG S ATV++ + DVN+ P F +
Sbjct: 3291 GGISVSEVLDYELCKRFYLVVEA------KDGGTPALSAVATVNINLTDVNDNPPKFSQD 3344
Query: 149 LYRAAVTEGKLY-DRILRVEAIDGDCSPQYSQICYYEILT--PNTPFLIDND-GNIENTE 204
+Y A ++E L D ++ + A D D P QI ++ I+ + F +D G ++ +
Sbjct: 3345 VYSAVISEDALVGDSVILLIAEDVDSQPN-GQI-HFSIVNGDRDNEFTVDPVLGLVKVKK 3402
Query: 205 KLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
KL Y V A D G + A V I +
Sbjct: 3403 KLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDI 3436
Score = 41.2 bits (95), Expect = 0.005
Identities = 38/164 (23%), Positives = 72/164 (43%), Gaps = 21/164 (12%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G+I ++ +D E + IQA + + ATV++++ D N+ APVF+
Sbjct: 1721 GVITTQKALDYERTSSYQLIIQATNMAG--------MASNATVNIQIVDENDNAPVFLFS 1772
Query: 149 LYRAAVTEGKLYDRILR--------VEAIDGDCSPQYSQICYYEIL--TPNTPFLIDND- 197
Y +++E + I+R + A D D + + + Y+I+ T F +D+
Sbjct: 1773 QYSGSLSEAAPINSIVRSLDNSPLVIRATDADSN--RNALLVYQIVESTAKKFFTVDSST 1830
Query: 198 GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPT 241
G I L + + F V D G + ++ VE+ ++ T
Sbjct: 1831 GAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVT 1874
Score = 40.8 bits (94), Expect = 0.006
Identities = 56/213 (26%), Positives = 87/213 (40%), Gaps = 19/213 (8%)
Query: 30 EAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEG 89
E Y +VMEN + + A D D+ + E +R+ SG P ++ TG
Sbjct: 1150 EPIYYPVVMENSPKDVSVIQIQAEDPDSS---SNEKLTYRIT-SGNPQNFFAINIKTGL- 1204
Query: 90 LIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERL 149
+ +D E Q EH + D G P K V V+V D N+ P F E++
Sbjct: 1205 ITTTSRKLDREQQAEHFLEVTVTDGGPSP------KQSTIWVVVQVLDENDNKPQFPEKV 1258
Query: 150 YRAAVTE---GKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT--PFLIDNDGNIENTE 204
Y+ + E K + I R A D D P Y I+ N F ID + ++
Sbjct: 1259 YQIKLPERDRKKRGEPIYRAFAFDRDEGPNAE--ISYSIVDGNDDGKFFIDPKTGMVSSR 1316
Query: 205 KLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQ 237
K Q++ T+ A D G+ + + A + I+
Sbjct: 1317 K-QFTAGSYDILTIKAVDNGRPQKSSTARLHIE 1348
Score = 40.8 bits (94), Expect = 0.006
Identities = 42/143 (29%), Positives = 68/143 (47%), Gaps = 16/143 (11%)
Query: 86 TGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVF 145
+ GLI +D E + T +++ D G S + VH+ ++DVN+ PVF
Sbjct: 2341 SSSGLILTARMLDHELVQHCTLKVRSIDSGF------PSLSSEVLVHIYISDVNDNPPVF 2394
Query: 146 VERLYRAAVTEGKLYDR---ILRVEAIDGDCSPQYSQICYYEILTPN--TPFLIDN-DGN 199
+ +Y + V+E L R + V+A D D S + ++ Y IL+ N T FL+D+ G
Sbjct: 2395 NQLIYESYVSE--LAPRGHFVTCVQASDAD-SSDFDRL-EYSILSGNDRTSFLMDSKSGV 2450
Query: 200 IENTEKLQYSGERLYKFTVTAYD 222
I + + E LY V+ D
Sbjct: 2451 ITLSNHRKQRMEPLYSLNVSVSD 2473
Score = 40.4 bits (93), Expect = 0.008
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G++ E +D EAQ +H I D E P N A V V V D N+ +P F
Sbjct: 1516 GVLYTAERLDHEAQDKHILNIMVRD-QEFPYRRNL-----ARVIVNVEDANDHSPYFTNP 1569
Query: 149 LYRAAVTE-GKLYDRILRVEAIDGD 172
LY A+V E L +L+V A+D D
Sbjct: 1570 LYEASVFESAALGSAVLQVTALDKD 1594
Score = 37.4 bits (85), Expect = 0.067
Identities = 40/155 (25%), Positives = 60/155 (38%), Gaps = 7/155 (4%)
Query: 86 TGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVF 145
+ G+I ++P+D E Q + +++A D G S TV + V D+N+ PVF
Sbjct: 3182 SSSGIIILEQPLDREQQSSYNISVRATDQSPGQS-----LSSLTTVTITVLDINDNPPVF 3236
Query: 146 VERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID-NDGNIENT 203
R Y V E ++L V A D F I+ G I +
Sbjct: 3237 ERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVS 3296
Query: 204 EKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
E L Y + + V A D G + A V I +
Sbjct: 3297 EVLDYELCKRFYLVVEAKDGGTPALSAVATVNINL 3331
Score = 37.0 bits (84), Expect = 0.088
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 9/153 (5%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G+I A + +D E + T+ A D G P + + V++ V DVN+ AP+ E
Sbjct: 1098 GVITAADILDRETMGSYWLTVYATDRGVVPLYSTIE------VYIEVEDVNDNAPLTSEP 1151
Query: 149 LYRAAVTEGKLYD-RILRVEAIDGDCSPQYSQICYYEILTPNTPFLID-NDGNIENT-EK 205
+Y V E D +++++A D D S P F I+ G I T K
Sbjct: 1152 IYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTTSRK 1211
Query: 206 LQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
L + + VT D G V +QV
Sbjct: 1212 LDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQV 1244
Score = 36.2 bits (82), Expect = 0.15
Identities = 35/120 (29%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Query: 128 KATVHVRVNDVNEFAPVFVERLYRAAV-TEGKLYDRILRVEAIDGDCSPQYSQICYYEIL 186
+ V V + D+N+ +PVFV Y AAV + + I +V AID D P Y +
Sbjct: 2067 RVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGE--VTYVLQ 2124
Query: 187 TPNTPFLID-NDGNIENTEKLQYSGERL-YKFTVTAYDCGKKRAADDAEVEIQVKPTCKP 244
F I+ N GN+ E + Y T+ A D GK + E+ I + P
Sbjct: 2125 DDYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMP 2184
Score = 35.8 bits (81), Expect = 0.20
Identities = 57/219 (26%), Positives = 84/219 (38%), Gaps = 16/219 (7%)
Query: 9 LLASLLASCSCNKANKHKPWIEAE-YQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICG 67
L ++ L S N + P E Y+G V E+D + L D+D
Sbjct: 2904 LSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTS--DVNRQVS 2961
Query: 68 FRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSH 127
+ + G G P L E + K P+D E Q + I A DG +
Sbjct: 2962 YHITG-GNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITA------TDGLFVTQ-- 3012
Query: 128 KATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-ILRVEAIDGDCSPQYSQICYYEIL 186
A V V V+DVN+ +PV + Y A + E ++ IL+V A D D I Y
Sbjct: 3013 -AMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSN-GYIRYSLYG 3070
Query: 187 TPNTPFLID-NDGNIENTEKLQYSGERLYKFTVTAYDCG 224
+ N+ F +D G ++ L +Y A D G
Sbjct: 3071 SGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGG 3109
Score = 34.7 bits (78), Expect = 0.44
Identities = 39/122 (31%), Positives = 53/122 (43%), Gaps = 15/122 (12%)
Query: 104 EHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDR 162
E+ TI A D G K S +V + + VN+ PVF + Y A+V E ++
Sbjct: 2153 EYGVTILAKDGG--------KPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMNTP 2204
Query: 163 ILRVEAIDGDCSPQYSQICYYEI-LTPNTPFLIDND-GNIENTEKLQYSGERLYKFTVTA 220
IL + A SP+ I Y I P F ID D G ++ L Y YK T+ A
Sbjct: 2205 ILSINA----TSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRA 2260
Query: 221 YD 222
D
Sbjct: 2261 SD 2262
Score = 33.9 bits (76), Expect = 0.75
Identities = 53/220 (24%), Positives = 90/220 (40%), Gaps = 23/220 (10%)
Query: 8 LLLASLLASCSCNKANKHKPWIE-AEYQGIVMEN--DNTVLLNPPLFALDKDAPLRYAGE 64
L + + S + N + P + Y ++ E+ N ++L KDA + G
Sbjct: 3008 LFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSA----KDADIGSNGY 3063
Query: 65 ICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTK 124
I + L+GSG LD +GE ++ +D E ++ +A D G
Sbjct: 3064 I-RYSLYGSGN--SEFFLDPESGE--LKTLALLDRERIPVYSLMAKATDGGG-------- 3110
Query: 125 KSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQICYY 183
+ ++ +H+ + DVN+ PVF Y V E +L RV+A+D D ++ Y
Sbjct: 3111 RFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGIN-RKVVYS 3169
Query: 184 EILTPNTPFLIDNDGNIENTEK-LQYSGERLYKFTVTAYD 222
+ F ID+ I E+ L + Y +V A D
Sbjct: 3170 LADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATD 3209
Score = 33.1 bits (74), Expect = 1.3
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 131 VHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPN 189
V ++V D+N+ PVF Y + EG + ++ +V AID D Q+ Y + + +
Sbjct: 2800 VDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGAN-GQVT-YSLHSDS 2857
Query: 190 TP------FLID-NDGNIENTEKLQYSGERLYKFTVTAYDCGK 225
P F ID N G I + L + + + F+V A D G+
Sbjct: 2858 QPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGE 2900
Score = 32.3 bits (72), Expect = 2.2
Identities = 35/155 (22%), Positives = 70/155 (45%), Gaps = 14/155 (9%)
Query: 89 GLIRAKEPVDCEAQKE-HTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE 147
G+I E +D E+ E + F ++A D G + + + V +R+ +VN+ +P+F +
Sbjct: 526 GVISTTEELDFESSPEIYRFIVRASDWG-----SPYRHESEVNVTIRIGNVNDNSPLFEK 580
Query: 148 RLYRAAVT-EGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP---FLIDNDGNIENT 203
+ ++ + + I V AID D ++ Y+I++ N +L + G ++
Sbjct: 581 VACQGVISYDFPVGGHITAVSAIDID----ELELVKYKIISGNELGFFYLNPDSGVLQLK 636
Query: 204 EKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
+ L SG + F + + AD + I V
Sbjct: 637 KSLTNSGIKNGNFALRITATDGENLADPMSINISV 671
Score = 31.6 bits (70), Expect = 3.7
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 2/97 (2%)
Query: 131 VHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPN 189
V+++V D+N+ P+F Y + E L + +V A D D + YY +
Sbjct: 144 VNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSN-GEFYYYFKNKVD 202
Query: 190 TPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKK 226
+ G I + +L Y + Y + A D G K
Sbjct: 203 LFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMK 239
>gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor
[Homo sapiens]
Length = 803
Score = 54.3 bits (129), Expect = 5e-07
Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
Query: 94 KEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAA 153
K P+D E QK + T+ A D G P S A +HV V D N+ APVF + +YR +
Sbjct: 197 KTPLDREKQKSYHLTLTALDFGAPP------LSSTAQIHVLVTDANDNAPVFSQDVYRVS 250
Query: 154 VTEGKLY--DRILRVEAIDGDCSPQYSQICYYEILTPNTPF-LIDNDGNIENTEKLQYSG 210
++E +Y +L+V A D D + + T F L N G I L +
Sbjct: 251 LSE-NVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEE 309
Query: 211 ERLYKFTVTAYDCGKKRAADDAEVEI 236
+ Y + A D G A EVE+
Sbjct: 310 VKEYSIVLEARDGGGMIAQCTVEVEV 335
Score = 39.3 bits (90), Expect = 0.018
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 54 DKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYD 113
DKD+ R+ GE+ +L G VPF+ + + T + + A +D E E+ T+ A D
Sbjct: 371 DKDS--RHNGEVT-CKLEGD-VPFKILTSSRNTYKLVTDAV--LDREQNPEYNITVTATD 424
Query: 114 CGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYD-RILRVEAIDGD 172
G+ P S +++ + + DVN+ APVF + Y V E I +V A D D
Sbjct: 425 RGKPP------LSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPD 478
Query: 173 CSPQYSQICY 182
P Q+ Y
Sbjct: 479 LGPN-GQVSY 487
>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
[Homo sapiens]
Length = 810
Score = 54.3 bits (129), Expect = 5e-07
Identities = 43/147 (29%), Positives = 69/147 (46%), Gaps = 11/147 (7%)
Query: 94 KEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAA 153
++P+D E Q H + A D G+ P T + +RV D N+ APVF + +YR +
Sbjct: 194 EKPLDREHQSSHRLILTAMDGGDPPLSGTTH------IWIRVTDANDNAPVFSQEVYRVS 247
Query: 154 VTEGKLY-DRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID---NDGNIENTEKLQYS 209
+ E + +LRV A D D ++I Y + +P + L + N G+I L +
Sbjct: 248 LQENVPWGTSVLRVMATDQD-EGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFE 306
Query: 210 GERLYKFTVTAYDCGKKRAADDAEVEI 236
Y +V A D G A + ++EI
Sbjct: 307 ETSRYVLSVEAKDGGVHTAHCNVQIEI 333
>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 54.3 bits (129), Expect = 5e-07
Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
Query: 94 KEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAA 153
K P+D E QK + T+ A D G P S A +HV V D N+ APVF + +YR +
Sbjct: 197 KTPLDREKQKSYHLTLTALDFGAPP------LSSTAQIHVLVTDANDNAPVFSQDVYRVS 250
Query: 154 VTEGKLY--DRILRVEAIDGDCSPQYSQICYYEILTPNTPF-LIDNDGNIENTEKLQYSG 210
++E +Y +L+V A D D + + T F L N G I L +
Sbjct: 251 LSE-NVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEE 309
Query: 211 ERLYKFTVTAYDCGKKRAADDAEVEI 236
+ Y + A D G A EVE+
Sbjct: 310 VKEYSIVLEARDGGGMIAQCTVEVEV 335
Score = 39.3 bits (90), Expect = 0.018
Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 54 DKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYD 113
DKD+ R+ GE+ +L G VPF+ + + T + + A +D E E+ T+ A D
Sbjct: 371 DKDS--RHNGEVT-CKLEGD-VPFKILTSSRNTYKLVTDAV--LDREQNPEYNITVTATD 424
Query: 114 CGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYD-RILRVEAIDGD 172
G+ P S +++ + + DVN+ APVF + Y V E I +V A D D
Sbjct: 425 RGKPP------LSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASDPD 478
Query: 173 CSPQYSQICY 182
P Q+ Y
Sbjct: 479 LGPN-GQVSY 487
>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
[Homo sapiens]
Length = 927
Score = 54.3 bits (129), Expect = 5e-07
Identities = 43/147 (29%), Positives = 69/147 (46%), Gaps = 11/147 (7%)
Query: 94 KEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAA 153
++P+D E Q H + A D G+ P T + +RV D N+ APVF + +YR +
Sbjct: 194 EKPLDREHQSSHRLILTAMDGGDPPLSGTTH------IWIRVTDANDNAPVFSQEVYRVS 247
Query: 154 VTEGKLY-DRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID---NDGNIENTEKLQYS 209
+ E + +LRV A D D ++I Y + +P + L + N G+I L +
Sbjct: 248 LQENVPWGTSVLRVMATDQD-EGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFE 306
Query: 210 GERLYKFTVTAYDCGKKRAADDAEVEI 236
Y +V A D G A + ++EI
Sbjct: 307 ETSRYVLSVEAKDGGVHTAHCNVQIEI 333
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 52.8 bits (125), Expect = 2e-06
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 19/215 (8%)
Query: 28 WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATG 87
+I E G+V + + P F +D +Y L G G PF
Sbjct: 430 YIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYK---VNCYLDGEG-PFRLSPYKPYNN 485
Query: 88 EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE 147
E L+ +P+D E Q+ + + A++ +G + K+ + V++ D N+ AP+F++
Sbjct: 486 EYLLETTKPMDYELQQFYEVAVVAWNS----EGFHVKR----VIKVQLLDDNDNAPIFLQ 537
Query: 148 RLYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQICYYEILTPNTP--FLIDN-DGNIENT 203
L + E + L ++ A D D S + Q+ Y+ L P+ P F +D+ G + +
Sbjct: 538 PLIELTIEENNSPNAFLTKLYATDAD-SEERGQVSYF--LGPDAPSYFSLDSVTGILTVS 594
Query: 204 EKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
+L + Y++TV A DCGK A V + V
Sbjct: 595 TQLDREEKEKYRYTVRAVDCGKPPRESVATVALTV 629
Score = 42.7 bits (99), Expect = 0.002
Identities = 49/202 (24%), Positives = 86/202 (42%), Gaps = 17/202 (8%)
Query: 37 VMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEP 96
+ EN++ L+A D D+ R G++ F G P LD TG ++
Sbjct: 544 IEENNSPNAFLTKLYATDADSEER--GQVSYFL--GPDAP-SYFSLDSVTG--ILTVSTQ 596
Query: 97 VDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTE 156
+D E ++++ +T++A DCG+ P + ATV + V D N+ +P F+ + + V E
Sbjct: 597 LDREEKEKYRYTVRAVDCGKPP------RESVATVALTVLDKNDNSPRFINKDFSFFVPE 650
Query: 157 G-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID-NDGNIENTEKLQYSGERLY 214
Y I + D D + ++ + F+ID G + L + Y
Sbjct: 651 NFPGYGEIGVISVTDADAG--RNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSY 708
Query: 215 KFTVTAYDCGKKRAADDAEVEI 236
V A D G+ + A++ I
Sbjct: 709 TLWVEAVDGGEPALSSTAKITI 730
Score = 38.1 bits (87), Expect = 0.040
Identities = 39/148 (26%), Positives = 62/148 (41%), Gaps = 17/148 (11%)
Query: 86 TGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVF 145
TG+G++RAK +D E Q +T ++A D GE S A + + + D+N+ P+
Sbjct: 689 TGKGMLRAKVSLDREQQSSYTLWVEAVDGGE------PALSSTAKITILLLDINDNPPLV 742
Query: 146 V----ERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP----FLID-N 196
+ Y + + V A+D D + + Y I+ P F ID
Sbjct: 743 LFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTG--MNAVIAYSIIGRRGPRPESFRIDPK 800
Query: 197 DGNIENTEKLQYSGERLYKFTVTAYDCG 224
GNI E L + L++ V D G
Sbjct: 801 TGNITLEEALLQTDYGLHRLLVKVSDHG 828
>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
[Homo sapiens]
Length = 871
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 11/136 (8%)
Query: 94 KEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAA 153
++P+D E Q ++ + A D G N +S A + V V DVN+ AP F + YR +
Sbjct: 197 EKPLDREKQSDYRLVLTAVD------GGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRIS 250
Query: 154 VTEGKLYDRIL-RVEAIDGDCSPQYSQICYYEILTP----NTPFLIDNDGNIENTEKLQY 208
V E +L ++ A D D P + Y+ TP N L G + L +
Sbjct: 251 VLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDF 310
Query: 209 SGERLYKFTVTAYDCG 224
E Y+F V A D G
Sbjct: 311 ESENYYEFDVRARDGG 326
Score = 38.1 bits (87), Expect = 0.040
Identities = 37/152 (24%), Positives = 61/152 (40%), Gaps = 17/152 (11%)
Query: 96 PVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVT 155
P+D EA+ + + A D G P S T+ + ++DVN+ P F +R + V
Sbjct: 412 PLDREAKSSYDIMVTASDAGNPP------LSTHRTIFLNISDVNDNPPSFFQRSHEVFVP 465
Query: 156 E-GKLYDRILRVEAIDGDCSPQYSQICYYEILTPN------TPFLIDN--DGNIENTEKL 206
E + D + + A D D + + Y +L P + F+ N G + T
Sbjct: 466 ENNRPGDLLCSLAASDPDSG--LNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSF 523
Query: 207 QYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
Y + +F V A D G + V + V
Sbjct: 524 DYEQTQTLQFEVQARDRGNPPLSSTVTVRLFV 555
>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
[Homo sapiens]
Length = 938
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 11/136 (8%)
Query: 94 KEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAA 153
++P+D E Q ++ + A D G N +S A + V V DVN+ AP F + YR +
Sbjct: 197 EKPLDREKQSDYRLVLTAVD------GGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRIS 250
Query: 154 VTEGKLYDRIL-RVEAIDGDCSPQYSQICYYEILTP----NTPFLIDNDGNIENTEKLQY 208
V E +L ++ A D D P + Y+ TP N L G + L +
Sbjct: 251 VLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDF 310
Query: 209 SGERLYKFTVTAYDCG 224
E Y+F V A D G
Sbjct: 311 ESENYYEFDVRARDGG 326
Score = 38.1 bits (87), Expect = 0.040
Identities = 37/152 (24%), Positives = 61/152 (40%), Gaps = 17/152 (11%)
Query: 96 PVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVT 155
P+D EA+ + + A D G P S T+ + ++DVN+ P F +R + V
Sbjct: 412 PLDREAKSSYDIMVTASDAGNPP------LSTHRTIFLNISDVNDNPPSFFQRSHEVFVP 465
Query: 156 E-GKLYDRILRVEAIDGDCSPQYSQICYYEILTPN------TPFLIDN--DGNIENTEKL 206
E + D + + A D D + + Y +L P + F+ N G + T
Sbjct: 466 ENNRPGDLLCSLAASDPDSG--LNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSF 523
Query: 207 QYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
Y + +F V A D G + V + V
Sbjct: 524 DYEQTQTLQFEVQARDRGNPPLSSTVTVRLFV 555
>gi|16933565 protocadherin 21 precursor [Homo sapiens]
Length = 859
Score = 52.4 bits (124), Expect = 2e-06
Identities = 48/153 (31%), Positives = 71/153 (46%), Gaps = 8/153 (5%)
Query: 22 ANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAV 80
AN P +I+ Y +V E+ + + A+D+D +G + L PF
Sbjct: 128 ANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTG---SGGSVTYFLQNLHSPFA-- 182
Query: 81 ILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNE 140
+D+ +G ++A +D E + H T+ A D G GA+ S TV V V DV +
Sbjct: 183 -VDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQD 241
Query: 141 FAPVFVERLYRAAVTEGKL-YDRILRVEAIDGD 172
APVFV Y V E L +L+V A+DGD
Sbjct: 242 MAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGD 274
Score = 35.0 bits (79), Expect = 0.33
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 131 VHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPN 189
V + V D N+ AP F++ Y A V E I +V A+D D S + + L +
Sbjct: 121 VVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQNL--H 178
Query: 190 TPFLIDNDGNIENTE---KLQYSGERLYKFTVTAYDCG 224
+PF +D + + L Y R + TV A D G
Sbjct: 179 SPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGG 216
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/163 (27%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
Query: 12 SLLASCSCNKANKHKPWI-EAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRL 70
SL+ + + N H P E E+ V EN + + A+D D ++ F +
Sbjct: 148 SLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLI 207
Query: 71 HGSGVPFEAVI-LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKA 129
+ + E+ +D+ +GE IR +D E + T I+A DCGE + T
Sbjct: 208 SQTPLLKESGFRVDRLSGE--IRLSGCLDYETAPQFTLLIRARDCGEPSLSSTT------ 259
Query: 130 TVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGD 172
TVHV V + N P F + Y+ + EG+ +LR+ D D
Sbjct: 260 TVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRD 302
Score = 43.9 bits (102), Expect = 7e-04
Identities = 48/184 (26%), Positives = 82/184 (44%), Gaps = 18/184 (9%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G I PVD E +FT+ +D E G S ++R++DVN+ AP F E+
Sbjct: 114 GRIYVHRPVDREMTP--SFTVY-FDVVERSTGKIVDTS--LIFNIRISDVNDHAPQFPEK 168
Query: 149 LYRAAVTE----GKLYDRILRVEAIDGDCSPQYSQICYYEI----LTPNTPFLIDN-DGN 199
+ V E G+ ++L V+ +D + +P SQ+ Y+ I L + F +D G
Sbjct: 169 EFNITVQENQSAGQPIFQMLAVD-LDEENTPN-SQVLYFLISQTPLLKESGFRVDRLSGE 226
Query: 200 IENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKP--TCKPSWQGWNKRIEYAP 257
I + L Y + + A DCG+ + V + V+ +P++ N +++
Sbjct: 227 IRLSGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPE 286
Query: 258 GAGS 261
G S
Sbjct: 287 GRAS 290
Score = 40.0 bits (92), Expect = 0.010
Identities = 46/201 (22%), Positives = 74/201 (36%), Gaps = 13/201 (6%)
Query: 7 PLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEIC 66
P L ++ + N H+P E + + L D+D+P A
Sbjct: 253 PSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAK 312
Query: 67 GFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYD------CGEGPDG 120
LHG+ + D T EG++ +P+D E + + I + C G
Sbjct: 313 FNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQ 372
Query: 121 ANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQ 179
K + ATV V+V D N+ P F + + EG +L A+D D SQ
Sbjct: 373 PPRKAAASATVSVQVTDAND-PPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD-----SQ 426
Query: 180 ICYYEILTPNTPFLIDNDGNI 200
I Y + P +D + +
Sbjct: 427 IRYELVHDPANWVSVDKNSGV 447
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 51.6 bits (122), Expect = 3e-06
Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 13/158 (8%)
Query: 86 TGEGL---IRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFA 142
+GEG + +K +D E ++ ++ D GE K+ V+V V D+N+
Sbjct: 194 SGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE------PKRRGYLQVNVTVQDINDNP 247
Query: 143 PVFVERLYRAAVTEGKLY-DRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND-GNI 200
PVF Y+A V E + +L+V A D D Y + TPF +D + G I
Sbjct: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNAD--IRYRLQDEGTPFQMDPETGLI 305
Query: 201 ENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
E L + R Y TV A D G AE IQ+
Sbjct: 306 TVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQL 343
Score = 49.3 bits (116), Expect = 2e-05
Identities = 52/183 (28%), Positives = 80/183 (43%), Gaps = 25/183 (13%)
Query: 52 ALDKD----APLRYAGEIC--GFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEH 105
A+DKD +RY+ E+ F LH + E + E L+R +
Sbjct: 1124 AVDKDFGPNGEVRYSFEMVQPDFELHA--ISGEITNTHQFDRESLMRRR------GTAVF 1175
Query: 106 TFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKL-YDRIL 164
+FT+ A D G +ATVHV + D+N+ AP F++ Y+A ++E ++L
Sbjct: 1176 SFTVIATD-----QGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVL 1230
Query: 165 RVEAIDGDCSPQYSQICYYEILTPN--TPFLIDN-DGNIENTEKLQYSGERLYKFTVTAY 221
RV A D D + + +Y I+ N F ID+ G + KL Y Y + A
Sbjct: 1231 RVSASDVD--EGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAV 1288
Query: 222 DCG 224
D G
Sbjct: 1289 DSG 1291
Score = 48.1 bits (113), Expect = 4e-05
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 12/155 (7%)
Query: 86 TGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVF 145
T +G +R +D E +T T+ A D G+ ++T+ V V V D+N+ P+F
Sbjct: 2101 TIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTE------VVVMVLDINDNNPIF 2154
Query: 146 VERLYRAAVTEGKLYDR-ILRVEAIDGDCSPQYSQICYYEILTPNT--PFLIDN-DGNIE 201
+ LY+ + E L I++V A DGD Q+ Y I+ NT F ID+ G I
Sbjct: 2155 AQALYKVEINENTLTGTDIIQVFAADGD-EGTNGQV-RYGIVNGNTNQEFRIDSVTGAIT 2212
Query: 202 NTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEI 236
+ L Y TV A D G D + V I
Sbjct: 2213 VAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
Score = 47.8 bits (112), Expect = 5e-05
Identities = 57/238 (23%), Positives = 98/238 (41%), Gaps = 16/238 (6%)
Query: 7 PLLLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
P L + + + N H P + ++ + E+ + + + A D+DA +
Sbjct: 3067 PPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMN----- 3121
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
G + E I + G++ + +D E ++H TI A D G +
Sbjct: 3122 -GLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAID------GGWVAR 3174
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYYE 184
+ +V V V DVN+ +PVF+ Y V E ++ + A D D S + I Y
Sbjct: 3175 TGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDAD-SGTNAVIAYTV 3233
Query: 185 ILTPNTPFLID-NDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPT 241
+ + F+ID N G I L + ++ Y TV A++ + A V IQ+K T
Sbjct: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGT 3291
Score = 47.0 bits (110), Expect = 9e-05
Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 13/160 (8%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D+ TG+ + +P+D E +++ I+A D G P + K + + V DVN+
Sbjct: 2614 IDQLTGQ--VSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEK------LDITVLDVNDN 2665
Query: 142 APVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPN--TPFLIDN-DG 198
AP+F E + + + E +IL V A+D D P YEI+ N F I++ G
Sbjct: 2666 APIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQ--LDYEIVNGNMENSFSINHATG 2723
Query: 199 NIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
I + L Y T+ + D G + +V I +
Sbjct: 2724 EIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINI 2763
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/162 (26%), Positives = 70/162 (43%), Gaps = 14/162 (8%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D +G+ + K +D EA ++ IQA D G P + T+++ + D N+
Sbjct: 1260 IDSTSGQVTLIGK--LDYEATPAYSLVIQAVDSGTIPLNST------CTLNIDILDENDN 1311
Query: 142 APVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPN---TPFLIDND 197
P F + V E ++ + + V A D D YY I N T + N
Sbjct: 1312 TPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNAD--LYYSITGTNNHGTFSISPNT 1369
Query: 198 GNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVK 239
G+I +KL + + LYK +TA D G+ + V I V+
Sbjct: 1370 GSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVR 1411
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/153 (26%), Positives = 64/153 (41%), Gaps = 10/153 (6%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G I +P+D E + T+QA D G P ++ +TV + + D+N+F PVF
Sbjct: 2209 GAITVAKPLDREKTPTYHLTVQATDRGSTP------RTDTSTVSIVLLDINDFVPVFELS 2262
Query: 149 LYRAAVTE--GKLYDRILRVEAIDGDCSPQYSQICYYEI-LTPNTPFLIDNDGNIENTEK 205
Y V E G L IL+V A D D S++ Y + F + G + T+
Sbjct: 2263 PYSVNVPENLGTLPRTILQVVARDDDRGSN-SKLSYVLFGGNEDNAFTLSASGELGVTQS 2321
Query: 206 LQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
L + + +TA D G + + V
Sbjct: 2322 LDRETKERFVLMITATDSGSPALTGTGTINVIV 2354
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/85 (32%), Positives = 46/85 (54%), Gaps = 11/85 (12%)
Query: 68 FRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSH 127
+RL G PF+ +D TG LI +EP+D EA+++++ T+QA D G +
Sbjct: 287 YRLQDEGTPFQ---MDPETG--LITVREPLDFEARRQYSLTVQAMDRGV------PSLTG 335
Query: 128 KATVHVRVNDVNEFAPVFVERLYRA 152
+A +++ DVN+ PV R + A
Sbjct: 336 RAEALIQLLDVNDNDPVVKFRYFPA 360
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 7/152 (4%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G+++ + +D E+Q + +Q +D + P T A V + + DVN+ P F+
Sbjct: 1998 GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTS---TAQVSIILLDVNDNPPTFLSP 2054
Query: 149 LYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTP-NTPFLIDN-DGNIENTEKL 206
+ + + +A D D P + Y +L P F I DG + T +L
Sbjct: 2055 KLTYIPENTPIDTVVFKAQATDPDSGP--NSYIEYTLLNPLGNKFSIGTIDGEVRLTGEL 2112
Query: 207 QYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
Y TV A D G+ + EV + V
Sbjct: 2113 DREEVSNYTLTVVATDKGQPSLSSSTEVVVMV 2144
Score = 40.0 bits (92), Expect = 0.010
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Query: 50 LFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTI 109
L D D+P G I L G+ V K LI+ +D E + T+
Sbjct: 380 LTVTDADSPAAN-GNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
Query: 110 QAYDCGEGPDGANTK-KSHKATVHVRVNDVNEFAPVFVERLYRAAVT-EGKLYDRILRVE 167
D P GA + +S A++ + VND+N+ PVF +++YR ++ E + +
Sbjct: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGIS 498
Query: 168 AIDGD 172
A DGD
Sbjct: 499 ATDGD 503
Score = 35.4 bits (80), Expect = 0.26
Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 12/154 (7%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G+I + +D E ++ + T++A++ PD ++ ATV++++ NE+ P FV +
Sbjct: 3248 GVITTQGFLDFETKQSYHLTVKAFNV---PD---EERCSFATVNIQLKGTNEYVPRFVSK 3301
Query: 149 LYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQICYYEIL--TPNTPFLID-NDGNIENTE 204
LY ++E I+ V A D D +Y I + F I+ G I +
Sbjct: 3302 LYYFEISEAAPKGTIVGEVFASDRDLGTDGE--VHYLIFGNSRKKGFQINKKTGQIYVSG 3359
Query: 205 KLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
L E V A + G R AD EV + V
Sbjct: 3360 ILDREKEERVSLKVLAKNFGSIRGADIDEVTVNV 3393
Score = 34.7 bits (78), Expect = 0.44
Identities = 36/141 (25%), Positives = 55/141 (39%), Gaps = 12/141 (8%)
Query: 86 TGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVF 145
+ G + + +D E ++ I A D G P T T++V V+DVN+ P F
Sbjct: 2311 SASGELGVTQSLDRETKERFVLMITATDSGS-PALTGT-----GTINVIVDDVNDNVPTF 2364
Query: 146 VERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID-NDGNIENT 203
+ Y + E +L V A D D S I+ N+ F I+ + G I +
Sbjct: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADASKN----AVIRIIGGNSQFTINPSTGQIITS 2420
Query: 204 EKLQYSGERLYKFTVTAYDCG 224
L + Y V D G
Sbjct: 2421 ALLDRETKDNYTLVVVCSDAG 2441
Score = 33.9 bits (76), Expect = 0.75
Identities = 40/157 (25%), Positives = 63/157 (40%), Gaps = 13/157 (8%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G + +D E Q ++ + A D G P +S A ++V + D+N+ +PVF
Sbjct: 639 GRLSTISSLDREEQAFYSLLVLATDLGSPP------QSSMARINVSLLDINDNSPVFYPV 692
Query: 149 LYRAAVTE---GKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID-NDGNIENTE 204
Y A + E G Y I V A D D + Y + F ++ G I
Sbjct: 693 QYFAHIKENEPGGSY--ITTVSATDPDLGTN-GTVKYSISAGDRSRFQVNAQSGVISTRM 749
Query: 205 KLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPT 241
L + Y+ + A D G ++ + A V I V T
Sbjct: 750 ALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDT 786
Score = 33.1 bits (74), Expect = 1.3
Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILR-VEAIDGDCSPQY 177
D N S +ATVH+ V + N P F + A + E I+R V A D D +
Sbjct: 3063 DKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAA--M 3120
Query: 178 SQICYYEILTPNTP--FLIDNDGNIENTEK-LQYSGERLYKFTVTAYDCG 224
+ + Y I + N F I++ I K L Y + ++ T++A D G
Sbjct: 3121 NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGG 3170
Score = 32.3 bits (72), Expect = 2.2
Identities = 33/150 (22%), Positives = 58/150 (38%), Gaps = 6/150 (4%)
Query: 88 EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE 147
+G I +D E T++A D + T++ V + V D+N+ P+F+
Sbjct: 1475 KGTIYTNAEIDREFANLFELTVKANDQAVPIE---TRRYALKNVTILVTDLNDNVPMFIS 1531
Query: 148 RLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT-PFLIDNDGNIENTEKL 206
+ AA + + + A D D YEI+ +T F++D
Sbjct: 1532 QNALAADPSAVIGSVLTTIMAADPDEGANGE--IEYEIINGDTDTFIVDRYSGDLRVASA 1589
Query: 207 QYSGERLYKFTVTAYDCGKKRAADDAEVEI 236
+ +Y V+A D G +R E+ I
Sbjct: 1590 LVPSQLIYNLIVSATDLGPERRKSTTELTI 1619
Score = 31.2 bits (69), Expect = 4.8
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 5/100 (5%)
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTEGK-LYDRILRVEAIDGDCSPQYSQICYYE 184
S + V V+DVN+ +PVF + Y ++E + + R +V+A D D S +I Y
Sbjct: 977 SSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKD-SGANGEIA-YT 1034
Query: 185 ILTPNT--PFLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
I NT F I DG + +L + Y V A D
Sbjct: 1035 IAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASD 1074
>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
Length = 4349
Score = 51.6 bits (122), Expect = 3e-06
Identities = 45/157 (28%), Positives = 81/157 (51%), Gaps = 14/157 (8%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G+I+ ++P+D E+ K + + A+ C + NT +V+++V DVN+ PVF
Sbjct: 2747 GVIKVRKPMDHESTKLYQIDVMAH-CLQ-----NTDVVSLVSVNIQVGDVNDNRPVFEAD 2800
Query: 149 LYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP----FLIDND-GNIEN 202
Y+A +TE + +++V AID D + + Q+ Y P + F ID++ G I
Sbjct: 2801 PYKAVLTENMPVGTSVIQVTAIDKD-TGRDGQVSYRLSADPGSNVHELFAIDSESGWITT 2859
Query: 203 TEKLQYSGERLYKFTVTAYDCGKK-RAADDAEVEIQV 238
++L + Y F V AYD G+ + + A V++ +
Sbjct: 2860 LQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSI 2896
Score = 49.3 bits (116), Expect = 2e-05
Identities = 54/223 (24%), Positives = 98/223 (43%), Gaps = 25/223 (11%)
Query: 23 NKHKPWIEAEYQGI-VMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVI 81
NK P ++ Y + V EN + L P+ +P G RL + V E ++
Sbjct: 2165 NKSNPLFQSPYYKVRVPEN---ITLYTPILHTQARSPE-------GLRLIYNIVEEEPLM 2214
Query: 82 LDKATGE-GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNE 140
L + G++ P+D E++ +H FT++A D G +ATV V V DVN+
Sbjct: 2215 LFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALG-------SFSEATVEVLVEDVND 2267
Query: 141 FAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP----FLID- 195
P F + +Y +++EG L + ++ + D ++ Y+I+ + F I+
Sbjct: 2268 NPPTFSQLVYTTSISEG-LPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQING 2326
Query: 196 NDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
+ G + ++L Y ++ + V A D G + V + V
Sbjct: 2327 STGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNV 2369
Score = 40.4 bits (93), Expect = 0.008
Identities = 43/154 (27%), Positives = 65/154 (42%), Gaps = 12/154 (7%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G++ +D E ++ +I+ C +++ S TV V + DVNE P F +
Sbjct: 3271 GILYVNASLDFETSPKYFLSIE---CSRK---SSSSLSDVTTVMVNITDVNEHRPQFPQD 3324
Query: 149 LYRAAVTEGKLY-DRILRVEAIDGDCSPQYSQICYYEILTPNT--PFLI-DNDGNIENTE 204
Y V E L D IL V A D D P S I Y ++ N F I G ++ +
Sbjct: 3325 PYSTRVLENALVGDVILTVSATDED-GPLNSDIT-YSLIGGNQLGHFTIHPKKGELQVAK 3382
Query: 205 KLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
L Y + A D G+ +D ++ IQV
Sbjct: 3383 ALDREQASSYSLKLRATDSGQPPLHEDTDIAIQV 3416
Score = 39.7 bits (91), Expect = 0.014
Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 7/107 (6%)
Query: 128 KATVHVRVN--DVNEFAPVFVERLYRAAVTEGKLY-DRILRVEAIDGDCSPQYSQICYYE 184
+ATV V +N + N+++P F + LY A + E + +++ + AID D P Y I Y
Sbjct: 2462 RATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGP-YGTIDYTI 2520
Query: 185 I-LTPNTPFLIDNDGNIENTEKL--QYSGERLYKFTVTAYDCGKKRA 228
I + F I+ +G I +KL + S ER+ V A D G + A
Sbjct: 2521 INKLASEKFSINPNGQIATLQKLDRENSTERVIAIKVMARDGGGRVA 2567
Score = 37.7 bits (86), Expect = 0.052
Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 23 NKHKPWIEA-EYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVI 81
N H P + +QG V EN + + A D D+ L GE+ F G+G+ ++
Sbjct: 1026 NLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLD--GELQYFLRAGTGLAAFSIN 1083
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
D G+I+ P+D E + T+ A D G P + T+ V++ V D N+
Sbjct: 1084 QDT----GMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTE------VYIEVTDANDN 1133
Query: 142 APVFVERLYRAAVTE-GKLYDRILRVEAIDGDCS 174
P + ++ ++ E + +L+++A D D S
Sbjct: 1134 PPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSS 1167
Score = 37.4 bits (85), Expect = 0.067
Identities = 38/152 (25%), Positives = 57/152 (37%), Gaps = 10/152 (6%)
Query: 98 DCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG 157
D E Q H ++ D ++ + V V + DVN+ P F Y + +G
Sbjct: 2029 DREQQDTHELAVEVRD------NRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDG 2082
Query: 158 -KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND-GNIENTEKLQYSGERLYK 215
+ D + +V A D D + YE T F ID G+I + Y Y
Sbjct: 2083 TEPGDVLFQVSATDEDLGT--NGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQALNKYH 2140
Query: 216 FTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQ 247
V A D G + EV + V+ P +Q
Sbjct: 2141 LKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQ 2172
Score = 37.0 bits (84), Expect = 0.088
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 9/92 (9%)
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
++ +TGE + + +D EAQ+ ++A D G+ P T V V V+D+N+
Sbjct: 2324 INGSTGE--MSTVQELDYEAQQHFHVKVRAMDKGDPPLTGET------LVVVNVSDINDN 2375
Query: 142 APVFVERLYRAAVTE-GKLYDRILRVEAIDGD 172
P F + Y A V+E +L+V+AID D
Sbjct: 2376 PPEFRQPQYEANVSELATCGHLVLKVQAIDPD 2407
Score = 36.2 bits (82), Expect = 0.15
Identities = 54/232 (23%), Positives = 85/232 (36%), Gaps = 16/232 (6%)
Query: 9 LLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICG 67
L + L S N + P + EY+G V+EN L L LD D + C
Sbjct: 2886 LSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCY 2945
Query: 68 FRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSH 127
G P + + E I +++ +D E ++ + A D K
Sbjct: 2946 IT---EGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASD---------GKFQA 2993
Query: 128 KATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-ILRVEAIDGDCSPQYSQICYYEIL 186
TV + V DVN+ +P + LY V E IL+V A D D +QI Y
Sbjct: 2994 SVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTN-AQITYSLHG 3052
Query: 187 TPNTPFLID-NDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQ 237
F +D + G + L + ++ A D G + D + ++
Sbjct: 3053 PGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQADITLHVE 3104
Score = 34.3 bits (77), Expect = 0.57
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 8/135 (5%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
GL+ P+D EA + + YD G +KS + V V D N+ AP F
Sbjct: 770 GLLTVAAPLDYEATNFYILNVTVYDLG------TPQKSSWKLLTVNVKDWNDNAPRFPPG 823
Query: 149 LYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPF-LIDNDGNIENTEKLQ 207
Y+ ++E + E D + + Y +L+P F L G + T L
Sbjct: 824 GYQLTISEDTEVGTTI-AELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLD 882
Query: 208 YSGERLYKFTVTAYD 222
E Y V A D
Sbjct: 883 RESEPRYILKVEARD 897
Score = 32.0 bits (71), Expect = 2.8
Identities = 40/164 (24%), Positives = 69/164 (42%), Gaps = 19/164 (11%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
GL+ + +D E + EH + D GE P +T + V V + DVN+ P+F +
Sbjct: 1192 GLLSTAQQLDRENKDEHILEVTVLDNGE-PSLKSTSR-----VVVGILDVNDNPPIFSHK 1245
Query: 149 LYR-------AAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIE 201
L+ + V+ G +Y R+ A D D ++ Y + F ID +
Sbjct: 1246 LFNVRLPERLSPVSPGPVY----RLVASDLD-EGLNGRVTYSIEDSDEEAFSIDLVTGVV 1300
Query: 202 NTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPS 245
++ +GE T+ A D G+ + + I+ P +PS
Sbjct: 1301 SSSSTFTAGE-YNILTIKATDSGQPPLSASVRLHIEWIPWPRPS 1343
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 48.5 bits (114), Expect = 3e-05
Identities = 47/161 (29%), Positives = 70/161 (43%), Gaps = 22/161 (13%)
Query: 72 GSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHK--- 128
G G ++ D+ T EG+I+ K+P+D E +K +TF ++A +N H+
Sbjct: 311 GDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEA---------SNLHLDHRFHS 361
Query: 129 -------ATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQI 180
ATV + V DV+E PVF + LY V E I+ V A D D +
Sbjct: 362 AGPFKDTATVKISVLDVDE-PPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRY 420
Query: 181 CYYEILTPNTPFLID-NDGNIENTEKLQYSGERLYKFTVTA 220
++ F ID N+G I E L Y F++ A
Sbjct: 421 FIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSIIA 461
Score = 36.6 bits (83), Expect = 0.12
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 8/96 (8%)
Query: 88 EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE 147
EG I E +D E+ ++ F+I A +N + K + + V DVNEF P +
Sbjct: 438 EGTIATNELLDRESTAQYNFSIIASKV------SNPLLTSKVNILINVLDVNEFPPE-IS 490
Query: 148 RLYRAAVTEGKLYDRILR-VEAIDGDCSPQYSQICY 182
Y AV E +I++ V A D D SP Q +
Sbjct: 491 VPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSF 526
Score = 35.8 bits (81), Expect = 0.20
Identities = 44/160 (27%), Positives = 69/160 (43%), Gaps = 20/160 (12%)
Query: 72 GSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK--SHKA 129
G+G F +D+ TG+ I A +D E + +T QA D T+K ++
Sbjct: 97 GAGTVFT---IDETTGD--IHAIRSLDREEKPFYTLRAQAVDI-------ETRKPLEPES 144
Query: 130 TVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQY--SQICYYEIL 186
++V D+N+ P F++ Y A V E + +L+V+A D D P Y S Y IL
Sbjct: 145 EFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDAD-DPTYGNSARVVYSIL 203
Query: 187 TPNTPFLIDNDGNIENT--EKLQYSGERLYKFTVTAYDCG 224
F ID + T + + Y+ + A D G
Sbjct: 204 QGQPYFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMG 243
>gi|47059046 dachsous 2 isoform 1 [Homo sapiens]
Length = 2916
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 9/93 (9%)
Query: 81 ILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNE 140
+LD+++G L+ P+D E + +H T+ A D G S T+ V V DVN+
Sbjct: 1213 MLDESSG--LLTTTCPLDYEMKTQHILTVLALDDG------TPALSSSQTLTVTVLDVND 1264
Query: 141 FAPVFVERLYRAAVTEGK-LYDRILRVEAIDGD 172
APVF + LY A+V E + + + RVEA+D D
Sbjct: 1265 EAPVFKQHLYEASVKENQNPGEFVTRVEALDRD 1297
Score = 47.4 bits (111), Expect = 7e-05
Identities = 47/166 (28%), Positives = 75/166 (45%), Gaps = 21/166 (12%)
Query: 81 ILDKATGEGLIRAKEP--VDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKA--TVHVRVN 136
+L + G + KEP +D E + E + A G H+A V V +
Sbjct: 1730 VLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSG-----------HRAYCKVAVLIQ 1778
Query: 137 DVNEFAPVFVERLYRAAVTEGKLYD-RILRVEAIDGDCSPQYSQICYYEILTPN--TPFL 193
D N+ +P F + +Y+A+V+E +LY+ +++V A D D + + Y IL+ N F
Sbjct: 1779 DENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSG--LNGLIEYSILSGNQEEAFQ 1836
Query: 194 IDN-DGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
ID G I L Y Y V A D G R ++ +++QV
Sbjct: 1837 IDALSGVITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQV 1882
Score = 47.4 bits (111), Expect = 7e-05
Identities = 54/186 (29%), Positives = 83/186 (44%), Gaps = 21/186 (11%)
Query: 23 NKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDA----PLRYAGEICGFRLHGSGVPF 77
N H P ++ + + IV EN + ALD DA L Y+ F HG
Sbjct: 2308 NDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVSPCFLTHGMSYDH 2367
Query: 78 EAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVND 137
+ ++D TG+ I AK+ +D E ++ T+QA D G+ + V V +
Sbjct: 2368 DLFLIDPLTGD--IHAKQILDYENGNKYCLTVQAKDKGDA--------TASLVVWVDIEG 2417
Query: 138 VNEFAPVFVERLYRAAVTEGKLYDRIL--RVEAIDGDCSPQYSQICYYEILTPNTPFLID 195
++EF P+F + Y + E K DR L RVEA D D + Y + T + F ++
Sbjct: 2418 IDEFEPIFTQDQYFFTLPE-KNKDRQLIGRVEASDADAG--IDGVILYSLGTSSPFFSVN 2474
Query: 196 -NDGNI 200
+GNI
Sbjct: 2475 KTNGNI 2480
Score = 46.6 bits (109), Expect = 1e-04
Identities = 48/161 (29%), Positives = 70/161 (43%), Gaps = 21/161 (13%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G++ +P+D E + T T+QA D A K A V V V D N+ AP F+
Sbjct: 2265 GVLYLIKPLDYEKMTKFTLTVQASD-------AEKKHFSFAVVFVSVLDDNDHAPQFMFS 2317
Query: 149 LYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTP----------NTPFLIDN- 196
+ V E + I + A+D D P Y ++ Y I++P + FLID
Sbjct: 2318 SFSCIVPENLPISSTICSINALDFDAGP-YGELT-YSIVSPCFLTHGMSYDHDLFLIDPL 2375
Query: 197 DGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQ 237
G+I + L Y Y TV A D G A+ V+I+
Sbjct: 2376 TGDIHAKQILDYENGNKYCLTVQAKDKGDATASLVVWVDIE 2416
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/220 (25%), Positives = 89/220 (40%), Gaps = 17/220 (7%)
Query: 7 PLLLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
P L ++ C+ N H P +I + Y V+EN ++ L A D DA A E
Sbjct: 1352 PSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLENQEPEVVYTVL-ASDMDAGNNRAVEY 1410
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
G E +++ +GE + +D E T I D G+ P +
Sbjct: 1411 HII----DGNTDECFTINEMSGE--LSTTRALDREQISNFTLVILCSDLGDPP------R 1458
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDCSPQYSQICYYE 184
S + VRV D N+ +P F Y+++V E ++ +L + A+D D Q Y+
Sbjct: 1459 SSVIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKD-EGLNGQTEYFL 1517
Query: 185 ILTPNTPFLID-NDGNIENTEKLQYSGERLYKFTVTAYDC 223
+ F ID G ++ + L + F+ A DC
Sbjct: 1518 TDEASGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDC 1557
Score = 42.0 bits (97), Expect = 0.003
Identities = 44/163 (26%), Positives = 64/163 (39%), Gaps = 12/163 (7%)
Query: 87 GEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFV 146
GEG + +D E + H T+ D G P A V+V V D+N+ P F
Sbjct: 787 GEGELINWVALDREHRGHHEMTVLVTDRGSPPRNATM------AVYVSVTDINDNRPFFP 840
Query: 147 ERL----YRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP-FLID-NDGNI 200
+ L V EG+ + ++ +++ Y ++ F ID N+G I
Sbjct: 841 QCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEI 900
Query: 201 ENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCK 243
T L Y Y+ +V A D G A V IQV P K
Sbjct: 901 RTTTILSYDYRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSK 943
Score = 38.1 bits (87), Expect = 0.040
Identities = 42/163 (25%), Positives = 62/163 (38%), Gaps = 28/163 (17%)
Query: 22 ANKHKPWIEA-EYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAV 80
AN H P YQ V E+ + L A+DKD G E
Sbjct: 1471 ANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKD--------------EGLNGQTEYF 1516
Query: 81 ILDKATG-------EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHV 133
+ D+A+G G ++ +D EA+ +HTF+ A DC +S + V
Sbjct: 1517 LTDEASGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDC-----SIQGSRSTTVIIKV 1571
Query: 134 RVNDVNEFAPVFVERLYRAAVT-EGKLYDRILRVEAIDGDCSP 175
V DVN+ PV + + ++ E + V A D D P
Sbjct: 1572 YVTDVNDNDPVLEQNPFDVFLSPESPTNQTTVIVRADDLDLGP 1614
Score = 36.2 bits (82), Expect = 0.15
Identities = 54/236 (22%), Positives = 89/236 (37%), Gaps = 18/236 (7%)
Query: 7 PLLLASLLASCSCNKANKHKPWIEAE-YQGIVMENDNTVLLNPPLFALDKDAPLRYAGEI 65
P L +S + + N P + Y+ V EN N + ALD+D+ + +
Sbjct: 1247 PALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQ- 1305
Query: 66 CGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKK 125
F + G FE ++ TGE + +D E Q+ T + D G
Sbjct: 1306 --FEIM-PGASFELFEINSDTGE--VVTTTILDREIQEVFTLRVLVRD------GGFPSL 1354
Query: 126 SHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEI 185
S T+ V D N+ AP F+ Y V E + + + V A D D ++ Y I
Sbjct: 1355 SSTTTILCTVEDENDHAPEFIVSSYDIEVLENQEPEVVYTVLASDMDAG--NNRAVEYHI 1412
Query: 186 LTPNTP--FLIDN-DGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQV 238
+ NT F I+ G + T L + + D G + ++++V
Sbjct: 1413 IDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRV 1468
Score = 35.0 bits (79), Expect = 0.33
Identities = 52/203 (25%), Positives = 81/203 (39%), Gaps = 17/203 (8%)
Query: 23 NKHKPWIEAE-YQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVI 81
N + P E YQ V E+ +FA D D+ L E SG EA
Sbjct: 1781 NDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSIL----SGNQEEAFQ 1836
Query: 82 LDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEF 141
+D +G +I K +D E ++ +QA D G + S+ + V+V D+N+
Sbjct: 1837 IDALSG--VITTKAILDYELTSSYSLIVQATDKGM------PRLSNTTVIKVQVTDINDN 1888
Query: 142 APVFVERLYRAAVTEGKLYDRIL-RVEAIDGDCSPQYSQICYYEILTPNTPFLID-NDGN 199
AP F+ +TE L I+ V D D + + + + P T F ID N G
Sbjct: 1889 APAFLPS-EAVEITEDSLPGVIVTHVSVHDVDLNSAFI-FSFAKESNPGTKFAIDQNTGV 1946
Query: 200 IENTEKLQYSGERLYKFTVTAYD 222
+ + L + Y+ + D
Sbjct: 1947 VVLVKTLDFEEMTEYELLIQISD 1969
Score = 33.9 bits (76), Expect = 0.75
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 14/108 (12%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
G++ + +D E E+ IQ D +GA + VRV DVN+ PVF +
Sbjct: 1945 GVVVLVKTLDFEEMTEYELLIQISDSVHYTEGA---------LVVRVLDVNDNPPVFSQD 1995
Query: 149 LYRAAVTEG-KLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLID 195
Y+ V E + +L + A D + + S Y IL+ + F ID
Sbjct: 1996 FYQVTVPESIPVGYSVLTLSATDLESNENIS----YRILSSSKEFSID 2039
Score = 32.0 bits (71), Expect = 2.8
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 7/58 (12%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFV 146
G IR ++P+D E Q T+QA G P ++T+ V++ V DVN+ P F+
Sbjct: 431 GTIRTRKPLDHETQPVVVLTVQA-QLGSAPACSSTE------VNITVMDVNDNHPAFL 481
Score = 31.2 bits (69), Expect = 4.8
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 116 EGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLY-DRILRVEAIDGDCS 174
E DG N V + + D+N +AP F + Y +++E L ++ ID D +
Sbjct: 2065 EASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWT 2124
Query: 175 PQYSQICYYEILTPNT 190
+ + + Y I++ N+
Sbjct: 2125 RENTYV-EYSIISGNS 2139
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 47.4 bits (111), Expect = 7e-05
Identities = 42/160 (26%), Positives = 68/160 (42%), Gaps = 18/160 (11%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
GLI + +D E H T+ A DG++T +ATV + V DVN+ P ++
Sbjct: 310 GLITVQRSLDREETAIHKVTVLA------SDGSSTPA--RATVTINVTDVNDNPPN-IDL 360
Query: 149 LYRAAVTEGKLY--------DRILRVEAIDGDCSPQYSQICYYEILTP-NTPFLIDNDGN 199
Y + G +Y +I + D D IC+ E P + + DN
Sbjct: 361 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 420
Query: 200 IENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVK 239
+E + L Y G + + F + A D GK A V ++++
Sbjct: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLE 460
Score = 38.9 bits (89), Expect = 0.023
Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 21/146 (14%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE- 147
G+I++ D E Q +TF ++A D G+ P +S A V + V DVN+ +PV +
Sbjct: 625 GVIKSNVSFDREQQSSYTFDVKATDGGQPP------RSSTAKVTINVMDVNDNSPVVISP 678
Query: 148 ------RLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND---G 198
+L + G + + V+ G + Y I++ N L D G
Sbjct: 679 PSNTSFKLVPLSAIPGSVVAEVFAVDVDTG-----MNAELKYTIVSGNNKGLFRIDPVTG 733
Query: 199 NIENTEKLQYSGERLYKFTVTAYDCG 224
NI EK + L++ V D G
Sbjct: 734 NITLEEKPAPTDVGLHRLVVNISDLG 759
Score = 32.0 bits (71), Expect = 2.8
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDC-SPQ 176
DG +KS A + V V+DVN+ PVF E + E + ++++ A D D S
Sbjct: 226 DGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNA 285
Query: 177 YSQICYYEILTPNTP--FLIDN-DGNIENTEKLQYSGERLYKFTVTAYD 222
+ + + P T F ++N G I L ++K TV A D
Sbjct: 286 EIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD 334
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 47.4 bits (111), Expect = 7e-05
Identities = 49/176 (27%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 9 LLASLLASCSCNKANKHKP-WIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICG 67
L + A+ + N H P + + E+Q V E V++N L DKD P A
Sbjct: 343 LTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVN--LTVEDKDDPTTGAWRAAY 400
Query: 68 FRLHGS-GVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKS 126
++G+ G FE + + T EG++ +P+D E HT I+ + + S
Sbjct: 401 TIINGNPGQSFE-IHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPS 459
Query: 127 HKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICY 182
ATVH+ V DVNE + + + + + +L V A D D S Q+ I Y
Sbjct: 460 STATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPD-SLQHQTIRY 514
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 47.4 bits (111), Expect = 7e-05
Identities = 42/160 (26%), Positives = 68/160 (42%), Gaps = 18/160 (11%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVER 148
GLI + +D E H T+ A DG++T +ATV + V DVN+ P ++
Sbjct: 310 GLITVQRSLDREETAIHKVTVLA------SDGSSTPA--RATVTINVTDVNDNPPN-IDL 360
Query: 149 LYRAAVTEGKLY--------DRILRVEAIDGDCSPQYSQICYYEILTP-NTPFLIDNDGN 199
Y + G +Y +I + D D IC+ E P + + DN
Sbjct: 361 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 420
Query: 200 IENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVK 239
+E + L Y G + + F + A D GK A V ++++
Sbjct: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLE 460
Score = 38.9 bits (89), Expect = 0.023
Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 21/146 (14%)
Query: 89 GLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVE- 147
G+I++ D E Q +TF ++A D G+ P +S A V + V DVN+ +PV +
Sbjct: 625 GVIKSNVSFDREQQSSYTFDVKATDGGQPP------RSSTAKVTINVMDVNDNSPVVISP 678
Query: 148 ------RLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDND---G 198
+L + G + + V+ G + Y I++ N L D G
Sbjct: 679 PSNTSFKLVPLSAIPGSVVAEVFAVDVDTG-----MNAELKYTIVSGNNKGLFRIDPVTG 733
Query: 199 NIENTEKLQYSGERLYKFTVTAYDCG 224
NI EK + L++ V D G
Sbjct: 734 NITLEEKPAPTDVGLHRLVVNISDLG 759
Score = 32.0 bits (71), Expect = 2.8
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTE-GKLYDRILRVEAIDGDC-SPQ 176
DG +KS A + V V+DVN+ PVF E + E + ++++ A D D S
Sbjct: 226 DGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNA 285
Query: 177 YSQICYYEILTPNTP--FLIDN-DGNIENTEKLQYSGERLYKFTVTAYD 222
+ + + P T F ++N G I L ++K TV A D
Sbjct: 286 EIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD 334
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo
sapiens]
Length = 1955
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/213 (26%), Positives = 92/213 (43%), Gaps = 27/213 (12%)
Query: 23 NKHKPWIEA-EYQGIVMEN--------DNTVLLNP-PLFALDKDAPLRYAGEICGFRLHG 72
N P+ YQG ++E+ D+ L +P + ALDKD E LH
Sbjct: 389 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE-----LHL 443
Query: 73 SGVPFEAVILDKATG-EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATV 131
+ +V TG + +PVD E Q+ +TF+I A+D ++S V
Sbjct: 444 FLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPVIV 495
Query: 132 HVRVNDVNEFAPVFVERLYRAAV-TEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT 190
+++V D N+ P F E Y V T+ + D ++++ A+D D +I Y ++
Sbjct: 496 NIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD-EGSNGEITYEILVGAQG 554
Query: 191 PFLID-NDGNIENTEKLQYSGERLYKFTVTAYD 222
F+I+ G I ++ R Y TV A D
Sbjct: 555 DFIINKTTGLITIAPGVEMIVGRTYALTVQAAD 587
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 73 SGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVH 132
+G P L + TG ++ + +D E+ + I A D PDG +T ATV+
Sbjct: 654 NGDPQRVFNLSETTG--ILTLGKALDRESTDRYILIITASD--GRPDGTST-----ATVN 704
Query: 133 VRVNDVNEFAPVFVERLYR-AAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP 191
+ V DVN+ APVF L R +V E + + +V+A D D + +Y + N
Sbjct: 705 IVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNL 762
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
F I ++G+I KL Y+ V A D
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATD 793
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 106 TFTIQAYDC-GEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-I 163
TF ++A+D G P G ATV V V D+N++ PVF +R+Y+ V + I
Sbjct: 893 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 164 LRVEAIDGDCSPQYSQICYYEILTPNTPF------LIDNDGNIENTEKLQYSGERLYKFT 217
V A D D + Y + P+ + ++ G + L ++K
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 218 VTAYDCGKKRAADDAEVEIQV 238
V A+D G+ + A V+I V
Sbjct: 1006 VVAFDDGEPVMSSSATVKILV 1026
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 12/129 (9%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQY 177
DGA + T+ ++V D+++ +PVF Y V E IL++EA D D
Sbjct: 793 DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANV 852
Query: 178 SQICYYEILTPNTPF---LIDNDGNIENTEKLQYSG----ERLYKFTVTAYDCGKKRAAD 230
S Y I +P L G + L Y E F V A+D
Sbjct: 853 S----YRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPG 908
Query: 231 DAEVEIQVK 239
A V + VK
Sbjct: 909 IATVTVIVK 917
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo
sapiens]
Length = 1932
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/213 (26%), Positives = 92/213 (43%), Gaps = 27/213 (12%)
Query: 23 NKHKPWIEA-EYQGIVMEN--------DNTVLLNP-PLFALDKDAPLRYAGEICGFRLHG 72
N P+ YQG ++E+ D+ L +P + ALDKD E LH
Sbjct: 367 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE-----LHL 421
Query: 73 SGVPFEAVILDKATG-EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATV 131
+ +V TG + +PVD E Q+ +TF+I A+D ++S V
Sbjct: 422 FLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPVIV 473
Query: 132 HVRVNDVNEFAPVFVERLYRAAV-TEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT 190
+++V D N+ P F E Y V T+ + D ++++ A+D D +I Y ++
Sbjct: 474 NIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD-EGSNGEITYEILVGAQG 532
Query: 191 PFLID-NDGNIENTEKLQYSGERLYKFTVTAYD 222
F+I+ G I ++ R Y TV A D
Sbjct: 533 DFIINKTTGLITIAPGVEMIVGRTYALTVQAAD 565
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 73 SGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVH 132
+G P L + TG ++ + +D E+ + I A D PDG +T ATV+
Sbjct: 632 NGDPQRVFNLSETTG--ILTLGKALDRESTDRYILIITASD--GRPDGTST-----ATVN 682
Query: 133 VRVNDVNEFAPVFVERLYR-AAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP 191
+ V DVN+ APVF L R +V E + + +V+A D D + +Y + N
Sbjct: 683 IVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNL 740
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
F I ++G+I KL Y+ V A D
Sbjct: 741 FRITSNGSIYTAVKLNREVRDYYELVVVATD 771
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 106 TFTIQAYDC-GEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-I 163
TF ++A+D G P G ATV V V D+N++ PVF +R+Y+ V + I
Sbjct: 871 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 923
Query: 164 LRVEAIDGDCSPQYSQICYYEILTPNTPF------LIDNDGNIENTEKLQYSGERLYKFT 217
V A D D + Y + P+ + ++ G + L ++K
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 218 VTAYDCGKKRAADDAEVEIQV 238
V A+D G+ + A V+I V
Sbjct: 984 VVAFDDGEPVMSSSATVKILV 1004
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 12/129 (9%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQY 177
DGA + T+ ++V D+++ +PVF Y V E IL++EA D D
Sbjct: 771 DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANV 830
Query: 178 SQICYYEILTPNTPF---LIDNDGNIENTEKLQYSG----ERLYKFTVTAYDCGKKRAAD 230
S Y I +P L G + L Y E F V A+D
Sbjct: 831 S----YRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPG 886
Query: 231 DAEVEIQVK 239
A V + VK
Sbjct: 887 IATVTVIVK 895
>gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo
sapiens]
Length = 1677
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/213 (26%), Positives = 92/213 (43%), Gaps = 27/213 (12%)
Query: 23 NKHKPWIEA-EYQGIVMEN--------DNTVLLNP-PLFALDKDAPLRYAGEICGFRLHG 72
N P+ YQG ++E+ D+ L +P + ALDKD E LH
Sbjct: 389 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE-----LHL 443
Query: 73 SGVPFEAVILDKATG-EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATV 131
+ +V TG + +PVD E Q+ +TF+I A+D ++S V
Sbjct: 444 FLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPVIV 495
Query: 132 HVRVNDVNEFAPVFVERLYRAAV-TEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT 190
+++V D N+ P F E Y V T+ + D ++++ A+D D +I Y ++
Sbjct: 496 NIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD-EGSNGEITYEILVGAQG 554
Query: 191 PFLID-NDGNIENTEKLQYSGERLYKFTVTAYD 222
F+I+ G I ++ R Y TV A D
Sbjct: 555 DFIINKTTGLITIAPGVEMIVGRTYALTVQAAD 587
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 73 SGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVH 132
+G P L + TG ++ + +D E+ + I A D PDG +T ATV+
Sbjct: 654 NGDPQRVFNLSETTG--ILTLGKALDRESTDRYILIITASD--GRPDGTST-----ATVN 704
Query: 133 VRVNDVNEFAPVFVERLYR-AAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP 191
+ V DVN+ APVF L R +V E + + +V+A D D + +Y + N
Sbjct: 705 IVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNL 762
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
F I ++G+I KL Y+ V A D
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATD 793
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 106 TFTIQAYDC-GEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-I 163
TF ++A+D G P G ATV V V D+N++ PVF +R+Y+ V + I
Sbjct: 893 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 164 LRVEAIDGDCSPQYSQICYYEILTPNTPF------LIDNDGNIENTEKLQYSGERLYKFT 217
V A D D + Y + P+ + ++ G + L ++K
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 218 VTAYDCGKKRAADDAEVEIQV 238
V A+D G+ + A V+I V
Sbjct: 1006 VVAFDDGEPVMSSSATVKILV 1026
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 12/129 (9%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQY 177
DGA + T+ ++V D+++ +PVF Y V E IL++EA D D
Sbjct: 793 DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANV 852
Query: 178 SQICYYEILTPNTPF---LIDNDGNIENTEKLQYSG----ERLYKFTVTAYDCGKKRAAD 230
S Y I +P L G + L Y E F V A+D
Sbjct: 853 S----YRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPG 908
Query: 231 DAEVEIQVK 239
A V + VK
Sbjct: 909 IATVTVIVK 917
>gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo
sapiens]
Length = 1682
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/213 (26%), Positives = 92/213 (43%), Gaps = 27/213 (12%)
Query: 23 NKHKPWIEA-EYQGIVMEN--------DNTVLLNP-PLFALDKDAPLRYAGEICGFRLHG 72
N P+ YQG ++E+ D+ L +P + ALDKD E LH
Sbjct: 394 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE-----LHL 448
Query: 73 SGVPFEAVILDKATG-EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATV 131
+ +V TG + +PVD E Q+ +TF+I A+D ++S V
Sbjct: 449 FLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPVIV 500
Query: 132 HVRVNDVNEFAPVFVERLYRAAV-TEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT 190
+++V D N+ P F E Y V T+ + D ++++ A+D D +I Y ++
Sbjct: 501 NIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD-EGSNGEITYEILVGAQG 559
Query: 191 PFLID-NDGNIENTEKLQYSGERLYKFTVTAYD 222
F+I+ G I ++ R Y TV A D
Sbjct: 560 DFIINKTTGLITIAPGVEMIVGRTYALTVQAAD 592
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 73 SGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVH 132
+G P L + TG ++ + +D E+ + I A D PDG +T ATV+
Sbjct: 659 NGDPQRVFNLSETTG--ILTLGKALDRESTDRYILIITASD--GRPDGTST-----ATVN 709
Query: 133 VRVNDVNEFAPVFVERLYR-AAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP 191
+ V DVN+ APVF L R +V E + + +V+A D D + +Y + N
Sbjct: 710 IVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNL 767
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
F I ++G+I KL Y+ V A D
Sbjct: 768 FRITSNGSIYTAVKLNREVRDYYELVVVATD 798
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 106 TFTIQAYDC-GEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-I 163
TF ++A+D G P G ATV V V D+N++ PVF +R+Y+ V + I
Sbjct: 898 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 950
Query: 164 LRVEAIDGDCSPQYSQICYYEILTPNTPF------LIDNDGNIENTEKLQYSGERLYKFT 217
V A D D + Y + P+ + ++ G + L ++K
Sbjct: 951 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1010
Query: 218 VTAYDCGKKRAADDAEVEIQV 238
V A+D G+ + A V+I V
Sbjct: 1011 VVAFDDGEPVMSSSATVKILV 1031
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 12/129 (9%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQY 177
DGA + T+ ++V D+++ +PVF Y V E IL++EA D D
Sbjct: 798 DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANV 857
Query: 178 SQICYYEILTPNTPF---LIDNDGNIENTEKLQYSG----ERLYKFTVTAYDCGKKRAAD 230
S Y I +P L G + L Y E F V A+D
Sbjct: 858 S----YRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPG 913
Query: 231 DAEVEIQVK 239
A V + VK
Sbjct: 914 IATVTVIVK 922
>gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo
sapiens]
Length = 1539
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/213 (26%), Positives = 92/213 (43%), Gaps = 27/213 (12%)
Query: 23 NKHKPWIEA-EYQGIVMEN--------DNTVLLNP-PLFALDKDAPLRYAGEICGFRLHG 72
N P+ YQG ++E+ D+ L +P + ALDKD E LH
Sbjct: 389 NNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE-----LHL 443
Query: 73 SGVPFEAVILDKATG-EGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATV 131
+ +V TG + +PVD E Q+ +TF+I A+D ++S V
Sbjct: 444 FLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--------GVQESEPVIV 495
Query: 132 HVRVNDVNEFAPVFVERLYRAAV-TEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNT 190
+++V D N+ P F E Y V T+ + D ++++ A+D D +I Y ++
Sbjct: 496 NIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD-EGSNGEITYEILVGAQG 554
Query: 191 PFLID-NDGNIENTEKLQYSGERLYKFTVTAYD 222
F+I+ G I ++ R Y TV A D
Sbjct: 555 DFIINKTTGLITIAPGVEMIVGRTYALTVQAAD 587
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 73 SGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVH 132
+G P L + TG ++ + +D E+ + I A D PDG +T ATV+
Sbjct: 654 NGDPQRVFNLSETTG--ILTLGKALDRESTDRYILIITASD--GRPDGTST-----ATVN 704
Query: 133 VRVNDVNEFAPVFVERLYR-AAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTP 191
+ V DVN+ APVF L R +V E + + +V+A D D + +Y + N
Sbjct: 705 IVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAG--INGQVHYSLGNFNNL 762
Query: 192 FLIDNDGNIENTEKLQYSGERLYKFTVTAYD 222
F I ++G+I KL Y+ V A D
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATD 793
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 106 TFTIQAYDC-GEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDR-I 163
TF ++A+D G P G ATV V V D+N++ PVF +R+Y+ V + I
Sbjct: 893 TFLVEAFDIYGTMPPGI-------ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 164 LRVEAIDGDCSPQYSQICYYEILTPNTPF------LIDNDGNIENTEKLQYSGERLYKFT 217
V A D D + Y + P+ + ++ G + L ++K
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 218 VTAYDCGKKRAADDAEVEIQV 238
V A+D G+ + A V+I V
Sbjct: 1006 VVAFDDGEPVMSSSATVKILV 1026
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 12/129 (9%)
Query: 119 DGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEG-KLYDRILRVEAIDGDCSPQY 177
DGA + T+ ++V D+++ +PVF Y V E IL++EA D D
Sbjct: 793 DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANV 852
Query: 178 SQICYYEILTPNTPF---LIDNDGNIENTEKLQYSG----ERLYKFTVTAYDCGKKRAAD 230
S Y I +P L G + L Y E F V A+D
Sbjct: 853 S----YRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPG 908
Query: 231 DAEVEIQVK 239
A V + VK
Sbjct: 909 IATVTVIVK 917
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,882,483
Number of Sequences: 37866
Number of extensions: 1965228
Number of successful extensions: 6177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 5435
Number of HSP's gapped (non-prelim): 736
length of query: 956
length of database: 18,247,518
effective HSP length: 112
effective length of query: 844
effective length of database: 14,006,526
effective search space: 11821507944
effective search space used: 11821507944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.