Search of human proteins with 41872339

Search of human proteins with 41872339

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41872339 periphilin 1 isoform 5 [Homo sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41872339 periphilin 1 isoform 5 [Homo sapiens]                     521   e-148
gi|41872349 periphilin 1 isoform 4 [Homo sapiens]                     518   e-147
gi|219842244 periphilin 1 isoform 6 [Homo sapiens]                    504   e-143
gi|41872368 periphilin 1 isoform 2 [Homo sapiens]                     466   e-132
gi|48255929 periphilin 1 isoform 1 [Homo sapiens]                     455   e-128
gi|41872344 periphilin 1 isoform 3 [Homo sapiens]                     455   e-128
gi|219842250 periphilin 1 isoform 8 [Homo sapiens]                    451   e-127
gi|219842247 periphilin 1 isoform 7 [Homo sapiens]                    403   e-113
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          51   9e-07
gi|50083281 KIAA1853 protein [Homo sapiens]                            48   7e-06
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     48   1e-05
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    48   1e-05
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]    45   5e-05
gi|62526045 zinc finger protein 638 [Homo sapiens]                     44   1e-04
gi|21626468 zinc finger protein 638 [Homo sapiens]                     44   1e-04
gi|52426743 cisplatin resistance-associated overexpressed protei...    43   2e-04
gi|19923485 cisplatin resistance-associated overexpressed protei...    43   2e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     42   4e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         42   4e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    42   5e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    42   5e-04
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    42   5e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   5e-04
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     41   0.001
gi|221139764 PHD and ring finger domains 1 [Homo sapiens]              41   0.001
gi|197313748 SET domain containing 2 [Homo sapiens]                    41   0.001
gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c...    41   0.001
gi|50962882 G patch domain containing 8 [Homo sapiens]                 40   0.002
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    40   0.003
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 39   0.004

>gi|41872339 periphilin 1 isoform 5 [Homo sapiens]
          Length = 258

 Score =  521 bits (1343), Expect = e-148
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRR 60
           MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRR
Sbjct: 1   MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRR 60

Query: 61  KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ 120
           KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ
Sbjct: 61  KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ 120

Query: 121 HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 180
           HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE
Sbjct: 121 HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 180

Query: 181 LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLT 240
           LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLT
Sbjct: 181 LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLT 240

Query: 241 TRSKAIASKTKEIEQVRV 258
           TRSKAIASKTKEIEQVRV
Sbjct: 241 TRSKAIASKTKEIEQVRV 258


>gi|41872349 periphilin 1 isoform 4 [Homo sapiens]
          Length = 319

 Score =  518 bits (1334), Expect = e-147
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 1   MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRR 60
           MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRR
Sbjct: 1   MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRR 60

Query: 61  KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ 120
           KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ
Sbjct: 61  KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQ 120

Query: 121 HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 180
           HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE
Sbjct: 121 HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 180

Query: 181 LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLT 240
           LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLT
Sbjct: 181 LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLT 240

Query: 241 TRSKAIASKTKEIEQV 256
           TRSKAIASKTKEIEQV
Sbjct: 241 TRSKAIASKTKEIEQV 256


>gi|219842244 periphilin 1 isoform 6 [Homo sapiens]
          Length = 434

 Score =  504 bits (1297), Expect = e-143
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 8   MWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH 67
           MWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH 60

Query: 68  YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP 127
           YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP
Sbjct: 61  YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP 120

Query: 128 GASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 187
           GASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK
Sbjct: 121 GASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 180

Query: 188 WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 247
           WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA
Sbjct: 181 WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 240

Query: 248 SKTKEIEQV 256
           SKTKEIEQV
Sbjct: 241 SKTKEIEQV 249


>gi|41872368 periphilin 1 isoform 2 [Homo sapiens]
          Length = 374

 Score =  466 bits (1200), Expect = e-132
 Identities = 248/313 (79%), Positives = 248/313 (79%), Gaps = 59/313 (18%)

Query: 1   MAYRRDEMWSEGRYEY-----ERIP----------------------------------- 20
           MAYRRDEMWSEGRYEY     ER P                                   
Sbjct: 1   MAYRRDEMWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYY 60

Query: 21  -----------------RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSF 63
                            R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSF
Sbjct: 61  SHVDYRDYDEGRSFSHDRRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSF 118

Query: 64  YSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRK 123
           YSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRK
Sbjct: 119 YSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRK 178

Query: 124 SVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAE 183
           SVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAE
Sbjct: 179 SVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAE 238

Query: 184 AASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRS 243
           AASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRS
Sbjct: 239 AASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRS 298

Query: 244 KAIASKTKEIEQV 256
           KAIASKTKEIEQV
Sbjct: 299 KAIASKTKEIEQV 311


>gi|48255929 periphilin 1 isoform 1 [Homo sapiens]
          Length = 458

 Score =  455 bits (1171), Expect = e-128
 Identities = 229/236 (97%), Positives = 229/236 (97%), Gaps = 2/236 (0%)

Query: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128

Query: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE
Sbjct: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 188

Query: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200
           RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 189 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 248

Query: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 256
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV
Sbjct: 249 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 304


>gi|41872344 periphilin 1 isoform 3 [Homo sapiens]
          Length = 367

 Score =  455 bits (1171), Expect = e-128
 Identities = 229/236 (97%), Positives = 229/236 (97%), Gaps = 2/236 (0%)

Query: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128

Query: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE
Sbjct: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 188

Query: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200
           RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 189 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 248

Query: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 256
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV
Sbjct: 249 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 304


>gi|219842250 periphilin 1 isoform 8 [Homo sapiens]
          Length = 293

 Score =  451 bits (1161), Expect = e-127
 Identities = 229/249 (91%), Positives = 230/249 (92%), Gaps = 19/249 (7%)

Query: 8   MWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH 67
           MWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSH 60

Query: 68  YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP 127
           YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH      
Sbjct: 61  YARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH------ 114

Query: 128 GASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 187
                        R+KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK
Sbjct: 115 -------------RNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 161

Query: 188 WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 247
           WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA
Sbjct: 162 WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIA 221

Query: 248 SKTKEIEQV 256
           SKTKEIEQV
Sbjct: 222 SKTKEIEQV 230


>gi|219842247 periphilin 1 isoform 7 [Homo sapiens]
          Length = 348

 Score =  403 bits (1035), Expect = e-113
 Identities = 209/236 (88%), Positives = 210/236 (88%), Gaps = 21/236 (8%)

Query: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128

Query: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR                  
Sbjct: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR------------------ 170

Query: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200
            +KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 171 -NKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 229

Query: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 256
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV
Sbjct: 230 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 285


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 73/293 (24%), Positives = 113/293 (38%), Gaps = 55/293 (18%)

Query: 5   RDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFY 64
           RD   S   Y+     R R+P ++     S   +   D S SR P     RD  R +S  
Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN--KARDHSRSRSPN 468

Query: 65  SSH-YARERSPYK-RDNTFF---------------------RESPVGRKDSPHSRSGSSV 101
            +   +R RSP K RD++                       R+S    K+  H RS S  
Sbjct: 469 KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS 528

Query: 102 ------SSRSYSPERSKSYS---FHQSQHRKSVRPGASYKRQNEGNPERDKER-----PV 147
                  SRS + ER +S S     + +HR+S  P     R+   +P +++ER       
Sbjct: 529 KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS 588

Query: 148 QSLKTSRDTSPSSGSAVSSSKVLDKP-----SRLTEKELAEAASKWAAEKLEKSDESNLP 202
           +    SR  SP+  S  S  +   K      SR   KE   + S+ ++++ + S +S +P
Sbjct: 589 EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPS-QSTVP 647

Query: 203 EISEYEAGSTAPLFTDQPEEPESNTTHGIELF---------EDSQL-TTRSKA 245
              +++   T      Q   P   ++H    F         +DSQ   T SKA
Sbjct: 648 RSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 53/202 (26%), Positives = 78/202 (38%), Gaps = 29/202 (14%)

Query: 17  ERIPRERAPPRSHPS-DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPY 75
           ER  R  + PR      +SG    + DHS SR P     R             +R RSPY
Sbjct: 374 ERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR-------------SRSRSPY 420

Query: 76  KRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQN 135
           K  +     SP   +D   SRS      RS S   +K+       H +S  P  +  R  
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA-----RDHSRSRSPNKARDRSR 475

Query: 136 EGNPERDKER-----PVQSLKTSRDTSPSS----GSAVSSSKVLD-KPSRLTEKELAEAA 185
             +P ++++      P +     R  SPS       + SSSK  D + SR   KE     
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535

Query: 186 SKWAAEKLEKSDESNLPEISEY 207
           S+   ++ ++S   +  E  E+
Sbjct: 536 SRSPNKERDRSQSRSPSEEREH 557



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 51/215 (23%), Positives = 83/215 (38%), Gaps = 34/215 (15%)

Query: 2   AYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRK 61
           A  R    S  +    R  R  +  R+H    S + W R+ HS +R    + +     R 
Sbjct: 272 ASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRS-HSWKRN-HSRARSRTRKGILSQMGRH 329

Query: 62  SFYSSHYA-----RERSPYKRDNTFFRESPVGRKDSPHSRSGS--------------SVS 102
           S   SH       + R+P +  +  +  +P   +   HSRS S              S  
Sbjct: 330 SQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR 389

Query: 103 SRSYSPERSKSYSFHQSQH--RKSVRPGASYK-----RQNEGNPERDKER---PVQSLKT 152
           S+S SP + + +S  +S +  R   R  + YK     R    N  RD  R   P ++   
Sbjct: 390 SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDR 449

Query: 153 SRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 187
           SR  SP+     S S+    P++  ++  + + SK
Sbjct: 450 SRSRSPNKARDHSRSR---SPNKARDRSRSRSPSK 481



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 43/172 (25%), Positives = 65/172 (37%), Gaps = 7/172 (4%)

Query: 46  SRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRS 105
           SR+  Y       R KS Y+    R R      +   R S  G +   HSR  S    R+
Sbjct: 252 SREKSYSPTEMSSRVKS-YNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRN 310

Query: 106 YSPERSKSYSFHQSQ---HRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGS 162
           +S  RS++     SQ   H +S R  +  K QN+    R       S   S++ S S   
Sbjct: 311 HSRARSRTRKGILSQMGRHSQS-RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR 369

Query: 163 AVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 214
             SSSK  D     + ++ +  +   +  K      S  P  +   + S +P
Sbjct: 370 --SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 55/195 (28%), Positives = 78/195 (40%), Gaps = 33/195 (16%)

Query: 3   YRRDEMWSEGRYEYERIPR------ERAPPRSHPSDESGYRWTRDDHSASRQPEY----- 51
           Y +    S  +  Y R P       +R+PP           ++R   S  R P+Y     
Sbjct: 416 YTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDS 475

Query: 52  --RDMRDGFRRKSFYSSHYARER------------SPYKRDNTFFRESP-----VGRKDS 92
             R+     RR+  YS    R R            S  KR   ++R SP     +    S
Sbjct: 476 QQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSS 535

Query: 93  PHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKT 152
            +S S S  +SRSYS  RS+S S  +S+ R S    +S +  + G+  R + R  +S   
Sbjct: 536 WYSSSSSRSASRSYSRSRSRSRSRRRSRTRTS--SSSSSRSPSPGSRSRSRSRS-RSRSR 592

Query: 153 SRDTSPSSGSAVSSS 167
           SR  S S  SA S S
Sbjct: 593 SRSQSRSYSSADSYS 607



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 49/160 (30%), Positives = 65/160 (40%), Gaps = 23/160 (14%)

Query: 23  RAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFF 82
           R+ P    S  S Y  TR    +SR P  R      + +S  S   +  RSP     +  
Sbjct: 382 RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGK 441

Query: 83  RESPVGRKDSPHSRSGSSVSSRSYSP--ERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140
           R  P     S  SRS  S S   YSP  ER   YS   SQ R+  R   + +R+   +P 
Sbjct: 442 RSPP-----SRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER---ARRRRRSYSPM 493

Query: 141 RDKERPVQS-LKTSRDT------------SPSSGSAVSSS 167
           R + R   S L+  R T            SPSS  ++SS+
Sbjct: 494 RKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSST 533



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 37/110 (33%), Positives = 43/110 (39%), Gaps = 18/110 (16%)

Query: 19  IPRERAPPRSHPSDESGYRW--TRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYK 76
           IP  R  P S  S  S   W  +    SASR                YS   +R RS  +
Sbjct: 517 IPYYRPSPSSSGSLSSTSSWYSSSSSRSASRS---------------YSRSRSRSRSR-R 560

Query: 77  RDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVR 126
           R  T    S   R  SP SRS S   SRS S  RS+S S+  +    S R
Sbjct: 561 RSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610



 Score = 32.3 bits (72), Expect = 0.42
 Identities = 49/213 (23%), Positives = 76/213 (35%), Gaps = 29/213 (13%)

Query: 14  YEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERS 73
           +E ++  RE    R H +       T    S  ++ + +  R   RR S YS       S
Sbjct: 77  WERDKTCRELGATRGHSASHDK-DLTPPPSSRGKKKKKKSTRKKRRRSSSYSP------S 129

Query: 74  PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVR--PGASY 131
           P K+           +    H R  S    R +S    KS    + +H+K  R  P  S+
Sbjct: 130 PVKKKKK--------KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSH 181

Query: 132 KRQNEGNPER---DKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKW 188
           + ++   P R    + RP       R  SP  G      K   + SR   K L + + + 
Sbjct: 182 RHRHHRCPSRSQSSESRPSSCESRHRGRSPEEG-----QKSRRRHSRRCSKTLCKDSPEA 236

Query: 189 AAEKLEKSDESNLPEISE----YEAGSTAPLFT 217
            + +        L  +S       +GS A LFT
Sbjct: 237 QSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 50/192 (26%), Positives = 75/192 (39%), Gaps = 8/192 (4%)

Query: 19  IPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRD 78
           +P     P   PS +S      ++    ++   +  R   R   ++SS  +R RS  K  
Sbjct: 730 LPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAK 789

Query: 79  NTFFRESPVGRKDSPHSRSGS-SVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEG 137
           ++     P   +    SRS S S   R++SPER +      + +R S  PGAS KR    
Sbjct: 790 HSL----PSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSR 845

Query: 138 NPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSD 197
           +P   K++       SR  S +   +VS SK             A +AS    E    S 
Sbjct: 846 SPHEKKKK---RRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQ 902

Query: 198 ESNLPEISEYEA 209
           E +     E EA
Sbjct: 903 ERSRGVSQEKEA 914



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 10/181 (5%)

Query: 13  RYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKS-FYSSHYARE 71
           +Y      R R+  ++  S  S YR  R   S SR P  R      RR+     + Y   
Sbjct: 773 KYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVS 832

Query: 72  RSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASY 131
           RSP          SP  +K    SRS +   +RS S   SK         + + RP A  
Sbjct: 833 RSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSK---------QAAPRPAAPA 883

Query: 132 KRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAE 191
                       E    S + SR  S    + +SS+ V    S++T+  +A+  +  AA 
Sbjct: 884 AHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAAS 943

Query: 192 K 192
           K
Sbjct: 944 K 944


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 60/213 (28%), Positives = 79/213 (37%), Gaps = 29/213 (13%)

Query: 2   AYRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRK 61
           A  R   WS  R    R  R R+  R H    S     RD H  SR P  R    G RR+
Sbjct: 415 ARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS-----RDGHRYSRSPARRGGY-GPRRR 468

Query: 62  SFYSSHYARERSPYKRDNTFFRESPVGRKDSPHS----RSGSSVSSRSYSPERSKSYSFH 117
           S   SH       Y+R     R     R  S  S    RS S   SRS+SP  S+S S  
Sbjct: 469 SRSRSHSGDR---YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRS 525

Query: 118 QSQ---------HRKSVRPGAS---YKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVS 165
           +S+           K  RP AS    ++  +  P   KE      K     +P     + 
Sbjct: 526 RSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPK----LTPQEKLKLR 581

Query: 166 SSKVLDKPSRLTEKELAEAASKWAAEKLEKSDE 198
             K L++  +  +K   E   +   E+ E+ DE
Sbjct: 582 MQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 62/221 (28%), Positives = 84/221 (38%), Gaps = 24/221 (10%)

Query: 4   RRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDD-HSASRQPEYRDMRDGFRRKS 62
           RR    S       R    R+  RS      G  + R   H+ SR   +   R   RR S
Sbjct: 374 RRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433

Query: 63  FYSSHYARERSPYKRDNTFFRESPVGRKD-SPHSRSGSSVSSRSYSPERSKSYSFHQSQH 121
              S   R      RD   +  SP  R    P  RS     SRS+S +R +       +H
Sbjct: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRS----RSRSHSGDRYRR-GGRGLRH 488

Query: 122 RKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDK---PSRLTE 178
             S R  +S+      +P R +     SL  SR  SPS   + S S+   +   PS   E
Sbjct: 489 HSSSRSRSSWSL----SPSRSR-----SLTRSRSHSPSPSQSRSRSRSRSQSPSPSPARE 539

Query: 179 KELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 219
           K    AAS    EKL+K++ +     +  E G+  P  T Q
Sbjct: 540 KLTRPAASPAVGEKLKKTEPA-----AGKETGAAKPKLTPQ 575


>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
          Length = 282

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 47/154 (30%), Positives = 59/154 (38%), Gaps = 27/154 (17%)

Query: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80
           R R+P R H S   G   +R   S SR    R  R  + R  +  S Y+R  SPY R   
Sbjct: 124 RSRSPRRRHRSRSRGPSCSRS-RSRSRYRGSRYSRSPYSRSPYSRSRYSR--SPYSRSR- 179

Query: 81  FFRESPVG-----------------RKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRK 123
            +RES  G                      HS+SGSS SSRS S  +S S     ++  K
Sbjct: 180 -YRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSS-----ARRSK 233

Query: 124 SVRPGASYKRQNEGNPERDKERPVQSLKTSRDTS 157
           S     S  R    +  R   R  +    SR  S
Sbjct: 234 SSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRS 267



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 44/146 (30%), Positives = 59/146 (40%), Gaps = 15/146 (10%)

Query: 10  SEGRYE---YERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSS 66
           S  RY    Y R P  R+P        S  R++R  +S SR  E R     +    + +S
Sbjct: 146 SRSRYRGSRYSRSPYSRSP-------YSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNS 198

Query: 67  HYAR---ERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRK 123
            Y+R    RS  K  ++    S    K S   RS SS  SRS S  RS S +  +S  R 
Sbjct: 199 RYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMT--RSPPRV 256

Query: 124 SVRPGASYKRQNEGNPERDKERPVQS 149
           S R   S  R        ++E  + S
Sbjct: 257 SKRKSKSRSRSKRPPKSPEEEGQMSS 282



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 19/180 (10%)

Query: 37  RWTRDDHSASRQ--PEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPH 94
           R+ R D   SRQ  P  R    G+ R+S   S+  R RSP +R                 
Sbjct: 91  RYGRRDLPRSRQGEPRGRSRGGGYGRRS--RSYGRRSRSPRRRHR--------------- 133

Query: 95  SRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSR 154
           SRS     SRS S  R +   + +S + +S    + Y R         + R   S  +S 
Sbjct: 134 SRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSS 193

Query: 155 DTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 214
             S S  S   SS+   K    T    A  +   +A + + S  S     S   + + +P
Sbjct: 194 GYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP 253


>gi|62526045 zinc finger protein 638 [Homo sapiens]
          Length = 1978

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 63/233 (27%), Positives = 86/233 (36%), Gaps = 40/233 (17%)

Query: 10  SEGRYEYERIPRERA----PPRSHPSDESG-YRWTRDDHSASRQPEYRDMRDGFRRKSFY 64
           +EG  +    PR R+    P RS  S  S  +R +R       +P  R  R   R  S Y
Sbjct: 474 NEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRY 533

Query: 65  SSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 124
            S  +R RSPY+  N F                GS    RS SPER    S   S  +K+
Sbjct: 534 RSR-SRSRSPYRIRNPF---------------RGSPKCFRSVSPERMSRRSVRSSDRKKA 577

Query: 125 VRP-------GASYKRQNEGNPERDKERPVQSLKTSRDTSPS--------SGSAVSSSKV 169
           +         G  + +Q           P Q  KTS  T PS        S S +    +
Sbjct: 578 LEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSI 637

Query: 170 LDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEE 222
             K   L +  L+E   K  ++K   S +  L +      GS   L T+ PE+
Sbjct: 638 RCKSKNLEDDTLSEC--KQVSDK-AVSLQRKLRKEQSLHYGSVL-LITELPED 686


>gi|21626468 zinc finger protein 638 [Homo sapiens]
          Length = 1978

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 63/233 (27%), Positives = 86/233 (36%), Gaps = 40/233 (17%)

Query: 10  SEGRYEYERIPRERA----PPRSHPSDESG-YRWTRDDHSASRQPEYRDMRDGFRRKSFY 64
           +EG  +    PR R+    P RS  S  S  +R +R       +P  R  R   R  S Y
Sbjct: 474 NEGNRKENETPRRRSHSPSPRRSRRSSSSHRFRRSRSPMHYMYRPRSRSPRICHRFISRY 533

Query: 65  SSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 124
            S  +R RSPY+  N F                GS    RS SPER    S   S  +K+
Sbjct: 534 RSR-SRSRSPYRIRNPF---------------RGSPKCFRSVSPERMSRRSVRSSDRKKA 577

Query: 125 VRP-------GASYKRQNEGNPERDKERPVQSLKTSRDTSPS--------SGSAVSSSKV 169
           +         G  + +Q           P Q  KTS  T PS        S S +    +
Sbjct: 578 LEDVVQRSGHGTEFNKQKHLEAADKGHSPAQKPKTSSGTKPSVKPTSATKSDSNLGGHSI 637

Query: 170 LDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEE 222
             K   L +  L+E   K  ++K   S +  L +      GS   L T+ PE+
Sbjct: 638 RCKSKNLEDDTLSEC--KQVSDK-AVSLQRKLRKEQSLHYGSVL-LITELPED 686


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 46/183 (25%), Positives = 75/183 (40%), Gaps = 12/183 (6%)

Query: 5   RDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFY 64
           RDE   + + E E   +ER   R    +    R   ++     +   R+ R   R +S +
Sbjct: 243 RDERLKKEKQEREEREKERERERE---ERERKRRREEEEREKERARDRERRKRSRSRSRH 299

Query: 65  SSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 124
           SS  +  R    RD+   R      ++   SRS     SRS+     K  S  + + R  
Sbjct: 300 SSRTSDRRCSRSRDHKRSRS-----RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSK 354

Query: 125 VRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEA 184
            R   SYK +++    RD+E+  +S +  +  S    S+V S    +K S  T  E  E+
Sbjct: 355 SRDRKSYKHRSK---SRDREQDRKSKEKEKRGSDDKKSSVKSGS-REKQSEDTNTESKES 410

Query: 185 ASK 187
            +K
Sbjct: 411 DTK 413



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 46/165 (27%), Positives = 63/165 (38%), Gaps = 7/165 (4%)

Query: 4   RRDEMWSEGRYEYERIPRERAPPRS-HPSDESGYRWTRD-DHSASRQPEYRDMRDGFRRK 61
           RR+E   E     +R  R+R+  RS H S  S  R +R  DH  SR  E R  R   RR+
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332

Query: 62  SFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH 121
           S   SH   ER    R     R     RK   H            S E+ K  S      
Sbjct: 333 S--RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS---DDK 387

Query: 122 RKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSS 166
           + SV+ G+  K+  + N E  +      +  + +   S G   S+
Sbjct: 388 KSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 35/168 (20%), Positives = 64/168 (38%), Gaps = 5/168 (2%)

Query: 42  DHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSV 101
           D    ++ + R+ R+  R +        R R   +R+    R+    ++    SR  S  
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303

Query: 102 SSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSG 161
           S R  S  RS+ +   +S+ R+  R     + ++    ER      +  + S+     S 
Sbjct: 304 SDRRCS--RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361

Query: 162 SAVSSSKVLDKPSRLTEKELAEAASKWAAEK---LEKSDESNLPEISE 206
              S S+  ++  +  EKE   +  K ++ K    EK  E    E  E
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKE 409


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 46/183 (25%), Positives = 75/183 (40%), Gaps = 12/183 (6%)

Query: 5   RDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFY 64
           RDE   + + E E   +ER   R    +    R   ++     +   R+ R   R +S +
Sbjct: 243 RDERLKKEKQEREEREKERERERE---ERERKRRREEEEREKERARDRERRKRSRSRSRH 299

Query: 65  SSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 124
           SS  +  R    RD+   R      ++   SRS     SRS+     K  S  + + R  
Sbjct: 300 SSRTSDRRCSRSRDHKRSRS-----RERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSK 354

Query: 125 VRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEA 184
            R   SYK +++    RD+E+  +S +  +  S    S+V S    +K S  T  E  E+
Sbjct: 355 SRDRKSYKHRSK---SRDREQDRKSKEKEKRGSDDKKSSVKSGS-REKQSEDTNTESKES 410

Query: 185 ASK 187
            +K
Sbjct: 411 DTK 413



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 46/165 (27%), Positives = 63/165 (38%), Gaps = 7/165 (4%)

Query: 4   RRDEMWSEGRYEYERIPRERAPPRS-HPSDESGYRWTRD-DHSASRQPEYRDMRDGFRRK 61
           RR+E   E     +R  R+R+  RS H S  S  R +R  DH  SR  E R  R   RR+
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332

Query: 62  SFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH 121
           S   SH   ER    R     R     RK   H            S E+ K  S      
Sbjct: 333 S--RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS---DDK 387

Query: 122 RKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSS 166
           + SV+ G+  K+  + N E  +      +  + +   S G   S+
Sbjct: 388 KSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 35/168 (20%), Positives = 64/168 (38%), Gaps = 5/168 (2%)

Query: 42  DHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSV 101
           D    ++ + R+ R+  R +        R R   +R+    R+    ++    SR  S  
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303

Query: 102 SSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSG 161
           S R  S  RS+ +   +S+ R+  R     + ++    ER      +  + S+     S 
Sbjct: 304 SDRRCS--RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361

Query: 162 SAVSSSKVLDKPSRLTEKELAEAASKWAAEK---LEKSDESNLPEISE 206
              S S+  ++  +  EKE   +  K ++ K    EK  E    E  E
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKE 409


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 10/101 (9%)

Query: 69  ARERSPYKRDNTFFRESPVGRKD-SPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRP 127
           +R R  Y R  +  R     R      SRSGSS SS S S  RS+S S  +S+ R   + 
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238

Query: 128 GASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSK 168
            +  K++   +P ++K         SR  S S+G + S SK
Sbjct: 239 RSRSKKEKSRSPSKEK---------SRSRSHSAGKSRSKSK 270



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 56/213 (26%), Positives = 82/213 (38%), Gaps = 33/213 (15%)

Query: 4   RRDEMWSEGR--YEYERIPRERAPPRSHP---------SDESGYRWTRDDHSASRQPEYR 52
           RRD  +  GR  Y Y R  R++  P +           S    ++  +D    + +  Y 
Sbjct: 74  RRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYA 133

Query: 53  DMRDGFRRKSF--YSSHYARERSPYKRDNTFFRESPVGRK-----DSPHSRSGSSVSSRS 105
           D   G + +    + S+   +R+  K D T       GRK     D P SR       RS
Sbjct: 134 DAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVN----GRKIRLVEDKPGSRR-----RRS 184

Query: 106 YSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVS 165
           YS  RS S S  +S+H +  R      R         K R  +S   SR  S S   + S
Sbjct: 185 YSRSRSHSRSRSRSRHSRKSR-----SRSGSSKSSHSKSRS-RSRSGSRSRSKSRSRSQS 238

Query: 166 SSKVLDKPSRLTEKELAEAASKWAAEKLEKSDE 198
            S+   + SR   KE + + S  A +   KS +
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 38/144 (26%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 20  PRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSS-HYARERSPYKRD 78
           P+ R+P R     +S  R      S  R+ E        R +S   S   +R RS  K  
Sbjct: 286 PKSRSPSRHKSKSKSRSR------SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG 339

Query: 79  NTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGN 138
           +     S    KD    R  S   SRS S  RSKS    +   ++  + G+S K++ E  
Sbjct: 340 SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399

Query: 139 PERDKERPVQSLKTSRDTSPSSGS 162
                  P +S+   R+ + S  S
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESS 423



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 44/208 (21%)

Query: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYK-RDN 79
           R  +  RSH    S  R +R   S S              KS +S   +R RS  + R  
Sbjct: 183 RSYSRSRSHSRSRSRSRHSRKSRSRSGSS-----------KSSHSKSRSRSRSGSRSRSK 231

Query: 80  TFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNP 139
           +  R     R     SRS S   SRS S    KS S  + Q  + ++   +  +    +P
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291

Query: 140 ERDK----------ERPVQ---------------SLKTSRDTSPSSGSAVSSSKVLDKP- 173
            R K          ER V+               SL+ SR  S S G + S S+   K  
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351

Query: 174 ------SRLTEKELAEAASKWAAEKLEK 195
                  R  E+  + + S+  +E+  K
Sbjct: 352 DKRKGRKRSREESRSRSRSRSKSERSRK 379



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 42/174 (24%), Positives = 63/174 (36%), Gaps = 23/174 (13%)

Query: 37  RWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSR 96
           R   D   + R+  Y   R   R +S  S H  + RS      +   +S    +    SR
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRS-RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229

Query: 97  SGSS-----------VSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKER 145
           S S              SRS S E+S+S S    + R   +  A  K QN  N  + K R
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289

Query: 146 PVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDES 199
                      SPS   + S S+   +  R+ E++    +   + EK  +   S
Sbjct: 290 -----------SPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRS 332



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 54/255 (21%), Positives = 95/255 (37%), Gaps = 27/255 (10%)

Query: 5   RDEMWSEGRYEYERIP-RERAPPRSHPS--------DESGYRWTRDDHSA---SRQPEYR 52
           R +  S  + E  R P +E++  RSH +        D++  +   +D+     SR P   
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294

Query: 53  DMRDGFRRKSFYSSHYARERSPYKRDNT---FFRESPVGRKDSPHSRSGSSVSSRSYSPE 109
             +   R +S        +R    R  +     R+S    +    SRS S   SRS S +
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR--SRSKSKD 352

Query: 110 RSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKV 169
           + K     + + R   R  +  +R  +   +RD +      K   DT  S   +      
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRS------ 406

Query: 170 LDKPSRLTEKELAEAASKWA-AEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTT 228
              PSR   KE   A S+ +  E   +S+ +   + +   + S +    + P E  S + 
Sbjct: 407 ---PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463

Query: 229 HGIELFEDSQLTTRS 243
              +    S+  +RS
Sbjct: 464 SASKTRSRSKSRSRS 478



 Score = 28.9 bits (63), Expect = 4.6
 Identities = 37/121 (30%), Positives = 48/121 (39%), Gaps = 9/121 (7%)

Query: 10  SEGRYEYERIPRERAPPRSHPSDESGYRWTRD-DHSASRQPEYRDMRDGFRRKSFYSSHY 68
           S  R + ER  R+R   R   +  S  +   D D S SR P     ++    KS  S   
Sbjct: 368 SRSRSKSER-SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQRE 426

Query: 69  ARERSPYKRDNTFFRE-SPVGRKDSPH------SRSGSSVSSRSYSPERSKSYSFHQSQH 121
            R  S     N   R  S    K  P+      SRS S+  +RS S  RS+S S   S+ 
Sbjct: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486

Query: 122 R 122
           R
Sbjct: 487 R 487


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 58/215 (26%), Positives = 74/215 (34%), Gaps = 17/215 (7%)

Query: 3   YRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRD-----G 57
           YRR    S           +  P RSH  +    R  R   S S  P  R  +      G
Sbjct: 485 YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544

Query: 58  FRRKSFYSSHYARERSPYKRDNTFFRESPVG----RKDSPHSRSGSSVSSRSYSPERSKS 113
            RR+S       R RSP        R +P      R  SP  R  S  S R YSP   + 
Sbjct: 545 RRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSP-SPRRYSPPIQRR 603

Query: 114 YSFHQSQHRKSVRPGASYKRQNEGNP---ERDKERPVQSLKTSRDTSPSSGSAVSSSKVL 170
           YS      R++  P    KR+   +P    R    P    ++S  T   S S  S  +  
Sbjct: 604 YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG 663

Query: 171 DKPSRLTEKELAEAASKWAAEKLEKSDESNLPEIS 205
             PSR T     EA S    ++   S     P+ S
Sbjct: 664 SSPSRSTR----EARSPQPNKRHSPSPRPRAPQTS 694



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 5/128 (3%)

Query: 76  KRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK-RQ 134
           KRD     E    R+    SRS     SRS SP R  S    + +   S  P    K R 
Sbjct: 153 KRDK---EEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRS 209

Query: 135 NEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLE 194
               PE+ ++ P     + +   PS   A S+S +L  P      E  E + +  ++K E
Sbjct: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK-E 268

Query: 195 KSDESNLP 202
           K  E   P
Sbjct: 269 KEKEKTRP 276



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 16/111 (14%)

Query: 129 ASYKRQNEGNPERDKERPVQS-----------LKTSRDTSPSSGSAVSSSKVLDKPSRLT 177
           AS K+Q+E   +RDKE    S            + SR  SP   S+    +     SR  
Sbjct: 142 ASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP 201

Query: 178 EKELAEAASKWAAEKLEKSDESNLPEI-----SEYEAGSTAPLFTDQPEEP 223
                  +   A EK EK+ E   P +     S  EA ST+ +      EP
Sbjct: 202 RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP 252


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 67/244 (27%), Positives = 96/244 (39%), Gaps = 25/244 (10%)

Query: 20  PRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYS----SHYARERS-- 73
           P  + P     S  S   ++R   S S  P  R     + R   YS    S Y R RS  
Sbjct: 277 PPYKEPSAYQSSTRSPSPYSRRQRSVS--PYSRRRSSSYERSGSYSGRSPSPYGRRRSSS 334

Query: 74  PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKR 133
           P+    +  R SP+  + S  SRS S   SR  S    K  S  +S+H  S+ P      
Sbjct: 335 PFLSKRSLSR-SPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRH-SSISPVRLPLN 392

Query: 134 QNEGN--PERDKERPVQSLKTSRDTSPSSGSAV-----SSSKVLDKPSRLTEKELAEAAS 186
            + G     + KER   +     D   S GS V      +S V  K S L  K+L  +  
Sbjct: 393 SSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSV- 451

Query: 187 KWAAEKLEKS-DESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKA 245
                KLEKS  ++ L  ++           T + +  E++  H ++  + +Q T  SK 
Sbjct: 452 -----KLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLK-AQGTRDSKP 505

Query: 246 IASK 249
           IA K
Sbjct: 506 IALK 509



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 57/202 (28%), Positives = 85/202 (42%), Gaps = 38/202 (18%)

Query: 4   RRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDH----SASRQPE------YRD 53
           R++     G  +  +  R+R  P+S+ + +S  R +R  H     +S+Q +      Y  
Sbjct: 185 RKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQ 244

Query: 54  MRDGFRRKSFYSSHY----------ARERS---PYKRDNTFFRESPVGRKDSPHSRSGSS 100
             D    +S  SS+Y          +R +S   PYK  + +   +   R  SP+SR   S
Sbjct: 245 DYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSST---RSPSPYSRRQRS 301

Query: 101 VSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDK----ERPVQSLKT--SR 154
           VS   YS  RS SY    S   +S  P   Y R+   +P   K      P+ S K+  SR
Sbjct: 302 VS--PYSRRRSSSYERSGSYSGRSPSP---YGRRRSSSPFLSKRSLSRSPLPSRKSMKSR 356

Query: 155 DTSPS-SGSAVSSSKVLDKPSR 175
             SP+ S  + S SK     SR
Sbjct: 357 SRSPAYSRHSSSHSKKKRSSSR 378


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 67/244 (27%), Positives = 96/244 (39%), Gaps = 25/244 (10%)

Query: 20  PRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYS----SHYARERS-- 73
           P  + P     S  S   ++R   S S  P  R     + R   YS    S Y R RS  
Sbjct: 277 PPYKEPSAYQSSTRSPSPYSRRQRSVS--PYSRRRSSSYERSGSYSGRSPSPYGRRRSSS 334

Query: 74  PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKR 133
           P+    +  R SP+  + S  SRS S   SR  S    K  S  +S+H  S+ P      
Sbjct: 335 PFLSKRSLSR-SPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRH-SSISPVRLPLN 392

Query: 134 QNEGN--PERDKERPVQSLKTSRDTSPSSGSAV-----SSSKVLDKPSRLTEKELAEAAS 186
            + G     + KER   +     D   S GS V      +S V  K S L  K+L  +  
Sbjct: 393 SSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSV- 451

Query: 187 KWAAEKLEKS-DESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKA 245
                KLEKS  ++ L  ++           T + +  E++  H ++  + +Q T  SK 
Sbjct: 452 -----KLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEKHLVKDLK-AQGTRDSKP 505

Query: 246 IASK 249
           IA K
Sbjct: 506 IALK 509



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 57/202 (28%), Positives = 85/202 (42%), Gaps = 38/202 (18%)

Query: 4   RRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDH----SASRQPE------YRD 53
           R++     G  +  +  R+R  P+S+ + +S  R +R  H     +S+Q +      Y  
Sbjct: 185 RKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQ 244

Query: 54  MRDGFRRKSFYSSHY----------ARERS---PYKRDNTFFRESPVGRKDSPHSRSGSS 100
             D    +S  SS+Y          +R +S   PYK  + +   +   R  SP+SR   S
Sbjct: 245 DYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSST---RSPSPYSRRQRS 301

Query: 101 VSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDK----ERPVQSLKT--SR 154
           VS   YS  RS SY    S   +S  P   Y R+   +P   K      P+ S K+  SR
Sbjct: 302 VS--PYSRRRSSSYERSGSYSGRSPSP---YGRRRSSSPFLSKRSLSRSPLPSRKSMKSR 356

Query: 155 DTSPS-SGSAVSSSKVLDKPSR 175
             SP+ S  + S SK     SR
Sbjct: 357 SRSPAYSRHSSSHSKKKRSSSR 378


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 48/183 (26%), Positives = 74/183 (40%), Gaps = 25/183 (13%)

Query: 20   PRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFY--SSHYARERSPYKR 77
            PR  +PPR  PSD            A   P       G  R S     + +  ER  Y  
Sbjct: 1224 PRASSPPRHPPSD-----------LAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEY-- 1270

Query: 78   DNTFFRESPVGRK---DSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQ 134
              T   + P  R+     P  ++  S   R++SP R++       + RKS   GA ++ Q
Sbjct: 1271 --TVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGA-FQAQ 1327

Query: 135  NEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLE 194
            +EG  ++  +   Q L+  R +SP+    V+      K + LT +  AE    W+ EK  
Sbjct: 1328 DEGRSQQPSQGQSQLLR--RQSSPAPSRQVTMLPA--KQAELTRRSQAEPPHPWSPEKRP 1383

Query: 195  KSD 197
            + D
Sbjct: 1384 EGD 1386



 Score = 28.1 bits (61), Expect = 7.9
 Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 31/168 (18%)

Query: 20  PRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPY---- 75
           PR     R +P   S  R TRD+ + S        RD  R     S + A   +P     
Sbjct: 575 PRTSCAQRDNPRASSPNRATRDNPTTSCA-----QRDNPRASRTSSPNRATRDNPRTSCA 629

Query: 76  KRDNTFFRESPVGR---KDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 132
           +RDN   R S   R   +DSP +        R+ SP R+      Q   R S        
Sbjct: 630 QRDNP--RASSPNRTTQQDSPRTSCARRDDPRASSPNRT----IQQENPRTSCAL----- 678

Query: 133 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 180
                   RD  R     +T +  +P +  A         P+R T++E
Sbjct: 679 --------RDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQE 718


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 40/181 (22%)

Query: 18  RIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKR 77
           R+ R R+P  +          T+  HS SR P++R  R   R        + R RSP +R
Sbjct: 480 RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQR--------WGRSRSPQRR 531

Query: 78  DNTFFRESP---------------VGRKDSPHSRS----GSSVS--------SRSYSPER 110
             +   + P                 R+   HSRS    G S S        SRS +P R
Sbjct: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591

Query: 111 SKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKER---PVQSLKTSRDTSPSSGSAVSSS 167
            +S S   ++ R   R  A   R     P R + R   PV+  + SR  SP+  S  S S
Sbjct: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR--RRSRSRSPARRSGRSRS 649

Query: 168 K 168
           +
Sbjct: 650 R 650



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 60/232 (25%), Positives = 88/232 (37%), Gaps = 31/232 (13%)

Query: 10  SEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMR--DGFRRKS----- 62
           S  R    R  R R P R      +  R  R   S SR P  R  R     RR+S     
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGR---SRSRTPARRRSRTRSPVRRRSRSRSP 640

Query: 63  FYSSHYARERSPYKRDNTFFRESPV----GRKDSPHSRSGSSVS--------SRSYSPER 110
              S  +R R+P +R  +  R +P      R  +P  RSG S S        SRS +P R
Sbjct: 641 ARRSGRSRSRTPARRGRSRSR-TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRR 699

Query: 111 SKSYS--------FHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGS 162
            +S S         H    ++  R G+S +R+N+    + + R   S +  +    S  S
Sbjct: 700 GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS 759

Query: 163 AVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 214
              SS      SRL+ +     +S    +K +     +    S+ +A S  P
Sbjct: 760 RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811



 Score = 35.8 bits (81), Expect = 0.038
 Identities = 42/178 (23%), Positives = 74/178 (41%), Gaps = 16/178 (8%)

Query: 72  RSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASY 131
           RSP  +     ++   GR+    S S S    R  S ++ K  S  +S+ RK   P    
Sbjct: 181 RSPTPKQKKKKKKKDRGRR----SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKS 236

Query: 132 KRQNEGNPERDKERPV----QSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 187
           KR+++ + +R + R      +S +  R TS  S S+  +S+   + S   +      A +
Sbjct: 237 KRKSK-DKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR-SAAAKTHTTALAGR 294

Query: 188 WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKA 245
             +    +  E + P     E G+T+   T +P  PE+ T      +ED     + K+
Sbjct: 295 SPSPASGRRGEGDAP---FSEPGTTS---TQRPSSPETATKQPSSPYEDKDKDKKEKS 346



 Score = 35.0 bits (79), Expect = 0.065
 Identities = 42/147 (28%), Positives = 55/147 (37%), Gaps = 12/147 (8%)

Query: 18   RIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMR-DGFRRKSFYSSHYARERSPYK 76
            R P  R   RS P      R +R   SAS  PE R       RR    SS    E+S   
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742

Query: 77   RDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNE 136
            R     R S    +    SR G S S +    +RS+S S      R+  R   + +R   
Sbjct: 1743 RR----RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS-----RREKTR--TTRRRDRS 1791

Query: 137  GNPERDKERPVQSLKTSRDTSPSSGSA 163
            G+ +    R  +S   SR T    G +
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGS 1818



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 47/205 (22%), Positives = 75/205 (36%), Gaps = 24/205 (11%)

Query: 21   RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80
            R+R+   S P  +S  R +     +   PE +D               A  R+    D++
Sbjct: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD------------KPRAAPRAQSGSDSS 1621

Query: 81   FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH-------RKSVRPGASYKR 133
               ++P  R     SRSGSS   R  SPE S S +    +H       R+  R     K 
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS-TESSPEHPPKSRTARRGSRSSPEPKT 1680

Query: 134  QNEGNPERDKERPVQSL----KTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWA 189
            ++   P R   R    L    + SR +  +S S  + S+   +  R       E A K  
Sbjct: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740

Query: 190  AEKLEKSDESNLPEISEYEAGSTAP 214
            + +  +S  S   + +     S +P
Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSP 1765



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 37/169 (21%), Positives = 61/169 (36%), Gaps = 5/169 (2%)

Query: 84  ESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDK 143
           + P      P+S    S SSRS +P++ K     + + R      +S +R+ + + ++ K
Sbjct: 161 KQPAPEPPKPYSLVRESSSSRSPTPKQKKK---KKKKDRGRRSESSSPRRERKKSSKKKK 217

Query: 144 ERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLT--EKELAEAASKWAAEKLEKSDESNL 201
            R     K  +  SP+  S   S     K SR T    +   A    +A+    SD S  
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277

Query: 202 PEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKT 250
              S      T  L    P         G   F +   T+  +  + +T
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326



 Score = 31.6 bits (70), Expect = 0.72
 Identities = 56/227 (24%), Positives = 83/227 (36%), Gaps = 31/227 (13%)

Query: 29   HPSDESGYRWTRDDHSASR--QPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESP 86
            H SD S     R  HS S   Q + +    G R +S         RSP ++D   F  SP
Sbjct: 1067 HRSDTSSPE-VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASP 1125

Query: 87   VGRKDSPHSRSGSSVSSRSYSPERSKS------YSFHQSQHRKSVRP----GASYKRQNE 136
            + +      +S     S SY    S S          +S+ + ++ P     AS  RQ +
Sbjct: 1126 MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKD 1185

Query: 137  G-NPERDKERPVQSL--KTSRDTSPSSGSAVSSSKVLDK-----PSRLTEKELAEAASK- 187
              +P   ++RP  SL  K +  T P   S   SS    +     P+   ++EL E   K 
Sbjct: 1186 KFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKS 1245

Query: 188  ---------WAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPES 225
                       + +L++   SN     E E      L  DQ +   S
Sbjct: 1246 EEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQAS 1292



 Score = 31.2 bits (69), Expect = 0.93
 Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 17/132 (12%)

Query: 89   RKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS----VRPGASYKRQ---------- 134
            R+ S  S S SS SS S S   S S S   S   +     V+P  + KR           
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589

Query: 135  -NEGNPERDK--ERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAE 191
              EG P      +R  +S  +S  +S SS S+ SSS      S  +    + ++S  ++ 
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 192  KLEKSDESNLPE 203
               K     LP+
Sbjct: 2650 SPAKPGPQALPK 2661



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 6/121 (4%)

Query: 133  RQNEGNPE-RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAE 191
            R +  +PE R       SL++   TSP  G + SSS V +  SR     + +   +++A 
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASR---SPIRQDRGEFSAS 1124

Query: 192  KLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTK 251
             + KS  S  PE S +++ S++    D       +     E  E   L  +  A AS  +
Sbjct: 1125 PMLKSGMS--PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPR 1182

Query: 252  E 252
            +
Sbjct: 1183 Q 1183



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 49/210 (23%), Positives = 76/210 (36%), Gaps = 27/210 (12%)

Query: 21   RERAPPRSHPSDESGYRWTRDDHSAS-RQPEYRDMRDGFRRKSFYSSHYARERSPY--KR 77
            RER+   S P  + G   T    S S   P  RD      R S   S    +  P    R
Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSR 1475

Query: 78   DNTFFRESP----VGRKDSPHSRSGSS--VSSRSYSPERSKSYSFHQ------------- 118
              +    SP    + +   P SRS SS  ++++  +P+R +S S                
Sbjct: 1476 GRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQ 1535

Query: 119  -----SQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKP 173
                 S     V+P AS + ++E +   D +   ++    R  S SS    S S++  + 
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR 1595

Query: 174  SRLTEKELAEAASKWAAEKLEKSDESNLPE 203
            SR       +   + A      SD S  P+
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 42/174 (24%), Positives = 59/174 (33%), Gaps = 18/174 (10%)

Query: 18  RIPRERAPPRSH-PSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYK 76
           R P  R   RS  P+  SG   +R      R       R   R +S      +  R+P +
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720

Query: 77  RDNTFFRESPVGRKDSPHSRSGSSVS------------SRSYSPERSKSYSFHQSQHRKS 124
           R  +        +  +   RS S+ S            SRS S  RSK+ S  +   R+S
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS--RLSLRRS 778

Query: 125 VRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDK---PSR 175
           +   +   +Q    P R         K    T P    + SS     K   PSR
Sbjct: 779 LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832



 Score = 28.9 bits (63), Expect = 4.6
 Identities = 48/231 (20%), Positives = 79/231 (34%), Gaps = 28/231 (12%)

Query: 21   RERAPPR-------SHPSDESGYRWTRDDHSASRQPEYRDMRDGFR--------RKSFYS 65
            R R PPR       S P      R +R   SAS        R G          ++S   
Sbjct: 1717 RSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776

Query: 66   SHYARERSPYKRDNTFFRESPVGRKDSPHSRS--------GSSVSSRSYSPERSKSYSFH 117
            S   + R+  +RD +   +S   R+    SRS        GS   SRS + + S   S  
Sbjct: 1777 SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR 1836

Query: 118  QSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLT 177
            + + R    P +  + ++  +P   K    ++   +   S S    +S  +     SR  
Sbjct: 1837 RRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR-----SRSR 1891

Query: 178  EKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTT 228
               ++   S+       +   S    +S   + S  P  T +     + TT
Sbjct: 1892 TSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 57/214 (26%), Positives = 80/214 (37%), Gaps = 36/214 (16%)

Query: 11  EGRYEYERIP-----RERAPPRS----HPSDESGYRWTRD-DHSASRQPEYRDMRDGFRR 60
           EGRYE  R+      RERA   S    H     G+  TR  D    R P  R ++ G   
Sbjct: 126 EGRYE-RRLDGASDNRERAYEHSAYGHHERGTGGFDRTRHYDQDYYRDPRERTLQHGL-- 182

Query: 61  KSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHS--------RSGSSVSSRSYSPERSK 112
             +Y+S   R RSP + D    R  P  R+             R   +   R   PER+ 
Sbjct: 183 --YYAS---RSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRRPERNY 237

Query: 113 SYSFHQSQHRKSVRPGASYK---------RQNEGNPERDKERPVQSLKTSRDTSPSSGSA 163
            +S  +S H    R  +  +         R   G+  R +     S+ +S  TS  S  +
Sbjct: 238 QHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDS 297

Query: 164 VSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSD 197
            SSS   D P+R  +     A +      LEK +
Sbjct: 298 SSSSSD-DSPARSVQSAAVPAPTSQLLSSLEKDE 330


>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
          Length = 1648

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 93   PHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKT 152
            P SRS S+ SSRS    + K  S    + R   R  +  +     +P   +ERP +  + 
Sbjct: 988  PPSRSRSTSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEERPRR--QR 1045

Query: 153  SRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYE 208
            S+  S  S S  SSS+   K  +  +K        W   +      S  P  S YE
Sbjct: 1046 SKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 15/120 (12%)

Query: 53   DMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSP---- 108
            ++R   R +S  SS  +R+++  KR +     +  G +     RS     SRS SP    
Sbjct: 985  ELRPPSRSRSTSSSR-SRKKAKRKRVSREHGRTRSGTRSESRDRS-----SRSASPSVGE 1038

Query: 109  -----ERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSA 163
                 +RSK+ S   S  R S R  A  K+  + + E  +     S +TSR  S S GS+
Sbjct: 1039 ERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSS 1098


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 55/233 (23%), Positives = 86/233 (36%), Gaps = 16/233 (6%)

Query: 18  RIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDM------RDGFRRKSFYSSHYARE 71
           R  RER   RSH   E G R T   +S S +  Y D          +R ++ YS  Y   
Sbjct: 395 RSERERRRSRSHSRSERGSR-TNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDN 453

Query: 72  RSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSP-----ERSKSYSFHQSQHRKSVR 126
           R+    D+    +    R+ S HS S   + + SYS      +   SY   + + + S +
Sbjct: 454 RARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSK 513

Query: 127 PGASYKRQNEGNPERDKERPVQSLKTSRDTSPS--SGSAVSSSKVLDKPSRLTEKELAEA 184
                KR +E    +    P   L   R +S S    SA      L KP   ++K     
Sbjct: 514 LERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSF 573

Query: 185 ASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDS 237
                 E++++S   +L   +    GS   +    PE  ++ +        DS
Sbjct: 574 CCTELNEEIKQSHSFSLQ--TPCSKGSELRMINKNPEREKAGSPAPSNRLNDS 624


>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing A [Homo sapiens]
          Length = 312

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 38/115 (33%), Positives = 50/115 (43%), Gaps = 12/115 (10%)

Query: 32  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKD 91
           DE   R    DH   R+  YRD+ D  RR        +R RSP +R  +  R SP  R++
Sbjct: 201 DEKLERVPSPDH---RRRSYRDL-DKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRE 256

Query: 92  SPHSRSGSSVSSRSYS---PERSKSYSFHQSQHRKS-----VRPGASYKRQNEGN 138
              S+S     SRS       RSKS   H+S   +S      R   S+K+   GN
Sbjct: 257 RHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGN 311


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 15/147 (10%)

Query: 3    YRRDEMWSEGRYEYERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKS 62
            Y R   +S+  Y        R   RSH SD+S Y  ++     S++ +Y    D +    
Sbjct: 883  YSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKH---RSKRHKYSSSDDDYS--- 936

Query: 63   FYSSHYARERSPYKRDNTFFRESPVGR-KDSPHSRSGSSVSSRS---YSPERSKSYSFHQ 118
              S   +R RS   R +T  R    GR + S  SRS S   SRS   +S +RS+SYS  +
Sbjct: 937  -LSCSQSRSRS---RSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDR 992

Query: 119  SQHRKSVRPGASYKRQNEGNPERDKER 145
            S+  +S    +  ++++ G+ E  +ER
Sbjct: 993  SRSTRSPSQRSGSRKRSWGH-ESPEER 1018



 Score = 35.0 bits (79), Expect = 0.065
 Identities = 51/177 (28%), Positives = 69/177 (38%), Gaps = 24/177 (13%)

Query: 3    YRRDEMWSEGRYEYERIPRERAPPR--SHPSDESGYRWTRDDHSA----SRQ-----PEY 51
            Y  +E   +   E+ R  R R+  R  SH S    Y  + D  S     SRQ       Y
Sbjct: 836  YSEEEEEEDSGSEHSR-SRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSY 894

Query: 52   RDMRDGFRRKSFYS-----SHYARERSPYKRDNTFFRESPVGRKDSP-HSRSGSSVSSRS 105
             D  D  RR S  S     S YA  +   KR      +       S   SRS S    RS
Sbjct: 895  SDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERS 954

Query: 106  YSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGS 162
             S  RS+S S  +S+ ++  R   ++  Q   +  RD+ R      ++R  S  SGS
Sbjct: 955  RSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR------STRSPSQRSGS 1005


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 42/131 (32%), Positives = 52/131 (39%), Gaps = 23/131 (17%)

Query: 21   RERAPPRSHPSDESGYRW-TRD---DHSASRQPEYRDMRDGFRRKSF--------YSSHY 68
            + R+P RS    E+  R  TR     HS SR    R     +R +S+        YS   
Sbjct: 1310 QSRSPSRSRSKSETKSRHRTRSVSYSHSRSRS---RSSTSSYRSRSYSRSRSRGWYSRGR 1366

Query: 69   ARERSP----YKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 124
             R RS     YK   T  R         PHSRS S      YS  RS+S    +SQ   S
Sbjct: 1367 TRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRS----RSQRSDS 1422

Query: 125  VRPGASYKRQN 135
               G SY R++
Sbjct: 1423 YHRGRSYNRRS 1433



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 50/234 (21%), Positives = 100/234 (42%), Gaps = 29/234 (12%)

Query: 44  SASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRD----NTFFRESPVGRKDSPHSRSGS 99
           S++R+ +    R+   R S  SSH++ +R   K D    ++    S    +   HS+S S
Sbjct: 470 SSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYS 529

Query: 100 SVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPER-----DKERPVQSLKTSR 154
             SSRS +  +S S+S  +S+ R S + G  ++++   +P +      + +PV++ +  R
Sbjct: 530 RGSSRSRTASKSSSHSRSRSKSRSSSKSG--HRKRASKSPRKTASQLSENKPVKT-EPLR 586

Query: 155 DTSPSSGSAVSSSKVLDK-----------PSRLTEKELAEAASKWAAEKLEKSDESNLPE 203
            T   + + V    V +            PSR    +     S    ++++      LP 
Sbjct: 587 ATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPI 646

Query: 204 ISEY------EAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTK 251
            S Y      E GS++     +       +T+       S+ + RS++ +S+++
Sbjct: 647 QSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSR 700



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 47/214 (21%), Positives = 82/214 (38%), Gaps = 8/214 (3%)

Query: 16  YERIPRERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPY 75
           YERI   +A        +S Y       + S    ++  ++    +S YS +  R     
Sbjct: 630 YERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESS 689

Query: 76  KRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQN 135
            R  +    S    +    SRS +S  SRS SP  S+S+S ++          +SY   +
Sbjct: 690 PRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPS-SRSHSRNKYSDHSQCSRSSSYTSIS 748

Query: 136 EGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEK 195
             +  R K R    L++S   +  S    SSS      S+  +     +  +  +E    
Sbjct: 749 SDDGRRAKRR----LRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSS 804

Query: 196 SDESNLPEISEYEAGSTAPLFTDQPEEPESNTTH 229
            D S+  E S  +A  +A    ++ ++ +   TH
Sbjct: 805 LDYSSDSEQSSVQATQSA---QEKEKQGQMERTH 835



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 11/98 (11%)

Query: 31   SDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYS--SHYARERSPYK--RDNTFFRESP 86
            S  S YR  +   ++SR        D   R   Y+  S+Y+R RS  +  R +++ R   
Sbjct: 1369 SRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHR--- 1425

Query: 87   VGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKS 124
             GR  +  SRS  S  S S   E  +SYS H+S    S
Sbjct: 1426 -GRSYNRRSRSCRSYGSDS---ESDRSYSHHRSPSESS 1459



 Score = 28.5 bits (62), Expect = 6.1
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 71   ERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGAS 130
            E++P + D++  R SP   +    ++S     S SYS  RS+S S   S   +S     S
Sbjct: 1300 EQTPSRDDDSQSR-SPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRS 1358

Query: 131  YKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVS 165
                + G   R +    +S K+ R +S S   + S
Sbjct: 1359 RGWYSRGR-TRSRSSSYRSYKSHRTSSRSRSRSSS 1392


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 51/208 (24%), Positives = 76/208 (36%), Gaps = 18/208 (8%)

Query: 28   SHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPV 87
            +H S ++G  W +   + S   EY D R   R     S   +  R P  R  T+ RE   
Sbjct: 2495 THSSVQAG-GWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSK 2553

Query: 88   GRKDSPH----SRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNE----GNP 139
                 P      R+GSS S  S S E S+       +H  S+  G    ++N+    G  
Sbjct: 2554 HSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSI-SGTKQSKENQVSAKGTW 2612

Query: 140  ERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSD-E 198
             + KE       ++  T  S  +  + SK L         ++A A SK     +   D  
Sbjct: 2613 RKIKENEFSPTNSTSQTVSSGATNGAESKTL-------IYQMAPAVSKTEDVWVRIEDCP 2665

Query: 199  SNLPEISEYEAGSTAPLFTDQPEEPESN 226
             N P       G+T P+     E+   N
Sbjct: 2666 INNPRSGRSPTGNTPPVIDSVSEKANPN 2693


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.122    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,941,455
Number of Sequences: 37866
Number of extensions: 529815
Number of successful extensions: 3209
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 2395
Number of HSP's gapped (non-prelim): 793
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.