Guide to the Human Genome
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Search of human proteins with 41349482

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
         (331 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   749   0.0  
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    664   0.0  
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...   483   e-136
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...   362   e-100
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...   341   6e-94
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...   294   8e-80
gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]   195   5e-50
gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]   192   3e-49
gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]     192   3e-49
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]              176   2e-44
gi|160707881 formin 2 [Homo sapiens]                                  150   1e-36
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     150   2e-36
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   145   4e-35
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   145   4e-35
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   145   4e-35
gi|163965366 nascent polypeptide-associated complex alpha subuni...   145   5e-35
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      144   1e-34
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     144   1e-34
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...   144   1e-34
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   141   9e-34
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   141   9e-34
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   141   9e-34
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...   140   2e-33
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...   140   2e-33
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...   139   3e-33
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   136   2e-32
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   136   2e-32
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                136   3e-32
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...   135   7e-32
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          135   7e-32

>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  749 bits (1933), Expect = 0.0
 Identities = 331/331 (100%), Positives = 331/331 (100%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
           PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
           PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180

Query: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240
           GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240

Query: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 300
           QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 300

Query: 301 GNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
           GNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ
Sbjct: 301 GNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  664 bits (1713), Expect = 0.0
 Identities = 315/416 (75%), Positives = 322/416 (77%), Gaps = 85/416 (20%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQG---------------------P 39
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQG                     P
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP 60

Query: 40  SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 99
            PQGGN+PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG
Sbjct: 61  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120

Query: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD-KSRSPRSPPGKP 158
           PPPQGGNQPQGPPPPPGKPQGPPPQGGN+PQGPPPPGKPQGPPPQGD KSRS RSPPGKP
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP 180

Query: 159 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD-KSRSSQSPPG 217
           QGPPPQGGNQPQGPPPPPGKPQGPPPQGG KPQGPPPPGKPQGPPPQGD KS+S++SPPG
Sbjct: 181 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG 240

Query: 218 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277
           KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP QGGSKS+S+RSP
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300

Query: 278 PGKPQGPPQQEGNNPQGPPPPAG------------------------------------- 300
           PGKPQGPP Q GN PQGPPPP G                                     
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360

Query: 301 -------GNPQQ------------------PQAPPAGQPQGPPRPPQGGRPSRPPQ 331
                  G PQQ                  PQAPPAGQPQGPPRPPQGGRPSRPPQ
Sbjct: 361 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score =  483 bits (1242), Expect = e-136
 Identities = 226/320 (70%), Positives = 253/320 (79%), Gaps = 19/320 (5%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQ+LNEDVSQEESPS+I+G P+G  PQGGN+PQ  PPPPGKP+G 
Sbjct: 1   MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGR 60

Query: 61  PPQGGNKPQGPPP-PGKPQGPPPQG-DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP 118
           PPQGGN+ QGPPP PGKP+GPPPQG ++S+ P   PGKP+G PPQGGNQ QGPPP PGKP
Sbjct: 61  PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP 120

Query: 119 QGPPPQGGNRPQGPPP-PGKPQGPPPQ-GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 176
           +GPPPQGGN+ QGPPP PGKP+GPPPQ G++S+ P   PGKP+GPPPQGGNQ QGPPP P
Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHP 180

Query: 177 GKPQGPPPQGGKKPQGPPP-PGKPQGPPPQGDKSRSSQSP-PGKPQGPPPQGGNQPQGPP 234
           GKP+GPPPQGG + QGPPP PGKP+GPPPQG        P PGKP+GPP QGGN+PQGPP
Sbjct: 181 GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPP 240

Query: 235 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 294
           P PGKPQGPPPQ GNKPQ PPPPG+PQGPP  GG+  Q    P GKPQGP          
Sbjct: 241 PHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGP---------- 290

Query: 295 PPPPAGGNPQQPQAPPAGQP 314
           PPPP GG P +   PP GQP
Sbjct: 291 PPPPQGGRPHR---PPQGQP 307



 Score =  335 bits (860), Expect = 3e-92
 Identities = 155/239 (64%), Positives = 177/239 (74%), Gaps = 23/239 (9%)

Query: 24  SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPP 82
           +Q + P    G P+G  PQGGN+ QGPPP PGKP+GPPPQGGN+ QGPPP PGKP+GPPP
Sbjct: 87  NQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 146

Query: 83  Q-GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP-PGKPQG 140
           Q G++S+ P   PGKP+GPPPQGGNQ QGPPP PGKP+GPPPQGGN+ QGPPP PGKP+G
Sbjct: 147 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG 206

Query: 141 PPPQ-GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKP 199
           PPPQ G++S+ P   PGKP+GPP QGGN+PQGPPP PGKPQGPPPQ G KPQ PPPPG+P
Sbjct: 207 PPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRP 266

Query: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQGPPP 256
           QGPPP          P G PQ P P    +PQGPPPPP  G+P  P       PQG PP
Sbjct: 267 QGPPP----------PGGNPQQPLPPPAGKPQGPPPPPQGGRPHRP-------PQGQPP 308


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score =  362 bits (930), Expect = e-100
 Identities = 161/185 (87%), Positives = 164/185 (88%), Gaps = 11/185 (5%)

Query: 147 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQG 206
           +  SP    G PQGP PQGGN+PQGPPPPPGKPQGPPPQGG KPQGPPPPGKPQGPPPQG
Sbjct: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84

Query: 207 DKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQ 266
           DKSRS +SPPGKPQGPPPQG           GKPQGPPPQGGNKPQGPPPPGKPQGPPAQ
Sbjct: 85  DKSRSPRSPPGKPQGPPPQG-----------GKPQGPPPQGGNKPQGPPPPGKPQGPPAQ 133

Query: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326
           GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP
Sbjct: 134 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 193

Query: 327 SRPPQ 331
           SRPPQ
Sbjct: 194 SRPPQ 198



 Score =  354 bits (909), Expect = 5e-98
 Identities = 170/208 (81%), Positives = 174/208 (83%), Gaps = 16/208 (7%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
           PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG           GKPQG
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG-----------GKPQG 109

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQ-GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP-GK 178
           PPPQGGN+PQGPPPPGKPQGPP Q G KS+S RSPPGKPQGPP Q GN PQGPPPP  G 
Sbjct: 110 PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 169

Query: 179 PQGPPPQGGKKPQGPPPP---GKPQGPP 203
           PQ P      +PQGPP P   G+P  PP
Sbjct: 170 PQQPQAPPAGQPQGPPRPPQGGRPSRPP 197



 Score =  291 bits (746), Expect = 4e-79
 Identities = 134/184 (72%), Positives = 142/184 (77%), Gaps = 16/184 (8%)

Query: 86  KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQG 145
           +  SP    G PQGP PQGGN+PQGPPPPPGKPQGPPPQGGN+PQGPPPPGKPQGPPPQG
Sbjct: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84

Query: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205
           DKSRSPRSPPGKPQGPPPQG           GKPQGPPPQGG KPQGPPPPGKPQGPP Q
Sbjct: 85  DKSRSPRSPPGKPQGPPPQG-----------GKPQGPPPQGGNKPQGPPPPGKPQGPPAQ 133

Query: 206 -GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPP---GKP 260
            G KS+S++SPPGKPQGPP Q GN PQGPPPP  G PQ P      +PQGPP P   G+P
Sbjct: 134 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 193

Query: 261 QGPP 264
             PP
Sbjct: 194 SRPP 197



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 31/62 (50%), Positives = 35/62 (56%), Gaps = 4/62 (6%)

Query: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
           S+ +S     G PQGP  Q GN PQGPPPP G  PQ P      +PQGPP P   G+P  
Sbjct: 24  SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPG-KPQGPPPQGGNKPQGPPPP---GKPQG 79

Query: 329 PP 330
           PP
Sbjct: 80  PP 81


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score =  341 bits (874), Expect = 6e-94
 Identities = 158/227 (69%), Positives = 174/227 (76%), Gaps = 30/227 (13%)

Query: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
           GKP+G  PQGGN+PQ PPPP                   PGKPQGPPPQGGNQ QGPPPP
Sbjct: 34  GKPEGRRPQGGNQPQRPPPP-------------------PGKPQGPPPQGGNQSQGPPPP 74

Query: 176 PGKPQGPPPQGGKKPQGPPP-PGKPQGPPPQ-GDKSRSSQSPPGKPQGPPPQGGNQPQGP 233
           PGKP+G PPQGG + QGPPP PGKP+ PPPQ G++S+ +  PPGKP+ PPPQGGNQ   P
Sbjct: 75  PGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRP 134

Query: 234 PPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 292
           PPPPGKP+ PPPQGGN+ QGPPP PGKP+GPP Q G+KS+SARSPPGKPQGPPQQEGN P
Sbjct: 135 PPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKP 194

Query: 293 QGP--------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
           QGP        PPPAGGNPQQPQAPPAG+PQGPP PPQGGRP RP Q
Sbjct: 195 QGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQ 241



 Score =  333 bits (853), Expect = 2e-91
 Identities = 170/271 (62%), Positives = 189/271 (69%), Gaps = 32/271 (11%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSA++ +EDVSQEES  LI+G                     KP+G 
Sbjct: 1   MLLILLSVALLALSSAESSSEDVSQEESLFLISG---------------------KPEGR 39

Query: 61  PPQGGNKPQGPPPP-GKPQGPPPQG-DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP 118
            PQGGN+PQ PPPP GKPQGPPPQG ++S+ P  PPGKP+G PPQGGNQ QGPPP PGKP
Sbjct: 40  RPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKP 99

Query: 119 QGPPPQGGNRPQG-PPPPGKPQGPPPQG-DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 176
           + PPPQGGN+ QG PPPPGKP+ PPPQG ++S  P  PPGKP+ PPPQGGNQ QGPPP P
Sbjct: 100 ERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHP 159

Query: 177 GKPQGPPPQGGKKPQGP-PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235
           GKP+GPPPQ G K +    PPGKPQGPP Q         PPGKPQGPPP GGN  Q   P
Sbjct: 160 GKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAP 219

Query: 236 PPGKPQG--PPPQGGNKPQGPPPPGKPQGPP 264
           P GKPQG  PPPQGG     PP P + Q PP
Sbjct: 220 PAGKPQGPPPPPQGGR----PPRPAQGQQPP 246



 Score =  309 bits (792), Expect = 2e-84
 Identities = 145/229 (63%), Positives = 162/229 (70%), Gaps = 19/229 (8%)

Query: 95  GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG-PPPPGKPQGPPPQ-GDKSRSPR 152
           GKP+G  PQGGNQPQ PPPPPGKPQGPPPQGGN+ QG PPPPGKP+G PPQ G++S+ P 
Sbjct: 34  GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPP 93

Query: 153 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP-QGPPPPGKPQGPPPQGDKSRS 211
             PGKP+ PPPQGGNQ QG PPPPGKP+ PPPQGG +  + PPPPGKP+ PPPQG     
Sbjct: 94  PHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQ 153

Query: 212 SQSP-PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
              P PGKP+GPPPQ GN+ +    PPGKPQGPP Q GNKPQGPPPPGKPQGPP  GG+ 
Sbjct: 154 GPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP 213

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 319
            Q    P GKPQGP          PPPP GG P +P      Q Q PP+
Sbjct: 214 QQPQAPPAGKPQGP----------PPPPQGGRPPRP-----AQGQQPPQ 247



 Score =  134 bits (336), Expect = 1e-31
 Identities = 72/134 (53%), Positives = 76/134 (56%), Gaps = 28/134 (20%)

Query: 24  SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK----------PQGPPP 73
           +Q   P    G P+ P PQGGN+ QGPPP PGKP+GPPPQ GNK          PQGPP 
Sbjct: 129 NQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQ 188

Query: 74  P--GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
               KPQGPP           PPGKPQGPPP GGN  Q   PP GKPQGPPP     PQG
Sbjct: 189 QEGNKPQGPP-----------PPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPP----PQG 233

Query: 132 PPPPGKPQG-PPPQ 144
             PP   QG  PPQ
Sbjct: 234 GRPPRPAQGQQPPQ 247



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 32/71 (45%), Positives = 38/71 (53%), Gaps = 11/71 (15%)

Query: 269 SKSQSARSPPGKPQGPPQQEGNNPQGP---------PPPAGGNPQQPQAPPAGQPQGPPR 319
           S+ +S     GKP+G   Q GN PQ P         PPP GGN  Q   PP G+P+G  R
Sbjct: 24  SQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEG--R 81

Query: 320 PPQGGRPSRPP 330
           PPQGG  S+ P
Sbjct: 82  PPQGGNQSQGP 92


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score =  294 bits (752), Expect = 8e-80
 Identities = 146/187 (78%), Positives = 152/187 (81%), Gaps = 24/187 (12%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP-------- 112
           PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG +PQGPP        
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG-KPQGPPAQGGSKSQ 119

Query: 113 ---PPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP-GKPQGP--PPQGG 166
               PPGKPQGPP Q GN PQGPPPP         G   + P++PP G+PQGP  PPQGG
Sbjct: 120 SARSPPGKPQGPPQQEGNNPQGPPPPA--------GGNPQQPQAPPAGQPQGPPRPPQGG 171

Query: 167 NQPQGPP 173
            +P  PP
Sbjct: 172 -RPSRPP 177



 Score =  267 bits (683), Expect = 8e-72
 Identities = 130/175 (74%), Positives = 133/175 (76%), Gaps = 30/175 (17%)

Query: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226
           +Q + P    G PQGP PQGG KPQG         PPP          PPGKPQGPPPQG
Sbjct: 24  SQEESPSLIAGNPQGPSPQGGNKPQG---------PPP----------PPGKPQGPPPQG 64

Query: 227 GNQPQGPPPPPGKPQGPPPQGGN---------KPQGPPPPG-KPQGPPAQGGSKSQSARS 276
           GN+PQGPPPP GKPQGPPPQG           KPQGPPP G KPQGPPAQGGSKSQSARS
Sbjct: 65  GNKPQGPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARS 123

Query: 277 PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
           PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ
Sbjct: 124 PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 178



 Score =  230 bits (586), Expect = 2e-60
 Identities = 113/165 (68%), Positives = 120/165 (72%), Gaps = 28/165 (16%)

Query: 86  KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQG 145
           +  SP    G PQGP PQGGN+PQGPPPPPGKPQGPPPQGGN+PQGPPPPGKPQGPPPQG
Sbjct: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 84

Query: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPP-----------PPPGKPQGPPPQGGKKPQGPP 194
           DKSRSPRSPPGKPQGPPPQGG +PQGPP            PPGKPQGPP Q G  PQGPP
Sbjct: 85  DKSRSPRSPPGKPQGPPPQGG-KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 143

Query: 195 PP--GKPQGPPPQGDKSRSSQSPP-GKPQGP--PPQGGNQPQGPP 234
           PP  G PQ P          Q+PP G+PQGP  PPQGG +P  PP
Sbjct: 144 PPAGGNPQQP----------QAPPAGQPQGPPRPPQGG-RPSRPP 177



 Score =  197 bits (501), Expect = 1e-50
 Identities = 104/174 (59%), Positives = 112/174 (64%), Gaps = 35/174 (20%)

Query: 106 NQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
           +Q + P    G PQGP PQGGN         KPQGPPP          PPGKPQGPPPQG
Sbjct: 24  SQEESPSLIAGNPQGPSPQGGN---------KPQGPPP----------PPGKPQGPPPQG 64

Query: 166 GNQPQGPPPPPGKPQGPPPQGGK---------KPQGPPPP-GKPQGPPPQ-GDKSRSSQS 214
           GN+PQGPPPP GKPQGPPPQG K         KPQGPPP  GKPQGPP Q G KS+S++S
Sbjct: 65  GNKPQGPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARS 123

Query: 215 PPGKPQGPPPQGGNQPQGPPPPP-GKPQGPPPQGGNKPQGPPPP---GKPQGPP 264
           PPGKPQGPP Q GN PQGPPPP  G PQ P      +PQGPP P   G+P  PP
Sbjct: 124 PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 177


>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score =  195 bits (495), Expect = 5e-50
 Identities = 108/200 (54%), Positives = 122/200 (61%), Gaps = 34/200 (17%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLA SSAQ+LNEDVSQE+ P +I+    G S Q  ++ +  PP  G+   P
Sbjct: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDG--GDSEQFLDEERQGPPLGGQQSQP 58

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
               GN+  GP                          QGPP QGG Q QGPPPP GKPQG
Sbjct: 59  SAGDGNQDDGPQ-------------------------QGPPQQGGQQQQGPPPPQGKPQG 93

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
           PP QGG+ P   PP G+PQGPP QG     PR P G+PQGPP QGG+Q   PPPPPGKPQ
Sbjct: 94  PPQQGGHPP---PPQGRPQGPPQQGGH---PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQ 147

Query: 181 GPPPQGGKKPQGPPPPGKPQ 200
           GPPPQGG +PQGPP    PQ
Sbjct: 148 GPPPQGG-RPQGPPQGQSPQ 166



 Score =  158 bits (400), Expect = 6e-39
 Identities = 80/132 (60%), Positives = 87/132 (65%), Gaps = 12/132 (9%)

Query: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
           QGPP  G+ Q  P  GD ++      G  QGPP QGG Q QGPPPP GKPQGPP QGG  
Sbjct: 47  QGPPLGGQ-QSQPSAGDGNQDD----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101

Query: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
           P   PP G+PQGPP QG   R    P G+PQGPP QGG+Q   PPPPPGKPQGPPPQGG 
Sbjct: 102 P---PPQGRPQGPPQQGGHPRP---PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG- 154

Query: 250 KPQGPPPPGKPQ 261
           +PQGPP    PQ
Sbjct: 155 RPQGPPQGQSPQ 166



 Score =  145 bits (367), Expect = 4e-35
 Identities = 79/141 (56%), Positives = 87/141 (61%), Gaps = 26/141 (18%)

Query: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 250
           QGPP  G+ Q  P  GD ++      G  QGPP QGG Q QGPPPP GKPQGPP QGG+ 
Sbjct: 47  QGPPLGGQ-QSQPSAGDGNQDD----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101

Query: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310
              PPP G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP
Sbjct: 102 ---PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPP-----------PP 142

Query: 311 AGQPQGPPRPPQGGRPSRPPQ 331
            G+PQGP  PPQGGRP  PPQ
Sbjct: 143 PGKPQGP--PPQGGRPQGPPQ 161



 Score =  137 bits (345), Expect = 1e-32
 Identities = 81/158 (51%), Positives = 92/158 (58%), Gaps = 41/158 (25%)

Query: 139 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP-G 197
           QGPP  G +S+           P    GNQ  GP       QGPP QGG++ QGPPPP G
Sbjct: 47  QGPPLGGQQSQ-----------PSAGDGNQDDGPQ------QGPPQQGGQQQQGPPPPQG 89

Query: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--PP 255
           KPQGPP QG        P G+PQGPP QGG+    P PP G+PQGPP QGG++ QG  PP
Sbjct: 90  KPQGPPQQGGHP---PPPQGRPQGPPQQGGH----PRPPRGRPQGPPQQGGHQ-QGPPPP 141

Query: 256 PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
           PPGKPQGPP QG           G+PQGPPQ  G +PQ
Sbjct: 142 PPGKPQGPPPQG-----------GRPQGPPQ--GQSPQ 166



 Score =  108 bits (269), Expect = 9e-24
 Identities = 64/134 (47%), Positives = 74/134 (55%), Gaps = 28/134 (20%)

Query: 183 PPQGGKKPQ-----GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP-- 235
           PP GG++ Q     G    G  QGPP QG + +         QGPPP  G +PQGPP   
Sbjct: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQ---------QGPPPPQG-KPQGPPQQG 98

Query: 236 -----PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 290
                P G+PQGPP QGG+     PP G+PQGPP QGG +      PPGKPQGPP Q G 
Sbjct: 99  GHPPPPQGRPQGPPQQGGHP---RPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQ-GG 154

Query: 291 NPQGPPPPAGGNPQ 304
            PQG  PP G +PQ
Sbjct: 155 RPQG--PPQGQSPQ 166


>gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score =  192 bits (489), Expect = 3e-49
 Identities = 107/200 (53%), Positives = 122/200 (61%), Gaps = 34/200 (17%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLA SSAQ+L+EDVSQE+ P +I+    G S Q  ++ +  PP  G+   P
Sbjct: 1   MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDG--GDSEQFIDEERQGPPLGGQQSQP 58

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
               GN+  GP                          QGPP QGG Q QGPPPP GKPQG
Sbjct: 59  SAGDGNQNDGPQ-------------------------QGPPQQGGQQQQGPPPPQGKPQG 93

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
           PP QGG+ P   PP G+PQGPP QG     PR P G+PQGPP QGG+Q   PPPPPGKPQ
Sbjct: 94  PPQQGGHPP---PPQGRPQGPPQQGGH---PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQ 147

Query: 181 GPPPQGGKKPQGPPPPGKPQ 200
           GPPPQGG +PQGPP    PQ
Sbjct: 148 GPPPQGG-RPQGPPQGQSPQ 166



 Score =  159 bits (401), Expect = 4e-39
 Identities = 80/132 (60%), Positives = 88/132 (66%), Gaps = 12/132 (9%)

Query: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
           QGPP  G+ Q  P  GD +++     G  QGPP QGG Q QGPPPP GKPQGPP QGG  
Sbjct: 47  QGPPLGGQ-QSQPSAGDGNQND----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101

Query: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
           P   PP G+PQGPP QG   R    P G+PQGPP QGG+Q   PPPPPGKPQGPPPQGG 
Sbjct: 102 P---PPQGRPQGPPQQGGHPRP---PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG- 154

Query: 250 KPQGPPPPGKPQ 261
           +PQGPP    PQ
Sbjct: 155 RPQGPPQGQSPQ 166



 Score =  146 bits (368), Expect = 3e-35
 Identities = 79/141 (56%), Positives = 88/141 (62%), Gaps = 26/141 (18%)

Query: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 250
           QGPP  G+ Q  P  GD +++     G  QGPP QGG Q QGPPPP GKPQGPP QGG+ 
Sbjct: 47  QGPPLGGQ-QSQPSAGDGNQND----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101

Query: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310
              PPP G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP
Sbjct: 102 ---PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPP-----------PP 142

Query: 311 AGQPQGPPRPPQGGRPSRPPQ 331
            G+PQGP  PPQGGRP  PPQ
Sbjct: 143 PGKPQGP--PPQGGRPQGPPQ 161



 Score =  137 bits (344), Expect = 2e-32
 Identities = 81/158 (51%), Positives = 92/158 (58%), Gaps = 41/158 (25%)

Query: 139 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP-G 197
           QGPP  G +S+           P    GNQ  GP       QGPP QGG++ QGPPPP G
Sbjct: 47  QGPPLGGQQSQ-----------PSAGDGNQNDGPQ------QGPPQQGGQQQQGPPPPQG 89

Query: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--PP 255
           KPQGPP QG        P G+PQGPP QGG+    P PP G+PQGPP QGG++ QG  PP
Sbjct: 90  KPQGPPQQGGHP---PPPQGRPQGPPQQGGH----PRPPRGRPQGPPQQGGHQ-QGPPPP 141

Query: 256 PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
           PPGKPQGPP QG           G+PQGPPQ  G +PQ
Sbjct: 142 PPGKPQGPPPQG-----------GRPQGPPQ--GQSPQ 166



 Score =  107 bits (268), Expect = 1e-23
 Identities = 64/134 (47%), Positives = 74/134 (55%), Gaps = 28/134 (20%)

Query: 183 PPQGGKKPQ-----GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP-- 235
           PP GG++ Q     G    G  QGPP QG + +         QGPPP  G +PQGPP   
Sbjct: 49  PPLGGQQSQPSAGDGNQNDGPQQGPPQQGGQQQ---------QGPPPPQG-KPQGPPQQG 98

Query: 236 -----PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 290
                P G+PQGPP QGG+     PP G+PQGPP QGG +      PPGKPQGPP Q G 
Sbjct: 99  GHPPPPQGRPQGPPQQGGHP---RPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQ-GG 154

Query: 291 NPQGPPPPAGGNPQ 304
            PQG  PP G +PQ
Sbjct: 155 RPQG--PPQGQSPQ 166


>gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score =  192 bits (489), Expect = 3e-49
 Identities = 107/200 (53%), Positives = 122/200 (61%), Gaps = 34/200 (17%)

Query: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60
           MLLILLSVALLA SSAQ+L+EDVSQE+ P +I+    G S Q  ++ +  PP  G+   P
Sbjct: 1   MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDG--GDSEQFIDEERQGPPLGGQQSQP 58

Query: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
               GN+  GP                          QGPP QGG Q QGPPPP GKPQG
Sbjct: 59  SAGDGNQNDGPQ-------------------------QGPPQQGGQQQQGPPPPQGKPQG 93

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
           PP QGG+ P   PP G+PQGPP QG     PR P G+PQGPP QGG+Q   PPPPPGKPQ
Sbjct: 94  PPQQGGHPP---PPQGRPQGPPQQGGH---PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQ 147

Query: 181 GPPPQGGKKPQGPPPPGKPQ 200
           GPPPQGG +PQGPP    PQ
Sbjct: 148 GPPPQGG-RPQGPPQGQSPQ 166



 Score =  159 bits (401), Expect = 4e-39
 Identities = 80/132 (60%), Positives = 88/132 (66%), Gaps = 12/132 (9%)

Query: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
           QGPP  G+ Q  P  GD +++     G  QGPP QGG Q QGPPPP GKPQGPP QGG  
Sbjct: 47  QGPPLGGQ-QSQPSAGDGNQND----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101

Query: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
           P   PP G+PQGPP QG   R    P G+PQGPP QGG+Q   PPPPPGKPQGPPPQGG 
Sbjct: 102 P---PPQGRPQGPPQQGGHPRP---PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG- 154

Query: 250 KPQGPPPPGKPQ 261
           +PQGPP    PQ
Sbjct: 155 RPQGPPQGQSPQ 166



 Score =  146 bits (368), Expect = 3e-35
 Identities = 79/141 (56%), Positives = 88/141 (62%), Gaps = 26/141 (18%)

Query: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 250
           QGPP  G+ Q  P  GD +++     G  QGPP QGG Q QGPPPP GKPQGPP QGG+ 
Sbjct: 47  QGPPLGGQ-QSQPSAGDGNQND----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101

Query: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310
              PPP G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP
Sbjct: 102 ---PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPP-----------PP 142

Query: 311 AGQPQGPPRPPQGGRPSRPPQ 331
            G+PQGP  PPQGGRP  PPQ
Sbjct: 143 PGKPQGP--PPQGGRPQGPPQ 161



 Score =  137 bits (344), Expect = 2e-32
 Identities = 81/158 (51%), Positives = 92/158 (58%), Gaps = 41/158 (25%)

Query: 139 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP-G 197
           QGPP  G +S+           P    GNQ  GP       QGPP QGG++ QGPPPP G
Sbjct: 47  QGPPLGGQQSQ-----------PSAGDGNQNDGPQ------QGPPQQGGQQQQGPPPPQG 89

Query: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--PP 255
           KPQGPP QG        P G+PQGPP QGG+    P PP G+PQGPP QGG++ QG  PP
Sbjct: 90  KPQGPPQQGGHP---PPPQGRPQGPPQQGGH----PRPPRGRPQGPPQQGGHQ-QGPPPP 141

Query: 256 PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
           PPGKPQGPP QG           G+PQGPPQ  G +PQ
Sbjct: 142 PPGKPQGPPPQG-----------GRPQGPPQ--GQSPQ 166



 Score =  107 bits (268), Expect = 1e-23
 Identities = 64/134 (47%), Positives = 74/134 (55%), Gaps = 28/134 (20%)

Query: 183 PPQGGKKPQ-----GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP-- 235
           PP GG++ Q     G    G  QGPP QG + +         QGPPP  G +PQGPP   
Sbjct: 49  PPLGGQQSQPSAGDGNQNDGPQQGPPQQGGQQQ---------QGPPPPQG-KPQGPPQQG 98

Query: 236 -----PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 290
                P G+PQGPP QGG+     PP G+PQGPP QGG +      PPGKPQGPP Q G 
Sbjct: 99  GHPPPPQGRPQGPPQQGGHP---RPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQ-GG 154

Query: 291 NPQGPPPPAGGNPQ 304
            PQG  PP G +PQ
Sbjct: 155 RPQG--PPQGQSPQ 166


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score =  176 bits (447), Expect = 2e-44
 Identities = 132/315 (41%), Positives = 143/315 (45%), Gaps = 58/315 (18%)

Query: 39  PSPQGGNKPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97
           P PQG  +P GP    G PQGPP  QGG  PQG   P  PQGPP    + +    P G  
Sbjct: 620 PGPQGQFRPPGPQGQMG-PQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQ 678

Query: 98  QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG---KPQGPP-PQGDKSRSPRS 153
           + P P G   PQGPP P G      PQG   PQGPP P     PQGPP PQG     P+ 
Sbjct: 679 RHPGPHGPLGPQGPPGPQG---SSGPQGHMGPQGPPGPQGHIGPQGPPGPQG--HLGPQG 733

Query: 154 PPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP--------------QGPPPPG 197
           PPG    QGPP  G    QGPP P G   GP  QG + P              QGPP P 
Sbjct: 734 PPGTQGMQGPP--GPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPR 791

Query: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
           + QGP PQG        PP + +GP P GG    GP    G      PQ     QGPPP 
Sbjct: 792 ENQGPAPQG---MIMGHPPQEMRGPHPPGGLLGHGPQEMRG------PQEIRGMQGPPPQ 842

Query: 258 GKPQGPPAQGGSKSQSARSPPG--KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 315
           G   GPP       Q  R PPG    QGPPQ       GPPP  G      Q PP   PQ
Sbjct: 843 GSMLGPP-------QELRGPPGSQSQQGPPQ----GSLGPPPQGG-----MQGPPG--PQ 884

Query: 316 GPPRPPQGGRPSRPP 330
           G   P +G  PS+ P
Sbjct: 885 GQQNPARGPHPSQGP 899



 Score =  162 bits (410), Expect = 4e-40
 Identities = 138/341 (40%), Positives = 149/341 (43%), Gaps = 73/341 (21%)

Query: 36  PQG----PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPP-PQGDKS 87
           PQG    P P G   PQGPP P G      PQG   PQGPP P     PQGPP PQG   
Sbjct: 674 PQGMQRHPGPHGPLGPQGPPGPQG---SSGPQGHMGPQGPPGPQGHIGPQGPPGPQG--H 728

Query: 88  RSPRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP--------------QG 131
             P+ PPG    QGPP  G    QGPP P G   GP  QG   P              QG
Sbjct: 729 LGPQGPPGTQGMQGPP--GPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG 786

Query: 132 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191
           PP P + QGP PQG        PP + +GP P GG    GP    G      PQ  +  Q
Sbjct: 787 PPGPRENQGPAPQG---MIMGHPPQEMRGPHPPGGLLGHGPQEMRG------PQEIRGMQ 837

Query: 192 GPPPPGKPQGPP-----PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246
           GPPP G   GPP     P G  S+S Q PP    GPPPQGG   QGPP P G  Q  P +
Sbjct: 838 GPPPQGSMLGPPQELRGPPG--SQSQQGPPQGSLGPPPQGG--MQGPPGPQG--QQNPAR 891

Query: 247 GGNKPQGPPP------PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 300
           G +  QGP P      P    GP A    + QS   PP  P G  QQ     QG  PP  
Sbjct: 892 GPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIP-GLGQQ---GAQGRIPPL- 946

Query: 301 GNPQQPQAPPAGQPQGPP----------RPPQGGRPSRPPQ 331
            NP Q   P  G  +GPP          R  Q G P   P+
Sbjct: 947 -NPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPE 986



 Score =  139 bits (349), Expect = 5e-33
 Identities = 145/434 (33%), Positives = 166/434 (38%), Gaps = 151/434 (34%)

Query: 36   PQGPS-PQGGNKPQGPPPPPGK--PQGPP-PQGGNKPQGPPPPGKPQGPP-PQGDKSRSP 90
            PQG S PQG   PQGPP P G   PQGPP PQG   PQGPP     QGPP P+G   + P
Sbjct: 695  PQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRG--MQGP 752

Query: 91   RSPPGKPQGPPPQGGNQP--QGP-----------PPPPGKPQGPPPQG---GNRPQ---G 131
              P G   GP  QG   P  QGP           PP P + QGP PQG   G+ PQ   G
Sbjct: 753  PHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRG 812

Query: 132  PPPPGK-----------------PQGPPPQGDKSRSP---RSPPGK------PQG---PP 162
            P PPG                   QGPPPQG     P   R PPG       PQG   PP
Sbjct: 813  PHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPP 872

Query: 163  PQGGNQPQGPPPPPGKP---QGPPPQGGKKP----------QGPPPP----GKPQGPPPQ 205
            PQGG Q  GPP P G+    +GP P  G  P           GP  P    G+  GPPP 
Sbjct: 873  PQGGMQ--GPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL 930

Query: 206  ----GDKSRSSQSPPGKP-QGPPPQGGNQPQGPP-----------------PPPGKPQGP 243
                G +    + PP  P QGP P  G+  +GPP                 P  G  +GP
Sbjct: 931  IPGLGQQGAQGRIPPLNPGQGPGPNKGDS-RGPPNHHMGPMSERRHEQSGGPEHGPERGP 989

Query: 244  ---------PP----------------------------------QGGNKPQ-------G 253
                     PP                                  +GG  PQ       G
Sbjct: 990  FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGG 1049

Query: 254  PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ----AP 309
            P PP  P       G    +AR PPG  +G    +   P+ P  P     ++      AP
Sbjct: 1050 PGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP 1109

Query: 310  PAGQPQGPPRPPQG 323
            P  + + PPR   G
Sbjct: 1110 PRHEGRAPPRGRDG 1123



 Score =  132 bits (331), Expect = 6e-31
 Identities = 120/317 (37%), Positives = 130/317 (41%), Gaps = 107/317 (33%)

Query: 111 PPPPPGKPQ-GPPPQGGNRPQGPPPPGKPQ--------------GPP-PQGDKSRSPRSP 154
           PPP  G P  GP P  G  P    P G  Q              GPP PQG     P  P
Sbjct: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG--QFRPPGP 631

Query: 155 PGK--PQGPP-PQGGNQPQ---GPPPPPGKPQGPP-------PQGGKKPQGPPPPGKPQG 201
            G+  PQGPP  QGG  PQ   GP  P G PQG P       PQG ++  GP  P  PQG
Sbjct: 632 QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQG 691

Query: 202 PP-PQGDKSRSSQSPPGK--PQGPP-PQGGNQPQGPPPPPGK--PQGPPPQGGNKPQGPP 255
           PP PQG     S  P G   PQGPP PQG   PQGPP P G   PQGPP  G    QGPP
Sbjct: 692 PPGPQG-----SSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPP--GTQGMQGPP 744

Query: 256 PPGKPQGPP----AQGGSKSQSARSPPGK-------------PQGPPQQEGNNPQ----- 293
            P   QGPP     QGG  SQ  + P  +             P GP + +G  PQ     
Sbjct: 745 GPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMG 804

Query: 294 -------GPPPPAG----------------------------GNPQQPQAPPAGQ-PQGP 317
                  GP PP G                            G PQ+ + PP  Q  QGP
Sbjct: 805 HPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP 864

Query: 318 PR-----PPQGGRPSRP 329
           P+     PPQGG    P
Sbjct: 865 PQGSLGPPPQGGMQGPP 881



 Score = 98.2 bits (243), Expect = 9e-21
 Identities = 70/169 (41%), Positives = 76/169 (44%), Gaps = 17/169 (10%)

Query: 172 PPPPPGKPQ-GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQP 230
           PPP  G P  GP P  G+ P    P G  Q  P Q      +Q  P     P PQG  +P
Sbjct: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGP-----PGPQGQFRP 628

Query: 231 QGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 289
            GP    G PQGPP  QGG  PQG   P  PQGPP QG  + Q    P G  + P     
Sbjct: 629 PGPQGQMG-PQGPPLHQGGGGPQGFMGPQGPQGPP-QGLPRPQDMHGPQGMQRHPGPHGP 686

Query: 290 NNPQGPPPPAGGNPQQ----PQAPPAGQ----PQGPPRPPQGGRPSRPP 330
             PQGPP P G +  Q    PQ PP  Q    PQGPP P     P  PP
Sbjct: 687 LGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPP 735



 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 109/416 (26%), Positives = 144/416 (34%), Gaps = 125/416 (30%)

Query: 25   QEESPSLIAGNPQGPSPQGGNKPQGPPP--------------PPGKP-QGPPPQGGNKPQ 69
            Q++   L+   P+ P  Q G +  GPPP              PP  P QGP P   NK  
Sbjct: 903  QQQKTPLLGDGPRAPFNQEG-QSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGP---NKGD 958

Query: 70   GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP----PPPGKPQ------ 119
               PP    GP  +    +S   P   P+  P +GG   +GPP    P P  P       
Sbjct: 959  SRGPPNHHMGPMSERRHEQS-GGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017

Query: 120  -------------------GPPPQGGN-RPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKP 158
                               GP PQ    R  GP PP  P      +GD   + R PPG  
Sbjct: 1018 DFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAW 1077

Query: 159  QGPPPQGGNQPQGPPPPPGK-------PQGPPP--QGGKKPQGPP--PPGKPQGPPPQGD 207
            +G  P     P+ P  P  +        +G PP  +G   P+G    P  +  GP    D
Sbjct: 1078 EGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFD 1137

Query: 208  KSRSS---QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-----PPPPG- 258
             S  +   +   G+ +G  P+GG +   P P     + P  +GG KP        P PG 
Sbjct: 1138 ASEEAARGRDLRGRGRG-TPRGGRKGLLPTP----DEFPRFEGGRKPDSWDGNREPGPGH 1192

Query: 259  -------KPQGPPAQGGSKSQSARS-----------PPGK-----------------PQG 283
                   +P  PP  G S +   RS           PP K                 P G
Sbjct: 1193 EHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGG 1252

Query: 284  PPQQEGNNPQGPPPPAGGNPQQPQA--------------PPAGQPQGPPRPPQGGR 325
            P +  G   +G P PA   P+  ++               P G P G   P +GGR
Sbjct: 1253 PSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGR 1308



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 72/301 (23%), Positives = 98/301 (32%), Gaps = 82/301 (27%)

Query: 38   GPSPQGGNKPQGPPPPP--------------GKPQGPPPQG-GNKPQGPPPPGKPQGPPP 82
            GP PQ     +G P PP              G  +GPP    G +P     P  P+ P  
Sbjct: 1037 GPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRF 1096

Query: 83   QGDKSRSPR--SPPGKPQGPPPQGGNQPQGPPP----------------------PPGKP 118
            +G +  S R  +PP      PP+G +   GP                          G P
Sbjct: 1097 RGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTP 1156

Query: 119  QG------PPP------QGGNRPQG-----PPPPG--------KPQGPPPQGDKSRSPRS 153
            +G      P P      +GG +P        P PG        +P  PP  G       S
Sbjct: 1157 RGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDG------HS 1210

Query: 154  PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG--------PPPQ 205
            P  + +    QG +    PP       GP     ++ + P  P + +G        P  +
Sbjct: 1211 PASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQR 1270

Query: 206  GDKSRSSQSPPGKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 261
              KS  S S  G+         P GG    G P   G+      +G N   GPP  G  +
Sbjct: 1271 VPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASR 1330

Query: 262  G 262
            G
Sbjct: 1331 G 1331


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  150 bits (380), Expect = 1e-36
 Identities = 120/327 (36%), Positives = 124/327 (37%), Gaps = 32/327 (9%)

Query: 36   PQGPSPQGGNKPQGPPPP-PGKPQGPPP-------------QGGNKPQGPPPPGKPQGPP 81
            PQ P  QG      PPPP PG    PPP              G   P  PP PG    PP
Sbjct: 897  PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956

Query: 82   PQGDKSRSPRSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNRPQGPPPPG 136
            P    +  P  PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG
Sbjct: 957  PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016

Query: 137  KPQGPPPQGDKSRSPRSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGKKPQ 191
                PPP    +  P  PP    G P  PP  G   P  PP P  G P  PP  G   P 
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076

Query: 192  GPPPPGKPQGPPPQGDKSRSSQSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQ 246
             PP PG    PPP    +     PP    G P  PP  G   P  PP P  G P  PP  
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136

Query: 247  GGNKPQGPPPP--GKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGNP 303
            G   P  PP P  G P  PP  G         P  G P  PP      P  PP P  G P
Sbjct: 1137 GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIP 1196

Query: 304  QQPQAPPAGQPQGPPRPPQGGRPSRPP 330
              P  P AG P  PP P  G  P+  P
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAP 1223



 Score =  147 bits (370), Expect = 2e-35
 Identities = 117/316 (37%), Positives = 120/316 (37%), Gaps = 33/316 (10%)

Query: 36   PQGPSPQGGNKPQGPPPPPGKPQGPPPQ--GGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG    PPP   G   P  PP PG    PPP    +  P  P
Sbjct: 933  PLPPLPGAGIPP--PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP 990

Query: 94   PGKPQGPPPQGGNQPQGPPPPP-----GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKS 148
            P    G PP       G PPPP     G P  PP  G   P  PP PG    PPP    +
Sbjct: 991  PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050

Query: 149  RSPRSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
              P  PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG    PP
Sbjct: 1051 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110

Query: 204  PQGDKSRSSQSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPG 258
            P    +     PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG 1170

Query: 259  K--PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP-- 314
               P  PP  G           G P  PP      P  PP P  G P  P  P  G P  
Sbjct: 1171 AGIPPPPPLPG----------VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPA 1220

Query: 315  QGPPRPPQGGRPSRPP 330
              PP PP G     PP
Sbjct: 1221 PAPPLPPPGTGIPPPP 1236



 Score =  139 bits (351), Expect = 3e-33
 Identities = 114/314 (36%), Positives = 118/314 (37%), Gaps = 29/314 (9%)

Query: 45   NKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGK----------PQGPPPQGDKSRSPRSP 93
            N P  PP P  +     P  G  P  PPP PG           PQ PP QG +   P  P
Sbjct: 854  NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913

Query: 94   P----GKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKS 148
            P    G P  PP P  G  P  P P  G P  PP  G   P  PP PG     PP    +
Sbjct: 914  PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA 973

Query: 149  RSPRSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
              P  PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG    PP
Sbjct: 974  GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1033

Query: 204  PQGDKSRSSQSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPG 258
            P    +     PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1093

Query: 259  K--PQGPPAQG-GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 315
               P  PP  G G          G P  PP      P  PP P  G P  P  P  G P 
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153

Query: 316  GPPRPPQGGRPSRP 329
             PP P  G  P  P
Sbjct: 1154 PPPLPGAGIPPPPP 1167



 Score =  138 bits (347), Expect = 8e-33
 Identities = 114/315 (36%), Positives = 118/315 (37%), Gaps = 39/315 (12%)

Query: 33   AGNPQGPSPQGGNKPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            AG P  P   G   P  PP P  G P  PP  G   P  PP PG    PPP    +  P 
Sbjct: 962  AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1021

Query: 92   SPPGKPQGPPPQGGNQPQGPPPPP-----GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD 146
             PP    G PP       G PPPP     G P  PP  G   P  PP PG    PPP   
Sbjct: 1022 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--- 1078

Query: 147  KSRSPRSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205
                P    G P  PP  G   P  PP P  G P  PP  G   P  PP PG    PPP 
Sbjct: 1079 ----PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134

Query: 206  GDKSRSSQSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGK- 259
               +     PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG  
Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194

Query: 260  -PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP----PPPAGGNPQQPQAPPAGQP 314
             P  PP  G           G P  PP      P  P    PPP  G P  P  P +   
Sbjct: 1195 IPPPPPLPGA----------GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVS--- 1241

Query: 315  QGPPRPPQGGRPSRP 329
             GPP  PQ G  + P
Sbjct: 1242 -GPPLLPQVGSSTLP 1255



 Score =  121 bits (304), Expect = 8e-28
 Identities = 110/340 (32%), Positives = 117/340 (34%), Gaps = 59/340 (17%)

Query: 47   PQGPPPPPGKPQGP-------------------------PPQGGNKPQGPPPP------- 74
            P  PP PPG   GP                         P Q  ++P  PPPP       
Sbjct: 764  PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQP--PPPPSLLWSAG 821

Query: 75   -GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133
             G+P   PP    +    S             N P  PP P  +     P  G  P  PP
Sbjct: 822  QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPP 881

Query: 134  P-PGK----------PQGPPPQGDKSRSPRSPP----GKPQGPP-PQGGNQPQGPPPPPG 177
            P PG           PQ PP QG +   P  PP    G P  PP P  G  P  P P  G
Sbjct: 882  PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAG 941

Query: 178  KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP----GKPQGPPPQGGNQPQGP 233
             P  PP  G   P  PP PG     PP    +     PP    G P  PP  G   P  P
Sbjct: 942  IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001

Query: 234  P-PPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGSKSQSARSP-PGKPQGPPQQEG 289
            P P  G P  PP  G   P  PP PG   P  PP  G         P  G P  PP    
Sbjct: 1002 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1061

Query: 290  NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
              P  PP P  G P  P  P AG P  PP P  G  P  P
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101



 Score =  121 bits (303), Expect = 1e-27
 Identities = 100/274 (36%), Positives = 109/274 (39%), Gaps = 27/274 (9%)

Query: 36   PQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93
            P  P P  G  P  PPP PG   P  PP  G   P  PP PG    PPP    +  P  P
Sbjct: 1021 PPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078

Query: 94   P----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKS 148
            P    G P  PP  G   P  PP P  G P  PP  G   P  PP PG    PPP    +
Sbjct: 1079 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1138

Query: 149  RSPRSPP----GKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
              P  PP    G P  PP  G   P  PP P  G P  PP  G   P  PP PG    PP
Sbjct: 1139 GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP 1198

Query: 204  PQGDKSRSSQSPP----GKPQGPPPQGGNQPQGPPPPPGKP-QGPP--PQGGNKPQGPP- 255
            P    +     PP    G P  P P       G PPPP  P  GPP  PQ G+     P 
Sbjct: 1199 PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258

Query: 256  -----PPGKPQGPPAQGGSKSQSARSPPGKPQGP 284
                 PP  P G    G ++ + +R  P +P  P
Sbjct: 1259 VCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292



 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 92/294 (31%), Positives = 98/294 (33%), Gaps = 69/294 (23%)

Query: 89   SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-------------------------PP 123
            SP    G    PP  G   P  PP PPG   GP                         P 
Sbjct: 747  SPTEEGGVLTLPPVDG--LPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804

Query: 124  QGGNRPQGPPPP--------GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
            Q  ++P  PPPP        G+P   PP    +    S             N P  PP P
Sbjct: 805  QSISQP--PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862

Query: 176  PGKPQGPPPQGGKKPQGPPP-PGK----------PQGPPPQGDKSRSSQSPP----GKPQ 220
              +     P  G  P  PPP PG           PQ PP QG +      PP    G P 
Sbjct: 863  CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922

Query: 221  GPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGSKSQSARSP 277
             PP P  G  P  P P  G P  PP  G   P  PP PG   P  PP  G          
Sbjct: 923  PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA--------- 973

Query: 278  PGKPQGPPQQEGNNPQGPPPPAGGN--PQQPQAPPAGQPQGPPRPPQGGRPSRP 329
             G P  PP      P  PPPP  G   P  P  P AG P  PP P  G  P  P
Sbjct: 974  -GIPPPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 65/247 (26%), Positives = 68/247 (27%), Gaps = 87/247 (35%)

Query: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPP----------------------QGD 207
           Q  P   G     PP  G   + P PPG   GP                        Q  
Sbjct: 745 QTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804

Query: 208 KSRSSQSPP---------GKPQGPPPQG-------------------------------- 226
           +S S   PP         G+P   PP                                  
Sbjct: 805 QSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCT 864

Query: 227 ---------GNQPQGPPPPPGK----------PQGPPPQGGNKPQGPPPP----GKPQGP 263
                    G  P  PPP PG           PQ PP QG      PPPP    G P  P
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP 924

Query: 264 PAQGGSKSQSARSP-PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322
           P  G         P  G P  PP      P  PP P  G P  P  P AG P  PP P  
Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA 984

Query: 323 GGRPSRP 329
           G  P  P
Sbjct: 985 GIPPPPP 991



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 61/241 (25%), Positives = 80/241 (33%), Gaps = 32/241 (13%)

Query: 103 QGGNQPQGPP----PPPGKPQGPP-----PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS 153
           QG  +P  PP    P PG   G       P GG        PG P         S  P S
Sbjct: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGG----AGEAPGSPDTEQALSALSDLPES 282

Query: 154 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ-GGKKPQGPPPPGKPQGPPPQGDKSRSS 212
              +P+        +PQ PP P G P    P     +P     P     P P+      +
Sbjct: 283 LAAEPR--------EPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEA 334

Query: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNKPQ--GPPPPGKPQGPPAQGG 268
              P +  G   + G +      P G P  +  P  G + PQ  G  P  + QGP A   
Sbjct: 335 AGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDA--- 391

Query: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
               +A S PG P    +     P   P       +Q  +P     Q P + P+  R   
Sbjct: 392 ---PAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPE 448

Query: 329 P 329
           P
Sbjct: 449 P 449



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 58/224 (25%), Positives = 76/224 (33%), Gaps = 31/224 (13%)

Query: 42  QGGNKPQGPP----PPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
           QG  +P  PP    P PG   G       P GG   + P  P   Q      D   S  +
Sbjct: 227 QGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGG-AGEAPGSPDTEQALSALSDLPESLAA 285

Query: 93  PPGKPQGPPPQGG-------NQPQGPPPPPGKPQG---PPPQGGNRPQGPPPPGKPQG-P 141
            P +PQ PP  GG       + P   P     P     P P+ G   +    P +  G  
Sbjct: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345

Query: 142 PPQGDKSRSPRSPPGKP--QGPPPQGGNQPQG-PPPPPGKPQGP-PPQGGKKPQGPPPPG 197
             +G++     +P G P  +  P  G + PQ     P  + QGP  P     P  P P  
Sbjct: 346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQ 405

Query: 198 KPQGPPPQ------GDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235
           +   P P          +R   SP   P   P Q     + P P
Sbjct: 406 RCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  150 bits (379), Expect = 2e-36
 Identities = 119/327 (36%), Positives = 135/327 (41%), Gaps = 46/327 (14%)

Query: 33   AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDK-SRSP 90
            AG    P P G   P GPP P GK  G  P+G   P G P    P GPP P G+K S   
Sbjct: 880  AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939

Query: 91   RSPPGKPQGPPPQGGNQPQGPPPPPGK------PQGPPPQGGNRPQGPPPPGKPQGPPPQ 144
              P G P  P PQG    +G    PG+      P  P P G    QGP      +GPP  
Sbjct: 940  DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP-- 997

Query: 145  GDKSRSPRSPPGKPQGPPPQGGNQ----PQGPPPPPGKPQGPPPQGGKKPQGPP-PPGKP 199
                  P  PPG   GPP + G +     +G P   G P     +G   P GPP  PG P
Sbjct: 998  -----GPMGPPGLA-GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP 1051

Query: 200  QGPPPQGDKSRSS---QSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQG-----GNK 250
              P P G   +S    ++ P  P GP  P G   P GP  P G       QG     G++
Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111

Query: 251  P----QGPP-PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN----PQGPPPPAG- 300
                 QGPP PPG P      G S     R PPG   G P ++G N    P GPP P G 
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGS-AGAPGKDGLNGLPGPIGPPGPRGR 1170

Query: 301  ---GNPQQPQAPPAGQPQGPPRPPQGG 324
                 P  P  PP   P GPP PP  G
Sbjct: 1171 TGDAGPVGPPGPPG--PPGPPGPPSAG 1195



 Score =  140 bits (352), Expect = 2e-33
 Identities = 119/360 (33%), Positives = 143/360 (39%), Gaps = 70/360 (19%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85
            +  P    G+P     +G   P GPP P G    P  +G + P GP  P   +G P  GD
Sbjct: 747  DAGPKGADGSPGKDGVRGLTGPIGPPGPAG---APGDKGESGPSGPAGPTGARGAP--GD 801

Query: 86   KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP--- 142
            +        G+P  P P G   P G    PG    P   G     GPP P  P GPP   
Sbjct: 802  R--------GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI 853

Query: 143  -----PQGDKSRSPRSPPGKP--------QGPP-PQGGNQPQGPPPPPGKPQGPPPQGGK 188
                 P    +R    PPG           GPP P G   P GPP P GK  G  P+G  
Sbjct: 854  GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGET 913

Query: 189  KPQGPPPPGKPQGPP-PQGDK-SRSSQSPPGKPQGPPPQG-----------GNQPQ---- 231
             P G P    P GPP P G+K S  +  P G P  P PQG           G + +    
Sbjct: 914  GPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFP 973

Query: 232  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN- 290
            G P P G+P    P G +  +GPP    P GPP   G   +S R      +G P ++G+ 
Sbjct: 974  GLPGPSGEPGKQGPSGASGERGPP---GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSP 1030

Query: 291  ---NPQGPPPPAG--GNPQQPQAP----PAGQ--------PQGPPRP--PQGGRPSRPPQ 331
                 +G   PAG  G P  P AP    PAG+        P GP  P  P G R    PQ
Sbjct: 1031 GAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQ 1090



 Score =  139 bits (350), Expect = 3e-33
 Identities = 122/391 (31%), Positives = 147/391 (37%), Gaps = 98/391 (25%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP----------PPGKP- 77
           P  + G P  P PQG    QGPP  PG+P    P G   P GPP           PG+P 
Sbjct: 186 PRGLPGPPGAPGPQGF---QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242

Query: 78  -QGPP-PQGDKS----------------------------RSPRSPPGKP--QGPPPQGG 105
            +GPP PQG +                               P+  PG P   G P Q G
Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302

Query: 106 NQPQGPPPPPGKPQGPPPQG--GNR----PQGPPPPGKPQGPP-------------PQGD 146
             P+G P   G+P  P P G  GN       GPP P  P GPP             PQG 
Sbjct: 303 --PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGP 360

Query: 147 K-SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP-----QGPP-------------PQGG 187
           + S  P+   G+P  P P G   P G P   G+P      G P             P G 
Sbjct: 361 RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGP 420

Query: 188 KKPQGPPPP----GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ----PQGPPPPPGK 239
           + P GPP P    G+P  P  +GD     +  P   QGPP   G +     +G P P G 
Sbjct: 421 QGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480

Query: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 299
           P  P  +GG   +G P      GP    G +       P  P+G P + G   +   P A
Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG---PAGPKGSPGEAGRPGEAGLPGA 537

Query: 300 GGNPQQPQAPPAGQPQGPPRPP-QGGRPSRP 329
            G    P +P      GPP P  Q GRP  P
Sbjct: 538 KGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP 568



 Score =  138 bits (347), Expect = 8e-33
 Identities = 110/345 (31%), Positives = 135/345 (39%), Gaps = 51/345 (14%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-----PPQ 83
           P+   GN       G   P GP  PPG P     +G   PQGP     PQG      PP 
Sbjct: 318 PAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPG 377

Query: 84  GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP----GKPQ 139
              +  P   PG    P  +G N   G    PG P    P G   P GPP P    G+P 
Sbjct: 378 PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPG 437

Query: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQ----------PQGPPPPPGKPQGPP------ 183
            P  +GD        P   QGPP   G +          P G P PPG+  GP       
Sbjct: 438 APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG 497

Query: 184 ------PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP-----PGKPQGPPPQGGNQPQG 232
                 P+G    +G P P  P+G P +  +   +  P      G P  P P G   P G
Sbjct: 498 ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557

Query: 233 PPPPPGKPQGPPPQGGNKPQ----GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288
           P    G+P GPP   G + Q    G P P    G P + G +      PPG   GP  ++
Sbjct: 558 PAGQDGRP-GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER--GVPGPPG-AVGPAGKD 613

Query: 289 GN-NPQGPPPPAGGNPQQPQAPPAGQP-----QGPPRPP-QGGRP 326
           G    QGPP PAG   ++ +  PAG P      GP  PP + G+P
Sbjct: 614 GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658



 Score =  133 bits (334), Expect = 3e-31
 Identities = 120/370 (32%), Positives = 139/370 (37%), Gaps = 83/370 (22%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ----------GGNKPQGPPPPGKPQG-- 79
           I G P  P P G   P GPP PPG      PQ          GG    GP  P  P+G  
Sbjct: 134 IPGQPGLPGPPG---PPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLP 190

Query: 80  PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-----PQGPPPQGGNRPQGPPP 134
            PP     +  + PPG+P  P   G   P+GPP PPGK       G P + G R  GPP 
Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGER--GPPG 248

Query: 135 PGKPQGPP-------------------PQGDKS-RSPRSPPGKP--QGPPPQGGNQPQGP 172
           P   +G P                    +GD     P+  PG P   G P Q G  P+G 
Sbjct: 249 PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG--PRGL 306

Query: 173 PPPPGKPQGPPPQGGK------KPQGPPPPGKPQGPP-------------PQGDK-SRSS 212
           P   G+P  P P G +         GPP P  P GPP             PQG + S   
Sbjct: 307 PGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP 366

Query: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKP------------QGPPPQGGNKPQGPPPPGKP 260
           Q   G+P  P P G   P G P   G+P              P   G   P GP  PG P
Sbjct: 367 QGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426

Query: 261 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320
            GP    G             +G P   G   QGPP PAG   ++      G P G P P
Sbjct: 427 PGPKGNSGEPGAPGSKGDTGAKGEPGPVG--VQGPPGPAGEEGKRGARGEPG-PTGLPGP 483

Query: 321 P--QGGRPSR 328
           P  +GG  SR
Sbjct: 484 PGERGGPGSR 493



 Score =  130 bits (327), Expect = 2e-30
 Identities = 113/360 (31%), Positives = 125/360 (34%), Gaps = 72/360 (20%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP------- 81
            PS   G    P  +G   P GP  P G    P   G     G P     QG P       
Sbjct: 672  PSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG 731

Query: 82   ---------PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
                     P+GD  R    P G    P   G     GP  PPG    P  +G + P GP
Sbjct: 732  ERGAAGLPGPKGD--RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGP 789

Query: 133  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192
              P   +G P  GD+        G+P  P P G   P G    PG    P   G K   G
Sbjct: 790  AGPTGARGAP--GDR--------GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG 839

Query: 193  PPPPGKPQGPP--------PQGDKSRSSQSPPGKP--------QGPP-PQGGNQPQGPPP 235
            PP P  P GPP        P    +R S  PPG           GPP P G   P GPP 
Sbjct: 840  PPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899

Query: 236  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK-SQSARSPPGKPQGP---------- 284
            P GK  G  P+G   P G P    P GPP   G K S  A  P G P  P          
Sbjct: 900  PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959

Query: 285  ----PQQEGN-------NPQGPPPPAGGNPQQPQAPPAGQPQGPP----RPPQGGRPSRP 329
                P Q G         P G P   G +    +  P G P GPP     P + GR   P
Sbjct: 960  VVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG-PMGPPGLAGPPGESGREGAP 1018



 Score =  129 bits (324), Expect = 4e-30
 Identities = 128/390 (32%), Positives = 147/390 (37%), Gaps = 101/390 (25%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQG----PPP------PGKP---- 77
           + G+P  P P G   P GP    G+P  P P G     G    P P      PGK     
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERG 599

Query: 78  -QGPP----PQG-DKSRSPRSPPGKPQGPPPQGGNQ-------------PQGPPPPPGKP 118
             GPP    P G D     + PPG P GP  + G Q             P GPP   GKP
Sbjct: 600 VPGPPGAVGPAGKDGEAGAQGPPG-PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658

Query: 119 --QGPP-------PQGGNRPQGPPPPGKPQGPP-PQGDKSRS-------PRSPPGKPQGP 161
             QG P       P G    +G P     QGPP P G +  +        +   G P  P
Sbjct: 659 GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP 718

Query: 162 PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP----PPGK--------PQGPP----PQ 205
             QG    QG P   G    P P+G +   GP      PGK        P GPP      
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778

Query: 206 GDKSRSSQSPPGKPQG----------PPPQGGNQPQGPPPPPGKP--QGPPPQGGNK--- 250
           GDK  S  S P  P G          P P G     GPP   G+P  +G P   G K   
Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA 838

Query: 251 -PQGPPPPGKPQGP----PAQGGSKSQSARSPPGKP--------QGPPQQEGN-NPQGPP 296
            P GP  P  P GP     A G   ++ +  PPG           GPP   GN  P GPP
Sbjct: 839 GPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP 898

Query: 297 PPA---GGNPQQPQAPPAGQP--QGPPRPP 321
            PA   GG   + +  PAG+P   GPP PP
Sbjct: 899 GPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928



 Score =  126 bits (317), Expect = 2e-29
 Identities = 115/337 (34%), Positives = 129/337 (38%), Gaps = 65/337 (19%)

Query: 36  PQGPSPQGGNKPQ----GPPPPPGKPQGPPPQGGN-KPQ-----GPPPPGKPQGPPPQGD 85
           P GP  + G   Q    GPP PPG P GPP  GGN  PQ          G    P P G 
Sbjct: 125 PAGPPGRDGIPGQPGLPGPPGPPGPP-GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGP 183

Query: 86  KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP----------PP 135
               PR  PG P  P PQG    QGPP  PG+P    P G   P GPP           P
Sbjct: 184 SG--PRGLPGPPGAPGPQGF---QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKP 238

Query: 136 GKP--QGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQ-------------PQGPPPPPGKP 179
           G+P  +GPP PQG      R  PG   G P   G++             P GP   PG P
Sbjct: 239 GRPGERGPPGPQG-----ARGLPGTA-GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSP 292

Query: 180 --QGPPPQGGKKPQG-PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
              G P Q G  P+G P   G+P  P P G +     +    P GP         GP  P
Sbjct: 293 GENGAPGQMG--PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT--------GPAGP 342

Query: 237 PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 296
           PG P     +G   PQGP     PQG   + G    +  + P    G   Q G       
Sbjct: 343 PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402

Query: 297 PPAGGNPQQPQAPPAGQPQGPPRPP----QGGRPSRP 329
           P   G P  P A     PQGP  PP      G P  P
Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP 439



 Score =  120 bits (302), Expect = 1e-27
 Identities = 117/347 (33%), Positives = 134/347 (38%), Gaps = 67/347 (19%)

Query: 33  AGNPQGPS-PQGGNKPQGPPPPPG-----KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
           A  P GP+ P G    QGP   PG      P GPP + G KP     PG    P P G  
Sbjct: 618 AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG-KPGEQGVPGDLGAPGPSG-- 674

Query: 87  SRSPRSPPGKP--QGPP----PQGGNQP---QGPPPPPGKPQGPPPQGGNRPQGPPPPGK 137
           +R  R  PG+   QGPP    P+G N      G     G P  P  QG    QG P    
Sbjct: 675 ARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERG 734

Query: 138 PQG-PPPQGDKSRS-PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP- 194
             G P P+GD+  + P+   G P     +G   P GPP P G P      G   P GP  
Sbjct: 735 AAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794

Query: 195 ---PPGK-----PQGP-----PPQGDKSRSSQSPPGKP-----QGPPPQGGNQPQGPPPP 236
               PG      P GP     PP  D    ++  PG        GPP   G  P GPP P
Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG--PAGPPGP 852

Query: 237 PGKPQGPPPQGGNKPQGPP-------------PPGK-----PQGPPAQGGSKSQSARSPP 278
            G    P  +G     GPP             PPG      P GPP   G   +  + P 
Sbjct: 853 IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG--KEGGKGPR 910

Query: 279 GK--PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 323
           G+  P G P + G  P GPP PAG         PAG P  P   PQG
Sbjct: 911 GETGPAGRPGEVG--PPGPPGPAGEKGSPGADGPAGAPGTP--GPQG 953



 Score =  117 bits (293), Expect = 1e-26
 Identities = 103/339 (30%), Positives = 130/339 (38%), Gaps = 46/339 (13%)

Query: 27  ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP-----QGPP-------------PQGGNKP 68
           E P  + G P  P P G   P G P   G+P      G P             P G   P
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423

Query: 69  QGPPPP----GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ----PQGPPPPPGKPQG 120
            GPP P    G+P  P  +GD        P   QGPP   G +     +G P P G P  
Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP----P 176
           P  +GG   +G P      GP     +  SP   P  P+G P + G   +   P      
Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPG--PAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 177 GKPQGPPPQGGKKPQGPP-PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ-PQGPP 234
           G P  P P G   P GP    G+P  P P G + ++       P+G   + G    +G P
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601

Query: 235 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPA-QGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
            PPG        G    QGPP P  P G    QG + S   +  PG P GPP + G   +
Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG-PAGPPGEAGKPGE 660

Query: 294 -------GPPPPAGGNPQQPQAPPAGQPQGPPRP--PQG 323
                  G P P+G   ++   P     QGPP P  P+G
Sbjct: 661 QGVPGDLGAPGPSGARGER-GFPGERGVQGPPGPAGPRG 698



 Score =  112 bits (279), Expect = 6e-25
 Identities = 114/349 (32%), Positives = 134/349 (38%), Gaps = 90/349 (25%)

Query: 43  GGNKPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 100
           G   P+G   P  P   + P  Q     +GP     P+GP       R P  PPG+  G 
Sbjct: 83  GAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGP-------RGPAGPPGR-DGI 134

Query: 101 PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 160
           P Q G    GPP PPG P GPP  GGN          PQ      +KS    S PG P G
Sbjct: 135 PGQPGLP--GPPGPPGPP-GPPGLGGNFA--------PQLSYGYDEKSTGGISVPG-PMG 182

Query: 161 PP-PQGGNQPQGPPPPPGKPQGPP----------PQGGKKPQGPP----------PPGKP 199
           P  P+G   P G P P G  QGPP          P G + P GPP           PG+P
Sbjct: 183 PSGPRGLPGPPGAPGPQG-FQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRP 241

Query: 200 --QGPP-PQG----------------------DKSRSSQSPPGKPQGPPPQGGNQ----- 229
             +GPP PQG                      D ++    P G P+G P   G       
Sbjct: 242 GERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG-PKGEPGSPGENGAPGQ 300

Query: 230 --PQGPPPPPGKPQGPPPQG--GNK----PQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281
             P+G P   G+P  P P G  GN       GPP P  P GPP   G+      + P  P
Sbjct: 301 MGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGP 360

Query: 282 QGPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           +G    +G     GPP PAG       A PAG P    +P   G    P
Sbjct: 361 RGSEGPQGVRGEPGPPGPAGA------AGPAGNPGADGQPGAKGANGAP 403



 Score =  111 bits (278), Expect = 8e-25
 Identities = 108/355 (30%), Positives = 134/355 (37%), Gaps = 61/355 (17%)

Query: 32  IAGNPQGPSPQGGNK-PQGPPPPPGKPQGPPPQGG--------NKPQGPPPPG--KPQGP 80
           +AG P+GP+ + G+  P GP   PG+  G P + G          P  P P G   P GP
Sbjct: 501 VAG-PKGPAGERGSPGPAGPKGSPGEA-GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558

Query: 81  PPQGDKSRSPRSPPGKPQG-----PPPQG-GNQP-----QGPPPPPGKPQGPPPQGGNRP 129
             Q  +   P  P  + Q      P P+G   +P     +G P PPG        G    
Sbjct: 559 AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618

Query: 130 QGPPPPGKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187
           QGPP P  P G   +   + SP  +  PG P GPP + G    G    PG    P P G 
Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPG-PAGPPGEAGK--PGEQGVPGDLGAPGPSGA 675

Query: 188 KKPQGPPPPGKPQGPP-PQGDKSRS-------SQSPPGKPQGPPPQGGNQPQGPPPPPGK 239
           +  +G P     QGPP P G +  +       ++   G P  P  QG    QG P   G 
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735

Query: 240 PQGPPPQGGNKPQGPP----PPGK--------PQGPPAQGGSKSQSARSPPGKPQGPPQQ 287
              P P+G     GP      PGK        P GPP   G+      S P  P GP   
Sbjct: 736 AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGA 795

Query: 288 EG----NNPQGPPPPAG--------GNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
            G        GPP PAG        G P     P     +G   PP    P+ PP
Sbjct: 796 RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850



 Score =  100 bits (248), Expect = 2e-21
 Identities = 74/235 (31%), Positives = 88/235 (37%), Gaps = 40/235 (17%)

Query: 33   AGNPQGPSPQGGNKPQGPPPPPGKP--QGPPPQGGNK--PQGPPPPGKPQGPPPQGDKSR 88
            +G P    P G +  +GPP P G P   GPP + G +  P     PG+   P  +GD+  
Sbjct: 979  SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038

Query: 89   S-PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP----- 142
            + P  PPG P  P   G   P G     G+     P G   P G   P  PQGP      
Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGE 1098

Query: 143  --PQGDKS----------RSPRSPPGKPQGPPPQGGNQPQGPPPPPGK------------ 178
               QGD+           + P  PPG P    P G + P GP  PPG             
Sbjct: 1099 TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGL 1158

Query: 179  --PQGPPPQGGKK----PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG 227
              P GPP   G+     P GPP P  P GPP            P  PQ     GG
Sbjct: 1159 PGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  145 bits (367), Expect = 4e-35
 Identities = 134/376 (35%), Positives = 153/376 (40%), Gaps = 81/376 (21%)

Query: 33   AGNPQG-PSPQGGNKPQGPPPPPGK--PQGPP-PQGGNKPQGPP-PPGK---PQGPPPQG 84
            A  P G P P+G +   GPP PPG+  PQGP  P G   P+GPP PPGK   P  P  +G
Sbjct: 905  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 964

Query: 85   DKS-RSPRSPPGK-----PQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134
            +   +    PPG      PQGP     P G     GPP PPG+   P   G    +G P 
Sbjct: 965  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1024

Query: 135  PGKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192
            P    G          P  R  PG    P  +GG  PQGPP P G P      G   P G
Sbjct: 1025 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1084

Query: 193  PPPPGKPQGPP-PQGDKS----RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----G 242
             P    PQGPP P G+K     +  Q P G+     P G   P GP   PG+       G
Sbjct: 1085 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1144

Query: 243  PPPQGGNK-------PQGPP----PPGKP--------QGPPAQGGSKSQ----SARSPPG 279
             P Q G+K       P GPP    P G P         GP  Q G   Q     AR  PG
Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1204

Query: 280  KP--------QGPPQQEGNN----PQGPPPPAGGNPQQPQAP-PAGQPQGPP-------- 318
             P         GPP ++G N    P GPP P G  P+ PQ P  A  PQGPP        
Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG--PRGPQGPNGADGPQGPPGSVGSVGG 1262

Query: 319  -----RPPQGGRPSRP 329
                  P + G P  P
Sbjct: 1263 VGEKGEPGEAGNPGPP 1278



 Score =  134 bits (338), Expect = 9e-32
 Identities = 136/396 (34%), Positives = 167/396 (42%), Gaps = 95/396 (23%)

Query: 21   EDVSQEESPSLIAGNP--------QG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP 71
            + +S ++ P+ + G P        QG P  +GG  PQGPP P G P      G   P G 
Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1085

Query: 72   PPPGKPQGPP-PQGDKS----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GP 121
            P    PQGPP P G+K     + P+ P G+     P G   P GP   PG+       G 
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145

Query: 122  PPQGG-------NRPQGPPPPGKPQGPP--PQGDKSRSPRSPPGK-----PQG----PPP 163
            P Q G       N P GPP    P G P    GD    PR   G       +G    P P
Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1205

Query: 164  QGGNQPQGPPPPPGK--------PQGPP-PQGGKKPQGPPPPGKPQGPPPQ-------GD 207
             G    QG P PPG+        P GPP P G + PQGP     PQGPP         G+
Sbjct: 1206 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1265

Query: 208  KSRSSQS----PPGKPQ--GPPPQGGNQPQGPPP----PPGKPQGPPPQGGNK------- 250
            K    ++    PPG+    GP  + G + +  PP    PPG  +GPP   G K       
Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA-KGPPGDDGPKGNPGPVG 1324

Query: 251  -PQGPPPPGKPQGPPAQ---GGSKSQSARSPPGKPQGPPQQEGN-NPQGPP----PP--A 299
             P  P PPG+P GP  Q   GG K +     PG+P GPP   G   P GPP    PP  A
Sbjct: 1325 FPGDPGPPGEP-GPAGQDGVGGDKGED--GDPGQP-GPPGPSGEAGPPGPPGKRGPPGAA 1380

Query: 300  GGNPQQPQAPPAGQ--PQGPPRP-----PQG--GRP 326
            G   +Q +    G+   +GPP       PQG  G+P
Sbjct: 1381 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1416



 Score =  132 bits (331), Expect = 6e-31
 Identities = 122/347 (35%), Positives = 143/347 (41%), Gaps = 60/347 (17%)

Query: 29   PSLIAGNPQGPSPQGGNK---PQGPPPPPGKPQGPP-PQGGNKPQGPP------------ 72
            P  + G P  P  +G N    P GPP PPG P+GP  P G + PQGPP            
Sbjct: 1208 PIGLQGLPGPPGEKGENGDVGPMGPPGPPG-PRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266

Query: 73   -PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNR 128
              PG+   P P G+     P+   G+     P G   P G   PPG   P+G P   G  
Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF- 1325

Query: 129  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---- 184
            P  P PPG+P GP  Q D     +   G P  P P G +   GPP PPGK +GPP     
Sbjct: 1326 PGDPGPPGEP-GPAGQ-DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK-RGPPGAAGA 1382

Query: 185  ---QGGKKPQGPP----PPGK-----PQGPP--PQGDKSRSSQSPPGKPQGPPPQGGNQP 230
               QG K  +G      PPGK     PQGP   P  +  R    P G+   P   G + P
Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1442

Query: 231  QGPPPPPGKP--QGPPPQGGNKPQ-------GPPPPGKPQG----PPAQG--GSKSQSAR 275
             GP  PPG P  +G P   G K         GPP     +G    P  QG  G+K     
Sbjct: 1443 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502

Query: 276  SPPGKPQGPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
              P  P GPP   G   PQGP    G      Q   +G P GPP  P
Sbjct: 1503 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP-GPPGSP 1548



 Score =  131 bits (329), Expect = 1e-30
 Identities = 131/403 (32%), Positives = 150/403 (37%), Gaps = 110/403 (27%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQG----PPPQGDK 86
           G    P PQG    QGPP P GKP     P   GG    G P     +G    P   GDK
Sbjct: 565 GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 624

Query: 87  S----RSPRSPPGKP--------------QGPPPQGGNQ----PQGPPPPPGKP-----Q 119
                R P+ PPG P              +G P + G +    P+G P  PG+P      
Sbjct: 625 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 684

Query: 120 GPP-PQGGNRPQGPP-PPGKPQGPPPQG-DKSRSPRSPPGK--PQGPPPQGGNQPQGPPP 174
           GPP P+G   PQG P PPG+   P PQG    + P  PPG+  PQG P   G    G   
Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP--GADG 742

Query: 175 PPGKPQGPPPQGGKKPQGPPPPGKPQGPPP------------------------------ 204
           PPG P      G K   GPP P  P G P                               
Sbjct: 743 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 802

Query: 205 ----QGDKSRSSQSPPGKPQGPP-PQGGNQPQGPPPP---------------PGKPQGPP 244
               +GD+    Q  P    GP  P+G   P G P P               PG P    
Sbjct: 803 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG 862

Query: 245 PQGGNKPQGPP----------PPGKPQGPPAQGGSK----SQSARSPPGKPQGPPQQEGN 290
           P+G     G P            GKP GP  Q G      S+ AR P GKP       G+
Sbjct: 863 PKGSTGFPGFPGANGEKGARGVAGKP-GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD 921

Query: 291 NPQGPPPPAGGNPQQPQAPPA-GQPQGPPRPP-QGGRPSRPPQ 331
            P GPP   G  PQ PQ P     P+GPP PP + G P  P Q
Sbjct: 922 GPPGPPGERG--PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ 962



 Score =  130 bits (326), Expect = 2e-30
 Identities = 127/390 (32%), Positives = 150/390 (38%), Gaps = 92/390 (23%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPP 81
            E  P    G+P  P P G     G     G    P PQG +   GP      PG+   P 
Sbjct: 989  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1048

Query: 82   PQG----DKSRSPRSPPGKPQGPPPQGGNQ-------------PQGPPPPPGK------- 117
             QG         P+ PPG P G P + G+              PQGPP P G+       
Sbjct: 1049 AQGAPGLKGGEGPQGPPG-PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1107

Query: 118  -PQGPPPQGG-NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP-- 173
             PQGP  + G   P G P P  P G P + D  +     PG+      +G N P GPP  
Sbjct: 1108 GPQGPAGRDGVQGPVGLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166

Query: 174  -PPPGKP--------QGPPPQGGKKPQ----------GPPPPGKPQG-PPPQGDKSRSSQ 213
              P G P         GP  Q G   Q          GPP P   QG P P G+K  +  
Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1226

Query: 214  SPPGKPQGPP----PQGGNQPQGPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQ 261
              P  P GPP    PQG N   GP  PPG          +G P + GN   GPP      
Sbjct: 1227 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN--PGPPGEAGVG 1284

Query: 262  GPPAQGGSKSQS----ARSPPGKPQGPPQQEGNNPQGPPPPAG--GNPQQPQAP-PAGQ- 313
            GP  + G K ++    A  PPG  +GPP  +G  P+G P P G  G+P  P  P PAGQ 
Sbjct: 1285 GPKGERGEKGEAGPPGAAGPPG-AKGPPGDDG--PKGNPGPVGFPGDPGPPGEPGPAGQD 1341

Query: 314  -------------PQGPPRPPQGGRPSRPP 330
                           GPP P     P  PP
Sbjct: 1342 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1371



 Score =  129 bits (323), Expect = 5e-30
 Identities = 107/301 (35%), Positives = 130/301 (43%), Gaps = 39/301 (12%)

Query: 62   PQGGNKPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119
            P+G + P+GP     P G P P G      +   PG P  P  QG   P+G    PG P 
Sbjct: 818  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG---PKGSTGFPGFPG 874

Query: 120  GPPPQGGNRPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178
                +G     G P P   +GP  P+G  SR  R P GKP    P+G +   GPP PPG+
Sbjct: 875  ANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGPTGKPG---PKGTSGGDGPPGPPGE 929

Query: 179  --PQGPP-PQGGKKPQGPP-PPGK---PQGPPPQGDKS-RSSQSPPGK-----PQGPP-- 223
              PQGP  P G   P+GPP PPGK   P  P  +G+   +    PPG      PQGP   
Sbjct: 930  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 989

Query: 224  --PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKS-QSARSPPGK 280
              P G     GPP PPG+   P   G    +G P P    G     G +     R  PG 
Sbjct: 990  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1049

Query: 281  PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--------PQGPPRP--PQGGRPSRPP 330
               P  + G  PQGPP P G   ++  A  AG         PQGPP P   +G    + P
Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1109

Query: 331  Q 331
            Q
Sbjct: 1110 Q 1110



 Score =  128 bits (322), Expect = 6e-30
 Identities = 121/358 (33%), Positives = 145/358 (40%), Gaps = 76/358 (21%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPP-----PQ 83
            +AG    P P+G   PQG P PPG+   P PQG   PQGP  PPG+  PQG P     P 
Sbjct: 680  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 739

Query: 84   GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--------------------- 122
             D    P   PGK      +G   P GP  P G P GP                      
Sbjct: 740  AD---GPPGHPGKEGQSGEKGALGPPGPQGPIGYP-GPRGVKGADGVRGLKGSKGEKGED 795

Query: 123  ----------------------PQGGNRPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKP 158
                                  P+G + P+GP     P G P P G      +   PG P
Sbjct: 796  GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 855

Query: 159  QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQSPPG 217
              P  QG   P+G    PG P     +G +   G P P   +GP  P+G  SR ++ P G
Sbjct: 856  GYPGRQG---PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGPTG 910

Query: 218  KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPP-PPGK---PQGPPAQGGSKSQ 272
            KP      GG+ P GPP   G PQGP  P G   P+GPP PPGK   P  P  +G +  Q
Sbjct: 911  KPGPKGTSGGDGPPGPPGERG-PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 969

Query: 273  SARSPPGK-----PQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQG 323
                PPG      PQGP  + G    +G P P G   +Q     AG+      P PQG
Sbjct: 970  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1027



 Score =  125 bits (315), Expect = 4e-29
 Identities = 113/320 (35%), Positives = 129/320 (40%), Gaps = 62/320 (19%)

Query: 29  PSLIAGNP--QGPS-PQGGNKPQGPPPPPGKP-----QGPPPQ--------GGNKPQGPP 72
           P+ I G P  QGP+ P G    +GPP  PG P      GPP          GG+  +GP 
Sbjct: 461 PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT 520

Query: 73  ---------------------PPGKPQG----PPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
                                PPG P G    P P G    S     G+   P PQG   
Sbjct: 521 ISAQEAQAQAILQQARIALRGPPG-PMGLTGRPGPVGGPGSS--GAKGESGDPGPQGPRG 577

Query: 108 PQGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
            QGPP P GKP  +G P   G R       G P  P  +GD+       PG P     +G
Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGR-------GMPGEPGAKGDRGFD--GLPGLPGDKGHRG 628

Query: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP-PPQGDKSRSSQSPPGKPQGPP- 223
              PQGPP PPG        G   P+G P    P+G   P+G      Q       GPP 
Sbjct: 629 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688

Query: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPPAQGGSKSQSARSPPGK 280
           P+G   PQG P PPG+   P PQG   PQGP  PPG+  PQG P   G     A  PPG 
Sbjct: 689 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG--LPGADGPPGH 746

Query: 281 PQGPPQQEGNNPQGPPPPAG 300
           P    Q       GPP P G
Sbjct: 747 PGKEGQSGEKGALGPPGPQG 766



 Score =  121 bits (304), Expect = 8e-28
 Identities = 119/387 (30%), Positives = 141/387 (36%), Gaps = 98/387 (25%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGK--PQGPP----------PQG-----GNKPQ------- 69
            G P     +G     GPP PPG   P G P          P+G     G K         
Sbjct: 1144 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1203

Query: 70   GPPPPGKPQG-PPPQGDKSRS----PRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 117
            GPP P   QG P P G+K  +    P  PPG P    PQG N   GP  PPG        
Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1263

Query: 118  -PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP----PQGGNQPQGP 172
              +G P + GN    P PPG+     P+G++     + P    GPP    P G + P+G 
Sbjct: 1264 GEKGEPGEAGN----PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319

Query: 173  PPPPGKPQGPPPQGGKKPQGPP----------PPGKPQGPPPQGDKSRSSQSPPGKPQGP 222
            P P G P  P P G   P G             PG+P  P P G+       PPGK   P
Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG--PPGPPGKRGPP 1377

Query: 223  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKP--------QGPPAQGGSKSQS 273
               G    QG     G+     P G   P GP  P GKP         GP  + G    +
Sbjct: 1378 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1437

Query: 274  ARSPPGKPQGPP-----------QQEGNNPQ-----GPPPPAG-----GNPQQPQAP--- 309
             +  P  P GPP           + E  +P      GPP   G     G P    +P   
Sbjct: 1438 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1497

Query: 310  -------PAGQPQGPPRPPQGGRPSRP 329
                   PAG P GPP PP    P  P
Sbjct: 1498 GDGGIPGPAG-PLGPPGPPGLPGPQGP 1523



 Score =  113 bits (282), Expect = 3e-25
 Identities = 108/328 (32%), Positives = 133/328 (40%), Gaps = 55/328 (16%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           P ++   P GP+   G    GPP   G P GPP   G++     PPG+P  P   G    
Sbjct: 448 PGMLVEGPPGPAGPAGI--MGPPGLQG-PTGPPGDPGDRG----PPGRPGLPGADG---- 496

Query: 89  SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNRPQGPPPP-GKPQGPPPQG 145
            P  P      P   GG+  +GP     + Q      Q     +GPP P G    P P G
Sbjct: 497 LPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVG 556

Query: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGKKPQGPPPPGKPQGPP 203
               S     G+   P PQG    QGPP P GKP  +G P   G +       G P  P 
Sbjct: 557 GPGSS--GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR-------GMPGEPG 607

Query: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK-----------PQGPPPQGGNK-- 250
            +GD  R     PG P     +G   PQGPP PPG            P+G P + G +  
Sbjct: 608 AKGD--RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 665

Query: 251 --PQGPP-PPGKP-----QGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAGG 301
             P+G P  PG+P      GPP   G+       P G+P GPP Q+GN  PQG P P G 
Sbjct: 666 LGPRGTPGAPGQPGMAGVDGPPGPKGN-----MGPQGEP-GPPGQQGNPGPQGLPGPQGP 719

Query: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
                +  P G+P     P   G P  P
Sbjct: 720 IGPPGEKGPQGKPGLAGLPGADGPPGHP 747



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 60/170 (35%), Positives = 64/170 (37%), Gaps = 31/170 (18%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKP--------------QGPPPQGGNKPQGPPPPGKPQG 79
            G      P G   P GP  P GKP              QG P   G    GPP P  P G
Sbjct: 1393 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ--DGPPGPMGPPG 1450

Query: 80   -PPPQGDK-SRSPRSPPGKPQ--GPP-PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP-P 133
             P  +GD  S+  +  PG     GPP  QG    +G P   G P      G   P GP  
Sbjct: 1451 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1510

Query: 134  PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
            PPG P  P PQG        P G      P G     G P PPG P GPP
Sbjct: 1511 PPGPPGLPGPQG--------PKGNKGSTGPAGQKGDSGLPGPPGSP-GPP 1551



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 26/102 (25%)

Query: 239 KPQGPPPQGGNKPQGPPPPGKPQ---------GPPAQGGSKSQSARSPPGK-PQGPPQQE 288
           KP  PP    N+  GP  P +           G   + G K + A   PG   +GPP   
Sbjct: 404 KPTSPP----NEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPA 459

Query: 289 G----------NNPQGPPPPAG--GNPQQPQAPPAGQPQGPP 318
           G            P GPP   G  G P +P  P A    GPP
Sbjct: 460 GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  145 bits (367), Expect = 4e-35
 Identities = 134/376 (35%), Positives = 153/376 (40%), Gaps = 81/376 (21%)

Query: 33   AGNPQG-PSPQGGNKPQGPPPPPGK--PQGPP-PQGGNKPQGPP-PPGK---PQGPPPQG 84
            A  P G P P+G +   GPP PPG+  PQGP  P G   P+GPP PPGK   P  P  +G
Sbjct: 854  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 913

Query: 85   DKS-RSPRSPPGK-----PQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134
            +   +    PPG      PQGP     P G     GPP PPG+   P   G    +G P 
Sbjct: 914  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973

Query: 135  PGKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192
            P    G          P  R  PG    P  +GG  PQGPP P G P      G   P G
Sbjct: 974  PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1033

Query: 193  PPPPGKPQGPP-PQGDKS----RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----G 242
             P    PQGPP P G+K     +  Q P G+     P G   P GP   PG+       G
Sbjct: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1093

Query: 243  PPPQGGNK-------PQGPP----PPGKP--------QGPPAQGGSKSQ----SARSPPG 279
             P Q G+K       P GPP    P G P         GP  Q G   Q     AR  PG
Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1153

Query: 280  KP--------QGPPQQEGNN----PQGPPPPAGGNPQQPQAP-PAGQPQGPP-------- 318
             P         GPP ++G N    P GPP P G  P+ PQ P  A  PQGPP        
Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG--PRGPQGPNGADGPQGPPGSVGSVGG 1211

Query: 319  -----RPPQGGRPSRP 329
                  P + G P  P
Sbjct: 1212 VGEKGEPGEAGNPGPP 1227



 Score =  134 bits (338), Expect = 9e-32
 Identities = 136/396 (34%), Positives = 167/396 (42%), Gaps = 95/396 (23%)

Query: 21   EDVSQEESPSLIAGNP--------QG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP 71
            + +S ++ P+ + G P        QG P  +GG  PQGPP P G P      G   P G 
Sbjct: 975  QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034

Query: 72   PPPGKPQGPP-PQGDKS----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GP 121
            P    PQGPP P G+K     + P+ P G+     P G   P GP   PG+       G 
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094

Query: 122  PPQGG-------NRPQGPPPPGKPQGPP--PQGDKSRSPRSPPGK-----PQG----PPP 163
            P Q G       N P GPP    P G P    GD    PR   G       +G    P P
Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1154

Query: 164  QGGNQPQGPPPPPGK--------PQGPP-PQGGKKPQGPPPPGKPQGPPPQ-------GD 207
             G    QG P PPG+        P GPP P G + PQGP     PQGPP         G+
Sbjct: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1214

Query: 208  KSRSSQS----PPGKPQ--GPPPQGGNQPQGPPP----PPGKPQGPPPQGGNK------- 250
            K    ++    PPG+    GP  + G + +  PP    PPG  +GPP   G K       
Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA-KGPPGDDGPKGNPGPVG 1273

Query: 251  -PQGPPPPGKPQGPPAQ---GGSKSQSARSPPGKPQGPPQQEGN-NPQGPP----PP--A 299
             P  P PPG+P GP  Q   GG K +     PG+P GPP   G   P GPP    PP  A
Sbjct: 1274 FPGDPGPPGEP-GPAGQDGVGGDKGED--GDPGQP-GPPGPSGEAGPPGPPGKRGPPGAA 1329

Query: 300  GGNPQQPQAPPAGQ--PQGPPRP-----PQG--GRP 326
            G   +Q +    G+   +GPP       PQG  G+P
Sbjct: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365



 Score =  132 bits (331), Expect = 6e-31
 Identities = 122/347 (35%), Positives = 143/347 (41%), Gaps = 60/347 (17%)

Query: 29   PSLIAGNPQGPSPQGGNK---PQGPPPPPGKPQGPP-PQGGNKPQGPP------------ 72
            P  + G P  P  +G N    P GPP PPG P+GP  P G + PQGPP            
Sbjct: 1157 PIGLQGLPGPPGEKGENGDVGPMGPPGPPG-PRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215

Query: 73   -PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNR 128
              PG+   P P G+     P+   G+     P G   P G   PPG   P+G P   G  
Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF- 1274

Query: 129  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---- 184
            P  P PPG+P GP  Q D     +   G P  P P G +   GPP PPGK +GPP     
Sbjct: 1275 PGDPGPPGEP-GPAGQ-DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK-RGPPGAAGA 1331

Query: 185  ---QGGKKPQGPP----PPGK-----PQGPP--PQGDKSRSSQSPPGKPQGPPPQGGNQP 230
               QG K  +G      PPGK     PQGP   P  +  R    P G+   P   G + P
Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1391

Query: 231  QGPPPPPGKP--QGPPPQGGNKPQ-------GPPPPGKPQG----PPAQG--GSKSQSAR 275
             GP  PPG P  +G P   G K         GPP     +G    P  QG  G+K     
Sbjct: 1392 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451

Query: 276  SPPGKPQGPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
              P  P GPP   G   PQGP    G      Q   +G P GPP  P
Sbjct: 1452 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP-GPPGSP 1497



 Score =  131 bits (329), Expect = 1e-30
 Identities = 131/403 (32%), Positives = 150/403 (37%), Gaps = 110/403 (27%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQG----PPPQGDK 86
           G    P PQG    QGPP P GKP     P   GG    G P     +G    P   GDK
Sbjct: 514 GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573

Query: 87  S----RSPRSPPGKP--------------QGPPPQGGNQ----PQGPPPPPGKP-----Q 119
                R P+ PPG P              +G P + G +    P+G P  PG+P      
Sbjct: 574 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 120 GPP-PQGGNRPQGPP-PPGKPQGPPPQG-DKSRSPRSPPGK--PQGPPPQGGNQPQGPPP 174
           GPP P+G   PQG P PPG+   P PQG    + P  PPG+  PQG P   G    G   
Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP--GADG 691

Query: 175 PPGKPQGPPPQGGKKPQGPPPPGKPQGPPP------------------------------ 204
           PPG P      G K   GPP P  P G P                               
Sbjct: 692 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 751

Query: 205 ----QGDKSRSSQSPPGKPQGPP-PQGGNQPQGPPPP---------------PGKPQGPP 244
               +GD+    Q  P    GP  P+G   P G P P               PG P    
Sbjct: 752 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG 811

Query: 245 PQGGNKPQGPP----------PPGKPQGPPAQGGSK----SQSARSPPGKPQGPPQQEGN 290
           P+G     G P            GKP GP  Q G      S+ AR P GKP       G+
Sbjct: 812 PKGSTGFPGFPGANGEKGARGVAGKP-GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD 870

Query: 291 NPQGPPPPAGGNPQQPQAPPA-GQPQGPPRPP-QGGRPSRPPQ 331
            P GPP   G  PQ PQ P     P+GPP PP + G P  P Q
Sbjct: 871 GPPGPPGERG--PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ 911



 Score =  130 bits (326), Expect = 2e-30
 Identities = 127/390 (32%), Positives = 150/390 (38%), Gaps = 92/390 (23%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPP 81
            E  P    G+P  P P G     G     G    P PQG +   GP      PG+   P 
Sbjct: 938  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997

Query: 82   PQG----DKSRSPRSPPGKPQGPPPQGGNQ-------------PQGPPPPPGK------- 117
             QG         P+ PPG P G P + G+              PQGPP P G+       
Sbjct: 998  AQGAPGLKGGEGPQGPPG-PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1056

Query: 118  -PQGPPPQGG-NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP-- 173
             PQGP  + G   P G P P  P G P + D  +     PG+      +G N P GPP  
Sbjct: 1057 GPQGPAGRDGVQGPVGLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115

Query: 174  -PPPGKP--------QGPPPQGGKKPQ----------GPPPPGKPQG-PPPQGDKSRSSQ 213
              P G P         GP  Q G   Q          GPP P   QG P P G+K  +  
Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1175

Query: 214  SPPGKPQGPP----PQGGNQPQGPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQ 261
              P  P GPP    PQG N   GP  PPG          +G P + GN   GPP      
Sbjct: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN--PGPPGEAGVG 1233

Query: 262  GPPAQGGSKSQS----ARSPPGKPQGPPQQEGNNPQGPPPPAG--GNPQQPQAP-PAGQ- 313
            GP  + G K ++    A  PPG  +GPP  +G  P+G P P G  G+P  P  P PAGQ 
Sbjct: 1234 GPKGERGEKGEAGPPGAAGPPG-AKGPPGDDG--PKGNPGPVGFPGDPGPPGEPGPAGQD 1290

Query: 314  -------------PQGPPRPPQGGRPSRPP 330
                           GPP P     P  PP
Sbjct: 1291 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320



 Score =  129 bits (323), Expect = 5e-30
 Identities = 107/301 (35%), Positives = 130/301 (43%), Gaps = 39/301 (12%)

Query: 62   PQGGNKPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119
            P+G + P+GP     P G P P G      +   PG P  P  QG   P+G    PG P 
Sbjct: 767  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG---PKGSTGFPGFPG 823

Query: 120  GPPPQGGNRPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178
                +G     G P P   +GP  P+G  SR  R P GKP    P+G +   GPP PPG+
Sbjct: 824  ANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGPTGKPG---PKGTSGGDGPPGPPGE 878

Query: 179  --PQGPP-PQGGKKPQGPP-PPGK---PQGPPPQGDKS-RSSQSPPGK-----PQGPP-- 223
              PQGP  P G   P+GPP PPGK   P  P  +G+   +    PPG      PQGP   
Sbjct: 879  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 938

Query: 224  --PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKS-QSARSPPGK 280
              P G     GPP PPG+   P   G    +G P P    G     G +     R  PG 
Sbjct: 939  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 998

Query: 281  PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--------PQGPPRP--PQGGRPSRPP 330
               P  + G  PQGPP P G   ++  A  AG         PQGPP P   +G    + P
Sbjct: 999  QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1058

Query: 331  Q 331
            Q
Sbjct: 1059 Q 1059



 Score =  128 bits (322), Expect = 6e-30
 Identities = 121/358 (33%), Positives = 145/358 (40%), Gaps = 76/358 (21%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPP-----PQ 83
           +AG    P P+G   PQG P PPG+   P PQG   PQGP  PPG+  PQG P     P 
Sbjct: 629 MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 688

Query: 84  GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--------------------- 122
            D    P   PGK      +G   P GP  P G P GP                      
Sbjct: 689 AD---GPPGHPGKEGQSGEKGALGPPGPQGPIGYP-GPRGVKGADGVRGLKGSKGEKGED 744

Query: 123 ----------------------PQGGNRPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKP 158
                                 P+G + P+GP     P G P P G      +   PG P
Sbjct: 745 GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 804

Query: 159 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQSPPG 217
             P  QG   P+G    PG P     +G +   G P P   +GP  P+G  SR ++ P G
Sbjct: 805 GYPGRQG---PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGPTG 859

Query: 218 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPP-PPGK---PQGPPAQGGSKSQ 272
           KP      GG+ P GPP   G PQGP  P G   P+GPP PPGK   P  P  +G +  Q
Sbjct: 860 KPGPKGTSGGDGPPGPPGERG-PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918

Query: 273 SARSPPGK-----PQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQG 323
               PPG      PQGP  + G    +G P P G   +Q     AG+      P PQG
Sbjct: 919 GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 976



 Score =  125 bits (315), Expect = 4e-29
 Identities = 113/320 (35%), Positives = 129/320 (40%), Gaps = 62/320 (19%)

Query: 29  PSLIAGNP--QGPS-PQGGNKPQGPPPPPGKP-----QGPPPQ--------GGNKPQGPP 72
           P+ I G P  QGP+ P G    +GPP  PG P      GPP          GG+  +GP 
Sbjct: 410 PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT 469

Query: 73  ---------------------PPGKPQG----PPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
                                PPG P G    P P G    S     G+   P PQG   
Sbjct: 470 ISAQEAQAQAILQQARIALRGPPG-PMGLTGRPGPVGGPGSS--GAKGESGDPGPQGPRG 526

Query: 108 PQGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
            QGPP P GKP  +G P   G R       G P  P  +GD+       PG P     +G
Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGR-------GMPGEPGAKGDRGFD--GLPGLPGDKGHRG 577

Query: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP-PPQGDKSRSSQSPPGKPQGPP- 223
              PQGPP PPG        G   P+G P    P+G   P+G      Q       GPP 
Sbjct: 578 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637

Query: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPPAQGGSKSQSARSPPGK 280
           P+G   PQG P PPG+   P PQG   PQGP  PPG+  PQG P   G     A  PPG 
Sbjct: 638 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG--LPGADGPPGH 695

Query: 281 PQGPPQQEGNNPQGPPPPAG 300
           P    Q       GPP P G
Sbjct: 696 PGKEGQSGEKGALGPPGPQG 715



 Score =  121 bits (304), Expect = 8e-28
 Identities = 119/387 (30%), Positives = 141/387 (36%), Gaps = 98/387 (25%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGK--PQGPP----------PQG-----GNKPQ------- 69
            G P     +G     GPP PPG   P G P          P+G     G K         
Sbjct: 1093 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1152

Query: 70   GPPPPGKPQG-PPPQGDKSRS----PRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 117
            GPP P   QG P P G+K  +    P  PPG P    PQG N   GP  PPG        
Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1212

Query: 118  -PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP----PQGGNQPQGP 172
              +G P + GN    P PPG+     P+G++     + P    GPP    P G + P+G 
Sbjct: 1213 GEKGEPGEAGN----PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268

Query: 173  PPPPGKPQGPPPQGGKKPQGPP----------PPGKPQGPPPQGDKSRSSQSPPGKPQGP 222
            P P G P  P P G   P G             PG+P  P P G+       PPGK   P
Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG--PPGPPGKRGPP 1326

Query: 223  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKP--------QGPPAQGGSKSQS 273
               G    QG     G+     P G   P GP  P GKP         GP  + G    +
Sbjct: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1386

Query: 274  ARSPPGKPQGPP-----------QQEGNNPQ-----GPPPPAG-----GNPQQPQAP--- 309
             +  P  P GPP           + E  +P      GPP   G     G P    +P   
Sbjct: 1387 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1446

Query: 310  -------PAGQPQGPPRPPQGGRPSRP 329
                   PAG P GPP PP    P  P
Sbjct: 1447 GDGGIPGPAG-PLGPPGPPGLPGPQGP 1472



 Score =  113 bits (282), Expect = 3e-25
 Identities = 108/328 (32%), Positives = 133/328 (40%), Gaps = 55/328 (16%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           P ++   P GP+   G    GPP   G P GPP   G++     PPG+P  P   G    
Sbjct: 397 PGMLVEGPPGPAGPAGI--MGPPGLQG-PTGPPGDPGDRG----PPGRPGLPGADG---- 445

Query: 89  SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNRPQGPPPP-GKPQGPPPQG 145
            P  P      P   GG+  +GP     + Q      Q     +GPP P G    P P G
Sbjct: 446 LPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVG 505

Query: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGKKPQGPPPPGKPQGPP 203
               S     G+   P PQG    QGPP P GKP  +G P   G +       G P  P 
Sbjct: 506 GPGSS--GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR-------GMPGEPG 556

Query: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK-----------PQGPPPQGGNK-- 250
            +GD  R     PG P     +G   PQGPP PPG            P+G P + G +  
Sbjct: 557 AKGD--RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 614

Query: 251 --PQGPP-PPGKP-----QGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAGG 301
             P+G P  PG+P      GPP   G+       P G+P GPP Q+GN  PQG P P G 
Sbjct: 615 LGPRGTPGAPGQPGMAGVDGPPGPKGN-----MGPQGEP-GPPGQQGNPGPQGLPGPQGP 668

Query: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
                +  P G+P     P   G P  P
Sbjct: 669 IGPPGEKGPQGKPGLAGLPGADGPPGHP 696



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 60/170 (35%), Positives = 64/170 (37%), Gaps = 31/170 (18%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKP--------------QGPPPQGGNKPQGPPPPGKPQG 79
            G      P G   P GP  P GKP              QG P   G    GPP P  P G
Sbjct: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ--DGPPGPMGPPG 1399

Query: 80   -PPPQGDK-SRSPRSPPGKPQ--GPP-PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP-P 133
             P  +GD  S+  +  PG     GPP  QG    +G P   G P      G   P GP  
Sbjct: 1400 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1459

Query: 134  PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
            PPG P  P PQG        P G      P G     G P PPG P GPP
Sbjct: 1460 PPGPPGLPGPQG--------PKGNKGSTGPAGQKGDSGLPGPPGSP-GPP 1500



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 26/102 (25%)

Query: 239 KPQGPPPQGGNKPQGPPPPGKPQ---------GPPAQGGSKSQSARSPPGK-PQGPPQQE 288
           KP  PP    N+  GP  P +           G   + G K + A   PG   +GPP   
Sbjct: 353 KPTSPP----NEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPA 408

Query: 289 G----------NNPQGPPPPAG--GNPQQPQAPPAGQPQGPP 318
           G            P GPP   G  G P +P  P A    GPP
Sbjct: 409 GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  145 bits (367), Expect = 4e-35
 Identities = 134/376 (35%), Positives = 153/376 (40%), Gaps = 81/376 (21%)

Query: 33   AGNPQG-PSPQGGNKPQGPPPPPGK--PQGPP-PQGGNKPQGPP-PPGK---PQGPPPQG 84
            A  P G P P+G +   GPP PPG+  PQGP  P G   P+GPP PPGK   P  P  +G
Sbjct: 893  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 952

Query: 85   DKS-RSPRSPPGK-----PQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134
            +   +    PPG      PQGP     P G     GPP PPG+   P   G    +G P 
Sbjct: 953  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1012

Query: 135  PGKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192
            P    G          P  R  PG    P  +GG  PQGPP P G P      G   P G
Sbjct: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIG 1072

Query: 193  PPPPGKPQGPP-PQGDKS----RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----G 242
             P    PQGPP P G+K     +  Q P G+     P G   P GP   PG+       G
Sbjct: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG 1132

Query: 243  PPPQGGNK-------PQGPP----PPGKP--------QGPPAQGGSKSQ----SARSPPG 279
             P Q G+K       P GPP    P G P         GP  Q G   Q     AR  PG
Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG 1192

Query: 280  KP--------QGPPQQEGNN----PQGPPPPAGGNPQQPQAP-PAGQPQGPP-------- 318
             P         GPP ++G N    P GPP P G  P+ PQ P  A  PQGPP        
Sbjct: 1193 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG--PRGPQGPNGADGPQGPPGSVGSVGG 1250

Query: 319  -----RPPQGGRPSRP 329
                  P + G P  P
Sbjct: 1251 VGEKGEPGEAGNPGPP 1266



 Score =  134 bits (338), Expect = 9e-32
 Identities = 136/396 (34%), Positives = 167/396 (42%), Gaps = 95/396 (23%)

Query: 21   EDVSQEESPSLIAGNP--------QG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP 71
            + +S ++ P+ + G P        QG P  +GG  PQGPP P G P      G   P G 
Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073

Query: 72   PPPGKPQGPP-PQGDKS----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GP 121
            P    PQGPP P G+K     + P+ P G+     P G   P GP   PG+       G 
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133

Query: 122  PPQGG-------NRPQGPPPPGKPQGPP--PQGDKSRSPRSPPGK-----PQG----PPP 163
            P Q G       N P GPP    P G P    GD    PR   G       +G    P P
Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1193

Query: 164  QGGNQPQGPPPPPGK--------PQGPP-PQGGKKPQGPPPPGKPQGPPPQ-------GD 207
             G    QG P PPG+        P GPP P G + PQGP     PQGPP         G+
Sbjct: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1253

Query: 208  KSRSSQS----PPGKPQ--GPPPQGGNQPQGPPP----PPGKPQGPPPQGGNK------- 250
            K    ++    PPG+    GP  + G + +  PP    PPG  +GPP   G K       
Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA-KGPPGDDGPKGNPGPVG 1312

Query: 251  -PQGPPPPGKPQGPPAQ---GGSKSQSARSPPGKPQGPPQQEGN-NPQGPP----PP--A 299
             P  P PPG+P GP  Q   GG K +     PG+P GPP   G   P GPP    PP  A
Sbjct: 1313 FPGDPGPPGEP-GPAGQDGVGGDKGED--GDPGQP-GPPGPSGEAGPPGPPGKRGPPGAA 1368

Query: 300  GGNPQQPQAPPAGQ--PQGPPRP-----PQG--GRP 326
            G   +Q +    G+   +GPP       PQG  G+P
Sbjct: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404



 Score =  132 bits (331), Expect = 6e-31
 Identities = 122/347 (35%), Positives = 143/347 (41%), Gaps = 60/347 (17%)

Query: 29   PSLIAGNPQGPSPQGGNK---PQGPPPPPGKPQGPP-PQGGNKPQGPP------------ 72
            P  + G P  P  +G N    P GPP PPG P+GP  P G + PQGPP            
Sbjct: 1196 PIGLQGLPGPPGEKGENGDVGPMGPPGPPG-PRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254

Query: 73   -PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNR 128
              PG+   P P G+     P+   G+     P G   P G   PPG   P+G P   G  
Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF- 1313

Query: 129  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---- 184
            P  P PPG+P GP  Q D     +   G P  P P G +   GPP PPGK +GPP     
Sbjct: 1314 PGDPGPPGEP-GPAGQ-DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK-RGPPGAAGA 1370

Query: 185  ---QGGKKPQGPP----PPGK-----PQGPP--PQGDKSRSSQSPPGKPQGPPPQGGNQP 230
               QG K  +G      PPGK     PQGP   P  +  R    P G+   P   G + P
Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1430

Query: 231  QGPPPPPGKP--QGPPPQGGNKPQ-------GPPPPGKPQG----PPAQG--GSKSQSAR 275
             GP  PPG P  +G P   G K         GPP     +G    P  QG  G+K     
Sbjct: 1431 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490

Query: 276  SPPGKPQGPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
              P  P GPP   G   PQGP    G      Q   +G P GPP  P
Sbjct: 1491 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP-GPPGSP 1536



 Score =  131 bits (329), Expect = 1e-30
 Identities = 131/403 (32%), Positives = 150/403 (37%), Gaps = 110/403 (27%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQG---PPPQGGNKPQGPPPPGKPQG----PPPQGDK 86
           G    P PQG    QGPP P GKP     P   GG    G P     +G    P   GDK
Sbjct: 553 GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612

Query: 87  S----RSPRSPPGKP--------------QGPPPQGGNQ----PQGPPPPPGKP-----Q 119
                R P+ PPG P              +G P + G +    P+G P  PG+P      
Sbjct: 613 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 672

Query: 120 GPP-PQGGNRPQGPP-PPGKPQGPPPQG-DKSRSPRSPPGK--PQGPPPQGGNQPQGPPP 174
           GPP P+G   PQG P PPG+   P PQG    + P  PPG+  PQG P   G    G   
Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP--GADG 730

Query: 175 PPGKPQGPPPQGGKKPQGPPPPGKPQGPPP------------------------------ 204
           PPG P      G K   GPP P  P G P                               
Sbjct: 731 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKG 790

Query: 205 ----QGDKSRSSQSPPGKPQGPP-PQGGNQPQGPPPP---------------PGKPQGPP 244
               +GD+    Q  P    GP  P+G   P G P P               PG P    
Sbjct: 791 DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG 850

Query: 245 PQGGNKPQGPP----------PPGKPQGPPAQGGSK----SQSARSPPGKPQGPPQQEGN 290
           P+G     G P            GKP GP  Q G      S+ AR P GKP       G+
Sbjct: 851 PKGSTGFPGFPGANGEKGARGVAGKP-GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD 909

Query: 291 NPQGPPPPAGGNPQQPQAPPA-GQPQGPPRPP-QGGRPSRPPQ 331
            P GPP   G  PQ PQ P     P+GPP PP + G P  P Q
Sbjct: 910 GPPGPPGERG--PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ 950



 Score =  130 bits (326), Expect = 2e-30
 Identities = 127/390 (32%), Positives = 150/390 (38%), Gaps = 92/390 (23%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPP 81
            E  P    G+P  P P G     G     G    P PQG +   GP      PG+   P 
Sbjct: 977  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036

Query: 82   PQG----DKSRSPRSPPGKPQGPPPQGGNQ-------------PQGPPPPPGK------- 117
             QG         P+ PPG P G P + G+              PQGPP P G+       
Sbjct: 1037 AQGAPGLKGGEGPQGPPG-PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1095

Query: 118  -PQGPPPQGG-NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP-- 173
             PQGP  + G   P G P P  P G P + D  +     PG+      +G N P GPP  
Sbjct: 1096 GPQGPAGRDGVQGPVGLPGPAGPAGSPGE-DGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154

Query: 174  -PPPGKP--------QGPPPQGGKKPQ----------GPPPPGKPQG-PPPQGDKSRSSQ 213
              P G P         GP  Q G   Q          GPP P   QG P P G+K  +  
Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1214

Query: 214  SPPGKPQGPP----PQGGNQPQGPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQ 261
              P  P GPP    PQG N   GP  PPG          +G P + GN   GPP      
Sbjct: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN--PGPPGEAGVG 1272

Query: 262  GPPAQGGSKSQS----ARSPPGKPQGPPQQEGNNPQGPPPPAG--GNPQQPQAP-PAGQ- 313
            GP  + G K ++    A  PPG  +GPP  +G  P+G P P G  G+P  P  P PAGQ 
Sbjct: 1273 GPKGERGEKGEAGPPGAAGPPG-AKGPPGDDG--PKGNPGPVGFPGDPGPPGEPGPAGQD 1329

Query: 314  -------------PQGPPRPPQGGRPSRPP 330
                           GPP P     P  PP
Sbjct: 1330 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359



 Score =  129 bits (323), Expect = 5e-30
 Identities = 107/301 (35%), Positives = 130/301 (43%), Gaps = 39/301 (12%)

Query: 62   PQGGNKPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119
            P+G + P+GP     P G P P G      +   PG P  P  QG   P+G    PG P 
Sbjct: 806  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG---PKGSTGFPGFPG 862

Query: 120  GPPPQGGNRPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178
                +G     G P P   +GP  P+G  SR  R P GKP    P+G +   GPP PPG+
Sbjct: 863  ANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGPTGKPG---PKGTSGGDGPPGPPGE 917

Query: 179  --PQGPP-PQGGKKPQGPP-PPGK---PQGPPPQGDKS-RSSQSPPGK-----PQGPP-- 223
              PQGP  P G   P+GPP PPGK   P  P  +G+   +    PPG      PQGP   
Sbjct: 918  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 977

Query: 224  --PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKS-QSARSPPGK 280
              P G     GPP PPG+   P   G    +G P P    G     G +     R  PG 
Sbjct: 978  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1037

Query: 281  PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ--------PQGPPRP--PQGGRPSRPP 330
               P  + G  PQGPP P G   ++  A  AG         PQGPP P   +G    + P
Sbjct: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1097

Query: 331  Q 331
            Q
Sbjct: 1098 Q 1098



 Score =  128 bits (322), Expect = 6e-30
 Identities = 121/358 (33%), Positives = 145/358 (40%), Gaps = 76/358 (21%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPP-----PQ 83
            +AG    P P+G   PQG P PPG+   P PQG   PQGP  PPG+  PQG P     P 
Sbjct: 668  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 727

Query: 84   GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--------------------- 122
             D    P   PGK      +G   P GP  P G P GP                      
Sbjct: 728  AD---GPPGHPGKEGQSGEKGALGPPGPQGPIGYP-GPRGVKGADGVRGLKGSKGEKGED 783

Query: 123  ----------------------PQGGNRPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKP 158
                                  P+G + P+GP     P G P P G      +   PG P
Sbjct: 784  GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 843

Query: 159  QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQSPPG 217
              P  QG   P+G    PG P     +G +   G P P   +GP  P+G  SR ++ P G
Sbjct: 844  GYPGRQG---PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGPTG 898

Query: 218  KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPP-PPGK---PQGPPAQGGSKSQ 272
            KP      GG+ P GPP   G PQGP  P G   P+GPP PPGK   P  P  +G +  Q
Sbjct: 899  KPGPKGTSGGDGPPGPPGERG-PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957

Query: 273  SARSPPGK-----PQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQG 323
                PPG      PQGP  + G    +G P P G   +Q     AG+      P PQG
Sbjct: 958  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1015



 Score =  125 bits (315), Expect = 4e-29
 Identities = 113/320 (35%), Positives = 129/320 (40%), Gaps = 62/320 (19%)

Query: 29  PSLIAGNP--QGPS-PQGGNKPQGPPPPPGKP-----QGPPPQ--------GGNKPQGPP 72
           P+ I G P  QGP+ P G    +GPP  PG P      GPP          GG+  +GP 
Sbjct: 449 PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPT 508

Query: 73  ---------------------PPGKPQG----PPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
                                PPG P G    P P G    S     G+   P PQG   
Sbjct: 509 ISAQEAQAQAILQQARIALRGPPG-PMGLTGRPGPVGGPGSS--GAKGESGDPGPQGPRG 565

Query: 108 PQGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
            QGPP P GKP  +G P   G R       G P  P  +GD+       PG P     +G
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGR-------GMPGEPGAKGDRGFD--GLPGLPGDKGHRG 616

Query: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP-PPQGDKSRSSQSPPGKPQGPP- 223
              PQGPP PPG        G   P+G P    P+G   P+G      Q       GPP 
Sbjct: 617 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676

Query: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPPAQGGSKSQSARSPPGK 280
           P+G   PQG P PPG+   P PQG   PQGP  PPG+  PQG P   G     A  PPG 
Sbjct: 677 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG--LPGADGPPGH 734

Query: 281 PQGPPQQEGNNPQGPPPPAG 300
           P    Q       GPP P G
Sbjct: 735 PGKEGQSGEKGALGPPGPQG 754



 Score =  121 bits (304), Expect = 8e-28
 Identities = 119/387 (30%), Positives = 141/387 (36%), Gaps = 98/387 (25%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGK--PQGPP----------PQG-----GNKPQ------- 69
            G P     +G     GPP PPG   P G P          P+G     G K         
Sbjct: 1132 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1191

Query: 70   GPPPPGKPQG-PPPQGDKSRS----PRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 117
            GPP P   QG P P G+K  +    P  PPG P    PQG N   GP  PPG        
Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1251

Query: 118  -PQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP----PQGGNQPQGP 172
              +G P + GN    P PPG+     P+G++     + P    GPP    P G + P+G 
Sbjct: 1252 GEKGEPGEAGN----PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307

Query: 173  PPPPGKPQGPPPQGGKKPQGPP----------PPGKPQGPPPQGDKSRSSQSPPGKPQGP 222
            P P G P  P P G   P G             PG+P  P P G+       PPGK   P
Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG--PPGPPGKRGPP 1365

Query: 223  PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKP--------QGPPAQGGSKSQS 273
               G    QG     G+     P G   P GP  P GKP         GP  + G    +
Sbjct: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1425

Query: 274  ARSPPGKPQGPP-----------QQEGNNPQ-----GPPPPAG-----GNPQQPQAP--- 309
             +  P  P GPP           + E  +P      GPP   G     G P    +P   
Sbjct: 1426 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1485

Query: 310  -------PAGQPQGPPRPPQGGRPSRP 329
                   PAG P GPP PP    P  P
Sbjct: 1486 GDGGIPGPAG-PLGPPGPPGLPGPQGP 1511



 Score =  113 bits (282), Expect = 3e-25
 Identities = 108/328 (32%), Positives = 133/328 (40%), Gaps = 55/328 (16%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
           P ++   P GP+   G    GPP   G P GPP   G++     PPG+P  P   G    
Sbjct: 436 PGMLVEGPPGPAGPAGI--MGPPGLQG-PTGPPGDPGDRG----PPGRPGLPGADG---- 484

Query: 89  SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNRPQGPPPP-GKPQGPPPQG 145
            P  P      P   GG+  +GP     + Q      Q     +GPP P G    P P G
Sbjct: 485 LPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVG 544

Query: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGKKPQGPPPPGKPQGPP 203
               S     G+   P PQG    QGPP P GKP  +G P   G +       G P  P 
Sbjct: 545 GPGSS--GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR-------GMPGEPG 595

Query: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK-----------PQGPPPQGGNK-- 250
            +GD  R     PG P     +G   PQGPP PPG            P+G P + G +  
Sbjct: 596 AKGD--RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 653

Query: 251 --PQGPP-PPGKP-----QGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAGG 301
             P+G P  PG+P      GPP   G+       P G+P GPP Q+GN  PQG P P G 
Sbjct: 654 LGPRGTPGAPGQPGMAGVDGPPGPKGN-----MGPQGEP-GPPGQQGNPGPQGLPGPQGP 707

Query: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
                +  P G+P     P   G P  P
Sbjct: 708 IGPPGEKGPQGKPGLAGLPGADGPPGHP 735



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 60/170 (35%), Positives = 64/170 (37%), Gaps = 31/170 (18%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKP--------------QGPPPQGGNKPQGPPPPGKPQG 79
            G      P G   P GP  P GKP              QG P   G    GPP P  P G
Sbjct: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ--DGPPGPMGPPG 1438

Query: 80   -PPPQGDK-SRSPRSPPGKPQ--GPP-PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP-P 133
             P  +GD  S+  +  PG     GPP  QG    +G P   G P      G   P GP  
Sbjct: 1439 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1498

Query: 134  PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
            PPG P  P PQG        P G      P G     G P PPG P GPP
Sbjct: 1499 PPGPPGLPGPQG--------PKGNKGSTGPAGQKGDSGLPGPPGSP-GPP 1539



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 26/102 (25%)

Query: 239 KPQGPPPQGGNKPQGPPPPGKPQ---------GPPAQGGSKSQSARSPPGK-PQGPPQQE 288
           KP  PP    N+  GP  P +           G   + G K + A   PG   +GPP   
Sbjct: 392 KPTSPP----NEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPA 447

Query: 289 G----------NNPQGPPPPAG--GNPQQPQAPPAGQPQGPP 318
           G            P GPP   G  G P +P  P A    GPP
Sbjct: 448 GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  145 bits (366), Expect = 5e-35
 Identities = 111/349 (31%), Positives = 140/349 (40%), Gaps = 62/349 (17%)

Query: 34   GNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPPQGDKSRS 89
            G P  PS +G   P    PP P G P  P P+G   P    PP    G   PP      +
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 90   PRSPPGKPQG----PPPQGGNQPQG--PPPPPGKPQGPPPQGGNR--------PQG---- 131
            P + P  P+G    PPP+G        PP P G    PPP+G           P+G    
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 132  PPPPGKPQGP------PPQGDKSRSPRSPPGKPQGPPP--QGG---NQPQG--------P 172
            P P G P  P      P  G  + SP+  P  P   PP  +GG     P+G        P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 173  PPPPGKPQGPPPQGGKKPQGPPPPGKPQG---PPPQGDKSRSSQSPPGKPQGP---PPQG 226
            P P G P  PPP+G   P    PP    G   PP +G  + +  +PP    GP   PP+G
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308

Query: 227  GNQPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--------PPAQGGSKSQSARS 276
               P    PP P G P  PPP+G   P    PP  P+G        P ++GG  + S++ 
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP-SPKGTPTLPATTPSSKGGPTTPSSKE 1367

Query: 277  PPGKPQGPPQQEGNNPQGPPPPAGG----NPQQPQAPPAGQPQGPPRPP 321
             P  P   P  +G     PP P  G    +P+     PA  P  P + P
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416



 Score =  144 bits (362), Expect = 1e-34
 Identities = 111/340 (32%), Positives = 138/340 (40%), Gaps = 45/340 (13%)

Query: 34   GNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQG---D 85
            G P  PSP+G   P    PP P G P  P P+    P    PP   G P  P P+G    
Sbjct: 929  GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988

Query: 86   KSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPP-PQGGNRPQGPPPPGKPQGPP 142
             + +P SP G P  P P+G   P    PP P G P   P P+G + P    PP  P+G P
Sbjct: 989  PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS-PKGSP 1047

Query: 143  -----PQGDKSRSPR---SPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGKKPQG 192
                 P+G  +       SP G P  P  +G   P    PP P G P  P P+G   P  
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107

Query: 193  PPPPGKPQG---PPPQGDKSRSSQSPPGKPQG---PPPQGGNQPQG--PPPPPGKPQGPP 244
              PP    G   PP +G  +  + +PP    G   PPP+G        PP P G    PP
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167

Query: 245  PQGGNKPQGPPPPGKPQG--PPAQGGSKSQSARSPPGKPQG----PPQQEGNNPQGPPP- 297
            P+G        PP    G   P+  G+ +  A +PP    G     P+     P   PP 
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227

Query: 298  PAGG----NPQQPQAPPAGQPQ----GPPRPPQGGRPSRP 329
            P GG    +P+     PA  P     GP  PP  G P+ P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267



 Score =  142 bits (357), Expect = 5e-34
 Identities = 109/335 (32%), Positives = 138/335 (41%), Gaps = 42/335 (12%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQG--PPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPP 82
            +P    G P  PSP+    P    PP P G P  P P+G   P    PP   G P  P P
Sbjct: 946  TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 83   QGDKSR---SPRSPPGKPQGPP-PQGGNQPQG--PPPPPGKPQGPP-PQGGNRPQG---P 132
            +G  +    +P SP G P   P P+G + P    PP P G P   P P+G         P
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065

Query: 133  PPPGKPQGPPPQG---DKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGG 187
             P G P  P  +G     + +P SP G P  P P+G   P    PP P G    PP +G 
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125

Query: 188  KKPQGPPPPGKPQG---PPPQGDKSRSSQSPPGKPQG---PPPQGGNQPQGPPPPPGKPQ 241
                   PP    G   PPP+G  +  + +PP    G   PPP+G      P  P   P 
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG-----APTTPAATP- 1179

Query: 242  GPPPQGG---NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG-PPQQEGN----NPQ 293
             P P+GG     P+G P       P  +GG  + S +  P  P   PP  +G     +P+
Sbjct: 1180 -PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238

Query: 294  GPPPPAGGNPQQPQAPPA-GQPQGPPRPPQGGRPS 327
            G P      P  P+  PA   P+G P PP    PS
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273



 Score =  139 bits (349), Expect = 5e-33
 Identities = 110/346 (31%), Positives = 136/346 (39%), Gaps = 45/346 (13%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQG--PPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPP--- 81
            +P    G P  PSP+G   P    PP P G P   P P+G + P    PP  P+G P   
Sbjct: 992  TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS-PKGSPAAT 1050

Query: 82   --PQGDKSRSPR---SPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNRPQGPPP 134
              P+G  +       SP G P  P  +G   P    PP P G P  P P+G   P    P
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110

Query: 135  PGKPQG--PPPQGDKSRSPRSPPGKPQG----PPPQGGNQPQG--PPPPPGKPQGPPPQG 186
            P    G   PP      +P + P  P+G    PPP+G        PP P G    PPP+G
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170

Query: 187  GKKPQGPPPPGKPQG---PPPQGDKSRSSQSPPGKPQG---PPPQGGNQPQG--PPPPPG 238
                    PP    G   P P+G  +  + +PP    G   P P+G        PP P G
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 239  KPQGPPPQGGNKPQGPPPPGKPQGP--PAQGGSKSQSARSPPGKPQG---PPQQEGNNPQ 293
                P P+G        PP    GP  P   G+ +  A +PP    G   PP +   NP 
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290

Query: 294  --GPPPPAGG----NPQQPQAPPAGQPQGPP----RPPQGGRPSRP 329
               PP P GG     P+    PPA  P  P      PP  G P+ P
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336



 Score =  136 bits (342), Expect = 3e-32
 Identities = 109/341 (31%), Positives = 136/341 (39%), Gaps = 47/341 (13%)

Query: 35   NPQGPSPQGGNKPQGPPP--PPG----KPQGPPPQGGNKP---QGPPPPGKPQGPP---- 81
            +P  PSP+G   P    P  P G      + P P   N P   +GP  P   Q P     
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 82   -PQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNRPQGPPPP--- 135
                 K+R+  +P G P  P P+G   P    PP P G P  P P+    P    PP   
Sbjct: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK 974

Query: 136  GKPQGPPPQG---DKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPP-PQGGKK 189
            G P  P P+G     + +P SP G P  P P+G   P    PP P G P   P P+G   
Sbjct: 975  GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034

Query: 190  PQGPPPPGKPQGPP-----PQGDKSRSSQ---SPPGKPQGPPPQGGNQPQG--PPPPPGK 239
            P    PP  P+G P     P+G  +  +    SP G P  P  +G   P    PP P G 
Sbjct: 1035 PPAATPPS-PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093

Query: 240  PQGPPPQGGNKPQGPPPPGKPQG--PPAQGGSKSQSARSPPGKPQG----PPQQEGNNPQ 293
            P  P P+G   P    PP    G   P   G+ +  A +PP    G    PP+     P 
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153

Query: 294  GPPPPAGGNPQQPQAPPAGQPQGP---PRPPQGGRPSRPPQ 331
              PP   G    P  PP G P  P   P  P+GG  +  P+
Sbjct: 1154 ATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGLATPSPK 1192



 Score =  128 bits (322), Expect = 6e-30
 Identities = 105/333 (31%), Positives = 131/333 (39%), Gaps = 43/333 (12%)

Query: 28   SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP---PPQGGNKPQGPPPPGKPQGP---- 80
            +P+  A  P  PSP+GG      PPP G P  P   PP        P P G P  P    
Sbjct: 1148 APTTPAATP--PSPKGG---LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202

Query: 81   --PPQGDKSRSPRSPPGKPQG--PPPQGG---NQPQG--------PPPPPGKPQGPPPQG 125
              P  G  + SP+  P  P    P P+GG     P+G        PP P G P  PPP+G
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262

Query: 126  GNRPQGPPPPGKPQG---PPPQGDKSR---SPRSPPGKPQGPPPQGGNQPQG--PPPPPG 177
               P    PP    G   PP +G  +    +P SP G P   PP+G   P    PP P G
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322

Query: 178  KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
             P  PPP+G   P    PP  P+G P     + SS+  P  P     +G   P   P   
Sbjct: 1323 SPGTPPPKGAPTPPAVTPP-SPKGTPTLPATTPSSKGGPTTPSS--KEGPTPPAATPSHK 1379

Query: 238  GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 297
            G P   PP     P  P P G P  P     S  ++  +P  +       +G+      P
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD----LTP 1435

Query: 298  PAGGNPQQPQAPPAGQPQGPPRPPQG-GRPSRP 329
            PA       +AP    P+G P  P   G P+ P
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468



 Score =  127 bits (319), Expect = 1e-29
 Identities = 106/338 (31%), Positives = 131/338 (38%), Gaps = 49/338 (14%)

Query: 39   PSPQGGNKP---QGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQG---DKSR 88
            P+P   N P   +GP  P  K         + P+     P P G P  P P+G     + 
Sbjct: 886  PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA 945

Query: 89   SPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNRPQG---PPPPGKPQGPPP 143
            +P SP G P  P P+    P    PP P G P  P P+G   P     P P G P  P P
Sbjct: 946  TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 144  QG---DKSRSPRSPPGKPQGPP-PQGGNQPQG--PPPPPGKPQGPP-PQGGKKPQG---P 193
            +G     + +P SP G P   P P+G + P    PP P G P   P P+G         P
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065

Query: 194  PPPGKPQGPPPQGDKSRSSQSPP---GKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGG 248
             P G P  P  +G  +  + +PP   G P  P P+G   P    PP P G    PP +G 
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125

Query: 249  --------NKPQG----PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP- 295
                      P+G    PPP G P  P A   S      +PP  P+G P      P  P 
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPK 1183

Query: 296  ----PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
                 P   G P  P A P     G   P   G P+ P
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221



 Score =  127 bits (318), Expect = 2e-29
 Identities = 104/344 (30%), Positives = 128/344 (37%), Gaps = 67/344 (19%)

Query: 52   PPPGKPQGPP---------PQGGNKP----------------QGPPPPGKPQGP-----P 81
            P P  P+G P         P+G   P                +GP  P   Q P      
Sbjct: 856  PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 82   PQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNRPQG---PPPPG 136
                K+R+  +P G P  P P+G   P    PP P G P  P P+    P     P P G
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 137  KPQGPPPQG---DKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPP-PQGGKKP 190
             P  P P+G     + +P SP G P  P P+G   P    PP P G P   P P+G   P
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035

Query: 191  QGPPPPGKPQGPP-----PQG---DKSRSSQSPPGKPQGPPPQGGNQPQG--PPPPPGKP 240
                PP  P+G P     P+G     + +  SP G P  P  +G   P    PP P G P
Sbjct: 1036 PAATPP-SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094

Query: 241  QGPPPQGGNKPQGPPPPGKPQG---PPAQGGSKSQSARSPPGK-------PQGPPQQEGN 290
              P P+G   P    PP    G   PP +G   + +A  P  K       P+G P     
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154

Query: 291  NPQGP-----PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
             P  P      PP  G P  P A P     G   P   G P+ P
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198



 Score =  119 bits (298), Expect = 4e-27
 Identities = 98/326 (30%), Positives = 122/326 (37%), Gaps = 44/326 (13%)

Query: 39   PSPQGGN-KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97
            PSP G +  PQ   PP  K    P         P  P +    P      +  +  P   
Sbjct: 794  PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853

Query: 98   QGPPPQGGNQPQGPPPP----PGKPQG--------PPPQGGNRP---QGPPPPGKPQGPP 142
              P P     P+G P P    P  P+G        P P   N P   +GP  P   Q P 
Sbjct: 854  HSPTPPS---PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA 910

Query: 143  -----PQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGKKPQG--- 192
                     K+R+  +P G P  P P+G   P    PP P G P  P P+    P     
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP 970

Query: 193  PPPPGKPQGPPPQGDKSRSSQSPP---GKPQGPPPQGGNQPQG--PPPPPGKPQGPP-PQ 246
            P P G P  P P+G  +  + +PP   G P  P P+G   P    PP P G P   P P+
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030

Query: 247  GGNKPQG---PPPPGKPQGPPAQGGSKSQSARSPPGKPQGP--PQQEGNNPQGPPPPAGG 301
            G + P     P P G P   P   G+ +  A + P    GP  P  +G     P PPA  
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG----APTPPAAT 1086

Query: 302  NPQQPQAPPAGQPQGPPRPPQGGRPS 327
             P     P    P+G P PP    PS
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPS 1112



 Score =  109 bits (272), Expect = 4e-24
 Identities = 112/437 (25%), Positives = 146/437 (33%), Gaps = 138/437 (31%)

Query: 24   SQEESPSLIAGNPQGPSPQGG---NKPQG--------PPPPPGKPQGPPPQGGNKPQGPP 72
            S + +P+  A  P  PSP+GG     P+G        PP P G P  PPP+G   P    
Sbjct: 1213 SPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270

Query: 73   PPGKPQG---PPPQGDKSRS---PRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQ 124
            PP    G   PP +G  + +   P SP G P   PP+G   P    PP P G P  PPP+
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330

Query: 125  GGNRPQG---PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 181
            G   P     P P G P  P         P +P  K +GP P     P   P   G P  
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK-EGPTP-----PAATPSHKGGPAM 1384

Query: 182  PPPQGGKKPQGPPPPGKPQGP----------------------PPQGD------------ 207
             PP   + P  P P G P  P                      P +GD            
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444

Query: 208  KSRSSQSPPGKPQGPPPQGG-NQPQGPPPPPGKPQGPPPQGGNK----------PQGPPP 256
            K+ ++ +P G P  P  +G    P   PP P +P  P     +           P G P 
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504

Query: 257  -----PGKPQGPPAQGGS-------------------------------------KSQSA 274
                 P  P+  PA   S                                     K+ + 
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564

Query: 275  RSPPGKPQGPPQQEGNNPQG-----------------PPPPAGGNPQQPQAPPAGQP--- 314
             +P   P  P  +E ++P                   PP     +P++   PPA  P   
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624

Query: 315  -QGPPRPPQGGRPSRPP 330
             +GP  P   G P+ PP
Sbjct: 1625 EKGPATPAPKGTPTSPP 1641



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 87/371 (23%), Positives = 121/371 (32%), Gaps = 54/371 (14%)

Query: 7    SVALLALSSAQNLNEDVSQEESPSLIAGN--PQGPSPQGGNKPQGPPPPPGKPQGPPPQG 64
            S A++ LS  +     V++E + +   G+  P   +P    K      P G P  P  +G
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 65   GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-- 122
                    PP   + P P+   + S  SP   P  P P G   P  P   P  P+  P  
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSS--SPKKAPATPAPMGA--PTLPAVIPSSPKEVPAT 1519

Query: 123  PQGGNRPQGPP-------------------PPG----KPQGPPPQGDKSRSPRSPPGKPQ 159
            P     P  P                    PP      P+  P       +P +P  K  
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579

Query: 160  GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219
              PP          P P +   PP      P+  P P  P   PP  +K  ++ +P G P
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP--PAVTPPSPEKGPATPAPKGTP 1637

Query: 220  QGPPPQGGNQPQGPPPP-----------PGKPQGPPPQGGNKP-----QGPPPPGKP--Q 261
              PP    +    P  P           P   +G P + G          P P   P   
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697

Query: 262  GPPAQG-GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320
             P  +G  +K  SA SPP  P    +     P     PA   P Q  +    + +     
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757

Query: 321  PQGGRPSRPPQ 331
            P+G  P  PP+
Sbjct: 1758 PKG--PLAPPE 1766



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 85/329 (25%), Positives = 110/329 (33%), Gaps = 62/329 (18%)

Query: 36   PQGPSPQGGNKP--------QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87
            P  PS +  + P        +G P P      P     +  + P PP      PP  +K 
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV---TPPSPEKG 1627

Query: 88   RSPRSPPGKPQGPPPQGGNQPQGPPPP-----------PGKPQGPPPQGG---------- 126
             +  +P G P  PP    +    P  P           P   +G P + G          
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687

Query: 127  NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGP 182
              P+  P    P    PQ  KS S  SP   P  P P   N  +GP     P P  P   
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKS-SATSP---PICPDPSAKNGSKGPLSTVAPAPLLP--V 1741

Query: 183  PPQGGKKPQGPPPPGKPQGP--PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240
                 K  +G      P+GP  PP+   S    +   +   P P+  +    P PP   P
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801

Query: 241  QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP-A 299
              P P        P  P K Q  P+  G   +S    P KP  P  ++   P  PP P +
Sbjct: 1802 LAPSPV-------PTLPPKQQFLPSSPGLVLES----PSKPLAPADEDELLPLIPPEPIS 1850

Query: 300  GGNPQQ------PQAPPAGQPQGPPRPPQ 322
            GG P Q      P    AG P   P   Q
Sbjct: 1851 GGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 76/304 (25%), Positives = 96/304 (31%), Gaps = 53/304 (17%)

Query: 71   PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP- 129
            P P   P  P P+     +P +P  K    PP          P P +   PP      P 
Sbjct: 1556 PSPKKTPAIPTPK----EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611

Query: 130  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK- 188
            + P PP      P +G  + +P+  P  P   P    + P  P     K     PQ  K 
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 189  -----------------KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQP- 230
                              P+  P    P    PQ  KS S+ SPP  P      G   P 
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS-SATSPPICPDPSAKNGSKGPL 1730

Query: 231  ----QGPPPPPGKPQGPPPQG---GNKPQGP--PPPGKPQGPPAQGG-------SKSQSA 274
                  P  P  K      +G    + P+GP  PP  K   P             +S S 
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV 1790

Query: 275  RSPPGKPQGPPQQEGNNPQGPP-----PPAGG----NPQQPQAPPAGQ---PQGPPRPPQ 322
             + P  P   P      P  PP     P + G    +P +P AP       P  PP P  
Sbjct: 1791 SAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850

Query: 323  GGRP 326
            GG P
Sbjct: 1851 GGVP 1854



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 84/377 (22%), Positives = 104/377 (27%), Gaps = 100/377 (26%)

Query: 50  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 109
           P    G P  P   G    + P      Q  P      +S  S P  P  P      +  
Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSL 595

Query: 110 GPPPPPGKPQG--PPPQGGNRP---------QGPPPPG--------------------KP 138
           G P P GKP      P G N            GP   G                     P
Sbjct: 596 GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADP 655

Query: 139 QGPPP-----------------QGDKSRSPRSPPGK-----------------PQGPPPQ 164
            G  P                 +G  S +P++ P K                 P  P PQ
Sbjct: 656 AGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQ 715

Query: 165 -----------GGNQPQGPPPPPGKPQGPPPQGGKKPQG-------PPPPGKPQGPPPQG 206
                          P+  P P   P G PP G KK  G        P    P+  P + 
Sbjct: 716 NTCAPLATLVLAPEIPKSVPSPSLPPAGTPP-GTKKVDGISHTSALAPVASSPKECPTED 774

Query: 207 DKSRSSQSPPGK----PQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 261
             + ++ S  G        P P G +  PQ   PP  K    P         P  P +  
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834

Query: 262 GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA---PPAGQPQ--- 315
             P    S   S  SP       P     +P+G P P+   P  P+    PP   P    
Sbjct: 835 FLPENSLSFQGSKDSPATTHSPTPP----SPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890

Query: 316 -GPPRPPQGGRPSRPPQ 331
              P P +G     P Q
Sbjct: 891 VNLPFPKEGPATPAPKQ 907


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  144 bits (362), Expect = 1e-34
 Identities = 124/363 (34%), Positives = 152/363 (41%), Gaps = 77/363 (21%)

Query: 42   QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKS----RSPRSPPGK 96
            +G   P GPP P G P    P G   P G P    PQGPP P G+K     + P+ P G+
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133

Query: 97   PQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGGNR----PQGPPPPGKPQGP-----P 142
                 P G   P GP  PPG+       G P Q G++     QGPP P  PQGP     P
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193

Query: 143  PQGDKSRSPRSPPGK--------PQG-PPPQGGNQPQGPPPPPGKP--------QGPP-P 184
               D    PR   G         P+G P P G    QG P PPG+          GPP P
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP 1253

Query: 185  QGGKKPQGPPPPGKPQGPP-------PQGDKSRSSQS-PPGKP-QGPPP--------QGG 227
             G + P G P    PQGPP         G+K    ++  PG P +G PP        +G 
Sbjct: 1254 PGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGE 1313

Query: 228  NQPQGPPPPPGKPQGPPPQGGNK--------PQGPPPPGKP-----QGPPAQGGSKSQSA 274
            + P G   PPG P+GPP   G K        P  P PPG+P      GPP   G   +  
Sbjct: 1314 SGPSGAAGPPG-PKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG 1372

Query: 275  RSPPGKPQGPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQP--QGPPRP-----PQGGRP 326
            ++    P G P   G    +GPP PAG   +Q +    G+   +GPP       PQG  P
Sbjct: 1373 QTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGA-P 1431

Query: 327  SRP 329
             +P
Sbjct: 1432 GKP 1434



 Score =  141 bits (356), Expect = 7e-34
 Identities = 132/394 (33%), Positives = 151/394 (38%), Gaps = 104/394 (26%)

Query: 36   PQGPS-PQGGNKPQGPPPPPGK--------------------PQGPP-------PQGGNK 67
            P GP  P G   P+GPP PPGK                    P GPP       P G   
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009

Query: 68   PQG----PPPPGKP--QGPPPQGDKSRSPRSP-----PGKPQGPPP-------------- 102
            P G    P PPG P  QG P    K  +   P     PGK  GPP               
Sbjct: 1010 PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK-DGPPGLRGFPGDRGLPGPV 1068

Query: 103  -----QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQGDKS----RSPR 152
                 +G   P GPP P G P    P G   P G P    PQGPP P G+K     + P+
Sbjct: 1069 GALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQ 1128

Query: 153  SPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGGKK----PQGPPPPGKPQGP- 202
             P G+     P G   P GP  PPG+       G P Q G K     QGPP P  PQGP 
Sbjct: 1129 GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPI 1188

Query: 203  ------------PPQGDKSRSSQSPPGKPQG-PPPQGGNQPQGPPPPPGKP--------Q 241
                         P+G +    Q     P+G P P G    QG P PPG+          
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248

Query: 242  GPP-PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP--QGPPQQEGNNPQGPPPP 298
            GPP P G   P G P    PQGPP  GG  +  A    G+P   G P   G    GPP P
Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPP--GGIGNPGAVGEKGEPGEAGEPGLPGEG--GPPGP 1304

Query: 299  AGGNPQQPQAPPAGQ--PQGPPRPPQGGRPSRPP 330
             G   ++ ++ P+G   P GP  PP    P   P
Sbjct: 1305 KGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSP 1338



 Score =  138 bits (348), Expect = 6e-33
 Identities = 122/351 (34%), Positives = 142/351 (40%), Gaps = 72/351 (20%)

Query: 36   PQGPS-------PQGGNKPQGPPPPPGKPQ-----GPPPQGGNK----PQGPPPPGKPQG 79
            PQGP+       P G   P GP  PPG+       G P Q G+K     QGPP P  PQG
Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQG 1186

Query: 80   P-----PPQGDKSRSPRSPPG--------KPQG-PPPQGGNQPQGPPPPPGKPQGPPPQG 125
            P     P   D    PR   G         P+G P P G    QG P PPG+       G
Sbjct: 1187 PIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVG 1246

Query: 126  GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP-QGPPP 184
               P GPP P  P G P     +  P+ PPG    P   G     G    PG P +G PP
Sbjct: 1247 QMGPPGPPGPRGPSGAP----GADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPP 1302

Query: 185  -----QGGKKPQGPPPPGKPQGP--PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
                 +G K   GP     P GP  PP  D  + S  P G P  P P G   P G   PP
Sbjct: 1303 GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPP 1362

Query: 238  GK--------------PQGPP-PQGGNKPQGPPPPGKPQGPPAQGGSKSQSA-RSPPGK- 280
            G               P G P P G    +GPP P  P+G   + G+K ++    PPGK 
Sbjct: 1363 GDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKT 1422

Query: 281  ----PQGPPQQEG-NNPQGPPPPAG-----GNPQQPQAPPAGQPQGPPRPP 321
                PQG P + G +  +G P P G     G+P  P  PP   P GPP  P
Sbjct: 1423 GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP-GPDGPPG--PMGPPGLP 1470



 Score =  137 bits (346), Expect = 1e-32
 Identities = 122/333 (36%), Positives = 140/333 (42%), Gaps = 49/333 (14%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKSRSPRS 92
            G P  P   G   P+G    PG P     +GG    G P P   +GP  P+G+  R PR 
Sbjct: 868  GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE--RGPRG 925

Query: 93   PPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNRPQGPP-PPGKPQGPPPQGDKSRS 150
              GKP      GG+ P GPP   G P GP  P G   P+GPP PPGK   P   G +  +
Sbjct: 926  ITGKPGPKGNSGGDGPAGPPGERG-PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 151  -------PRSPPGK--PQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGKKPQ--GPPP 195
                   P  PPG   PQGP     P G     GPP PPG+ QG P   GK+     P P
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGE-QGLPGLAGKEGTKGDPGP 1043

Query: 196  PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGP 254
             G P    P G +          P G     GN+ P GPP P G P    P G   P G 
Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI 1103

Query: 255  PPPGKPQGPPAQGGSKSQSARSPPGK--PQGPPQQEG-NNPQGPPPPAG----------- 300
            P    PQGPP   G K       PG+  PQGP  ++G   P G P PAG           
Sbjct: 1104 PGRPGPQGPPGPAGEK-----GAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDK 1158

Query: 301  ---GNPQQPQAPPAGQPQGPPRP--PQG--GRP 326
               G P Q  +      QGPP P  PQG  G+P
Sbjct: 1159 GEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQP 1191



 Score =  137 bits (344), Expect = 2e-32
 Identities = 121/353 (34%), Positives = 138/353 (39%), Gaps = 57/353 (16%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPP---------PPGKPQGPPPQGGNKPQGPP-PPG 75
            E  P  I G P      GG+ P GPP          P G P          P+GPP PPG
Sbjct: 920  ERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFP---------GPKGPPGPPG 970

Query: 76   KPQGPPPQGDKSRS-------PRSPPG--KPQGPP----PQGGNQPQGPPPPPGKPQGPP 122
            K   P   G +  +       P  PPG   PQGP     P G     GPP PPG+   P 
Sbjct: 971  KDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPG 1030

Query: 123  PQGGNRPQGPP-PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
              G    +G P P G P    P G +     R  PG       +G   P GPP P G P 
Sbjct: 1031 LAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPG 1090

Query: 181  GPPPQGGKKPQGPPPPGKPQGPP-PQGDK----SRSSQSPPGKPQGPPPQGGNQPQGPPP 235
               P G   P G P    PQGPP P G+K     +  Q P G+     P G   P GP  
Sbjct: 1091 ERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG 1150

Query: 236  PPGKPQ-----GPPPQGGNK----PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
            PPG+       G P Q G+K     QGPP P  PQGP  Q G         P   QG   
Sbjct: 1151 PPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFG 1210

Query: 287  QEGN-NPQGPPPPAGGNPQQPQAPPAGQ--------PQGPPRPPQGGRPSRPP 330
            Q+G+  P+G P P G    Q    P G+          GPP PP    PS  P
Sbjct: 1211 QKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAP 1263



 Score =  135 bits (341), Expect = 4e-32
 Identities = 121/352 (34%), Positives = 141/352 (40%), Gaps = 83/352 (23%)

Query: 36   PQGPSPQGGNKPQ-GPPPPPGKPQGPP-PQGGNKPQGPP-------------------PP 74
            P G   + G+  Q GPP PPG P+GP    G + PQGPP                    P
Sbjct: 1235 PPGEKGETGDVGQMGPPGPPG-PRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEP 1293

Query: 75   GKP--QGPP-PQGDKSRSPRSPPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGN 127
            G P   GPP P+G++     S P    GPP    P G + P+G P P G P  P      
Sbjct: 1294 GLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP------ 1347

Query: 128  RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP---PPPGKPQGPPP 184
             P G P P    GPP  GDK       PG+   P P G   P GPP    PPG P GP  
Sbjct: 1348 GPPGEPGPAGQDGPP--GDKGDD--GEPGQTGSPGPTGEPGPSGPPGKRGPPG-PAGPEG 1402

Query: 185  QGGKK----------PQGPPPPGKPQGPP--PQGDKSRSSQSPPGKPQGPPPQGGNQPQG 232
            + G+K          P G   P  PQG P  P  D  R    P G+ QG P  G   P G
Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGE-QGLP--GSPGPDG 1459

Query: 233  PPPPPGKPQGPPPQGGNKPQGPP----------PPGKP--------QGPPAQGGSKSQSA 274
            PP P G P  P  +G + P+G            PPG+          GP    G K +  
Sbjct: 1460 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQG 1519

Query: 275  RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ-----PQGPPRPP 321
             + P  P GPP   G    GPP P G         P G+     P GPP PP
Sbjct: 1520 ITGPSGPIGPPGPPG--LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569



 Score =  134 bits (337), Expect = 1e-31
 Identities = 119/345 (34%), Positives = 141/345 (40%), Gaps = 56/345 (16%)

Query: 22   DVSQEESPSLIAGNPQGPS-PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQG 79
            DV Q   P      P+GPS   G + PQGPP   G P     +G     G P  PG+   
Sbjct: 1244 DVGQMGPPG--PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGP 1301

Query: 80   PPPQGDKSRSPRSPPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135
            P P+G++     S P    GPP    P G + P+G P P G P  P P G       P P
Sbjct: 1302 PGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG------EPGP 1355

Query: 136  GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP- 194
                GPP  GDK       PG+   P P G   P GPP   G P    P+G +  +G   
Sbjct: 1356 AGQDGPP--GDKGDD--GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKG 1411

Query: 195  ------PPGK-----PQGPP--PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241
                  PPGK     PQG P  P  D  R    P G+ QG P   G  P GPP P G P 
Sbjct: 1412 EAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGE-QGLPGSPG--PDGPPGPMGPPG 1468

Query: 242  GPPPQGGNKPQGPPPPGKPQ-----GPPAQGGSKSQSARSPPGKPQGPPQQEG----NNP 292
             P  +G + P+G    G P      GPP + G K       P    GP  ++G    + P
Sbjct: 1469 LPGLKGDSGPKGEK--GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP 1526

Query: 293  QGPPPPAG--GNPQQPQAPPAGQPQGP------PRPPQGGRPSRP 329
             GPP P G  G P    A  +  P GP      P PP  G P  P
Sbjct: 1527 IGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPP--GPPGPP 1569



 Score =  131 bits (329), Expect = 1e-30
 Identities = 100/282 (35%), Positives = 115/282 (40%), Gaps = 31/282 (10%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85
            E  PS  AG P    P G + P+G P P G P  P       P G P P    GPP  GD
Sbjct: 1313 ESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP------GPPGEPGPAGQDGPP--GD 1364

Query: 86   KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQG 145
            K       PG+   P P G   P GPP   G P    P+G    +G       +GPP + 
Sbjct: 1365 KGDD--GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGK- 1421

Query: 146  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP-PGKPQGPPP 204
                 P  P G P  P P G     GP    G P  P P G   P GPP  PG      P
Sbjct: 1422 ---TGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP 1478

Query: 205  QGDKSRSSQ----SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGK 259
            +G+K          PPG+      +G   PQG   P G+     P G   P GPP PPG 
Sbjct: 1479 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG---PIGPPGPPGL 1535

Query: 260  PQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAG 300
            P GPP   G+K  S       P GP  + G+  P GPP P G
Sbjct: 1536 P-GPPGPKGAKGSSG------PTGPKGEAGHPGPPGPPGPPG 1570



 Score =  130 bits (328), Expect = 1e-30
 Identities = 123/369 (33%), Positives = 146/369 (39%), Gaps = 89/369 (24%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGK--PQGPP--PQ 83
            P  + G    P P+G   PQG P PPG+   P  QG   PQG   PPG+  P G P  P 
Sbjct: 695  PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPG 754

Query: 84   GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ------------------------ 119
               +  P   PGK   P  +GG  P GP  P G P                         
Sbjct: 755  MPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDG 814

Query: 120  -----------------GPP-PQGGNRPQGPPPPGKPQGPP----PQGDKSRSPRSPPGK 157
                             GPP P+G + P+GP   G P G P    P G+K +     PG 
Sbjct: 815  FPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL--GVPGL 872

Query: 158  PQGPPPQGGNQPQGPPPPPGK---------PQGPPPQGGKKPQGPPPPGKPQG----PPP 204
            P  P  QG     G P  PG          P  P P+G + P GP     P+G    P P
Sbjct: 873  PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932

Query: 205  QGDKSRSSQS-PPGK--PQGPP-PQGGNQPQGPPPPPGKP--QGPPPQGGNK-------P 251
            +G+      + PPG+  P GP  P G   P+GPP PPGK    G P Q G         P
Sbjct: 933  KGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 992

Query: 252  QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 311
             GPP    PQGP  + G   +  R  PG P GPP +     QG P  AG    +    PA
Sbjct: 993  PGPPGVVGPQGPTGETGPMGE--RGHPG-PPGPPGE-----QGLPGLAGKEGTKGDPGPA 1044

Query: 312  GQP--QGPP 318
            G P   GPP
Sbjct: 1045 GLPGKDGPP 1053



 Score =  130 bits (328), Expect = 1e-30
 Identities = 120/315 (38%), Positives = 142/315 (45%), Gaps = 50/315 (15%)

Query: 49   GPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 106
            GPP P G+  P+GP  +GG  P G P P    GPP  G+K +     PG P  P  QG  
Sbjct: 832  GPPGPRGEDGPEGPKGRGG--PNGDPGP---LGPP--GEKGKL--GVPGLPGYPGRQG-- 880

Query: 107  QPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQG 165
             P+G    PG P     +GG    G P P   +GP  P+G+  R PR   GKP      G
Sbjct: 881  -PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE--RGPRGITGKPGPKGNSG 937

Query: 166  GNQPQGPPPPPGKPQGPP-PQGGKKPQGPP-PPGK---PQGPPPQGDKS-RSSQSPPGKP 219
            G+ P GPP   G P GP  P G   P+GPP PPGK   P  P  +G+   +    PPG P
Sbjct: 938  GDGPAGPPGERG-PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPP 996

Query: 220  -----QGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKP--QGPPAQG 267
                 QGP     P G     GPP PPG+   P   G    +G P P G P   GPP   
Sbjct: 997  GVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLR 1056

Query: 268  GSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQ--------PQGPP 318
            G      R  PG P G    +GN  P GPP PAG   ++  A  AG         PQGPP
Sbjct: 1057 GFPGD--RGLPG-PVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPP 1113

Query: 319  RP--PQGGRPSRPPQ 331
             P   +G    + PQ
Sbjct: 1114 GPAGEKGAPGEKGPQ 1128



 Score =  125 bits (314), Expect = 5e-29
 Identities = 103/291 (35%), Positives = 119/291 (40%), Gaps = 40/291 (13%)

Query: 34   GNPQGPSPQGGNK----PQGPPPPPGKPQGPPPQGGNK--------PQGPPPPGKPQGPP 81
            G P GP  + G K    P G   PPG P+GPP   G K        P  P PPG+P GP 
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPG-PKGPPGDDGPKGSPGPVGFPGDPGPPGEP-GPA 1356

Query: 82   ----PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGK 137
                P GDK       PG+   P P G   P GPP   G P    P+G    +G      
Sbjct: 1357 GQDGPPGDKGDD--GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAG 1414

Query: 138  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP-P 196
             +GPP +      P  P G P  P P G     GP    G P  P P G   P GPP  P
Sbjct: 1415 LEGPPGK----TGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLP 1470

Query: 197  GKPQGPPPQGDKSRSSQ----SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
            G      P+G+K          PPG+      +G   PQG   P G+     P G   P 
Sbjct: 1471 GLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG---PI 1527

Query: 253  GPP-PPGKPQGPPAQGGSKSQSARS-PPGK-----PQGPPQQEGNNPQGPP 296
            GPP PPG P GPP   G+K  S  + P G+     P GPP   G   Q  P
Sbjct: 1528 GPPGPPGLP-GPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577



 Score =  120 bits (300), Expect = 2e-27
 Identities = 114/339 (33%), Positives = 138/339 (40%), Gaps = 53/339 (15%)

Query: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKP----- 77
           Q+  P++I        P G   P G P PPG   GP  Q G+  +  PP  PG P     
Sbjct: 454 QKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGT-MGPTGQVGDPGERGPPGRPGLPGADGL 512

Query: 78  QGPP--------------PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-----P 118
            GPP                G K     +   + Q    Q     +GP  P G      P
Sbjct: 513 PGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP 572

Query: 119 QGPPPQGGNRPQ----GPPPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 173
            GPP  GG + +    GP  P   QGPP P G   R  R+     +G P Q G  P+G  
Sbjct: 573 VGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTG--PKGDR 630

Query: 174 PPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQ-SPPGKPQGPPPQGGNQPQ 231
              G    P   G K  +G P P  P GPP   G++    +  P G P  P P+G   P+
Sbjct: 631 GFDGLAGLP---GEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPK 687

Query: 232 GPPPPPGKP------QGPPPQGGNKPQGPP-PPGKPQGPPAQGGSKSQSARSPPGK--PQ 282
           GPP PPG P        P P+G   PQG P PPG+   P AQG    Q A  PPG+  P 
Sbjct: 688 GPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPL 747

Query: 283 GPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320
           G P   G     GPP    G+P +   P     QGPP P
Sbjct: 748 GKPGLPGMPGADGPP----GHPGKEGPPGEKGGQGPPGP 782



 Score =  113 bits (282), Expect = 3e-25
 Identities = 100/303 (33%), Positives = 122/303 (40%), Gaps = 40/303 (13%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-------QG 84
           + G P    PQG    QGPP P GKP      G +  +G P    P+G           G
Sbjct: 581 LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640

Query: 85  DKSRSPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
           +K       P  P GPP   G +   G   P G P  P P+G   P+GPP      GPP 
Sbjct: 641 EKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP------GPP- 693

Query: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
                  P    G    P P+G   PQG P PPG+   P  QG   PQG   P   +GP 
Sbjct: 694 ------GPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP- 746

Query: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQG 262
                       PG P    P G    +GPP   G  QGPP PQG   P G P P   +G
Sbjct: 747 ------LGKPGLPGMPGADGPPGHPGKEGPPGEKG-GQGPPGPQG---PIGYPGPRGVKG 796

Query: 263 PPAQGGSK-SQSARSPPGKP--QGPPQQEGNNPQ-GPPPPAG-GNPQQPQAPPAGQPQGP 317
                G K ++  +   G P  +G    +G+  + GPP P G   P+ P+    G P G 
Sbjct: 797 ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG--RGGPNGD 854

Query: 318 PRP 320
           P P
Sbjct: 855 PGP 857



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/165 (28%), Positives = 58/165 (35%), Gaps = 36/165 (21%)

Query: 185 QGGKKPQGPPPPGK-PQGPPPQGDKSRSSQSPPGKPQGPPPQGG--------NQPQGPPP 235
           +G + P  P  PG   + P    D S SS   P   +G     G        N  +    
Sbjct: 359 EGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYD 418

Query: 236 PPGKPQGPPPQGGNKPQGPPPPGKPQ----------GPPAQGGSKSQSARSPPGKP-QGP 284
           P   P   P + G        PG P           GP  + G K + A   PG   +GP
Sbjct: 419 PYYDPTSSPSEIG--------PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGP 470

Query: 285 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           P  EG  P G P P G      Q    G+ +GPP     GRP  P
Sbjct: 471 PGPEG--PAGLPGPPGTMGPTGQVGDPGE-RGPP-----GRPGLP 507



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 14   SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK-PQGPP 72
            SS     + ++    P    G P  P P G   P+G     G P GP  + G+  P GPP
Sbjct: 1511 SSGPKGEQGITGPSGPIGPPGPPGLPGPPG---PKGAKGSSG-PTGPKGEAGHPGPPGPP 1566

Query: 73   -PPGKPQGP-PPQGDKSR 88
             PPG+   P P Q  ++R
Sbjct: 1567 GPPGEVIQPLPIQASRTR 1584


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  144 bits (362), Expect = 1e-34
 Identities = 125/359 (34%), Positives = 141/359 (39%), Gaps = 71/359 (19%)

Query: 33  AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG-GNKPQGPPPPGKPQGPPPQGDKSR--- 88
           AG    P P G     G P   G P GP  +G    P GP   GKP  P  QG+  R   
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGP 565

Query: 89  ----SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGK-----PQ 139
                PR  PG    P P+G +   G     G P GP PQG        PPGK     PQ
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG--------PPGKNGETGPQ 617

Query: 140 GPP----PQGDKSRSPRSPPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191
           GPP    P GDK  +    P   QG P    P G N   G P P G    P   GGK   
Sbjct: 618 GPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDA 677

Query: 192 GPP----PPGKPQGP-------PPQGDKSRSSQSPPGKP--------QGPPPQ-GGNQPQ 231
           G P    PPG    P       PP  +  + +  PPG P        QG P + GG    
Sbjct: 678 GAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSP 737

Query: 232 GPPPPPGKPQGPPPQG---GNKPQGPPPPGKPQGPPAQGGSKSQS-ARSPPG--KPQGPP 285
           GP    G+P GP   G    + P+GP  P  P GP  Q G K +  A   PG   P+G P
Sbjct: 738 GPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP 797

Query: 286 QQEGNNPQGPPPPAG--GNPQQ------------PQAPPAGQPQGPPRPPQGGRPSRPP 330
            + G    GPP PAG  G P Q            P     G P G   PP G  P+ PP
Sbjct: 798 GERGET--GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854



 Score =  136 bits (343), Expect = 2e-32
 Identities = 140/405 (34%), Positives = 156/405 (38%), Gaps = 122/405 (30%)

Query: 34  GNPQGPSPQGG------NKPQGPPPPPGK-----PQGPP-PQG--GNKPQGPPPP--GKP 77
           G P GP PQG         PQGPP P G        GPP PQG  G    G PP   GKP
Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP 656

Query: 78  QGPPPQGDKSRSPRSPPGK-------PQGPP----------------PQGGNQPQGPPPP 114
             P P+GD   +P +P GK        +GPP                P+GG    GPP P
Sbjct: 657 GEPGPKGDAG-APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715

Query: 115 PGKPQGPPPQG--GNRPQ-GPPPP----GKPQGPPPQG----DKSRSPRSPPGKPQGPPP 163
           PG    P  QG  G R   G P P    G+P GP   G    D  R P  P G P GP  
Sbjct: 716 PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP-GPAG 774

Query: 164 QGGNQPQG----------------------PPPPPGKPQGPPPQG-----------GKKP 190
           Q G++ +G                      PP P G P  P   G           G+K 
Sbjct: 775 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG 834

Query: 191 QGPPP-----PGK--PQGPP-PQGDK-SRSSQSPPGKP--------QGPPPQGGNQ-PQG 232
           +G PP     PG   P GPP PQG K  R S   PG           GPP   GN  P G
Sbjct: 835 EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894

Query: 233 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK-SQSARSPPGKP---------- 281
           P   PGK   P P G     G P    P+G   Q G K S  A+ PPG P          
Sbjct: 895 PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG 954

Query: 282 ----QGPPQQEGNNPQGPPPPAG--GNPQQPQAPPAGQPQGPPRP 320
                GPP   G  P+G P P G  G   +P A      +GPP P
Sbjct: 955 ARGLAGPPGMPG--PRGSPGPQGVKGESGKPGANGLSGERGPPGP 997



 Score =  133 bits (335), Expect = 2e-31
 Identities = 123/344 (35%), Positives = 140/344 (40%), Gaps = 58/344 (16%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKSRSPRS 92
           G P    P G N   G   P G+   P P G     G P   G P GP  +G    SP  
Sbjct: 486 GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG-MPGSPGG 544

Query: 93  P--PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG-PPPPGK------PQGPPP 143
           P   GKP  P  QG +   GPP P G    P   G   P+G    PGK      P GP P
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604

Query: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
           QG   ++  + P  P GP   GG++    PP P   QG P  GG     P   GKP  P 
Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGP----PGENGKPGEPG 660

Query: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP-----QGPP-PQGGNKPQGPP-P 256
           P+GD        PG P G    G    +GPP   G P      GPP P+GG    GPP P
Sbjct: 661 PKGD-----AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715

Query: 257 PGKP-----QGPPAQ-GGSKSQSARSPPGKPQGP-----PQQEG----NNPQGPPPPA-- 299
           PG       QG P + GG  S   +   G+P GP     P ++G      P GPP PA  
Sbjct: 716 PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQ 775

Query: 300 ------GGNPQQPQ-APPAGQP-----QGPPRPPQGGRPSRPPQ 331
                 GG P  P  A P G P      GPP P   G P  P Q
Sbjct: 776 PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP--AGFPGAPGQ 817



 Score =  131 bits (329), Expect = 1e-30
 Identities = 130/382 (34%), Positives = 149/382 (39%), Gaps = 81/382 (21%)

Query: 24  SQEESPSLIAGNPQGPSPQGGNK----PQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--- 76
           SQ ES       P GP  Q G      P+G    PGK       GG  PQGPP  GK   
Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP--GKNGE 613

Query: 77  --PQGPP----PQGDKSRSPRSPPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGG 126
             PQGPP    P GDK  +    P   QG P    P G N   G P P G    P   GG
Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673

Query: 127 NRPQGPP----PPGKPQGP-------PPQGDKSRSPRSPPGKP--------QG-PPPQGG 166
               G P    PPG    P       PP  +  +    PPG P        QG P  +GG
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733

Query: 167 NQPQGPPPPPGKPQGPPPQG--GKK-PQGPPPPGKPQGPPPQ-GDKSR-SSQSPPG--KP 219
               GP    G+P GP   G  GK  P+GP  P  P GP  Q GDK    +   PG   P
Sbjct: 734 LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGP 793

Query: 220 QGPPPQGGNQ-PQGPPPPPGKP--------------------QGPP----PQGGNKPQGP 254
           +G P + G   P GP   PG P                     GPP    P GG+ P GP
Sbjct: 794 RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853

Query: 255 PPP-------GKPQGPPAQGGSKSQSARSPPGK--PQGPPQQEGNNPQGPPPPAGGNPQQ 305
           P P       G P GP A G   ++    PPG     GPP   G+  +  PP   GN   
Sbjct: 854 PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913

Query: 306 PQAPPAGQPQGPP-RPPQGGRP 326
           P +P    P+G   +P + G P
Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSP 935



 Score =  130 bits (328), Expect = 1e-30
 Identities = 122/370 (32%), Positives = 137/370 (37%), Gaps = 76/370 (20%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP------------PQGGNKPQGPP- 72
            E  P  +AG P G  P G   PQG     G P GP             P G N   GPP 
Sbjct: 835  EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894

Query: 73   PPGKP--QGPPPQGDKSRSPRSPP-GKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQG 125
            P G P   GPP     + +P SP    P+G    P  +G    QGPP  PG P G     
Sbjct: 895  PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG-PLGIAGIT 953

Query: 126  GNRPQGPPP--PGKPQGPPPQGDKSRS----------PRSPPGKPQGPPPQGGNQPQ--- 170
            G R    PP  PG    P PQG K  S           R PPG PQG P   G   +   
Sbjct: 954  GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG-PQGLPGLAGTAGEPGR 1012

Query: 171  -GPPPPPGKPQGPPPQGGK-------KPQGPPPPGKPQGPPPQGDKSRSS---QSPPGKP 219
             G P   G P      GGK        P  P  PG P  P P G   +S    +S P  P
Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP 1072

Query: 220  QGPPPQGGNQ----PQGP---------------------PPPPGKPQGPPPQGGNKPQGP 254
             G P   G++    PQGP                     P  PG P  P P G     G 
Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132

Query: 255  PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 314
            P P  P+GP    G   +   S    P GPP   GN  +     + G+P QP  PP   P
Sbjct: 1133 PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP-GPPG--P 1189

Query: 315  QGPPRPPQGG 324
             G P P  GG
Sbjct: 1190 PGAPGPCCGG 1199



 Score =  126 bits (317), Expect = 2e-29
 Identities = 131/378 (34%), Positives = 148/378 (39%), Gaps = 79/378 (20%)

Query: 29   PSLIAGNP--QG-PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---- 81
            P   AG P  QG P  +GG    GP    G+P GP   G     GP  P  P GPP    
Sbjct: 715  PPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774

Query: 82   PQGDKSRS----------PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNRP 129
              GDK             PR  PG+     P G     G P   G+P G   +G  G + 
Sbjct: 775  QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG 834

Query: 130  QGPP-----PPG--KPQGPP-PQGDKSR--SPRSP-----PGKPQGPPPQGGNQPQGPPP 174
            +G P     PPG   P GPP PQG K    SP  P     PG    P P G N   GPP 
Sbjct: 835  EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894

Query: 175  PPGKP--QGPP-PQGGKKPQGPPPPGKPQGPPPQ-GDK-SRSSQSPPGKPQGP----PPQ 225
            P G P   GPP P G     G P    P+G   Q G+K S  +Q PPG P GP       
Sbjct: 895  PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP-GPLGIAGIT 953

Query: 226  GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP----------PPGKPQGPPAQGGSKSQSAR 275
            G     GPP  PG    P PQG     G P          PPG PQG P   G+  +  R
Sbjct: 954  GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG-PQGLPGLAGTAGEPGR 1012

Query: 276  --------------SPPGK--------PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313
                          SP GK        P  P       P GP  PAG +  + ++ PAG 
Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG- 1071

Query: 314  PQGPPRPPQGGRPSRPPQ 331
            P G P  P G R +  PQ
Sbjct: 1072 PAGAP-GPAGSRGAPGPQ 1088



 Score =  120 bits (302), Expect = 1e-27
 Identities = 113/353 (32%), Positives = 129/353 (36%), Gaps = 71/353 (20%)

Query: 39  PSPQGGNKPQGPPPPPGKPQGPPPQGGNKP------------QGPPPPGKPQGPP----- 81
           P PQG    QGPP PPG    P  +G   P            +GPP P    G P     
Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430

Query: 82  -----PQGDKS----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNR---- 128
                  G K     R  R   G P  P  +G +   G P  PG   G P   G R    
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG-ANGLPGAAGERGAPG 489

Query: 129 ---PQGP-------PPPGKPQGPPPQGDKSRSPRSPPGK---PQGPPPQGGNQPQGPPPP 175
              P GP        P G+   P P G   R     PG+   P GP  +G     G P  
Sbjct: 490 FRGPAGPNGIPGEKGPAGERGAPGPAG--PRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 176 PGKPQGPPPQGGKKPQGPPPPGKPQGPP-------PQGDKSRSSQSPPGKPQGPPPQGGN 228
            GKP  P  QG     GPP P  P+G P       P+G     +   PGK       GG 
Sbjct: 548 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG-----NDGAPGKNGERGGPGGP 602

Query: 229 QPQGPPPPPGK--PQGPP----PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP- 281
            PQGPP   G+  PQGPP    P G     GPP P   QG P  GG   ++ +  PG+P 
Sbjct: 603 GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK--PGEPG 660

Query: 282 ----QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
                G P   G       P   G P    AP      GPP P  G   + PP
Sbjct: 661 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713



 Score =  113 bits (283), Expect = 2e-25
 Identities = 120/368 (32%), Positives = 145/368 (39%), Gaps = 86/368 (23%)

Query: 27  ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP-----QGPPPQGGNKPQGPPPPG------ 75
           + P+     P G  PQG   P+G P PPG P      G P Q G+ P  P PPG      
Sbjct: 90  QPPTAPTRPPNGQGPQG---PKGDPGPPGIPGRNGDPGIPGQPGS-PGSPGPPGICESCP 145

Query: 76  -KPQGPPPQGDKSR--------------SPRSPPGKPQGPPPQGGNQPQGPPPPPGKP-- 118
             PQ   PQ D                  P  PPG P GPP   G+     P  PG P  
Sbjct: 146 TGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPP-GPPGTSGH-----PGSPGSPGY 199

Query: 119 QGPPPQGGNR-PQGPP-PPGK--PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 174
           QGPP + G   P GPP PPG   P GP  +  +S  P   PG+   P P G   P G P 
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP-GRPGERGLPGPPGIKGPAGIPG 258

Query: 175 PPGKP--QGPPPQGGKKPQGPPP--------PGKPQGPPPQGDKSRSSQ-SPPGKPQGPP 223
            PG    +G   + G+K +   P        PG+   P P G +    +   PG P    
Sbjct: 259 FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAG 318

Query: 224 PQGGN-------QPQGPPPPPGK---PQGPPPQGGNKPQGPP----PPGKPQGPPAQGGS 269
            +G +       QP GPP PPG    P  P  +G   P G P     PG+   P  QG +
Sbjct: 319 ARGNDGARGSDGQP-GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377

Query: 270 KSQSARSPPG-----------KPQGPPQQEG-NNPQGPPPPAGGNPQQPQAPPAGQP--- 314
            +Q    PPG            P G P   G    +GPP PAG N        AG+P   
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437

Query: 315 --QGPPRP 320
             +G P P
Sbjct: 438 GAKGEPGP 445



 Score =  113 bits (283), Expect = 2e-25
 Identities = 120/387 (31%), Positives = 139/387 (35%), Gaps = 96/387 (24%)

Query: 27  ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG--GNKPQGP------------- 71
           + P    G+P  P   G N   G P  PG P  P P G   + P GP             
Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161

Query: 72  -----------PPPGKPQGPPPQGDKSRSPRSPPGKP--QGPPPQGGNQ-PQGPPPPPGK 117
                      P P  P GPP     S  P SP G P  QGPP + G   P GPP PPG 
Sbjct: 162 SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP-GSPGYQGPPGEPGQAGPSGPPGPPGA 220

Query: 118 --PQGPPPQGG--NRP--------QGPP----PPGKPQGPPPQGDKSRSPRSP------- 154
             P GP  + G   RP         GPP    P G P  P  +G +    R+        
Sbjct: 221 IGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGA 280

Query: 155 ---------PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK----------KPQGPPP 195
                    PG+   P P G   P+G P   G+P  P   G +          +P  P P
Sbjct: 281 PGLKGENGLPGENGAPGPMG---PRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP 337

Query: 196 PGKPQGPPPQGDK-------SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
           PG    P   G K       S  S   PG+   P PQG    QGPP PPG    P  +G 
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE 397

Query: 249 NKPQG-PPPPG--KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG--GNP 303
             P G P  PG    +GPP   G     A   PG   G  +   N  +G P P G  G  
Sbjct: 398 MGPAGIPGAPGLMGARGPPGPAG-----ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452

Query: 304 QQPQAPPA----GQPQGPPRPPQGGRP 326
             P  P A    G+   P  P   G P
Sbjct: 453 GIPGVPGAKGEDGKDGSPGEPGANGLP 479



 Score =  109 bits (272), Expect = 4e-24
 Identities = 104/314 (33%), Positives = 126/314 (40%), Gaps = 44/314 (14%)

Query: 36  PQGPS----PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
           PQ P+    P  G  PQGP   PG P G P + G+ P  P  PG P  P P G     P 
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPP-GIPGRNGD-PGIPGQPGSPGSPGPPGICESCPT 146

Query: 92  SPPG-KPQ--------GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142
            P    PQ        G    G     GP  PPG P GPP   G+ P  P  PG  QGPP
Sbjct: 147 GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPG-PPGPPGTSGH-PGSPGSPGY-QGPP 203

Query: 143 PQGDKSRSPRSPPGKPQ--GPP-PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKP 199
            +  ++  P  PPG P   GP  P G +   G P  PG+   P P G K P G   PG P
Sbjct: 204 GEPGQA-GPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG--IPGFP 260

Query: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259
                +G   R+ +       G   + G   +   P P  P+G P + G        PG 
Sbjct: 261 GMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGR-------PGL 313

Query: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEG----------NNPQGPPPPAGGNPQQPQAP 309
           P    A+G   ++ +   PG P GPP   G            P G P   G   Q+ +  
Sbjct: 314 PGAAGARGNDGARGSDGQPG-PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 310 PAGQ--PQGPPRPP 321
           P G    QGPP PP
Sbjct: 373 PQGHAGAQGPPGPP 386



 Score =  102 bits (253), Expect = 6e-22
 Identities = 106/346 (30%), Positives = 120/346 (34%), Gaps = 94/346 (27%)

Query: 39   PSPQGGNKPQGPPPPPGKP--QGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSP--RSP 93
            P P G N   GPP P G P   GPP P G     G P    P+G   Q  +  SP  + P
Sbjct: 881  PGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGP 940

Query: 94   PGKPQGPPP----QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP----------PPGKPQ 139
            PG P GP       G     GPP  PG    P PQG     G P          PPG PQ
Sbjct: 941  PGAP-GPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG-PQ 998

Query: 140  GPP--------PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG----- 186
            G P        P  D +      PG+   P  +G     G P  PG P  P P G     
Sbjct: 999  GLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPA 1058

Query: 187  GKK----------PQGPPPPGKPQGPP----PQGDKSRSSQ----------------SPP 216
            GK           P G P P   +G P    P+GDK  + +                  P
Sbjct: 1059 GKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAP 1118

Query: 217  GKP-----QG----PPPQGGNQPQGPPPPPGK--------PQGPPPQGGNKPQ------- 252
            G P     QG    P P G   P GP  PPGK        P GPP   GN+ +       
Sbjct: 1119 GSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178

Query: 253  ------GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 292
                  GPP P    GP   G   +  A     K  G     G+ P
Sbjct: 1179 GHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEP 1224



 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 108/327 (33%), Positives = 127/327 (38%), Gaps = 82/327 (25%)

Query: 50  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 109
           P  P G+     PQ    P  PP    PQG  P+GD       PPG P      G N   
Sbjct: 77  PEIPFGECCAVCPQPPTAPTRPPNGQGPQG--PKGDP-----GPPGIP------GRNGDP 123

Query: 110 GPPPPPGKPQGPPPQG--GNRPQGP------------------------PPPGKPQGPPP 143
           G P  PG P  P P G   + P GP                        P P  P GPP 
Sbjct: 124 GIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG 183

Query: 144 QGDKSRSPRSPPGKP--QGPPPQGGNQ-PQGPPPPPGK--PQGPPPQGGKKPQGPPPPGK 198
               S  P S PG P  QGPP + G   P GPP PPG   P GP  + G+  + P  PG+
Sbjct: 184 PPGTSGHPGS-PGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGR-PGRPGE 241

Query: 199 PQGPPPQGDKSRSSQSPPGKPQGPPPQG--------GNQPQGPPPP-------PGKPQGP 243
              P P G K      P G P  P  +G        G + +   P        PG+   P
Sbjct: 242 RGLPGPPGIK-----GPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296

Query: 244 PPQGGNKPQGPP-PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG-- 300
            P G   P+G P   G+P  P A G   +  AR   G+P GPP        GPP  AG  
Sbjct: 297 GPMG---PRGAPGERGRPGLPGAAGARGNDGARGSDGQP-GPP--------GPPGTAGFP 344

Query: 301 GNP-QQPQAPPAGQPQGPPRPPQGGRP 326
           G+P  + +  PAG P     P Q G P
Sbjct: 345 GSPGAKGEVGPAGSPGSNGAPGQRGEP 371



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 93/286 (32%), Positives = 103/286 (36%), Gaps = 46/286 (16%)

Query: 77  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136
           P    P G+       PP  P  PP   G  PQGP   PG P G P + G+ P  P  PG
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPP--NGQGPQGPKGDPGPP-GIPGRNGD-PGIPGQPG 130

Query: 137 KPQGPPPQGDKSRSPRSPPG-KPQ--------GPPPQGGNQPQGPPPPPGKPQGPPPQGG 187
            P  P P G     P  P    PQ        G    G     GP  PPG P GPP   G
Sbjct: 131 SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPG-PPGPPGTSG 189

Query: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQ 246
                   PG P  P  QG      Q+ P  P GPP   G + P G     G+P  P  +
Sbjct: 190 H-------PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGER 242

Query: 247 GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNN----------PQGP- 295
           G   P G   P    G P   G +    R+      G P  +G N          P GP 
Sbjct: 243 GLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPR 302

Query: 296 -PPPAGGNPQQPQAPPA----------GQPQGPPRPP-QGGRPSRP 329
             P   G P  P A  A          GQP GPP PP   G P  P
Sbjct: 303 GAPGERGRPGLPGAAGARGNDGARGSDGQP-GPPGPPGTAGFPGSP 347


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score =  144 bits (362), Expect = 1e-34
 Identities = 104/349 (29%), Positives = 130/349 (37%), Gaps = 54/349 (15%)

Query: 26  EESPSLIAGNPQGPSPQGGNKPQGPP--------PPPGKPQGPPPQG-------GNKPQG 70
           EE P L        SP     P  PP        PP   P  P P+           P  
Sbjct: 436 EEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS 495

Query: 71  PPPPGKPQGPPPQGDK-SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP 129
           PPP   P  PPP+    S    SP   P+  PP    +    PPP   P  PP +    P
Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE--ESP 553

Query: 130 QGPPPPGKPQGPPPQGDK-----SRSPRSPPGK--PQGPPPQGG------NQPQGPPPPP 176
             PPP   P  PPP+  +       SP SPP +  P  PPP+         +    PPP 
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613

Query: 177 GKPQGPPPQGGK-------KPQGPPPPGKPQGPPPQGDK-------SRSSQSPPGKPQGP 222
             P  PPP+  +        P  PPP   P  PPP+  +       SR S  P   P  P
Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673

Query: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQ 282
           PP+    P  PPP   +   PPP+  + P  PPP   P  PP +    S      P  P 
Sbjct: 674 PPE--ESPTSPPPEASR-LSPPPE--DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728

Query: 283 GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
             P++    P+   P     P++P   P  +P+ P   PQ   P   PQ
Sbjct: 729 --PEEPQLCPRSEGPHLSPRPEEPHLSP--RPEEPHLSPQAEEPHLSPQ 773



 Score =  133 bits (334), Expect = 3e-31
 Identities = 112/370 (30%), Positives = 137/370 (37%), Gaps = 91/370 (24%)

Query: 36  PQGPSP-QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94
           P+ P P Q   KP G      +PQ   P     P  PPP   P  PPP+     SP SPP
Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPE----ESPTSPP 461

Query: 95  GKPQ--GPPPQGGNQPQGP-----------------PPPPGKPQGPPPQGG------NRP 129
            +     PPP+    P  P                 PPP   P  PPP+          P
Sbjct: 462 PEASRLSPPPE--ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519

Query: 130 QGPP---PPG----KPQGPPPQGDK-----SRSPRSPPGK--PQGPPPQGGNQPQGP--- 172
             PP   PP      P  PPP+          SP SPP +  P  PPP+       P   
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579

Query: 173 ---PPPPGKPQGPPPQGGK-------KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGP 222
              PPP   P  PPP+  +        P  PPP   P  PPP+   SR S  P   P  P
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA--SRLSPPPEDSPMSP 637

Query: 223 PPQGGNQPQGPPP--------PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSA 274
           PP+    P  PPP        P      PPP+    P  PPP   P  PP +    S+ +
Sbjct: 638 PPE--ESPMSPPPEVSRLSPLPVVSRLSPPPE--ESPLSPPPEESPTSPPPEA---SRLS 690

Query: 275 RSPPGKPQGPPQQEGNNPQGPPP------------PAGGNPQQPQAPPAGQ-PQGPPRPP 321
             P   P  PP ++  +P  PPP            P    P++PQ  P  + P   PRP 
Sbjct: 691 PPPEDSPTSPPPED--SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748

Query: 322 QGGRPSRPPQ 331
           +     RP +
Sbjct: 749 EPHLSPRPEE 758



 Score =  124 bits (312), Expect = 9e-29
 Identities = 106/361 (29%), Positives = 132/361 (36%), Gaps = 80/361 (22%)

Query: 35  NPQGPSPQGGNKPQGPPP-----------PPGKPQGPPPQGG-NKPQGPPPPGKPQGPPP 82
           +P  P P+    P  PPP           P   P+  PP      P  PPP   P  PP 
Sbjct: 492 SPLSPPPE--ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549

Query: 83  QGDKSRSPRSPPGK--PQGPPPQGGNQPQGP------PPPPGKPQGPPPQGGN------- 127
           +     SP SPP +  P  PPP+       P      PPP   P  PPP+          
Sbjct: 550 E----ESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605

Query: 128 RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP--------PPGKP 179
            P  PPP   P  PPP+  +   P  P   P  PPP+    P  PPP        P    
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPP--PEDSPMSPPPE--ESPMSPPPEVSRLSPLPVVSR 661

Query: 180 QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP--- 236
             PPP+  + P  PPP   P  PPP+   SR S  P   P  PPP+  + P  PPP    
Sbjct: 662 LSPPPE--ESPLSPPPEESPTSPPPEA--SRLSPPPEDSPTSPPPE--DSPASPPPEDSL 715

Query: 237 -------------PGKPQGPP----PQGGNKPQGP---PPPGKPQ-GPPAQGGSKSQSAR 275
                        P +PQ  P    P    +P+ P   P P +P   P A+    S    
Sbjct: 716 MSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE 775

Query: 276 SP-----PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
            P     P +P   PQ EG +    P     +PQ  +   +  P+ P   PQ       P
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835

Query: 331 Q 331
           Q
Sbjct: 836 Q 836



 Score =  124 bits (310), Expect = 2e-28
 Identities = 102/325 (31%), Positives = 127/325 (39%), Gaps = 50/325 (15%)

Query: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85
           EESP      P+   P    +    PPP   P  PP +    P  PPP   P  PPP+  
Sbjct: 516 EESP---LSPPEESPPSPALETPLSPPPEASPLSPPFE--ESPLSPPPEELPTSPPPEAS 570

Query: 86  KSRSPRSPPGKPQGPPPQGGNQPQGPPP------PPGK--PQGPPPQGGNRPQGPPPPGK 137
           +   P  P   P  PPP+    P  PPP      PP +  P  PPP+    P  PPP   
Sbjct: 571 RLSPP--PEESPMSPPPE--ESPMSPPPEASRLFPPFEESPLSPPPE--ESPLSPPPEAS 624

Query: 138 PQGPPPQGDKSRSPRSPPGK--PQGPPPQGGNQPQGP------PPPPGKPQGPPPQGGKK 189
              PPP+     SP SPP +  P  PPP+       P      PPP   P  PPP+  + 
Sbjct: 625 RLSPPPED----SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE--ES 678

Query: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
           P  PPP      PPP+   S +S  P   P  PPP+           P  P    PQ   
Sbjct: 679 PTSPPPEASRLSPPPED--SPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736

Query: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSP-PGKPQGPPQQEGN--NPQGPPPPAGGNPQQP 306
           + +GP    +P+ P            SP P +P   PQ E    +PQ   P     P++P
Sbjct: 737 RSEGPHLSPRPEEPHL----------SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786

Query: 307 QAPPAGQPQGPPRPPQGGRPSRPPQ 331
              P  Q +GP   PQ       PQ
Sbjct: 787 HLSP--QAEGPHLSPQPEELHLSPQ 809



 Score =  119 bits (299), Expect = 3e-27
 Identities = 102/346 (29%), Positives = 129/346 (37%), Gaps = 63/346 (18%)

Query: 25  QEESPSLIAGNPQGPSPQGGNKPQGPP--------PPPGKPQGPPPQGGN-------KPQ 69
           +E  PS     P  P P+    P  PP        PP   P  PPP+           P 
Sbjct: 524 EESPPSPALETPLSPPPEAS--PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM 581

Query: 70  GPPPPGKPQGPPPQGDK-----SRSPRSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPP 122
            PPP   P  PPP+  +       SP SPP +  P  PPP+        PPP   P  PP
Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS---PPPEDSPMSPP 638

Query: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182
           P+    P  PPP      P P   +   P  P   P  PPP+    P  PPP   +   P
Sbjct: 639 PE--ESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPE--ESPTSPPPEASR-LSP 691

Query: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRS---SQSP----PGKPQ----------GPPPQ 225
           PP+    P  PPP   P  PPP+ D   S    +SP    P +PQ           P P+
Sbjct: 692 PPEDS--PTSPPPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748

Query: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP 285
             +    P  P   PQ   P    +P+ P     P+ P       S  A  P   PQ  P
Sbjct: 749 EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP-----HLSPQAEGPHLSPQ--P 801

Query: 286 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
           ++   +PQ   P     P++P   P  QP+     PQ   P   P+
Sbjct: 802 EELHLSPQTEEPHLSPVPEEPCLSP--QPEESHLSPQSEEPCLSPR 845



 Score =  106 bits (265), Expect = 3e-23
 Identities = 96/337 (28%), Positives = 118/337 (35%), Gaps = 82/337 (24%)

Query: 61  PPQGGNKPQGPPPP--GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP 118
           PP+ G+ P   P       QG P  G  +      PG     P Q   +P G      +P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG-----PLQCEAKPLGKAGVQLEP 428

Query: 119 QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--GPPPQGGNQPQGP---- 172
           Q   P     P  PPP   P  PPP+     SP SPP +     PPP+    P  P    
Sbjct: 429 QLEAPLNEEMPLLPPPEESPLSPPPE----ESPTSPPPEASRLSPPPE--ELPASPLPEA 482

Query: 173 -------------PPPPGKPQGPPPQGG------KKPQGPP---PPG----KPQGPPPQG 206
                        PPP   P  PPP+        + P  PP   PP      P  PPP+ 
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA 542

Query: 207 -------DKSRSSQSPPGKPQGPPPQGGNQPQGP------PPPPGKPQGPPPQGG----- 248
                  ++S  S  P   P  PPP+       P      PPP   P  PPP+       
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602

Query: 249 --NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306
               P  PPP   P  PP +    S+ +  P   P  PP +E  +P  PPP        P
Sbjct: 603 FEESPLSPPPEESPLSPPPEA---SRLSPPPEDSPMSPPPEE--SPMSPPPEVSRLSPLP 657

Query: 307 -----QAPPAGQPQGPP-------RPPQGGRPSRPPQ 331
                  PP   P  PP        PP+  R S PP+
Sbjct: 658 VVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPE 694



 Score =  100 bits (249), Expect = 2e-21
 Identities = 105/413 (25%), Positives = 132/413 (31%), Gaps = 121/413 (29%)

Query: 36  PQGPSPQGGNKPQGP------PPPPGKPQGPPPQGGN-------KPQGPPPPGKPQGPPP 82
           P  P P+       P      PPP   P  PPP+           P  PPP   P  PPP
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621

Query: 83  QGDK-----SRSPRSPPGK--PQGPPPQGGNQPQGP---------------PPPPGKPQG 120
           +  +       SP SPP +  P  PPP+       P               PPP   P  
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681

Query: 121 PPPQGG-------NRPQGPPPPGKPQGPPPQGDKSRSP--RSP----PGKPQ-------- 159
           PPP+         + P  PPP   P  PPP+      P   SP    P +PQ        
Sbjct: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP 741

Query: 160 --GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP--PPQGDKSRSSQSP 215
              P P+  +    P  P   PQ   P    +P+ P     P+ P   PQ +    S  P
Sbjct: 742 HLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP 801

Query: 216 PG---KPQGPPPQGGNQPQGP-----------------------------------PPPP 237
                 PQ   P     P+ P                                   PP  
Sbjct: 802 EELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS 861

Query: 238 GKPQGPPPQGGNKPQGP-----PPPGKPQGPPAQGGSKSQSARSPPGKPQ---------- 282
            +P+ PP + G  P        PPPG+P   P  G    + A S PG+P           
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG----EPALSEPGEPPLSPLPEELPL 917

Query: 283 GPPQQEGNNPQGPPPPAGGNPQQP----QAPPAGQPQGPPRPPQGGRPSRPPQ 331
            P  +   +PQ  PP     P  P     APPA  P G    P G +    P+
Sbjct: 918 SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE 970



 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 92/304 (30%), Positives = 111/304 (36%), Gaps = 56/304 (18%)

Query: 33   AGNPQGPSPQGGNKPQGPPP-------PPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQG 84
            A   +  SP  G +PQ PPP       PP  P    P     P   PP   +PQ PPP+ 
Sbjct: 2335 ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES 2394

Query: 85   DKSRSPRSPPGK-----PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ 139
              +  PRS P       P  P  Q  +Q    P P       P     R Q P P  +  
Sbjct: 2395 CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR-- 2452

Query: 140  GPPPQGDKSRSPRSPPGKPQGPPP----------------QGGNQPQGPPPPPGK----- 178
              PP   +SR P +P  KP  P P                 GG     P  P G+     
Sbjct: 2453 --PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510

Query: 179  PQGPPPQGGKKP-----QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233
            P G PP   + P      G P P +   P   G+   S + P  +P  PPP G N   GP
Sbjct: 2511 PSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP--SLKPPVPQPGLPPPHGINSHFGP 2568

Query: 234  PPPPGKPQGP--PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG---PPQQE 288
             P  GKPQ        GN      P G P GP    GS  +S    P +P     PP  +
Sbjct: 2569 GPTLGKPQSTNYTVATGNF----HPSGSPLGP--SSGSTGESYGLSPLRPPSVLPPPAPD 2622

Query: 289  GNNP 292
            G+ P
Sbjct: 2623 GSLP 2626



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 91/354 (25%), Positives = 124/354 (35%), Gaps = 72/354 (20%)

Query: 35   NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-----------------PGKP 77
            +P  P P+        PPP   P  PPP+  + P  PPP                 P +P
Sbjct: 678  SPTSPPPEASRLS---PPPEDSPTSPPPE--DSPASPPPEDSLMSLPLEESPLLPLPEEP 732

Query: 78   Q------GP-----PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP------------PPP 114
            Q      GP     P +   S  P  P   PQ   P    QP+ P            P  
Sbjct: 733  QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792

Query: 115  PGKPQGPPPQG------GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
             G    P P+          P   P P +P   P   +   SP+S        P +    
Sbjct: 793  EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852

Query: 169  PQGPPPPPG-KPQGPPPQGGKKPQGP-----PPPGKPQGPPPQGDKSRS-------SQSP 215
            P+   PP   +P+ PP + G+ P        PPPG+P   P  G+ + S       S  P
Sbjct: 853  PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP 912

Query: 216  PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSA 274
               P  P  +    PQ  PP P  P   P      P    P G+ + P  A+G S  +S 
Sbjct: 913  EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESP 972

Query: 275  RSPP---GKPQGPPQQEGNNPQGPPP----PAGGNPQQPQAPPAGQPQGPPRPP 321
             + P        PP+    +P+  PP    P+ G+P  P +P   +P  P   P
Sbjct: 973  LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSP 1026



 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 97/361 (26%), Positives = 118/361 (32%), Gaps = 71/361 (19%)

Query: 36   PQGPSPQGG--NKPQGPPPPPGKPQGP-----PPQGGNKPQ-GPPPPGKPQGPPP----- 82
            P+ P   GG  ++P   PPP G+ +          G + P  GPP  G    P       
Sbjct: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317

Query: 83   -----QGDKSRSPRSPPGKPQGPPPQG-GNQPQGPPP-------PPGKPQGPPPQGGNRP 129
                   D  ++P +P      P   G G +PQ PPP       PP  P    P     P
Sbjct: 2318 GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDP 2377

Query: 130  QGPPP-PGKPQGPPPQGDKSRSPRSPPGKP-----QGPPPQGGNQPQGPPPPPGKPQGPP 183
               PP   +PQ PPP+   +  PRS P  P       P  Q  +Q    P P       P
Sbjct: 2378 YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437

Query: 184  PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ-------------GGNQP 230
                 + Q P P  +P   P   D       PP +PQ P                GG   
Sbjct: 2438 SPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGSLAHTSLGAGGFPA 2496

Query: 231  QGPPPPPGK-----PQGPPPQGGNKPQ-----GPPPPGKPQGPPAQGGSKSQSARSPPGK 280
              P  P G+     P G PP     P      G P P +   P A G    + +  PP  
Sbjct: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVG----EPSLKPPVP 2552

Query: 281  PQGPPQQEGNNPQGPPPPAGGNPQ-----------QPQAPPAGQPQGPPRPPQGGRPSRP 329
              G P   G N    P P  G PQ            P   P G   G      G  P RP
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612

Query: 330  P 330
            P
Sbjct: 2613 P 2613



 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 105/395 (26%), Positives = 132/395 (33%), Gaps = 109/395 (27%)

Query: 35   NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-------------------PPG 75
            +P G +P    +P+ P  PP  P  P P G   P  PP                   PPG
Sbjct: 2175 DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA--PAQPPMLGASSRPGAGQPGEFHTTPPG 2232

Query: 76   KPQGPPPQGDKSRSPRSPP----GKPQGPPPQGG--NQPQGPPPPPGKPQ---------- 119
             P+  P   D    PR P       P+ P   GG  ++P   PPP G+ +          
Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292

Query: 120  -------GPP-------PQGGN------------------------RPQGPPPPGKPQGP 141
                   GPP       P  G                          PQ P    +PQ P
Sbjct: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP 2352

Query: 142  PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201
            PP   ++ +P SPP  P    P     P   PP   +PQ PPP+        PP   P  
Sbjct: 2353 PPA--QALAP-SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE---SCCALPPRSLPSD 2406

Query: 202  PPPQGDKSRSSQSPPGKPQGPPPQGGN---------QPQGPPP---PPGKPQGPPPQGG- 248
            P  +   S  SQS    P  P P             + Q P P   PP +PQ   P    
Sbjct: 2407 PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466

Query: 249  NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP-QQEGNNPQGPPP-----PAGG- 301
            +KP  P PP       +   +   +   P   P GP  +     P G PP     P  G 
Sbjct: 2467 HKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGA 2526

Query: 302  -----NPQQPQAPPA-GQPQGPPRPPQGGRPSRPP 330
                 +P +   P A G+P   P  PQ G P  PP
Sbjct: 2527 FVGTPSPMRFTFPQAVGEPSLKPPVPQPGLP--PP 2559



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 91/321 (28%), Positives = 108/321 (33%), Gaps = 49/321 (15%)

Query: 36   PQGPSPQGGNKPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            PQ P+      P G  P     P  P  PP      P  P P G P  PP  G  SR   
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTY----PPYPSPTGAPAQPPMLGASSRPGA 2220

Query: 92   SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP----------PPQGGNRPQGP---PPPGKP 138
              PG+    PP         P P  KP+ P          P  GG +   P   PPP   
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280

Query: 139  QGPPPQGDKSRSPRSPPGKPQGPP-------PQGGNQPQG---PPPPPGKPQGPPPQGGK 188
                 +  K     S P    GPP       P  G    G     P   K    P     
Sbjct: 2281 SRKALEVKKEELGASSPS--YGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338

Query: 189  KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
            +PQ P    +PQ PPP       + SPP  P    P     P   PP   +PQ PPP+  
Sbjct: 2339 EPQSPGLGLRPQEPPP---AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE-- 2393

Query: 249  NKPQGPPPPGKPQGPPAQ--GGSKSQSARSPPGKPQGPPQQEGNNPQ------GPPPPAG 300
                  PP   P  P ++     +SQS+   P  P+ P   E   P         P P  
Sbjct: 2394 -SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR-PLSAEAFCPSPVTPRFQSPDPYS 2451

Query: 301  GNPQQPQA-PPAGQPQGPPRP 320
              P +PQ+  P      PPRP
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRP 2472



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 88/311 (28%), Positives = 101/311 (32%), Gaps = 74/311 (23%)

Query: 84   GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---GPP--PQGGNRPQG---PPPP 135
            GD +R    P    + PP  G     G PPP   P    G P  P G +        PP 
Sbjct: 2091 GDIARKTDRPALHLRIPPQPGA---LGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPA 2147

Query: 136  GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGKKPQGP 193
            G   GP   G+     + PP  P   P Q   G  P   P  P  P  PP      P  P
Sbjct: 2148 GSVPGPDSPGELFL--KLPPQVPAQVPSQDPFGLAP-AYPLEPRFPTAPPTY----PPYP 2200

Query: 194  PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---------- 243
             P G P  PP  G  SR     PG+    PP         P P  KP+ P          
Sbjct: 2201 SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPES 2260

Query: 244  PPQGGNKPQ----GPPPPGKPQ-----------------GPPAQGGSKSQSA-------- 274
            P  GG K       PPP G+ +                 GPP  G   S S+        
Sbjct: 2261 PGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320

Query: 275  -RSP--------PGKPQGPPQQE--GNNPQGPPPPAGGNPQQPQAP----PAGQPQGPPR 319
             ++P        P   Q  PQ    G  PQ PPP     P  P  P    P        +
Sbjct: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380

Query: 320  PPQGGRPSRPP 330
            PP   RP  PP
Sbjct: 2381 PPLTPRPQPPP 2391



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 79/284 (27%), Positives = 97/284 (34%), Gaps = 47/284 (16%)

Query: 36   PQGPSPQG--GNKPQGPPPPPGKPQGPPPQGGNKPQGP------------PPPGKP--QG 79
            PQ P P+      P+  P  P       PQ  +  Q P            P P  P  Q 
Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446

Query: 80   P-----PPQGDKSRSPRSPPGKPQGPPP-----QGGNQPQGPPPPPGKPQGPPPQGGNRP 129
            P     PP   +SR P +P  KP  P P     + G+         G P   P      P
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPA----GP 2502

Query: 130  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGPPPQG 186
             G      P G PP   +S    +  G P       PQ   +P   PP P +P  PPP G
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP-QPGLPPPHG 2561

Query: 187  GKKPQGPPPP-GKPQGPPPQGDKSRSSQSPPGKPQGPPPQG-----GNQPQGPPP--PPG 238
                 GP P  GKPQ        +  +  P G P GP         G  P  PP   PP 
Sbjct: 2562 INSHFGPGPTLGKPQS--TNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPP 2619

Query: 239  KPQGPPP---QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279
             P G  P    G ++  G   P + +  P  G   S +    PG
Sbjct: 2620 APDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG 2663



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 83/293 (28%), Positives = 104/293 (35%), Gaps = 61/293 (20%)

Query: 35   NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP--PPPGKPQGPPPQGDKSRS-PR 91
            +P+   P    +P+ PP  PG  Q P P+     + P  PPPG+P   P  G+ + S P 
Sbjct: 852  SPELEKPPLSPRPEKPPEEPG--QCPAPE-----ELPLFPPPGEPSLSPLLGEPALSEPG 904

Query: 92   SPP------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP-PPQ 144
             PP        P  P  +    PQ  PP P  P   P      P    P G+ + P   +
Sbjct: 905  EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAK 964

Query: 145  GDKS-RSPRSPP--GKPQGPPPQGGNQPQGP------PPPPGKPQGP---------PPQG 186
            GD    SP + P    P  PPP+       P      PP PG P GP         PPQ 
Sbjct: 965  GDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQC 1024

Query: 187  GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246
                Q       PQ  PP      S  SPP  P   P         P  P GK  G   +
Sbjct: 1025 SPLLQHSL---VPQNSPP------SQCSPPALPLSVP--------SPLSPIGKVVGVSDE 1067

Query: 247  GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 299
                        +P+ P  +      SA SP   P G    + + P   P PA
Sbjct: 1068 AELHEMETEKVSEPECPALE-----PSATSPLPSPMG----DLSCPAPSPAPA 1111



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 84/291 (28%), Positives = 95/291 (32%), Gaps = 37/291 (12%)

Query: 43   GGNKPQGPPPPPGK-----PQGPPPQGGNKPQ-----GPPPPGKPQGPPPQGDKSRSPRS 92
            GG     P  P G+     P G PP     P      G P P +   P   G+ S  P  
Sbjct: 2492 GGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV 2551

Query: 93   PPGKPQGPPPQGGNQPQGPPPPPGKPQG---PPPQGGNRPQGPP-PPGKPQGPPPQGDKS 148
            P  +P  PPP G N   GP P  GKPQ        G   P G P  P         G   
Sbjct: 2552 P--QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP 2609

Query: 149  RSPRS--PPGKPQGPPP---QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
              P S  PP  P G  P    G +Q  G   P  K + P    G        PG  Q P 
Sbjct: 2610 LRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG-TQDPG 2668

Query: 204  PQG------DKSRSSQSPPGKPQGPPPQGG--NQPQGPPPPPGKPQGPPPQGGNKPQGP- 254
              G      +K R  Q           Q     Q +          GPP   G +P  P 
Sbjct: 2669 MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728

Query: 255  -PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG-----PPPPA 299
                 + Q P A    KS     PP K  GP    G+ P       PPPPA
Sbjct: 2729 FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPA 2779



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 111/437 (25%), Positives = 125/437 (28%), Gaps = 148/437 (33%)

Query: 29   PSLIAGNPQG--PSPQGGNKPQGPPPPPGKPQ--------------GPP--PQGGN---- 66
            PSL    PQ   P P G N   GP P  GKPQ              G P  P  G+    
Sbjct: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGES 2604

Query: 67   ---KPQGPP---PPGKPQGPPP---QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 117
                P  PP   PP  P G  P    G   RS  + P + +  P  G          PG 
Sbjct: 2605 YGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGT 2664

Query: 118  PQ------------------------------------------------GPPPQGGNRP 129
                                                              GPP   G  P
Sbjct: 2665 QDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEP 2724

Query: 130  QGPPPPGKPQGPPPQG---DKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGP 182
              P      +G  P     DKS     PP K  GP    G+ P       PPPP  P   
Sbjct: 2725 SSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSM 2784

Query: 183  PPQ-----GGKKP--QGPPPPGKPQGPPPQGDKSRSSQSPPGK----------PQGPPPQ 225
                    GG +   Q  P PG       Q    +  Q+              P  P P+
Sbjct: 2785 DVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPE 2844

Query: 226  GGNQPQGPP--------PPPGKPQGPPP------------QGGNKPQGPPPPGKPQGPP- 264
             G Q  G P        P PG+P   P             Q G  P G P PG  QGPP 
Sbjct: 2845 LGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPG--QGPPQ 2902

Query: 265  --------------AQGGSKSQSARS-PPGKPQGPPQQEGNNPQGPPPPAGGNPQQP--- 306
                          A  G +  +    PP KP  PP  E NN   P P   G P  P   
Sbjct: 2903 RPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKG-PTLPTGL 2961

Query: 307  ---QAPPAGQPQGPPRP 320
                 PP+    G P P
Sbjct: 2962 ELVNRPPSSTELGRPNP 2978



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 37/94 (39%), Positives = 43/94 (45%), Gaps = 13/94 (13%)

Query: 54   PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP--PQGGNQPQGP 111
            PG   GP  + G    GP P G P+ P P G  S  P   P  P  PP  PQ   +P   
Sbjct: 4267 PGPQTGPLQELG---AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL 4323

Query: 112  PPP----PGKPQGPPPQGGN-RPQGP---PPPGK 137
            P P    P + Q PP   G  +PQGP   PPPG+
Sbjct: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 103/403 (25%), Positives = 126/403 (31%), Gaps = 104/403 (25%)

Query: 6    LSVALLALSSAQN-LNEDVSQE--ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPP 62
            L   LL     QN ++  VS E  E PS   G P       G  P+     PG+ +  P 
Sbjct: 4015 LGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI----GTTPESMATEPGEVK--PS 4068

Query: 63   QGGN------KPQGPPPPGKPQGPPPQ-------------------------GDKSRSPR 91
              G+      +PQ  P P   Q  PP                             S    
Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128

Query: 92   SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP----PPQGGNRPQGPPPPG----KPQGPPP 143
            S P     P    G+QP         PQ P    P Q    PQ PP PG      QG P 
Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ-PPKPGPVLQSGQGLPG 4187

Query: 144  --------------QGDKSRSPRSPPGKPQGPPP-----------QGGNQPQGPPPPPGK 178
                          QG  +++P+     PQ               Q     Q PP     
Sbjct: 4188 VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG 4247

Query: 179  PQGPPPQG--GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
             Q  P QG  G +PQ    PG   GP  +               GP PQG   P+ P PP
Sbjct: 4248 TQTSPLQGLLGCQPQLGGFPGPQTGPLQE------------LGAGPRPQG--PPRLPAPP 4293

Query: 237  PGKPQGP---PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
                 GP   P      P  P  P +P   P+        A+ PP  P  P       PQ
Sbjct: 4294 GALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP------KPQ 4347

Query: 294  GP---PPPAGGNPQQPQAPPA--GQPQGPPRPPQGGRPSRPPQ 331
            GP   PPP   +P   Q       +  GP  PP     ++ P+
Sbjct: 4348 GPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 7/77 (9%)

Query: 255  PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 314
            PPP +P  PP      S  A SP   P  P  +    P   PP     P    +P + +P
Sbjct: 4909 PPPEEPSPPP------SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA-SSPESARP 4961

Query: 315  QGPPRPPQGGRPSRPPQ 331
            +   RPP+ G  SRPP+
Sbjct: 4962 KPRARPPEEGEDSRPPR 4978



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 64/253 (25%), Positives = 82/253 (32%), Gaps = 40/253 (15%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ-----GGNKP--QGPPPPGKPQGPP 81
            PS ++G   GP     +     PPPP  P           GG++   Q  P PG      
Sbjct: 2753 PSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQ 2812

Query: 82   PQGDKSRSPRSPPGK----------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
             Q    +  ++              P  P P+ G Q  G P      + P P       G
Sbjct: 2813 QQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGP-------G 2865

Query: 132  PPPPGKPQGPPP------QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185
             P PG P GP           K   P   P   QGPP +    P    P    P+G    
Sbjct: 2866 EPVPG-PAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEG---L 2921

Query: 186  GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP---GKPQG 242
             G    G PP  KP  PP    +  +S  P    +GP    G +    PP     G+P  
Sbjct: 2922 RGLAVSGLPPQ-KPSAPP--APELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978

Query: 243  PPPQGGNKPQGPP 255
               + G  P   P
Sbjct: 2979 LALEAGKLPCEDP 2991



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 61/240 (25%), Positives = 79/240 (32%), Gaps = 35/240 (14%)

Query: 24   SQEESP--SLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
            S  ESP  + I   P  P P+       P PP   P  P       P GP  P   +  P
Sbjct: 967  SDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSP-----GSPVGPASPILMEPLP 1021

Query: 82   PQG----DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG---------NR 128
            PQ       S  P++ P     PP    + P  P  P GK  G   +           + 
Sbjct: 1022 PQCSPLLQHSLVPQNSPPSQCSPPALPLSVP-SPLSPIGKVVGVSDEAELHEMETEKVSE 1080

Query: 129  PQGP--PPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPPPPPGKP 179
            P+ P   P      P P GD S    SP        G  +   P  G    G  P PG+ 
Sbjct: 1081 PECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQ- 1139

Query: 180  QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP--PPPP 237
               P     + +G P    P+   P        +      QG P +   +P+ P  P PP
Sbjct: 1140 --TPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPP 1197



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 17/85 (20%)

Query: 68   PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127
            P+ P PP  P  P        SP SPP +P    P    +P   PP P     P P   +
Sbjct: 4911 PEEPSPPPSPLAP--------SPASPPTEPLVELP---TEPLAEPPVP----SPLPLASS 4955

Query: 128  RPQGPPPPGKPQGPPPQGDKSRSPR 152
                 P P     PP +G+ SR PR
Sbjct: 4956 PESARPKP--RARPPEEGEDSRPPR 4978



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 71/242 (29%), Positives = 84/242 (34%), Gaps = 47/242 (19%)

Query: 87   SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNR--PQGPPPPGKPQGPP 142
            S+SPR     P    P  G QP         PQGPP    GG R  P G   PG+P GP 
Sbjct: 3622 SQSPRLLTKLPGQLLPGHGLQP---------PQGPPGGQAGGLRLTPGGMALPGQPGGPF 3672

Query: 143  PQGDKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
                 ++  +       G    P GG  P        +  GP  +  ++ Q      + Q
Sbjct: 3673 LNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLAL---RSLGPDSRLLQERQLQLQQQRMQ 3729

Query: 201  GPPPQGDKSRSSQSPPGKPQ---GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
                   K +  Q    + Q   G       Q QGP     +  GP      KPQG  PP
Sbjct: 3730 ----LAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGP------KPQGLMPP 3779

Query: 258  GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 317
               QG   Q  S        P  PQGP        QG   PA     Q Q P A  PQGP
Sbjct: 3780 SSHQGLLVQQLS--------PQPPQGP--------QGMLGPAQVAVLQQQHPGALGPQGP 3823

Query: 318  PR 319
             R
Sbjct: 3824 HR 3825



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 40/155 (25%), Positives = 52/155 (33%), Gaps = 35/155 (22%)

Query: 49   GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP----------PPQGDKSRSPRSPPGKPQ 98
            G  P  G+ +GP    G K +G        GP          P    KS+       K +
Sbjct: 4827 GTEPKKGEAEGP----GGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQE 4882

Query: 99   GPPPQGGNQP------------QGPPPPPGKPQGPPPQGGNRPQGPPP------PGKPQG 140
             P P+   Q             Q   PPP +P  PP      P  PP       P +P  
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942

Query: 141  PPPQGDK---SRSPRSPPGKPQGPPPQGGNQPQGP 172
             PP       + SP S   KP+  PP+ G   + P
Sbjct: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 13/79 (16%)

Query: 129  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGG 187
            P+ P PP  P  P        SP SPP +P    P    +P   PP P   P    P+  
Sbjct: 4911 PEEPSPPPSPLAP--------SPASPPTEPLVELP---TEPLAEPPVPSPLPLASSPESA 4959

Query: 188  K-KPQGPPPPGKPQGPPPQ 205
            + KP+  PP       PP+
Sbjct: 4960 RPKPRARPPEEGEDSRPPR 4978



 Score = 35.4 bits (80), Expect = 0.071
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 9/69 (13%)

Query: 174  PPPGKPQGPPPQGGKKPQGPPP------PGKPQGPPPQGDKSRSSQSPPG---KPQGPPP 224
            PPP +P  PP      P  PP       P +P   PP       + SP     KP+  PP
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968

Query: 225  QGGNQPQGP 233
            + G   + P
Sbjct: 4969 EEGEDSRPP 4977



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 19/67 (28%), Positives = 25/67 (37%), Gaps = 2/67 (2%)

Query: 190  PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG--KPQGPPPQG 247
            P+ P PP  P  P P    +      P +P   PP     P    P     KP+  PP+ 
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970

Query: 248  GNKPQGP 254
            G   + P
Sbjct: 4971 GEDSRPP 4977



 Score = 32.3 bits (72), Expect = 0.60
 Identities = 31/81 (38%), Positives = 33/81 (40%), Gaps = 13/81 (16%)

Query: 168  QPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQG--PPPQ 225
            Q QGP     +  GP      KPQG  PP   QG   Q    + S  PP  PQG   P Q
Sbjct: 3757 QQQGPGVQTNQALGP------KPQGLMPPSSHQGLLVQ----QLSPQPPQGPQGMLGPAQ 3806

Query: 226  GGNQPQGPPPPPGKPQGPPPQ 246
                 Q  P   G PQGP  Q
Sbjct: 3807 VAVLQQQHPGALG-PQGPHRQ 3826



 Score = 32.0 bits (71), Expect = 0.78
 Identities = 37/111 (33%), Positives = 43/111 (38%), Gaps = 17/111 (15%)

Query: 16   AQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 75
            AQ L +   Q++    + G       Q     QGP     +  GP      KPQG  PP 
Sbjct: 3731 AQKLQQQQQQQQQQQHLLGQVAIQQQQ----QQGPGVQTNQALGP------KPQGLMPPS 3780

Query: 76   KPQGPPPQGDKSRSPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQ 124
              QG   Q     SP+ P G PQG   P Q     Q  P   G PQGP  Q
Sbjct: 3781 SHQGLLVQ---QLSPQPPQG-PQGMLGPAQVAVLQQQHPGALG-PQGPHRQ 3826



 Score = 32.0 bits (71), Expect = 0.78
 Identities = 22/77 (28%), Positives = 28/77 (36%), Gaps = 8/77 (10%)

Query: 207  DKSRSSQSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPG--- 258
            D  + S  PP +P  PP      P  PP       P +P   PP     P    P     
Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARP 4961

Query: 259  KPQGPPAQGGSKSQSAR 275
            KP+  P + G  S+  R
Sbjct: 4962 KPRARPPEEGEDSRPPR 4978



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 31/81 (38%), Positives = 34/81 (41%), Gaps = 13/81 (16%)

Query: 107  QPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG--PPPQ 164
            Q QGP     +  GP      +PQG  PP   QG   Q     SP+ P G PQG   P Q
Sbjct: 3757 QQQGPGVQTNQALGP------KPQGLMPPSSHQGLLVQ---QLSPQPPQG-PQGMLGPAQ 3806

Query: 165  GGNQPQGPPPPPGKPQGPPPQ 185
                 Q  P   G PQGP  Q
Sbjct: 3807 VAVLQQQHPGALG-PQGPHRQ 3826



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 50/205 (24%), Positives = 59/205 (28%), Gaps = 41/205 (20%)

Query: 116  GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
            G P+     G  R + P       GP    ++SR      GK   P P+ G     P   
Sbjct: 1802 GTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLE---GKADTPGPEDGGVKASP--- 1855

Query: 176  PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ-------GGN 228
                          P  P  PG P       D  R S     K +    Q       G  
Sbjct: 1856 -------------VPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSE 1902

Query: 229  QPQ----GPPPPPGKP---QGPPPQG----GNKPQGPPP---PGKPQGPPAQGGSKSQSA 274
            + Q    G P   G     Q P  QG    GN P   P    PG  Q P      +    
Sbjct: 1903 REQHLGCGTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFF 1962

Query: 275  RSPPGKPQGP-PQQEGNNPQGPPPP 298
               PG+P  P     G  P  P  P
Sbjct: 1963 SPEPGEPDSPWTGSGGTTPSTPTTP 1987


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  141 bits (355), Expect = 9e-34
 Identities = 119/356 (33%), Positives = 143/356 (40%), Gaps = 69/356 (19%)

Query: 36   PQGPS----PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKS-RS 89
            PQG +    P G     GPP PPG+   P   G    +G P PPG P    P G +    
Sbjct: 843  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902

Query: 90   PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQGDK- 147
             R  PG   GP  +G   P GPP P G P      G   P GPP    PQGPP   G+K 
Sbjct: 903  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 962

Query: 148  ---SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-----PQGPPPQGGKK-------PQG 192
                + P  P G+     P G   P GPP   G+       G P Q G K       P G
Sbjct: 963  VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1022

Query: 193  PPPPGKPQGPP-------------PQG-------DKSRSSQSPPGK--PQGPPPQGGNQ- 229
            PP P  P G P             PQG       + +R    PPG    QG P   G + 
Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1082

Query: 230  ------PQGPPPPPGKPQGPP-PQGGNKPQGPP-------PPGKPQGPPAQGGSKSQSAR 275
                  P GPP PPG P+GP  P G + PQGPP       PPG+ +G P + GS      
Sbjct: 1083 ETGDVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGE-KGEPGESGSPGIQGE 1140

Query: 276  SPPGKPQGPPQQEGNN-------PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 324
                 P+G   ++G +       P GP  P G +  +    P G P  P  P +GG
Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1196



 Score =  140 bits (353), Expect = 2e-33
 Identities = 118/355 (33%), Positives = 133/355 (37%), Gaps = 52/355 (14%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQG 84
            +  P    G        GG+ P GPP   G P    P G   P+GPP PPGK   P   G
Sbjct: 762  QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 821

Query: 85   DKSR-------SPRSPPG--KPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
             +          P  PPG   PQG      P G     GPP PPG+   P   G    +G
Sbjct: 822  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 881

Query: 132  PP-PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
             P PPG P    P G +     R  PG   GP  +G   P GPP P G P      G   
Sbjct: 882  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 190  PQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQG----PPPQGGNQPQGPPPPPGK----- 239
            P GPP    PQGPP   G+K    +  P  P G      P G   P GPP   G+     
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1001

Query: 240  PQGPPPQGGNK-------PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG--- 289
              G P Q G K       P GPP P  P G P   G+  +     P    G    EG   
Sbjct: 1002 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1061

Query: 290  -NNPQGP------PPPAGG-------NPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
             N P GP      P P+G         P  P  PP   P+GP  P     P  PP
Sbjct: 1062 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG--PRGPAGPNGADGPQGPP 1114



 Score =  140 bits (352), Expect = 2e-33
 Identities = 121/358 (33%), Positives = 147/358 (41%), Gaps = 72/358 (20%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKS--- 87
            + G   GP  +G   P GPP P G P      G   P GPP    PQGPP   G+K    
Sbjct: 906  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 965

Query: 88   -RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGGNR-------PQGPPP 134
             + P  P G+     P G   P GPP   G+       G P Q G +       P GPP 
Sbjct: 966  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025

Query: 135  PGKPQGPP-------------PQG-------DKSRSPRSPPGKP--QGPPPQGGNQ---- 168
            P  P G P             PQG       + +R    PPG    QG P   G +    
Sbjct: 1026 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085

Query: 169  ---PQGPPPPPGKPQGPP-PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP--PGKPQGP 222
               P GPP PPG P+GP  P G   PQGPP      GPP +  +   S SP   G+P   
Sbjct: 1086 DVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1144

Query: 223  PPQGGNQPQGPPPPPGKPQGPP----PQGGNKPQGPPP----PGKPQGPPAQGGSKSQSA 274
             P+G    +G    PG+P GPP    P G + P+G P     PG P GPP +GG + Q  
Sbjct: 1145 GPRGERGEKGESGQPGEP-GPPGPKGPTGDDGPKGNPGPVGFPGDP-GPPGEGGPRGQDG 1202

Query: 275  ----RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
                R   G+P  P         GPP P G      +  PAG P    R  QGG+ ++
Sbjct: 1203 AKGDRGEDGEPGQPGSPGPTGENGPPGPLG------KRGPAGSPGSEGR--QGGKGAK 1252



 Score =  133 bits (334), Expect = 3e-31
 Identities = 112/342 (32%), Positives = 125/342 (36%), Gaps = 49/342 (14%)

Query: 27   ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-------------- 72
            E P    G    P P G    +G    PG P  P  QG     G P              
Sbjct: 685  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744

Query: 73   -----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127
                 P G+     P+G   R PR   GK       GG+ P GPP   G P    P G  
Sbjct: 745  SGKSGPRGERGPTGPRG--QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 128  RPQGPP-PPGKPQGPPPQGDKS----RSPRSPPGKPQGPPPQGGNQPQGP------PPPP 176
             P+GPP PPGK   P   G +     +    PPG P    PQG     GP      P PP
Sbjct: 803  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862

Query: 177  GKP--QGPPPQGGKK--PQGPPPPGKPQGPPPQGDKS-RSSQSPPGKPQGPPPQGGNQPQ 231
            G P  QG P   GK+     P PPG P    P G +     +  PG   GP  +G   P 
Sbjct: 863  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922

Query: 232  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG-- 289
            GPP P G P      G   P GPP    PQGPP   G K       P  P G    +G  
Sbjct: 923  GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 982

Query: 290  --NNPQGPPPPAG--------GNPQQPQAPPAGQPQGPPRPP 321
                P GPP  AG        G+P Q          GPP PP
Sbjct: 983  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024



 Score =  132 bits (331), Expect = 6e-31
 Identities = 119/366 (32%), Positives = 143/366 (39%), Gaps = 85/366 (23%)

Query: 38   GPSPQGGNK----PQGPPPPPGKPQGPP-PQGGNKPQGPP-------PPGKP-------- 77
            GPS + G      P GPP PPG P+GP  P G + PQGPP       PPG+         
Sbjct: 1076 GPSGEKGETGDVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134

Query: 78   ---QGPP----PQGDKSRSPRS-PPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQG 125
               QG P    P+G++     S  PG+P GPP    P G + P+G P P G P  P P G
Sbjct: 1135 PGIQGEPGVKGPRGERGEKGESGQPGEP-GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1193

Query: 126  GNRPQGPP----------PPGKPQGPPPQGDKSR----SPRSPPGKPQGPPPQGGNQPQG 171
               P+G             PG+P  P P G+         R P G P     QGG   +G
Sbjct: 1194 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1253

Query: 172  PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP----PQGDKSRSSQSPPGKPQGPP---- 223
             P   G P    P G   P G P P   +G P     QG    + Q+ P  P GPP    
Sbjct: 1254 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313

Query: 224  ---PQGGNQPQGPPP------PPGK-----------PQGPPPQGGNK----PQGPPPPGK 259
                 G    +G P       PPG+           PQG P Q G        GP  PG 
Sbjct: 1314 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1373

Query: 260  PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 319
            P G P   G K     + PG P+G    +G  P G P P G   +  Q  P   P+   R
Sbjct: 1374 PPGLPGPAGPKGAKGATGPGGPKGEKGVQG--PPGHPGPPG---EVIQPLPIQMPKKTRR 1428

Query: 320  PPQGGR 325
               G R
Sbjct: 1429 SVDGSR 1434



 Score =  123 bits (308), Expect = 3e-28
 Identities = 103/287 (35%), Positives = 120/287 (41%), Gaps = 32/287 (11%)

Query: 60  PPPQGGNKPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
           P  +G + P+GP     P G P  P   G+K +     PG P  P  QG     G P  P
Sbjct: 676 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL--GVPGLPGYPGRQGPKGSLGFPGFP 733

Query: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
           G       +G +   GP     P GP  Q    R PR   GK       GG+ P GPP  
Sbjct: 734 GASGEKGARGLSGKSGPRGERGPTGPRGQ----RGPRGATGKSGAKGTSGGDGPHGPPGE 789

Query: 176 PGKPQGPPPQGGKKPQGPP-PPGKPQGPPPQGDKS----RSSQSPPGKPQGPPPQGGNQP 230
            G P    P G   P+GPP PPGK   P   G +     +    PPG P    PQG    
Sbjct: 790 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849

Query: 231 QGP------PPPPGKP--QGPPPQGGNKPQ--GPPPPGKP--QGPPAQGGSKSQSARSPP 278
            GP      P PPG P  QG P   G +     P PPG P   GP    G   +  R  P
Sbjct: 850 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE--RGLP 907

Query: 279 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-RP-PQG 323
           G   GP  +    P GPP PA G+P +  A  +G P GPP RP PQG
Sbjct: 908 GTAGGPGLKGNEGPSGPPGPA-GSPGERGAAGSGGPIGPPGRPGPQG 953



 Score =  120 bits (300), Expect = 2e-27
 Identities = 128/400 (32%), Positives = 155/400 (38%), Gaps = 102/400 (25%)

Query: 23   VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ----------GGNKPQG-- 70
            V+ E+      G+P     +G     GPP PPG P GP  Q          G   PQG  
Sbjct: 993  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHF 1051

Query: 71   -------------PPPPGKPQG-PPPQGDKSRS----PRSPPGKP--QGPP-PQGGNQPQ 109
                         PP P   QG P P G+K  +    P  PPG P  +GP  P G + PQ
Sbjct: 1052 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQ 1111

Query: 110  GPPP------PPGKPQGPPPQGGNRPQGPP----------------PPGKPQGPPPQG-- 145
            GPP       PPG+   P   G    QG P                 PG+P  P P+G  
Sbjct: 1112 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171

Query: 146  --DKSRSPRSPPGKP--QGPPPQGGNQPQ-------GPPPPPGKPQGPPPQGGKKPQGP- 193
              D  +    P G P   GPP +GG + Q       G    PG+P  P P G   P GP 
Sbjct: 1172 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1231

Query: 194  ---PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP-----QGPPP 245
                P G P     QG K   ++  PG    P   G   P GP  P GKP     +G P 
Sbjct: 1232 GKRGPAGSPGSEGRQGGK--GAKGDPGAIGAP---GKTGPVGPAGPAGKPGPDGLRGLPG 1286

Query: 246  QGGNKPQGPP-------PPGKPQGPPAQGGSKSQS-ARSPPGKPQ-----GPPQQEG-NN 291
              G   QG P       PPG P GPP   G +  + A+   G P      GPP ++G   
Sbjct: 1287 SVGQ--QGRPGATGQAGPPG-PVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1343

Query: 292  PQGPPPPAGGNPQQPQ--APPAGQPQGPPRPPQGGRPSRP 329
             +G P P G   Q+ +   P A  P GP  PP    P+ P
Sbjct: 1344 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1383



 Score =  114 bits (285), Expect = 1e-25
 Identities = 114/361 (31%), Positives = 137/361 (37%), Gaps = 90/361 (24%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS--P 93
           PQGP  +G   PQG P PPG+   P  QG   PQG   P   +GP  +      P S  P
Sbjct: 546 PQGP--KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP 603

Query: 94  PGKP--QGPPPQGGNQ----PQGPPPPPGKPQG--------------------------- 120
           PG P  +GPP   GNQ    PQGP   PG P+G                           
Sbjct: 604 PGHPGKEGPPGTKGNQGPSGPQGPLGYPG-PRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 662

Query: 121 -------------PPPQGGNRPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163
                        P  +G + P+GP     P G P  P   G+K +     PG P  P  
Sbjct: 663 DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL--GVPGLPGYPGR 720

Query: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQGP 222
           QG   P+G    PG P     +G +   G   P   +GP  P+G   R  +   GK    
Sbjct: 721 QG---PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ--RGPRGATGKSGAK 775

Query: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGK---PQGPPAQGGSKSQSARSPP 278
              GG+ P GPP   G P    P G   P+GPP PPGK   P  P  +G    Q    PP
Sbjct: 776 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 835

Query: 279 GKP-----------QGPPQQEGN-NPQGPPPPAG-----------GNPQQPQAPPAGQPQ 315
           G P            GP  + G+  P GPP   G           G+P  P AP    P 
Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 895

Query: 316 G 316
           G
Sbjct: 896 G 896



 Score =  112 bits (279), Expect = 6e-25
 Identities = 112/363 (30%), Positives = 135/363 (37%), Gaps = 80/363 (22%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
           + G P     +G    QG P PPG+       G   P+G P    P+G          P+
Sbjct: 477 LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-------LLGPK 529

Query: 92  SPPGKPQGPP----------PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
            PPG P GPP          P+G   PQG P PPG+   P  QG   PQG   P   +GP
Sbjct: 530 GPPGIP-GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588

Query: 142 PPQGDKSRSPRS--PPGKP--QGPPPQGGNQ-PQGPPPPPGKP-----------QGPPPQ 185
             +      P S  PPG P  +GPP   GNQ P GP  P G P           +G    
Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648

Query: 186 GGKKPQGPPP-----------------PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
            G+K +   P                 PG      P+G K R+   P G P  P   G  
Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG--PTGDPGPPGLMGEK 706

Query: 229 QPQGPPPPPGKPQGPPPQG-----------GNK-------PQGPPPPGKPQGPPAQGGSK 270
              G P  PG P    P+G           G K         GP     P GP  Q G +
Sbjct: 707 GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 766

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAG-GNPQQPQAPPAGQPQGPPRPP-QGGRPSR 328
             + +S      G     G+ P GPP   G   PQ P   P   P+GPP PP + G P  
Sbjct: 767 GATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPG--PKGPPGPPGKDGLPGH 819

Query: 329 PPQ 331
           P Q
Sbjct: 820 PGQ 822



 Score =  102 bits (255), Expect = 4e-22
 Identities = 101/349 (28%), Positives = 136/349 (38%), Gaps = 45/349 (12%)

Query: 20  NEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 79
           ++D +  E   ++  +   P  +  + P+G     G+P    P  G   +GPP P  P G
Sbjct: 265 SQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEP--GMLVEGPPGPEGPAG 322

Query: 80  --PPPQGDKSRSPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQ--GGNRPQGPPP 134
              PP    +  P   PG+ +GPP + G     G P PPG     P +   G   +GP  
Sbjct: 323 LIGPPGIQGNPGPVGDPGE-RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV 381

Query: 135 PGKP--------------QGPP-PQGDKSR-SPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178
             +               +GPP P G   R  P   PG P      G   PQGP  P G 
Sbjct: 382 AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL 441

Query: 179 PQGPPPQGGKKPQGPPPP--GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
             GPP + G++ +       G P  P  +GD  R     PG P     +G    QG P P
Sbjct: 442 T-GPPGKAGRRGRAGADGARGMPGDPGVKGD--RGFDGLPGLPGEKGHRGDTGAQGLPGP 498

Query: 237 PGK-----------PQGPPPQGGNK----PQGPPP-PGKPQGPPAQGGSKSQSARSPPGK 280
           PG+           P+G P + G +    P+GPP  PG P      G    + +  P G+
Sbjct: 499 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 558

Query: 281 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           P  P QQ     QG P P G      +  P G+P  P  P   G P  P
Sbjct: 559 PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607



 Score =  100 bits (248), Expect = 2e-21
 Identities = 94/308 (30%), Positives = 117/308 (37%), Gaps = 31/308 (10%)

Query: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
           + Q  SP L  G      PQG   PQG   PPGK       G +  +G      P  P  
Sbjct: 415 LGQPGSPGL-KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG-----MPGDPGV 468

Query: 83  QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142
           +GD+       PG P     +G    QG P PPG+       G   P+G P    P+G  
Sbjct: 469 KGDRGFD--GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-- 524

Query: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGKKPQGPPPPGKP 199
                   P+ PPG P  P  +G + PQGP     P G+P  P  QG    QG P P   
Sbjct: 525 -----LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 579

Query: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259
            GP   G+K      P GKP  P   G + P G P   G P     QG + PQGP     
Sbjct: 580 IGP--HGEKG-----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 632

Query: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEGN----NPQGPPPPAGGNPQQPQAPPAGQ-- 313
           P+G     G +            G P  +G+      +G     G   +     P G+  
Sbjct: 633 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 692

Query: 314 PQGPPRPP 321
           P G P PP
Sbjct: 693 PTGDPGPP 700



 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 105/331 (31%), Positives = 134/331 (40%), Gaps = 47/331 (14%)

Query: 29  PSLIAGNPQGPS-PQGGNKP---QGPPPPPGKP--QGPPPQGG--NKPQGPPPPGKPQGP 80
           P ++   P GP  P G   P   QG P P G P  +GPP + G       P PPG     
Sbjct: 307 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 366

Query: 81  PPQ-----GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135
           P +     GDK     +   + Q    Q     +GPP P G    P P G  +P  P   
Sbjct: 367 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG--QPGSPGLK 424

Query: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGPPPQGGKKPQGPP 194
           G+     PQG     PR P G   GPP + G + + G     G P  P  +G +   G P
Sbjct: 425 GESGDLGPQG-----PRGPQGLT-GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 478

Query: 195 P-PGKP--------QG-PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGP 243
             PG+         QG P P G+           P+G P + G +   GP  PPG P  P
Sbjct: 479 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538

Query: 244 PPQGGNKPQGPP----PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP--- 296
             +G + PQGP     P G+P GPP Q G+        P    GP  ++G  PQG P   
Sbjct: 539 GVRGMDGPQGPKGSLGPQGEP-GPPGQQGTPGTQGLPGPQGAIGPHGEKG--PQGKPGLP 595

Query: 297 --PPAGGNPQQP--QAPPAGQPQGPPRPPQG 323
             P + G P  P  + PP  +    P  PQG
Sbjct: 596 GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 43/139 (30%), Positives = 53/139 (38%), Gaps = 20/139 (14%)

Query: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
           +PQ   P   + RS Q  P +   P  Q   +PQ   P PG+ +    +       PP  
Sbjct: 235 RPQNQQPHRAQ-RSPQQQPSRLHRPQNQ---EPQSQDPTPGEEE----EILESSLLPPLE 286

Query: 258 GKPQGPPAQGGSKSQSARSPPGK-PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP-- 314
               GP    G K + A   PG   +GPP  EG      PP   GNP      P G P  
Sbjct: 287 EAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNP-----GPVGDPGE 341

Query: 315 QGPP----RPPQGGRPSRP 329
           +GPP     P   G P  P
Sbjct: 342 RGPPGRAGLPGSDGAPGPP 360



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 12/70 (17%)

Query: 36   PQGPSPQGGNK----PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            PQG   Q G        GP  P G P  P P G    +G   PG P+G        +  +
Sbjct: 1350 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG-------EKGVQ 1402

Query: 92   SPPGKPQGPP 101
             PPG P GPP
Sbjct: 1403 GPPGHP-GPP 1411



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 24/102 (23%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPP-------PQGGNKPQGPP----PPGKPQGPPP 82
            G P    P G   P G P P G P+G         P+G    QGPP    PPG+   P P
Sbjct: 1361 GIPGASGPIGPGGPPGLPGPAG-PKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419

Query: 83   QGDKSRSPRSPPG----KPQGPPPQGGNQPQGPPPPPGKPQG 120
                 ++ RS  G    +     P GG         PG P G
Sbjct: 1420 IQMPKKTRRSVDGSRLMQEDEAIPTGG--------APGSPGG 1453


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  141 bits (355), Expect = 9e-34
 Identities = 119/356 (33%), Positives = 143/356 (40%), Gaps = 69/356 (19%)

Query: 36   PQGPS----PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKS-RS 89
            PQG +    P G     GPP PPG+   P   G    +G P PPG P    P G +    
Sbjct: 822  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 881

Query: 90   PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQGDK- 147
             R  PG   GP  +G   P GPP P G P      G   P GPP    PQGPP   G+K 
Sbjct: 882  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 941

Query: 148  ---SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-----PQGPPPQGGKK-------PQG 192
                + P  P G+     P G   P GPP   G+       G P Q G K       P G
Sbjct: 942  VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1001

Query: 193  PPPPGKPQGPP-------------PQG-------DKSRSSQSPPGK--PQGPPPQGGNQ- 229
            PP P  P G P             PQG       + +R    PPG    QG P   G + 
Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1061

Query: 230  ------PQGPPPPPGKPQGPP-PQGGNKPQGPP-------PPGKPQGPPAQGGSKSQSAR 275
                  P GPP PPG P+GP  P G + PQGPP       PPG+ +G P + GS      
Sbjct: 1062 ETGDVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGE-KGEPGESGSPGIQGE 1119

Query: 276  SPPGKPQGPPQQEGNN-------PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 324
                 P+G   ++G +       P GP  P G +  +    P G P  P  P +GG
Sbjct: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1175



 Score =  140 bits (353), Expect = 2e-33
 Identities = 118/355 (33%), Positives = 133/355 (37%), Gaps = 52/355 (14%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQG 84
            +  P    G        GG+ P GPP   G P    P G   P+GPP PPGK   P   G
Sbjct: 741  QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 800

Query: 85   DKSR-------SPRSPPG--KPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
             +          P  PPG   PQG      P G     GPP PPG+   P   G    +G
Sbjct: 801  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 860

Query: 132  PP-PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
             P PPG P    P G +     R  PG   GP  +G   P GPP P G P      G   
Sbjct: 861  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920

Query: 190  PQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQG----PPPQGGNQPQGPPPPPGK----- 239
            P GPP    PQGPP   G+K    +  P  P G      P G   P GPP   G+     
Sbjct: 921  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 980

Query: 240  PQGPPPQGGNK-------PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG--- 289
              G P Q G K       P GPP P  P G P   G+  +     P    G    EG   
Sbjct: 981  EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1040

Query: 290  -NNPQGP------PPPAGG-------NPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
             N P GP      P P+G         P  P  PP   P+GP  P     P  PP
Sbjct: 1041 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG--PRGPAGPNGADGPQGPP 1093



 Score =  140 bits (352), Expect = 2e-33
 Identities = 121/358 (33%), Positives = 147/358 (41%), Gaps = 72/358 (20%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKS--- 87
            + G   GP  +G   P GPP P G P      G   P GPP    PQGPP   G+K    
Sbjct: 885  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 944

Query: 88   -RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGGNR-------PQGPPP 134
             + P  P G+     P G   P GPP   G+       G P Q G +       P GPP 
Sbjct: 945  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004

Query: 135  PGKPQGPP-------------PQG-------DKSRSPRSPPGKP--QGPPPQGGNQ---- 168
            P  P G P             PQG       + +R    PPG    QG P   G +    
Sbjct: 1005 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064

Query: 169  ---PQGPPPPPGKPQGPP-PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP--PGKPQGP 222
               P GPP PPG P+GP  P G   PQGPP      GPP +  +   S SP   G+P   
Sbjct: 1065 DVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1123

Query: 223  PPQGGNQPQGPPPPPGKPQGPP----PQGGNKPQGPPP----PGKPQGPPAQGGSKSQSA 274
             P+G    +G    PG+P GPP    P G + P+G P     PG P GPP +GG + Q  
Sbjct: 1124 GPRGERGEKGESGQPGEP-GPPGPKGPTGDDGPKGNPGPVGFPGDP-GPPGEGGPRGQDG 1181

Query: 275  ----RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
                R   G+P  P         GPP P G      +  PAG P    R  QGG+ ++
Sbjct: 1182 AKGDRGEDGEPGQPGSPGPTGENGPPGPLG------KRGPAGSPGSEGR--QGGKGAK 1231



 Score =  133 bits (334), Expect = 3e-31
 Identities = 112/342 (32%), Positives = 125/342 (36%), Gaps = 49/342 (14%)

Query: 27   ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-------------- 72
            E P    G    P P G    +G    PG P  P  QG     G P              
Sbjct: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723

Query: 73   -----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127
                 P G+     P+G   R PR   GK       GG+ P GPP   G P    P G  
Sbjct: 724  SGKSGPRGERGPTGPRG--QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 128  RPQGPP-PPGKPQGPPPQGDKS----RSPRSPPGKPQGPPPQGGNQPQGP------PPPP 176
             P+GPP PPGK   P   G +     +    PPG P    PQG     GP      P PP
Sbjct: 782  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841

Query: 177  GKP--QGPPPQGGKK--PQGPPPPGKPQGPPPQGDKS-RSSQSPPGKPQGPPPQGGNQPQ 231
            G P  QG P   GK+     P PPG P    P G +     +  PG   GP  +G   P 
Sbjct: 842  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 901

Query: 232  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG-- 289
            GPP P G P      G   P GPP    PQGPP   G K       P  P G    +G  
Sbjct: 902  GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 961

Query: 290  --NNPQGPPPPAG--------GNPQQPQAPPAGQPQGPPRPP 321
                P GPP  AG        G+P Q          GPP PP
Sbjct: 962  GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1003



 Score =  132 bits (331), Expect = 6e-31
 Identities = 119/366 (32%), Positives = 143/366 (39%), Gaps = 85/366 (23%)

Query: 38   GPSPQGGNK----PQGPPPPPGKPQGPP-PQGGNKPQGPP-------PPGKP-------- 77
            GPS + G      P GPP PPG P+GP  P G + PQGPP       PPG+         
Sbjct: 1055 GPSGEKGETGDVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1113

Query: 78   ---QGPP----PQGDKSRSPRS-PPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQG 125
               QG P    P+G++     S  PG+P GPP    P G + P+G P P G P  P P G
Sbjct: 1114 PGIQGEPGVKGPRGERGEKGESGQPGEP-GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1172

Query: 126  GNRPQGPP----------PPGKPQGPPPQGDKSR----SPRSPPGKPQGPPPQGGNQPQG 171
               P+G             PG+P  P P G+         R P G P     QGG   +G
Sbjct: 1173 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1232

Query: 172  PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP----PQGDKSRSSQSPPGKPQGPP---- 223
             P   G P    P G   P G P P   +G P     QG    + Q+ P  P GPP    
Sbjct: 1233 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292

Query: 224  ---PQGGNQPQGPPP------PPGK-----------PQGPPPQGGNK----PQGPPPPGK 259
                 G    +G P       PPG+           PQG P Q G        GP  PG 
Sbjct: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1352

Query: 260  PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 319
            P G P   G K     + PG P+G    +G  P G P P G   +  Q  P   P+   R
Sbjct: 1353 PPGLPGPAGPKGAKGATGPGGPKGEKGVQG--PPGHPGPPG---EVIQPLPIQMPKKTRR 1407

Query: 320  PPQGGR 325
               G R
Sbjct: 1408 SVDGSR 1413



 Score =  123 bits (308), Expect = 3e-28
 Identities = 103/287 (35%), Positives = 120/287 (41%), Gaps = 32/287 (11%)

Query: 60  PPPQGGNKPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
           P  +G + P+GP     P G P  P   G+K +     PG P  P  QG     G P  P
Sbjct: 655 PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL--GVPGLPGYPGRQGPKGSLGFPGFP 712

Query: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
           G       +G +   GP     P GP  Q    R PR   GK       GG+ P GPP  
Sbjct: 713 GASGEKGARGLSGKSGPRGERGPTGPRGQ----RGPRGATGKSGAKGTSGGDGPHGPPGE 768

Query: 176 PGKPQGPPPQGGKKPQGPP-PPGKPQGPPPQGDKS----RSSQSPPGKPQGPPPQGGNQP 230
            G P    P G   P+GPP PPGK   P   G +     +    PPG P    PQG    
Sbjct: 769 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 828

Query: 231 QGP------PPPPGKP--QGPPPQGGNKPQ--GPPPPGKP--QGPPAQGGSKSQSARSPP 278
            GP      P PPG P  QG P   G +     P PPG P   GP    G   +  R  P
Sbjct: 829 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE--RGLP 886

Query: 279 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-RP-PQG 323
           G   GP  +    P GPP PA G+P +  A  +G P GPP RP PQG
Sbjct: 887 GTAGGPGLKGNEGPSGPPGPA-GSPGERGAAGSGGPIGPPGRPGPQG 932



 Score =  120 bits (300), Expect = 2e-27
 Identities = 128/400 (32%), Positives = 155/400 (38%), Gaps = 102/400 (25%)

Query: 23   VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ----------GGNKPQG-- 70
            V+ E+      G+P     +G     GPP PPG P GP  Q          G   PQG  
Sbjct: 972  VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHF 1030

Query: 71   -------------PPPPGKPQG-PPPQGDKSRS----PRSPPGKP--QGPP-PQGGNQPQ 109
                         PP P   QG P P G+K  +    P  PPG P  +GP  P G + PQ
Sbjct: 1031 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQ 1090

Query: 110  GPPP------PPGKPQGPPPQGGNRPQGPP----------------PPGKPQGPPPQG-- 145
            GPP       PPG+   P   G    QG P                 PG+P  P P+G  
Sbjct: 1091 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150

Query: 146  --DKSRSPRSPPGKP--QGPPPQGGNQPQ-------GPPPPPGKPQGPPPQGGKKPQGP- 193
              D  +    P G P   GPP +GG + Q       G    PG+P  P P G   P GP 
Sbjct: 1151 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1210

Query: 194  ---PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP-----QGPPP 245
                P G P     QG K   ++  PG    P   G   P GP  P GKP     +G P 
Sbjct: 1211 GKRGPAGSPGSEGRQGGK--GAKGDPGAIGAP---GKTGPVGPAGPAGKPGPDGLRGLPG 1265

Query: 246  QGGNKPQGPP-------PPGKPQGPPAQGGSKSQS-ARSPPGKPQ-----GPPQQEG-NN 291
              G   QG P       PPG P GPP   G +  + A+   G P      GPP ++G   
Sbjct: 1266 SVGQ--QGRPGATGQAGPPG-PVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1322

Query: 292  PQGPPPPAGGNPQQPQ--APPAGQPQGPPRPPQGGRPSRP 329
             +G P P G   Q+ +   P A  P GP  PP    P+ P
Sbjct: 1323 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1362



 Score =  114 bits (285), Expect = 1e-25
 Identities = 114/361 (31%), Positives = 137/361 (37%), Gaps = 90/361 (24%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS--P 93
           PQGP  +G   PQG P PPG+   P  QG   PQG   P   +GP  +      P S  P
Sbjct: 525 PQGP--KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP 582

Query: 94  PGKP--QGPPPQGGNQ----PQGPPPPPGKPQG--------------------------- 120
           PG P  +GPP   GNQ    PQGP   PG P+G                           
Sbjct: 583 PGHPGKEGPPGTKGNQGPSGPQGPLGYPG-PRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641

Query: 121 -------------PPPQGGNRPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163
                        P  +G + P+GP     P G P  P   G+K +     PG P  P  
Sbjct: 642 DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL--GVPGLPGYPGR 699

Query: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQGP 222
           QG   P+G    PG P     +G +   G   P   +GP  P+G   R  +   GK    
Sbjct: 700 QG---PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ--RGPRGATGKSGAK 754

Query: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGK---PQGPPAQGGSKSQSARSPP 278
              GG+ P GPP   G P    P G   P+GPP PPGK   P  P  +G    Q    PP
Sbjct: 755 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 814

Query: 279 GKP-----------QGPPQQEGN-NPQGPPPPAG-----------GNPQQPQAPPAGQPQ 315
           G P            GP  + G+  P GPP   G           G+P  P AP    P 
Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 874

Query: 316 G 316
           G
Sbjct: 875 G 875



 Score =  112 bits (279), Expect = 6e-25
 Identities = 112/363 (30%), Positives = 135/363 (37%), Gaps = 80/363 (22%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
           + G P     +G    QG P PPG+       G   P+G P    P+G          P+
Sbjct: 456 LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-------LLGPK 508

Query: 92  SPPGKPQGPP----------PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
            PPG P GPP          P+G   PQG P PPG+   P  QG   PQG   P   +GP
Sbjct: 509 GPPGIP-GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567

Query: 142 PPQGDKSRSPRS--PPGKP--QGPPPQGGNQ-PQGPPPPPGKP-----------QGPPPQ 185
             +      P S  PPG P  +GPP   GNQ P GP  P G P           +G    
Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627

Query: 186 GGKKPQGPPP-----------------PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
            G+K +   P                 PG      P+G K R+   P G P  P   G  
Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG--PTGDPGPPGLMGEK 685

Query: 229 QPQGPPPPPGKPQGPPPQG-----------GNK-------PQGPPPPGKPQGPPAQGGSK 270
              G P  PG P    P+G           G K         GP     P GP  Q G +
Sbjct: 686 GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 745

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAG-GNPQQPQAPPAGQPQGPPRPP-QGGRPSR 328
             + +S      G     G+ P GPP   G   PQ P   P   P+GPP PP + G P  
Sbjct: 746 GATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPG--PKGPPGPPGKDGLPGH 798

Query: 329 PPQ 331
           P Q
Sbjct: 799 PGQ 801



 Score =  104 bits (259), Expect = 1e-22
 Identities = 103/344 (29%), Positives = 133/344 (38%), Gaps = 45/344 (13%)

Query: 25  QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPP 82
           Q++   L     Q P  Q  + P+G     G+P    P  G   +GPP P  P G   PP
Sbjct: 249 QQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEP--GMLVEGPPGPEGPAGLIGPP 306

Query: 83  QGDKSRSPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQ--GGNRPQGPPPPGKP- 138
               +  P   PG+ +GPP + G     G P PPG     P +   G   +GP    +  
Sbjct: 307 GIQGNPGPVGDPGE-RGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 365

Query: 139 -------------QGPP-PQGDKSR-SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
                        +GPP P G   R  P   PG P      G   PQGP  P G   GPP
Sbjct: 366 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT-GPP 424

Query: 184 PQGGKKPQGPPPP--GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK-- 239
            + G++ +       G P  P  +GD  R     PG P     +G    QG P PPG+  
Sbjct: 425 GKAGRRGRAGADGARGMPGDPGVKGD--RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 482

Query: 240 ---------PQGPPPQGGNK----PQGPPP-PGKPQGPPAQGGSKSQSARSPPGKPQGPP 285
                    P+G P + G +    P+GPP  PG P      G    + +  P G+P  P 
Sbjct: 483 ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542

Query: 286 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           QQ     QG P P G      +  P G+P  P  P   G P  P
Sbjct: 543 QQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586



 Score =  100 bits (248), Expect = 2e-21
 Identities = 94/308 (30%), Positives = 117/308 (37%), Gaps = 31/308 (10%)

Query: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
           + Q  SP L  G      PQG   PQG   PPGK       G +  +G      P  P  
Sbjct: 394 LGQPGSPGL-KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG-----MPGDPGV 447

Query: 83  QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142
           +GD+       PG P     +G    QG P PPG+       G   P+G P    P+G  
Sbjct: 448 KGDRGFD--GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-- 503

Query: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGKKPQGPPPPGKP 199
                   P+ PPG P  P  +G + PQGP     P G+P  P  QG    QG P P   
Sbjct: 504 -----LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 558

Query: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259
            GP   G+K      P GKP  P   G + P G P   G P     QG + PQGP     
Sbjct: 559 IGP--HGEKG-----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611

Query: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEGN----NPQGPPPPAGGNPQQPQAPPAGQ-- 313
           P+G     G +            G P  +G+      +G     G   +     P G+  
Sbjct: 612 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671

Query: 314 PQGPPRPP 321
           P G P PP
Sbjct: 672 PTGDPGPP 679



 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 105/331 (31%), Positives = 134/331 (40%), Gaps = 47/331 (14%)

Query: 29  PSLIAGNPQGPS-PQGGNKP---QGPPPPPGKP--QGPPPQGG--NKPQGPPPPGKPQGP 80
           P ++   P GP  P G   P   QG P P G P  +GPP + G       P PPG     
Sbjct: 286 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 345

Query: 81  PPQ-----GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135
           P +     GDK     +   + Q    Q     +GPP P G    P P G  +P  P   
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG--QPGSPGLK 403

Query: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGPPPQGGKKPQGPP 194
           G+     PQG     PR P G   GPP + G + + G     G P  P  +G +   G P
Sbjct: 404 GESGDLGPQG-----PRGPQGLT-GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 457

Query: 195 P-PGKP--------QG-PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGP 243
             PG+         QG P P G+           P+G P + G +   GP  PPG P  P
Sbjct: 458 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 517

Query: 244 PPQGGNKPQGPP----PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP--- 296
             +G + PQGP     P G+P GPP Q G+        P    GP  ++G  PQG P   
Sbjct: 518 GVRGMDGPQGPKGSLGPQGEP-GPPGQQGTPGTQGLPGPQGAIGPHGEKG--PQGKPGLP 574

Query: 297 --PPAGGNPQQP--QAPPAGQPQGPPRPPQG 323
             P + G P  P  + PP  +    P  PQG
Sbjct: 575 GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 16/116 (13%)

Query: 225 QGGNQPQGPPPPPGKPQGPP---PQGGNKPQGPPPPGKP-QGPPAQGGSKSQSARSPPGK 280
           +GG + +     P + Q  P   P   ++PQ   P  +   GP    G K + A   PG 
Sbjct: 229 EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGM 288

Query: 281 -PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP--QGPP----RPPQGGRPSRP 329
             +GPP  EG      PP   GNP      P G P  +GPP     P   G P  P
Sbjct: 289 LVEGPPGPEGPAGLIGPPGIQGNP-----GPVGDPGERGPPGRAGLPGSDGAPGPP 339



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 12/70 (17%)

Query: 36   PQGPSPQGGNK----PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            PQG   Q G        GP  P G P  P P G    +G   PG P+G        +  +
Sbjct: 1329 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG-------EKGVQ 1381

Query: 92   SPPGKPQGPP 101
             PPG P GPP
Sbjct: 1382 GPPGHP-GPP 1390



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 24/102 (23%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPP-------PQGGNKPQGPP----PPGKPQGPPP 82
            G P    P G   P G P P G P+G         P+G    QGPP    PPG+   P P
Sbjct: 1340 GIPGASGPIGPGGPPGLPGPAG-PKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398

Query: 83   QGDKSRSPRSPPG----KPQGPPPQGGNQPQGPPPPPGKPQG 120
                 ++ RS  G    +     P GG         PG P G
Sbjct: 1399 IQMPKKTRRSVDGSRLMQEDEAIPTGG--------APGSPGG 1432


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  141 bits (355), Expect = 9e-34
 Identities = 119/356 (33%), Positives = 143/356 (40%), Gaps = 69/356 (19%)

Query: 36   PQGPS----PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKS-RS 89
            PQG +    P G     GPP PPG+   P   G    +G P PPG P    P G +    
Sbjct: 929  PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 988

Query: 90   PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQGDK- 147
             R  PG   GP  +G   P GPP P G P      G   P GPP    PQGPP   G+K 
Sbjct: 989  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 1048

Query: 148  ---SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-----PQGPPPQGGKK-------PQG 192
                + P  P G+     P G   P GPP   G+       G P Q G K       P G
Sbjct: 1049 VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPG 1108

Query: 193  PPPPGKPQGPP-------------PQG-------DKSRSSQSPPGK--PQGPPPQGGNQ- 229
            PP P  P G P             PQG       + +R    PPG    QG P   G + 
Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1168

Query: 230  ------PQGPPPPPGKPQGPP-PQGGNKPQGPP-------PPGKPQGPPAQGGSKSQSAR 275
                  P GPP PPG P+GP  P G + PQGPP       PPG+ +G P + GS      
Sbjct: 1169 ETGDVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGE-KGEPGESGSPGIQGE 1226

Query: 276  SPPGKPQGPPQQEGNN-------PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 324
                 P+G   ++G +       P GP  P G +  +    P G P  P  P +GG
Sbjct: 1227 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282



 Score =  140 bits (353), Expect = 2e-33
 Identities = 118/355 (33%), Positives = 133/355 (37%), Gaps = 52/355 (14%)

Query: 26   EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQG 84
            +  P    G        GG+ P GPP   G P    P G   P+GPP PPGK   P   G
Sbjct: 848  QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 907

Query: 85   DKSR-------SPRSPPG--KPQGPP----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
             +          P  PPG   PQG      P G     GPP PPG+   P   G    +G
Sbjct: 908  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 967

Query: 132  PP-PPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
             P PPG P    P G +     R  PG   GP  +G   P GPP P G P      G   
Sbjct: 968  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 1027

Query: 190  PQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQG----PPPQGGNQPQGPPPPPGK----- 239
            P GPP    PQGPP   G+K    +  P  P G      P G   P GPP   G+     
Sbjct: 1028 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKG 1087

Query: 240  PQGPPPQGGNK-------PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG--- 289
              G P Q G K       P GPP P  P G P   G+  +     P    G    EG   
Sbjct: 1088 EVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1147

Query: 290  -NNPQGP------PPPAGG-------NPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
             N P GP      P P+G         P  P  PP   P+GP  P     P  PP
Sbjct: 1148 FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG--PRGPAGPNGADGPQGPP 1200



 Score =  140 bits (352), Expect = 2e-33
 Identities = 121/358 (33%), Positives = 147/358 (41%), Gaps = 72/358 (20%)

Query: 32   IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKS--- 87
            + G   GP  +G   P GPP P G P      G   P GPP    PQGPP   G+K    
Sbjct: 992  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 1051

Query: 88   -RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGGNR-------PQGPPP 134
             + P  P G+     P G   P GPP   G+       G P Q G +       P GPP 
Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1111

Query: 135  PGKPQGPP-------------PQG-------DKSRSPRSPPGKP--QGPPPQGGNQ---- 168
            P  P G P             PQG       + +R    PPG    QG P   G +    
Sbjct: 1112 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171

Query: 169  ---PQGPPPPPGKPQGPP-PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP--PGKPQGP 222
               P GPP PPG P+GP  P G   PQGPP      GPP +  +   S SP   G+P   
Sbjct: 1172 DVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1230

Query: 223  PPQGGNQPQGPPPPPGKPQGPP----PQGGNKPQGPPP----PGKPQGPPAQGGSKSQSA 274
             P+G    +G    PG+P GPP    P G + P+G P     PG P GPP +GG + Q  
Sbjct: 1231 GPRGERGEKGESGQPGEP-GPPGPKGPTGDDGPKGNPGPVGFPGDP-GPPGEGGPRGQDG 1288

Query: 275  ----RSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 328
                R   G+P  P         GPP P G      +  PAG P    R  QGG+ ++
Sbjct: 1289 AKGDRGEDGEPGQPGSPGPTGENGPPGPLG------KRGPAGSPGSEGR--QGGKGAK 1338



 Score =  133 bits (334), Expect = 3e-31
 Identities = 112/342 (32%), Positives = 125/342 (36%), Gaps = 49/342 (14%)

Query: 27   ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-------------- 72
            E P    G    P P G    +G    PG P  P  QG     G P              
Sbjct: 771  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 830

Query: 73   -----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127
                 P G+     P+G   R PR   GK       GG+ P GPP   G P    P G  
Sbjct: 831  SGKSGPRGERGPTGPRG--QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888

Query: 128  RPQGPP-PPGKPQGPPPQGDKS----RSPRSPPGKPQGPPPQGGNQPQGP------PPPP 176
             P+GPP PPGK   P   G +     +    PPG P    PQG     GP      P PP
Sbjct: 889  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948

Query: 177  GKP--QGPPPQGGKK--PQGPPPPGKPQGPPPQGDKS-RSSQSPPGKPQGPPPQGGNQPQ 231
            G P  QG P   GK+     P PPG P    P G +     +  PG   GP  +G   P 
Sbjct: 949  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 1008

Query: 232  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG-- 289
            GPP P G P      G   P GPP    PQGPP   G K       P  P G    +G  
Sbjct: 1009 GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 1068

Query: 290  --NNPQGPPPPAG--------GNPQQPQAPPAGQPQGPPRPP 321
                P GPP  AG        G+P Q          GPP PP
Sbjct: 1069 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1110



 Score =  132 bits (331), Expect = 6e-31
 Identities = 119/366 (32%), Positives = 143/366 (39%), Gaps = 85/366 (23%)

Query: 38   GPSPQGGNK----PQGPPPPPGKPQGPP-PQGGNKPQGPP-------PPGKP-------- 77
            GPS + G      P GPP PPG P+GP  P G + PQGPP       PPG+         
Sbjct: 1162 GPSGEKGETGDVGPMGPPGPPG-PRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1220

Query: 78   ---QGPP----PQGDKSRSPRS-PPGKPQGPP----PQGGNQPQGPPPPPGKPQGPPPQG 125
               QG P    P+G++     S  PG+P GPP    P G + P+G P P G P  P P G
Sbjct: 1221 PGIQGEPGVKGPRGERGEKGESGQPGEP-GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPG 1279

Query: 126  GNRPQGPP----------PPGKPQGPPPQGDKSR----SPRSPPGKPQGPPPQGGNQPQG 171
               P+G             PG+P  P P G+         R P G P     QGG   +G
Sbjct: 1280 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKG 1339

Query: 172  PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP----PQGDKSRSSQSPPGKPQGPP---- 223
             P   G P    P G   P G P P   +G P     QG    + Q+ P  P GPP    
Sbjct: 1340 DPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1399

Query: 224  ---PQGGNQPQGPPP------PPGK-----------PQGPPPQGGNK----PQGPPPPGK 259
                 G    +G P       PPG+           PQG P Q G        GP  PG 
Sbjct: 1400 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1459

Query: 260  PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 319
            P G P   G K     + PG P+G    +G  P G P P G   +  Q  P   P+   R
Sbjct: 1460 PPGLPGPAGPKGAKGATGPGGPKGEKGVQG--PPGHPGPPG---EVIQPLPIQMPKKTRR 1514

Query: 320  PPQGGR 325
               G R
Sbjct: 1515 SVDGSR 1520



 Score =  123 bits (308), Expect = 3e-28
 Identities = 103/287 (35%), Positives = 120/287 (41%), Gaps = 32/287 (11%)

Query: 60   PPPQGGNKPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
            P  +G + P+GP     P G P  P   G+K +     PG P  P  QG     G P  P
Sbjct: 762  PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL--GVPGLPGYPGRQGPKGSLGFPGFP 819

Query: 116  GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
            G       +G +   GP     P GP  Q    R PR   GK       GG+ P GPP  
Sbjct: 820  GASGEKGARGLSGKSGPRGERGPTGPRGQ----RGPRGATGKSGAKGTSGGDGPHGPPGE 875

Query: 176  PGKPQGPPPQGGKKPQGPP-PPGKPQGPPPQGDKS----RSSQSPPGKPQGPPPQGGNQP 230
             G P    P G   P+GPP PPGK   P   G +     +    PPG P    PQG    
Sbjct: 876  RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 935

Query: 231  QGP------PPPPGKP--QGPPPQGGNKPQ--GPPPPGKP--QGPPAQGGSKSQSARSPP 278
             GP      P PPG P  QG P   G +     P PPG P   GP    G   +  R  P
Sbjct: 936  TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE--RGLP 993

Query: 279  GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-RP-PQG 323
            G   GP  +    P GPP PA G+P +  A  +G P GPP RP PQG
Sbjct: 994  GTAGGPGLKGNEGPSGPPGPA-GSPGERGAAGSGGPIGPPGRPGPQG 1039



 Score =  120 bits (300), Expect = 2e-27
 Identities = 128/400 (32%), Positives = 155/400 (38%), Gaps = 102/400 (25%)

Query: 23   VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQ----------GGNKPQG-- 70
            V+ E+      G+P     +G     GPP PPG P GP  Q          G   PQG  
Sbjct: 1079 VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG-PIGPVGQPGAAGADGEPGARGPQGHF 1137

Query: 71   -------------PPPPGKPQG-PPPQGDKSRS----PRSPPGKP--QGPP-PQGGNQPQ 109
                         PP P   QG P P G+K  +    P  PPG P  +GP  P G + PQ
Sbjct: 1138 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQ 1197

Query: 110  GPPP------PPGKPQGPPPQGGNRPQGPP----------------PPGKPQGPPPQG-- 145
            GPP       PPG+   P   G    QG P                 PG+P  P P+G  
Sbjct: 1198 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257

Query: 146  --DKSRSPRSPPGKP--QGPPPQGGNQPQ-------GPPPPPGKPQGPPPQGGKKPQGP- 193
              D  +    P G P   GPP +GG + Q       G    PG+P  P P G   P GP 
Sbjct: 1258 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPL 1317

Query: 194  ---PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP-----QGPPP 245
                P G P     QG K   ++  PG    P   G   P GP  P GKP     +G P 
Sbjct: 1318 GKRGPAGSPGSEGRQGGK--GAKGDPGAIGAP---GKTGPVGPAGPAGKPGPDGLRGLPG 1372

Query: 246  QGGNKPQGPP-------PPGKPQGPPAQGGSKSQS-ARSPPGKPQ-----GPPQQEG-NN 291
              G   QG P       PPG P GPP   G +  + A+   G P      GPP ++G   
Sbjct: 1373 SVGQ--QGRPGATGQAGPPG-PVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKG 1429

Query: 292  PQGPPPPAGGNPQQPQ--APPAGQPQGPPRPPQGGRPSRP 329
             +G P P G   Q+ +   P A  P GP  PP    P+ P
Sbjct: 1430 DRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGP 1469



 Score =  114 bits (285), Expect = 1e-25
 Identities = 114/361 (31%), Positives = 137/361 (37%), Gaps = 90/361 (24%)

Query: 36  PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS--P 93
           PQGP  +G   PQG P PPG+   P  QG   PQG   P   +GP  +      P S  P
Sbjct: 632 PQGP--KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP 689

Query: 94  PGKP--QGPPPQGGNQ----PQGPPPPPGKPQG--------------------------- 120
           PG P  +GPP   GNQ    PQGP   PG P+G                           
Sbjct: 690 PGHPGKEGPPGTKGNQGPSGPQGPLGYPG-PRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748

Query: 121 -------------PPPQGGNRPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163
                        P  +G + P+GP     P G P  P   G+K +     PG P  P  
Sbjct: 749 DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL--GVPGLPGYPGR 806

Query: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQGP 222
           QG   P+G    PG P     +G +   G   P   +GP  P+G   R  +   GK    
Sbjct: 807 QG---PKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ--RGPRGATGKSGAK 861

Query: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGK---PQGPPAQGGSKSQSARSPP 278
              GG+ P GPP   G P    P G   P+GPP PPGK   P  P  +G    Q    PP
Sbjct: 862 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 921

Query: 279 GKP-----------QGPPQQEGN-NPQGPPPPAG-----------GNPQQPQAPPAGQPQ 315
           G P            GP  + G+  P GPP   G           G+P  P AP    P 
Sbjct: 922 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 981

Query: 316 G 316
           G
Sbjct: 982 G 982



 Score =  112 bits (279), Expect = 6e-25
 Identities = 112/363 (30%), Positives = 135/363 (37%), Gaps = 80/363 (22%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
           + G P     +G    QG P PPG+       G   P+G P    P+G          P+
Sbjct: 563 LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-------LLGPK 615

Query: 92  SPPGKPQGPP----------PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
            PPG P GPP          P+G   PQG P PPG+   P  QG   PQG   P   +GP
Sbjct: 616 GPPGIP-GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674

Query: 142 PPQGDKSRSPRS--PPGKP--QGPPPQGGNQ-PQGPPPPPGKP-----------QGPPPQ 185
             +      P S  PPG P  +GPP   GNQ P GP  P G P           +G    
Sbjct: 675 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 734

Query: 186 GGKKPQGPPP-----------------PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
            G+K +   P                 PG      P+G K R+   P G P  P   G  
Sbjct: 735 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG--PTGDPGPPGLMGEK 792

Query: 229 QPQGPPPPPGKPQGPPPQG-----------GNK-------PQGPPPPGKPQGPPAQGGSK 270
              G P  PG P    P+G           G K         GP     P GP  Q G +
Sbjct: 793 GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 852

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAG-GNPQQPQAPPAGQPQGPPRPP-QGGRPSR 328
             + +S      G     G+ P GPP   G   PQ P   P   P+GPP PP + G P  
Sbjct: 853 GATGKSGAKGTSG-----GDGPHGPPGERGLPGPQGPNGFPG--PKGPPGPPGKDGLPGH 905

Query: 329 PPQ 331
           P Q
Sbjct: 906 PGQ 908



 Score =  103 bits (257), Expect = 2e-22
 Identities = 105/335 (31%), Positives = 124/335 (37%), Gaps = 72/335 (21%)

Query: 27  ESPSLIAGNPQGPSPQGGNKP---QGPPPPPGKP--QGPPPQGG--NKPQGPPPPGKP-- 77
           E   L+ G P    P G   P   QG P P G P  +GPP + G       P PPG    
Sbjct: 392 EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM 451

Query: 78  ----------------------------------QGPP-PQGDKSR-SPRSPPGKPQGPP 101
                                             +GPP P G   R  P   PG P    
Sbjct: 452 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 511

Query: 102 PQGGNQPQGPPPPPGKPQGPPPQGGNRPQ--GPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 159
             G   PQGP  P G   GPP + G R +       G P  P  +GD  R     PG P 
Sbjct: 512 ESGDLGPQGPRGPQGL-TGPPGKAGRRGRAGADGARGMPGDPGVKGD--RGFDGLPGLPG 568

Query: 160 GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP 219
               +G    QG P PPG+       G   P+G P    P+G           + PPG P
Sbjct: 569 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-------LLGPKGPPGIP 621

Query: 220 QGPP----------PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS 269
            GPP          P+G   PQG P PPG+   P  QG   PQG   P   +GP  + G 
Sbjct: 622 -GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGL 680

Query: 270 KSQ-SARSPPGKP--QGPPQQEGN-NPQGPPPPAG 300
                +  PPG P  +GPP  +GN  P GP  P G
Sbjct: 681 PGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 715



 Score =  100 bits (248), Expect = 2e-21
 Identities = 94/308 (30%), Positives = 117/308 (37%), Gaps = 31/308 (10%)

Query: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
           + Q  SP L  G      PQG   PQG   PPGK       G +  +G      P  P  
Sbjct: 501 LGQPGSPGL-KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG-----MPGDPGV 554

Query: 83  QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142
           +GD+       PG P     +G    QG P PPG+       G   P+G P    P+G  
Sbjct: 555 KGDRGFD--GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG-- 610

Query: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGKKPQGPPPPGKP 199
                   P+ PPG P  P  +G + PQGP     P G+P  P  QG    QG P P   
Sbjct: 611 -----LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGA 665

Query: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259
            GP   G+K      P GKP  P   G + P G P   G P     QG + PQGP     
Sbjct: 666 IGP--HGEKG-----PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 718

Query: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEGN----NPQGPPPPAGGNPQQPQAPPAGQ-- 313
           P+G     G +            G P  +G+      +G     G   +     P G+  
Sbjct: 719 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 778

Query: 314 PQGPPRPP 321
           P G P PP
Sbjct: 779 PTGDPGPP 786



 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 101/333 (30%), Positives = 125/333 (37%), Gaps = 57/333 (17%)

Query: 38  GPSPQGGNKPQGPPPPPGK-PQGPPPQGGNKPQGPP----PPGKPQGPPPQGDKSRSPRS 92
           GP    G K +     PG   +GPP      P+GP     PPG    P P GD     R 
Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPG-----PEGPAGLIGPPGIQGNPGPVGDPGE--RG 429

Query: 93  PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--GGNRPQGPPPPGKP------------ 138
           PPG+   P   G       P PPG     P +   G   +GP    +             
Sbjct: 430 PPGRAGLPGSDGA------PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 483

Query: 139 --QGPP-PQGDKSR-SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP 194
             +GPP P G   R  P   PG P      G   PQGP  P G   GPP + G++ +   
Sbjct: 484 ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT-GPPGKAGRRGRAGA 542

Query: 195 PP--GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK-----------PQ 241
               G P  P  +GD  R     PG P     +G    QG P PPG+           P+
Sbjct: 543 DGARGMPGDPGVKGD--RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 600

Query: 242 GPPPQGGNK----PQGPPP-PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 296
           G P + G +    P+GPP  PG P      G    + +  P G+P  P QQ     QG P
Sbjct: 601 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660

Query: 297 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
            P G      +  P G+P  P  P   G P  P
Sbjct: 661 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 693



 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 105/331 (31%), Positives = 134/331 (40%), Gaps = 47/331 (14%)

Query: 29  PSLIAGNPQGPS-PQGGNKP---QGPPPPPGKP--QGPPPQGG--NKPQGPPPPGKPQGP 80
           P ++   P GP  P G   P   QG P P G P  +GPP + G       P PPG     
Sbjct: 393 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 452

Query: 81  PPQ-----GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135
           P +     GDK     +   + Q    Q     +GPP P G    P P G  +P  P   
Sbjct: 453 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG--QPGSPGLK 510

Query: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGPPPQGGKKPQGPP 194
           G+     PQG     PR P G   GPP + G + + G     G P  P  +G +   G P
Sbjct: 511 GESGDLGPQG-----PRGPQGLT-GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 564

Query: 195 P-PGKP--------QG-PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQGP 243
             PG+         QG P P G+           P+G P + G +   GP  PPG P  P
Sbjct: 565 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 624

Query: 244 PPQGGNKPQGPP----PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP--- 296
             +G + PQGP     P G+P GPP Q G+        P    GP  ++G  PQG P   
Sbjct: 625 GVRGMDGPQGPKGSLGPQGEP-GPPGQQGTPGTQGLPGPQGAIGPHGEKG--PQGKPGLP 681

Query: 297 --PPAGGNPQQP--QAPPAGQPQGPPRPPQG 323
             P + G P  P  + PP  +    P  PQG
Sbjct: 682 GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 58/234 (24%), Positives = 74/234 (31%), Gaps = 44/234 (18%)

Query: 124 QGGNR--PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 181
           +GG R  PQ   P    + P  Q  +   P++   +PQ  P +       PP       G
Sbjct: 229 EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQ--EPQSQPTESLYYDYEPPYYDVMTTG 286

Query: 182 PPPQGGKKPQGPPPPGKPQGP------PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235
             P         P PG+ +        PP  ++    Q PP   +    + G     PP 
Sbjct: 287 TTPD-----YQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPE 341

Query: 236 PP-------------GKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK-P 281
            P                 GP         G        GP    G K + A   PG   
Sbjct: 342 GPYDYTYGYGDDYREETELGPALSAETAHSG----AAAHGPRGLKGEKGEPAVLEPGMLV 397

Query: 282 QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP--QGPP----RPPQGGRPSRP 329
           +GPP  EG      PP   GNP      P G P  +GPP     P   G P  P
Sbjct: 398 EGPPGPEGPAGLIGPPGIQGNP-----GPVGDPGERGPPGRAGLPGSDGAPGPP 446



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 12/70 (17%)

Query: 36   PQGPSPQGGNK----PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
            PQG   Q G        GP  P G P  P P G    +G   PG P+G        +  +
Sbjct: 1436 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG-------EKGVQ 1488

Query: 92   SPPGKPQGPP 101
             PPG P GPP
Sbjct: 1489 GPPGHP-GPP 1497



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 24/102 (23%)

Query: 34   GNPQGPSPQGGNKPQGPPPPPGKPQGPP-------PQGGNKPQGPP----PPGKPQGPPP 82
            G P    P G   P G P P G P+G         P+G    QGPP    PPG+   P P
Sbjct: 1447 GIPGASGPIGPGGPPGLPGPAG-PKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505

Query: 83   QGDKSRSPRSPPG----KPQGPPPQGGNQPQGPPPPPGKPQG 120
                 ++ RS  G    +     P GG         PG P G
Sbjct: 1506 IQMPKKTRRSVDGSRLMQEDEAIPTGG--------APGSPGG 1539


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score =  140 bits (353), Expect = 2e-33
 Identities = 112/351 (31%), Positives = 135/351 (38%), Gaps = 54/351 (15%)

Query: 5   LLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP--PPPGKPQGPPP 62
           L    +  L S  N + D      P L         P GG      P  PP G  + P P
Sbjct: 103 LFQAGMPKLRSTANRDNDSGGSRPPLL---------PPGGRSTSAKPFSPPSGPGRFPVP 153

Query: 63  QGGNKPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPP-QGGNQPQGPPPPPGKPQG 120
             G++  GPP P + + PPP+ D    P S PP  P  P P Q     +G PP PG P+ 
Sbjct: 154 SPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-----------PP-------GKPQGPP 162
           P P     P  PP PG        G   +SP S           PP        KP  PP
Sbjct: 213 PSPG----PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP 268

Query: 163 PQGGNQPQ-----GPPPPPGK-----PQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS 212
           P  GN+P       PPPPP       P  P P    +   PPPP    GPPP    S  +
Sbjct: 269 PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGSK 270
              P  PQ       + P  P P    P  PPP     P    PPG+  P  PP      
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
             ++R+ P  PQ P +   ++P+  P P    P  P  P AG P  PP PP
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDRPSAGAP--PPPPP 433



 Score =  116 bits (291), Expect = 2e-26
 Identities = 108/360 (30%), Positives = 140/360 (38%), Gaps = 51/360 (14%)

Query: 9   ALLA-LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK 67
           ALL+ +S  + L + V+ + S  ++   P+G    GG    G     G   G    G   
Sbjct: 35  ALLSDISKGKKLKKTVTNDRSAPIL-DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG 93

Query: 68  PQGPPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPP 123
             GPP  G   +   P  +   +R   S   +P   PP G +    P  PP G  + P P
Sbjct: 94  GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153

Query: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPP-QGGNQPQGPPPPPGKPQG 181
             G+R  GPP P + + PPP+ D    P S PP  P  P P Q     +G PP PG P+ 
Sbjct: 154 SPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212

Query: 182 PPPQGGKKPQGPPPPGKPQG-----------PPPQGDKSRSSQSPP----------GKPQ 220
           P P       GP PP  P               P    S  S  PP           KP 
Sbjct: 213 PSP-------GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265

Query: 221 GPPPQGGNQPQ-----GPPPPPGK-----PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
            PPP  GN+P       PPPPP       P  P P   ++   PPPP    GPP    S 
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
           S +  +    P+ P +    +   PP P+ G       PP+ +P  P R P G     PP
Sbjct: 326 SGNDET----PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score =  140 bits (353), Expect = 2e-33
 Identities = 112/351 (31%), Positives = 135/351 (38%), Gaps = 54/351 (15%)

Query: 5   LLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP--PPPGKPQGPPP 62
           L    +  L S  N + D      P L         P GG      P  PP G  + P P
Sbjct: 103 LFQAGMPKLRSTANRDNDSGGSRPPLL---------PPGGRSTSAKPFSPPSGPGRFPVP 153

Query: 63  QGGNKPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPP-QGGNQPQGPPPPPGKPQG 120
             G++  GPP P + + PPP+ D    P S PP  P  P P Q     +G PP PG P+ 
Sbjct: 154 SPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212

Query: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-----------PP-------GKPQGPP 162
           P P     P  PP PG        G   +SP S           PP        KP  PP
Sbjct: 213 PSPG----PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP 268

Query: 163 PQGGNQPQ-----GPPPPPGK-----PQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS 212
           P  GN+P       PPPPP       P  P P    +   PPPP    GPPP    S  +
Sbjct: 269 PPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGSK 270
              P  PQ       + P  P P    P  PPP     P    PPG+  P  PP      
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
             ++R+ P  PQ P +   ++P+  P P    P  P  P AG P  PP PP
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRP----PLPPDRPSAGAP--PPPPP 433



 Score =  116 bits (291), Expect = 2e-26
 Identities = 108/360 (30%), Positives = 140/360 (38%), Gaps = 51/360 (14%)

Query: 9   ALLA-LSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK 67
           ALL+ +S  + L + V+ + S  ++   P+G    GG    G     G   G    G   
Sbjct: 35  ALLSDISKGKKLKKTVTNDRSAPIL-DKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFG 93

Query: 68  PQGPPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPP 123
             GPP  G   +   P  +   +R   S   +P   PP G +    P  PP G  + P P
Sbjct: 94  GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVP 153

Query: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPP-QGGNQPQGPPPPPGKPQG 181
             G+R  GPP P + + PPP+ D    P S PP  P  P P Q     +G PP PG P+ 
Sbjct: 154 SPGHR-SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQ 212

Query: 182 PPPQGGKKPQGPPPPGKPQG-----------PPPQGDKSRSSQSPP----------GKPQ 220
           P P       GP PP  P               P    S  S  PP           KP 
Sbjct: 213 PSP-------GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265

Query: 221 GPPPQGGNQPQ-----GPPPPPGK-----PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
            PPP  GN+P       PPPPP       P  P P   ++   PPPP    GPP    S 
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
           S +  +    P+ P +    +   PP P+ G       PP+ +P  P R P G     PP
Sbjct: 326 SGNDET----PRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score =  139 bits (351), Expect = 3e-33
 Identities = 97/255 (38%), Positives = 115/255 (45%), Gaps = 34/255 (13%)

Query: 36  PQGPSP-QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94
           P GP P Q G KP  PPPPP + Q  PP     PQ PPP   P   PP   +    + PP
Sbjct: 46  PMGPGPGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPPHQPPPHPQPHQQQQPP 100

Query: 95  GKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151
                PPPQ  ++P   QGP P PG    PP      P  PP  G P G  P    +  P
Sbjct: 101 -----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPP 155

Query: 152 ---RSPPGKPQGPPPQGG-----NQPQGPPPPPG--KPQGPPPQGGKKPQGPPPPGKPQG 201
               +PPG P   PP  G      Q  GPPPPP      GP P+ G  P GP     P G
Sbjct: 156 AVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGG 215

Query: 202 PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 261
           P P G    S  +P G P+ PP +GG +P+G     G+ Q  PP      QG PPPG P 
Sbjct: 216 PKPGGGPGLS--TPGGHPK-PPHRGGGEPRG-----GR-QHHPPYHQQHHQG-PPPGGPG 265

Query: 262 GPPAQGGSKSQSARS 276
           G   +  S S+  ++
Sbjct: 266 GRSEEKISDSEGFKA 280



 Score =  134 bits (338), Expect = 9e-32
 Identities = 97/254 (38%), Positives = 111/254 (43%), Gaps = 44/254 (17%)

Query: 88  RSPRSPPGK-------PQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ 139
           RSP  PPG        P GP P Q G +P  PPPPP + Q  PP     PQ PPP   P 
Sbjct: 32  RSP--PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPP 84

Query: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGKKPQGPP-- 194
             PP   +    + PP     PPPQ  ++P   QGP P PG    PP      P  PP  
Sbjct: 85  HQPPPHPQPHQQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS 139

Query: 195 --PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG-----NQPQGPPPPPGKPQGPPPQG 247
             PPG   GP P    + +S +PPG P   PP  G      Q  GPPPPP    GP P  
Sbjct: 140 GAPPGSGPGPTPTPPPAVTS-APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG- 197

Query: 248 GNKPQGPPPPGKPQGPPAQGGSKSQSAR--SPPGKPQGPPQQEGNNPQGPP---PPAGGN 302
              P+  P PG P+G    GG K       S PG    PP + G  P+G     PP   +
Sbjct: 198 ---PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPY--H 252

Query: 303 PQQPQAPPAGQPQG 316
            Q  Q PP G P G
Sbjct: 253 QQHHQGPPPGGPGG 266



 Score =  124 bits (311), Expect = 1e-28
 Identities = 101/269 (37%), Positives = 111/269 (41%), Gaps = 50/269 (18%)

Query: 48  QGPPPPPGKPQGPPPQG-GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 106
           + PPP  G  Q   P G G    GP PP  P  PPP   + + P      PQ PPPQ   
Sbjct: 32  RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPP--PPPHQQQQQPP------PQQPPPQ--- 80

Query: 107 QPQGPPPPPGKPQ-------GPPPQGGNRP---QGP-PPPGKPQGPPPQGDKSRSPRSPP 155
           QP    PPP  PQ        PPPQ  ++P   QGP P PG    PP     S  P +PP
Sbjct: 81  QPPPHQPPP-HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP--ASSSAPPATPP 137

Query: 156 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215
               G PP  G  P  P PPP     PP   G  P  PP  G P  PP  G        P
Sbjct: 138 --TSGAPPGSGPGPT-PTPPPAVTSAPP---GAPPPTPPSSGVPTTPPQAG-------GP 184

Query: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPAQGGSKSQ 272
           P  P   P  G    QG  P PG P+G    GG KP G P    PG    PP +GG +  
Sbjct: 185 PPPPAAVPGPGPGPKQG--PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE-- 240

Query: 273 SARSPPGKPQGPPQQEGNNPQGPPPPAGG 301
               P G  Q  P     + QGPPP   G
Sbjct: 241 ----PRGGRQHHPPYHQQHHQGPPPGGPG 265



 Score =  119 bits (297), Expect = 5e-27
 Identities = 95/249 (38%), Positives = 105/249 (42%), Gaps = 51/249 (20%)

Query: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 159
           PP  G NQ +GP  P     GP P     P  PPPP + Q  PP       P+ PP  PQ
Sbjct: 35  PPGMGLNQNRGPMGPGPGQSGPKP-----PIPPPPPHQQQQQPP-------PQQPP--PQ 80

Query: 160 GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP---QGP-PPPGKPQGPPPQGDKSRSSQSP 215
            PPP     P  P P   +   PPPQ   KP   QGP P PG    PP       SS +P
Sbjct: 81  QPPPH--QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPA------SSSAP 132

Query: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-----GKPQGPPAQGGSK 270
           P  P   P  G     GP P P     PPP   + P G PPP     G P  PP  GG  
Sbjct: 133 PATP---PTSGAPPGSGPGPTPT----PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185

Query: 271 SQSARSP---PGKPQGP---PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR---PP 321
              A  P   PG  QGP     + G  P GP P  GG P    + P G P+ P R    P
Sbjct: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP--GGGP--GLSTPGGHPKPPHRGGGEP 241

Query: 322 QGGRPSRPP 330
           +GGR   PP
Sbjct: 242 RGGRQHHPP 250



 Score =  102 bits (255), Expect = 4e-22
 Identities = 75/212 (35%), Positives = 88/212 (41%), Gaps = 23/212 (10%)

Query: 17  QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPP-----PGKPQGPPPQGGNKPQGP 71
           Q   +   Q+  P     +   P PQ   + Q PPPP     P   QGP P  G    G 
Sbjct: 67  QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG---VGS 123

Query: 72  PPPGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGG 126
            PP     PP     S + P S PG    PPP   + P G PPP     G P  PP  GG
Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGG 183

Query: 127 NRPQGPPPPGKPQGPPPQGDKSRSPRSPPG--KPQGPPPQGG---NQPQGPPPPPGKPQG 181
                PPPP    GP P   +   P  P G   P GP P GG   + P G P PP +  G
Sbjct: 184 ----PPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHR-GG 238

Query: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213
             P+GG++   P      QGPPP G   RS +
Sbjct: 239 GEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEE 270



 Score =  102 bits (254), Expect = 5e-22
 Identities = 74/201 (36%), Positives = 81/201 (40%), Gaps = 45/201 (22%)

Query: 149 RSPRSPPGK-------PQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
           RSP  PPG        P GP P Q G +P  PPPPP + Q  PP     PQ PPP   P 
Sbjct: 32  RSP--PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPP 84

Query: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPPPP 257
             PP   +    Q PP     PPPQ  ++P   QGP P PG    PP      P  PP  
Sbjct: 85  HQPPPHPQPHQQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS 139

Query: 258 GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP---AGGNPQQ------PQA 308
           G P G             S PG    PP    + P G PPP   + G P        P  
Sbjct: 140 GAPPG-------------SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186

Query: 309 PPAGQPQGPPRPPQGGRPSRP 329
           PPA  P   P P QG  P  P
Sbjct: 187 PPAAVPGPGPGPKQGPGPGGP 207



 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 74/195 (37%), Positives = 82/195 (42%), Gaps = 36/195 (18%)

Query: 161 PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGK------PQGPPPQGDKSRSSQS 214
           PP  G NQ +GP  P     GP   G K P  PPPP +      PQ PPPQ         
Sbjct: 35  PPGMGLNQNRGPMGP-----GPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQ---QPPPHQ 86

Query: 215 PPGKPQ-------GPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPP----PPGKP 260
           PP  PQ        PPPQ  ++P   QGP P PG    PP      P  PP    PPG  
Sbjct: 87  PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSG 146

Query: 261 QGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA---GQPQGP 317
            GP         SA  PPG P  PP    +     PP AGG P  P A P    G  QGP
Sbjct: 147 PGPTPTPPPAVTSA--PPGAP--PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGP 202

Query: 318 -PRPPQGGRPSRPPQ 331
            P  P+GG+    P+
Sbjct: 203 GPGGPKGGKMPGGPK 217



 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 54/156 (34%), Positives = 60/156 (38%), Gaps = 36/156 (23%)

Query: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-- 260
           PP G     ++ P G   GP   G   P  PPPP  + Q PPPQ        PPP +P  
Sbjct: 34  PPPGMGLNQNRGPMGP--GPGQSGPKPPIPPPPPHQQQQQPPPQ-------QPPPQQPPP 84

Query: 261 --------------QGPPAQGGSKSQSARSP---PGKPQGPPQQEGNNPQGPP----PPA 299
                           PP Q  SK   A+ P   PG    PP      P  PP    PP 
Sbjct: 85  HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG 144

Query: 300 GGNPQQPQAPPA--GQPQG--PPRPPQGGRPSRPPQ 331
            G    P  PPA    P G  PP PP  G P+ PPQ
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  136 bits (343), Expect = 2e-32
 Identities = 124/353 (35%), Positives = 142/353 (40%), Gaps = 76/353 (21%)

Query: 33   AGNPQGPS----PQGGNKPQGPPPPPGKPQ-----GPPPQGGNK-PQGPPPPGKPQGPP- 81
            A  PQGP+    P+G    QGPP   G P      GPP   GN  P GPP P    GP  
Sbjct: 871  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930

Query: 82   PQGDKS----------RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGG 126
             +GD            + P  PPG+   P   G +  +GPP P G        G P Q G
Sbjct: 931  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG 990

Query: 127  NR--PQGPPP---PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP-- 179
             R  P  P P   PGK   P   GD     R PPG P GPP   G  P G P   G P  
Sbjct: 991  ERGFPGLPGPSGEPGKQGAPGASGD-----RGPPG-PVGPPGLTG--PAGEPGREGSPGA 1042

Query: 180  QGPPPQGGKK--------------PQGPPPPGKPQGPPP---QGDKSRSSQSPPGKPQGP 222
             GPP + G                P  P PPG P    P   QGD+  +    P  P GP
Sbjct: 1043 DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1102

Query: 223  PPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQG-------PPPPGKPQGPPAQGGSKSQSA 274
                G Q PQGP    G+   P  +G    +G       P PPG      A G +     
Sbjct: 1103 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1162

Query: 275  RSPPGKPQGPPQQEGNN----PQGPPPPAGGNPQQPQAPPAGQPQ--GPPRPP 321
            R PPG P GP  ++G N    P GPP P G   +  +  PAG P   GPP PP
Sbjct: 1163 RGPPG-PVGPSGKDGANGIPGPIGPPGPRG---RSGETGPAGPPGNPGPPGPP 1211



 Score =  127 bits (319), Expect = 1e-29
 Identities = 136/407 (33%), Positives = 156/407 (38%), Gaps = 121/407 (29%)

Query: 33   AGNPQGPS-PQGGNKPQGPPPPPG-----KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
            A  P GP+ P G    QG P P G      P GPP +GG KP     PG+   P   G  
Sbjct: 640  AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG-KPGDQGVPGEAGAPGLVGP- 697

Query: 87   SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP----PPGKPQGPP 142
             R  R  PG+   P  QG    QGP   PG P    P+G + P GPP    PPG  QG P
Sbjct: 698  -RGERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMP 752

Query: 143  ----------PQGDKS----RSPRSPPGK--------PQGPP-PQGGNQPQGPPPPPGK- 178
                      P+GD+     + P   PGK        P GPP P G N  +G   PPG  
Sbjct: 753  GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 812

Query: 179  ----------------PQGP-----PP-------------QGGKK-------PQGPPPPG 197
                            P GP     PP             + G+K       PQGP    
Sbjct: 813  GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872

Query: 198  KPQGPP----PQGDKSRSSQSPPGKPQGPP------PQGGNQPQGPPPPPGKPQGPPPQG 247
             PQGP     P+G  +R +Q PPG    P       P G N   GPP PPG      P+G
Sbjct: 873  GPQGPTGVTGPKG--ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930

Query: 248  GNKPQGPP----PPGK--PQGPPAQGGSKS----QSARSPPGKPQGPPQQEG-------N 290
                 GPP     PG   P GPP + G         A  PPG PQG   Q G        
Sbjct: 931  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG-PQGLAGQRGIVGLPGQR 989

Query: 291  NPQGPP--PPAGGNPQQPQAPPAGQPQGPPRP--PQG-----GRPSR 328
              +G P  P   G P +  AP A   +GPP P  P G     G P R
Sbjct: 990  GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036



 Score =  122 bits (305), Expect = 6e-28
 Identities = 131/408 (32%), Positives = 153/408 (37%), Gaps = 97/408 (23%)

Query: 13  LSSAQNLNEDVSQEESPSL-----IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK 67
           L+  +  N D  +   P L     + G P    PQG   P G P   G+P  P PQG   
Sbjct: 538 LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 597

Query: 68  PQGP---PPPGKPQGPPPQGDKSRSPRSP-----PGKP-----QGPP----PQGGNQPQG 110
             G    P P    G P +  +   P +P     PGK       GPP    P G    QG
Sbjct: 598 QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 657

Query: 111 PPPPPG-----KPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
            P P G      P GPP +GG +P     PG+   P   G   R  R  PG+   P  QG
Sbjct: 658 APGPSGFQGLPGPPGPPGEGG-KPGDQGVPGEAGAPGLVGP--RGERGFPGERGSPGAQG 714

Query: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPP----PPGKPQGPP----------PQGDKS-- 209
               QGP   PG P    P+G   P GPP    PPG  QG P          P+GD+   
Sbjct: 715 ---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDV 770

Query: 210 --RSSQSPPGK--------PQGPP-PQGGNQPQG---PPPPPGKPQGPPPQGGNKPQGPP 255
             +  +  PGK        P GPP P G N  +G   PP P G        G     GPP
Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830

Query: 256 PPGKPQGPPA---QGGSKSQ----------SARSPPGK-----PQGPPQQEG----NNPQ 293
            P    GPP    Q G+K +           A  P G      PQGP    G       Q
Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890

Query: 294 GPP-----PPAGGNPQQPQAPPAGQPQGPPRP-----PQGGR-PSRPP 330
           GPP     P A G    P +     P GPP P     P+G R  S PP
Sbjct: 891 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938



 Score =  120 bits (302), Expect = 1e-27
 Identities = 111/356 (31%), Positives = 136/356 (38%), Gaps = 71/356 (19%)

Query: 36  PQGP-SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKSRSPRSP 93
           P+GP  P G   PQG    PG+P  P   G   P+GPP PPGKP      GD   + +  
Sbjct: 208 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP------GDDGEAGKPG 261

Query: 94  PGKPQGPP-PQGGNQPQGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150
               +GPP PQG     G P  PG    +G P   G + +   P  K +   P  + S  
Sbjct: 262 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG 321

Query: 151 PRSPPGKP-----QGPPPQGGNQ-------PQGPPPPPGKPQGPP------------PQG 186
           P  P G P      GP    G +       P GPP P G   GP             P G
Sbjct: 322 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 381

Query: 187 GKKPQGPP----PPGKPQGPPPQGDK----------SRSSQSPPG--------KPQGPP- 223
            + P+G       PG P  P P G            ++ S   PG         P+GPP 
Sbjct: 382 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 441

Query: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ-SARSPPGK-- 280
           PQG   P GP    G+P     +G   P+G P P  PQG P   G + +  AR  PG   
Sbjct: 442 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501

Query: 281 PQGPPQQEG----------NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326
           P GPP + G          +   GP    G       A P G    P RP + G P
Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557



 Score =  120 bits (301), Expect = 2e-27
 Identities = 97/305 (31%), Positives = 117/305 (38%), Gaps = 41/305 (13%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---- 79
            S ++ P    G+   P   G    QGP  PPG+   P   G +  +GPP P    G    
Sbjct: 923  SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI 982

Query: 80   ---PPPQGDKS----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNRPQ 130
               P  +G++       P   PGK   P   G   P GP  PPG   P G P + G+ P 
Sbjct: 983  VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS-PG 1041

Query: 131  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190
               PPG+      +GD+  +     G P  P P G   P GP    G       QG   P
Sbjct: 1042 ADGPPGRDGAAGVKGDRGET--GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099

Query: 191  QGPPPPGKPQGPP-PQGDKSRSS----------------QSPPGKPQGPPPQGGNQPQGP 233
             GP      QGP  P+GDK  +                 Q  PG P     QG + P GP
Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159

Query: 234  PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
              P G P    P G +   G P P  P GP  +G S       PPG P GPP      P 
Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPGPIGPPGP--RGRSGETGPAGPPGNP-GPP-----GPP 1211

Query: 294  GPPPP 298
            GPP P
Sbjct: 1212 GPPGP 1216



 Score =  118 bits (295), Expect = 8e-27
 Identities = 114/336 (33%), Positives = 130/336 (38%), Gaps = 65/336 (19%)

Query: 34  GNPQGPSPQG--------GNKPQGPPPPPGKPQGPPPQGGN----------KPQGPPPPG 75
           G    P P+G        GN   GPP PPG P GPP  GGN          +  G    G
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNP--GPPGPPGPP-GPPGLGGNFAAQMAGGFDEKAGGAQLG 197

Query: 76  KPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP- 133
             QGP  P G     PR PPG    P PQG    QG P  PG+P    P G   P+GPP 
Sbjct: 198 VMQGPMGPMG-----PRGPPGPAGAPGPQGF---QGNPGEPGEPGVSGPMG---PRGPPG 246

Query: 134 PPGKPQGPPPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKP--QGPPPQGGKKP 190
           PPGKP      GD   + +      +GPP PQG     G P  PG    +G P   G K 
Sbjct: 247 PPGKP------GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 300

Query: 191 QGPPP--------PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ----PQGPPPPPG 238
           +   P        PG+   P P G +    +     P G     GN     P GPP P G
Sbjct: 301 EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 360

Query: 239 KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP-PQQEGNNP--QGP 295
              GP   G    +G   P   +GP       +Q  R  PG P  P P     NP   G 
Sbjct: 361 PAGGPGFPGAPGAKGEAGPTGARGPEG-----AQGPRGEPGTPGSPGPAGASGNPGTDGI 415

Query: 296 PPPAG--GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           P   G  G P    AP    P+GPP P     P  P
Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 451



 Score =  114 bits (286), Expect = 9e-26
 Identities = 109/334 (32%), Positives = 131/334 (39%), Gaps = 57/334 (17%)

Query: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG----PP 81
           EE      G P G  P G   P G    PG    P   G   P+G P    P G      
Sbjct: 487 EEGKRGARGEPGGVGPIG---PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 543

Query: 82  PQGDKSR-------SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP-- 132
             GD  R         R   G+P    PQG   P G P   G+P  P PQG     G   
Sbjct: 544 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 603

Query: 133 -PPPGKPQGPPPQGDKSRSPRSP-----PGK-----PQGPP----PQGGNQPQGPPPPPG 177
            P P    G P +  +   P +P     PGK       GPP    P G    QG P P G
Sbjct: 604 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663

Query: 178 -----KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG 232
                 P GPP +GG KP     PG+   P   G   R  +  PG+   P  QG    QG
Sbjct: 664 FQGLPGPPGPPGEGG-KPGDQGVPGEAGAPGLVG--PRGERGFPGERGSPGAQG---LQG 717

Query: 233 PPPPPGKPQGPPPQGGNKPQGPP----PPGKPQGPPAQGGSKS----QSARSPPGK--PQ 282
           P   PG P    P+G + P GPP    PPG  QG P + G+      +  R   G+  P+
Sbjct: 718 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDVGEKGPE 776

Query: 283 GPPQQEG----NNPQGPPPPAGGNPQQPQAPPAG 312
           G P ++G      P GPP PAG N ++ +  P G
Sbjct: 777 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810



 Score =  111 bits (278), Expect = 8e-25
 Identities = 115/379 (30%), Positives = 139/379 (36%), Gaps = 100/379 (26%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP---------QGPP-PPGKPQGPPPQ 83
           GN   P P G   P GP   PG P  P  +G   P         QGP   PG P  P P 
Sbjct: 345 GNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA 404

Query: 84  GDK----------SRSPRSPPG--------KPQGPP-PQGGNQPQGPPPPPGKPQGPPPQ 124
           G            ++     PG         P+GPP PQG   P GP    G+P     +
Sbjct: 405 GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 464

Query: 125 GGNRPQGPPPPGKPQGPP-PQGDKSR----------SPRSPPGK---------------- 157
           G   P+G P P  PQG P P G++ +           P  PPG+                
Sbjct: 465 GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 524

Query: 158 -PQGPP----------PQGGNQPQGPPPPPGKP-----QGPP----PQGGKKPQGPP-PP 196
            P+G P          P+G N   G P  PG P      G P    PQG   P G P   
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584

Query: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN-QP-----QGPPPPPGKPQGPPPQGGNK 250
           G+P  P PQG + +     PG    P P+G N +P     +G P  PG    P   G   
Sbjct: 585 GRPGPPGPQGARGQ-----PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 639

Query: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAG--------- 300
             GPP P  P G   + G+   S       P GPP + G    QG P  AG         
Sbjct: 640 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699

Query: 301 --GNPQQPQAPPAGQPQGP 317
             G P +  +P A   QGP
Sbjct: 700 ERGFPGERGSPGAQGLQGP 718



 Score =  111 bits (278), Expect = 8e-25
 Identities = 112/349 (32%), Positives = 134/349 (38%), Gaps = 64/349 (18%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG----PPPQG 84
           P+  +GNP      G     G P   G P  P P+G   PQG   P  P+G    P   G
Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG 462

Query: 85  DK-SRSPRSPPGK--PQGPP-------------PQGGNQPQGPPPPPGKP--QGPPPQGG 126
            K  + P+  PG   PQG P               GG  P GPP   G P  +G P Q G
Sbjct: 463 FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDG 522

Query: 127 -NRPQGPPPPGKPQG----PPPQGDKSR-------SPRSPPGKPQGPPPQGGNQPQGPPP 174
              P+G P    P G        GD  R         R   G+P    PQG   P G P 
Sbjct: 523 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 582

Query: 175 PPGKPQGPPPQGGKKPQG----PPPPGKPQGPPPQGDKSRSSQSPPGKP--QGPPPQGGN 228
             G+P  P PQG +   G    P P G    P   G+K       PG P  +G P + G 
Sbjct: 583 EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGE 637

Query: 229 QPQGPPPPPGKPQG-------PPPQGGNKPQGPPPP----GKP--QGPPAQGGSKS---- 271
                PP P  P G       P P G     GPP P    GKP  QG P + G+      
Sbjct: 638 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 697

Query: 272 QSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP--QGPP 318
           +  R  PG+   P  Q    P+G P   G +  +  + PAG P  QGPP
Sbjct: 698 RGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746



 Score =  111 bits (277), Expect = 1e-24
 Identities = 102/330 (30%), Positives = 129/330 (39%), Gaps = 42/330 (12%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGK-----PQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
           + G    P   G   P GP   PG+     P G     GN   G P P  P GP      
Sbjct: 307 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN--DGQPGPAGPPGPVGPAGG 364

Query: 87  SRSPRSPPGKPQGPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
              P +P  K +  P     P+G   P+G P  PG P GP    GN      P  K    
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSP-GPAGASGNPGTDGIPGAKGSAG 423

Query: 142 PPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
            P    + +P  P   P+GPP PQG   P GP    G+P     +G + P+G P P  PQ
Sbjct: 424 AP--GIAGAPGFPG--PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479

Query: 201 GPP-PQGDKSRSSQ----------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
           G P P G++ +              PPG+   P  +G     G   P G P    P G  
Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 539

Query: 250 KPQG----PPPPGKPQGPPAQGGSKSQSARSPPGK--PQGPPQQEGNNPQGPPPPAGGNP 303
            P+G    P  PG+P  P A+G +       P GK  P G P ++G    GPP P G   
Sbjct: 540 GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR--PGPPGPQG-AR 596

Query: 304 QQPQAPPAGQPQG----PPRPPQGGRPSRP 329
            QP       P+G    P +  + G P  P
Sbjct: 597 GQPGVMGFPGPKGANGEPGKAGEKGLPGAP 626



 Score =  100 bits (250), Expect = 1e-21
 Identities = 92/288 (31%), Positives = 110/288 (38%), Gaps = 40/288 (13%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
            PS   G    P   G   P GP  PPG   P G P + G+ P    PPG+      +GD+
Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS-PGADGPPGRDGAAGVKGDR 1058

Query: 87   SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQG 145
              +     G P  P P G   P GP    G       QG   P GP      QGP  P+G
Sbjct: 1059 GET--GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116

Query: 146  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP----PQGGKKPQGPPPPGKPQG 201
            DK  +    PG+      +G    QG P PPG P G      P G   P+GPP P  P G
Sbjct: 1117 DKGEA--GEPGERGLKGHRGFTGLQGLPGPPG-PSGDQGASGPAGPSGPRGPPGPVGPSG 1173

Query: 202  -------PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP--Q 252
                   P P G      +S    P GPP   G  P GPP PPG         G  P  +
Sbjct: 1174 KDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG--PPGPPGPPGPGIDMSAFAGLGPREK 1231

Query: 253  GPPPPGKPQGPPAQGG----------------SKSQSARSPPGKPQGP 284
            GP P    +   A GG                ++ +S RSP G  + P
Sbjct: 1232 GPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNP 1279



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 51/163 (31%), Positives = 59/163 (36%), Gaps = 59/163 (36%)

Query: 217 GKPQGPPPQGGNQ--------PQGPPPP--PGKPQGPPPQGGNKPQ-GPPPPGKPQGPPA 265
           G+P GP  Q G          P+GPP P  P   QGP    G+K + G P P    G P 
Sbjct: 98  GQP-GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 156

Query: 266 QGGSKSQSARSPPGKPQGPPQQEG-------------------------------NNPQG 294
             G+       PPG P GPP   G                                 P+G
Sbjct: 157 TPGNPG-----PPG-PPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG 210

Query: 295 PPPPAG--------GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           PP PAG        GNP +P  P    P GP  PP  G P +P
Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPP--GPPGKP 251



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 29/98 (29%), Positives = 33/98 (33%), Gaps = 26/98 (26%)

Query: 245 PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK------PQGPPQQEG--------- 289
           P G   P  P       G P   G K +     PG       P+GPP  +G         
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGE-----PGDIKDIVGPKGPPGPQGPAGEQGPRG 135

Query: 290 ----NNPQGPPPPAG--GNPQQPQAPPAGQPQGPPRPP 321
                  +G P P G  G P  P  P    P GPP PP
Sbjct: 136 DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPP 173


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  136 bits (343), Expect = 2e-32
 Identities = 124/353 (35%), Positives = 142/353 (40%), Gaps = 76/353 (21%)

Query: 33   AGNPQGPS----PQGGNKPQGPPPPPGKPQ-----GPPPQGGNK-PQGPPPPGKPQGPP- 81
            A  PQGP+    P+G    QGPP   G P      GPP   GN  P GPP P    GP  
Sbjct: 802  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 861

Query: 82   PQGDKS----------RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGG 126
             +GD            + P  PPG+   P   G +  +GPP P G        G P Q G
Sbjct: 862  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG 921

Query: 127  NR--PQGPPP---PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP-- 179
             R  P  P P   PGK   P   GD     R PPG P GPP   G  P G P   G P  
Sbjct: 922  ERGFPGLPGPSGEPGKQGAPGASGD-----RGPPG-PVGPPGLTG--PAGEPGREGSPGA 973

Query: 180  QGPPPQGGKK--------------PQGPPPPGKPQGPPP---QGDKSRSSQSPPGKPQGP 222
             GPP + G                P  P PPG P    P   QGD+  +    P  P GP
Sbjct: 974  DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1033

Query: 223  PPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQG-------PPPPGKPQGPPAQGGSKSQSA 274
                G Q PQGP    G+   P  +G    +G       P PPG      A G +     
Sbjct: 1034 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1093

Query: 275  RSPPGKPQGPPQQEGNN----PQGPPPPAGGNPQQPQAPPAGQPQ--GPPRPP 321
            R PPG P GP  ++G N    P GPP P G   +  +  PAG P   GPP PP
Sbjct: 1094 RGPPG-PVGPSGKDGANGIPGPIGPPGPRG---RSGETGPAGPPGNPGPPGPP 1142



 Score =  127 bits (319), Expect = 1e-29
 Identities = 136/407 (33%), Positives = 156/407 (38%), Gaps = 121/407 (29%)

Query: 33  AGNPQGPS-PQGGNKPQGPPPPPG-----KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
           A  P GP+ P G    QG P P G      P GPP +GG KP     PG+   P   G  
Sbjct: 571 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGG-KPGDQGVPGEAGAPGLVGP- 628

Query: 87  SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP----PPGKPQGPP 142
            R  R  PG+   P  QG    QGP   PG P    P+G + P GPP    PPG  QG P
Sbjct: 629 -RGERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMP 683

Query: 143 ----------PQGDKS----RSPRSPPGK--------PQGPP-PQGGNQPQGPPPPPGK- 178
                     P+GD+     + P   PGK        P GPP P G N  +G   PPG  
Sbjct: 684 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 743

Query: 179 ----------------PQGP-----PP-------------QGGKK-------PQGPPPPG 197
                           P GP     PP             + G+K       PQGP    
Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803

Query: 198 KPQGPP----PQGDKSRSSQSPPGKPQGPP------PQGGNQPQGPPPPPGKPQGPPPQG 247
            PQGP     P+G  +R +Q PPG    P       P G N   GPP PPG      P+G
Sbjct: 804 GPQGPTGVTGPKG--ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 861

Query: 248 GNKPQGPP----PPGK--PQGPPAQGGSKS----QSARSPPGKPQGPPQQEG-------N 290
                GPP     PG   P GPP + G         A  PPG PQG   Q G        
Sbjct: 862 ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG-PQGLAGQRGIVGLPGQR 920

Query: 291 NPQGPP--PPAGGNPQQPQAPPAGQPQGPPRP--PQG-----GRPSR 328
             +G P  P   G P +  AP A   +GPP P  P G     G P R
Sbjct: 921 GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 967



 Score =  122 bits (305), Expect = 6e-28
 Identities = 131/408 (32%), Positives = 153/408 (37%), Gaps = 97/408 (23%)

Query: 13  LSSAQNLNEDVSQEESPSL-----IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNK 67
           L+  +  N D  +   P L     + G P    PQG   P G P   G+P  P PQG   
Sbjct: 469 LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528

Query: 68  PQGP---PPPGKPQGPPPQGDKSRSPRSP-----PGKP-----QGPP----PQGGNQPQG 110
             G    P P    G P +  +   P +P     PGK       GPP    P G    QG
Sbjct: 529 QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 588

Query: 111 PPPPPG-----KPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
            P P G      P GPP +GG +P     PG+   P   G   R  R  PG+   P  QG
Sbjct: 589 APGPSGFQGLPGPPGPPGEGG-KPGDQGVPGEAGAPGLVGP--RGERGFPGERGSPGAQG 645

Query: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPP----PPGKPQGPP----------PQGDKS-- 209
               QGP   PG P    P+G   P GPP    PPG  QG P          P+GD+   
Sbjct: 646 ---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDV 701

Query: 210 --RSSQSPPGK--------PQGPP-PQGGNQPQG---PPPPPGKPQGPPPQGGNKPQGPP 255
             +  +  PGK        P GPP P G N  +G   PP P G        G     GPP
Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761

Query: 256 PPGKPQGPPA---QGGSKSQ----------SARSPPGK-----PQGPPQQEG----NNPQ 293
            P    GPP    Q G+K +           A  P G      PQGP    G       Q
Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821

Query: 294 GPP-----PPAGGNPQQPQAPPAGQPQGPPRP-----PQGGR-PSRPP 330
           GPP     P A G    P +     P GPP P     P+G R  S PP
Sbjct: 822 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869



 Score =  120 bits (302), Expect = 1e-27
 Identities = 111/356 (31%), Positives = 136/356 (38%), Gaps = 71/356 (19%)

Query: 36  PQGP-SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGDKSRSPRSP 93
           P+GP  P G   PQG    PG+P  P   G   P+GPP PPGKP      GD   + +  
Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP------GDDGEAGKPG 192

Query: 94  PGKPQGPP-PQGGNQPQGPPPPPGKP--QGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150
               +GPP PQG     G P  PG    +G P   G + +   P  K +   P  + S  
Sbjct: 193 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG 252

Query: 151 PRSPPGKP-----QGPPPQGGNQ-------PQGPPPPPGKPQGPP------------PQG 186
           P  P G P      GP    G +       P GPP P G   GP             P G
Sbjct: 253 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 312

Query: 187 GKKPQGPP----PPGKPQGPPPQGDK----------SRSSQSPPG--------KPQGPP- 223
            + P+G       PG P  P P G            ++ S   PG         P+GPP 
Sbjct: 313 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 372

Query: 224 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ-SARSPPGK-- 280
           PQG   P GP    G+P     +G   P+G P P  PQG P   G + +  AR  PG   
Sbjct: 373 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432

Query: 281 PQGPPQQEG----------NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326
           P GPP + G          +   GP    G       A P G    P RP + G P
Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 488



 Score =  120 bits (301), Expect = 2e-27
 Identities = 97/305 (31%), Positives = 117/305 (38%), Gaps = 41/305 (13%)

Query: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---- 79
            S ++ P    G+   P   G    QGP  PPG+   P   G +  +GPP P    G    
Sbjct: 854  SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI 913

Query: 80   ---PPPQGDKS----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNRPQ 130
               P  +G++       P   PGK   P   G   P GP  PPG   P G P + G+ P 
Sbjct: 914  VGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS-PG 972

Query: 131  GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190
               PPG+      +GD+  +     G P  P P G   P GP    G       QG   P
Sbjct: 973  ADGPPGRDGAAGVKGDRGET--GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030

Query: 191  QGPPPPGKPQGPP-PQGDKSRSS----------------QSPPGKPQGPPPQGGNQPQGP 233
             GP      QGP  P+GDK  +                 Q  PG P     QG + P GP
Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090

Query: 234  PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293
              P G P    P G +   G P P  P GP  +G S       PPG P GPP      P 
Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPGPIGPPGP--RGRSGETGPAGPPGNP-GPP-----GPP 1142

Query: 294  GPPPP 298
            GPP P
Sbjct: 1143 GPPGP 1147



 Score =  118 bits (295), Expect = 8e-27
 Identities = 114/336 (33%), Positives = 130/336 (38%), Gaps = 65/336 (19%)

Query: 34  GNPQGPSPQG--------GNKPQGPPPPPGKPQGPPPQGGN----------KPQGPPPPG 75
           G    P P+G        GN   GPP PPG P GPP  GGN          +  G    G
Sbjct: 72  GEKGAPGPRGRDGEPGTPGNP--GPPGPPGPP-GPPGLGGNFAAQMAGGFDEKAGGAQLG 128

Query: 76  KPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP- 133
             QGP  P G     PR PPG    P PQG    QG P  PG+P    P G   P+GPP 
Sbjct: 129 VMQGPMGPMG-----PRGPPGPAGAPGPQGF---QGNPGEPGEPGVSGPMG---PRGPPG 177

Query: 134 PPGKPQGPPPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKP--QGPPPQGGKKP 190
           PPGKP      GD   + +      +GPP PQG     G P  PG    +G P   G K 
Sbjct: 178 PPGKP------GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 231

Query: 191 QGPPP--------PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ----PQGPPPPPG 238
           +   P        PG+   P P G +    +     P G     GN     P GPP P G
Sbjct: 232 EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291

Query: 239 KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP-PQQEGNNP--QGP 295
              GP   G    +G   P   +GP       +Q  R  PG P  P P     NP   G 
Sbjct: 292 PAGGPGFPGAPGAKGEAGPTGARGPEG-----AQGPRGEPGTPGSPGPAGASGNPGTDGI 346

Query: 296 PPPAG--GNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           P   G  G P    AP    P+GPP P     P  P
Sbjct: 347 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 382



 Score =  114 bits (286), Expect = 9e-26
 Identities = 109/334 (32%), Positives = 131/334 (39%), Gaps = 57/334 (17%)

Query: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG----PP 81
           EE      G P G  P G   P G    PG    P   G   P+G P    P G      
Sbjct: 418 EEGKRGARGEPGGVGPIG---PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 474

Query: 82  PQGDKSR-------SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP-- 132
             GD  R         R   G+P    PQG   P G P   G+P  P PQG     G   
Sbjct: 475 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 534

Query: 133 -PPPGKPQGPPPQGDKSRSPRSP-----PGK-----PQGPP----PQGGNQPQGPPPPPG 177
            P P    G P +  +   P +P     PGK       GPP    P G    QG P P G
Sbjct: 535 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594

Query: 178 -----KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG 232
                 P GPP +GG KP     PG+   P   G   R  +  PG+   P  QG    QG
Sbjct: 595 FQGLPGPPGPPGEGG-KPGDQGVPGEAGAPGLVG--PRGERGFPGERGSPGAQG---LQG 648

Query: 233 PPPPPGKPQGPPPQGGNKPQGPP----PPGKPQGPPAQGGSKS----QSARSPPGK--PQ 282
           P   PG P    P+G + P GPP    PPG  QG P + G+      +  R   G+  P+
Sbjct: 649 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDVGEKGPE 707

Query: 283 GPPQQEG----NNPQGPPPPAGGNPQQPQAPPAG 312
           G P ++G      P GPP PAG N ++ +  P G
Sbjct: 708 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741



 Score =  111 bits (278), Expect = 8e-25
 Identities = 115/379 (30%), Positives = 139/379 (36%), Gaps = 100/379 (26%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP---------QGPP-PPGKPQGPPPQ 83
           GN   P P G   P GP   PG P  P  +G   P         QGP   PG P  P P 
Sbjct: 276 GNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA 335

Query: 84  GDK----------SRSPRSPPG--------KPQGPP-PQGGNQPQGPPPPPGKPQGPPPQ 124
           G            ++     PG         P+GPP PQG   P GP    G+P     +
Sbjct: 336 GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 395

Query: 125 GGNRPQGPPPPGKPQGPP-PQGDKSR----------SPRSPPGK---------------- 157
           G   P+G P P  PQG P P G++ +           P  PPG+                
Sbjct: 396 GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 455

Query: 158 -PQGPP----------PQGGNQPQGPPPPPGKP-----QGPP----PQGGKKPQGPP-PP 196
            P+G P          P+G N   G P  PG P      G P    PQG   P G P   
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515

Query: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN-QP-----QGPPPPPGKPQGPPPQGGNK 250
           G+P  P PQG + +     PG    P P+G N +P     +G P  PG    P   G   
Sbjct: 516 GRPGPPGPQGARGQ-----PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 570

Query: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAG--------- 300
             GPP P  P G   + G+   S       P GPP + G    QG P  AG         
Sbjct: 571 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 630

Query: 301 --GNPQQPQAPPAGQPQGP 317
             G P +  +P A   QGP
Sbjct: 631 ERGFPGERGSPGAQGLQGP 649



 Score =  111 bits (278), Expect = 8e-25
 Identities = 112/349 (32%), Positives = 134/349 (38%), Gaps = 64/349 (18%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG----PPPQG 84
           P+  +GNP      G     G P   G P  P P+G   PQG   P  P+G    P   G
Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG 393

Query: 85  DK-SRSPRSPPGK--PQGPP-------------PQGGNQPQGPPPPPGKP--QGPPPQGG 126
            K  + P+  PG   PQG P               GG  P GPP   G P  +G P Q G
Sbjct: 394 FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDG 453

Query: 127 -NRPQGPPPPGKPQG----PPPQGDKSR-------SPRSPPGKPQGPPPQGGNQPQGPPP 174
              P+G P    P G        GD  R         R   G+P    PQG   P G P 
Sbjct: 454 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 513

Query: 175 PPGKPQGPPPQGGKKPQG----PPPPGKPQGPPPQGDKSRSSQSPPGKP--QGPPPQGGN 228
             G+P  P PQG +   G    P P G    P   G+K       PG P  +G P + G 
Sbjct: 514 EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL-----PGAPGLRGLPGKDGE 568

Query: 229 QPQGPPPPPGKPQG-------PPPQGGNKPQGPPPP----GKP--QGPPAQGGSKS---- 271
                PP P  P G       P P G     GPP P    GKP  QG P + G+      
Sbjct: 569 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 628

Query: 272 QSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP--QGPP 318
           +  R  PG+   P  Q    P+G P   G +  +  + PAG P  QGPP
Sbjct: 629 RGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 677



 Score =  111 bits (277), Expect = 1e-24
 Identities = 102/330 (30%), Positives = 129/330 (39%), Gaps = 42/330 (12%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGK-----PQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
           + G    P   G   P GP   PG+     P G     GN   G P P  P GP      
Sbjct: 238 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN--DGQPGPAGPPGPVGPAGG 295

Query: 87  SRSPRSPPGKPQGPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
              P +P  K +  P     P+G   P+G P  PG P GP    GN      P  K    
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSP-GPAGASGNPGTDGIPGAKGSAG 354

Query: 142 PPQGDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
            P    + +P  P   P+GPP PQG   P GP    G+P     +G + P+G P P  PQ
Sbjct: 355 AP--GIAGAPGFPG--PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 410

Query: 201 GPP-PQGDKSRSSQ----------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
           G P P G++ +              PPG+   P  +G     G   P G P    P G  
Sbjct: 411 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 470

Query: 250 KPQG----PPPPGKPQGPPAQGGSKSQSARSPPGK--PQGPPQQEGNNPQGPPPPAGGNP 303
            P+G    P  PG+P  P A+G +       P GK  P G P ++G    GPP P G   
Sbjct: 471 GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR--PGPPGPQG-AR 527

Query: 304 QQPQAPPAGQPQG----PPRPPQGGRPSRP 329
            QP       P+G    P +  + G P  P
Sbjct: 528 GQPGVMGFPGPKGANGEPGKAGEKGLPGAP 557



 Score =  100 bits (250), Expect = 1e-21
 Identities = 92/288 (31%), Positives = 110/288 (38%), Gaps = 40/288 (13%)

Query: 29   PSLIAGNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
            PS   G    P   G   P GP  PPG   P G P + G+ P    PPG+      +GD+
Sbjct: 931  PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS-PGADGPPGRDGAAGVKGDR 989

Query: 87   SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-PQG 145
              +     G P  P P G   P GP    G       QG   P GP      QGP  P+G
Sbjct: 990  GET--GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047

Query: 146  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP----PQGGKKPQGPPPPGKPQG 201
            DK  +    PG+      +G    QG P PPG P G      P G   P+GPP P  P G
Sbjct: 1048 DKGEA--GEPGERGLKGHRGFTGLQGLPGPPG-PSGDQGASGPAGPSGPRGPPGPVGPSG 1104

Query: 202  -------PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP--Q 252
                   P P G      +S    P GPP   G  P GPP PPG         G  P  +
Sbjct: 1105 KDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG--PPGPPGPPGPGIDMSAFAGLGPREK 1162

Query: 253  GPPPPGKPQGPPAQGG----------------SKSQSARSPPGKPQGP 284
            GP P    +   A GG                ++ +S RSP G  + P
Sbjct: 1163 GPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNP 1210



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 45/142 (31%), Positives = 52/142 (36%), Gaps = 50/142 (35%)

Query: 230 PQGPPPP--PGKPQGPPPQGGNKPQ-GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
           P+GPP P  P   QGP    G+K + G P P    G P   G+       PPG P GPP 
Sbjct: 49  PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPG-----PPG-PPGPPG 102

Query: 287 QEG-------------------------------NNPQGPPPPAG--------GNPQQPQ 307
             G                                 P+GPP PAG        GNP +P 
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 308 APPAGQPQGPPRPPQGGRPSRP 329
            P    P GP  PP  G P +P
Sbjct: 163 EPGVSGPMGPRGPP--GPPGKP 182



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 23/77 (29%)

Query: 266 QGGSKSQSARSPPGK------PQGPPQQEG-------------NNPQGPPPPAG--GNPQ 304
           Q G K Q  +  PG       P+GPP  +G                +G P P G  G P 
Sbjct: 30  QPGPKGQ--KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 87

Query: 305 QPQAPPAGQPQGPPRPP 321
            P  P    P GPP PP
Sbjct: 88  TPGNPGPPGPPGPPGPP 104


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score =  136 bits (342), Expect = 3e-32
 Identities = 121/364 (33%), Positives = 143/364 (39%), Gaps = 87/364 (23%)

Query: 39  PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR-------SPR 91
           P PQG    +G    PG  +GP  Q G   +GP  P    GPP  G+K          P 
Sbjct: 599 PGPQGPKGQKGSVGDPGM-EGPMGQRGR--EGPMGPRGEAGPPGSGEKGERGAAGEPGPH 655

Query: 92  SPPGKPQGPPPQGGNQPQGPPPPPGKPQG----------PPPQGGNRPQGPPPPGKPQG- 140
            PPG P    P+G +   GP  PPG P G          P  +G   P GPP P   QG 
Sbjct: 656 GPPGVPGSVGPKGSSGSPGPQGPPG-PVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE 714

Query: 141 ---------------PPPQGDKSRSPRSPPGKPQGPPPQGGNQP-------QGPPPPPGK 178
                          P   G+        P  P G     G Q        +GPP P G 
Sbjct: 715 KGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD 774

Query: 179 PQGPPPQGGKKPQG-PPPPGKP--QGPPPQGDKSRSSQ-----------------SPPGK 218
           P  P   G + PQG P  PG+P  +G P    K  +S+                  PPG 
Sbjct: 775 PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP 834

Query: 219 PQGPPPQG-----GNQP----QGPPPPPGK--PQGPPPQGGNKPQGPPPPG--KPQGPPA 265
           P  P P G     G+Q     QGPP PPG   P GP   G   P+GPP  G   P GPP 
Sbjct: 835 PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPG 894

Query: 266 QGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ--PQAPPAGQP------QGP 317
              S S++  S P  P GPP  +G+  QGPP P G   +Q  P    +G        QGP
Sbjct: 895 SFLSNSETFLSGPPGPPGPPGPKGD--QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGP 952

Query: 318 PRPP 321
           P PP
Sbjct: 953 PGPP 956



 Score =  135 bits (341), Expect = 4e-32
 Identities = 118/351 (33%), Positives = 137/351 (39%), Gaps = 68/351 (19%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPP---PQGGNKPQGPPPPGKPQGPPPQGDKSR-- 88
           G P  P P G   PQGP    G    P    P G    +GP  P    GPP  G+K    
Sbjct: 588 GTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERG 647

Query: 89  -----SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG----------PPPQGGNRPQGPP 133
                 P  PPG P    P+G +   GP  PPG P G          P  +G   P GPP
Sbjct: 648 AAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPG-PVGLQGLRGEVGLPGVKGDKGPMGPP 706

Query: 134 PPGKPQG----------------PPPQGDKSRSPRSPPGKPQGPPPQGGNQP-------Q 170
            P   QG                P   G+        P  P G     G Q        +
Sbjct: 707 GPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIR 766

Query: 171 GPPPPPGKPQGPPPQGGKKPQG-PPPPGKP--QGPPPQGDKSRSSQSP-----PGKPQGP 222
           GPP P G P  P   G + PQG P  PG+P  +G P    K  +S+       PG P GP
Sbjct: 767 GPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPP-GP 825

Query: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKP----QGPPPPGKPQGPPAQGGSKSQSARSPP 278
           P  G   P GPP  PG P GP    G++     QGPP P  P+GPP        S   PP
Sbjct: 826 P--GAMGPPGPPGAPG-PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP------SIPGPP 876

Query: 279 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
           G P+GPP +    P GPP     N +   + P G P GPP P     P  P
Sbjct: 877 G-PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPG-PPGPPGPKGDQGPPGP 925



 Score =  128 bits (322), Expect = 6e-30
 Identities = 112/311 (36%), Positives = 127/311 (40%), Gaps = 64/311 (20%)

Query: 37   QGPSPQGG--NKP--QGPPPPPGKPQGPPPQGGNKPQG-PPPPGKP--QGPPPQGDK--- 86
            QGP  + G    P  +GPP P G P  P   G   PQG P  PG+P  +G P    K   
Sbjct: 751  QGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810

Query: 87   --SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP----QGPPPPGKPQG 140
                S  + PG P GPP  G   P GPP  PG P GP    G++     QGPP P  P+G
Sbjct: 811  SEGSSMLTVPGPP-GPP--GAMGPPGPPGAPG-PAGPAGLPGHQEVLNLQGPPGPPGPRG 866

Query: 141  PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP------------PPGKPQGPPPQGGK 188
            PP       S   PPG P+GPP +G   P GPP             PPG P  P P+G +
Sbjct: 867  PP-----GPSIPGPPG-PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQ 920

Query: 189  KPQGPPPPGKPQGPPPQGDKSRSS-----QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 243
             P GP      QG P       SS     Q PPG P    P+G     G P   G P GP
Sbjct: 921  GPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGP 980

Query: 244  PPQGGNKPQGPPPPGKPQGPPAQGGS----------------KSQSARSPPGKPQGPPQQ 287
               G +       P  P GPP   GS                +S S RS     QGPP  
Sbjct: 981  SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPP-- 1038

Query: 288  EGNNPQGPPPP 298
                P GPP P
Sbjct: 1039 ---GPPGPPGP 1046



 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 82/248 (33%), Positives = 100/248 (40%), Gaps = 54/248 (21%)

Query: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSP--PGKPQGPPPQGGNQPQGPPPPPGKPQG 181
           + GN    P P G    P P+GD+   P +P  PG    P PQG   P+G     G P  
Sbjct: 561 ENGNLRGSPGPKGDMGSPGPKGDRG-FPGTPGIPGPLGHPGPQG---PKGQKGSVGDPGM 616

Query: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDK-SRSSQSPPGKPQGPP-------PQGGNQPQGP 233
             P G +  +GP  P    GPP  G+K  R +   PG P GPP       P+G +   GP
Sbjct: 617 EGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG-PHGPPGVPGSVGPKGSSGSPGP 675

Query: 234 PPPPGKPQG----------PPPQGGNKPQGPPPPGKPQG----------------PPAQG 267
             PPG P G          P  +G   P GPP P   QG                P A G
Sbjct: 676 QGPPG-PVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG 734

Query: 268 GSKSQSARSPPGKP--QGPPQQEG----NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
              ++ A  P G    QGP  ++G       +GPP P+G     P  P    PQGP   P
Sbjct: 735 EPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSG----DPGKPGLTGPQGPQGLP 790

Query: 322 QGGRPSRP 329
             G P RP
Sbjct: 791 --GTPGRP 796



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 93/360 (25%), Positives = 114/360 (31%), Gaps = 102/360 (28%)

Query: 9    ALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQG--------------GNKPQGPPPPP 54
            +LL+L  A+  +  +S   S  +  G P  P P G              G++ +G   PP
Sbjct: 1121 SLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPP 1180

Query: 55   GKPQGPPPQGGNK-----------------------PQGPPPPGKPQGPPP--------Q 83
            G P GPP   GN                        P GPP P  P+GPP          
Sbjct: 1181 GPP-GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYA 1239

Query: 84   GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG------GNRPQGPPPPGK 137
             + S S RS         P   +   GPP PPG PQGPP          +  +G      
Sbjct: 1240 AENSDSFRSELISYL-TSPDVRSFIVGPPGPPG-PQGPPGDSRLLSTDASHSRGSSSSSH 1297

Query: 138  PQGPPPQGDKSRSPRSPPGKPQGPPPQGG--NQPQGPPPPPGKPQGPPPQGGKKPQGPPP 195
                  +G    S  S  G   G    GG   +  G   P G   GP    G   +G   
Sbjct: 1298 SSSVR-RGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMY 1356

Query: 196  PGKPQ--GPPPQGDKSRSS----------------------QSPPGKP--QGPPP----- 224
             G     G    GD   +                       Q PPG+P  QGPP      
Sbjct: 1357 AGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF 1416

Query: 225  --------------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
                          Q     QGPP   G+   P P+G   P GPP    P GP    G K
Sbjct: 1417 SAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEK 1476



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 96/373 (25%), Positives = 104/373 (27%), Gaps = 170/373 (45%)

Query: 108  PQGPPPPPGKPQGPP-----------------PQGGNRPQGPPPPGKPQGPPP------- 143
            P+GPP PPG                          G     P PPG P  P         
Sbjct: 1107 PRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLS 1166

Query: 144  --QGDKSRSPRSPPGKPQGPPPQGGNQ-----------------------PQGPPPPPGK 178
              +G + R    PPG P GPP   GN                        P GPP PPG 
Sbjct: 1167 LLRGSEFRGIVGPPGPP-GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPG- 1224

Query: 179  PQGPPPQGGKKPQ---------------------------GPPPPGKPQGPPP------- 204
            P+GPP   G                               GPP P  PQGPP        
Sbjct: 1225 PRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLST 1284

Query: 205  ------------------QGDKSRSSQSPPGKPQGPPPQGG--------NQPQGPPPPPG 238
                              +G    SS S  G   G    GG          P G    PG
Sbjct: 1285 DASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG 1344

Query: 239  KPQGPPPQGGNKP----------------------------------------QGPPPPG 258
               G   +GG                                           QGPP   
Sbjct: 1345 GGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQP 1404

Query: 259  KPQGPPAQGGSKSQSARSPP-----------GKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 307
             PQGPP  G SK  SA S             G  QGPP Q+G    G P P G   + P 
Sbjct: 1405 GPQGPP--GISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE--MGTPGPKG--DRGPA 1458

Query: 308  APPAGQPQGPPRP 320
             PP G P GPP P
Sbjct: 1459 GPP-GHP-GPPGP 1469



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 34/94 (36%)

Query: 98   QGPPPQGGNQPQGPP--------------------PPPGKPQGPPPQGGNRPQGPPPPGK 137
            QGPP Q G  PQGPP                       G  QGPP Q           G+
Sbjct: 1398 QGPPGQPG--PQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQ----------KGE 1445

Query: 138  PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 171
               P P+GD  R P  PPG P  P P+G    +G
Sbjct: 1446 MGTPGPKGD--RGPAGPPGHPGPPGPRGHKGEKG 1477



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 34/115 (29%)

Query: 16   AQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPP--------------------PPPG 55
            A  ++E + ++     +A   QGP  Q G  PQGPP                       G
Sbjct: 1377 AVRVSESMQRQGLLQGMAYTVQGPPGQPG--PQGPPGISKVFSAYSNVTADLMDFFQTYG 1434

Query: 56   KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 110
              QGPP Q           G+   P P+GD  R P  PPG P  P P+G    +G
Sbjct: 1435 AIQGPPGQ----------KGEMGTPGPKGD--RGPAGPPGHPGPPGPRGHKGEKG 1477


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score =  135 bits (339), Expect = 7e-32
 Identities = 96/250 (38%), Positives = 105/250 (42%), Gaps = 41/250 (16%)

Query: 55  GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 111
           G+ +  PP G ++   PQG    G+  G  P GD+   P  P G P  PP   G   Q P
Sbjct: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAG---QTP 236

Query: 112 PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP-----GKPQGPPPQGG 166
           P PP  P GPP      P GPPPPG+   PP  G  +R  R PP     G+P G PP G 
Sbjct: 237 PRPPLGPPGPPG-----PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291

Query: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226
             P  PPP PG   GPPP      QGPPPP  P  P P G            P GPP   
Sbjct: 292 LPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPG------------PLGPPLTL 337

Query: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
              P  P PPPG P  PP    N    PPP          G   S S   PP  P G P 
Sbjct: 338 APPPHLPGPPPGAP--PPAPHVNPAFFPPPTN-------SGMPTSDSRGPPPTDPYGRPP 388

Query: 287 QEGNNPQGPP 296
                  GPP
Sbjct: 389 PYDRGDYGPP 398



 Score =  127 bits (319), Expect = 1e-29
 Identities = 91/229 (39%), Positives = 99/229 (43%), Gaps = 50/229 (21%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPPP-------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
           P  + G  + P P G   P GPPPP       P  P GPP   G  P GPPPPG+   PP
Sbjct: 208 PGAVPGGDRFPGPAG---PGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPP 262

Query: 82  PQGDKSRSPRSPP-----GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136
             G  +R  R PP     G+P G PP G   P  PPP PG   GPPP       GPPPP 
Sbjct: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPP-------GPPPP- 312

Query: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
             QGPPP       P  PPG P GPP      P  P PPPG    PPP     P   PPP
Sbjct: 313 -QQGPPP--PPGPFPPRPPG-PLGPPLTLAPPPHLPGPPPG---APPPAPHVNPAFFPPP 365

Query: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245
                         +S  P    +GPPP     P G PPP  +    PP
Sbjct: 366 -------------TNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPP 398



 Score =  126 bits (316), Expect = 3e-29
 Identities = 94/247 (38%), Positives = 107/247 (43%), Gaps = 28/247 (11%)

Query: 83  QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-QGGNRPQGPPPPGKPQGP 141
           Q  K+       G+ +  PP G ++   P    G+ + P    GG+R  GP  PG   GP
Sbjct: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG---GP 226

Query: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP---PGK 198
           PP     ++P  PP  P GPP   G  P G   PP  P   PP  G +P  PPP   PG+
Sbjct: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPP--PLAGPPNRGDRP--PPPVLFPGQ 282

Query: 199 PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258
           P G PP G        PPG P  PP  G   P GPPPP    QGPPP  G  P  P PPG
Sbjct: 283 PFGQPPLGPL------PPGPP--PPVPGYGPPPGPPPPQ---QGPPPPPGPFP--PRPPG 329

Query: 259 KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP-QQPQAPPAGQPQGP 317
            P GPP            PPG P  PP    N    PPP   G P    + PP   P G 
Sbjct: 330 -PLGPPLTLAPPPHLPGPPPGAP--PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386

Query: 318 PRPPQGG 324
           P P   G
Sbjct: 387 PPPYDRG 393



 Score = 91.7 bits (226), Expect = 8e-19
 Identities = 72/206 (34%), Positives = 86/206 (41%), Gaps = 40/206 (19%)

Query: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-QGGKKPQGPPPPGKPQGP 202
           Q  K+       G+ +  PP G ++   P    G+ + P    GG +  GP  PG P  P
Sbjct: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP 229

Query: 203 PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPP--PPPGK----PQGPPPQGGNKPQGPPP 256
            P G      Q+PP  P GPP      P GPP  PPPG+    P   PP  G++P  PPP
Sbjct: 230 FPAG------QTPPRPPLGPPG-----PPGPPGPPPPGQVLPPPLAGPPNRGDRP--PPP 276

Query: 257 ---PGKPQGPPAQGGSKSQSARSPPGKP-----QGPPQQEGNNPQGPPPPAGGNPQQPQA 308
              PG+P G P  G         PPG P      GPP       QGPPPP G  P +P  
Sbjct: 277 VLFPGQPFGQPPLG-------PLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329

Query: 309 P-----PAGQPQGPPRPPQGGRPSRP 329
           P         P   P PP G  P  P
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGAPPPAP 355



 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 66/165 (40%), Positives = 73/165 (44%), Gaps = 29/165 (17%)

Query: 177 GKPQGPPPQGGKK---PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233
           G+ +  PP G  +   PQG    G+  G  P GD+      P G P  PP   G   Q P
Sbjct: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAG---QTP 236

Query: 234 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPP----GKPQGPPQQEG 289
           P PP  P GPP      P GPPPPG+   PP  G         PP    G+P G P    
Sbjct: 237 PRPPLGPPGPPG-----PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQP---- 287

Query: 290 NNPQGPPPPAGGNPQQP-QAPPAGQP---QGPPRPPQGGRPSRPP 330
             P GP PP G  P  P   PP G P   QGPP PP G  P RPP
Sbjct: 288 --PLGPLPP-GPPPPVPGYGPPPGPPPPQQGPP-PPPGPFPPRPP 328



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 54/144 (37%), Positives = 56/144 (38%), Gaps = 34/144 (23%)

Query: 29  PSLIAGNPQGPSPQGGNKPQGPPP------PPGKP----QGPPPQGGNKPQGPPPPGKPQ 78
           P L  G P G  P G   P  PPP      PPG P      PPP G   P  P PPG P 
Sbjct: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPG---PFPPRPPG-PL 331

Query: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNRPQGP---P 133
           GPP          +PP    GPP      P  PPP P       PPP     P      P
Sbjct: 332 GPP-------LTLAPPPHLPGPP------PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378

Query: 134 PPGKPQGPPPQGDKSRSPRSPPGK 157
           PP  P G PP  D  R    PPG+
Sbjct: 379 PPTDPYGRPPPYD--RGDYGPPGR 400


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  135 bits (339), Expect = 7e-32
 Identities = 117/344 (34%), Positives = 134/344 (38%), Gaps = 70/344 (20%)

Query: 38  GPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK------PQGPPPQGDKS---- 87
           G + Q G    G P  PG+   P PQG   P GPP  GK      P  P  +GD+     
Sbjct: 183 GMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGE 242

Query: 88  RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDK 147
             P  PPG PQGPP + G +  G P   G P  P   G     G P    P GPP  G  
Sbjct: 243 MGPIGPPG-PQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKP 301

Query: 148 S----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP-PGKPQGP 202
                +  R P G P GP  +G    QGP   PGKP    P G   PQGP   PG    P
Sbjct: 302 GLPGLKGERGPAGLPGGPGAKG---EQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLP 358

Query: 203 PPQGDKS-------------RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249
            P+G+               R S    GKP  P   G + P+G P  PG P+G P  GG 
Sbjct: 359 GPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPG-PKGDPGVGG- 416

Query: 250 KPQGPPPPGKPQGPPAQGGSKSQSAR-------------SPPGKP-----------QGPP 285
            P G P P  P G     G   ++                PPG P            GPP
Sbjct: 417 -PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPP 475

Query: 286 QQEG------NNPQGPPPPAG--GNPQQPQAPPAGQPQGPPRPP 321
              G      N P GPP P G  G+  +P  P    P GPP PP
Sbjct: 476 GPAGIATKGLNGPTGPPGPPGPRGHSGEPGLP---GPPGPPGPP 516



 Score =  132 bits (333), Expect = 3e-31
 Identities = 133/403 (33%), Positives = 150/403 (37%), Gaps = 111/403 (27%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKP-------------QGPP-PQGGNKPQGPPPPGKP-- 77
           G P  P P G     GP  PPGKP              GPP P    KP  P  PGKP  
Sbjct: 60  GTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGE 119

Query: 78  QGP-PPQGDKSRS----PRSPPGKPQGPPPQGGNQP-----QGPPPPPGKPQG------- 120
           +GP  P+GD   +    PR PPG P  P P G + P     QGP   PG P+G       
Sbjct: 120 RGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG-PRGFPGEKGA 178

Query: 121 --------------------------PPPQGGNRPQGPPPPGK------PQGPPPQGDKS 148
                                     P PQG   P GPP  GK      P  P  +GD+ 
Sbjct: 179 PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRG 238

Query: 149 ----RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK---------PQGPPP 195
                 P  PPG PQGPP + G +  G P   G P  P   G K          P GPP 
Sbjct: 239 FPGEMGPIGPPG-PQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG 297

Query: 196 PGKP--------QGPP--PQGDKSRSSQSP---PGKPQGPPPQGGNQPQGPPPPPGKPQG 242
            GKP        +GP   P G  ++  Q P   PGKP    P G   PQGP   PG    
Sbjct: 298 FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL 357

Query: 243 PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP--------QGPPQQEGNNPQG 294
           P P+G   P GP   G P     +G   S      PGKP         G P  +G+   G
Sbjct: 358 PGPKGETGPAGPA--GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVG 415

Query: 295 PPP-------PAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
            PP       PAG          AG P+G P  P    P  PP
Sbjct: 416 GPPGLPGPVGPAGAKGMPGHNGEAG-PRGAPGIPGTRGPIGPP 457



 Score =  131 bits (330), Expect = 7e-31
 Identities = 115/328 (35%), Positives = 130/328 (39%), Gaps = 43/328 (13%)

Query: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
           + G    P P G   P+G P P G P G P  G    QG P    P GP   G     P 
Sbjct: 55  VRGEQGTPGPPGPAGPRGHPGPSG-PPGKPGYGSPGLQGEPGLPGPPGPSAVG----KPG 109

Query: 92  SP--PGKPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNRPQGPPPPGKPQGPPPQGDKS 148
            P  PGKP    P G     GP   PG P+GPP P G   P G   PGKP    P G  +
Sbjct: 110 VPGLPGKPGERGPYGPKGDVGPAGLPG-PRGPPGPPGIPGPAGISVPGKPGQQGPTG--A 166

Query: 149 RSPRSPPGKPQGPPPQG-----GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGK----- 198
             PR  PG+   P   G     G    G P  PG+   P PQG   P GPP  GK     
Sbjct: 167 PGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENG 226

Query: 199 -PQGPPPQGDKSRSSQ----SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 253
            P  P  +GD+    +     PPG PQGPP + G +  G P   G P  P   G     G
Sbjct: 227 VPGQPGIKGDRGFPGEMGPIGPPG-PQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPG 285

Query: 254 PPPPGKPQGPPAQG-----GSKSQSARSPPGKPQGPPQQEGNNPQGPP-------PPAGG 301
            P    P GPP  G     G K +  R P G P GP  +    P G P       PP   
Sbjct: 286 APGIAGPPGPPGFGKPGLPGLKGE--RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNM 343

Query: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
            PQ P+  P     G P P     P+ P
Sbjct: 344 GPQGPKGIPGS--HGLPGPKGETGPAGP 369



 Score =  126 bits (316), Expect = 3e-29
 Identities = 124/388 (31%), Positives = 141/388 (36%), Gaps = 112/388 (28%)

Query: 39  PSPQGGNKPQGPPPP-----PGKPQGPPPQGGNKPQG-PPPPGKPQGPPPQGDKSRSPRS 92
           P P+G   P G P P     PGKP    P G   P+G P   G P  P   G K      
Sbjct: 135 PGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYG 194

Query: 93  PPGKPQG---PPPQGGNQPQGPPPPPG-------------------------------KP 118
            PG+P     P PQG   P GP  PPG                                P
Sbjct: 195 APGRPGERGLPGPQG---PTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGP 251

Query: 119 QGPP----PQGGNRPQGPPPPGK-----------------PQGPPPQGDKS----RSPRS 153
           QGPP    P+G  +P     PG+                 P GPP  G       +  R 
Sbjct: 252 QGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERG 311

Query: 154 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP-PGKPQGPPPQGDK---- 208
           P G P GP   G    QGP   PGKP    P G   PQGP   PG    P P+G+     
Sbjct: 312 PAGLPGGP---GAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAG 368

Query: 209 ---------SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259
                     R S    GKP  P   G + P+G P  PG P+G P  GG       PPG 
Sbjct: 369 PAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPG-PKGDPGVGG-------PPGL 420

Query: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEG-NNPQGPP-----PPAGGNPQQPQAP-PAG 312
           P GP    G+K     +    P+G P   G   P GPP     P + G+P  P  P PAG
Sbjct: 421 P-GPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG 479

Query: 313 -------QPQGPPRPP----QGGRPSRP 329
                   P GPP PP      G P  P
Sbjct: 480 IATKGLNGPTGPPGPPGPRGHSGEPGLP 507



 Score =  126 bits (316), Expect = 3e-29
 Identities = 105/298 (35%), Positives = 119/298 (39%), Gaps = 40/298 (13%)

Query: 36  PQGP----SPQGGNKP-----QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
           PQGP     P+G  KP      G P  PG    P   G   P GPP  GKP  P  +G+ 
Sbjct: 251 PQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGE- 309

Query: 87  SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP-PGKPQGPPPQG 145
               R P G P GP  +G    QGP   PGKP    P G   PQGP   PG    P P+G
Sbjct: 310 ----RGPAGLPGGPGAKG---EQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362

Query: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK---PQGPP----PPGK 198
           +    P  P G P     +G     G P  PGKP    P+G      P+G P    PPG 
Sbjct: 363 ETG--PAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL 420

Query: 199 PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ-PQGPPPPPGKP--------QGPPPQGGN 249
           P    P G K     +    P+G P   G + P GPP  PG P         GPP   G 
Sbjct: 421 PGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI 480

Query: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ----EGNNPQGPPPPAGGNP 303
             +G   P  P GPP   G   +     P  P GPP Q    EG    G  P   G P
Sbjct: 481 ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTP 538



 Score =  122 bits (306), Expect = 4e-28
 Identities = 114/310 (36%), Positives = 126/310 (40%), Gaps = 54/310 (17%)

Query: 37  QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK 96
           +GP P    K Q   P   K +G   +G     GPP P  P+G P        P  PPGK
Sbjct: 32  KGPLPN--TKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHP-------GPSGPPGK 82

Query: 97  PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR-SPRSPP 155
           P       G    G    PG P  P P    +P  P  PGKP    P G K    P   P
Sbjct: 83  P-------GYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLP 135

Query: 156 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215
           G P+GPP        GPP  PG P G    G    QGP     P+G P  G+K       
Sbjct: 136 G-PRGPP--------GPPGIPG-PAGISVPGKPGQQGPTGAPGPRGFP--GEK-----GA 178

Query: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGSK--- 270
           PG P G   Q G    G P  PG+   P PQG   P GPP  GK    G P Q G K   
Sbjct: 179 PGVP-GMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDR 237

Query: 271 ----SQSARSPPGKPQGPPQQEGNNPQG-PPPPAGGNPQQPQAPPA----GQP--QGPPR 319
                     PPG PQGPP + G  P+G   P A G P QP  P      G P   GPP 
Sbjct: 238 GFPGEMGPIGPPG-PQGPPGERG--PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294

Query: 320 PPQGGRPSRP 329
           PP  G+P  P
Sbjct: 295 PPGFGKPGLP 304



 Score =  107 bits (266), Expect = 2e-23
 Identities = 86/242 (35%), Positives = 99/242 (40%), Gaps = 33/242 (13%)

Query: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQG 84
           E  P+ + G P      G    QGP   PGKP    P G   PQGP   PG    P P+G
Sbjct: 309 ERGPAGLPGGP------GAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362

Query: 85  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144
           +    P  P G P      G    +G P   GKP  P   G + P+G P    P+G P  
Sbjct: 363 E--TGPAGPAGYP------GAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGV 414

Query: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPP 204
           G        PPG P    P G     G     G    P   G + P G  PPG P  P  
Sbjct: 415 G-------GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIG--PPGIPGFPGS 465

Query: 205 QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 264
           +GD    S  PPG P G   +G N P GPP PPG      P+G +   G P P  P GPP
Sbjct: 466 KGDP--GSPGPPG-PAGIATKGLNGPTGPPGPPG------PRGHSGEPGLPGPPGPPGPP 516

Query: 265 AQ 266
            Q
Sbjct: 517 GQ 518



 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 69/185 (37%), Positives = 78/185 (42%), Gaps = 37/185 (20%)

Query: 34  GNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP--PQGDKSRSPR 91
           G P  P   G + P+G P  PG P+G P  GG  P G P P  P G    P  +    PR
Sbjct: 386 GKPGYPGKPGLDGPKGNPGLPG-PKGDPGVGG--PPGLPGPVGPAGAKGMPGHNGEAGPR 442

Query: 92  SPPGKP--QGP--PP-----QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142
             PG P  +GP  PP      G     G P PPG P G   +G N P GPP P  P+G  
Sbjct: 443 GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG-PAGIATKGLNGPTGPPGPPGPRGHS 501

Query: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG-KKPQGPPPPGKPQG 201
            +          PG P GPP        GPP PPG  Q   P+G  K  Q P   G P  
Sbjct: 502 GE----------PGLP-GPP--------GPPGPPG--QAVMPEGFIKAGQRPSLSGTPLV 540

Query: 202 PPPQG 206
              QG
Sbjct: 541 SANQG 545


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.139    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,010,352
Number of Sequences: 37866
Number of extensions: 4867451
Number of successful extensions: 219524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1982
Number of HSP's successfully gapped in prelim test: 2206
Number of HSP's that attempted gapping in prelim test: 20199
Number of HSP's gapped (non-prelim): 47047
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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