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Search of human proteins with 41327708
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
(1406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 3034 0.0
gi|112420992 crumbs homolog 2 [Homo sapiens] 766 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 380 e-105
gi|24041035 notch 2 preproprotein [Homo sapiens] 375 e-103
gi|55770876 notch4 preproprotein [Homo sapiens] 354 4e-97
gi|134244285 Notch homolog 3 [Homo sapiens] 351 3e-96
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 338 2e-92
gi|4557679 jagged 1 precursor [Homo sapiens] 335 2e-91
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 316 9e-86
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 306 7e-83
gi|122937283 6720455I24Rik homolog [Homo sapiens] 285 3e-76
gi|148886654 polydom [Homo sapiens] 251 5e-66
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 240 8e-63
gi|110735443 delta-like 1 [Homo sapiens] 236 9e-62
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 232 2e-60
gi|11321571 slit homolog 3 [Homo sapiens] 214 5e-55
gi|4759146 slit homolog 2 [Homo sapiens] 210 9e-54
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 205 2e-52
gi|188528675 slit homolog 1 [Homo sapiens] 197 8e-50
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 192 2e-48
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 187 5e-47
gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens] 184 4e-46
gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens] 184 4e-46
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] 173 1e-42
gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens] 173 1e-42
gi|126091152 cubilin [Homo sapiens] 165 2e-40
gi|110347437 latent transforming growth factor beta binding prot... 158 4e-38
gi|110347412 latent transforming growth factor beta binding prot... 158 4e-38
gi|110347431 latent transforming growth factor beta binding prot... 158 4e-38
gi|66346695 fibrillin 2 precursor [Homo sapiens] 157 5e-38
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 3034 bits (7866), Expect = 0.0
Identities = 1406/1406 (100%), Positives = 1406/1406 (100%)
Query: 1 MALKNINYLLIFYLSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTA 60
MALKNINYLLIFYLSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTA
Sbjct: 1 MALKNINYLLIFYLSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTA 60
Query: 61 NNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQ 120
NNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQ
Sbjct: 61 NNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQ 120
Query: 121 HGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG 180
HGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG
Sbjct: 121 HGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQG 180
Query: 181 RHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ 240
RHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ
Sbjct: 181 RHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ 240
Query: 241 DALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCET 300
DALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCET
Sbjct: 241 DALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCET 300
Query: 301 LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE 360
LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE
Sbjct: 301 LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE 360
Query: 361 KQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYT 420
KQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYT
Sbjct: 361 KQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYT 420
Query: 421 CHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
CHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC
Sbjct: 421 CHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Query: 481 EIATTLSFEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSG 540
EIATTLSFEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSG
Sbjct: 481 EIATTLSFEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSG 540
Query: 541 YIHLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLE 600
YIHLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLE
Sbjct: 541 YIHLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLE 600
Query: 601 SDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISS 660
SDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISS
Sbjct: 601 SDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISS 660
Query: 661 GSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDD 720
GSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDD
Sbjct: 661 GSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDD 720
Query: 721 STGYVIFTLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSP 780
STGYVIFTLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSP
Sbjct: 721 STGYVIFTLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSP 780
Query: 781 KLVVKFVLNDGNVHLISLKIKPYKIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDKQE 840
KLVVKFVLNDGNVHLISLKIKPYKIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDKQE
Sbjct: 781 KLVVKFVLNDGNVHLISLKIKPYKIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDKQE 840
Query: 841 TELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGG 900
TELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGG
Sbjct: 841 TELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGG 900
Query: 901 VCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQ 960
VCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQ
Sbjct: 901 VCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQ 960
Query: 961 ILFRSNGNITRELTNITFGFRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYM 1020
ILFRSNGNITRELTNITFGFRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYM
Sbjct: 961 ILFRSNGNITRELTNITFGFRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYM 1020
Query: 1021 LSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDI 1080
LSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDI
Sbjct: 1021 LSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDI 1080
Query: 1081 YVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQL 1140
YVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQL
Sbjct: 1081 YVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQL 1140
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200
NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC
Sbjct: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHC 1200
Query: 1201 TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG 1260
TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG
Sbjct: 1201 TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG 1260
Query: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQ 1320
NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQ
Sbjct: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQ 1320
Query: 1321 CLCDVAFAGERCEVDLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNKRATQGTYS 1380
CLCDVAFAGERCEVDLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNKRATQGTYS
Sbjct: 1321 CLCDVAFAGERCEVDLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNKRATQGTYS 1380
Query: 1381 PSRQEKEGSRVEMWNLMPPPAMERLI 1406
PSRQEKEGSRVEMWNLMPPPAMERLI
Sbjct: 1381 PSRQEKEGSRVEMWNLMPPPAMERLI 1406
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 766 bits (1979), Expect = 0.0
Identities = 444/1336 (33%), Positives = 655/1336 (49%), Gaps = 146/1336 (10%)
Query: 125 CHQDPIYPVCICPAGYAGRFC--EIDHDECASSPCQNGAVC-QDGID--GYSCFCVPGYQ 179
C DP P C A +G + ++ CA+ PC +GA+C G D G+ C+CVPG+Q
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQ 101
Query: 180 GRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC 239
G C+L++DECAS PC + ATC N RY C CP Y+GV CE+E+DEC S PCL+G +C
Sbjct: 102 GPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSC 161
Query: 240 QDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE 299
D +G++ C CAPG+ G C+L+ DEC SQPC HGG C D N + C+C G+G+ GTHCE
Sbjct: 162 LDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCE 221
Query: 300 TLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSS 359
+ C S PC +NA+C + + ++ C CWPGY+G CE+D +EC S+PCQ G C++ S
Sbjct: 222 REVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSD 281
Query: 360 EKQYGRI-TGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGN 418
YG + P +FS+ A+G++C C PGF G C +V+EC+S PC NGG C++LP
Sbjct: 282 PALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNG 341
Query: 419 YTCHCPFDNLSRTF--------------------------------YGGRDCSDILLGCT 446
+ CHCP T +GGRDCS L GC
Sbjct: 342 FQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ 401
Query: 447 HQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTKGS 506
C TCIP F+ G H + C CP G G C TT S + SV G
Sbjct: 402 GHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPI---QASVPAGGP 458
Query: 507 VCNIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNT-SDG 565
+ +ALRF+T P L R++ ++L L++ + ++ + + ++L + +DG
Sbjct: 459 L-GLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLALNDG 517
Query: 566 EWHFVEVIFAEA-VTLTLIDDSCKEK-CIAKAPTPLESDQSICAFQNSFLGGLPVGMTSN 623
WH VEV+ A + L L + C + C+A P L S S LP G++S
Sbjct: 518 HWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATP--------LPAGISSA 569
Query: 624 GVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKDWCESQPCQS 683
+ +F GCLQD+++D + + E++ NV GC R++ C PC
Sbjct: 570 QLG---------DATFAGCLQDVRVDGHLLLPEDLGE----NVLLGCERREQCRPLPCVH 616
Query: 684 RGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYGDTISLSMFV 743
G C++LW ++CDC RP+ GP C E A FG + F L E G +++S +
Sbjct: 617 GGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELPGPNLTVSFLL 676
Query: 744 RTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLVVKFVLNDGNVHLISLKIKPY 803
RT + +GLLL N + + V+L GR+ P SP +V+ +DG HL+ L P
Sbjct: 677 RTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPD 736
Query: 804 KIELYQSSQNLGFISASTWKIEKGDVIYIGGLPDKQETELNGGFFKGCIQDVRLNNQNLE 863
+++ + G +++GG +++ GG F+GC+QD+RL+ +L
Sbjct: 737 QLQ------------------DLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLP 778
Query: 864 FFPNPTNNASLNPVL-----VNVTQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTS 918
FFP P +N+S L N+T GC ++ C +PC NGG C W+DF C+CPA +
Sbjct: 779 FFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFT 838
Query: 919 GKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFRSNGNITRELTNITF 978
G C + WC PC A C+ V GF C+A A F N + R L ++
Sbjct: 839 GPTCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLLGGLSL 898
Query: 979 GFRTRDANVIILHAEKEP-EFLNISIQDSRLFFQLQSGNSF--YMLSLTSLQSVNDGTWH 1035
FRTRD+ +L A E + +++++ L ++ G+ +L + V DG WH
Sbjct: 899 AFRTRDSEAWLLRAAAGALEGVWLAVRNGSLAGGVRGGHGLPGAVLPIPG-PRVADGAWH 957
Query: 1036 EVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVGDRAIDNIKGLQG 1095
V L+M P + TSRW + +D V L FL+ G I + G
Sbjct: 958 RVRLAMERPAATTSRWLLWLDGAATPVALRGLASDLGFLQG-----PGAVRILLAENFTG 1012
Query: 1096 CLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCE 1155
CL + +GG+ L G +E T + + GC VC +PCLH G C
Sbjct: 1013 CLGRVALGGLPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACR 1072
Query: 1156 DIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRV-AAYHCTCEPGYTGVNCEVD 1214
D++ ++ C+C GW G CE ++D C S PC G C + C C PG+ G C +
Sbjct: 1073 DLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLP 1132
Query: 1215 IDNCQ---SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNG 1271
+ + + + C +G+ C + +C C G+ C+ LP C NG
Sbjct: 1133 VPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA-------NPCLNG 1185
Query: 1272 GNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGER 1331
G C +C+C F+G++CE V GL L L +VA
Sbjct: 1186 GTCRAAGGVSECICNARFSGQFCE-----------VAKGLPLPLPFP---LLEVAV---- 1227
Query: 1332 CEVDLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNK-RATQGTYSPSRQEKEGSR 1390
A LL+LLL +++ ++ + K R ++GTYSPS+QE G+R
Sbjct: 1228 ------------------PAACACLLLLLLGLLSGILAARKRRQSEGTYSPSQQEVAGAR 1269
Query: 1391 VEMWNLMPPPAMERLI 1406
+EM +++ P ERLI
Sbjct: 1270 LEMDSVLKVPPEERLI 1285
Score = 91.3 bits (225), Expect = 6e-18
Identities = 52/152 (34%), Positives = 67/152 (44%), Gaps = 5/152 (3%)
Query: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG-YSC 172
C + C H G C C C G+ G CE D C S+PC G C DG + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRFEC 1118
Query: 173 FCVPGYQGRHCDLEVD--ECASD-PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECW 229
C PG+ G C L V EC+ + C + + C C C +G C++ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 230 SQPCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
+ PCLNG TC+ A G C C F G CE+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 89.7 bits (221), Expect = 2e-17
Identities = 49/154 (31%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Query: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133
C +PC C + +F C C PG+ G CE + C C G CH P
Sbjct: 1060 CAPSPCLHDGACRDLFD--AFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRF 1116
Query: 134 -CICPAGYAGRFCE--IDHDECASS-PCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
C CP G+ G C + EC+ + C +G+ C+ G +C C+ G G+ C +
Sbjct: 1117 ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCEL 223
C ++PC N TC G CIC +SG CE+
Sbjct: 1177 CEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 82.8 bits (203), Expect = 2e-15
Identities = 46/155 (29%), Positives = 66/155 (42%), Gaps = 7/155 (4%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
C + C ++ C+D C+C C+ DPC S PC C P R
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEG--PRCEAHVDPCHSAPC-ARGRCHTHPDGR- 1115
Query: 94 FLCKCPPGYSGTICETTIGS--CGKN-SCQHGGICHQDPIYPVCICPAGYAGRFCEIDHD 150
F C+CPPG+ G C + S C N +C G C C C G AG+ C++
Sbjct: 1116 FECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
Query: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL 185
C ++PC NG C+ C C + G+ C++
Sbjct: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 40.0 bits (92), Expect = 0.016
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 35 LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94
L+ +C + S C+ S +CSC + + C PC +NPC TC G
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAG--QRCQVPTLPCEANPCLNGGTCRAAGGVSE- 1196
Query: 95 LCKCPPGYSGTICETTIG 112
C C +SG CE G
Sbjct: 1197 -CICNARFSGQFCEVAKG 1213
Score = 38.5 bits (88), Expect = 0.046
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Query: 62 NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQH 121
NL C + +D C +PC TC+ T + F C CP ++G C + C C
Sbjct: 800 NLTAGCVS-EDMCSPDPCFNGGTCLVTWND--FHCTCPANFTGPTCAQQLW-CPGQPCLP 855
Query: 122 GGICHQDPIYPVCICPAGY 140
C + P VC+ A +
Sbjct: 856 PATCEEVPDGFVCVAEATF 874
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 380 bits (977), Expect = e-105
Identities = 191/513 (37%), Positives = 253/513 (49%), Gaps = 73/513 (14%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C++N C S +C + +TC D C C L ++ D C SNPC + C
Sbjct: 332 CSENIDDCASAACFHGATCHDRVASFYCECPHGRTGL---LCHLNDACISNPCNEGSNCD 388
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSC--GKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
P +C CP GY+G C + C G N C+H G C C C GY G
Sbjct: 389 TNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR 448
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL------------------- 185
CEID +EC S+PCQN A C D I + C C+PGY+G HC++
Sbjct: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
Query: 186 -------------------EVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEID 226
+VDECAS PCKN A CL+ YTC+C Y+G +CE++ID
Sbjct: 509 INEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDID 568
Query: 227 ECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSC 286
EC PC G +C+D + + C C PG+ G HCE N +EC+SQPC HGG C D +N Y C
Sbjct: 569 ECDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLC 627
Query: 287 NCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSN 346
C G TG +CE + C S PC ++ TC D +D Y C C PGYTG+ C I+++EC N
Sbjct: 628 FCL-KGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGN 685
Query: 347 PCQSNGECVE------------LSSEKQYGRITGLPSSFSYHEA-----SGYVCICQPGF 389
PC + G C + + S+ H A +GY C C PG+
Sbjct: 686 PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGW 745
Query: 390 TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQ 449
+G +C+ + NEC SNPC NGGTC+++ Y C C R + G +C + C
Sbjct: 746 SGTNCDINNNECESNPCVNGGTCKDMTSGYVCTC------REGFSGPNCQTNINECASNP 799
Query: 450 CLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
CLN GTCI D G+ C C YTG+ CE+
Sbjct: 800 CLNQGTCI----DDVAGYKCNCLLPYTGATCEV 828
Score = 375 bits (962), Expect = e-103
Identities = 171/456 (37%), Positives = 244/456 (53%), Gaps = 36/456 (7%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C+SN CQN++TC D + C C + C+ D C S+PC + C+
Sbjct: 449 CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVH--CEVNTDECASSPCLHNGRCL 506
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ E F C+CP G++G +C+ + C C++G C P C+C GY G CE
Sbjct: 507 DKINE--FQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
+D DEC PC G+ C+DG+ ++C C PGY G HC+ ++EC+S PC++ TC +
Sbjct: 565 VDIDECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDN 623
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
Y C C +G NCE+ +D+C S PC +G TC D + Y C C PG+ G C +N DEC
Sbjct: 624 AYLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKIDGYECACEPGYTGSMCNINIDEC 682
Query: 267 ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
A PC +GG C DG N ++C C G+ C + + C S PC + A C DS++ Y C
Sbjct: 683 AGNPCHNGGTCEDGINGFTCRCP-EGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYKCD 740
Query: 327 CWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQ 386
C PG++G C+I+ NEC SNPC + G C +++S GYVC C+
Sbjct: 741 CDPGWSGTNCDINNNECESNPCVNGGTCKDMTS--------------------GYVCTCR 780
Query: 387 PGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCT 446
GF+G +C+ ++NEC+SNPC N GTC + Y C+C Y G C +L C
Sbjct: 781 EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLP------YTGATCEVVLAPCA 834
Query: 447 HQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
C N G C + FSC+CP+G+ G CE+
Sbjct: 835 PSPCRNGGEC--RQSEDYESFSCVCPTGWQGQTCEV 868
Score = 362 bits (930), Expect = 1e-99
Identities = 173/457 (37%), Positives = 240/457 (52%), Gaps = 39/457 (8%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C N C S C++ TC+D +DN C +C+ D C S+PC S TC+
Sbjct: 600 CETNINECSSQPCRHGGTCQD--RDNAYLCFCLKGTTGPNCEINLDDCASSPCD-SGTCL 656
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ + C C PGY+G++C I C N C +GG C C CP GY C
Sbjct: 657 DKID--GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCL 714
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
+ +EC S+PC +GA C+D ++GY C C PG+ G +CD+ +EC S+PC N TC +
Sbjct: 715 SEVNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTS 773
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
Y C C +SG NC+ I+EC S PCLN TC D + Y C+C + G CE+ C
Sbjct: 774 GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC 833
Query: 267 ASQPCLHGGLCVDGEN--RYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
A PC +GG C E+ +SC C +G+ G CE + C PC + A+C+++ Y
Sbjct: 834 APSPCRNGGECRQSEDYESFSCVCP-TGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
Query: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
CHC GY+G CE D+++C NPC + G C + G+ ++F C
Sbjct: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD-----------GINTAF---------CD 932
Query: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
C PGF G CEED+NEC+S+PC+NG C + +YTC CP + G C +
Sbjct: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP------AGFSGIHCENNTPD 986
Query: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
CT C N GTC+ DG + F+CLCP G+TGS C+
Sbjct: 987 CTESSCFNGGTCV----DGINSFTCLCPPGFTGSYCQ 1019
Score = 358 bits (919), Expect = 2e-98
Identities = 179/515 (34%), Positives = 254/515 (49%), Gaps = 75/515 (14%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSNPCQGSAT 84
C +N C N+C+N C D +C C T +D D + N CQ T
Sbjct: 254 CEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ--LMPNACQNGGT 311
Query: 85 CVNTPG------------------------------------ERSFLCKCPPGYSGTICE 108
C NT G SF C+CP G +G +C
Sbjct: 312 CHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCH 371
Query: 109 TTIGSCGKNSCQHGGICHQDPI--YPVCICPAGYAGRFCEIDHDECA--SSPCQNGAVCQ 164
+C N C G C +P+ +C CP+GY G C D DEC+ ++PC++ C
Sbjct: 372 LN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCI 430
Query: 165 DGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELE 224
+ + + C C+ GY G C+++V+EC S+PC+N+ATCL++IG + CIC Y GV+CE+
Sbjct: 431 NTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN 490
Query: 225 IDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRY 284
DEC S PCL+ C D + + C+C GF G C+ + DECAS PC +G C+DG N Y
Sbjct: 491 TDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTY 550
Query: 285 SCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECN 344
+C CT G+TGTHCE + C PCH +C+D V +TC C PGYTG CE ++NEC+
Sbjct: 551 TCVCT-EGYTGTHCEVDIDECDPDPCH-YGSCKDGVATFTCLCRPGYTGHHCETNINECS 608
Query: 345 SNPCQSNGECVELSSEKQYGRITG-----------------LPSSFSYHEASGYVCICQP 387
S PC+ G C + + + G S + GY C C+P
Sbjct: 609 SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 668
Query: 388 GFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTH 447
G+TG C +++EC+ NPC NGGTCE+ +TC CP Y C + C
Sbjct: 669 GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCP------EGYHDPTCLSEVNECNS 722
Query: 448 QQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
C+ +G C +D +G+ C C G++G+ C+I
Sbjct: 723 NPCV-HGAC----RDSLNGYKCDCDPGWSGTNCDI 752
Score = 356 bits (914), Expect = 8e-98
Identities = 187/569 (32%), Positives = 251/569 (44%), Gaps = 124/569 (21%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C N C SN C N TC D C+C C+ + PC +PC+ C
Sbjct: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNC--LLPYTGATCEVVLAPCAPSPCRNGGECR 845
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ SF C CP G+ G CE I C + C+HG C C C AGY+GR CE
Sbjct: 846 QSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE 905
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
D D+C +PC NG C DGI+ C C+PG++G C+ +++ECASDPC+N A C + +
Sbjct: 906 TDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVD 965
Query: 207 RYTCICPHNYSGVNCEL--------------------------------------EIDEC 228
YTC CP +SG++CE +++EC
Sbjct: 966 SYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNEC 1025
Query: 229 WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP------------------ 270
SQPCL+G TCQD G+Y C C G+ G +C+ C S P
Sbjct: 1026 DSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCEC 1085
Query: 271 ------------------------------CLHGGLCVDGENRYSCNCTGSGFTGTHCET 300
C HGGLCVD N + C C +G+TG++CE
Sbjct: 1086 PSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQ-AGYTGSYCED 1144
Query: 301 LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSS- 359
L+ C PC N ATC D + Y+C C GY G C +++EC S+PCQ+ G C++L +
Sbjct: 1145 LVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNT 1204
Query: 360 ---------------------EKQYGRITGLPSSFS----YHEASGYVCICQPGFTGIHC 394
++ P F+ + GY C C PGF G C
Sbjct: 1205 YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERC 1264
Query: 395 EEDVNECSSNPCQNGGT--CENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLN 452
E DVNEC SNPC GT C ++ C C R + GR C ++ GC + C N
Sbjct: 1265 EGDVNECLSNPCDARGTQNCVQRVNDFHCEC------RAGHTGRRCESVINGCKGKPCKN 1318
Query: 453 NGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
GTC + GF C CP+G+ G+ CE
Sbjct: 1319 GGTCAV-ASNTARGFICKCPAGFEGATCE 1346
Score = 354 bits (908), Expect = 4e-97
Identities = 173/461 (37%), Positives = 238/461 (51%), Gaps = 40/461 (8%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
S CN N C N C N TC+D C C + + D C + + C SNPC A
Sbjct: 673 SMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYH--DPTCLSEVNECNSNPCVHGAC 730
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
+ G + C C PG+SGT C+ C N C +GG C VC C G++G
Sbjct: 731 RDSLNG---YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPN 787
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN- 203
C+ + +ECAS+PC N C D + GY C C+ Y G C++ + CA PC+N C
Sbjct: 788 CQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
Query: 204 -EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN 262
+ ++C+CP + G CE++I+EC PC +GA+CQ+ G Y C C G+ G +CE +
Sbjct: 848 EDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
Query: 263 TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
D+C PC +GG C DG N C+C GF GT CE + C S PC N A C D VD+
Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCL-PGFRGTFCEEDINECASDPCRNGANCTDCVDS 966
Query: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
YTC C G++G CE + +C + C + G CV+ G+ S +
Sbjct: 967 YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD-----------GINS---------FT 1006
Query: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDIL 442
C+C PGFTG +C+ DVNEC S PC +GGTC++ G+Y C CP Y G +C +++
Sbjct: 1007 CLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQG------YTGPNCQNLV 1060
Query: 443 LGCTHQQCLNNGTCIP-HFQDGQHGFSCLCPSGYTGSLCEI 482
C C N G C H Q + C CPSG+TG C++
Sbjct: 1061 HWCDSSPCKNGGKCWQTHTQ-----YRCECPSGWTGLYCDV 1096
Score = 328 bits (841), Expect = 2e-89
Identities = 165/494 (33%), Positives = 235/494 (47%), Gaps = 79/494 (15%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
CL+N C+N TC D + C K C DPC SNPC C+ P E S
Sbjct: 106 CLTNPCRNGGTC-DLLTLTEYKCRCPPGWSGKSC-QQADPCASNPCANGGQCL--PFEAS 161
Query: 94 FLCKCPPGYSGTICETTIGSCGKNS--CQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE 151
++C CPP + G C + CG+ C+HGG CH + C+C A + G CE +
Sbjct: 162 YICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP 221
Query: 152 CASSPCQNGAVCQ-DGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 210
C+ SPCQNG C+ G + C C+PG+ G++C+ +D+C + CKN C++ + Y C
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC 281
Query: 211 ICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
CP ++G C ++DEC P C NG TC + G Y C C G+ G+ C N D+CAS
Sbjct: 282 RCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
Query: 269 QPCLHGGLCVDGENRYSCNC----TG---------------------------------- 290
C HG C D + C C TG
Sbjct: 342 AACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCP 401
Query: 291 SGFTGTHCETLMPLC--WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPC 348
SG+TG C + C + PC + C +++ ++ C C GYTG +CEID+NEC SNPC
Sbjct: 402 SGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPC 461
Query: 349 QSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQN 408
Q++ C++ E Q CIC PG+ G+HCE + +EC+S+PC +
Sbjct: 462 QNDATCLDQIGEFQ--------------------CICMPGYEGVHCEVNTDECASSPCLH 501
Query: 409 GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468
G C + + C CP T + G C + C C N C+ DG + ++
Sbjct: 502 NGRCLDKINEFQCECP------TGFTGHLCQYDVDECASTPCKNGAKCL----DGPNTYT 551
Query: 469 CLCPSGYTGSLCEI 482
C+C GYTG+ CE+
Sbjct: 552 CVCTEGYTGTHCEV 565
Score = 325 bits (834), Expect = 1e-88
Identities = 164/468 (35%), Positives = 230/468 (49%), Gaps = 40/468 (8%)
Query: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
C++ TC + C C A + +C+ PC +PCQ TC T G+ + C C
Sbjct: 189 CRHGGTCHNEVGSYRCVCR--ATHTGPNCERPYVPCSPSPCQNGGTCRPT-GDVTHECAC 245
Query: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP-- 156
PG++G CE I C N+C++GG C C CP + G++C D DEC P
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNA 305
Query: 157 CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216
CQNG C + GY+C CV G+ G C +D+CAS C + ATC + + + C CPH
Sbjct: 306 CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR 365
Query: 217 SGVNCELEIDECWSQPCLNGATC--QDALGAYFCDCAPGFLGDHCELNTDECA--SQPCL 272
+G+ C L D C S PC G+ C G C C G+ G C + DEC+ + PC
Sbjct: 366 TGLLCHLN-DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCE 424
Query: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT 332
H G C++ + C C G+TG CE + C S PC N+ATC D + + C C PGY
Sbjct: 425 HAGKCINTLGSFECQCL-QGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE 483
Query: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA-------------- 378
G CE++ +EC S+PC NG C++ +E Q TG ++
Sbjct: 484 GVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKC 543
Query: 379 ----SGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYG 434
+ Y C+C G+TG HCE D++EC +PC + G+C++ +TC C R Y
Sbjct: 544 LDGPNTYTCVCTEGYTGTHCEVDIDECDPDPC-HYGSCKDGVATFTCLC------RPGYT 596
Query: 435 GRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
G C + C+ Q C + GTC QD + + C C G TG CEI
Sbjct: 597 GHHCETNINECSSQPCRHGGTC----QDRDNAYLCFCLKGTTGPNCEI 640
Score = 322 bits (824), Expect = 2e-87
Identities = 167/482 (34%), Positives = 223/482 (46%), Gaps = 58/482 (12%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ +FC ++ C S+ C+N + C D C+C + + C+N C + C
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIH--CENNTPDCTESSCFNG 995
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
TCV+ G SF C CPPG++G+ C+ + C C HGG C C CP GY G
Sbjct: 996 GTCVD--GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTG 1053
Query: 143 RFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC----------AS 192
C+ C SSPC+NG C Y C C G+ G +CD+ C +
Sbjct: 1054 PNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVA 1113
Query: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAP 252
C++ C++ + C C Y+G CE +DEC PC NGATC D LG Y C C
Sbjct: 1114 RLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVA 1173
Query: 253 GFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM--------PL 304
G+ G +C DEC S PC +GG C+D N Y C+C G G HCE + P+
Sbjct: 1174 GYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCP-RGTQGVHCEINVDDCNPPVDPV 1232
Query: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNG--ECVELSSEKQ 362
S C NN TC D V Y+C C PG+ G +CE D+NEC SNPC + G CV+
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ------ 1286
Query: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTC---ENLPGNY 419
+ + C C+ G TG CE +N C PC+NGGTC N +
Sbjct: 1287 --------------RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGF 1332
Query: 420 TCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSL 479
C CP + G C + C +CLN GTCI G +CLC +TG
Sbjct: 1333 ICKCP------AGFEGATCENDARTCGSLRCLNGGTCI----SGPRSPTCLCLGPFTGPE 1382
Query: 480 CE 481
C+
Sbjct: 1383 CQ 1384
Score = 286 bits (733), Expect = 7e-77
Identities = 160/478 (33%), Positives = 226/478 (47%), Gaps = 47/478 (9%)
Query: 38 SCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC--VNTPGERSFL 95
+C N C+ + C C + C + +PC S PC+ + TC V+ G +
Sbjct: 30 TCLNGGKCEAANGTEACVCGGAF--VGPRCQD-PNPCLSTPCKNAGTCHVVDRRGVADYA 86
Query: 96 CKCPPGYSGTICETTI-GSCGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEIDHDECA 153
C C G+SG +C T + +C N C++GG C + C CP G++G+ C+ D CA
Sbjct: 87 CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCA 145
Query: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDP--CKNEATCLNEIGRYTCI 211
S+PC NG C Y C C P + G C +V+EC P C++ TC NE+G Y C+
Sbjct: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCV 205
Query: 212 CPHNYSGVNCELEIDECWSQPCLNGATCQDALGA-YFCDCAPGFLGDHCELNTDECASQP 270
C ++G NCE C PC NG TC+ + C C PGF G +CE N D+C
Sbjct: 206 CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNN 265
Query: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP--CHNNATCEDSVDNYTCHCW 328
C +GG CVDG N Y+C C +TG +C + C P C N TC ++ Y C C
Sbjct: 266 CKNGGACVDGVNTYNCRCPPE-WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCV 324
Query: 329 PGYTGAQCEIDLNECNSNPCQSNGEC----VELSSEKQYGRITGL--------------- 369
G+TG C ++++C S C C E +GR TGL
Sbjct: 325 NGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGR-TGLLCHLNDACISNPCNE 383
Query: 370 PSSFSYHEASGY-VCICQPGFTGIHCEEDVNECS--SNPCQNGGTCENLPGNYTCHCPFD 426
S+ + +G +C C G+TG C +DV+ECS +NPC++ G C N G++ C C
Sbjct: 384 GSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQC--- 440
Query: 427 NLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIAT 484
Y G C + C C N+ TC+ + F C+C GY G CE+ T
Sbjct: 441 ---LQGYTGPRCEIDVNECVSNPCQNDATCLDQIGE----FQCICMPGYEGVHCEVNT 491
Score = 186 bits (473), Expect = 1e-46
Identities = 75/197 (38%), Positives = 112/197 (56%), Gaps = 8/197 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
+ +N C +PC HG +C++ + Y C C G+SG++CE +ID+C NPC +G +C+D +
Sbjct: 868 VDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGIN 927
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
C C PG+ G CE DI+ C S C NGA C + Y+C C F+G C +
Sbjct: 928 TAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNT--- 984
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
+ T +C+NGG C + C+C PGFTG +C+ D++EC S PC++GG CQD
Sbjct: 985 ----PDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGC 1040
Query: 1317 NKFQCLCDVAFAGERCE 1333
++C C + G C+
Sbjct: 1041 GSYRCTCPQGYTGPNCQ 1057
Score = 181 bits (458), Expect = 6e-45
Identities = 77/197 (39%), Positives = 113/197 (57%), Gaps = 8/197 (4%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYH 1199
+N C+S PC HGG C+D ++Y C C G +G +CE+N+D+C S+PC G C D++ Y
Sbjct: 604 INECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYE 663
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
C CEPGYTG C ++ID C + C NG TC NG++C C + C
Sbjct: 664 CACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSE------- 716
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
NE + C +G C + KC C PG++G C+ + +EC S+PCVNGG C+D+ + +
Sbjct: 717 VNECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGY 775
Query: 1320 QCLCDVAFAGERCEVDL 1336
C C F+G C+ ++
Sbjct: 776 VCTCREGFSGPNCQTNI 792
Score = 180 bits (457), Expect = 7e-45
Identities = 81/202 (40%), Positives = 112/202 (55%), Gaps = 9/202 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVA 1196
+ +N C SNPC + C D + C C G+ G HCE+N DEC S+PC+H G C D++
Sbjct: 451 IDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
+ C C G+TG C+ D+D C S C NGA C+ N Y+C+C +TG C
Sbjct: 511 EFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE------ 564
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
V +E C+ G +C + C+CRPG+TG CE +I+EC+S PC +GG CQD
Sbjct: 565 -VDIDECDPDPCHYG-SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRD 622
Query: 1317 NKFQCLCDVAFAGERCEVDLAD 1338
N + C C G CE++L D
Sbjct: 623 NAYLCFCLKGTTGPNCEINLDD 644
Score = 178 bits (451), Expect = 4e-44
Identities = 79/197 (40%), Positives = 105/197 (53%), Gaps = 10/197 (5%)
Query: 1143 CNSNPCLHGGNCE--DIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYH 1199
C +PC +GG C + Y S+ C CP GW G+ CE++I+EC +PC HG +C + Y
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
C C+ GY+G NCE DID+C+ + C NG +C N C C F G FC +
Sbjct: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDI------ 946
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
NE + C NG NCT+ C C GF+G CE + +C C NGG C D +N F
Sbjct: 947 -NECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSF 1005
Query: 1320 QCLCDVAFAGERCEVDL 1336
CLC F G C+ D+
Sbjct: 1006 TCLCPPGFTGSYCQHDV 1022
Score = 176 bits (446), Expect = 1e-43
Identities = 77/207 (37%), Positives = 114/207 (55%), Gaps = 9/207 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
+ ++ C NPC +GG CED + + C CP G+ C ++EC SNPC+HG C D +
Sbjct: 677 INIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG 736
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Y C C+PG++G NC+++ + C+S+ C NG TC T+GY C C F+G C+ +
Sbjct: 737 YKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI---- 792
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQ--DL 1315
NE + C N G C + KC C +TG CE + CA PC NGG C+ +
Sbjct: 793 ---NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSED 849
Query: 1316 LNKFQCLCDVAFAGERCEVDLADDLIS 1342
F C+C + G+ CEVD+ + ++S
Sbjct: 850 YESFSCVCPTGWQGQTCEVDINECVLS 876
Score = 176 bits (446), Expect = 1e-43
Identities = 93/253 (36%), Positives = 125/253 (49%), Gaps = 49/253 (19%)
Query: 1135 TGC-LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCS 1192
T C + N C SNPC++GG C+D+ S Y C+C G+SG +C+ NI+EC SNPC++ G C
Sbjct: 748 TNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCI 807
Query: 1193 DRVAAYHCTCEPGYTGVNCEV--------------------------------------- 1213
D VA Y C C YTG CEV
Sbjct: 808 DDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCE 867
Query: 1214 -DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGG 1272
DI+ C C +GA+C + GY C C ++G+ C T + + N C+NGG
Sbjct: 868 VDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCE------TDIDDCRPN-PCHNGG 920
Query: 1273 NCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
+CT+ C C PGF G +CE+DI+ECASDPC NG C D ++ + C C F+G C
Sbjct: 921 SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980
Query: 1333 EVDLADDLISDIF 1345
E + D S F
Sbjct: 981 ENNTPDCTESSCF 993
Score = 172 bits (437), Expect = 2e-42
Identities = 76/190 (40%), Positives = 104/190 (54%), Gaps = 8/190 (4%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTC 1202
C S PC +G C D ++Y C C G++G HCE++IDEC +PC +G+C D VA + C C
Sbjct: 532 CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLC 591
Query: 1203 EPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNE 1262
PGYTG +CE +I+ C S C +G TC N Y C C TG C + ++
Sbjct: 592 RPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCE-------INLDD 644
Query: 1263 KTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCL 1322
+ C + G C + +C C PG+TG C +IDECA +PC NGG C+D +N F C
Sbjct: 645 CASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR 703
Query: 1323 CDVAFAGERC 1332
C + C
Sbjct: 704 CPEGYHDPTC 713
Score = 171 bits (433), Expect = 5e-42
Identities = 77/205 (37%), Positives = 109/205 (53%), Gaps = 12/205 (5%)
Query: 1137 CLQLNVCNSNPCLHGGNCED--IYSSYHCSCPLGWSGKHCELNIDECF--SNPCIH-GNC 1191
C + C SNPC G NC+ + C+CP G++G C ++DEC +NPC H G C
Sbjct: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
Query: 1192 SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
+ + ++ C C GYTG CE+D++ C S+ C N ATC+ + C+C + G C
Sbjct: 430 INTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCE- 488
Query: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
V +E + C + G C + E +C C GFTG C+ D+DECAS PC NG
Sbjct: 489 ------VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK 542
Query: 1312 CQDLLNKFQCLCDVAFAGERCEVDL 1336
C D N + C+C + G CEVD+
Sbjct: 543 CLDGPNTYTCVCTEGYTGTHCEVDI 567
Score = 164 bits (416), Expect = 4e-40
Identities = 104/317 (32%), Positives = 145/317 (45%), Gaps = 42/317 (13%)
Query: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC----QDALGAYFC 248
+ C N C G C+C + G C+ + + C S PC N TC + + Y C
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYAC 87
Query: 249 DCAPGFLGDHCELNTDE-CASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPLCW 306
CA GF G C D C + PC +GG C + Y C C G++G C+ P C
Sbjct: 88 SCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCP-PGWSGKSCQQADP-CA 145
Query: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP--CQSNGEC-VELSSEKQY 363
S PC N C +Y CHC P + G C D+NEC P C+ G C E+ S +
Sbjct: 146 SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCV 205
Query: 364 GRITG---------LPSSFSYHEASG---------YVCICQPGFTGIHCEEDVNECSSNP 405
R T +P S S + G + C C PGFTG +CEE++++C N
Sbjct: 206 CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNN 265
Query: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGC--THQQCLNNGTCIPHFQDG 463
C+NGG C + Y C CP + + G+ C++ + C C N GTC H G
Sbjct: 266 CKNGGACVDGVNTYNCRCPPE------WTGQYCTEDVDECQLMPNACQNGGTC--HNTHG 317
Query: 464 QHGFSCLCPSGYTGSLC 480
G++C+C +G+TG C
Sbjct: 318 --GYNCVCVNGWTGEDC 332
Score = 163 bits (413), Expect = 9e-40
Identities = 75/206 (36%), Positives = 106/206 (51%), Gaps = 12/206 (5%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
C + C +GG C D +S+ C CP G++G +C+ +++EC S PC+HG C D +Y CT
Sbjct: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC-- 1259
C GYTG NC+ + C S C NG C Y C C +TG +C +PS C
Sbjct: 1047 CPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD---VPSVSCEV 1103
Query: 1260 -----GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
G + L C +GG C + C C+ G+TG +CE +DEC+ PC NG C D
Sbjct: 1104 AAQRQGVDVARL-CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTD 1162
Query: 1315 LLNKFQCLCDVAFAGERCEVDLADDL 1340
L + C C + G C ++ + L
Sbjct: 1163 YLGGYSCKCVAGYHGVNCSEEIDECL 1188
Score = 160 bits (406), Expect = 6e-39
Identities = 74/210 (35%), Positives = 108/210 (51%), Gaps = 18/210 (8%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
+N C+S PCLHGG C+D SY C+CP G++G +C+ + C S+PC +G C Y
Sbjct: 1022 VNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQY 1081
Query: 1199 HCTCEPGYTGVNCEVDIDNCQ----------SHQCANGATCISHTNGYSCLCFGNFTGKF 1248
C C G+TG+ C+V +C+ + C +G C+ N + C C +TG +
Sbjct: 1082 RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSY 1141
Query: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
C +E + C NG CT++ C C G+ G C ++IDEC S PC N
Sbjct: 1142 CED-------LVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQN 1194
Query: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
GG C DL N ++C C G CE+++ D
Sbjct: 1195 GGTCLDLPNTYKCSCPRGTQGVHCEINVDD 1224
Score = 160 bits (405), Expect = 8e-39
Identities = 97/263 (36%), Positives = 127/263 (48%), Gaps = 43/263 (16%)
Query: 230 SQP---CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLC--VD--GEN 282
SQP CLNG C+ A G C C F+G C+ + + C S PC + G C VD G
Sbjct: 25 SQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVA 83
Query: 283 RYSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATCE-DSVDNYTCHCWPGYTGAQCEIDL 340
Y+C+C GF+G C T L C + PC N TC+ ++ Y C C PG++G C+
Sbjct: 84 DYACSC-ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QA 141
Query: 341 NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE 400
+ C SNPC + G+C+ EAS Y+C C P F G C +DVNE
Sbjct: 142 DPCASNPCANGGQCLPF-------------------EAS-YICHCPPSFHGPTCRQDVNE 181
Query: 401 CSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP 458
C P C++GGTC N G+Y C C R + G +C + C+ C N GTC P
Sbjct: 182 CGQKPGLCRHGGTCHNEVGSYRCVC------RATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 459 HFQDGQHGFSCLCPSGYTGSLCE 481
G C C G+TG CE
Sbjct: 236 ---TGDVTHECACLPGFTGQNCE 255
Score = 158 bits (399), Expect = 4e-38
Identities = 76/199 (38%), Positives = 100/199 (50%), Gaps = 13/199 (6%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYH-- 1199
C S C HG C D +S++C CP G +G C LN D C SNPC G NC
Sbjct: 339 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKAI 397
Query: 1200 CTCEPGYTGVNCEVDIDNCQ--SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
CTC GYTG C D+D C ++ C + CI+ + C C +TG C
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE------- 450
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
+ NE + C N C + E +C+C PG+ G CE + DECAS PC++ G C D +N
Sbjct: 451 IDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 1318 KFQCLCDVAFAGERCEVDL 1336
+FQC C F G C+ D+
Sbjct: 511 EFQCECPTGFTGHLCQYDV 529
Score = 157 bits (396), Expect = 9e-38
Identities = 76/217 (35%), Positives = 102/217 (47%), Gaps = 26/217 (11%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC----------FSNPCIHGN-C 1191
C+S+PC +GG C ++ Y C CP GW+G +C++ C + C HG C
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
Query: 1192 SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
D +HC C+ GYTG CE +D C C NGATC + GYSC C + G C +
Sbjct: 1123 VDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSE 1182
Query: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--------AS 1303
+E + C NGG C + KC C G G CE ++D+C S
Sbjct: 1183 EI-------DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRS 1235
Query: 1304 DPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
C N G C D + + C C F GERCE D+ + L
Sbjct: 1236 PKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECL 1272
Score = 155 bits (393), Expect = 2e-37
Identities = 75/201 (37%), Positives = 103/201 (51%), Gaps = 13/201 (6%)
Query: 1141 NVCNSNPCLHGGNCEDI-YSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
N C +NPC +GG C+ + + Y C CP GWSGK C+ D C SNPC +G C A+Y
Sbjct: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASY 162
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
C C P + G C D++ C C +G TC + Y C+C TG C + +P
Sbjct: 163 ICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC 222
Query: 1257 TVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
+ C NGG C +C C PGFTG+ CE++ID+C + C NGG C D
Sbjct: 223 SPS-------PCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDG 275
Query: 1316 LNKFQCLCDVAFAGERCEVDL 1336
+N + C C + G+ C D+
Sbjct: 276 VNTYNCRCPPEWTGQYCTEDV 296
Score = 147 bits (372), Expect = 5e-35
Identities = 76/241 (31%), Positives = 105/241 (43%), Gaps = 47/241 (19%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP--CIH-GNCSD 1193
C Q + C SNPC +GG C +SY C CP + G C +++EC P C H G C +
Sbjct: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHN 197
Query: 1194 RVAAYHCTCE---------------------------------------PGYTGVNCEVD 1214
V +Y C C PG+TG NCE +
Sbjct: 198 EVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEEN 257
Query: 1215 IDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC 1274
ID+C + C NG C+ N Y+C C +TG++C + + N C NGG C
Sbjct: 258 IDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN-----ACQNGGTC 312
Query: 1275 TEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
C+C G+TGE C ++ID+CAS C +G C D + F C C G C +
Sbjct: 313 HNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHL 372
Query: 1335 D 1335
+
Sbjct: 373 N 373
Score = 147 bits (372), Expect = 5e-35
Identities = 76/207 (36%), Positives = 97/207 (46%), Gaps = 21/207 (10%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
C+ +PC +G C D Y C C G+ G +C IDEC S+PC +G C D Y C+
Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
Query: 1202 CEPGYTGVNCEVDIDNC--------QSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR 1253
C G GV+CE+++D+C +S +C N TC+ GYSC C F G+ C
Sbjct: 1209 CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV 1268
Query: 1254 LPSTVCGNEKTNLTCYNGG--NCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
NE + C G NC + + C CR G TG CE I+ C PC NGG
Sbjct: 1269 -------NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGT 1321
Query: 1312 CQDLLNK---FQCLCDVAFAGERCEVD 1335
C N F C C F G CE D
Sbjct: 1322 CAVASNTARGFICKCPAGFEGATCEND 1348
Score = 147 bits (372), Expect = 5e-35
Identities = 77/211 (36%), Positives = 103/211 (48%), Gaps = 25/211 (11%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI----------- 1187
+++ C S+PC +GG C D+ ++Y CSCP G G HCE+N+D+C NP +
Sbjct: 1183 EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC--NPPVDPVSRSPKCFN 1240
Query: 1188 HGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQC-ANGA-TCISHTNGYSCLCFGNFT 1245
+G C D+V Y CTC PG+ G CE D++ C S+ C A G C+ N + C C T
Sbjct: 1241 NGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHT 1300
Query: 1246 GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELK---CMCRPGFTGEWCEKDIDECA 1302
G+ C S + G + C NGG C + C C GF G CE D C
Sbjct: 1301 GRRCE-----SVINGCK--GKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCG 1353
Query: 1303 SDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
S C+NGG C CLC F G C+
Sbjct: 1354 SLRCLNGGTCISGPRSPTCLCLGPFTGPECQ 1384
Score = 135 bits (341), Expect = 2e-31
Identities = 108/388 (27%), Positives = 146/388 (37%), Gaps = 77/388 (19%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTAN------NLDKDCDNMKDPCFSNP-C 79
C++ CLS+ CQN TC D CSC N+D DC+ DP +P C
Sbjct: 1180 CSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVD-DCNPPVDPVSRSPKC 1238
Query: 80 QGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGI--CHQDPIYPVCICP 137
+ TCV+ G + C CPPG+ G CE + C N C G C Q C C
Sbjct: 1239 FNNGTCVDQVG--GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECR 1296
Query: 138 AGYAGRFCEIDHDECASSPCQNGAVC---QDGIDGYSCFCVPGYQGRHCDLEVDECASDP 194
AG+ GR CE + C PC+NG C + G+ C C G++G C+ + C S
Sbjct: 1297 AGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR 1356
Query: 195 CKNEATCLNEIGRYTCICPHNYSGVNCELEIDE--CWSQPCLNGATCQDALGAYFCDCA- 251
C N TC++ TC+C ++G C+ PC N TC+ + F C
Sbjct: 1357 CLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLC 1416
Query: 252 -------------------------PGFLGDHCELN-----------TDECASQPC-LHG 274
P + + CEL + +C + C G
Sbjct: 1417 PAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDG 1476
Query: 275 GLCVDGENRYSCNCTGS-----GFTGTHCETLMPLCWSKPC--------HNNATCEDSVD 321
G C N NCT S F+ HC++ C S C C D
Sbjct: 1477 GDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQ---CNSAGCLFDGFDCQRAEGQCNPLYD 1533
Query: 322 NYTC------HCWPGYTGAQCEIDLNEC 343
Y HC G A+CE D +C
Sbjct: 1534 QYCKDHFSDGHCDQGCNSAECEWDGLDC 1561
Score = 135 bits (340), Expect = 3e-31
Identities = 72/203 (35%), Positives = 94/203 (46%), Gaps = 17/203 (8%)
Query: 1142 VCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHG--NCSDRVAAY 1198
V S C + G C D Y C+CP G+ G+ CE +++EC SNPC G NC RV +
Sbjct: 1232 VSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDF 1291
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN---GYSCLCFGNFTGKFCRQSRLP 1255
HC C G+TG CE I+ C+ C NG TC +N G+ C C F G C
Sbjct: 1292 HCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEND--- 1348
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE--CASDPCVNGGLCQ 1313
+ CG+ L C NGG C C+C FTG C+ +PC N G C+
Sbjct: 1349 ARTCGS----LRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE 1404
Query: 1314 DLLNK--FQCLCDVAFAGERCEV 1334
++CLC F G C +
Sbjct: 1405 PTSESPFYRCLCPAKFNGLLCHI 1427
Score = 120 bits (302), Expect = 7e-27
Identities = 67/195 (34%), Positives = 96/195 (49%), Gaps = 18/195 (9%)
Query: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCS--DR--VAAYHCTC 1202
CL+GG CE + C C + G C+ + + C S PC + G C DR VA Y C+C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSC 89
Query: 1203 EPGYTGVNCEVDIDN-CQSHQCANGATC-ISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG 1260
G++G C +DN C ++ C NG TC + Y C C ++GK C+Q + C
Sbjct: 90 ALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ----ADPCA 145
Query: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNK 1318
+ C NGG C F+ C C P F G C +D++EC P C +GG C + +
Sbjct: 146 SN----PCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS 201
Query: 1319 FQCLCDVAFAGERCE 1333
++C+C G CE
Sbjct: 202 YRCVCRATHTGPNCE 216
Score = 73.2 bits (178), Expect = 2e-12
Identities = 45/158 (28%), Positives = 56/158 (35%), Gaps = 48/158 (30%)
Query: 1140 LNVCNSNPCLHGG--NCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN----CSD 1193
+N C SNPC G NC + +HC C G +G+ CE I+ C PC +G S+
Sbjct: 1268 VNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASN 1327
Query: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG------------------ 1235
+ C C G+ G CE D C S +C NG TCIS
Sbjct: 1328 TARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPA 1387
Query: 1236 ------------------------YSCLCFGNFTGKFC 1249
Y CLC F G C
Sbjct: 1388 SSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 64.7 bits (156), Expect = 6e-10
Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 888 DNSCKSNPCHNGGVCHS-RWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGF 946
DN+C +NPC NGG C ++ C CP SGK+C++ C +PC +G QC P +
Sbjct: 103 DNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASY 162
Query: 947 ECIANAVFNG 956
C F+G
Sbjct: 163 ICHCPPSFHG 172
Score = 63.9 bits (154), Expect = 1e-09
Identities = 28/71 (39%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 891 CKSNPCHNGGVCHSR--WDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
C +PC NGG C ++ FSC CP G+ CE ++ C SPC HGA CQ G+
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
Query: 948 CIANAVFNGQS 958
C A ++G++
Sbjct: 893 CHCQAGYSGRN 903
Score = 60.8 bits (146), Expect = 9e-09
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
+ C NPCHNGG C + F+C CP C EV C +PC HGA C+ L G++
Sbjct: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYK 738
Query: 948 CIANAVFNGQSGQI 961
C + ++G + I
Sbjct: 739 CDCDPGWSGTNCDI 752
Score = 56.2 bits (134), Expect = 2e-07
Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 883 QGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQ 940
+ C D + C+ NPCHNGG C + C C G CEE + C PC +GA C
Sbjct: 902 RNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT 961
Query: 941 PVLQGFECIANAVFNG 956
+ + C A F+G
Sbjct: 962 DCVDSYTCTCPAGFSG 977
Score = 55.5 bits (132), Expect = 4e-07
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
N C S PC +GG C + C+CP +G C+ V WC SPC +G +C +
Sbjct: 1023 NECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082
Query: 948 C 948
C
Sbjct: 1083 C 1083
Score = 55.1 bits (131), Expect = 5e-07
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 12/103 (11%)
Query: 866 PNPTNNAS-----LNPVLVNVTQGCAGD------NSCKSNPCHNGGVCHSRWDDFSCSCP 914
PNP +N +N + G G N C S+PC NG C D ++C+CP
Sbjct: 913 PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 972
Query: 915 ALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVFNG 956
A SG CE C S C +G C + F C+ F G
Sbjct: 973 AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTG 1015
Score = 54.7 bits (130), Expect = 6e-07
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSP--CPHGAQC 939
+ C + C SNPC NGG C + C CP G C ++V CG P C HG C
Sbjct: 136 KSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
Query: 940 QPVLQGFECIANAVFNG 956
+ + C+ A G
Sbjct: 196 HNEVGSYRCVCRATHTG 212
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C S PC +GG C R + + C C T+G CE + C SPC G C + G+E
Sbjct: 605 NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT-CLDKIDGYE 663
Query: 948 CIANAVFNG 956
C + G
Sbjct: 664 CACEPGYTG 672
Score = 52.0 bits (123), Expect = 4e-06
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S+PC + G C + ++F C CP +G C+ +V C +PC +GA+C +
Sbjct: 492 DECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYT 551
Query: 948 CIANAVFNG 956
C+ + G
Sbjct: 552 CVCTEGYTG 560
Score = 51.6 bits (122), Expect = 5e-06
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGF 946
+N C+SNPC NGG C + C+C SG C+ + C +PC + C + G+
Sbjct: 754 NNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY 813
Query: 947 ECIANAVFNGQSGQIL 962
+C + G + +++
Sbjct: 814 KCNCLLPYTGATCEVV 829
Score = 51.6 bits (122), Expect = 5e-06
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
C + C NGG C + F+C CP +G C+ +V C PC HG CQ + C
Sbjct: 987 CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCT 1046
Query: 950 ANAVFNGQSGQIL 962
+ G + Q L
Sbjct: 1047 CPQGYTGPNCQNL 1059
Score = 51.2 bits (121), Expect = 7e-06
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C SNPC N C + +F C C G CE C SPC H +C + F+
Sbjct: 454 NECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513
Query: 948 CIANAVFNG 956
C F G
Sbjct: 514 CECPTGFTG 522
Score = 50.8 bits (120), Expect = 9e-06
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 866 PNPTNNASLNPVLVNVTQGCA------GDN------SCKSNPCHNGGVCHSRWDDFSCSC 913
P+P N +VT CA G N C N C NGG C + ++C C
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
Query: 914 PALTSGKAC-EEVQWCGFSP--CPHGAQCQPVLQGFECIANAVFNGQSGQ 960
P +G+ C E+V C P C +G C G+ C+ NG +G+
Sbjct: 284 PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC---VNGWTGE 330
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL----LNKFQCL 1322
TC NGG C C+C F G C+ D + C S PC N G C + + + C
Sbjct: 30 TCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACS 88
Query: 1323 CDVAFAGERC 1332
C + F+G C
Sbjct: 89 CALGFSGPLC 98
Score = 48.1 bits (113), Expect = 6e-05
Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 5/69 (7%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFS--CSCPALTSGKAC-EEVQWC--GFSPCPHGAQC 939
C +++C SNPC+ G C + + C+CP+ +G AC ++V C G +PC H +C
Sbjct: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
Query: 940 QPVLQGFEC 948
L FEC
Sbjct: 430 INTLGSFEC 438
Score = 48.1 bits (113), Expect = 6e-05
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
C +GG+C + C C A +G CE+ V C SPC +GA C L G+ C A +
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Query: 955 NG 956
+G
Sbjct: 1176 HG 1177
Score = 47.8 bits (112), Expect = 8e-05
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 889 NSCKSNP--CHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQ- 944
N C P C +GG CH+ + C C A +G CE C SPC +G C+P
Sbjct: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV 239
Query: 945 GFECIANAVFNGQS 958
EC F GQ+
Sbjct: 240 THECACLPGFTGQN 253
Score = 47.4 bits (111), Expect = 1e-04
Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ 944
N CK PC NGG C + F C CPA G CE + + CG C +G C +
Sbjct: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPR 1368
Query: 945 GFECIANAVFNGQSGQ 960
C+ F G Q
Sbjct: 1369 SPTCLCLGPFTGPECQ 1384
Score = 46.6 bits (109), Expect = 2e-04
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 894 NPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFEC 948
N C NGG CH+ ++C C +G+ C E + C + C HGA C + F C
Sbjct: 304 NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC 359
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 875 NPVLVNVTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQW 927
N L +G G N C S+PC + G C + D + C+C +G C +
Sbjct: 623 NAYLCFCLKGTTGPNCEINLDDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDE 681
Query: 928 CGFSPCPHGAQCQPVLQGFEC 948
C +PC +G C+ + GF C
Sbjct: 682 CAGNPCHNGGTCEDGINGFTC 702
Score = 45.4 bits (106), Expect = 4e-04
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
+ C +PC NG C +SC C A G C EE+ C PC +G C + ++
Sbjct: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
Query: 948 C 948
C
Sbjct: 1207 C 1207
Score = 45.1 bits (105), Expect = 5e-04
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 15/100 (15%)
Query: 851 CIQDVRLNNQNLEFFPNPTNNASL--------NPVLVNVTQG--CAGD-NSCKSNPCHNG 899
C +DV + PN N N V VN G C+ + + C S C +G
Sbjct: 292 CTEDV----DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHG 347
Query: 900 GVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
CH R F C CP +G C C +PC G+ C
Sbjct: 348 ATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNC 387
Score = 45.1 bits (105), Expect = 5e-04
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFEC 948
S +NPC + G C + F C C +G CE +V C +PC + A C + F+C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQC 476
Query: 949 IANAVFNG 956
I + G
Sbjct: 477 ICMPGYEG 484
Score = 44.7 bits (104), Expect = 6e-04
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 883 QGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQ 940
Q C D N C +PC +G C + + C C A SG+ CE ++ C +PC +G C
Sbjct: 864 QTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCT 923
Query: 941 PVLQGFECIANAVFNG 956
+ C F G
Sbjct: 924 DGINTAFCDCLPGFRG 939
Score = 44.7 bits (104), Expect = 6e-04
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 15/96 (15%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--------EVQWCGFSP-CPHGAQC 939
+ C S+PC NGG C + + CSCP T G CE V SP C + C
Sbjct: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC 1244
Query: 940 QPVLQGFECIANAVFNGQSGQILFRSNGNITRELTN 975
+ G+ C F G+ R G++ L+N
Sbjct: 1245 VDQVGGYSCTCPPGFVGE------RCEGDVNECLSN 1274
Score = 42.4 bits (98), Expect = 0.003
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S PC NG C + ++C C +G CE ++ C PC +G+ C+ + F
Sbjct: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGS-CKDGVATFT 588
Query: 948 CIANAVFNG 956
C+ + G
Sbjct: 589 CLCRPGYTG 597
Score = 40.8 bits (94), Expect = 0.009
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C +PCH G C F+C C +G CE + C PC HG CQ +
Sbjct: 568 DECDPDPCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626
Query: 948 C 948
C
Sbjct: 627 C 627
Score = 40.4 bits (93), Expect = 0.012
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 670 CVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
C + D C S PC + G+C+ SY C C + GP C ++
Sbjct: 138 CQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD 178
Score = 40.4 bits (93), Expect = 0.012
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ + CES PC + G C ++ Y C C + GPNC
Sbjct: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNC 788
Score = 40.4 bits (93), Expect = 0.012
Identities = 16/32 (50%), Positives = 20/32 (62%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C+SQPC G C + SY+C C + Y GPNC
Sbjct: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056
Score = 39.7 bits (91), Expect = 0.021
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE---EVQWCGFSPCPHGAQCQ 940
C D +C S C NGG C S +C C +G C+ G +PC + C+
Sbjct: 1345 CENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE 1404
Query: 941 PVLQG--FECIANAVFNGQSGQILFRSNG 967
P + + C+ A FNG IL S G
Sbjct: 1405 PTSESPFYRCLCPAKFNGLLCHILDYSFG 1433
Score = 39.3 bits (90), Expect = 0.027
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPC-PHGAQ-CQPVLQ 944
D +S C N G C + +SC+CP G+ CE +V C +PC G Q C +
Sbjct: 1230 DPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVN 1289
Query: 945 GFECIANA---------VFNGQSGQILFRSNGNITRELTNITFGF 980
F C A V NG G+ NG +N GF
Sbjct: 1290 DFHCECRAGHTGRRCESVINGCKGKPC--KNGGTCAVASNTARGF 1332
Score = 38.9 bits (89), Expect = 0.035
Identities = 15/34 (44%), Positives = 22/34 (64%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PCQ+ G C++L +Y+C C R +G +C
Sbjct: 1185 DECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
Score = 38.9 bits (89), Expect = 0.035
Identities = 41/163 (25%), Positives = 62/163 (38%), Gaps = 36/163 (22%)
Query: 1146 NPCLHGGNCEDIYSS--YHCSCPLGWSGKHCEL----------------NIDECFSNPCI 1187
NPC + G CE S Y C CP ++G C + I+E P
Sbjct: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPEC 1454
Query: 1188 HGNCSDRVAAYHCTCEP-GYTGVNCEVDID----NC-QSHQC---ANGATCISHTNGYSC 1238
+ ++V + C G+ G +C ++ + NC QS QC + C S N C
Sbjct: 1455 QEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGC 1514
Query: 1239 LCFGNFTGKFCRQSR-----LPSTVCGNEKTNLTCYNGGNCTE 1276
L F G C+++ L C + ++ C G N E
Sbjct: 1515 L----FDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAE 1553
Score = 38.5 bits (88), Expect = 0.046
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ PC+ G+CIN S++C C + Y GP C
Sbjct: 420 ANPCEHAGKCINTLGSFECQCLQGYTGPRC 449
Score = 38.5 bits (88), Expect = 0.046
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC ++G CI+ Y+C+C PY G C
Sbjct: 795 CASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
Score = 37.7 bits (86), Expect = 0.078
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 675 WCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
WC+S PC++ G+C Y+C+C + G C
Sbjct: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYC 1094
Score = 37.4 bits (85), Expect = 0.10
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 628 LNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKDWCESQPCQSRGRC 687
+N + S+P G D KID E +GS N+ D C PC + G C
Sbjct: 640 INLDDCASSPCDSGTCLD-KIDGYECACEPGYTGSMCNINI-----DECAGNPCHNGGTC 693
Query: 688 INLWLSYQCDCHRPYEGPNCLRE 710
+ + C C Y P CL E
Sbjct: 694 EDGINGFTCRCPEGYHDPTCLSE 716
Score = 36.2 bits (82), Expect = 0.23
Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 676 CESQP--CQSRGRCINLWLSYQCDCHRPYEGPNCLREYV 712
C +P C+ G C N SY+C C + GPNC R YV
Sbjct: 182 CGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYV 220
Score = 35.8 bits (81), Expect = 0.30
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
V D C S PC GRC++ +QC+C + G C
Sbjct: 489 VNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLC 525
Score = 35.0 bits (79), Expect = 0.51
Identities = 14/37 (37%), Positives = 16/37 (43%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
D C PCQ+ C + Y C C Y G NC E
Sbjct: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
Score = 34.7 bits (78), Expect = 0.66
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C SQPC+ G C + +Y C C + GPNC
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Score = 33.9 bits (76), Expect = 1.1
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PCQ+ C++ +QC C YEG +C
Sbjct: 456 CVSNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
Score = 32.7 bits (73), Expect = 2.5
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 1304 DPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
+ C+NGG C+ C+C AF G RC+
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRCQ 58
Score = 32.7 bits (73), Expect = 2.5
Identities = 14/47 (29%), Positives = 20/47 (42%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPV 942
C NGG C + +C C G C++ C +PC + C V
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVV 77
Score = 32.7 bits (73), Expect = 2.5
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 14/90 (15%)
Query: 631 YNMPSTPSFVGCLQDIKID-------WNHITLENISSGSSLNVKAG-----CVRK-DWCE 677
Y P + G + +I ID N T E+ +G + G C+ + + C
Sbjct: 662 YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN 721
Query: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
S PC G C + Y+CDC + G NC
Sbjct: 722 SNPCV-HGACRDSLNGYKCDCDPGWSGTNC 750
Score = 32.3 bits (72), Expect = 3.3
Identities = 12/34 (35%), Positives = 19/34 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PC++ +C++ +Y C C Y G +C
Sbjct: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHC 563
Score = 32.0 bits (71), Expect = 4.3
Identities = 12/32 (37%), Positives = 14/32 (43%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC+ C N Y+C C Y G NC
Sbjct: 873 CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC 904
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 375 bits (964), Expect = e-103
Identities = 190/520 (36%), Positives = 253/520 (48%), Gaps = 88/520 (16%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C++N C SC STC D C C + L ++ D C SNPC A C
Sbjct: 335 CSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGL---LCHLDDACISNPCHKGALCD 391
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCG---KNSCQHGGICHQDPIYPVCICPAGYAGR 143
P ++C CP GY G C + C N C+H G C C C GYAG
Sbjct: 392 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP 451
Query: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
CE+D +EC S PCQN A C D I G++C C+PG++G HC+LE++EC S+PC N C++
Sbjct: 452 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD 511
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGA-------------------------- 237
++ R+ C+CP ++G C+++ID+C S PCLNGA
Sbjct: 512 KVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
Query: 238 -----------TCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSC 286
CQD + +Y C C PG++G C DEC S PCL+ G C+D N Y C
Sbjct: 572 DNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQC 631
Query: 287 NCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSN 346
NC G +G +CE C S PC + C D ++ Y+C C PG+TG +C ID++EC SN
Sbjct: 632 NCQ-PGTSGVNCEINFDDCASNPC-IHGICMDGINRYSCVCSPGFTGQRCNIDIDECASN 689
Query: 347 PCQSNGECVE-------------------------LSSEKQYGRITGLPSSFSYHEASGY 381
PC+ C+ LS+ +G TG SGY
Sbjct: 690 PCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTG--------GLSGY 741
Query: 382 VCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDI 441
C+C G+ GI+CE D NEC SNPCQNGGTC+NL Y C C + + G +C
Sbjct: 742 KCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTC------KKGFKGYNCQVN 795
Query: 442 LLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
+ C CLN GTC D G++C C YTG C+
Sbjct: 796 IDECASNPCLNQGTCF----DDISGYTCHCVLPYTGKNCQ 831
Score = 370 bits (949), Expect = e-102
Identities = 186/496 (37%), Positives = 253/496 (51%), Gaps = 77/496 (15%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C N C SN C + C D C CS + C+ D C SNPC+ ATC+
Sbjct: 642 CEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTG--QRCNIDIDECASNPCRKGATCI 698
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
N G F C CP G C + + C N C HG Y C+C AG+ G CE
Sbjct: 699 N--GVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYK-CLCDAGWVGINCE 755
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
+D +EC S+PCQNG C + ++GY C C G++G +C + +DECAS+PC N+ TC ++I
Sbjct: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDIS 815
Query: 207 RYTCICPHNYSGVNCE----------------------------------------LEID 226
YTC C Y+G NC+ ++ID
Sbjct: 816 GYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDID 875
Query: 227 ECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSC 286
EC S+PC+N C + G+Y C+C PGF G CE + D+C + PC +GG C+DG N +SC
Sbjct: 876 ECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSC 935
Query: 287 NCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSN 346
C GFTG C+T M C S+PC N TC D V++YTC C G+ G CE ++NEC +
Sbjct: 936 LCL-PGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTES 994
Query: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPC 406
C + G CV+ G+ +SFS C+C GFTG C ++NECSS+PC
Sbjct: 995 SCFNGGTCVD-----------GI-NSFS--------CLCPVGFTGSFCLHEINECSSHPC 1034
Query: 407 QNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHG 466
N GTC + G Y C CP Y G++C ++ C+ C N GTC+ + Q
Sbjct: 1035 LNEGTCVDGLGTYRCSCPLG------YTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ-- 1086
Query: 467 FSCLCPSGYTGSLCEI 482
CLCPSG+ G+ C++
Sbjct: 1087 --CLCPSGWAGAYCDV 1100
Score = 366 bits (940), Expect = e-101
Identities = 173/465 (37%), Positives = 234/465 (50%), Gaps = 43/465 (9%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C N C SN C N TC D C C K+C + PC NPC+ +A C
Sbjct: 792 CQVNIDECASNPCLNQGTCFDDISGYTCHC--VLPYTGKNCQTVLAPCSPNPCENAAVCK 849
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+P S+ C C PG+ G C I C C + G+CH +C CP G++G CE
Sbjct: 850 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
D D+C ++PCQNG C DG++ +SC C+PG+ G C +++EC S+PCKN TC + +
Sbjct: 910 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN 969
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
YTC C + GV+CE I+EC C NG TC D + ++ C C GF G C +EC
Sbjct: 970 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC 1029
Query: 267 ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
+S PCL+ G CVDG Y C+C G+TG +C+TL+ LC PC N TC C
Sbjct: 1030 SSHPCLNEGTCVDGLGTYRCSCP-LGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCL 1088
Query: 327 CWPGYTGAQCEIDLNECN----------SNPCQSNGECVELSSEKQYGRITGLPSSFSYH 376
C G+ GA C++ C+ + CQ +G C+ +
Sbjct: 1089 CPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI--------------------N 1128
Query: 377 EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGR 436
+ + C C G+TG +CEE ++EC+SNPCQ+G TC + G Y C C Y G
Sbjct: 1129 AGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECV------PGYQGV 1182
Query: 437 DCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
+C + C +Q C N GTCI D + F C CP G G LCE
Sbjct: 1183 NCEYEVDECQNQPCQNGGTCI----DLVNHFKCSCPPGTRGLLCE 1223
Score = 352 bits (904), Expect = 1e-96
Identities = 179/520 (34%), Positives = 256/520 (49%), Gaps = 76/520 (14%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQ 80
+ S C +N C ++ CQN C D +C C + C D C P CQ
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTG--QFCTEDVDECLLQPNACQ 310
Query: 81 GSATCVN------------------------------TPGE------RSFLCKCPPGYSG 104
TC N TPG SF C CP G +G
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 105 TICETTIGSCGKNSCQHGGICHQDPI--YPVCICPAGYAGRFCEIDHDECA---SSPCQN 159
+C +C N C G +C +P+ +C CP GY G C D DECA S+PC++
Sbjct: 371 LLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH 429
Query: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGV 219
C + + C C+ GY G C+++++EC SDPC+N+ATCL++IG +TC+C + GV
Sbjct: 430 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV 489
Query: 220 NCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVD 279
+CELEI+EC S PC+N C D + + C C PGF G C+++ D+C+S PCL+G C+D
Sbjct: 490 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID 549
Query: 280 GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339
N Y C C +GFTG CE + C PCH + C+D +D+YTC C PGY GA C
Sbjct: 550 HPNGYECQC-ATGFTGVLCEENIDNCDPDPCH-HGQCQDGIDSYTCICNPGYMGAICSDQ 607
Query: 340 LNECNSNPCQSNGECVELSSEKQYG---RITGLPSSFSYHEASG--------------YV 382
++EC S+PC ++G C++L + Q +G+ ++ + + Y
Sbjct: 608 IDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYS 667
Query: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDIL 442
C+C PGFTG C D++EC+SNPC+ G TC N + C CP + Y
Sbjct: 668 CVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYS-------- 719
Query: 443 LGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
+CL+N + G G+ CLC +G+ G CE+
Sbjct: 720 ---QVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEV 756
Score = 343 bits (879), Expect = 9e-94
Identities = 166/462 (35%), Positives = 233/462 (50%), Gaps = 44/462 (9%)
Query: 27 CNKNNTRC-LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC 85
C + C + CQ+ TC + C C + CD++ PC +PC TC
Sbjct: 179 CETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTG--QYCDSLYVPCAPSPCVNGGTC 236
Query: 86 VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC 145
T G+ +F C C PG+ G+ CE I C + CQ+GG+C C CP + G+FC
Sbjct: 237 RQT-GDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
Query: 146 EIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
D DEC P CQNG C + GY C CV G+ G C +D+CA C +TC++
Sbjct: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC--QDALGAYFCDCAPGFLGDHCEL 261
+ ++C+CP +G+ C L+ D C S PC GA C G Y C C G+ G C
Sbjct: 356 RVASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTE 414
Query: 262 NTDECA---SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCED 318
+ DECA S PC H G CV+ + + C C G+ G CE + C S PC N+ATC D
Sbjct: 415 DVDECAMANSNPCEHAGKCVNTDGAFHCECL-KGYAGPRCEMDINECHSDPCQNDATCLD 473
Query: 319 SVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 378
+ +TC C PG+ G CE+++NEC SNPC +NG+CV+ +
Sbjct: 474 KIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD--------------------KV 513
Query: 379 SGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDC 438
+ + C+C PGFTG C+ D+++CSS PC NG C + P Y C C T + G C
Sbjct: 514 NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC------ATGFTGVLC 567
Query: 439 SDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
+ + C C ++G C QDG ++C+C GY G++C
Sbjct: 568 EENIDNCDPDPC-HHGQC----QDGIDSYTCICNPGYMGAIC 604
Score = 334 bits (857), Expect = 3e-91
Identities = 179/538 (33%), Positives = 243/538 (45%), Gaps = 110/538 (20%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C ++ CL+N CQN +C D C C DK C + C S PC+ TC
Sbjct: 908 CEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTG-DK-CQTDMNECLSEPCKNGGTCS 965
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ S+ CKC G+ G CE I C ++SC +GG C C+CP G+ G FC
Sbjct: 966 DYVN--SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
+ +EC+S PC N C DG+ Y C C GY G++C V+ C+ PCKN+ TC+ +
Sbjct: 1024 HEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKA 1083
Query: 207 RYTCICPHN------------------------------------------------YSG 218
C+CP Y+G
Sbjct: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Query: 219 VNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCV 278
CE ++DEC S PC +GATC D +G Y C+C PG+ G +CE DEC +QPC +GG C+
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCI 1203
Query: 279 DGENRYSCNCTGSGFTGTHCETLMPLCWSKP-CHNNATCEDSVDNYTCHCWPGYTGAQCE 337
D N + C+C G G CE + C P C N C D + Y+C C PG+ G +CE
Sbjct: 1204 DLVNHFKCSCP-PGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
Query: 338 IDLNECNSNPCQSNG--ECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE 395
D+NEC SNPC S G +C++L+++ Y+C+C+ FTG HCE
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTND--------------------YLCVCRSAFTGRHCE 1302
Query: 396 EDVNECSSNPCQNGGTC---ENLPGNYTCHCP-------------------FDNLSRTFY 433
V+ C PC NGGTC N+P + C CP + T
Sbjct: 1303 TFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTAS 1362
Query: 434 GGR-------DCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIAT 484
G R DC GC C + G+C P Q +SC C ++GS CE+ T
Sbjct: 1363 GPRCFCPSPRDCES---GCASSPCQHGGSCHPQRQPPY--YSCQCAPPFSGSRCELYT 1415
Score = 311 bits (797), Expect = 3e-84
Identities = 164/429 (38%), Positives = 214/429 (49%), Gaps = 54/429 (12%)
Query: 15 SFSLL--IYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKD 72
SFS L + SFC C S+ C N TC D CSC K+C + +
Sbjct: 1008 SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP--LGYTGKNCQTLVN 1065
Query: 73 PCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCG----------KNSCQHG 122
C +PC+ TCV E C CP G++G C+ SC ++ CQH
Sbjct: 1066 LCSRSPCKNKGTCVQKKAESQ--CLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHS 1123
Query: 123 GICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRH 182
G+C C CP GY G +CE DECAS+PCQ+GA C D I GY C CVPGYQG +
Sbjct: 1124 GVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVN 1183
Query: 183 CDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQP-CLNGATCQD 241
C+ EVDEC + PC+N TC++ + + C CP G+ CE ID+C P CLNG C D
Sbjct: 1184 CEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMD 1243
Query: 242 ALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL--CVDGENRYSCNCTGSGFTGTHCE 299
+G Y C C PGF G+ CE + +EC S PC G C+ N Y C C S FTG HCE
Sbjct: 1244 RIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCR-SAFTGRHCE 1302
Query: 300 TLMPLCWSKPCHNNATC---EDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVE 356
T + +C PC N TC + D + C C PG++GA+C+ + C C+ +CV
Sbjct: 1303 TFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ---SSCGQVKCRKGEQCV- 1358
Query: 357 LSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTC--EN 414
H ASG C C + CE + C+S+PCQ+GG+C +
Sbjct: 1359 -------------------HTASGPRCFCP---SPRDCE---SGCASSPCQHGGSCHPQR 1393
Query: 415 LPGNYTCHC 423
P Y+C C
Sbjct: 1394 QPPYYSCQC 1402
Score = 269 bits (688), Expect = 1e-71
Identities = 155/475 (32%), Positives = 221/475 (46%), Gaps = 47/475 (9%)
Query: 39 CQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCK 97
C N C + C C + L + C + +DPC N CQ TCV C+
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPE--GFLGEYCQH-RDPCEKNRCQNGGTCVAQAMLGKATCR 91
Query: 98 CPPGYSGTICE-TTIGSCG-KNSCQHGGICHQ--DPIYPVCICPAGYAGRFCEIDHDECA 153
C G++G C+ +T C C +GG CH Y C C G+ G+ C+ D C
Sbjct: 92 CASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYE-CTCQVGFTGKECQWT-DACL 149
Query: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC-ASDPCKNEATCLNEIGRYTCIC 212
S PC NG+ C + +SC C+ G+ G+ C+ +V+EC C++ TCLN G Y C C
Sbjct: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQC 209
Query: 213 PHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF-CDCAPGFLGDHCELNTDECASQPC 271
P ++G C+ C PC+NG TC+ F C+C PGF G CE N D+C + C
Sbjct: 210 PQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRC 269
Query: 272 LHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP--CHNNATCEDSVDNYTCHCWP 329
+GG+CVDG N Y+C C +TG C + C +P C N TC + Y C C
Sbjct: 270 QNGGVCVDGVNTYNCRCPPQ-WTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVN 328
Query: 330 GYTGAQCEIDLNECNSNPCQSNGECVE-------LSSEKQYGRITGLPS---SFSYHEAS 379
G++G C ++++C C C++ + E + G + L S H+ +
Sbjct: 329 GWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA 388
Query: 380 ---------GYVCICQPGFTGIHCEEDVNEC---SSNPCQNGGTCENLPGNYTCHCPFDN 427
Y+C C G+ G C EDV+EC +SNPC++ G C N G + C C
Sbjct: 389 LCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCEC---- 444
Query: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Y G C + C C N+ TC+ D GF+CLC G+ G CE+
Sbjct: 445 --LKGYAGPRCEMDINECHSDPCQNDATCL----DKIGGFTCLCMPGFKGVHCEL 493
Score = 191 bits (485), Expect = 4e-48
Identities = 85/198 (42%), Positives = 116/198 (58%), Gaps = 8/198 (4%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY 1198
Q++ C S+PCL+ G C D+ + Y C+C G SG +CE+N D+C SNPCIHG C D + Y
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRY 666
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C PG+TG C +DID C S+ C GATCI+ NG+ C+C C
Sbjct: 667 SCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ------ 720
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
NE + C + GNCT + KC+C G+ G CE D +EC S+PC NGG C +L+N
Sbjct: 721 -VNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 1319 FQCLCDVAFAGERCEVDL 1336
++C C F G C+V++
Sbjct: 779 YRCTCKKGFKGYNCQVNI 796
Score = 187 bits (476), Expect = 5e-47
Identities = 86/230 (37%), Positives = 122/230 (53%), Gaps = 32/230 (13%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVA 1196
+ +N C+S+PC + C D + C C G+ G HCEL I+EC SNPC++ G C D+V
Sbjct: 455 MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVN 514
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR------ 1250
+ C C PG+TG C++DID+C S C NGA CI H NGY C C FTG C
Sbjct: 515 RFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNC 574
Query: 1251 ----------QSRLPSTVC--------------GNEKTNLTCYNGGNCTEFQTELKCMCR 1286
Q + S C +E + C N G C + +C C+
Sbjct: 575 DPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQ 634
Query: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
PG +G CE + D+CAS+PC++ G+C D +N++ C+C F G+RC +D+
Sbjct: 635 PGTSGVNCEINFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDI 683
Score = 186 bits (473), Expect = 1e-46
Identities = 78/197 (39%), Positives = 113/197 (57%), Gaps = 8/197 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
+ ++ C S PC++ G C + SY C CP G+SG CE +ID+C +NPC +G +C D V
Sbjct: 872 IDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN 931
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
+ C C PG+TG C+ D++ C S C NG TC + N Y+C C F G C +
Sbjct: 932 TFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI--- 988
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
NE T +C+NGG C + C+C GFTG +C +I+EC+S PC+N G C D L
Sbjct: 989 ----NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044
Query: 1317 NKFQCLCDVAFAGERCE 1333
++C C + + G+ C+
Sbjct: 1045 GTYRCSCPLGYTGKNCQ 1061
Score = 179 bits (453), Expect = 2e-44
Identities = 82/189 (43%), Positives = 105/189 (55%), Gaps = 9/189 (4%)
Query: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPGY 1206
C H G C + ++++C CPLG++G +CE +DEC SNPC HG CSD + Y C C PGY
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
Query: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
GVNCE ++D CQ+ C NG TCI N + C C G C ++ + G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEEN-IDDCARGPH---- 1234
Query: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL--CQDLLNKFQCLCD 1324
C NGG C + C C PGF GE CE DI+EC S+PC + G C L N + C+C
Sbjct: 1235 -CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCR 1293
Query: 1325 VAFAGERCE 1333
AF G CE
Sbjct: 1294 SAFTGRHCE 1302
Score = 178 bits (451), Expect = 4e-44
Identities = 105/295 (35%), Positives = 140/295 (47%), Gaps = 39/295 (13%)
Query: 193 DPCKNEATCLN-EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC--QDALGAYFCD 249
+PC NE C+ G C CP + G C+ D C C NG TC Q LG C
Sbjct: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCR 91
Query: 250 CAPGFLGDHCELNTDE--CASQPCLHGGLC-VDGENRYSCNCTGSGFTGTHCETLMPLCW 306
CA GF G+ C+ +T S+PCL+GG C + + Y C C GFTG C+ C
Sbjct: 92 CASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQ-VGFTGKECQWT-DACL 149
Query: 307 SKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGR 365
S PC N +TC + ++C C G+TG +CE D+NEC+ CQ G C+
Sbjct: 150 SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL---------- 199
Query: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPF 425
LP S Y C C GFTG +C+ C+ +PC NGGTC G++T C
Sbjct: 200 --NLPGS--------YQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQ-TGDFTFEC-- 246
Query: 426 DNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
N F G C + C + +C N G C+ DG + ++C CP +TG C
Sbjct: 247 -NCLPGFEGS-TCERNIDDCPNHRCQNGGVCV----DGVNTYNCRCPPQWTGQFC 295
Score = 174 bits (441), Expect = 5e-43
Identities = 81/202 (40%), Positives = 107/202 (52%), Gaps = 13/202 (6%)
Query: 1141 NVCNSNPCLHGGNCED--IYSSYHCSCPLGWSGKHCELNIDECF---SNPCIH-GNCSDR 1194
+ C SNPC G C+ + Y C+CP G+ G C ++DEC SNPC H G C +
Sbjct: 377 DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT 436
Query: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRL 1254
A+HC C GY G CE+DI+ C S C N ATC+ G++CLC F G C
Sbjct: 437 DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI- 495
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
NE + C N G C + +C+C PGFTG C+ DID+C+S PC+NG C D
Sbjct: 496 ------NECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID 549
Query: 1315 LLNKFQCLCDVAFAGERCEVDL 1336
N ++C C F G CE ++
Sbjct: 550 HPNGYECQCATGFTGVLCEENI 571
Score = 173 bits (438), Expect = 1e-42
Identities = 82/239 (34%), Positives = 120/239 (50%), Gaps = 34/239 (14%)
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYH 1199
N C SNPC +GG C+++ + Y C+C G+ G +C++NIDEC SNPC++ G C D ++ Y
Sbjct: 759 NECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN--GYSCLCFGNFTGKFCR------- 1250
C C YTG NC+ + C + C N A C N Y+CLC + G+ C
Sbjct: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECI 878
Query: 1251 -QSRLPSTVCGNEKTNLTC-----------------------YNGGNCTEFQTELKCMCR 1286
+ + +C N + + C NGG+C + C+C
Sbjct: 879 SKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCL 938
Query: 1287 PGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLISDIF 1345
PGFTG+ C+ D++EC S+PC NGG C D +N + C C F G CE ++ + S F
Sbjct: 939 PGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCF 997
Score = 170 bits (431), Expect = 8e-42
Identities = 88/239 (36%), Positives = 116/239 (48%), Gaps = 39/239 (16%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
+ ++ C SNPC G C + + + C CP G C ++EC SNPCIHGNC+ ++
Sbjct: 681 IDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG 740
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQS--RLP 1255
Y C C+ G+ G+NCEVD + C S+ C NG TC + NGY C C F G C+ +
Sbjct: 741 YKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA 800
Query: 1256 STVCGNEKT------NLTC-----YNGGNCTEFQTEL----------------------- 1281
S C N+ T TC Y G NC QT L
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPYTGKNC---QTVLAPCSPNPCENAAVCKESPNFESY 857
Query: 1282 KCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
C+C PG+ G+ C DIDEC S PC+N GLC + + C C F+G CE D+ D L
Sbjct: 858 TCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCL 916
Score = 163 bits (413), Expect = 9e-40
Identities = 97/313 (30%), Positives = 137/313 (43%), Gaps = 59/313 (18%)
Query: 1137 CL-QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDR 1194
CL ++N C+S+PCL+ G C D +Y CSCPLG++GK+C+ ++ C +PC + G C +
Sbjct: 1022 CLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQK 1081
Query: 1195 VA------------------------------------------------AYHCTCEPGY 1206
A ++C C GY
Sbjct: 1082 KAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY 1141
Query: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
TG CE +D C S+ C +GATC GY C C + G C +E N
Sbjct: 1142 TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEV-------DECQNQ 1194
Query: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP-CVNGGLCQDLLNKFQCLCDV 1325
C NGG C + KC C PG G CE++ID+CA P C+NGG C D + + C C
Sbjct: 1195 PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLP 1254
Query: 1326 AFAGERCEVDLADDLISDIFTTIGSVTVALLLILLLAIVASVVTSNKRATQGTYSPSRQE 1385
FAGERCE D+ ++ +S+ ++ GS+ L L + S T T P
Sbjct: 1255 GFAGERCEGDI-NECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC 1313
Query: 1386 KEGSRVEMWNLMP 1398
G + + MP
Sbjct: 1314 LNGGTCAVASNMP 1326
Score = 162 bits (411), Expect = 2e-39
Identities = 74/186 (39%), Positives = 99/186 (53%), Gaps = 8/186 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
+ ++ C+S PCL+G C D + Y C C G++G CE NID C +PC HG C D + +
Sbjct: 531 IDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDS 590
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Y C C PGY G C ID C S C N CI NGY C C +G C
Sbjct: 591 YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCE------- 643
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
+ ++ + C + G C + C+C PGFTG+ C DIDECAS+PC G C + +N
Sbjct: 644 INFDDCASNPCIH-GICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
Query: 1318 KFQCLC 1323
F+C+C
Sbjct: 703 GFRCIC 708
Score = 151 bits (381), Expect = 5e-36
Identities = 72/201 (35%), Positives = 107/201 (53%), Gaps = 12/201 (5%)
Query: 1145 SNPCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA-AYHCTC 1202
S PCL+GG C + +Y C+C +G++GK C+ D C S+PC +G+ VA + C C
Sbjct: 112 SRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKC 170
Query: 1203 EPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
G+TG CE D++ C C +G TC++ Y C C FTG++C +P
Sbjct: 171 LTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPS-- 228
Query: 1262 EKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQ 1320
C NGG C + +C C PGF G CE++ID+C + C NGG+C D +N +
Sbjct: 229 -----PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYN 283
Query: 1321 CLCDVAFAGERCEVDLADDLI 1341
C C + G+ C D+ + L+
Sbjct: 284 CRCPPQWTGQFCTEDVDECLL 304
Score = 151 bits (381), Expect = 5e-36
Identities = 66/190 (34%), Positives = 99/190 (52%), Gaps = 7/190 (3%)
Query: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA--AYHCTCEPG 1205
C HGG C ++ SY C CP G++G++C+ C +PC++G + + C C PG
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG 251
Query: 1206 YTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265
+ G CE +ID+C +H+C NG C+ N Y+C C +TG+FC + + N
Sbjct: 252 FEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPN---- 307
Query: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDV 1325
C NGG C C+C G++G+ C ++ID+CA C G C D + F C+C
Sbjct: 308 -ACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPE 366
Query: 1326 AFAGERCEVD 1335
AG C +D
Sbjct: 367 GKAGLLCHLD 376
Score = 143 bits (360), Expect = 1e-33
Identities = 73/209 (34%), Positives = 105/209 (50%), Gaps = 14/209 (6%)
Query: 1137 CLQLNVCNSNPCLHGGNC--EDIYSSYHCSCPLGWSGKHCELNIDE-CF-SNPCIHGNCS 1192
C + C N C +GG C + + C C G++G+ C+ + CF S PC++G
Sbjct: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
Query: 1193 DRVA--AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
++ Y CTC+ G+TG C+ D C SH CANG+TC + N +SC C FTG+ C
Sbjct: 122 HMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
Query: 1251 QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGG 1310
+ G+ C +GG C +C C GFTG++C+ CA PCVNGG
Sbjct: 181 TDVNECDIPGH------CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGG 234
Query: 1311 LCQDLLN-KFQCLCDVAFAGERCEVDLAD 1338
C+ + F+C C F G CE ++ D
Sbjct: 235 TCRQTGDFTFECNCLPGFEGSTCERNIDD 263
Score = 142 bits (358), Expect = 2e-33
Identities = 79/234 (33%), Positives = 108/234 (46%), Gaps = 45/234 (19%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-CIH-GNCSDRVA 1196
+++ C + PC +GG C D+ + + CSCP G G CE NID+C P C++ G C DR+
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIG 1246
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT--CISHTNGYSCLCFGNFTGKFCRQSRL 1254
Y C C PG+ G CE DI+ C S+ C++ + CI TN Y C+C FTG+ C
Sbjct: 1247 GYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-- 1304
Query: 1255 PSTVCGNEKTNLTCYNGGNC---TEFQTELKCMCRPGFTGEWCEKDIDE----------- 1300
VC + C NGG C + C C PGF+G C+ +
Sbjct: 1305 -VDVC----PQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVH 1359
Query: 1301 ------------------CASDPCVNGGLC--QDLLNKFQCLCDVAFAGERCEV 1334
CAS PC +GG C Q + C C F+G RCE+
Sbjct: 1360 TASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413
Score = 139 bits (351), Expect = 1e-32
Identities = 76/232 (32%), Positives = 106/232 (45%), Gaps = 38/232 (16%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP--CIH-GNCSDRVAAYH 1199
C ++ C +GG C D ++Y+C CP W+G+ C ++DEC P C + G C++R Y
Sbjct: 264 CPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYG 323
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKF----------- 1248
C C G++G +C +ID+C C G+TCI +SC+C G
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 1249 CRQSRLPSTVCGNEKTNLTC---YNGGNCTEFQTE---------------------LKCM 1284
C + L T N + TC Y G +CTE E C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
Query: 1285 CRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
C G+ G CE DI+EC SDPC N C D + F CLC F G CE+++
Sbjct: 444 CLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI 495
Score = 99.4 bits (246), Expect = 2e-20
Identities = 56/161 (34%), Positives = 79/161 (49%), Gaps = 20/161 (12%)
Query: 1185 PCIH-GNCSDRVAAYH-----CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHT--NGY 1236
PC++ G C YH C C G+ G C+ D C+ ++C NG TC++
Sbjct: 34 PCVNEGMC----VTYHNGTGYCKCPEGFLGEYCQ-HRDPCEKNRCQNGGTCVAQAMLGKA 88
Query: 1237 SCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE-LKCMCRPGFTGEWCE 1295
+C C FTG+ C+ S S C + C NGG C + +C C+ GFTG+ C+
Sbjct: 89 TCRCASGFTGEDCQYS--TSHPC---FVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
Query: 1296 KDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
D C S PC NG C + N+F C C F G++CE D+
Sbjct: 144 W-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDV 183
Score = 75.5 bits (184), Expect = 3e-13
Identities = 57/231 (24%), Positives = 84/231 (36%), Gaps = 49/231 (21%)
Query: 1140 LNVCNSNPCLHGGN--CEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN----CSD 1193
+N C SNPC G+ C + + Y C C ++G+HCE +D C PC++G S+
Sbjct: 1265 INECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASN 1324
Query: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG------------------ 1235
+ C C PG++G C+ +C +C G C+ +G
Sbjct: 1325 MPDGFICRCPPGFSGARCQ---SSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASS 1381
Query: 1236 ----------------YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN---GGNCTE 1276
YSC C F+G C P + + C + G C E
Sbjct: 1382 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDE 1441
Query: 1277 FQTELKCMCRPGFTGEWCEKDIDECASD-PCVN--GGLCQDLLNKFQCLCD 1324
C G E C+S PC + C +L N +CL D
Sbjct: 1442 ACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFD 1492
Score = 60.1 bits (144), Expect = 1e-08
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 14/109 (12%)
Query: 866 PNPTNNASL---NPVLVNVTQGCAGD----------NSCKSNPCHNGGVCHSRWDDFSCS 912
PNP NA++ +P + T CA + C S PC N G+CH+ + C
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCE 898
Query: 913 CPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQ 960
CP SG CEE + C +PC +G C + F C+ F G Q
Sbjct: 899 CPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQ 947
Score = 58.5 bits (140), Expect = 4e-08
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C+SNPC N G C + + F C CP +G C+ ++ C +PC +GA+C G+E
Sbjct: 496 NECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555
Query: 948 CIANAVFNG 956
C F G
Sbjct: 556 CQCATGFTG 564
Score = 58.2 bits (139), Expect = 6e-08
Identities = 32/89 (35%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSP-CPHGAQCQPVLQGF 946
+ C++ PC NGG C + F CSCP T G CEE + C P C +G QC + G+
Sbjct: 1189 DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGY 1248
Query: 947 ECIANAVFNGQSGQILFRSNGNITRELTN 975
C F G+ R G+I L+N
Sbjct: 1249 SCRCLPGFAGE------RCEGDINECLSN 1271
Score = 54.3 bits (129), Expect = 8e-07
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSC-PALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFE 947
+ C +NPC NGG C + FSC C P T K ++ C PC +G C + +
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
Query: 948 CIANAVFNG 956
C A F+G
Sbjct: 973 CKCQAGFDG 981
Score = 53.5 bits (127), Expect = 1e-06
Identities = 27/67 (40%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 893 SNPCHNGGVCH--SRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIA 950
S PC NGG CH SR D + C+C +GK C+ C PC +G+ C V F C
Sbjct: 112 SRPCLNGGTCHMLSR-DTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 951 NAVFNGQ 957
F GQ
Sbjct: 171 LTGFTGQ 177
Score = 52.4 bits (124), Expect = 3e-06
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
+ C S PC NG C + + C C +G CEE + C PC HG QCQ + +
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDSYT 592
Query: 948 CIANAVFNG 956
CI N + G
Sbjct: 593 CICNPGYMG 601
Score = 52.4 bits (124), Expect = 3e-06
Identities = 24/69 (34%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C S PC NGG C + ++C C A G CE + C S C +G C + F
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 948 CIANAVFNG 956
C+ F G
Sbjct: 1011 CLCPVGFTG 1019
Score = 52.0 bits (123), Expect = 4e-06
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C S+PC N C + F+C C G CE E+ C +PC + QC + F+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517
Query: 948 CIANAVFNGQSGQI 961
C+ F G QI
Sbjct: 518 CLCPPGFTGPVCQI 531
Score = 51.2 bits (121), Expect = 7e-06
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 9/103 (8%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGF-SPCPHGAQCQPV 942
C ++C S+PC NG C + + FSC C +G+ CE +V C C HG C +
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
Query: 943 LQGFECIANAVFNGQSGQILFRS-------NGNITRELTNITF 978
++C F GQ L+ NG R+ + TF
Sbjct: 202 PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Score = 50.4 bits (119), Expect = 1e-05
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C SNPC NGG C + + + C+C G C+ + C +PC + C + G+
Sbjct: 759 NECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818
Query: 948 CIANAVFNGQSGQ 960
C + G++ Q
Sbjct: 819 CHCVLPYTGKNCQ 831
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
N C + C NGG C + FSC CP +G C E+ C PC + C L +
Sbjct: 989 NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYR 1048
Query: 948 CIANAVFNGQSGQIL 962
C + G++ Q L
Sbjct: 1049 CSCPLGYTGKNCQTL 1063
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S+PC N G C + + C+C TSG CE C +PC HG C + +
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGI-CMDGINRYS 667
Query: 948 CIANAVFNGQ 957
C+ + F GQ
Sbjct: 668 CVCSPGFTGQ 677
Score = 48.9 bits (115), Expect = 3e-05
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
+ C SNPC G C + + F C CP +C +V C +PC HG C L G++
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYK 742
Query: 948 CIANAVFNG 956
C+ +A + G
Sbjct: 743 CLCDAGWVG 751
Score = 48.5 bits (114), Expect = 4e-05
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFEC 948
C + GVC + + C CP +G CEE + C +PC HGA C + G+ C
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC 1173
Score = 48.1 bits (113), Expect = 6e-05
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 14/109 (12%)
Query: 863 EFFPNPTNNASLNPVLVN-----VTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSC 911
E NP N LVN +G G N C SNPC N G C ++C
Sbjct: 760 ECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC 819
Query: 912 SCPALTSGKACEEV-QWCGFSPCPHGAQCQ--PVLQGFECIANAVFNGQ 957
C +GK C+ V C +PC + A C+ P + + C+ + GQ
Sbjct: 820 HCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ 868
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRW--DDFSCSCPALTSGKAC-EEVQWCGFS---PCPHGAQ 938
C D++C SNPCH G +C + + C+CP G C E+V C + PC H +
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGK 432
Query: 939 CQPVLQGFEC 948
C F C
Sbjct: 433 CVNTDGAFHC 442
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C SNPC +G C + C C A G CE + C +PC +G C ++ G+
Sbjct: 722 NECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
Query: 948 CIANAVFNGQSGQI 961
C F G + Q+
Sbjct: 781 CTCKKGFKGYNCQV 794
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
N C S+PC N G C + CSCP +GK C+ V C SPC + C +
Sbjct: 1027 NECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086
Query: 948 CIANAVFNG 956
C+ + + G
Sbjct: 1087 CLCPSGWAG 1095
Score = 47.0 bits (110), Expect = 1e-04
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 6/74 (8%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSP--CPHGAQCQPVLQG 945
+ C ++ C NGGVC + ++C CP +G+ C E+V C P C +G C G
Sbjct: 262 DDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 946 FECIANAVFNGQSG 959
+ C+ NG SG
Sbjct: 322 YGCVC---VNGWSG 332
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 874 LNPVLVNVTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQ 926
+N N G +G N C SNPC +G +C + +SC C +G+ C ++
Sbjct: 626 VNGYQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDID 684
Query: 927 WCGFSPCPHGAQCQPVLQGFECI 949
C +PC GA C + GF CI
Sbjct: 685 ECASNPCRKGATCINGVNGFRCI 707
Score = 46.6 bits (109), Expect = 2e-04
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C SNPC +G C + C C G CE EV C PC +G C ++ F+
Sbjct: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
Query: 948 C 948
C
Sbjct: 1211 C 1211
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIAN 951
SNPC + G C + F C C +G CE ++ C PC + A C + GF C+
Sbjct: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCM 483
Query: 952 AVFNG 956
F G
Sbjct: 484 PGFKG 488
Score = 44.7 bits (104), Expect = 6e-04
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 2/76 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
++C +PCH+G C D ++C C G C +++ C SPC + +C ++ G++
Sbjct: 572 DNCDPDPCHHGQ-CQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
Query: 948 CIANAVFNGQSGQILF 963
C +G + +I F
Sbjct: 631 CNCQPGTSGVNCEINF 646
Score = 43.9 bits (102), Expect = 0.001
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 885 CAGD-NSCKSNPCHNGGV--CHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQC- 939
C GD N C SNPC + G C +D+ C C + +G+ CE V C PC +G C
Sbjct: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
Query: 940 --QPVLQGFECIANAVFNG 956
+ GF C F+G
Sbjct: 1321 VASNMPDGFICRCPPGFSG 1339
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 894 NPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFECI 949
N C NGG C +R + C C SG C E + C F+ C G+ C + F C+
Sbjct: 307 NACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 891 CKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFE 947
C PC NGG C + D F C CP SG C+ CG C G QC G
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSS--CGQVKCRKGEQCVHTASGPR 1365
Query: 948 CIANAVFNGQSG 959
C + + +SG
Sbjct: 1366 CFCPSPRDCESG 1377
Score = 41.6 bits (96), Expect = 0.005
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 10/82 (12%)
Query: 405 PCQNGGTCENLP-GNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDG 463
PC N G C G C CP L + RD C +C N GTC+ G
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGE-YCQHRD------PCEKNRCQNGGTCVAQAMLG 86
Query: 464 QHGFSCLCPSGYTGSLCEIATT 485
+ +C C SG+TG C+ +T+
Sbjct: 87 KA--TCRCASGFTGEDCQYSTS 106
Score = 41.6 bits (96), Expect = 0.005
Identities = 17/37 (45%), Positives = 23/37 (62%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
V K+ C S PCQ+ G C NL Y+C C + ++G NC
Sbjct: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNC 792
Score = 40.8 bits (94), Expect = 0.009
Identities = 17/34 (50%), Positives = 20/34 (58%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PC + GRCI+L YQC+C G NC
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
Score = 40.8 bits (94), Expect = 0.009
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 654 TLENISSGSSLNVKAGC------VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
T +N+ +G K G V D C S PC ++G C + Y C C PY G NC
Sbjct: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Score = 40.0 bits (92), Expect = 0.016
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPH--GAQCQPVLQ 944
D+ + C NGG C R +SC C +G+ CE ++ C +PC C +
Sbjct: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN 1286
Query: 945 GFECIANAVFNGQ 957
+ C+ + F G+
Sbjct: 1287 DYLCVCRSAFTGR 1299
Score = 38.5 bits (88), Expect = 0.046
Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 9/75 (12%)
Query: 871 NASLNPVLVNVTQGCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE 924
N V VN G +GD+ C C G C R FSC CP +G C
Sbjct: 319 NGGYGCVCVN---GWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL 375
Query: 925 VQWCGFSPCPHGAQC 939
C +PC GA C
Sbjct: 376 DDACISNPCHKGALC 390
Score = 37.7 bits (86), Expect = 0.078
Identities = 12/30 (40%), Positives = 19/30 (63%)
Query: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
S PC+ G+C+N ++ C+C + Y GP C
Sbjct: 424 SNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
Score = 37.0 bits (84), Expect = 0.13
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 888 DNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKACE 923
++ C S+PC +GG CH + +SC C SG CE
Sbjct: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Score = 36.6 bits (83), Expect = 0.17
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC + G C++ +Y+C C Y G NC
Sbjct: 1029 CSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Score = 36.2 bits (82), Expect = 0.23
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S+PC + G C N SY C+C + G +C
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDC 908
Score = 36.2 bits (82), Expect = 0.23
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PCQ C + Y+C+C Y+G NC
Sbjct: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184
Score = 35.0 bits (79), Expect = 0.51
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C++QPCQ+ G CI+L ++C C G C
Sbjct: 1189 DECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222
Score = 34.7 bits (78), Expect = 0.66
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C+S PC + G+C++ +QC C + GP C
Sbjct: 498 CQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVC 529
Score = 34.3 bits (77), Expect = 0.87
Identities = 15/32 (46%), Positives = 18/32 (56%)
Query: 681 CQSRGRCINLWLSYQCDCHRPYEGPNCLREYV 712
CQ G C+NL SYQC C + + G C YV
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV 223
Score = 34.3 bits (77), Expect = 0.87
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S+PC++ G C + SY C C ++G +C
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHC 984
Score = 32.0 bits (71), Expect = 4.3
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 3/69 (4%)
Query: 895 PCHNGGVCHSRWDDFS-CSCPALTSGKACEEVQWCGFSPCPHGAQC--QPVLQGFECIAN 951
PC N G+C + + C CP G+ C+ C + C +G C Q +L C
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCA 93
Query: 952 AVFNGQSGQ 960
+ F G+ Q
Sbjct: 94 SGFTGEDCQ 102
Score = 30.8 bits (68), Expect = 9.6
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 2/34 (5%)
Query: 676 CESQPCQSRGR--CINLWLSYQCDCHRPYEGPNC 707
C S PC S G CI L Y C C + G +C
Sbjct: 1268 CLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC 1301
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 354 bits (908), Expect = 4e-97
Identities = 184/488 (37%), Positives = 227/488 (46%), Gaps = 69/488 (14%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C +N C++ +C STC D C C L +++D C S PC G A C
Sbjct: 352 CEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL---LCHLEDMCLSQPCHGDAQCS 408
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSC-----GKNSCQHGGICHQDPIYPVCICPAGYA 141
P S LC C PGYSG C + C G + C+HGG C P C+CP GY
Sbjct: 409 TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
Query: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
G CE DH+EC S PC G+ C D + + C C PG +G+ C++E +ECAS PC N A C
Sbjct: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
Query: 202 LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
+ + + CIC +SG CE +IDEC S PC NG CQD GA+ C C PGF G C+
Sbjct: 529 HDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
Query: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS-- 319
DEC S PC G C+D + C C SGFTG CE +PLC C C+D
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCP-SGFTGQLCE--VPLCAPNLCQPKQICKDQKD 645
Query: 320 ----------------VDNYTCH----------CWPGYTGAQCEIDLNECNSNPCQSNGE 353
DN TCH C G+TG +CE +L C S PC G
Sbjct: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGT 705
Query: 354 CVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCE 413
C Y + SGY C C G+TG C E++ C S PC NGG+C
Sbjct: 706 C--------------------YPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 414 NLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPS 473
PG Y C CP + G C C C N GTC+ + FSCLC
Sbjct: 746 PSPGGYYCTCP------PSHTGPQCQTSTDYCVSAPCFNGGTCV----NRPGTFSCLCAM 795
Query: 474 GYTGSLCE 481
G+ G CE
Sbjct: 796 GFQGPRCE 803
Score = 327 bits (837), Expect = 6e-89
Identities = 175/517 (33%), Positives = 227/517 (43%), Gaps = 74/517 (14%)
Query: 22 IKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQG 81
++ C C S C N++ C D C C + C+ D C S+PC
Sbjct: 505 LEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSG--TRCEEDIDECRSSPCAN 562
Query: 82 SATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA 141
C + PG +F CKC PG+ G C+T + C + C G C P C+CP+G+
Sbjct: 563 GGQCQDQPG--AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 142 GRFCEIDHDECASSPCQNGAVCQDGID------------------------GY----SCF 173
G+ CE+ CA + CQ +C+D D G+ SC
Sbjct: 621 GQLCEV--PLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCV 678
Query: 174 CVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPC 233
C G+ G C+ E+ C S PC + TC + Y C CP Y+G C E+ C S PC
Sbjct: 679 CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738
Query: 234 LNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGF 293
LNG +C + G Y+C C P G C+ +TD C S PC +GG CV+ +SC C GF
Sbjct: 739 LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC-AMGF 797
Query: 294 TGTHCE-TLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNG 352
G CE L P C PC N ATC+DS C C GYTG C+ ++ C PC N
Sbjct: 798 QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNS 857
Query: 353 ECVE---------------------LSSEKQYGRITGLPSSFSYHEAS-------GYVCI 384
C++ LSS ++ G+ S H Y C
Sbjct: 858 HCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCH 917
Query: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
C PGF G C++ VN C S PCQNG TC P Y C C Y G++CS L
Sbjct: 918 CPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQC------APGYDGQNCSKELDA 971
Query: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
C Q C N+GTC P GF C CP G+ G CE
Sbjct: 972 CQSQPCHNHGTCTPK----PGGFHCACPPGFVGLRCE 1004
Score = 323 bits (827), Expect = 9e-88
Identities = 167/502 (33%), Positives = 230/502 (45%), Gaps = 88/502 (17%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGE 91
C +N C N C C C C+ + CF +P C +C NT G
Sbjct: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEG--HACERDVNECFQDPGPCPKGTSCHNTLG- 216
Query: 92 RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICH----QDPIYPVCICPAGYAGRFCEI 147
SF C CP G G CE G C C +GG C +D + +C+CP G+ G CE+
Sbjct: 217 -SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
Query: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD---PCKNEATCLNE 204
+ D C S CQNG CQDG+D Y+C C + G C +VDEC + C+N TC N
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
Query: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY------------------ 246
G + C+C + G +CE +D+C + C G+TC D +G++
Sbjct: 336 AGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDM 395
Query: 247 ---------------------FCDCAPGFLGDHCELNTDEC-----ASQPCLHGGLCVDG 280
C C PG+ G C + DEC PC HGG C++
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
Query: 281 ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDL 340
++C C G+TG+ CE C S+PCH +TC D + + C C PG G CE++
Sbjct: 456 PGSFNCLCP-PGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVET 514
Query: 341 NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE 400
NEC S PC ++ +C +L +G+ CIC PGF+G CEED++E
Sbjct: 515 NECASAPCLNHADCHDL--------------------LNGFQCICLPGFSGTRCEEDIDE 554
Query: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460
C S+PC NGG C++ PG + C C + G C + C C +C+
Sbjct: 555 CRSSPCANGGQCQDQPGAFHCKC------LPGFEGPRCQTEVDECLSDPCPVGASCL--- 605
Query: 461 QDGQHGFSCLCPSGYTGSLCEI 482
D F CLCPSG+TG LCE+
Sbjct: 606 -DLPGAFFCLCPSGFTGQLCEV 626
Score = 306 bits (785), Expect = 7e-83
Identities = 171/496 (34%), Positives = 227/496 (45%), Gaps = 64/496 (12%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP---CQGSA 83
C N C+S+ CQN TC+D C C +T D C D C + C+
Sbjct: 273 CEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWD--CSEDVDECETQGPPHCRNGG 330
Query: 84 TCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGR 143
TC N+ G SF C C G+ GT CE + C +C G C C+CP G G
Sbjct: 331 TCQNSAG--SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL 388
Query: 144 FCEIDHDECASSPCQNGAVCQDG-IDGYS-CFCVPGYQGRHCDLEVDEC-----ASDPCK 196
C ++ D C S PC A C + G + C C PGY G C ++DEC PC+
Sbjct: 389 LCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
Query: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
+ +CLN G + C+CP Y+G CE + +EC SQPC G+TC D L + C C PG G
Sbjct: 448 HGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEG 507
Query: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATC 316
CE+ T+ECAS PCL+ C D N + C C GF+GT CE + C S PC N C
Sbjct: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICL-PGFSGTRCEEDIDECRSSPCANGGQC 566
Query: 317 EDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYH 376
+D + C C PG+ G +C+ +++EC S+PC C++L P +F
Sbjct: 567 QDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDL------------PGAF--- 611
Query: 377 EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPF---------DN 427
C+C GFTG CE V C+ N CQ C++ C CP DN
Sbjct: 612 -----FCLCPSGFTGQLCE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDN 664
Query: 428 LS-------------RTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSG 474
+ + G +C L GC C + GTC P G++C CP+G
Sbjct: 665 CTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ----PSGYNCTCPTG 720
Query: 475 YTGSLCEIATTLSFEG 490
YTG C T G
Sbjct: 721 YTGPTCSEEMTACHSG 736
Score = 283 bits (725), Expect = 6e-76
Identities = 158/507 (31%), Positives = 214/507 (42%), Gaps = 70/507 (13%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNL--------------------------DKDC 67
C N CQ CKD +C C D + +C
Sbjct: 629 CAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPEC 688
Query: 68 DNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQ 127
+ C S PC TC P + C CP GY+G C + +C C +GG C+
Sbjct: 689 EAELGGCISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNP 746
Query: 128 DPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
P C CP + G C+ D C S+PC NG C + +SC C G+QG C+ ++
Sbjct: 747 SPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL 806
Query: 188 -DECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246
CA PC+N ATC + C+CP Y+G +C+ +D C +PC + C ++
Sbjct: 807 RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866
Query: 247 FCDCAPGFLGDHCELNTDEC----------ASQPCLHGGLCVDGENRYSCNCTGSGFTGT 296
C C G+ G C L C S C +GGLCVD Y C+C GF G+
Sbjct: 867 HCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCP-PGFQGS 925
Query: 297 HCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGEC-- 354
C+ + C S+PC N ATC Y C C PGY G C +L+ C S PC ++G C
Sbjct: 926 LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTP 985
Query: 355 -------------VELSSEKQYGRITGLP-----SSFSYHEASGYVCICQPGFTGIHCEE 396
V L E P ++ + A+ + C C PG TG CE
Sbjct: 986 KPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEV 1045
Query: 397 DVNECSSNPCQNGGTCENLPGN---YTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNN 453
+++ C S PC +GGTCE G+ + CHCP + G CS C C +
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCP------KGFEGPTCSHRAPSCGFHHCHHG 1099
Query: 454 GTCIPHFQDGQHGFSCLCPSGYTGSLC 480
G C+P + G C C SGY G C
Sbjct: 1100 GLCLPSPKPG-FPPRCACLSGYGGPDC 1125
Score = 283 bits (723), Expect = 1e-75
Identities = 159/516 (30%), Positives = 216/516 (41%), Gaps = 75/516 (14%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C C+S C + TC +C+C C C S PC +C
Sbjct: 688 CEAELGGCISAPCAHGGTCYPQPSGYNCTCP--TGYTGPTCSEEMTACHSGPCLNGGSCN 745
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+PG + C CPP ++G C+T+ C C +GG C P C+C G+ G CE
Sbjct: 746 PSPG--GYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
Query: 147 ID-HDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI 205
CA SPC+N A CQD G C C GY G C +D CA PC + CL
Sbjct: 804 GKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG 863
Query: 206 GRYTCICPHNYSGVNCELEIDECW----------SQPCLNGATCQDALGAYFCDCAPGFL 255
+ C+C ++G C L + C S C NG C D+ +YFC C PGF
Sbjct: 864 PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
Query: 256 GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT 315
G C+ + + C S+PC +G C+ + Y C C G+ G +C + C S+PCHN+ T
Sbjct: 924 GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA-PGYDGQNCSKELDACQSQPCHNHGT 982
Query: 316 CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSY 375
C + C C PG+ G +CE D++EC PC G ++ +
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTG------------------TAACH 1024
Query: 376 HEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGN---YTCHCP--FDNLSR 430
A+ + C C PG TG CE +++ C S PC +GGTCE G+ + CHCP F+ +
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Query: 431 TF---------------------------------YGGRDC--SDILLGC-THQQCLNNG 454
+ YGG DC GC CL NG
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNG 1144
Query: 455 TCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEG 490
+C G GF C CP G C+ EG
Sbjct: 1145 SCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEG 1180
Score = 273 bits (698), Expect = 8e-73
Identities = 158/499 (31%), Positives = 223/499 (44%), Gaps = 72/499 (14%)
Query: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVN----------- 87
C N TC S +C L + C F +PCQ + C N
Sbjct: 35 CANGGTCLSLSLGQG-TCQCAPGFLGETCQ------FPDPCQNAQLCQNGGSCQALLPAP 87
Query: 88 -------TPGERSFLCKCPPGYSGTICETTIGS-CGKNSCQHGGICH-QDPIYPVCICPA 138
+P SFLC C PG++G C+ + C + C G CH Q P C C
Sbjct: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
Query: 139 GYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD--PCK 196
G+ G C++ D C+++PC NG VC C C PG++G C+ +V+EC D PC
Sbjct: 148 GWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
Query: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ----DALGAYFCDCAP 252
+C N +G + C+CP G CEL C + C NG TCQ + C C P
Sbjct: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
Query: 253 GFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK---P 309
GF+G CE+N D C S C +GG C DG + Y+C C + +TG C + C ++
Sbjct: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDECETQGPPH 325
Query: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVE-------LSSEKQ 362
C N TC++S ++ C C G+ G CE +L++C + C C++ L +
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGR 385
Query: 363 YGRITGLPSSFSYHEASG------------YVCICQPGFTGIHCEEDVNEC-----SSNP 405
G + L G +C+CQPG++G C +D++EC +P
Sbjct: 386 TGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSP 445
Query: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQH 465
C++GG+C N PG++ C CP Y G C C Q C TC+ D
Sbjct: 446 CEHGGSCLNTPGSFNCLCP------PGYTGSRCEADHNECLSQPCHPGSTCL----DLLA 495
Query: 466 GFSCLCPSGYTGSLCEIAT 484
F CLCP G G LCE+ T
Sbjct: 496 TFHCLCPPGLEGQLCEVET 514
Score = 173 bits (439), Expect = 9e-43
Identities = 79/192 (41%), Positives = 104/192 (54%), Gaps = 8/192 (4%)
Query: 1146 NPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCTCEP 1204
+PC HGG+C + S++C CP G++G CE + +EC S PC G+ C D +A +HC C P
Sbjct: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 503
Query: 1205 GYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKT 1264
G G CEV+ + C S C N A C NG+ C+C F+G C + +E
Sbjct: 504 GLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI-------DECR 556
Query: 1265 NLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCD 1324
+ C NGG C + C C PGF G C+ ++DEC SDPC G C DL F CLC
Sbjct: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCP 616
Query: 1325 VAFAGERCEVDL 1336
F G+ CEV L
Sbjct: 617 SGFTGQLCEVPL 628
Score = 159 bits (401), Expect = 2e-38
Identities = 80/215 (37%), Positives = 109/215 (50%), Gaps = 16/215 (7%)
Query: 1137 CLQLNVCNSNPCLHGGNCED--IYSSYHCSCPLGWSGKHCELNIDECFS-----NPCIHG 1189
C ++C S PC C + S C C G+SG C ++DEC +PC HG
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHG 449
Query: 1190 -NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKF 1248
+C + +++C C PGYTG CE D + C S C G+TC+ + CLC G+
Sbjct: 450 GSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
Query: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
C V NE + C N +C + +C+C PGF+G CE+DIDEC S PC N
Sbjct: 510 CE-------VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCAN 562
Query: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVDLADDLISD 1343
GG CQD F C C F G RC+ ++ D+ +SD
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEV-DECLSD 596
Score = 156 bits (395), Expect = 1e-37
Identities = 73/219 (33%), Positives = 108/219 (49%), Gaps = 20/219 (9%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
++ N C S PCL+ +C D+ + + C C G+SG CE +IDEC S+PC +G C D+
Sbjct: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
A+HC C PG+ G C+ ++D C S C GA+C+ + CLC FTG+ C
Sbjct: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
Query: 1257 TVC--------GNEKTNLTCYNGG--------NCTEFQTELK---CMCRPGFTGEWCEKD 1297
+C +K N C +G NCT + C+C G+TG CE +
Sbjct: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAE 691
Query: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
+ C S PC +GG C + + C C + G C ++
Sbjct: 692 LGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Score = 151 bits (382), Expect = 4e-36
Identities = 71/200 (35%), Positives = 97/200 (48%), Gaps = 7/200 (3%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAA 1197
+L C S PC HGG C S Y+C+CP G++G C + C S PC++G +C+
Sbjct: 691 ELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGG 750
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Y+CTC P +TG C+ D C S C NG TC++ +SCLC F G C PS
Sbjct: 751 YYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPS- 809
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
C + C N C + +C+C G+TG C+ +D CA PC C
Sbjct: 810 -CADS----PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
Query: 1318 KFQCLCDVAFAGERCEVDLA 1337
F CLC + G C + L+
Sbjct: 865 SFHCLCLQGWTGPLCNLPLS 884
Score = 142 bits (357), Expect = 3e-33
Identities = 71/210 (33%), Positives = 99/210 (47%), Gaps = 20/210 (9%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC----------FSNPCIHG 1189
+++C PC +C S+HC C GW+G C L + C S+ C +G
Sbjct: 845 MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
Query: 1190 N-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKF 1248
C D +Y C C PG+ G C+ ++ C+S C NGATC++ +GY C C + G+
Sbjct: 905 GLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQN 964
Query: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
C + C ++ C+N G CT C C PGF G CE D+DEC PC
Sbjct: 965 CSKE---LDACQSQ----PCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
Query: 1309 GG--LCQDLLNKFQCLCDVAFAGERCEVDL 1336
G C L N F C C G+ CEV++
Sbjct: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEVEI 1047
Score = 139 bits (349), Expect = 2e-32
Identities = 74/244 (30%), Positives = 105/244 (43%), Gaps = 49/244 (20%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECF-------------- 1182
C + C++NPC++GG C Y C CP G+ G CE +++ECF
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
Query: 1183 ---------------------SNPCIHGNCS---------DRVAAYH-CTCEPGYTGVNC 1211
+ PC CS ++ + +H C C PG+ G +C
Sbjct: 214 TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC 273
Query: 1212 EVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNG 1271
EV+ DNC SHQC NG TC + Y+CLC +TG C + G C NG
Sbjct: 274 EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH----CRNG 329
Query: 1272 GNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGER 1331
G C C+C G+ G CE+++D+C + C G C D + F CLC G
Sbjct: 330 GTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLL 389
Query: 1332 CEVD 1335
C ++
Sbjct: 390 CHLE 393
Score = 137 bits (346), Expect = 6e-32
Identities = 73/224 (32%), Positives = 101/224 (45%), Gaps = 38/224 (16%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI----------H 1188
+++ C S+PC G +C D+ ++ C CP G++G+ CE+ + C N C
Sbjct: 589 EVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDK 646
Query: 1189 GNC------------SDRVAAYH-------CTCEPGYTGVNCEVDIDNCQSHQCANGATC 1229
NC D +H C C+ G+TG CE ++ C S CA+G TC
Sbjct: 647 ANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTC 706
Query: 1230 ISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
+GY+C C +TG C + T C + C NGG+C C C P
Sbjct: 707 YPQPSGYNCTCPTGYTGPTCSEEM---TACHSGP----CLNGGSCNPSPGGYYCTCPPSH 759
Query: 1290 TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
TG C+ D C S PC NGG C + F CLC + F G RCE
Sbjct: 760 TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
Score = 135 bits (339), Expect = 4e-31
Identities = 100/333 (30%), Positives = 133/333 (39%), Gaps = 94/333 (28%)
Query: 231 QPCLNGATCQD-ALGAYFCDCAPGFLGDHCELNTDECA-SQPCLHGGLC----------- 277
+PC NG TC +LG C CAPGFLG+ C+ D C +Q C +GG C
Sbjct: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQF-PDPCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 278 -----------------VDGE----------------NRYSCNCTGS---------GFTG 295
GE R C+ S G+TG
Sbjct: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
Query: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNEC--NSNPCQSNGE 353
C+ L C + PC N C + CHC PG+ G CE D+NEC + PC
Sbjct: 152 EQCQ-LRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS 210
Query: 354 CVE-------LSSEKQYGRITGLPSS---------------FSYHEASGYVCICQPGFTG 391
C L Q G L + +++ ++C+C PGF G
Sbjct: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIG 270
Query: 392 IHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQ--- 448
CE + + C S+ CQNGGTC++ YTC CP + G DCS+ + C Q
Sbjct: 271 PDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCP------ETWTGWDCSEDVDECETQGPP 324
Query: 449 QCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
C N GTC Q+ F C+C SG+ G+ CE
Sbjct: 325 HCRNGGTC----QNSAGSFHCVCVSGWGGTSCE 353
Score = 134 bits (338), Expect = 5e-31
Identities = 93/340 (27%), Positives = 131/340 (38%), Gaps = 28/340 (8%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ S C + C S CQN +TC C C+ + ++C D C S PC
Sbjct: 923 QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQSQPCHNH 980
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGG--ICHQDPIYPVCICPAGY 140
TC PG F C CPPG+ G CE + C C G CH C C G+
Sbjct: 981 GTCTPKPG--GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGH 1038
Query: 141 AGRFCEIDHDECASSPCQNGAVCQDGID---GYSCFCVPGYQGRHCDLEVDECASDPCKN 197
G++CE++ D C S PC +G C+ G+ C C G++G C C C +
Sbjct: 1039 TGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHH 1098
Query: 198 EATCLNEIG---RYTCICPHNYSGVNC--ELEIDECW-SQPCLNGATCQDALG----AYF 247
CL C C Y G +C C PCL +C + G +
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFR 1158
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
C C G C+ + ++ C G DG C+ G + G C +P W
Sbjct: 1159 CSCPHSSPGPRCQ----KPGAKGC--EGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPW- 1211
Query: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP 347
K C +++ C + CH P +C D +C + P
Sbjct: 1212 KGCPSHSRCWLLFRDGQCH--PQCDSEECLFDGYDCETPP 1249
Score = 133 bits (335), Expect = 1e-30
Identities = 66/209 (31%), Positives = 91/209 (43%), Gaps = 18/209 (8%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCT 1201
C +PC + C+D C CP G++G C+ +D C PC + +C ++HC
Sbjct: 810 CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCL 869
Query: 1202 CEPGYTGVNCEVDIDNCQ----------SHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
C G+TG C + + +CQ S C NG C+ Y C C F G C+
Sbjct: 870 CLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD 929
Query: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
P + C NG C + C C PG+ G+ C K++D C S PC N G
Sbjct: 930 HVNPCE-------SRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGT 982
Query: 1312 CQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
C F C C F G RCE D+ + L
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECL 1011
Score = 124 bits (310), Expect = 8e-28
Identities = 65/202 (32%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAY 1198
+N C S PC +G C S Y C C G+ G++C +D C S PC HG C+ + +
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGF 990
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQC--ANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
HC C PG+ G+ CE D+D C C A C S N + C C TG++C P
Sbjct: 991 HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP- 1049
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTE---LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQ 1313
C ++ C++GG C C C GF G C C C +GGLC
Sbjct: 1050 --CHSQ----PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCL 1103
Query: 1314 DLLNKF---QCLCDVAFAGERC 1332
+C C + G C
Sbjct: 1104 PSPKPGFPPRCACLSGYGGPDC 1125
Score = 122 bits (306), Expect = 2e-27
Identities = 70/202 (34%), Positives = 90/202 (44%), Gaps = 16/202 (7%)
Query: 1143 CNSNPCLHGGNCEDIYSSY-HCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHC 1200
C + C G C S CSC GW+G+ C+L D C +NPC++G C C
Sbjct: 122 CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQC 180
Query: 1201 TCEPGYTGVNCEVDIDNC--QSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C PG+ G CE D++ C C G +C + + CLC G C P
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP 240
Query: 1259 CGNEKTNLTCYNGGNCT----EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
G C NGG C + T C+C PGF G CE + D C S C NGG CQD
Sbjct: 241 RG-------CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
Query: 1315 LLNKFQCLCDVAFAGERCEVDL 1336
L+ + CLC + G C D+
Sbjct: 294 GLDTYTCLCPETWTGWDCSEDV 315
Score = 115 bits (287), Expect = 4e-25
Identities = 70/211 (33%), Positives = 94/211 (44%), Gaps = 23/211 (10%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI---HGNCSDRV 1195
+L+ C S PC + G C +HC+CP G+ G CE ++DEC PC C
Sbjct: 968 ELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLA 1027
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN---GYSCLCFGNFTGKFCRQS 1252
A++C C PG+TG CEV+ID C S C +G TC + G+ C C F G C
Sbjct: 1028 NAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC-SH 1086
Query: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQT---ELKCMCRPGFTGEWC--EKDIDECA-SDPC 1306
R PS CG C++GG C +C C G+ G C C PC
Sbjct: 1087 RAPS--CGFHH----CHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
Query: 1307 VNGGLCQDLLN----KFQCLCDVAFAGERCE 1333
+ G C + F+C C + G RC+
Sbjct: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ 1171
Score = 94.4 bits (233), Expect = 7e-19
Identities = 62/204 (30%), Positives = 83/204 (40%), Gaps = 52/204 (25%)
Query: 1182 FSNPCIHGNC--SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ-CANGATCIS------- 1231
F PC +G S + C C PG+ G C+ D CQ+ Q C NG +C +
Sbjct: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLG 89
Query: 1232 -------HTNGYSCLCFGNFTGKFCR---QSRLPSTVCG--------------------- 1260
T + C C FTG+ C+ + P + C
Sbjct: 90 LPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW 149
Query: 1261 -NEKTNL-------TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASD--PCVNGG 1310
E+ L C NGG C +++C C PGF G CE+D++EC D PC G
Sbjct: 150 TGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGT 209
Query: 1311 LCQDLLNKFQCLCDVAFAGERCEV 1334
C + L FQCLC V G RCE+
Sbjct: 210 SCHNTLGSFQCLCPVGQEGPRCEL 233
Score = 84.3 bits (207), Expect = 7e-16
Identities = 68/223 (30%), Positives = 92/223 (41%), Gaps = 31/223 (13%)
Query: 304 LCWS--KPCHNNATCED-SVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE 360
LC S +PC N TC S+ TC C PG+ G C+ N+ CQ+ G C L
Sbjct: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPA 86
Query: 361 KQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTCE-NLPGN 418
GLPSS S S ++C C PGFTG C+ + + C + C G C G
Sbjct: 87 P-----LGLPSSPSPLTPS-FLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGR 140
Query: 419 YTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGS 478
C C + G C + C+ C+N G C+ + Q C CP G+ G
Sbjct: 141 PQCSC------MPGWTGEQCQ-LRDFCSANPCVNGGVCLATYPQIQ----CHCPPGFEGH 189
Query: 479 LCEIATTLSFEGDGFLWVKSGSVTTKGSVCNIAL-RFQTVQPM 520
CE F+ G KG+ C+ L FQ + P+
Sbjct: 190 ACERDVNECFQDPG--------PCPKGTSCHNTLGSFQCLCPV 224
Score = 61.6 bits (148), Expect = 5e-09
Identities = 29/72 (40%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 886 AGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ 944
A N C S PCH G C F C CP G+ CE E C +PC + A C +L
Sbjct: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN 533
Query: 945 GFECIANAVFNG 956
GF+CI F+G
Sbjct: 534 GFQCICLPGFSG 545
Score = 57.8 bits (138), Expect = 7e-08
Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWC--GFSPCPHGAQCQP 941
C + C +NPC NGGVC + + C CP G ACE +V C PCP G C
Sbjct: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
Query: 942 VLQGFECIANAVFNGQSG 959
L F+C+ GQ G
Sbjct: 214 TLGSFQCLCPV---GQEG 228
Score = 56.2 bits (134), Expect = 2e-07
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C+S+PC NGG C + F C C G C+ EV C PCP GA C + F
Sbjct: 553 DECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612
Query: 948 CIANAVFNGQ 957
C+ + F GQ
Sbjct: 613 CLCPSGFTGQ 622
Score = 54.3 bits (129), Expect = 8e-07
Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
N C S PC N CH + F C C SG CEE + C SPC +G QCQ F
Sbjct: 515 NECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574
Query: 948 CIANAVFNG 956
C F G
Sbjct: 575 CKCLPGFEG 583
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/87 (37%), Positives = 37/87 (42%), Gaps = 17/87 (19%)
Query: 1268 CYNGGNCTEFQT-ELKCMCRPGFTGEWCEKDIDECASDP-CVNGGLCQDLLN-------- 1317
C NGG C + C C PGF GE C+ D C + C NGG CQ LL
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
Query: 1318 ------KFQCLCDVAFAGERCEVDLAD 1338
F C C F GERC+ L D
Sbjct: 94 PSPLTPSFLCTCLPGFTGERCQAKLED 120
Score = 53.1 bits (126), Expect = 2e-06
Identities = 30/74 (40%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV--QWCGFSPCPHGAQCQPVLQGFEC 948
C S PC NGG C +R FSC C G CE C SPC + A CQ QG C
Sbjct: 771 CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830
Query: 949 IANAVFNGQSGQIL 962
+ + G S Q L
Sbjct: 831 LCPTGYTGGSCQTL 844
Score = 53.1 bits (126), Expect = 2e-06
Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 14/128 (10%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSS---YHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSD 1193
++++ C+S PC HGG CE S + C CP G+ G C C + C HG C
Sbjct: 1045 VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLP 1104
Query: 1194 RVA---AYHCTCEPGYTGVNCEVD--IDNC-QSHQCANGATCISHTN----GYSCLCFGN 1243
C C GY G +C C C +C T G+ C C +
Sbjct: 1105 SPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHS 1164
Query: 1244 FTGKFCRQ 1251
G C++
Sbjct: 1165 SPGPRCQK 1172
Score = 52.8 bits (125), Expect = 2e-06
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFEC 948
C S PC +GG C+ + ++C+CP +G C EE+ C PC +G C P G+ C
Sbjct: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
Score = 50.1 bits (118), Expect = 2e-05
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIAN 951
S+ CHNGG+C + C CP G C++ V C PC +GA C G+ C
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
Query: 952 AVFNGQS 958
++GQ+
Sbjct: 958 PGYDGQN 964
Score = 49.7 bits (117), Expect = 2e-05
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC---GFSPCPHGAQCQPVLQ 944
++C S+ C NGG C D ++C CP +G C E+V C G C +G CQ
Sbjct: 278 DNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
Query: 945 GFECIANAVFNGQS 958
F C+ + + G S
Sbjct: 338 SFHCVCVSGWGGTS 351
Score = 49.3 bits (116), Expect = 3e-05
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
N C+S PC NG C ++ + C C G+ C +E+ C PC + C P GF
Sbjct: 932 NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991
Query: 948 CIANAVFNG 956
C F G
Sbjct: 992 CACPPGFVG 1000
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 883 QGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPC-PHG-AQ 938
Q C+ + ++C+S PCHN G C + F C+CP G CE +V C PC P G A
Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAA 1022
Query: 939 CQPVLQGFEC 948
C + F C
Sbjct: 1023 CHSLANAFYC 1032
Score = 48.1 bits (113), Expect = 6e-05
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFEC 948
+C S PC NGG C+ + C+CP +G C+ +C +PC +G C F C
Sbjct: 732 ACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
Query: 949 IANAVFNG 956
+ F G
Sbjct: 792 LCAMGFQG 799
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 885 CAGD-NSCKSNPCHNGGV--CHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQ 940
C GD + C PCH G CHS + F C C +G+ CE E+ C PC HG C+
Sbjct: 1003 CEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
Query: 941 PVL---QGFECIANAVFNG 956
GF C F G
Sbjct: 1063 ATAGSPLGFICHCPKGFEG 1081
Score = 45.8 bits (107), Expect = 3e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 894 NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANA 952
+PC +GG C + F+C CP +G CE + C PC G+ C +L F C+
Sbjct: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 503
Query: 953 VFNGQ 957
GQ
Sbjct: 504 GLEGQ 508
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 4/55 (7%)
Query: 891 CKSNPCHNGGVCHSRWDD---FSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQP 941
C S PC +GG C + F C CP G C CGF C HG C P
Sbjct: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLP 1104
Score = 42.7 bits (99), Expect = 0.002
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFEC 948
SC +PC N C C CP +G +C+ + C PCP + C F C
Sbjct: 809 SCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHC 868
Query: 949 I 949
+
Sbjct: 869 L 869
Score = 40.8 bits (94), Expect = 0.009
Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 9/79 (11%)
Query: 887 GDNSCKSN-------PCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
G SC+ N C G C R FSC CP +G C C PC AQC
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQC 407
Query: 940 --QPVLQGFECIANAVFNG 956
P+ C+ ++G
Sbjct: 408 STNPLTGSTLCLCQPGYSG 426
Score = 40.8 bits (94), Expect = 0.009
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 884 GCAG-DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQP 941
GCA +++C CH+G S SC C +G CE E+ C +PC HG C P
Sbjct: 657 GCAPPEDNCT---CHHGHCQRS-----SCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
Query: 942 VLQGFECIANAVFNG 956
G+ C + G
Sbjct: 709 QPSGYNCTCPTGYTG 723
Score = 39.3 bits (90), Expect = 0.027
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 8/80 (10%)
Query: 885 CAGDNSCKSNPCHNGGVCHSR--WDDFSCSCPALTSGKAC-EEVQWC-----GFSPCPHG 936
C ++ C S PCH C + C C SG C +++ C G SPC HG
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHG 449
Query: 937 AQCQPVLQGFECIANAVFNG 956
C F C+ + G
Sbjct: 450 GSCLNTPGSFNCLCPPGYTG 469
Score = 38.9 bits (89), Expect = 0.035
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECI 949
C NGG C + F C C + G +CEE + C + C G+ C + F C+
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCL 380
Score = 38.9 bits (89), Expect = 0.035
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
CES+PCQ+ C+ Y C C Y+G NC +E
Sbjct: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKE 968
Score = 37.7 bits (86), Expect = 0.078
Identities = 35/122 (28%), Positives = 44/122 (36%), Gaps = 9/122 (7%)
Query: 591 CIAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDW 650
C A P PL S SFL G T G P PSF K
Sbjct: 80 CQALLPAPLGLPSSPSPLTPSFLCTCLPGFT--GERCQAKLEDPCPPSFCS-----KRGR 132
Query: 651 NHITLENISSGSSLNVKAG--CVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL 708
HI S + G C +D+C + PC + G C+ + QC C +EG C
Sbjct: 133 CHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE 192
Query: 709 RE 710
R+
Sbjct: 193 RD 194
Score = 36.6 bits (83), Expect = 0.17
Identities = 13/34 (38%), Positives = 20/34 (58%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D+C S PC + G C+N ++ C C ++GP C
Sbjct: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRC 802
Score = 36.2 bits (82), Expect = 0.23
Identities = 18/72 (25%), Positives = 30/72 (41%), Gaps = 1/72 (1%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDF-SCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGF 946
++ C + C G CH + CSC +G+ C+ +C +PC +G C
Sbjct: 119 EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQI 178
Query: 947 ECIANAVFNGQS 958
+C F G +
Sbjct: 179 QCHCPPGFEGHA 190
Score = 36.2 bits (82), Expect = 0.23
Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 895 PCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQ 940
PC G CH+ F C CP G CE C C +G CQ
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQ 250
Score = 35.4 bits (80), Expect = 0.39
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
D C S PC + G+C + ++ C C +EGP C E
Sbjct: 553 DECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE 589
Score = 34.7 bits (78), Expect = 0.66
Identities = 16/42 (38%), Positives = 16/42 (38%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFG 717
C S PC G C Y C C Y GP C E A G
Sbjct: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
Score = 32.7 bits (73), Expect = 2.5
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Query: 671 VRKDWCESQPCQSRGRC---INLWLSYQCDCHRPYEGPNC 707
V D C SQPC G C L + C C + +EGP C
Sbjct: 1045 VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 32.3 bits (72), Expect = 3.3
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFEC 948
+ C S+PC G C F C CP+ +G+ C EV C + C C+ C
Sbjct: 591 DECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLC-EVPLCAPNLCQPKQICKDQKDKANC 649
Query: 949 I 949
+
Sbjct: 650 L 650
Score = 32.0 bits (71), Expect = 4.3
Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 2/40 (5%)
Query: 670 CVRKDWCESQPCQSRGRCIN--LWLSYQCDCHRPYEGPNC 707
C +D C SQPC +C L S C C Y GP C
Sbjct: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429
Score = 31.2 bits (69), Expect = 7.3
Identities = 11/34 (32%), Positives = 16/34 (47%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C +PC C+ S+ C C + + GP C
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 351 bits (900), Expect = 3e-96
Identities = 170/456 (37%), Positives = 236/456 (51%), Gaps = 39/456 (8%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C++N C + C + +TC D C+C L ++ D C SNPC A C
Sbjct: 311 CSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGL---LCHLDDACVSNPCHEDAICD 367
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSC--GKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
P +C CPPG++G C+ + C G N C+H G C +C C GY G
Sbjct: 368 TNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPR 427
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
CE D +EC S PC+N A C D I ++C C+ G+ G +C++++DEC S PC N C +
Sbjct: 428 CETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR 487
Query: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
+ ++C CP +SG C+L++DEC S PC NGA C D Y C CA GF G C+ N D
Sbjct: 488 VNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVD 547
Query: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
+C+ PC H G CVDG +SC C G+TGT CE+ + C S+PC + C D VD Y
Sbjct: 548 DCSPDPC-HHGRCVDGIASFSCAC-APGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
Query: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
C C G TG CE+++++C SNPC + G C + + Y C+
Sbjct: 606 CRCPSGTTGVNCEVNIDDCASNPC-TFGVCRD--------------------GINRYDCV 644
Query: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
CQPGFTG C ++NEC+S+PC GG+C + + C CP +L C
Sbjct: 645 CQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL------CLPPSHP 698
Query: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
C H+ C ++G C D GF C+C G++G C
Sbjct: 699 CAHEPC-SHGIC----YDAPGGFRCVCEPGWSGPRC 729
Score = 335 bits (860), Expect = 1e-91
Identities = 170/494 (34%), Positives = 242/494 (48%), Gaps = 82/494 (16%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPC-FSNPCQGSATCVNTPGER 92
CLS+ C + + C D CS + C + D C PC+ TC+NTPG
Sbjct: 123 CLSSPCAHGARCS-VGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPG-- 179
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQ--DPIYPVCICPAGYAGRFCEIDHD 150
SF C+CP GY+G +CE C + C++GG C Q D Y C C G+ G+ CE++ D
Sbjct: 180 SFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYD-CACLPGFEGQNCEVNVD 238
Query: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDP--CKNEATCLNEIGRY 208
+C C NG C DG++ Y+C C P + G+ C +VDEC P C N TC N +G +
Sbjct: 239 DCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGH 298
Query: 209 TCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFC-------------------- 248
+C+C + ++G +C ID+C + C +GATC D + +++C
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 358
Query: 249 -------------------DCAPGFLGDHCELNTDECA--SQPCLHGGLCVDGENRYSCN 287
C PGF G C+ + DEC+ + PC H G CV+ + + C
Sbjct: 359 PCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQ 418
Query: 288 CTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP 347
C G G+TG CET + C S PC N ATC D + +TC C G+TG CE+D++EC S+P
Sbjct: 419 C-GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSP 477
Query: 348 CQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQ 407
C + G C + +G+ C C GF+G C+ DV+EC+S PC+
Sbjct: 478 CVNGGVCKD--------------------RVNGFSCTCPSGFSGSTCQLDVDECASTPCR 517
Query: 408 NGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGF 467
NG C + P Y C C + G C + C+ C ++G C+ DG F
Sbjct: 518 NGAKCVDQPDGYECRCAEG------FEGTLCDRNVDDCSPDPC-HHGRCV----DGIASF 566
Query: 468 SCLCPSGYTGSLCE 481
SC C GYTG+ CE
Sbjct: 567 SCACAPGYTGTRCE 580
Score = 329 bits (843), Expect = 1e-89
Identities = 172/459 (37%), Positives = 227/459 (49%), Gaps = 44/459 (9%)
Query: 34 CLSNSCQNNSTCKDFSKDNDC--SCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGE 91
C S C C+ SC DC ++ DPC S+PC A C P
Sbjct: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC-SLPDPCLSSPCAHGARCSVGPDG 140
Query: 92 RSFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQDPIYPVCICPAGYAGRFCEIDHD 150
R FLC CPPGY G C + + C C+HGG C P C CPAGY G CE
Sbjct: 141 R-FLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV 199
Query: 151 ECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
CA SPC+NG C Q G Y C C+PG++G++C++ VD+C C N TC++ + Y
Sbjct: 200 PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 259
Query: 210 CICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECA 267
C CP ++G C ++DEC QP C NG TC + LG + C C G+ G+ C N D+CA
Sbjct: 260 CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCA 319
Query: 268 SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN--YTC 325
+ C HG C D + C C G TG C L C S PCH +A C+ + N C
Sbjct: 320 TAVCFHGATCHDRVASFYCACP-MGKTGLLCH-LDDACVSNPCHEDAICDTNPVNGRAIC 377
Query: 326 HCWPGYTGAQCEIDLNECN--SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383
C PG+TG C+ D++EC+ +NPC+ G CV ++C
Sbjct: 378 TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS--------------------FLC 417
Query: 384 ICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL 443
C G+TG CE DVNEC S PC+N TC + G +TC C + G C +
Sbjct: 418 QCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCIC------MAGFTGTYCEVDID 471
Query: 444 GCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
C C+N G C +D +GFSC CPSG++GS C++
Sbjct: 472 ECQSSPCVNGGVC----KDRVNGFSCTCPSGFSGSTCQL 506
Score = 328 bits (841), Expect = 2e-89
Identities = 164/469 (34%), Positives = 226/469 (48%), Gaps = 51/469 (10%)
Query: 27 CNKNNTR--CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
C+++ R C S C+ TC C+C + C+ + PC NPC+
Sbjct: 729 CSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQG--RQCE-LLSPCTPNPCEHGGR 785
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSC-GKNSCQHGGICHQDPIYPVCICPAGYAGR 143
C + PG+ +C CP G+ G C+ + C G C GIC C C GY G
Sbjct: 786 CESAPGQLP-VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGP 844
Query: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
C+ D ++C +PC NG CQDG+ +SC C+PG+ G C +VDEC S+PC TC +
Sbjct: 845 SCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTD 903
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 263
+ +TC CP Y G +CE ++ +C C NG TC D + ++ C C PG+ G HC+
Sbjct: 904 HVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEA 963
Query: 264 DECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNY 323
D C S+PCLHGG+C + C C S FTG C+TL+ C +PC N C +
Sbjct: 964 DPCLSRPCLHGGVCSAAHPGFRCTCLES-FTGPQCQTLVDWCSRQPCQNGGRCVQT--GA 1020
Query: 324 TCHCWPGYTGAQCEIDLNECNSNP----------CQSNGECVELSSEKQYGRITGLPSSF 373
C C PG++G C+I C CQ+ G+CV+
Sbjct: 1021 YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD----------------- 1063
Query: 374 SYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFY 433
E S + C+C G TG HCE++V+ C + PCQ+GGTC G Y C C Y
Sbjct: 1064 ---EDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCEC------LPGY 1114
Query: 434 GGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
G +C D + C Q C + G+CI D + C CP G G LCEI
Sbjct: 1115 NGDNCEDDVDECASQPCQHGGSCI----DLVARYLCSCPPGTLGVLCEI 1159
Score = 313 bits (802), Expect = 7e-85
Identities = 165/510 (32%), Positives = 231/510 (45%), Gaps = 66/510 (12%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
++C + C S+ C N CKD + N SC+ + C D C S PC+ A
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKD--RVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAK 521
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
CV+ P + C+C G+ GT+C+ + C + C HG C C C GY G
Sbjct: 522 CVDQPD--GYECRCAEGFEGTLCDRNVDDCSPDPCHHGR-CVDGIASFSCACAPGYTGTR 578
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
CE DEC S PC++G C D +D Y C C G G +C++ +D+CAS+PC C +
Sbjct: 579 CESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDG 637
Query: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
I RY C+C ++G C +EI+EC S PC G +C D + C C PG L C +
Sbjct: 638 INRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSH 697
Query: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM--PLCWSKPCHNNATCEDSVDN 322
CA +PC H G+C D + C C G++G C + C S+PC TC
Sbjct: 698 PCAHEPCSH-GICYDAPGGFRCVCE-PGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 755
Query: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGEC--------------------VELSSEKQ 362
+ C C PG G QCE+ L+ C NPC+ G C + ++
Sbjct: 756 FHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDEC 814
Query: 363 YGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCH 422
G P + A + C C G+TG C++D+N+C NPC NGG+C++ G+++C
Sbjct: 815 AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCS 874
Query: 423 C-------------------------------PFDNLSRTFYGGRDCSDILLGCTHQQCL 451
C F YGG C L C+ C
Sbjct: 875 CLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCF 934
Query: 452 NNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
N GTC+ DG + FSCLC GYTG+ C+
Sbjct: 935 NGGTCV----DGVNSFSCLCRPGYTGAHCQ 960
Score = 284 bits (727), Expect = 4e-76
Identities = 158/477 (33%), Positives = 206/477 (43%), Gaps = 46/477 (9%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C ++ C +SC N TC D C C C + DPC S PC C
Sbjct: 921 CEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAH--CQHEADPCLSRPCLHGGVC- 977
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ F C C ++G C+T + C + CQ+GG C Q Y C+CP G++GR C+
Sbjct: 978 -SAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY--CLCPPGWSGRLCD 1034
Query: 147 IDHDECASSP----------CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
I C + CQ G C D + C C G G HC+ EVD C + PC+
Sbjct: 1035 IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQ 1094
Query: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
+ TC +G Y C C Y+G NCE ++DEC SQPC +G +C D + Y C C PG LG
Sbjct: 1095 HGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLG 1154
Query: 257 DHCELNTDECASQP-------CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP 309
CE+N D+C P CLH G CVD + C C G+TG CE + C S
Sbjct: 1155 VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP-PGYTGLRCEADINECRSGA 1213
Query: 310 CHNNAT---CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRI 366
CH T +D + C C G++G +C+ L+ C S PCQ G+C S G +
Sbjct: 1214 CHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQC--RPSPGPGGGL 1271
Query: 367 TGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP-- 424
T + C C F G CE C C G C+ P C CP
Sbjct: 1272 T-------------FTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPG 1318
Query: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
S + G C CL+ G+C P F C C G+TG CE
Sbjct: 1319 LSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP--APLAPFFRCACAQGWTGPRCE 1373
Score = 284 bits (726), Expect = 5e-76
Identities = 156/506 (30%), Positives = 217/506 (42%), Gaps = 94/506 (18%)
Query: 34 CLSNSCQNNSTCKDFSKDND-CSCSD--TANNLDKDCDNMKDPCFSNPCQGSATCVNTPG 90
C N C++ C+ CSC +D D P PC C N G
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPA---PCGPHGICTNLAG 831
Query: 91 ERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHD 150
SF C C GY+G C+ I C N C +GG C C C G+AG C D D
Sbjct: 832 --SFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVD 889
Query: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 210
EC S+PC G C D + ++C C PGY G HC+ ++ +C+ C N TC++ + ++C
Sbjct: 890 ECLSNPCGPGT-CTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC 948
Query: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270
+C Y+G +C+ E D C S+PCL+G C A + C C F G C+ D C+ QP
Sbjct: 949 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP 1008
Query: 271 CLH----------------------------------------------GGLCVDGENRY 284
C + GG CVD ++ +
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1068
Query: 285 SCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECN 344
C C G TG+HCE + C ++PC + TC + Y C C PGY G CE D++EC
Sbjct: 1069 YCVCP-EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECA 1127
Query: 345 SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSN 404
S PCQ G C++L + Y+C C PG G+ CE + ++C
Sbjct: 1128 SQPCQHGGSCIDL--------------------VARYLCSCPPGTLGVLCEINEDDCGPG 1167
Query: 405 P-------CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC--LNNGT 455
P C + GTC +L G + C CP Y G C + C C +
Sbjct: 1168 PPLDSGPRCLHNGTCVDLVGGFRCTCP------PGYTGLRCEADINECRSGACHAAHTRD 1221
Query: 456 CIPHFQDGQHGFSCLCPSGYTGSLCE 481
C+ QD GF CLC +G++G C+
Sbjct: 1222 CL---QDPGGGFRCLCHAGFSGPRCQ 1244
Score = 179 bits (454), Expect = 2e-44
Identities = 77/195 (39%), Positives = 109/195 (55%), Gaps = 9/195 (4%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYH 1199
+N C+ NPCL+GG+C+D S+ CSC G++G C ++DEC SNPC G C+D VA++
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
CTC PGY G +CE D+ +C C NG TC+ N +SCLC +TG C+ P
Sbjct: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC--- 966
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
+ C +GG C+ +C C FTG C+ +D C+ PC NGG C +
Sbjct: 967 ----LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGA 1020
Query: 1320 QCLCDVAFAGERCEV 1334
CLC ++G C++
Sbjct: 1021 YCLCPPGWSGRLCDI 1035
Score = 176 bits (447), Expect = 1e-43
Identities = 77/200 (38%), Positives = 112/200 (56%), Gaps = 9/200 (4%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
+N C S PC + C D + C C G++G +CE++IDEC S+PC++G C DRV +
Sbjct: 432 VNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF 491
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
CTC G++G C++D+D C S C NGA C+ +GY C C F G C ++
Sbjct: 492 SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV----- 546
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
++ + C++G C + C C PG+TG CE +DEC S PC +GG C DL++K
Sbjct: 547 --DDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603
Query: 1319 FQCLCDVAFAGERCEVDLAD 1338
+ C C G CEV++ D
Sbjct: 604 YLCRCPSGTTGVNCEVNIDD 623
Score = 167 bits (423), Expect = 7e-41
Identities = 129/474 (27%), Positives = 166/474 (35%), Gaps = 93/474 (19%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
S C + CL+ CQ+ TC+ + C C N +C++ D C S PCQ +
Sbjct: 1079 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNG--DNCEDDVDECASQPCQHGGS 1136
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKN-------SCQHGGICHQDPIYPVCICP 137
C++ +LC CPPG G +CE CG C H G C C CP
Sbjct: 1137 CIDLVAR--YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194
Query: 138 AGYAGRFCEIDHDECASSPCQNGAV---CQDGIDGYSCFCVPGYQGRHCDLEVDECASDP 194
GY G CE D +EC S C QD G+ C C G+ G C + C S P
Sbjct: 1195 PGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
Query: 195 CKNEATCLNEIG-----RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
C++ C G +TC C + G CE C C G CQ C
Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCA 1314
Query: 250 CAPGFLGDHCE--------LNTDECASQPCLHGGLCVDGENR--YSCNCTGSGFTGTHCE 299
C PG G C + CA+ PCLHGG C + C C G+TG CE
Sbjct: 1315 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCAC-AQGWTGPRCE 1373
Query: 300 --TLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL 357
P +P A C+ + C ECNS C +G L
Sbjct: 1374 APAAAPEVSEEPRCPRAACQAKRGDQRCD--------------RECNSPGCGWDGGDCSL 1419
Query: 358 SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPG 417
S + + L C F C+ CSS C L
Sbjct: 1420 SVGDPWRQCEALQ--------------CWRLFNNSRCDP---ACSSPAC--------LYD 1454
Query: 418 NYTCHCPFDNLSRTFYGGRD--CSDILLGCTHQQCLNNGTCIPHFQDGQHGFSC 469
N+ CH GGR+ C+ + C HF DG+ C
Sbjct: 1455 NFDCHA----------GGRERTCNPVY----------EKYCADHFADGRCDQGC 1488
Score = 166 bits (420), Expect = 1e-40
Identities = 76/198 (38%), Positives = 102/198 (51%), Gaps = 10/198 (5%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY 1198
Q++ C S PC HGG C D+ Y C CP G +G +CE+NID+C SNPC G C D + Y
Sbjct: 582 QVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRY 641
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C+PG+TG C V+I+ C S C G +C+ NG+ CLC C PS
Sbjct: 642 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP---PSHP 698
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI--DECASDPCVNGGLCQDLL 1316
C +E + G C + +C+C PG++G C + + D C S PC GG C
Sbjct: 699 CAHEPC-----SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDG 753
Query: 1317 NKFQCLCDVAFAGERCEV 1334
F C C G +CE+
Sbjct: 754 MGFHCTCPPGVQGRQCEL 771
Score = 165 bits (417), Expect = 3e-40
Identities = 79/211 (37%), Positives = 106/211 (50%), Gaps = 16/211 (7%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYH-CSCPLGWSGKHCELNIDECFS-NPC-IHGNCSD 1193
C L+ C NPC HGG CE CSCP GW G C+ ++DEC PC HG C++
Sbjct: 769 CELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTN 828
Query: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ-- 1251
++ CTC GYTG +C+ DI++C + C NG +C +SC C F G C +
Sbjct: 829 LAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV 888
Query: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
S CG G CT+ C C PG+ G CE+D+ +C+ C NGG
Sbjct: 889 DECLSNPCG----------PGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGT 938
Query: 1312 CQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
C D +N F CLC + G C+ + AD +S
Sbjct: 939 CVDGVNSFSCLCRPGYTGAHCQHE-ADPCLS 968
Score = 162 bits (409), Expect = 3e-39
Identities = 74/186 (39%), Positives = 97/186 (52%), Gaps = 8/186 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
L ++ C S PC +G C D Y C C G+ G C+ N+D+C +PC HG C D +A+
Sbjct: 506 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIAS 565
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
+ C C PGYTG CE +D C+S C +G C+ + Y C C TG C +
Sbjct: 566 FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVN--IDD 623
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
N T C +G N C+C+PGFTG C +I+ECAS PC GG C D N
Sbjct: 624 CASNPCTFGVCRDGIN------RYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGEN 677
Query: 1318 KFQCLC 1323
F+CLC
Sbjct: 678 GFRCLC 683
Score = 161 bits (407), Expect = 5e-39
Identities = 71/200 (35%), Positives = 112/200 (56%), Gaps = 10/200 (5%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
+ ++ C S+PC++GG C+D + + C+CP G+SG C+L++DEC S PC +G C D+
Sbjct: 468 VDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPD 527
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Y C C G+ G C+ ++D+C C +G C+ +SC C +TG C
Sbjct: 528 GYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQ---- 582
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
+E + C +GG C + + C C G TG CE +ID+CAS+PC G+C+D +
Sbjct: 583 ---VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGI 638
Query: 1317 NKFQCLCDVAFAGERCEVDL 1336
N++ C+C F G C V++
Sbjct: 639 NRYDCVCQPGFTGPLCNVEI 658
Score = 158 bits (400), Expect = 3e-38
Identities = 71/191 (37%), Positives = 100/191 (52%), Gaps = 7/191 (3%)
Query: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA--AYHCTCEP 1204
PC HGG C + S+ C CP G++G CE C +PC +G + Y C C P
Sbjct: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP 226
Query: 1205 GYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKT 1264
G+ G NCEV++D+C H+C NG TC+ N Y+C C +TG+FC + + N
Sbjct: 227 GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN--- 283
Query: 1265 NLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCD 1324
C+NGG C C+C G+TGE C ++ID+CA+ C +G C D + F C C
Sbjct: 284 --ACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 341
Query: 1325 VAFAGERCEVD 1335
+ G C +D
Sbjct: 342 MGKTGLLCHLD 352
Score = 157 bits (397), Expect = 7e-38
Identities = 74/199 (37%), Positives = 104/199 (52%), Gaps = 13/199 (6%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYH--- 1199
C + C HG C D +S++C+CP+G +G C L+ D C SNPC D
Sbjct: 318 CATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAI 376
Query: 1200 CTCEPGYTGVNCEVDIDNCQ--SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
CTC PG+TG C+ D+D C ++ C + C++ + C C +TG C
Sbjct: 377 CTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDV---- 432
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
NE + C N C + + C+C GFTG +CE DIDEC S PCVNGG+C+D +N
Sbjct: 433 ---NECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVN 489
Query: 1318 KFQCLCDVAFAGERCEVDL 1336
F C C F+G C++D+
Sbjct: 490 GFSCTCPSGFSGSTCQLDV 508
Score = 150 bits (378), Expect = 1e-35
Identities = 77/206 (37%), Positives = 98/206 (47%), Gaps = 10/206 (4%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAA 1197
Q+ V C GG C D SS++C CP G +G HCE +D C + PC H G C +
Sbjct: 1046 QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Y C C PGY G NCE D+D C S C +G +CI Y C C G C +
Sbjct: 1106 YMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLC---EINED 1162
Query: 1258 VCGNE---KTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPC---VNGGL 1311
CG + C + G C + +C C PG+TG CE DI+EC S C
Sbjct: 1163 DCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDC 1222
Query: 1312 CQDLLNKFQCLCDVAFAGERCEVDLA 1337
QD F+CLC F+G RC+ L+
Sbjct: 1223 LQDPGGGFRCLCHAGFSGPRCQTVLS 1248
Score = 148 bits (374), Expect = 3e-35
Identities = 75/211 (35%), Positives = 96/211 (45%), Gaps = 12/211 (5%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
L + C S PC GG C +HC+CP G G+ CEL + C NPC HG +
Sbjct: 733 LARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPG 791
Query: 1198 YH--CTCEPGYTGVNCEVDIDNCQSHQ-CANGATCISHTNGYSCLCFGNFTGKFCRQSRL 1254
C+C G+ G C+ D+D C C C + +SC C G +TG C Q
Sbjct: 792 QLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI- 850
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
N+ C NGG+C + C C PGF G C +D+DEC S+PC G C D
Sbjct: 851 ------NDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTD 903
Query: 1315 LLNKFQCLCDVAFAGERCEVDLADDLISDIF 1345
+ F C C + G CE DL D S F
Sbjct: 904 HVASFTCTCPPGYGGFHCEQDLPDCSPSSCF 934
Score = 147 bits (372), Expect = 5e-35
Identities = 75/238 (31%), Positives = 104/238 (43%), Gaps = 44/238 (18%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
C+ + C +GG C D +S+ C C G++G HC+ D C S PC+HG CS + CT
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCT 987
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST---- 1257
C +TG C+ +D C C NG C+ G CLC ++G+ C LP
Sbjct: 988 CLESFTGPQCQTLVDWCSRQPCQNGGRCVQ--TGAYCLCPPGWSGRLCDIRSLPCREAAA 1045
Query: 1258 -------------------------VCGNEKTNL------------TCYNGGNCTEFQTE 1280
VC +T C +GG C +
Sbjct: 1046 QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Query: 1281 LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
C C PG+ G+ CE D+DECAS PC +GG C DL+ ++ C C G CE++ D
Sbjct: 1106 YMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDD 1163
Score = 145 bits (367), Expect = 2e-34
Identities = 78/236 (33%), Positives = 114/236 (48%), Gaps = 38/236 (16%)
Query: 1143 CNSNPCLHGGNCEDIYS-SYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHC 1200
C +PC +GG C +Y C+C G+ G++CE+N+D+C + C++G C D V Y+C
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
Query: 1201 TCEPGYTGVNCEVDIDNCQ--SHQCANGATCISHTNGYSCLCFGNFTGKFCRQS------ 1252
C P +TG C D+D CQ + C NG TC + G+SC+C +TG+ C Q+
Sbjct: 261 QCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT 320
Query: 1253 -----------RLPSTVCGNE--KTNLTCYNGGNCTE-------------FQTELKCMCR 1286
R+ S C KT L C+ C C C
Sbjct: 321 AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCP 380
Query: 1287 PGFTGEWCEKDIDECA--SDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
PGFTG C++D+DEC+ ++PC + G C + F C C + G RCE D+ + L
Sbjct: 381 PGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
Score = 142 bits (357), Expect = 3e-33
Identities = 76/240 (31%), Positives = 103/240 (42%), Gaps = 35/240 (14%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
+++N C S+PC GG+C D + + C CP G C C PC HG C D
Sbjct: 656 VEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGG 715
Query: 1198 YHCTCEPGYTGVNCEVDI--DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR----- 1250
+ C CEPG++G C + D C+S C G TC S G+ C C G+ C
Sbjct: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC 775
Query: 1251 --------------QSRLPSTVCGNEKTNLTCYNG-------------GNCTEFQTELKC 1283
+LP C C G CT C
Sbjct: 776 TPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC 835
Query: 1284 MCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLISD 1343
C G+TG C++DI++C +PC+NGG CQD + F C C FAG RC D+ D+ +S+
Sbjct: 836 TCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV-DECLSN 894
Score = 140 bits (352), Expect = 1e-32
Identities = 70/208 (33%), Positives = 99/208 (47%), Gaps = 16/208 (7%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIY----SSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NC 1191
C + C+S PC G C+ + + C CP G+ G C L D C S+PC HG C
Sbjct: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARC 134
Query: 1192 S-DRVAAYHCTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFTGKFC 1249
S + C+C PGY G +C D+D C+ C +G TC++ + C C +TG C
Sbjct: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Query: 1250 RQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
+P C NGG C + C C PGF G+ CE ++D+C C+N
Sbjct: 195 ENPAVPCAPS-------PCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN 247
Query: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
GG C D +N + C C + G+ C D+
Sbjct: 248 GGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
Score = 137 bits (345), Expect = 7e-32
Identities = 71/210 (33%), Positives = 99/210 (47%), Gaps = 21/210 (10%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAA 1197
+++ C + PC HGG C Y C C G++G +CE ++DEC S PC H G+C D VA
Sbjct: 1084 EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVAR 1143
Query: 1198 YHCTCEPGYTGVNCEVDIDNC-------QSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
Y C+C PG GV CE++ D+C +C + TC+ G+ C C +TG C
Sbjct: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Query: 1251 Q--SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
+ S C T + G +C+C GF+G C+ + C S PC +
Sbjct: 1204 ADINECRSGACHAAHTRDCLQDPGG------GFRCLCHAGFSGPRCQTVLSPCESQPCQH 1257
Query: 1309 GGLCQDLLN-----KFQCLCDVAFAGERCE 1333
GG C+ F C C F G RCE
Sbjct: 1258 GGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
Score = 133 bits (335), Expect = 1e-30
Identities = 85/259 (32%), Positives = 111/259 (42%), Gaps = 59/259 (22%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-------CIH-GNCSDR 1194
C S PC HGG+C D+ + Y CSCP G G CE+N D+C P C+H G C D
Sbjct: 1126 CASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
Query: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQC--ANGATCISHTNG-YSCLCFGNFTGKFCR- 1250
V + CTC PGYTG+ CE DI+ C+S C A+ C+ G + CLC F+G C+
Sbjct: 1186 VGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1245
Query: 1251 --------------QSRLPSTVCGNEKT----------------------NLTCYNGGNC 1274
Q R PS G T L C G C
Sbjct: 1246 VLSPCESQPCQHGGQCR-PSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPC 1304
Query: 1275 TEFQTELKCMCRPGFTGEWCEK--------DIDECASDPCVNGGLCQD--LLNKFQCLCD 1324
+ +C C PG +G C CA+ PC++GG C+ L F+C C
Sbjct: 1305 QQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACA 1364
Query: 1325 VAFAGERCEVDLADDLISD 1343
+ G RCE A +S+
Sbjct: 1365 QGWTGPRCEAPAAAPEVSE 1383
Score = 77.4 bits (189), Expect = 9e-14
Identities = 53/190 (27%), Positives = 73/190 (38%), Gaps = 18/190 (9%)
Query: 1140 LNVCNSNPC--LHGGNC-EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRV 1195
+N C S C H +C +D + C C G+SG C+ + C S PC HG C
Sbjct: 1206 INECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSP 1265
Query: 1196 A-----AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
+ C C + G CE +C+ QC G C G C C +G CR
Sbjct: 1266 GPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1325
Query: 1251 QSRLPSTVCGNEKTNLT---CYNGGNC--TEFQTELKCMCRPGFTGEWCEKD--IDECAS 1303
P + G + C +GG+C +C C G+TG CE E +
Sbjct: 1326 S--FPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSE 1383
Query: 1304 DPCVNGGLCQ 1313
+P CQ
Sbjct: 1384 EPRCPRAACQ 1393
Score = 68.2 bits (165), Expect = 5e-11
Identities = 30/69 (43%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C+S+PC NGGVC R + FSC+CP+ SG C+ +V C +PC +GA+C G+E
Sbjct: 471 DECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530
Query: 948 CIANAVFNG 956
C F G
Sbjct: 531 CRCAEGFEG 539
Score = 58.5 bits (140), Expect = 4e-08
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C S PC N C R F+C C A +G CE ++ C SPC +G C+ + GF
Sbjct: 433 NECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492
Query: 948 CIANAVFNGQSGQI 961
C + F+G + Q+
Sbjct: 493 CTCPSGFSGSTCQL 506
Score = 55.5 bits (132), Expect = 4e-07
Identities = 21/52 (40%), Positives = 30/52 (57%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQ 940
++C+S PC GG C S F C+CP G+ CE + C +PC HG +C+
Sbjct: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 787
Score = 53.5 bits (127), Expect = 1e-06
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C+S PC +GG C D + C CP+ T+G CE + C +PC G C+ + ++
Sbjct: 584 DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYD 642
Query: 948 CIANAVFNG 956
C+ F G
Sbjct: 643 CVCQPGFTG 651
Score = 51.2 bits (121), Expect = 7e-06
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECI 949
C S PC +GGVC + F C+C +G C+ V WC PC +G +C V G C+
Sbjct: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCL 1023
Query: 950 ANAVFNGQ 957
++G+
Sbjct: 1024 CPPGWSGR 1031
Score = 50.4 bits (119), Expect = 1e-05
Identities = 26/73 (35%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSC-PALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECI 949
C + C NGG C + FSC C P T E C PC HG C GF C
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCT 987
Query: 950 ANAVFNGQSGQIL 962
F G Q L
Sbjct: 988 CLESFTGPQCQTL 1000
Score = 49.3 bits (116), Expect = 3e-05
Identities = 30/83 (36%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 881 VTQGCAGDNSCKSNPCHNGGVCHSR----WDDFSCSCPALTSGKACEEVQWCGFSPCPHG 936
V + C ++ C S PC GVC S FSC CP G C C SPC HG
Sbjct: 72 VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHG 131
Query: 937 AQCQPVLQG-FECIANAVFNGQS 958
A+C G F C + G+S
Sbjct: 132 ARCSVGPDGRFLCSCPPGYQGRS 154
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 15/108 (13%)
Query: 866 PNPTNNASLNPVLVNVTQGCA------GDN------SCKSNPCHNGGVCHSRWDDFSCSC 913
P+P N ++T CA G N C + C NGG C + ++C C
Sbjct: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
Query: 914 PALTSGKAC-EEVQWCGFSP--CPHGAQCQPVLQGFECIANAVFNGQS 958
P +G+ C E+V C P C +G C L G C+ + G+S
Sbjct: 263 PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES 310
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/71 (35%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSC-PALTSGKACEEVQWCGFSPCPHG----------A 937
N C NPC NGG C FSCSC P + +V C +PC G
Sbjct: 851 NDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTC 910
Query: 938 QCQPVLQGFEC 948
C P GF C
Sbjct: 911 TCPPGYGGFHC 921
Score = 46.6 bits (109), Expect = 2e-04
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFEC 948
C + PC +GG C + C C +G CE +V C PC HG C ++ + C
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLC 1146
Score = 46.2 bits (108), Expect = 2e-04
Identities = 29/87 (33%), Positives = 34/87 (39%), Gaps = 14/87 (16%)
Query: 884 GCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP---- 932
G GDN C S PC +GG C + CSCP T G CE CG P
Sbjct: 1113 GYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS 1172
Query: 933 ---CPHGAQCQPVLQGFECIANAVFNG 956
C H C ++ GF C + G
Sbjct: 1173 GPRCLHNGTCVDLVGGFRCTCPPGYTG 1199
Score = 45.8 bits (107), Expect = 3e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 883 QGCAGD-NSCK-SNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQC 939
+ C D + C+ PC +GG C + F C CPA +G CE C SPC +G C
Sbjct: 153 RSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212
Query: 940 -QPVLQGFECIANAVFNGQSGQI 961
Q ++C F GQ+ ++
Sbjct: 213 RQSGDLTYDCACLPGFEGQNCEV 235
Score = 45.8 bits (107), Expect = 3e-04
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 883 QGCAGD-NSCKSNP--CHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQ 938
Q C D + C+ P CHNGG C + SC C +G++C + + C + C HGA
Sbjct: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT 328
Query: 939 CQPVLQGFEC 948
C + F C
Sbjct: 329 CHDRVASFYC 338
Score = 45.4 bits (106), Expect = 4e-04
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKAC-EEVQWC--GFSPCPHGAQC 939
C D++C SNPCH +C + + C+CP +G AC ++V C G +PC H +C
Sbjct: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
Query: 940 QPVLQGFECIANAVFNG 956
F C + G
Sbjct: 409 VNTQGSFLCQCGRGYTG 425
Score = 45.4 bits (106), Expect = 4e-04
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C +PCH+G C FSC+C +G CE +V C PC HG +C ++ +
Sbjct: 547 DDCSPDPCHHGR-CVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
Query: 948 C 948
C
Sbjct: 606 C 606
Score = 45.1 bits (105), Expect = 5e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S PC NG C + D + C C G C+ V C PC HG +C + F
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFS 567
Query: 948 CIANAVFNG 956
C + G
Sbjct: 568 CACAPGYTG 576
Score = 45.1 bits (105), Expect = 5e-04
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C SNPC GVC + + C C +G C E+ C SPC G C GF
Sbjct: 622 DDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFR 680
Query: 948 CI 949
C+
Sbjct: 681 CL 682
Score = 45.1 bits (105), Expect = 5e-04
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
N C S+PC GG C + F C CP + C C PC HG C GF
Sbjct: 659 NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGI-CYDAPGGFR 717
Query: 948 CIANAVFNG 956
C+ ++G
Sbjct: 718 CVCEPGWSG 726
Score = 45.1 bits (105), Expect = 5e-04
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPV 942
CA D + C SNPC G C F+C+CP G CE ++ C S C +G C
Sbjct: 884 CARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDG 942
Query: 943 LQGFECIANAVFNG 956
+ F C+ + G
Sbjct: 943 VNSFSCLCRPGYTG 956
Score = 45.1 bits (105), Expect = 5e-04
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
C GG C C CP +G CE EV C PC HG C+ + G+ C +
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
Query: 955 NGQS 958
NG +
Sbjct: 1115 NGDN 1118
Score = 44.7 bits (104), Expect = 6e-04
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDD-FSCSCPALTSGKAC-EEVQWCGF-SPCPHGAQCQP 941
C+ + C S+PC +G C D F CSCP G++C +V C PC HG C
Sbjct: 117 CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLN 176
Query: 942 VLQGFECIANAVFNG 956
F C A + G
Sbjct: 177 TPGSFRCQCPAGYTG 191
Score = 44.3 bits (103), Expect = 8e-04
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 5/95 (5%)
Query: 867 NPTNNASLNPVLVNVTQGCAGDN----SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
NP N ++ T G + S +NPC + G C + F C C +G C
Sbjct: 369 NPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRC 428
Query: 923 E-EVQWCGFSPCPHGAQCQPVLQGFECIANAVFNG 956
E +V C PC + A C + F CI A F G
Sbjct: 429 ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTG 463
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 891 CKSNPCHNGGVCHSRWDDFS-CSCPALTSGKAC-EEVQWC-GFSPC-PHGAQCQPVLQGF 946
C NPC +GG C S CSCP G C ++V C G +PC PHG C + F
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGI-CTNLAGSF 833
Query: 947 ECIANAVFNGQS 958
C + + G S
Sbjct: 834 SCTCHGGYTGPS 845
Score = 42.7 bits (99), Expect = 0.002
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 895 PCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFECIANAV 953
PC G+C + FSC+C +G +C +++ C +PC +G CQ + F C
Sbjct: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPG 878
Query: 954 FNG 956
F G
Sbjct: 879 FAG 881
Score = 42.0 bits (97), Expect = 0.004
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 11/65 (16%)
Query: 885 CAGD-NSCKSNPCHNGGVCHSR------WDDFSCSCPALTSGKACEEV-QWCGFSPCPHG 936
C D N C+S CH H+R F C C A SG C+ V C PC HG
Sbjct: 1202 CEADINECRSGACH---AAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHG 1258
Query: 937 AQCQP 941
QC+P
Sbjct: 1259 GQCRP 1263
Score = 40.8 bits (94), Expect = 0.009
Identities = 17/51 (33%), Positives = 23/51 (45%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
+ C + C +G CH R F C+CP +G C C +PC A C
Sbjct: 316 DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 366
Score = 40.0 bits (92), Expect = 0.016
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 6/74 (8%)
Query: 891 CKSNPCHNGGVCHSRWDD-----FSCSCPALTSGKACEEV-QWCGFSPCPHGAQCQPVLQ 944
C+S PC +GG C F+C C G CE V + C CP G CQ +
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
Query: 945 GFECIANAVFNGQS 958
G C +G S
Sbjct: 1310 GPRCACPPGLSGPS 1323
Score = 39.3 bits (90), Expect = 0.027
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ PC+ GRC+N S+ C C R Y GP C
Sbjct: 399 ANPCEHLGRCVNTQGSFLCQCGRGYTGPRC 428
Score = 38.1 bits (87), Expect = 0.060
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ----GFECIA 950
C + G C F C+CP +G CE ++ C C H A + LQ GF C+
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGGFRCLC 1234
Query: 951 NAVFNG 956
+A F+G
Sbjct: 1235 HAGFSG 1240
Score = 37.7 bits (86), Expect = 0.078
Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 5/39 (12%)
Query: 676 CESQPCQSRGRC-----INLWLSYQCDCHRPYEGPNCLR 709
CESQPCQ G+C L++ C C +P+ GP C R
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCER 1288
Score = 37.4 bits (85), Expect = 0.10
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV---QWCGFSPCPHGAQCQPVLQGFE 947
C PC +G +C+ F C C SG C + C PC G C GF
Sbjct: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFH 757
Query: 948 CIANAVFNGQSGQIL 962
C G+ ++L
Sbjct: 758 CTCPPGVQGRQCELL 772
Score = 37.0 bits (84), Expect = 0.13
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C SQPC+ G+C++L Y C C G NC
Sbjct: 584 DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 617
Score = 37.0 bits (84), Expect = 0.13
Identities = 14/28 (50%), Positives = 16/28 (57%)
Query: 680 PCQSRGRCINLWLSYQCDCHRPYEGPNC 707
PC G C NL S+ C CH Y GP+C
Sbjct: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSC 846
Score = 37.0 bits (84), Expect = 0.13
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C +QPCQ G C Y C+C Y G NC
Sbjct: 1086 DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
Score = 35.8 bits (81), Expect = 0.30
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 673 KDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+D CESQPC++ G C + + + C C +G C
Sbjct: 735 RDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC 769
Score = 35.4 bits (80), Expect = 0.39
Identities = 28/96 (29%), Positives = 37/96 (38%), Gaps = 5/96 (5%)
Query: 866 PNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWD-DFSCSCPALTSGKACEE 924
P P +L +L+ G A +PC NGG C + +C CP G+ C+
Sbjct: 19 PPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQL 78
Query: 925 VQWCGFSPCPHGAQCQ-PVLQG---FECIANAVFNG 956
C PC CQ V+ G F C F G
Sbjct: 79 EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRG 114
Score = 35.0 bits (79), Expect = 0.51
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDC 698
D C SQPCQ G CI+L Y C C
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSC 1148
Score = 35.0 bits (79), Expect = 0.51
Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 9/61 (14%)
Query: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW---------CGFSPCPHGAQCQ 940
SC+ C G C C+CP SG +C C +PC HG C+
Sbjct: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351
Query: 941 P 941
P
Sbjct: 1352 P 1352
Score = 34.3 bits (77), Expect = 0.87
Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 670 CVRKDWCESQPCQSRGRCINLWLS----YQCDCHRPYEGPNC 707
C +D C S PC RG C + ++ + C C R + GP+C
Sbjct: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
Score = 33.9 bits (76), Expect = 1.1
Identities = 13/36 (36%), Positives = 20/36 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLR 709
D C S PC++ +C++ Y+C C +EG C R
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR 544
Score = 33.9 bits (76), Expect = 1.1
Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
DWC QPCQ+ GRC+ C C + G C
Sbjct: 1002 DWCSRQPCQNGGRCVQ--TGAYCLCPPGWSGRLC 1033
Score = 33.5 bits (75), Expect = 1.5
Identities = 12/29 (41%), Positives = 17/29 (58%)
Query: 679 QPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+PC+ G C+N S++C C Y GP C
Sbjct: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Score = 32.3 bits (72), Expect = 3.3
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
C+ PC + G C + S+ C C + GP C R+
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD 887
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 338 bits (867), Expect = 2e-92
Identities = 170/505 (33%), Positives = 250/505 (49%), Gaps = 87/505 (17%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSC-SDTANNLDKDCDNMKDPCFSNPCQGSATC 85
C ++ C+ N+C++NSTCKD C C SD N C+ + C NPC+ ++TC
Sbjct: 730 CEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF---CEQESNECKMNPCKNNSTC 786
Query: 86 VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP--VCICPAGYAGR 143
+ +S+ C+C G++G C I C + C +GG+CH+ I VC+CP Y G+
Sbjct: 787 TDL--YKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQ 844
Query: 144 FC-----------------------------------------EIDHDECASSPCQNGAV 162
FC EID +C CQ+
Sbjct: 845 FCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGD 904
Query: 163 CQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222
C+D ++ + C C PG+ G C++E++EC+S+PCKN TC++ R+ C C Y G CE
Sbjct: 905 CEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCE 964
Query: 223 LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGEN 282
L++++C PCL+ C Y C CAPG+ G +CE+N DEC S+PCLH G+C+DG N
Sbjct: 965 LDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGIN 1024
Query: 283 RYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNE 342
Y+C+C SGF GTHCET C S PC + C + ++ Y C C T QC+I +N+
Sbjct: 1025 HYTCDCK-SGFFGTHCETNANDCLSNPC-LHGRCTELINEYPCSCDADGTSTQCKIKIND 1082
Query: 343 CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC- 401
C S PC + G C + A G+ CIC G+TG +CE+ ++ C
Sbjct: 1083 CTSIPCMNEGFCQK--------------------SAHGFTCICPRGYTGAYCEKSIDNCA 1122
Query: 402 ----SSNPCQNGGTCENLPGN-YTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTC 456
+S C NGG C + PG+ + C C + G+ C + C+ CL+ C
Sbjct: 1123 EPELNSVICLNGGICVDGPGHTFDCRC------LPGFSGQFCEININECSSSPCLHGADC 1176
Query: 457 IPHFQDGQHGFSCLCPSGYTGSLCE 481
H +G+ C C G++G CE
Sbjct: 1177 EDHI----NGYVCKCQPGWSGHHCE 1197
Score = 296 bits (757), Expect = 1e-79
Identities = 180/561 (32%), Positives = 250/561 (44%), Gaps = 118/561 (21%)
Query: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88
+N T N CQ+ + CKD CSCS + + + C D C N S +
Sbjct: 565 ENTTDDQENECQHEAVCKDEINRPRCSCS--LSYIGRLCVVNVDYCLGNH---SISVHGL 619
Query: 89 PGERSFLCKCP--PGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
S C C Y ICE C SC++G Y C G+ G CE
Sbjct: 620 CLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE 679
Query: 147 IDHDECASSPCQNGAVCQDG--------------IDGYSCFCVPGYQGRHCDLEVDECAS 192
ID DECAS PC+NGA C D +DG+SC C PGY G C+ ++D+C
Sbjct: 680 IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
Query: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAP 252
+ C++ +TC + Y C+C ++ G CE E +EC PC N +TC D +Y C+C
Sbjct: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
Query: 253 GFLGDHCELNTDECASQPCLHGGLCVDG--ENRYSCNCTGSGFTGTHCETLMPLC--WSK 308
G+ G +C +EC S PC++GGLC + ++ C C +TG C LC
Sbjct: 800 GWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPL-YTGQFCHQRYNLCDLLHN 858
Query: 309 PCHNNAT---------------------------------------CEDSVDNYTCHCWP 329
PC NN+T CED V+N+ C C P
Sbjct: 859 PCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRP 918
Query: 330 GYTGAQCEIDLNECNSNPCQSNGECVELSS------EKQYG-----------RITG-LPS 371
G++G+ CEI++NEC+S PC++NG CV+L++ E +Y +I+ L
Sbjct: 919 GFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE 978
Query: 372 SFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPF------ 425
+ GY C+C PG+TGI+CE +++EC S PC + G C + +YTC C
Sbjct: 979 ENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTH 1038
Query: 426 ------DNLSRTFYGGR-------------------DCSDILLGCTHQQCLNNGTCIPHF 460
D LS GR C + CT C+N G C
Sbjct: 1039 CETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFC---- 1094
Query: 461 QDGQHGFSCLCPSGYTGSLCE 481
Q HGF+C+CP GYTG+ CE
Sbjct: 1095 QKSAHGFTCICPRGYTGAYCE 1115
Score = 244 bits (623), Expect = 4e-64
Identities = 137/423 (32%), Positives = 193/423 (45%), Gaps = 77/423 (18%)
Query: 26 FCNKNNTRC--LSNSCQNNSTCKDFSKDND-CSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
FC++ C L N C+NNSTC N C C + K+C+ C CQ
Sbjct: 845 FCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEG--KNCEIDVKDCLFLSCQDY 902
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
C + +F C C PG+SG++CE I C C++ G C C C Y G
Sbjct: 903 GDCEDMVN--NFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHG 960
Query: 143 RFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCL 202
FCE+D ++C SPC + C DGY+C C PGY G +C++ +DEC S+PC ++ C+
Sbjct: 961 PFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCI 1020
Query: 203 NEIGRYTCICPHNYSGVNCE-------------------------------------LEI 225
+ I YTC C + G +CE ++I
Sbjct: 1021 DGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKI 1080
Query: 226 DECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECA-----SQPCLHGGLCVDG 280
++C S PC+N CQ + + C C G+ G +CE + D CA S CL+GG+CVDG
Sbjct: 1081 NDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDG 1140
Query: 281 ENR-YSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339
+ C C GF+G CE + C S PC + A CED ++ Y C C PG++G CE +
Sbjct: 1141 PGHTFDCRCL-PGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENE 1199
Query: 340 LNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF----TGIHCE 395
L EC N C EL E + G C+C PGF G+ C
Sbjct: 1200 L-ECIPNSCVH-----ELCMENE----------------PGSTCLCTPGFMTCSIGLLCG 1237
Query: 396 EDV 398
+++
Sbjct: 1238 DEI 1240
Score = 178 bits (452), Expect = 3e-44
Identities = 75/200 (37%), Positives = 115/200 (57%), Gaps = 3/200 (1%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
+ L+ C S PCLH G C D + Y C C G+ G HCE N ++C SNPC+HG C++ +
Sbjct: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINE 1062
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Y C+C+ T C++ I++C S C N C +G++C+C +TG +C +S
Sbjct: 1063 YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKS--IDN 1120
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTE-LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
E ++ C NGG C + C C PGF+G++CE +I+EC+S PC++G C+D +
Sbjct: 1121 CAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHI 1180
Query: 1317 NKFQCLCDVAFAGERCEVDL 1336
N + C C ++G CE +L
Sbjct: 1181 NGYVCKCQPGWSGHHCENEL 1200
Score = 164 bits (414), Expect = 7e-40
Identities = 81/231 (35%), Positives = 111/231 (48%), Gaps = 37/231 (16%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
C N C H C+D++ SY C C W G CE +EC NPC + + C+D +Y C
Sbjct: 737 CILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCE 796
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHT--NGYSCLCFGNFTGKFCRQSR----LP 1255
C G+TG NC +I+ C S C NG C T + CLC +TG+FC Q L
Sbjct: 797 CTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLL 856
Query: 1256 STVCGNEKTNL------------------------------TCYNGGNCTEFQTELKCMC 1285
C N T L +C + G+C + +C+C
Sbjct: 857 HNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCIC 916
Query: 1286 RPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
RPGF+G CE +I+EC+S+PC N G C DL N+F C C+ + G CE+D+
Sbjct: 917 RPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDV 967
Score = 158 bits (400), Expect = 3e-38
Identities = 73/220 (33%), Positives = 113/220 (51%), Gaps = 12/220 (5%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVA 1196
+++N C+S PC + G C D+ + + C+C + G CEL++++C +PC+ NC R
Sbjct: 927 IEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD 986
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Y+C C PGYTG+NCE+++D C S C + CI N Y+C C F G C +
Sbjct: 987 GYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETN---- 1042
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
N+ + C + G CTE E C C T C+ I++C S PC+N G CQ
Sbjct: 1043 ---ANDCLSNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSA 1098
Query: 1317 NKFQCLCDVAFAGERCEVDL---ADDLISDIFTTIGSVTV 1353
+ F C+C + G CE + A+ ++ + G + V
Sbjct: 1099 HGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICV 1138
Score = 151 bits (382), Expect = 4e-36
Identities = 84/269 (31%), Positives = 124/269 (46%), Gaps = 35/269 (13%)
Query: 1081 YVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQL 1140
Y+G + N+ G S I + G+ L+ N + + E +I T
Sbjct: 596 YIGRLCVVNVDYCLGNHS-ISVHGLCLALSHNCNCSGLQRYERNICEIDTED-------- 646
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDR----- 1194
C S C +G + + C G+ G CE++IDEC S+PC +G C D+
Sbjct: 647 --CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYF 704
Query: 1195 ---------VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFT 1245
V + C C PGY G+ CE DID+C + C + +TC Y C+C ++
Sbjct: 705 CQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWE 764
Query: 1246 GKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP 1305
G FC Q NE C N CT+ +C C G+TG+ C ++I+EC SDP
Sbjct: 765 GNFCEQE-------SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP 817
Query: 1306 CVNGGLCQD--LLNKFQCLCDVAFAGERC 1332
C+NGGLC + + +F CLC + G+ C
Sbjct: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFC 846
Score = 146 bits (369), Expect = 1e-34
Identities = 84/266 (31%), Positives = 117/266 (43%), Gaps = 27/266 (10%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C N CLS C ++ C D C C + C+ + C SNPC C
Sbjct: 1001 CEINLDECLSEPCLHDGVCIDGINHYTCDCK--SGFFGTHCETNANDCLSNPCL-HGRCT 1057
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
E + C C + T C+ I C C + G C + CICP GY G +CE
Sbjct: 1058 ELINE--YPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCE 1115
Query: 147 IDHDECA-----SSPCQNGAVCQDGIDG-YSCFCVPGYQGRHCDLEVDECASDPCKNEAT 200
D CA S C NG +C DG + C C+PG+ G+ C++ ++EC+S PC + A
Sbjct: 1116 KSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGAD 1175
Query: 201 CLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
C + I Y C C +SG +CE E+ EC C++ ++ G+ C C PGF+
Sbjct: 1176 CEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHELCMENEPGS-TCLCTPGFM----- 1228
Query: 261 LNTDECASQPCLHGGLCVDGENRYSC 286
C G LC D R +C
Sbjct: 1229 ---------TCSIGLLCGDEIRRITC 1245
Score = 137 bits (344), Expect = 9e-32
Identities = 122/503 (24%), Positives = 191/503 (37%), Gaps = 51/503 (10%)
Query: 14 LSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTC--KDFSKDNDCSCSDTANNLDKDCDNMK 71
L L + +K FC ++ + S C + C + +SK C C + K C +
Sbjct: 161 LGLRLNVTVKQQFCQESLS---SEFCSGHGKCLSEAWSKTYSCHCQPPFSG--KYCQEL- 214
Query: 72 DPCFSNPCQGSATCVNTP---GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQD 128
D C PC+ + +C+N E+++ C C P ++G C IG C + C HG +
Sbjct: 215 DACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNIT 274
Query: 129 PIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD 188
+C C ++G FCE+ C S +C + Y+ C G ++ + +V
Sbjct: 275 SNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVS 334
Query: 189 ECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
E + PC+N C+ CIC ++ + C+ C S P N ATC+ Y C
Sbjct: 335 EFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPC 394
Query: 249 DCAPGFLGDHCELNTDEC--ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETL--MPL 304
C GF +CE D C S CL+ C + R+ C G T C L + L
Sbjct: 395 SCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCI-PGCTKNPCWFLKNVYL 453
Query: 305 CWSKPCHNNAT----CEDSVDNYTCHCWP-GYTG-----------------AQCEIDLNE 342
C+ T C+D + W G+ G A C D
Sbjct: 454 IHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATY 513
Query: 343 CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS 402
N +P +N C + G S S ++ Y +C + G E+ +
Sbjct: 514 VN-DPEDNNSSCWFPHEGTKEICANGC-SCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQ 571
Query: 403 SNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLN-NGTCIPHFQ 461
N CQ+ C++ C C Y GR C + C ++ +G C+
Sbjct: 572 ENECQHEAVCKDEINRPRCSCSLS------YIGRLCVVNVDYCLGNHSISVHGLCLAL-- 623
Query: 462 DGQHGFSCLCPSGYTGSLCEIAT 484
H +C Y ++CEI T
Sbjct: 624 --SHNCNCSGLQRYERNICEIDT 644
Score = 132 bits (332), Expect = 2e-30
Identities = 151/652 (23%), Positives = 241/652 (36%), Gaps = 117/652 (17%)
Query: 134 CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDG-----YSCFCVPGYQGRHCDLEVD 188
C C ++G++C+ + D C+ PC+N C + + Y C C P + G++C +
Sbjct: 200 CHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIG 258
Query: 189 ECASDPCKNEATCLNEIGR-YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
+C C + C N + C C +SG CE+ C S C ++ AY
Sbjct: 259 QCQPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYT 317
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
+C G + E + E + PC +G C+ N C C+ FT C+++ C S
Sbjct: 318 YECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI-FTDLLCKSIQTSCES 376
Query: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECN--SNPCQSNGECVELSSEKQYGR 365
P NNATC+ +Y C C G+T CE ++ C S C + C + +Y
Sbjct: 377 FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVC 436
Query: 366 ITG--------LPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQ---------- 407
I G L + + H+ ++C C F GI C++ P Q
Sbjct: 437 IPGCTKNPCWFLKNVYLIHQ---HLCYCGVTFHGI-CQD------KGPAQFEYVWQLGFA 486
Query: 408 --NGGTCENLPGNY---TCHC---------PFDNLSRTFYGGRDCSDILLGCTHQQCLNN 453
G C+ + Y +C P DN S ++ +I C N
Sbjct: 487 GSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEI--------CANG 538
Query: 454 GTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTKGSVCNIALR 513
+C+ +D Q + LC + G++ TT E + +VC +
Sbjct: 539 CSCLSE-EDSQE-YRYLCFLRWAGNMYLENTTDDQENE----------CQHEAVCKDEIN 586
Query: 514 FQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNTSDGEWHFVEVI 573
+ L R V ++ G +S+ + L +SHN + E
Sbjct: 587 RPRC---SCSLSYIGRLCVVNVDYCLGNHSISVH-----GLCLALSHNCNCSGLQRYERN 638
Query: 574 FAEAVTLTLIDDSCKE-------------KCIAKAP-TPLESDQSICAFQNSFLGGLPVG 619
E T SCK KC+ T E D CA G +
Sbjct: 639 ICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCID 698
Query: 620 MTSNGVA-------LLNFYNMPSTPSFVG--CLQDIKIDWNHITLENISSGSSLNVKAGC 670
N +++ ++ P +VG C QDI D E+ S+ L++ C
Sbjct: 699 QPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDID-DCILNACEHNSTCKDLHLSYQC 757
Query: 671 V-RKDW-----------CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
V DW C+ PC++ C +L+ SY+C+C + G NC E
Sbjct: 758 VCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEE 809
Score = 124 bits (310), Expect = 8e-28
Identities = 128/558 (22%), Positives = 195/558 (34%), Gaps = 149/558 (26%)
Query: 853 QDVRLNNQNLEFFPNPTNNASLNPVLVNVT------------------QGCAGD-NSCKS 893
Q V L++ F +N +NP N T Q C+ + N C S
Sbjct: 756 QCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDS 815
Query: 894 NPCHNGGVCHSRW--DDFSCSCPALTSGKACEE--------------------------- 924
+PC NGG+CH F C CP L +G+ C +
Sbjct: 816 DPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQH 875
Query: 925 ---------------VQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFR----- 964
V+ C F C C+ ++ F CI F+G +I
Sbjct: 876 CICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSE 935
Query: 965 --SNGNITRELTNITFGFRTRDANVIILHAEKEPE----FLNISIQDSRLFFQLQSGNSF 1018
N +LTN F EPE F + + ++ L N
Sbjct: 936 PCKNNGTCVDLTNRFF-------------CNCEPEYHGPFCELDVNKCKISPCLDEENCV 982
Query: 1019 YMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLN-FLKDN 1077
Y + T +++ + LS+ P + + +N + D
Sbjct: 983 YRTDGYNCLCAPGYTGINCEINLDECLSE------------PCLHDGVCIDGINHYTCDC 1030
Query: 1078 TDIYVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGC 1137
+ G N CLS +HG + E + T C
Sbjct: 1031 KSGFFGTHCETN---ANDCLSN-----------PCLHGRCTELINEYPCSCDADGTSTQC 1076
Query: 1138 -LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECF-----SNPCIHGN- 1190
+++N C S PC++ G C+ + C CP G++G +CE +ID C S C++G
Sbjct: 1077 KIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGI 1136
Query: 1191 CSDRVA-AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFC 1249
C D + C C PG++G CE++I+ C S C +GA C H NGY C C ++G C
Sbjct: 1137 CVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHC 1196
Query: 1250 RQSR--LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCV 1307
+P++ C +E C E + C+C PGF C
Sbjct: 1197 ENELECIPNS-CVHEL----------CMENEPGSTCLCTPGFM--------------TCS 1231
Query: 1308 NGGLCQDLLNKFQCLCDV 1325
G LC D + + CL +
Sbjct: 1232 IGLLCGDEIRRITCLTPI 1249
Score = 121 bits (304), Expect = 4e-27
Identities = 66/245 (26%), Positives = 97/245 (39%), Gaps = 61/245 (24%)
Query: 1146 NPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI--HGNCSDRVAAYHCT-- 1201
N C H C+D + CSC L + G+ C +N+D C N I HG C +C+
Sbjct: 573 NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGL 632
Query: 1202 ------------------------------------CEPGYTGVNCEVDIDNCQSHQCAN 1225
C PG+ G CE+DID C SH C N
Sbjct: 633 QRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKN 692
Query: 1226 GATCISH--------------TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNG 1271
GATCI +G+SCLC + G C Q + + C +
Sbjct: 693 GATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQD-IDDCILN------ACEHN 745
Query: 1272 GNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGER 1331
C + +C+C + G +CE++ +EC +PC N C DL ++C C + G+
Sbjct: 746 STCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQN 805
Query: 1332 CEVDL 1336
C ++
Sbjct: 806 CSEEI 810
Score = 116 bits (291), Expect = 1e-25
Identities = 198/894 (22%), Positives = 313/894 (35%), Gaps = 173/894 (19%)
Query: 445 CTHQQCLNNGTCIPHF-QDGQHGFSCLCPSGYTGSLCEIATTL---SFEGDGFL---WVK 497
C C N GTC F G F C CP +TG CE L SF G+ +L ++K
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPSFNGNSYLELPFLK 2162
Query: 498 SGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDV---FVKLELLSGYIHLSIQVNNQSKV 554
I L +T +L+ + + F+ L L+ G + N +
Sbjct: 2163 FVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNI 2222
Query: 555 LLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLE------SDQSICAF 608
L +S N S F + + C + A P++ S S F
Sbjct: 2223 LT-VSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYF 2281
Query: 609 QNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHI-TLENISSGSSLNVK 667
++ FLG +P + + A F GC+ D++++ ++ G ++
Sbjct: 2282 ESMFLGHIPANVQIHKKA-------GPVYGFRGCILDLQVNNKEFFIIDEARHGKNIE-- 2332
Query: 668 AGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPN--------------------- 706
C WC C++ G CI+ + C+C R Y G
Sbjct: 2333 -NC-HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKS 2390
Query: 707 -----CLREY-------------VAGRFGQDDSTGYVIFTLDESYGDTISLSMFVRTLQP 748
CL Y RF D+ GY F D F Q
Sbjct: 2391 GTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQL 2450
Query: 749 SGLLLALENSTYQYIRVWLERGR-------LAMLTPNSPKLVVKFVLNDGNVHLISLKIK 801
+ AL+N+ + ++G LA+ N +V + L G + S++ +
Sbjct: 2451 ANNHSALQNNLIFFTG---QKGHGLNGDDFLAVGLLNG-SVVYSYNLGSG---IASIRSE 2503
Query: 802 PYKIELYQSSQNLGFISASTWK----------IEKGDVI--------YIGGLPDKQETEL 843
P + L + +LG W I G ++ Y+GG + L
Sbjct: 2504 PLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLL 2563
Query: 844 NGGF-----FKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHN 898
G F+GCI +++ + F N +P C + C C N
Sbjct: 2564 PNGADFKNGFQGCIFTLQVRTEKDGHFRG-LGNPEGHPNAGRSVGQCHA-SPCSLMKCGN 2621
Query: 899 GGVCHSRWDDFSCSCPALTSGKACEE-VQWCG--FSP---CPHGAQCQPVLQGFECIA-- 950
GG C C+C G C E V C P C GA C + G+ C
Sbjct: 2622 GGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPL 2681
Query: 951 --NAVFNGQSGQIL---FRSN--------GNITRELTNITFGFRTRDANVIILHAEKE-- 995
++ Q+ I FRSN R+ T+I F+ A+ I+ +A +
Sbjct: 2682 GTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLK 2741
Query: 996 ---PEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQ 1052
+FL IS+ +S + + G+ +L ++N TWH + +
Sbjct: 2742 AQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVG-----AEGY 2796
Query: 1053 MEVDNETPFVTSTIATGSLNFLKDNTDIYVGD---------RAIDNIK-GLQGCLSTIEI 1102
+++D VT +T ++ L NTD Y+G AI+N G QGC+ + I
Sbjct: 2797 LDLDGIN--VTEKAST-KMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVII 2853
Query: 1103 GGIYLSYFENVHGFINKPQEEQFLKISTN--SVVTGCLQLNVCNSNPCLHGGNCEDIYSS 1160
QE Q + S V C C N C +GG C ++
Sbjct: 2854 NN----------------QELQLTEFGAKGGSNVGDC-DGTACGYNTCRNGGECTVNGTT 2896
Query: 1161 YHCSCPLGWSGKHCELNIDECFSNPCIHGN--CSDRVAAYHCTCEPGYTGVNCE 1212
+ C C W+G C ++ C +N C+H + D+ +Y C C G+ G CE
Sbjct: 2897 FSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 104 bits (260), Expect = 5e-22
Identities = 65/229 (28%), Positives = 91/229 (39%), Gaps = 40/229 (17%)
Query: 1144 NSNPCLHGGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDR-----V 1195
+S C G C E +Y C C +SGK+C+ +D C PC + G+C ++
Sbjct: 179 SSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKRENWDE 237
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
AY C C P +TG NC I CQ H C +G +N + C C F+G FC S P
Sbjct: 238 QAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVSAKP 297
Query: 1256 ST--------VCGNEKTNLT-----------------------CYNGGNCTEFQTELKCM 1284
+C N + T C NG +C + ++ C+
Sbjct: 298 CVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCI 357
Query: 1285 CRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
C P FT C+ C S P N C+ + C C F + CE
Sbjct: 358 CSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
Score = 101 bits (252), Expect = 4e-21
Identities = 194/894 (21%), Positives = 336/894 (37%), Gaps = 219/894 (24%)
Query: 488 FEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRD-----VFVKLELLSGYI 542
+ GD +L ++ ++ + NI+L FQT LLL+ F++L + +G +
Sbjct: 1888 YYGDSYLEFQNVALNPQN---NISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTL 1944
Query: 543 HLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESD 602
++K F S NT+ V V + TL + + + C A+ T L +
Sbjct: 1945 KYHFYCPGEAK---FKSINTT------VRVDNGQKYTLLIRQEL--DPCNAEL-TILGRN 1992
Query: 603 QSICAFQNSFLGG-LPVGMTSNGVALLNF------YNMP-STPSFVGCLQDIKID-WNHI 653
IC N LG LP S V + F MP +F GC++ I+I+ W
Sbjct: 1993 TQICESINHVLGKPLP---KSGSVFIGGFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSF 2049
Query: 654 ----TLENI------SSGSSLNVKAGCVRKD---------W------------CESQPCQ 682
++N S G L+ A V W C+ C
Sbjct: 2050 IPSKAVKNYHINNCRSQGFMLSPTASFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCH 2109
Query: 683 SRGRCINLWLS-----YQCDCHRPYEGPNCLREYVAGRFGQDDSTG------YVIFTLDE 731
+ G C ++LS +QCDC + G C ++ AG F + ++ F L++
Sbjct: 2110 NGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD--AGLFFPSFNGNSYLELPFLKFVLEK 2167
Query: 732 SYGDTISLSMFVRTLQPSGLLLALE--NSTYQYIRVWLERGRLAML--TPNSPKLVVKFV 787
+ T+++ + ++T +G +L N Q++ ++L GR ++ NS ++
Sbjct: 2168 EHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTV-- 2225
Query: 788 LNDGNVHLISLKIKPYKIELYQSSQNLGFISASTWK------IEKGDV------------ 829
N + + P I + G + ++K D
Sbjct: 2226 --SANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFES 2283
Query: 830 IYIGGLPDKQETELNGG---FFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCA 886
+++G +P + G F+GCI D+++NN+ EFF ++ G
Sbjct: 2284 MFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNK--EFF-----------IIDEARHGKN 2330
Query: 887 GDNS----CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPV 942
+N C + C N G C S ++ C CP L SGK C+ C +PC +GA C P
Sbjct: 2331 IENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPK 2389
Query: 943 LQGFECIANAVFNGQSGQILFRSNGNITRELTNIT--FGFRTRDA----NVIILHAEKEP 996
G + + + G+SG + + NIT+ + T FG+ + A + I H E
Sbjct: 2390 -SGTDIVCLCPY-GRSGPLCTDAI-NITQPRFSGTDAFGYTSFLAYSRISDISFHYEFHL 2446
Query: 997 EFL----NISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSM------TDPLS 1046
+F + ++Q++ +FF Q G+ ++ +N + L ++PL+
Sbjct: 2447 KFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN 2506
Query: 1047 QT-------------SRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVGD--------- 1084
+ W D++ S IA G L L + YVG
Sbjct: 2507 LSLGVHTVHLGKFFQEGWLKVDDHKNK---SIIAPGRLVGLNVFSQFYVGGYSEYTPDLL 2563
Query: 1085 -RAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVC 1143
D G QGC+ T+++ +F + P + + C
Sbjct: 2564 PNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNPEGHPNAGR--------------SVGQC 2609
Query: 1144 NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCE 1203
+++PC ++ +C + G C + + +C C
Sbjct: 2610 HASPC----------------------------SLMKCGNG----GTCIESGTSVYCNCT 2637
Query: 1204 PGYTGVNCEVDIDNCQS-----HQCANGATCISHTNGYSCLCFGNFTGKFCRQS 1252
G+ G C + C H C+ GATCIS +GY+C C TG +C Q+
Sbjct: 2638 TGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQA 2691
Score = 99.8 bits (247), Expect = 2e-20
Identities = 61/213 (28%), Positives = 92/213 (43%), Gaps = 25/213 (11%)
Query: 1148 CLHGGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEP 1204
C +G +C E+ Y C L W+G N + N C H C D + C+C
Sbjct: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSL 594
Query: 1205 GYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEK 1263
Y G C V++D C +H + C++ ++ +C + C + +
Sbjct: 595 SYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICE-------IDTEDC 647
Query: 1264 TNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD--------- 1314
+ +C NG T + C PGF G CE DIDECAS PC NG C D
Sbjct: 648 KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQC 707
Query: 1315 -----LLNKFQCLCDVAFAGERCEVDLADDLIS 1342
+++ F CLC+ + G RCE D+ D +++
Sbjct: 708 VPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILN 740
Score = 94.0 bits (232), Expect = 9e-19
Identities = 58/190 (30%), Positives = 86/190 (45%), Gaps = 22/190 (11%)
Query: 1143 CNSNPCLHGGNCEDIYS-SYHCSCPLGWSGKHCELNIDECFSNPCI------HGNCSDRV 1195
C + C H GNC +I S S+ C C +SG CE++ + PC+ G C +
Sbjct: 260 CQPHVCFH-GNCSNITSNSFICECDEQFSGPFCEVS-----AKPCVSLLFWKRGICPNSS 313
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
+AY C G + N E D+ C NG CI +N C+C FT C+ +
Sbjct: 314 SAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQ-- 371
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--ASDPCVNGGLCQ 1313
T C + N C + + + C C GFT + CEK ID C S C+N C
Sbjct: 372 -TSC----ESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCF 426
Query: 1314 DLLNKFQCLC 1323
+++ +F+ +C
Sbjct: 427 NIIGRFKYVC 436
Score = 79.0 bits (193), Expect = 3e-14
Identities = 211/1007 (20%), Positives = 334/1007 (33%), Gaps = 205/1007 (20%)
Query: 190 CASDPCKNEATC-----LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQD--- 241
C D C N TC + I + C CP +++G CE + + P NG + +
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF--PSFNGNSYLELPF 2160
Query: 242 -----------ALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTG 290
+ Y G N + C Q LH L V+G C
Sbjct: 2161 LKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQ-FLHLFL-VEGRPSVKYGCGN 2218
Query: 291 SGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQS 350
S + ++ + + + NA ++ YT G G C I++ P Q
Sbjct: 2219 S-------QNILTVSANYSINTNAFTPITI-RYTTPV--GSPGVVCMIEMTADGKPPVQK 2268
Query: 351 NGECVELSSEKQYGR--ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE-------- 400
+ +S+ + + +P++ H+ +G V GF G + VN
Sbjct: 2269 KDTEISHASQAYFESMFLGHIPANVQIHKKAGPVY----GFRGCILDLQVNNKEFFIIDE 2324
Query: 401 --------------CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCT 446
C+ + C+N GTC + N C CP Y G+ C C
Sbjct: 2325 ARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECP------RLYSGKLCQ--FASCE 2376
Query: 447 HQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLS---FEG-DGFLWVKSGSVT 502
+ C N TC+P CLCP G +G LC A ++ F G D F + + +
Sbjct: 2377 NNPCGNGATCVP---KSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTDAFGYTSFLAYS 2433
Query: 503 TKGSVC---NIALRFQTVQPMA-----LLLFRS------NRDVFVKLELLSGYIHLSIQV 548
+ L+FQ + L+ F N D F+ + LL+G + S +
Sbjct: 2434 RISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNL 2493
Query: 549 NNQSKVLLFISHNTSDGEWHFVEV--IFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSIC 606
+ + N S G H V + F E L D K K I AP L +
Sbjct: 2494 GSGIASIRSEPLNLSLGV-HTVHLGKFFQEG---WLKVDDHKNKSII-APGRL---VGLN 2545
Query: 607 AFQNSFLGG---LPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKI----DWNHITLENIS 659
F ++GG + NG N F GC+ +++ D + L N
Sbjct: 2546 VFSQFYVGGYSEYTPDLLPNGADFKN--------GFQGCIFTLQVRTEKDGHFRGLGNPE 2597
Query: 660 SGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQD 719
+ G C C + G CI S C+C ++G C E V+ +
Sbjct: 2598 GHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC-TETVSTCDPEH 2656
Query: 720 D-----STGYVIFTLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAM 774
D S G +L Y T + + L + S W+ +
Sbjct: 2657 DPPHHCSRGATCISLPHGY--TCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHV 2714
Query: 775 LTPNSPKLVVKFVLNDGNVHLISLKIKPYK-----IELYQSSQNLGF------------- 816
+L + + DG + + +K I L SS L +
Sbjct: 2715 RKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQ 2774
Query: 817 ---ISASTWKIEKGDVIYIGG--------LPDKQETEL-----NGGFFKGCIQDVRLNNQ 860
I+ STW I K + G + +K T++ N F+ G + + L N
Sbjct: 2775 KVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNP 2834
Query: 861 NLEFFPNPTN-NASLNPVLVNVTQ--------------GCAGDNSCKSNPCHNGGVCHSR 905
+ P + V++N + G +C N C NGG C
Sbjct: 2835 -MAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVN 2893
Query: 906 WDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQ-GFECI--------------- 949
FSC C +G C + C + C H + C P + C+
Sbjct: 2894 GTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTS 2953
Query: 950 -ANAVFNGQSGQILFRSNGNITR-ELTNITFGFRTRDANVII----LHAEKEPEFLNISI 1003
+ A F G S N + + T I+ F T +I + +E +FL I +
Sbjct: 2954 FSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGL 3013
Query: 1004 QDSRLFFQLQSGNSFYMLSLTSLQSVNDGT-----WHEVTLSMTDPL 1045
+ L + G ++ S N+GT WH V + L
Sbjct: 3014 HNQTLKIAVNLGE-----RISVPMSYNNGTFCCNKWHHVVVIQNQTL 3055
Score = 71.6 bits (174), Expect = 5e-12
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 16/193 (8%)
Query: 1152 GNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVN 1210
G C + S+Y CP G S ++ E ++ E PC +G +C C C P +T +
Sbjct: 307 GICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLL 366
Query: 1211 CEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN 1270
C+ +C+S N ATC Y C C FT K C ++ + + ++ C N
Sbjct: 367 CKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKA-----IDHCKLLSINCLN 421
Query: 1271 GGNCTEFQTELKCMCRPGFTGE--WCEKDIDECASDPCVNG----GLCQDL-LNKFQCLC 1323
C K +C PG T W K++ C G G+CQD +F+ +
Sbjct: 422 EEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVW 481
Query: 1324 DVAFA---GERCE 1333
+ FA GE+C+
Sbjct: 482 QLGFAGSEGEKCQ 494
Score = 69.3 bits (168), Expect = 2e-11
Identities = 74/299 (24%), Positives = 121/299 (40%), Gaps = 55/299 (18%)
Query: 1073 FLKDNTDIYV-GDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTN 1131
FL NT I G++A+ I LQ I++G I + E F E + +S
Sbjct: 59 FLGVNTKIDTSGNQAVPQICPLQ-----IQLGDILVISSEPSLQF----PEINLMNVSET 109
Query: 1132 SVVTGCLQLNVCNSNPCLHGGNCEDIYS------------------SYHCSCPLGW---- 1169
S V GC+Q N + L G + +++ S CPLG
Sbjct: 110 SFV-GCVQ-NTTTEDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCPLGLRLNV 167
Query: 1170 --SGKHCELNIDECFSNPCIHGNCSDRV--AAYHCTCEPGYTGVNCEVDIDNCQSHQCAN 1225
+ C+ ++ F + HG C Y C C+P ++G C+ ++D C C N
Sbjct: 168 TVKQQFCQESLSSEFCSG--HGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKN 224
Query: 1226 GATCISHTNG-----YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
+CI+ Y C+C FTGK C S + G + ++ C++G NC+ +
Sbjct: 225 NGSCINKRENWDEQAYECVCHPPFTGKNC------SEIIGQCQPHV-CFHG-NCSNITSN 276
Query: 1281 -LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
C C F+G +CE C S G+C + + + C + + E D+++
Sbjct: 277 SFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSE 335
Score = 67.4 bits (163), Expect = 9e-11
Identities = 60/259 (23%), Positives = 113/259 (43%), Gaps = 27/259 (10%)
Query: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTC 456
D C N C+NGG C ++C C D + G C+ + C + CL+ C
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPD------WAGNTCNQ-SVSCLNNLCLHQSLC 2927
Query: 457 IPHFQDGQHGFSCLCPSGYTGSLCEIATTLS---FEGDGFL-WVKSGSVTTKGSVCNIAL 512
IP D +SCLC G+ G CE T+ S F G+ ++ ++ I+L
Sbjct: 2928 IP---DQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISL 2984
Query: 513 RFQTVQPMALLLF----RSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNT-SDGEW 567
F T + L+++ ++ + F+ + L + + +++ + + V + ++ T +W
Sbjct: 2985 NFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKW 3044
Query: 568 HFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVAL 627
H V VI + + I++S +++ P ++ ++ +LGG G N V
Sbjct: 3045 HHVVVIQNQTLIKAYINNSL---ILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQ 3101
Query: 628 LNFYNMPSTPSFVGCLQDI 646
F +FVG ++D+
Sbjct: 3102 EIF-----KTNFVGKIKDV 3115
Score = 57.4 bits (137), Expect = 1e-07
Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 38/232 (16%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC--FSNPCIHGN-CSDRVAAYH 1199
C S P + C+ Y CSC G++ K+CE ID C S C++ C + + +
Sbjct: 374 CESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFK 433
Query: 1200 CTCEPGYTGVNCEV--DIDNCQSHQCANGATC--ISHTNGYSC------LCFGNFTGKFC 1249
C PG T C ++ H C G T I G + L F G+ C
Sbjct: 434 YVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKC 493
Query: 1250 R-----------------------QSRLPSTVCGNEKTNLTCYNGGNCT--EFQTELKCM 1284
+ + S +E T C NG +C E E + +
Sbjct: 494 QGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYL 553
Query: 1285 CRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
C + G ++ + + C + +C+D +N+ +C C +++ G C V++
Sbjct: 554 CFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNV 605
Score = 56.6 bits (135), Expect = 2e-07
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 66 DCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGIC 125
DCD C N C+ C T +F C+C P ++G C ++ SC N C H +C
Sbjct: 2873 DCDGTA--CGYNTCRNGGEC--TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLC 2927
Query: 126 HQDPIYPV-CICPAGYAGRFCE 146
D + C+C G+ GR+CE
Sbjct: 2928 IPDQSFSYSCLCTLGWVGRYCE 2949
Score = 54.7 bits (130), Expect = 6e-07
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC-QDL 1315
T CG TC NGG CT T C C P + G C + + C ++ C++ LC D
Sbjct: 2877 TACGYN----TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 1316 LNKFQCLCDVAFAGERCE 1333
+ CLC + + G CE
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 10/82 (12%)
Query: 151 ECASSPCQ-----NGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC--ASDP---CKNEAT 200
+C +SPC NG C + C C G++G C V C DP C AT
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 201 CLNEIGRYTCICPHNYSGVNCE 222
C++ YTC CP +G+ CE
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
Score = 50.8 bits (120), Expect = 9e-06
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC--ASDP---CVNGGLCQDLLNKFQ 1320
+ C NGG C E T + C C G+ G +C + + C DP C G C L + +
Sbjct: 2617 MKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYT 2676
Query: 1321 CLCDVAFAGERCEVDLA 1337
C C + G CE L+
Sbjct: 2677 CFCPLGTTGIYCEQALS 2693
Score = 49.3 bits (116), Expect = 3e-05
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 7/100 (7%)
Query: 100 PGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-----EIDHDECAS 154
P ++ + C C +GG C + C C G+ G FC D +
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 155 SPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDP 194
C GA C GY+CFC G G +C+ + SDP
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS--ISDP 2697
Score = 49.3 bits (116), Expect = 3e-05
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 107 CETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-QD 165
C+ T +CG N+C++GG C + C C +AG C C ++ C + ++C D
Sbjct: 2874 CDGT--ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSCLNNLCLHQSLCIPD 2930
Query: 166 GIDGYSCFCVPGYQGRHCD 184
YSC C G+ GR+C+
Sbjct: 2931 QSFSYSCLCTLGWVGRYCE 2949
Score = 48.5 bits (114), Expect = 4e-05
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 40/174 (22%)
Query: 823 KIEKGDVIYIGGLPDKQETELN-----GGFFKGCIQDVRLNNQNL--------------- 862
+I+ GD++ I P Q E+N F GC+Q+ +Q L
Sbjct: 81 QIQLGDILVISSEPSLQFPEINLMNVSETSFVGCVQNTTTEDQLLFGCRLKGMHTVNSKW 140
Query: 863 ------EFFPNPTNNASLNPV--LVNVT---QGCAGDNSCKSNPCHNGGVCHSR-WDD-F 909
F + S P+ +NVT Q C S S C G C S W +
Sbjct: 141 LSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFC--QESLSSEFCSGHGKCLSEAWSKTY 198
Query: 910 SCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVL-----QGFECIANAVFNGQS 958
SC C SGK C+E+ C F PC + C Q +EC+ + F G++
Sbjct: 199 SCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKN 252
Score = 48.5 bits (114), Expect = 4e-05
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 146 EIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCL-NE 204
+ D C + C+NG C +SC C+P + G C+ V C ++ C +++ C+ ++
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 205 IGRYTCICPHNYSGVNCE 222
Y+C+C + G CE
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 48.1 bits (113), Expect = 6e-05
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC--QDGIDGYS 171
C + C++ G C D C CP Y+G+ C+ C ++PC NGA C + G D
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTD-IV 2395
Query: 172 CFCVPGYQGRHC 183
C C G G C
Sbjct: 2396 CLCPYGRSGPLC 2407
Score = 47.8 bits (112), Expect = 8e-05
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 12/91 (13%)
Query: 1210 NCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCY 1269
NC V C H C N TCIS C C ++GK C+ + + CG
Sbjct: 2333 NCHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCG--------- 2381
Query: 1270 NGGNCT-EFQTELKCMCRPGFTGEWCEKDID 1299
NG C + T++ C+C G +G C I+
Sbjct: 2382 NGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 47.4 bits (111), Expect = 1e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
C + C+NN TC +++ C C + K C C +NPC ATCV G
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSG--KLCQFAS--CENNPCGNGATCVPKSG-TD 2393
Query: 94 FLCKCPPGYSGTICETTI 111
+C CP G SG +C I
Sbjct: 2394 IVCLCPYGRSGPLCTDAI 2411
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Query: 184 DLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC-QDA 242
D + C + C+N C ++C C +++G C + C + CL+ + C D
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 243 LGAYFCDCAPGFLGDHCELNT 263
+Y C C G++G +CE T
Sbjct: 2932 SFSYSCLCTLGWVGRYCENKT 2952
Score = 41.6 bits (96), Expect = 0.005
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF 1277
C + C NG C + +SC C ++ G C Q S C N C + C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ----SVSC----LNNLCLHQSLCIPD 2930
Query: 1278 QT-ELKCMCRPGFTGEWCE 1295
Q+ C+C G+ G +CE
Sbjct: 2931 QSFSYSCLCTLGWVGRYCE 2949
Score = 40.0 bits (92), Expect = 0.016
Identities = 24/84 (28%), Positives = 31/84 (36%), Gaps = 10/84 (11%)
Query: 187 VDECASDPCK-----NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQ-----PCLNG 236
V +C + PC N TC+ C C + G C + C + C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 237 ATCQDALGAYFCDCAPGFLGDHCE 260
ATC Y C C G G +CE
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 40.0 bits (92), Expect = 0.016
Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 9/83 (10%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCS-----DTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88
C C N TC + C+C+ CD DP + C ATC++
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP--PHHCSRGATCISL 2671
Query: 89 PGERSFLCKCPPGYSGTICETTI 111
P + C CP G +G CE +
Sbjct: 2672 P--HGYTCFCPLGTTGIYCEQAL 2692
Score = 39.7 bits (91), Expect = 0.021
Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 875 NPVLVNVTQGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP 932
NP V + C D + C N C + C + C C + G CE E C +P
Sbjct: 722 NPGYVGIR--CEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNP 779
Query: 933 CPHGAQCQPVLQGFECIANAVFNGQS 958
C + + C + + + C + + GQ+
Sbjct: 780 CKNNSTCTDLYKSYRCECTSGWTGQN 805
Score = 39.7 bits (91), Expect = 0.021
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S+PC++ G C++L + C+C Y GP C
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFC 963
Score = 39.3 bits (90), Expect = 0.027
Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 15/83 (18%)
Query: 889 NSCKSNPCHNGGVCHSR--------------WDDFSCSCPALTSGKACE-EVQWCGFSPC 933
+ C S+PC NG C + D FSC C G CE ++ C + C
Sbjct: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNAC 742
Query: 934 PHGAQCQPVLQGFECIANAVFNG 956
H + C+ + ++C+ + + G
Sbjct: 743 EHNSTCKDLHLSYQCVCLSDWEG 765
Score = 38.9 bits (89), Expect = 0.035
Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 4/96 (4%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFEC 948
N C S+PC +G C + + C C SG CE C + C H C G C
Sbjct: 1163 NECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVH-ELCMENEPGSTC 1221
Query: 949 IANAVFNGQSGQILFRSNGNITRELTNITFGFRTRD 984
+ F S +L G+ R +T +T F+ D
Sbjct: 1222 LCTPGFMTCSIGLLC---GDEIRRITCLTPIFQRTD 1254
Score = 38.5 bits (88), Expect = 0.046
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 3/66 (4%)
Query: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL-NKFQCLCDVA 1326
C N G C L C C ++G+ C+ C ++PC NG C CLC
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 1327 FAGERC 1332
+G C
Sbjct: 2402 RSGPLC 2407
Score = 38.1 bits (87), Expect = 0.060
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 885 CAGDNSCKSNPCHNGGVC---HSRWDD--FSCSCPALTSGKACEE-VQWCGFSPCPHGAQ 938
C ++C PC N G C WD+ + C C +GK C E + C C HG
Sbjct: 211 CQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNC 270
Query: 939 CQPVLQGFECIANAVFNG 956
F C + F+G
Sbjct: 271 SNITSNSFICECDEQFSG 288
Score = 37.0 bits (84), Expect = 0.13
Identities = 29/104 (27%), Positives = 40/104 (38%), Gaps = 8/104 (7%)
Query: 30 NNTRCLSNSCQNNSTCKDFSKDNDCSC-SDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88
+ T C N+C+N C C C D A N C N C +N C + C+
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGN---TC-NQSVSCLNNLCLHQSLCI-- 2928
Query: 89 PGER-SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIY 131
P + S+ C C G+ G CE + I + DP Y
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNY 2972
Score = 35.8 bits (81), Expect = 0.30
Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQC--QP------ 941
CKS C NG F C G CE ++ C PC +GA C QP
Sbjct: 647 CKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQ 706
Query: 942 ------VLQGFECIANAVFNG 956
V+ GF C+ N + G
Sbjct: 707 CVPPFKVVDGFSCLCNPGYVG 727
Score = 34.3 bits (77), Expect = 0.87
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 5/40 (12%)
Query: 1301 CASDPCVNGGLCQDL-----LNKFQCLCDVAFAGERCEVD 1335
C D C NGG C + + FQC C + F G CE D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 33.9 bits (76), Expect = 1.1
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 114 CGKNSCQHGGICH-----QDPIYPVCICPAGYAGRFCEID 148
C ++ C +GG CH + C CP + GRFCE D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 33.1 bits (74), Expect = 1.9
Identities = 14/37 (37%), Positives = 19/37 (51%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ D C S+PC G CI+ Y CDC + G +C
Sbjct: 1003 INLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
Score = 31.6 bits (70), Expect = 5.6
Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 1/55 (1%)
Query: 895 PCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQGFEC 948
PC NG C +D C C + + C+ +Q C P + A C+ + + C
Sbjct: 340 PCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPC 394
Score = 31.2 bits (69), Expect = 7.3
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPY---EGPNCLRE--YVAGRFGQD 719
D C S PC++ CI+ +Y C C P+ +G +CL YV R QD
Sbjct: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQD 733
Score = 31.2 bits (69), Expect = 7.3
Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
Query: 1268 CYNGGNC-----TEFQTELKCMCRPGFTGEWCEKD 1297
C+NGG C + +C C FTG +CEKD
Sbjct: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 335 bits (859), Expect = 2e-91
Identities = 161/491 (32%), Positives = 239/491 (48%), Gaps = 66/491 (13%)
Query: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDN-DCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
C+K+ C ++ C N TC + D CSC + + +C+ + C S+PC +
Sbjct: 293 CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG--PNCEIAEHACLSDPCHNRGS 350
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
C T F C+C PG++G C T I C N+C HGG C C+CP + G+
Sbjct: 351 CKET--SLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
C++D +EC + PC N C++ I Y C C+PG+ G++CD+ +++C C+N+A+C +
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDL 467
Query: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
+ Y CICP Y+G +CE +IDEC S PCLNG CQ+ + + C C GF G+ C+L+ D
Sbjct: 468 VNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDID 527
Query: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATC-------- 316
C PC +G C + + Y C C + G +C L C + PC +C
Sbjct: 528 YCEPNPCQNGAQCYNRASDYFCKCP-EDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASND 586
Query: 317 --------------------EDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVE 356
S +TC C G+TG C ++N+C SNPC++ G C++
Sbjct: 587 TPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCID 646
Query: 357 LSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLP 416
+ Y CIC G+ G +CE ++N+CS NPC NGGTC +L
Sbjct: 647 --------------------GVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 417 GNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
++ C C + + G+ C C C N GTC D F C+CP G+
Sbjct: 687 NDFYCDC------KNGWKGKTCHSRDSQCDEATCNNGGTCY----DEGDAFKCMCPGGWE 736
Query: 477 GSLCEIATTLS 487
G+ C IA S
Sbjct: 737 GTTCNIARNSS 747
Score = 315 bits (806), Expect = 3e-85
Identities = 165/503 (32%), Positives = 226/503 (44%), Gaps = 63/503 (12%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C CLS+ C N +CK+ S +C CS C D C N C TC
Sbjct: 333 CEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTG--PTCSTNIDDCSPNNCSHGGTCQ 390
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ F C CPP ++G C+ C C + C C C G+ G+ C+
Sbjct: 391 DL--VNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCD 448
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
I+ ++C CQN A C+D ++GY C C PGY G HC+ ++DECAS+PC N C NEI
Sbjct: 449 ININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEIN 507
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
R+ C+CP +SG C+L+ID C PC NGA C + YFC C + G +C D C
Sbjct: 508 RFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHC 567
Query: 267 ASQPC----------------------------LHGGLCVDGENRYSCNCTGSGFTGTHC 298
+ PC HG +++C+C GFTGT+C
Sbjct: 568 RTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYC 626
Query: 299 ETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL- 357
+ C S PC N TC D V++Y C C G+ GA CE ++N+C+ NPC + G C +L
Sbjct: 627 HENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLV 686
Query: 358 -----------------SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVN- 399
S + Q T Y E + C+C G+ G C N
Sbjct: 687 NDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNS 746
Query: 400 ECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPH 459
C NPC NGGTC ++TC C + + G C+ C+ C N+GTC+
Sbjct: 747 SCLPNPCHNGGTCVVNGESFTCVC------KEGWEGPICAQNTNDCSPHPCYNSGTCV-- 798
Query: 460 FQDGQHGFSCLCPSGYTGSLCEI 482
DG + + C C G+ G C I
Sbjct: 799 --DGDNWYRCECAPGFAGPDCRI 819
Score = 309 bits (791), Expect = 1e-83
Identities = 165/527 (31%), Positives = 235/527 (44%), Gaps = 70/527 (13%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C+ N C N+C + TC+D C C K C + C + PC + +C
Sbjct: 371 CSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTG--KTCQLDANECEAKPCVNAKSCK 428
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
N S+ C C PG+ G C+ I C CQ+ C CICP GYAG CE
Sbjct: 429 NLIA--SYYCDCLPGWMGQNCDININDC-LGQCQNDASCRDLVNGYRCICPPGYAGDHCE 485
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
D DECAS+PC NG CQ+ I+ + C C G+ G C L++D C +PC+N A C N
Sbjct: 486 RDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRAS 545
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDAL----------------------- 243
Y C CP +Y G NC D C + PC +C A+
Sbjct: 546 DYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKC 605
Query: 244 -----GAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHC 298
G + CDC GF G +C N ++C S PC +GG C+DG N Y C C+ G+ G +C
Sbjct: 606 KSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICS-DGWEGAYC 664
Query: 299 ETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELS 358
ET + C PCHN TC D V+++ C C G+ G C ++C+ C + G C +
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEG 724
Query: 359 SEKQY---GRITGLPSSFSYHEA----------------SGYVCICQPGFTGIHCEEDVN 399
+ G G + + + + + C+C+ G+ G C ++ N
Sbjct: 725 DAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTN 784
Query: 400 ECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPH 459
+CS +PC N GTC + Y C C + G DC + C C TC+
Sbjct: 785 DCSPHPCYNSGTCVDGDNWYRCECA------PGFAGPDCRININECQSSPCAFGATCV-- 836
Query: 460 FQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTKGS 506
D +G+ C+CP G++G+ C+ E G + GSV G+
Sbjct: 837 --DEINGYRCVCPPGHSGAKCQ-------EVSGRPCITMGSVIPDGA 874
Score = 292 bits (748), Expect = 1e-78
Identities = 162/542 (29%), Positives = 247/542 (45%), Gaps = 88/542 (16%)
Query: 30 NNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTP 89
N C + +CK DC C L CD C +P CV+
Sbjct: 230 NRAICRQGCSPKHGSCK---LPGDCRCQYGWQGLY--CDK----CIPHP-----GCVHGI 275
Query: 90 GERSFLCKCPPGYSGTICETTIGSCGKNS-CQHGGIC-HQDPIYPVCICPAGYAGRFCEI 147
+ C C + G +C+ + CG + C +GG C + P C CP GY+G CEI
Sbjct: 276 CNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI 335
Query: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR 207
C S PC N C++ G+ C C PG+ G C +D+C+ + C + TC + +
Sbjct: 336 AEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNG 395
Query: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECA 267
+ C+CP ++G C+L+ +EC ++PC+N +C++ + +Y+CDC PG++G +C++N ++C
Sbjct: 396 FKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL 455
Query: 268 SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHC 327
Q C + C D N Y C C G+ G HCE + C S PC N C++ ++ + C C
Sbjct: 456 GQ-CQNDASCRDLVNGYRCICP-PGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 328 WPGYTGAQCEIDLNECNSNPCQSNGECVELSSE-----------------KQYGRIT--- 367
G++G C++D++ C NPCQ+ +C +S+ K + R T
Sbjct: 514 PTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCE 573
Query: 368 ------------GLPSSFSY--------------HEASGYVCICQPGFTGIHCEEDVNEC 401
P Y + C C GFTG +C E++N+C
Sbjct: 574 VIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDC 633
Query: 402 SSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQ 461
SNPC+NGGTC + +Y C C + G C + C+ C N GTC +
Sbjct: 634 ESNPCRNGGTCIDGVNSYKCIC------SDGWEGAYCETNINDCSQNPCHNGGTC----R 683
Query: 462 DGQHGFSCLCPSGYTG-------SLCEIAT-----TLSFEGDGFLWVKSGSVTTKGSVCN 509
D + F C C +G+ G S C+ AT T EGD F + G +G+ CN
Sbjct: 684 DLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGG--WEGTTCN 741
Query: 510 IA 511
IA
Sbjct: 742 IA 743
Score = 241 bits (615), Expect = 4e-63
Identities = 136/465 (29%), Positives = 199/465 (42%), Gaps = 88/465 (18%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
+ C + C N CQN + C + + D C C + K+C ++KD C + PC+ +
Sbjct: 520 NLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEG--KNCSHLKDHCRTTPCEVIDS 577
Query: 85 CV------NTP-GER-------------------SFLCKCPPGYSGTICETTIGSCGKNS 118
C +TP G R F C C G++GT C I C N
Sbjct: 578 CTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNP 637
Query: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGY 178
C++GG C CIC G+ G +CE + ++C+ +PC NG C+D ++ + C C G+
Sbjct: 638 CRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGW 697
Query: 179 QGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCEL-EIDECWSQPCLNGA 237
+G+ C +C C N TC +E + C+CP + G C + C PC NG
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGG 757
Query: 238 TCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTH 297
TC ++ C C G+ G C NT++C+ PC + G CVDG+N Y C C GF G
Sbjct: 758 TCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCEC-APGFAGPD 816
Query: 298 CETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL 357
C + C S PC ATC D ++ Y C C PG++GA+C+ E + PC + G +
Sbjct: 817 CRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ----EVSGRPCITMGSVIP- 871
Query: 358 SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPG 417
G ++D N TC+ L G
Sbjct: 872 --------------------------------DGAKWDDDCN-----------TCQCLNG 888
Query: 418 NYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQD 462
C S+ + G R C LL H +C + +CIP D
Sbjct: 889 RIAC-------SKVWCGPRPC---LLHKGHSECPSGQSCIPILDD 923
Score = 196 bits (498), Expect = 1e-49
Identities = 109/337 (32%), Positives = 161/337 (47%), Gaps = 45/337 (13%)
Query: 151 ECASSPCQNGAVCQDG---IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR 207
EC + C+ G + G + G C C G+QG +CD +C P C NE
Sbjct: 228 ECNRAICRQGCSPKHGSCKLPG-DCRCQYGWQGLYCD----KCIPHPGCVHGIC-NE--P 279
Query: 208 YTCICPHNYSGVNCELEIDECWS-QPCLNGATCQDA-LGAYFCDCAPGFLGDHCELNTDE 265
+ C+C N+ G C+ +++ C + QPCLNG TC + Y C C G+ G +CE+
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHA 339
Query: 266 CASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTC 325
C S PC + G C + + C C+ G+TG C T + C C + TC+D V+ + C
Sbjct: 340 CLSDPCHNRGSCKETSLGFECECS-PGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKC 398
Query: 326 HCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCIC 385
C P +TG C++D NEC + PC + C L + Y C C
Sbjct: 399 VCPPQWTGKTCQLDANECEAKPCVNAKSCKNL--------------------IASYYCDC 438
Query: 386 QPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGC 445
PG+ G +C+ ++N+C CQN +C +L Y C CP Y G C + C
Sbjct: 439 LPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP------PGYAGDHCERDIDEC 491
Query: 446 THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
CLN G C Q+ + F CLCP+G++G+LC++
Sbjct: 492 ASNPCLNGGHC----QNEINRFQCLCPTGFSGNLCQL 524
Score = 188 bits (477), Expect = 4e-47
Identities = 95/331 (28%), Positives = 146/331 (44%), Gaps = 19/331 (5%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
++C++N C SN C+N TC D C CSD C+ + C NPC T
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG--AYCETNINDCSQNPCHNGGT 681
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
C + + F C C G+ G C + C + +C +GG C+ + C+CP G+ G
Sbjct: 682 CRDLVND--FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTT 739
Query: 145 CEI-DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
C I + C +PC NG C + ++C C G++G C ++C+ PC N TC++
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVD 799
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 263
Y C C ++G +C + I+EC S PC GATC D + Y C C PG G C+
Sbjct: 800 GDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ--- 856
Query: 264 DECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNY 323
E + +PC+ G + ++ +C C +PC + +
Sbjct: 857 -EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQ 915
Query: 324 TCHCWPGYTGAQCEIDLNECNSNPCQSNGEC 354
+C I ++C +PC GEC
Sbjct: 916 SC----------IPILDDQCFVHPCTGVGEC 936
Score = 186 bits (473), Expect = 1e-46
Identities = 94/258 (36%), Positives = 137/258 (53%), Gaps = 37/258 (14%)
Query: 1113 VHGFINKPQEEQFLKISTNSVVTGC-LQLNVCNSN-PCLHGGNCEDIY-SSYHCSCPLGW 1169
VHG N+P + TN C LN C ++ PCL+GG C + Y CSCP G+
Sbjct: 272 VHGICNEPWQ---CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY 328
Query: 1170 SGKHCELNIDECFSNPCIH-GNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT 1228
SG +CE+ C S+PC + G+C + + C C PG+TG C +ID+C + C++G T
Sbjct: 329 SGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGT 388
Query: 1229 CISHTNGYSCLCFGNFTGKFCR--QSRLPSTVCGNEKT--NLT----------------- 1267
C NG+ C+C +TGK C+ + + C N K+ NL
Sbjct: 389 CQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCD 448
Query: 1268 ---------CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
C N +C + +C+C PG+ G+ CE+DIDECAS+PC+NGG CQ+ +N+
Sbjct: 449 ININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINR 508
Query: 1319 FQCLCDVAFAGERCEVDL 1336
FQCLC F+G C++D+
Sbjct: 509 FQCLCPTGFSGNLCQLDI 526
Score = 161 bits (407), Expect = 5e-39
Identities = 71/198 (35%), Positives = 102/198 (51%), Gaps = 7/198 (3%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
+N C SNPC +GG C D +SY C C GW G +CE NI++C NPC +G C D V +
Sbjct: 630 INDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDF 689
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
+C C+ G+ G C C C NG TC + + C+C G + G C +R S +
Sbjct: 690 YCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
C+NGG C C+C+ G+ G C ++ ++C+ PC N G C D N
Sbjct: 750 PN------PCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNW 803
Query: 1319 FQCLCDVAFAGERCEVDL 1336
++C C FAG C +++
Sbjct: 804 YRCECAPGFAGPDCRINI 821
Score = 160 bits (406), Expect = 6e-39
Identities = 91/310 (29%), Positives = 128/310 (41%), Gaps = 39/310 (12%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ ++C N C N C N TC+D D C C + K C + C C
Sbjct: 660 EGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKG--KTCHSRDSQCDEATCNNG 717
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICE-TTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA 141
TC + +F C CP G+ GT C SC N C +GG C + C+C G+
Sbjct: 718 GTCYDEGD--AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE 775
Query: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
G C + ++C+ PC N C DG + Y C C PG+ G C + ++EC S PC ATC
Sbjct: 776 GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATC 835
Query: 202 LNEIGRYTCICPHNYSGVNCELEI-------------------DECWSQPCLNGATCQDA 242
++EI Y C+CP +SG C+ E+ D+C + CLNG + A
Sbjct: 836 VDEINGYRCVCPPGHSGAKCQ-EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNG---RIA 891
Query: 243 LGAYFCDCAPGFL---------GDHC-ELNTDECASQPCLHGGLCVDGE-NRYSCNCTGS 291
+C P L G C + D+C PC G C CT
Sbjct: 892 CSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSD 951
Query: 292 GFTGTHCETL 301
+ +C +
Sbjct: 952 SYYQDNCANI 961
Score = 158 bits (400), Expect = 3e-38
Identities = 77/255 (30%), Positives = 119/255 (46%), Gaps = 61/255 (23%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
+ +N C C + +C D+ + Y C CP G++G HCE +IDEC SNPC++G +C + +
Sbjct: 449 ININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEIN 507
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR--- 1253
+ C C G++G C++DID C+ + C NGA C + + Y C C ++ GK C +
Sbjct: 508 RFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHC 567
Query: 1254 --------------------------LPSTVCG--------------------------- 1260
+ S VCG
Sbjct: 568 RTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCH 627
Query: 1261 ---NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
N+ + C NGG C + KC+C G+ G +CE +I++C+ +PC NGG C+DL+N
Sbjct: 628 ENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVN 687
Query: 1318 KFQCLCDVAFAGERC 1332
F C C + G+ C
Sbjct: 688 DFYCDCKNGWKGKTC 702
Score = 157 bits (396), Expect = 9e-38
Identities = 76/260 (29%), Positives = 116/260 (44%), Gaps = 59/260 (22%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
L N C + PC++ +C+++ +SY+C C GW G++C++NI++C +C D V
Sbjct: 411 LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR------- 1250
Y C C PGY G +CE DID C S+ C NG C + N + CLC F+G C+
Sbjct: 471 YRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCE 530
Query: 1251 -QSRLPSTVCGNEKTNLTC-----YNGGNCTEFQTELK---------------------- 1282
C N ++ C Y G NC+ + +
Sbjct: 531 PNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEG 590
Query: 1283 ------------------------CMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
C C GFTG +C ++I++C S+PC NGG C D +N
Sbjct: 591 VRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNS 650
Query: 1319 FQCLCDVAFAGERCEVDLAD 1338
++C+C + G CE ++ D
Sbjct: 651 YKCICSDGWEGAYCETNIND 670
Score = 132 bits (333), Expect = 2e-30
Identities = 70/201 (34%), Positives = 106/201 (52%), Gaps = 25/201 (12%)
Query: 1143 CNSNPCLHGGNCEDIYSSYH----CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAA 1197
CN C G C + S C C GW G +C D+C +P C+HG C++
Sbjct: 229 CNRAICRQG--CSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGCVHGICNE---P 279
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQ-CANGATCISHT--NGYSCLCFGNFTGKFCRQSRL 1254
+ C CE + G C+ D++ C +HQ C NG TC S+T + Y C C ++G C +
Sbjct: 280 WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTC-SNTGPDKYQCSCPEGYSGPNC---EI 335
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
C ++ C+N G+C E +C C PG+TG C +ID+C+ + C +GG CQD
Sbjct: 336 AEHACLSD----PCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQD 391
Query: 1315 LLNKFQCLCDVAFAGERCEVD 1335
L+N F+C+C + G+ C++D
Sbjct: 392 LVNGFKCVCPPQWTGKTCQLD 412
Score = 129 bits (323), Expect = 3e-29
Identities = 67/198 (33%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 1144 NSNPCLHGGNCEDIYSS-YHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
+SN C G C+ + C C G++G +C NI++C SNPC +G C D V +Y C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCI 654
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
C G+ G CE +I++C + C NG TC N + C C + GK C +
Sbjct: 655 CSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSR-------DS 707
Query: 1262 EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-KDIDECASDPCVNGGLCQDLLNKFQ 1320
+ TC NGG C + KCMC G+ G C C +PC NGG C F
Sbjct: 708 QCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFT 767
Query: 1321 CLCDVAFAGERCEVDLAD 1338
C+C + G C + D
Sbjct: 768 CVCKEGWEGPICAQNTND 785
Score = 127 bits (318), Expect = 1e-28
Identities = 65/207 (31%), Positives = 105/207 (50%), Gaps = 15/207 (7%)
Query: 1138 LQLNVCNSNP-CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN-PCIHGNCSDRV 1195
L + C +P C+HG C + + C C W G+ C+ +++ C ++ PC++G
Sbjct: 260 LYCDKCIPHPGCVHG-ICNE---PWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNT 315
Query: 1196 AA--YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR 1253
Y C+C GY+G NCE+ C S C N +C + G+ C C +TG C
Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTC---- 371
Query: 1254 LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQ 1313
ST + N C +GG C + KC+C P +TG+ C+ D +EC + PCVN C+
Sbjct: 372 --STNIDDCSPN-NCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCK 428
Query: 1314 DLLNKFQCLCDVAFAGERCEVDLADDL 1340
+L+ + C C + G+ C++++ D L
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCL 455
Score = 108 bits (270), Expect = 4e-23
Identities = 62/190 (32%), Positives = 89/190 (46%), Gaps = 19/190 (10%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCT 1201
C NPC +GG C S+ C C GW G C N ++C +PC + G C D Y C
Sbjct: 748 CLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCE 807
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ-SRLPSTVCG 1260
C PG+ G +C ++I+ CQS CA GATC+ NGY C+C +G C++ S P G
Sbjct: 808 CAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMG 867
Query: 1261 ----------NEKTNLTCYNGG-NCTEFQTELK-CMCRPGF----TGEWCEKDI-DECAS 1303
++ C NG C++ + C+ G +G+ C + D+C
Sbjct: 868 SVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFV 927
Query: 1304 DPCVNGGLCQ 1313
PC G C+
Sbjct: 928 HPCTGVGECR 937
Score = 65.1 bits (157), Expect = 5e-10
Identities = 51/175 (29%), Positives = 70/175 (40%), Gaps = 50/175 (28%)
Query: 317 EDSVDNYTCH------CWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLP 370
+D +Y C C G+ G +C + C +G C LP
Sbjct: 204 DDFFGHYACDQNGNKTCMEGWMGPECNRAI--CRQGCSPKHGSCK-------------LP 248
Query: 371 SSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNP-CQNGGTCENLPGNYTCHCPFDNLS 429
C CQ G+ G++C++ C +P C +G C+ P+ L
Sbjct: 249 GD----------CRCQYGWQGLYCDK----CIPHPGCVHG----------ICNEPWQCLC 284
Query: 430 RTFYGGRDCSDILLGC-THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
T +GG+ C L C THQ CLN GTC G + C CP GY+G CEIA
Sbjct: 285 ETNWGGQLCDKDLNYCGTHQPCLNGGTCS---NTGPDKYQCSCPEGYSGPNCEIA 336
Score = 58.9 bits (141), Expect = 3e-08
Identities = 29/82 (35%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
Query: 884 GCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHG 936
G AGD+ C SNPC NGG C + + F C CP SG C+ ++ +C +PC +G
Sbjct: 478 GYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNG 537
Query: 937 AQCQPVLQGFECIANAVFNGQS 958
AQC + C + G++
Sbjct: 538 AQCYNRASDYFCKCPEDYEGKN 559
Score = 57.8 bits (138), Expect = 7e-08
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGF 946
+++C S+PCHN G C F C C +G C + C + C HG CQ ++ GF
Sbjct: 337 EHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGF 396
Query: 947 ECIANAVFNGQSGQI 961
+C+ + G++ Q+
Sbjct: 397 KCVCPPQWTGKTCQL 411
Score = 54.7 bits (130), Expect = 6e-07
Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
N C NPCHNGG C +DF C C GK C C + C +G C F+
Sbjct: 669 NDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFK 728
Query: 948 CIANAVFNGQSGQILFRSN 966
C+ + G + I S+
Sbjct: 729 CMCPGGWEGTTCNIARNSS 747
Score = 53.5 bits (127), Expect = 1e-06
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C+SNPC NGG C + + C C G CE + C +PC +G C+ ++ F
Sbjct: 631 NDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFY 690
Query: 948 CIANAVFNGQS 958
C + G++
Sbjct: 691 CDCKNGWKGKT 701
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 12/113 (10%)
Query: 860 QNLEFFPNPTNNA--------SLNPVLVNVTQG--CAGD-NSCKSNPCHNGGVCHSRWDD 908
+N PNP +N S V +G CA + N C +PC+N G C +
Sbjct: 744 RNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNW 803
Query: 909 FSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQ 960
+ C C +G C + C SPC GA C + G+ C+ +G Q
Sbjct: 804 YRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
Score = 48.9 bits (115), Expect = 3e-05
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ--WCGFSPCPHGAQCQPVLQG 945
D+ C C+NGG C+ D F C CP G C + C +PC +G C +
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGES 765
Query: 946 FECIANAVFNG 956
F C+ + G
Sbjct: 766 FTCVCKEGWEG 776
Score = 48.1 bits (113), Expect = 6e-05
Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C N C +GG C + F C CP +GK C+ + C PC + C+ ++ +
Sbjct: 376 DDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYY 435
Query: 948 CIANAVFNGQSGQI 961
C + GQ+ I
Sbjct: 436 CDCLPGWMGQNCDI 449
Score = 48.1 bits (113), Expect = 6e-05
Identities = 52/182 (28%), Positives = 65/182 (35%), Gaps = 50/182 (27%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVA 1196
+ +N C S+PC G C D + Y C CP G SG C+ E PCI G+ A
Sbjct: 819 ININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ----EVSGRPCITMGSVIPDGA 874
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANG-----------ATCISH------TNGYSCL 1239
+ D+C + QC NG C+ H +G SC+
Sbjct: 875 KWD----------------DDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCI 918
Query: 1240 ------CFGN-FTG-KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQ-TELKCMCRPGFT 1290
CF + TG CR S L K Y NC T K M PG T
Sbjct: 919 PILDDQCFVHPCTGVGECRSSSLQPV---KTKCTSDSYYQDNCANITFTFNKEMMSPGLT 975
Query: 1291 GE 1292
E
Sbjct: 976 TE 977
Score = 47.0 bits (110), Expect = 1e-04
Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 889 NSCKSN-PCHNGGVCHSRWDD-FSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQG 945
N C ++ PC NGG C + D + CSCP SG CE + C PC + C+ G
Sbjct: 298 NYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLG 357
Query: 946 FECIANAVFNG 956
FEC + + G
Sbjct: 358 FECECSPGWTG 368
Score = 47.0 bits (110), Expect = 1e-04
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C C N C + + C CP +G CE ++ C +PC +G CQ + F+
Sbjct: 452 NDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQ 510
Query: 948 CIANAVFNGQSGQI 961
C+ F+G Q+
Sbjct: 511 CLCPTGFSGNLCQL 524
Score = 47.0 bits (110), Expect = 1e-04
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPVL------ 943
C+ NPC NG C++R D+ C CP GK C ++ C +PC C +
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP 588
Query: 944 QGFECIANAVFNGQSGQILFRSNGNIT 970
+G I++ V G G+ +S G T
Sbjct: 589 EGVRYISSNVC-GPHGKCKSQSGGKFT 614
Score = 42.7 bits (99), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D+CE PCQ+ +C N Y C C YEG NC
Sbjct: 527 DYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNC 560
Score = 38.5 bits (88), Expect = 0.046
Identities = 25/100 (25%), Positives = 31/100 (31%), Gaps = 45/100 (45%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ---------------------- 926
N C+S+PC G C + + C CP SG C+EV
Sbjct: 822 NECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCN 881
Query: 927 --------------WC---------GFSPCPHGAQCQPVL 943
WC G S CP G C P+L
Sbjct: 882 TCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPIL 921
Score = 37.7 bits (86), Expect = 0.078
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC +RG C L ++C+C + GP C
Sbjct: 340 CLSDPCHNRGSCKETSLGFECECSPGWTGPTC 371
Score = 37.7 bits (86), Expect = 0.078
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
CE++PC + C NL SY CDC + G NC
Sbjct: 416 CEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447
Score = 37.0 bits (84), Expect = 0.13
Identities = 15/32 (46%), Positives = 20/32 (62%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
CES PC++ G CI+ SY+C C +EG C
Sbjct: 633 CESNPCRNGGTCIDGVNSYKCICSDGWEGAYC 664
Score = 36.6 bits (83), Expect = 0.17
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 9/92 (9%)
Query: 893 SNPCHNGGVCHSR-WDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIA 950
SN C G C S+ F+C C +G C E + C +PC +G C + ++CI
Sbjct: 596 SNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655
Query: 951 NAVFNGQSGQILFRS-------NGNITRELTN 975
+ + G + NG R+L N
Sbjct: 656 SDGWEGAYCETNINDCSQNPCHNGGTCRDLVN 687
Score = 35.0 bits (79), Expect = 0.51
Identities = 15/30 (50%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 679 QPCQSRGRCINLWLS-YQCDCHRPYEGPNC 707
QPC + G C N YQC C Y GPNC
Sbjct: 304 QPCLNGGTCSNTGPDKYQCSCPEGYSGPNC 333
Score = 33.1 bits (74), Expect = 1.9
Identities = 11/32 (34%), Positives = 16/32 (50%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC + G C +L + CDC ++G C
Sbjct: 671 CSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTC 702
Score = 33.1 bits (74), Expect = 1.9
Identities = 11/32 (34%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC + G C++ Y+C+C + GP+C
Sbjct: 786 CSPHPCYNSGTCVDGDNWYRCECAPGFAGPDC 817
Score = 32.7 bits (73), Expect = 2.5
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 661 GSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
G++ N+ R C PC + G C+ S+ C C +EGP C
Sbjct: 737 GTTCNI----ARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPIC 779
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 316 bits (810), Expect = 9e-86
Identities = 171/554 (30%), Positives = 242/554 (43%), Gaps = 97/554 (17%)
Query: 24 NSFCNKNNTRCLSNSCQN--NSTCKDFSKDNDCS---CSDTANNLDKDCDNMKDPC---- 74
N FC N +C N C D +C C N L C + C
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSY 266
Query: 75 -----FSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNS-CQHGGIC-HQ 127
F + C CV+ + C C + G +C+ + CG + C +GG C +
Sbjct: 267 GWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 128 DPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
+P C CP GY+GR CE C S+PC NG C + G+ C C G+ G C L++
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 188 DECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
DECAS+PC TC++++ + CICP + G C+L+ +EC +PCLN +C++ +G Y+
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYY 446
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
CDC PG+ G +C +N ++C Q C HGG C D N Y C C GF G HCE C S
Sbjct: 447 CDCIPGWKGINCHINVNDCRGQ-CQHGGTCKDLVNGYQCVCP-RGFGGRHCELERDECAS 504
Query: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSE------K 361
PCH+ CED D + CHC G++G CE+D++ C +PC++ C L +
Sbjct: 505 SPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD 564
Query: 362 QYG----------------RI---------TGLPSSFS-----------YHEASGYVCIC 385
+G R+ G+P + + + CIC
Sbjct: 565 DFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC 624
Query: 386 QPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFD------------------- 426
GFTG +C E++++C PC+NGGTC + + C CP
Sbjct: 625 DSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCH 684
Query: 427 ------NLSRTFY-------GGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPS 473
+L FY G+ C C C N GTC D F C CP
Sbjct: 685 SRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC----YDSGDTFRCACPP 740
Query: 474 GYTGSLCEIATTLS 487
G+ GS C +A S
Sbjct: 741 GWKGSTCAVAKNSS 754
Score = 297 bits (760), Expect = 5e-80
Identities = 171/538 (31%), Positives = 226/538 (42%), Gaps = 97/538 (18%)
Query: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDN-DCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
C+K+ C S+ C N TC + D C+C D + ++C+ + C SNPC +
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG--RNCEKAEHACTSNPCANGGS 361
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
C P F C CP G+SG C I C N C GG C CICP + G
Sbjct: 362 CHEVPS--GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGAT 419
Query: 145 CEIDHDECASSPC-------------------------------------QNGAVCQDGI 167
C++D +EC PC Q+G C+D +
Sbjct: 420 CQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLV 479
Query: 168 DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDE 227
+GY C C G+ GRHC+LE DECAS PC + C + + C CP +SG CE+++D
Sbjct: 480 NGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDL 539
Query: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC--------------------- 266
C PC NGA C + G Y+C C F G +C + + C
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPG 599
Query: 267 --ASQPCLHGGLCVDGEN-RYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNY 323
AS C G CV +SC C SGFTGT+C + C +PC N TC D VD +
Sbjct: 600 TAASGVCGPHGRCVSQPGGNFSCICD-SGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 658
Query: 324 TCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL------------------SSEKQYGR 365
C C G+ G C+ + N+C +PC S G C +L S E Q
Sbjct: 659 RCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA 718
Query: 366 ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTCENLPGNYTCHCP 424
T Y + C C PG+ G C N C NPC NGGTC +++C C
Sbjct: 719 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCIC- 777
Query: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
R + GR C+ C C N G C+ DG + F C C G+ G C I
Sbjct: 778 -----RDGWEGRTCTHNTNDCNPLPCYNGGICV----DGVNWFRCECAPGFAGPDCRI 826
Score = 240 bits (612), Expect = 8e-63
Identities = 134/473 (28%), Positives = 191/473 (40%), Gaps = 65/473 (13%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C C S+ C + C+D + C C + C+ D C +PC+ A C
Sbjct: 495 CELERDECASSPCHSGGLCEDLADGFHCHCPQGFSG--PLCEVDVDLCEPSPCRNGARCY 552
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQ------------------------HG 122
N G+ + C CP + G C C +C+ HG
Sbjct: 553 NLEGD--YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610
Query: 123 GICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRH 182
Q CIC +G+ G +C + D+C PC+NG C D +D + CFC G++G
Sbjct: 611 RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670
Query: 183 CDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDA 242
CD ++C DPC + C + + + C C + G C +C + C NG TC D+
Sbjct: 671 CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS 730
Query: 243 LGAYFCDCAPGFLGDHCEL-NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETL 301
+ C C PG+ G C + C PC++GG CV +SC C G+ G C
Sbjct: 731 GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICR-DGWEGRTCTHN 789
Query: 302 MPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEK 361
C PC+N C D V+ + C C PG+ G C I+++EC S+PC CV+
Sbjct: 790 TNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVD----- 844
Query: 362 QYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTC 421
E +GY C C PG G C+E + C + GT ++
Sbjct: 845 ---------------EINGYRCSCPPGRAGPRCQEVIG--FGRSCWSRGTPFPHGSSWVE 887
Query: 422 HCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSG 474
C N R G RDCS + C + CL G S CP G
Sbjct: 888 DC---NSCRCLDGRRDCSKV--WCGWKPCLLAGQ--------PEALSAQCPLG 927
Score = 178 bits (451), Expect = 4e-44
Identities = 79/197 (40%), Positives = 108/197 (54%), Gaps = 9/197 (4%)
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYH 1199
+ C SNPC +GG+C ++ S + C CP GWSG C L+IDEC SNPC G C D+V +
Sbjct: 349 HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
C C + G C++D + C+ C N +C + GY C C + G C + C
Sbjct: 409 CICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINC---HINVNDC 465
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
+ C +GG C + +C+C GF G CE + DECAS PC +GGLC+DL + F
Sbjct: 466 RGQ-----CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGF 520
Query: 1320 QCLCDVAFAGERCEVDL 1336
C C F+G CEVD+
Sbjct: 521 HCHCPQGFSGPLCEVDV 537
Score = 169 bits (428), Expect = 2e-41
Identities = 73/201 (36%), Positives = 106/201 (52%), Gaps = 9/201 (4%)
Query: 1135 TGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSD 1193
T L ++ C SNPC GG C D + C CP W G C+L+ +EC PC++ +C +
Sbjct: 381 TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKN 440
Query: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR 1253
+ Y+C C PG+ G+NC +++++C+ QC +G TC NGY C+C F G+ C R
Sbjct: 441 LIGGYYCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDLVNGYQCVCPRGFGGRHCELER 499
Query: 1254 LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQ 1313
+E + C++GG C + C C GF+G CE D+D C PC NG C
Sbjct: 500 -------DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCY 552
Query: 1314 DLLNKFQCLCDVAFAGERCEV 1334
+L + C C F G+ C V
Sbjct: 553 NLEGDYYCACPDDFGGKNCSV 573
Score = 168 bits (426), Expect = 3e-41
Identities = 82/221 (37%), Positives = 113/221 (51%), Gaps = 19/221 (8%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
+ +N C C HGG C+D+ + Y C CP G+ G+HCEL DEC S+PC G C D
Sbjct: 460 INVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD 518
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
+HC C G++G CEVD+D C+ C NGA C + Y C C +F GK C R P
Sbjct: 519 GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC 578
Query: 1257 TV--------CGNEK--------TNLTCYNGGNC-TEFQTELKCMCRPGFTGEWCEKDID 1299
CG++ + C G C ++ C+C GFTG +C ++ID
Sbjct: 579 PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID 638
Query: 1300 ECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
+C PC NGG C D ++ F+C C + GE C+ + D L
Sbjct: 639 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCL 679
Score = 159 bits (402), Expect = 2e-38
Identities = 84/259 (32%), Positives = 122/259 (47%), Gaps = 16/259 (6%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ C+ N CL + C + C D D C+C D K C + + C + C
Sbjct: 667 EGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKG--KTCHSREFQCDAYTCSNG 724
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETT-IGSCGKNSCQHGGICHQDPIYPVCICPAGYA 141
TC ++ +F C CPPG+ G+ C SC N C +GG C CIC G+
Sbjct: 725 GTCYDSGD--TFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE 782
Query: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
GR C + ++C PC NG +C DG++ + C C PG+ G C + +DEC S PC ATC
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATC 842
Query: 202 LNEIGRYTCICPHNYSGVNCELEID---ECWSQ--PCLNGATCQDALGAYFCDCAPGFLG 256
++EI Y C CP +G C+ I CWS+ P +G++ + + C C G
Sbjct: 843 VDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLDG--- 897
Query: 257 DHCELNTDECASQPCLHGG 275
+ + C +PCL G
Sbjct: 898 -RRDCSKVWCGWKPCLLAG 915
Score = 150 bits (380), Expect = 6e-36
Identities = 65/195 (33%), Positives = 97/195 (49%), Gaps = 7/195 (3%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYHCT 1201
C PC +GG C D ++ C CP GW G+ C+ N ++C +PC G C D V ++C
Sbjct: 640 CLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCA 699
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
C+ G+ G C C ++ C+NG TC + + C C + G C ++ S +
Sbjct: 700 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN- 758
Query: 1262 EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQC 1321
C NGG C C+CR G+ G C + ++C PC NGG+C D +N F+C
Sbjct: 759 -----PCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRC 813
Query: 1322 LCDVAFAGERCEVDL 1336
C FAG C +++
Sbjct: 814 ECAPGFAGPDCRINI 828
Score = 150 bits (379), Expect = 8e-36
Identities = 69/195 (35%), Positives = 97/195 (49%), Gaps = 9/195 (4%)
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYH 1199
N C +PC G C D+ + ++C+C GW GK C +C + C +G C D +
Sbjct: 676 NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735
Query: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C PG+ G C V ++ C + C NG TC+ +SC+C + G+ C +
Sbjct: 736 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNT----- 790
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
N+ L CYNGG C + +C C PGF G C +IDEC S PC G C D +N
Sbjct: 791 --NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEING 848
Query: 1319 FQCLCDVAFAGERCE 1333
++C C AG RC+
Sbjct: 849 YRCSCPPGRAGPRCQ 863
Score = 140 bits (352), Expect = 1e-32
Identities = 66/176 (37%), Positives = 97/176 (55%), Gaps = 17/176 (9%)
Query: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
C C GW G+ C DEC P C+HG+C V + C CE + G+ C+ D++ C SH
Sbjct: 262 CRCSYGWQGRFC----DECVPYPGCVHGSC---VEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 1222 Q-CANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
C NG TCI+ + Y C C ++G+ C ++ + T+ C NGG+C E +
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAE-------HACTSNPCANGGSCHEVPS 367
Query: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
+C C G++G C DIDECAS+PC GG C D ++ F+C+C + G C++D
Sbjct: 368 GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLD 423
Score = 117 bits (292), Expect = 1e-25
Identities = 66/238 (27%), Positives = 106/238 (44%), Gaps = 21/238 (8%)
Query: 1115 GFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCED-------IYSS----YHC 1163
G++ K +E K N + GC C + G C++ ++ S + C
Sbjct: 234 GWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQC 293
Query: 1164 SCPLGWSGKHCELNIDECFSN-PCIHGNCSDRVAA--YHCTCEPGYTGVNCEVDIDNCQS 1220
+C W G C+ +++ C S+ PC +G Y CTC GY+G NCE C S
Sbjct: 294 NCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS 353
Query: 1221 HQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTE 1280
+ CANG +C +G+ C C ++G C L C + C GG C +
Sbjct: 354 NPCANGGSCHEVPSGFECHCPSGWSGPTCA---LDIDECASNP----CAAGGTCVDQVDG 406
Query: 1281 LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
+C+C + G C+ D +EC PC+N C++L+ + C C + G C +++ D
Sbjct: 407 FECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVND 464
Score = 109 bits (272), Expect = 2e-23
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 1/110 (0%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
C NPC++GG C +S+ C C GW G+ C N ++C PC +G C D V + C
Sbjct: 755 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 814
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
C PG+ G +C ++ID CQS CA GATC+ NGY C C G C++
Sbjct: 815 CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQE 864
Score = 101 bits (252), Expect = 4e-21
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 9/158 (5%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL-NIDECFSNPCIHGN-CSDRVAAYHC 1200
C++ C +GG C D ++ C+CP GW G C + C NPC++G C A++ C
Sbjct: 716 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSC 775
Query: 1201 TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG 1260
C G+ G C + ++C C NG C+ N + C C F G CR +
Sbjct: 776 ICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCR-------INI 828
Query: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
+E + C G C + +C C PG G C++ I
Sbjct: 829 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866
Score = 90.5 bits (223), Expect = 1e-17
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 24/188 (12%)
Query: 1156 DIYSSYHC------SCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGV 1209
D + Y C +C GW GK C+ + + N +HG C+ C C G+ G
Sbjct: 216 DFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCN-LLHGGCT---VPGECRCSYGWQGR 271
Query: 1210 NCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCY 1269
C D C + +C+ + C C N+ G C + CG+ C
Sbjct: 272 FC----DECVPYPGCVHGSCVEP---WQCNCETNWGGLLCDKDL---NYCGSHHP---CT 318
Query: 1270 NGGNCTEFQTE-LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFA 1328
NGG C + + +C C G++G CEK C S+PC NGG C ++ + F+C C ++
Sbjct: 319 NGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWS 378
Query: 1329 GERCEVDL 1336
G C +D+
Sbjct: 379 GPTCALDI 386
Score = 65.1 bits (157), Expect = 5e-10
Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGF 946
+++C SNPC NGG CH F C CP+ SG C ++ C +PC G C + GF
Sbjct: 348 EHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGF 407
Query: 947 ECIANAVFNGQSGQI 961
ECI + G + Q+
Sbjct: 408 ECICPEQWVGATCQL 422
Score = 61.2 bits (147), Expect = 7e-09
Identities = 28/71 (39%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S+PCH+GG+C D F C CP SG CE +V C SPC +GA+C + +
Sbjct: 500 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 559
Query: 948 CIANAVFNGQS 958
C F G++
Sbjct: 560 CACPDDFGGKN 570
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 889 NSCKSN-PCHNGGVC-HSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQG 945
N C S+ PC NGG C ++ D + C+CP SG+ CE+ + C +PC +G C V G
Sbjct: 309 NYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSG 368
Query: 946 FECIANAVFNG 956
FEC + ++G
Sbjct: 369 FECHCPSGWSG 379
Score = 52.0 bits (123), Expect = 4e-06
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C PC+NGG+C + F C C +G C + C SPC +GA C + G+
Sbjct: 791 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 850
Query: 948 C 948
C
Sbjct: 851 C 851
Score = 50.4 bits (119), Expect = 1e-05
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C+ C +GG C + + C CP G+ CE E C SPC G C+ + GF
Sbjct: 463 NDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 521
Query: 948 CIANAVFNG 956
C F+G
Sbjct: 522 CHCPQGFSG 530
Score = 46.6 bits (109), Expect = 2e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C PC NGG C D F C CP+ G+ C+ C PC +C ++ F
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 948 CIANAVFNGQS 958
C + + G++
Sbjct: 698 CACDDGWKGKT 708
Score = 46.6 bits (109), Expect = 2e-04
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ--WCGFSPCPHGAQCQPVLQGFEC 948
C + C NGG C+ D F C+CP G C + C +PC +G C F C
Sbjct: 716 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSC 775
Query: 949 IANAVFNGQS 958
I + G++
Sbjct: 776 ICRDGWEGRT 785
Score = 46.6 bits (109), Expect = 2e-04
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 882 TQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQ 940
T A ++SC NPC NGG C FSC C G+ C C PC +G C
Sbjct: 746 TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV 805
Query: 941 PVLQGFECIANAVFNGQSGQI 961
+ F C F G +I
Sbjct: 806 DGVNWFRCECAPGFAGPDCRI 826
Score = 45.4 bits (106), Expect = 4e-04
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQGFE 947
N C +PCH+ G C+ +DF C+C GK C ++ C C +G C F
Sbjct: 676 NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735
Query: 948 CIANAVFNGQS 958
C + G +
Sbjct: 736 CACPPGWKGST 746
Score = 45.1 bits (105), Expect = 5e-04
Identities = 28/112 (25%), Positives = 39/112 (34%), Gaps = 39/112 (34%)
Query: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPC--------- 933
CA D + C SNPC GG C + D F C CP G C+ + C PC
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNL 441
Query: 934 ----------------------------PHGAQCQPVLQGFECIANAVFNGQ 957
HG C+ ++ G++C+ F G+
Sbjct: 442 IGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGR 493
Score = 44.7 bits (104), Expect = 6e-04
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNID---ECFS--NPCIHGN 1190
+ ++ C S+PC +G C D + Y CSCP G +G C+ I C+S P HG+
Sbjct: 826 INIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGS 883
Score = 43.1 bits (100), Expect = 0.002
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV------QWCGFSPCPHGA 937
+ C+S+PC G C + + CSCP +G C+EV W +P PHG+
Sbjct: 829 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGS 883
Score = 42.0 bits (97), Expect = 0.004
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGA 937
C+ +PC NG C++ D+ C+CP GK C + PCP GA
Sbjct: 540 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPR----EPCPGGA 582
Score = 38.1 bits (87), Expect = 0.060
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D CE PC++ RC NL Y C C + G NC
Sbjct: 538 DLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNC 571
Score = 38.1 bits (87), Expect = 0.060
Identities = 31/123 (25%), Positives = 46/123 (37%), Gaps = 15/123 (12%)
Query: 843 LNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGD------NSCKSNPC 896
L G ++ C D N ++ P P V GC D + S C
Sbjct: 554 LEGDYYCACPDDFGGKNCSVPREPCPGGAC-------RVIDGCGSDAGPGMPGTAASGVC 606
Query: 897 HNGGVCHSR-WDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
G C S+ +FSC C + +G C E + C PC +G C + F C + +
Sbjct: 607 GPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW 666
Query: 955 NGQ 957
G+
Sbjct: 667 EGE 669
Score = 36.6 bits (83), Expect = 0.17
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ +D C S PC S G C +L + C C + + GP C
Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLC 533
Score = 34.7 bits (78), Expect = 0.66
Identities = 14/32 (43%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
CE +PC + C NL Y CDC ++G NC
Sbjct: 427 CEGKPCLNAFSCKNLIGGYYCDCIPGWKGINC 458
Score = 34.7 bits (78), Expect = 0.66
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC SRGRC +L + C C ++G C
Sbjct: 678 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTC 709
Score = 32.7 bits (73), Expect = 2.5
Identities = 11/32 (34%), Positives = 16/32 (50%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC + G C + ++C C + GP C
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382
Score = 32.3 bits (72), Expect = 3.3
Identities = 14/42 (33%), Positives = 18/42 (42%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGR 715
D C+S PC C++ Y+C C GP C GR
Sbjct: 829 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 870
Score = 32.0 bits (71), Expect = 4.3
Identities = 13/34 (38%), Positives = 20/34 (58%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C QPC++ G CI+ +++C C +EG C
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 671
Score = 31.2 bits (69), Expect = 7.3
Identities = 11/34 (32%), Positives = 17/34 (50%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PC + G C++ ++C C + G C
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATC 420
Score = 30.8 bits (68), Expect = 9.6
Identities = 11/32 (34%), Positives = 15/32 (46%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC + G C+ S+ C C +EG C
Sbjct: 755 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTC 786
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 306 bits (785), Expect = 7e-83
Identities = 169/501 (33%), Positives = 225/501 (44%), Gaps = 61/501 (12%)
Query: 27 CNKNNTRCLSNS-CQNNSTCKDFSKDN-DCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
C+K+ C S+ C N TC + D C+C D + ++C+ + C SNPC +
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG--RNCEKAEHACTSNPCANGGS 361
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
C P F C CP G+SG C I C N C GG C CICP + G
Sbjct: 362 CHEVPS--GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGAT 419
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
C++D ++C CQ+G C+D ++GY C C G+ GRHC+LE DECAS PC + C +
Sbjct: 420 CQLDVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 478
Query: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
+ C CP +SG CE+++D C PC NGA C + G Y+C C F G +C + +
Sbjct: 479 ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 538
Query: 265 EC-----------------------ASQPCLHGGLCVDGE-NRYSCNCTGSGFTGTHCET 300
C AS C G CV +SC C SGFTGT+C
Sbjct: 539 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC-DSGFTGTYCHE 597
Query: 301 LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL--- 357
+ C +PC N TC D VD + C C G+ G C+ + N+C +PC S G C +L
Sbjct: 598 NIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVND 657
Query: 358 ---------------SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVN-EC 401
S E Q T Y + C C PG+ G C N C
Sbjct: 658 FYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSC 717
Query: 402 SSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQ 461
NPC NGGTC +++C C R + GR C+ C C N G C+
Sbjct: 718 LPNPCVNGGTCVGSGASFSCIC------RDGWEGRTCTHNTNDCNPLPCYNGGICV---- 767
Query: 462 DGQHGFSCLCPSGYTGSLCEI 482
DG + F C C G+ G C I
Sbjct: 768 DGVNWFRCECAPGFAGPDCRI 788
Score = 297 bits (761), Expect = 4e-80
Identities = 163/516 (31%), Positives = 224/516 (43%), Gaps = 59/516 (11%)
Query: 24 NSFCNKNNTRCLSNSCQN--NSTCKDFSKDNDCS---CSDTANNLDKDCDNMKDPC---- 74
N FC N +C N C D +C C N L C + C
Sbjct: 208 NKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGC-TVPGECRCSY 266
Query: 75 -----FSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGK-NSCQHGGIC-HQ 127
F + C CV+ + C C + G +C+ + CG + C +GG C +
Sbjct: 267 GWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINA 326
Query: 128 DPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
+P C CP GY+GR CE C S+PC NG C + G+ C C G+ G C L++
Sbjct: 327 EPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI 386
Query: 188 DECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
DECAS+PC TC++++ + CICP + G C+L++++C Q C +G TC+D + Y
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGTCKDLVNGYQ 445
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
C C GF G HCEL DECAS PC GGLC D + + C+C GF+G CE + LC
Sbjct: 446 CVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCP-QGFSGPLCEVDVDLCEP 504
Query: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGR-- 365
PC N A C + +Y C C + G C + C C+ C + G
Sbjct: 505 SPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA 564
Query: 366 --ITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
+ G + CIC GFTG +C E++++C PC+NGGTC + + C C
Sbjct: 565 SGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC 624
Query: 424 PFD-------------------------NLSRTFY-------GGRDCSDILLGCTHQQCL 451
P +L FY G+ C C C
Sbjct: 625 PSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCS 684
Query: 452 NNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLS 487
N GTC D F C CP G+ GS C +A S
Sbjct: 685 NGGTC----YDSGDTFRCACPPGWKGSTCAVAKNSS 716
Score = 194 bits (492), Expect = 7e-49
Identities = 131/484 (27%), Positives = 192/484 (39%), Gaps = 90/484 (18%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQ------ 80
C + C + C+N + C + D C+C D K+C ++PC C+
Sbjct: 495 CEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGG--KNCSVPREPCPGGACRVIDGCG 552
Query: 81 --------GSAT---------CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGG 123
G+A CV+ PG +F C C G++GT C I C C++GG
Sbjct: 553 SDAGPGMPGTAASGVCGPHGRCVSQPGG-NFSCICDSGFTGTYCHENIDDCLGQPCRNGG 611
Query: 124 ICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQ------------------------- 158
C + C CP+G+ G C+ + ++C PC
Sbjct: 612 TCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTC 671
Query: 159 -------------NGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE-CASDPCKNEATCLNE 204
NG C D D + C C PG++G C + + C +PC N TC+
Sbjct: 672 HSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGS 731
Query: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
++CIC + G C ++C PC NG C D + + C+CAPGF G C +N D
Sbjct: 732 GASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINID 791
Query: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPL---CWSKPC---HNNATCED 318
EC S PC +G CVD N Y C+C G G C+ ++ CWS+ H ++ ED
Sbjct: 792 ECQSSPCAYGATCVDEINGYRCSCP-PGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVED 850
Query: 319 SVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 378
+C C G + + C PC G+ LS++ G+ +A
Sbjct: 851 C---NSCRCLDG----RRDCSKVWCGWKPCLLAGQPEALSAQCPLGQ-------RCLEKA 896
Query: 379 SGYVCICQPGFTGIHCEEDVNECSSNPC-QNGGTCENLPGNYTCHCPFDNLSRTFYGGRD 437
G C+ P C E S PC G +N T H D++ + G
Sbjct: 897 PGQ-CLRPPCEAWGEC--GAEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAI 953
Query: 438 CSDI 441
CS I
Sbjct: 954 CSGI 957
Score = 177 bits (449), Expect = 6e-44
Identities = 77/195 (39%), Positives = 106/195 (54%), Gaps = 9/195 (4%)
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYH 1199
+ C SNPC +GG+C ++ S + C CP GWSG C L+IDEC SNPC G C D+V +
Sbjct: 349 HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
C C + G C++D+++C+ QC +G TC NGY C+C F G+ C R
Sbjct: 409 CICPEQWVGATCQLDVNDCRG-QCQHGGTCKDLVNGYQCVCPRGFGGRHCELER------ 461
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
+E + C++GG C + C C GF+G CE D+D C PC NG C +L +
Sbjct: 462 -DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDY 520
Query: 1320 QCLCDVAFAGERCEV 1334
C C F G+ C V
Sbjct: 521 YCACPDDFGGKNCSV 535
Score = 171 bits (433), Expect = 5e-42
Identities = 80/200 (40%), Positives = 113/200 (56%), Gaps = 11/200 (5%)
Query: 1140 LNVCNSN-PCLHGGNCEDIY-SSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVA 1196
LN C S+ PC +GG C + Y C+CP G+SG++CE C SNPC + G+C + +
Sbjct: 308 LNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPS 367
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
+ C C G++G C +DID C S+ CA G TC+ +G+ C+C + G C +L
Sbjct: 368 GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC---QLDV 424
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
C + C +GG C + +C+C GF G CE + DECAS PC +GGLC+DL
Sbjct: 425 NDCRGQ-----CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLA 479
Query: 1317 NKFQCLCDVAFAGERCEVDL 1336
+ F C C F+G CEVD+
Sbjct: 480 DGFHCHCPQGFSGPLCEVDV 499
Score = 169 bits (428), Expect = 2e-41
Identities = 83/221 (37%), Positives = 113/221 (51%), Gaps = 19/221 (8%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
L +N C C HGG C+D+ + Y C CP G+ G+HCEL DEC S+PC G C D
Sbjct: 422 LDVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD 480
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
+HC C G++G CEVD+D C+ C NGA C + Y C C +F GK C R P
Sbjct: 481 GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC 540
Query: 1257 TV--------CGNEK--------TNLTCYNGGNC-TEFQTELKCMCRPGFTGEWCEKDID 1299
CG++ + C G C ++ C+C GFTG +C ++ID
Sbjct: 541 PGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENID 600
Query: 1300 ECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
+C PC NGG C D ++ F+C C + GE C+ + D L
Sbjct: 601 DCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCL 641
Score = 159 bits (402), Expect = 2e-38
Identities = 84/259 (32%), Positives = 122/259 (47%), Gaps = 16/259 (6%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ C+ N CL + C + C D D C+C D K C + + C + C
Sbjct: 629 EGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKG--KTCHSREFQCDAYTCSNG 686
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETT-IGSCGKNSCQHGGICHQDPIYPVCICPAGYA 141
TC ++ +F C CPPG+ G+ C SC N C +GG C CIC G+
Sbjct: 687 GTCYDSGD--TFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE 744
Query: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
GR C + ++C PC NG +C DG++ + C C PG+ G C + +DEC S PC ATC
Sbjct: 745 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATC 804
Query: 202 LNEIGRYTCICPHNYSGVNCELEID---ECWSQ--PCLNGATCQDALGAYFCDCAPGFLG 256
++EI Y C CP +G C+ I CWS+ P +G++ + + C C G
Sbjct: 805 VDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS--CRCLDG--- 859
Query: 257 DHCELNTDECASQPCLHGG 275
+ + C +PCL G
Sbjct: 860 -RRDCSKVWCGWKPCLLAG 877
Score = 150 bits (380), Expect = 6e-36
Identities = 65/195 (33%), Positives = 97/195 (49%), Gaps = 7/195 (3%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYHCT 1201
C PC +GG C D ++ C CP GW G+ C+ N ++C +PC G C D V ++C
Sbjct: 602 CLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCA 661
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
C+ G+ G C C ++ C+NG TC + + C C + G C ++ S +
Sbjct: 662 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN- 720
Query: 1262 EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQC 1321
C NGG C C+CR G+ G C + ++C PC NGG+C D +N F+C
Sbjct: 721 -----PCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRC 775
Query: 1322 LCDVAFAGERCEVDL 1336
C FAG C +++
Sbjct: 776 ECAPGFAGPDCRINI 790
Score = 150 bits (379), Expect = 8e-36
Identities = 69/195 (35%), Positives = 97/195 (49%), Gaps = 9/195 (4%)
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYH 1199
N C +PC G C D+ + ++C+C GW GK C +C + C +G C D +
Sbjct: 638 NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 697
Query: 1200 CTCEPGYTGVNCEVDIDN-CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C PG+ G C V ++ C + C NG TC+ +SC+C + G+ C +
Sbjct: 698 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNT----- 752
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
N+ L CYNGG C + +C C PGF G C +IDEC S PC G C D +N
Sbjct: 753 --NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEING 810
Query: 1319 FQCLCDVAFAGERCE 1333
++C C AG RC+
Sbjct: 811 YRCSCPPGRAGPRCQ 825
Score = 142 bits (357), Expect = 3e-33
Identities = 67/179 (37%), Positives = 99/179 (55%), Gaps = 17/179 (9%)
Query: 1163 CSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSH 1221
C C GW G+ C DEC P C+HG+C V + C CE + G+ C+ D++ C SH
Sbjct: 262 CRCSYGWQGRFC----DECVPYPGCVHGSC---VEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 1222 Q-CANGATCIS-HTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQT 1279
C NG TCI+ + Y C C ++G+ C ++ + T+ C NGG+C E +
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAE-------HACTSNPCANGGSCHEVPS 367
Query: 1280 ELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
+C C G++G C DIDECAS+PC GG C D ++ F+C+C + G C++D+ D
Sbjct: 368 GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVND 426
Score = 109 bits (272), Expect = 2e-23
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 1/110 (0%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCT 1201
C NPC++GG C +S+ C C GW G+ C N ++C PC +G C D V + C
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 776
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
C PG+ G +C ++ID CQS CA GATC+ NGY C C G C++
Sbjct: 777 CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQE 826
Score = 101 bits (252), Expect = 4e-21
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 9/158 (5%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL-NIDECFSNPCIHGN-CSDRVAAYHC 1200
C++ C +GG C D ++ C+CP GW G C + C NPC++G C A++ C
Sbjct: 678 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSC 737
Query: 1201 TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG 1260
C G+ G C + ++C C NG C+ N + C C F G CR +
Sbjct: 738 ICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCR-------INI 790
Query: 1261 NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
+E + C G C + +C C PG G C++ I
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 828
Score = 65.1 bits (157), Expect = 5e-10
Identities = 29/75 (38%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGF 946
+++C SNPC NGG CH F C CP+ SG C ++ C +PC G C + GF
Sbjct: 348 EHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGF 407
Query: 947 ECIANAVFNGQSGQI 961
ECI + G + Q+
Sbjct: 408 ECICPEQWVGATCQL 422
Score = 61.2 bits (147), Expect = 7e-09
Identities = 28/71 (39%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S+PCH+GG+C D F C CP SG CE +V C SPC +GA+C + +
Sbjct: 462 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 521
Query: 948 CIANAVFNGQS 958
C F G++
Sbjct: 522 CACPDDFGGKN 532
Score = 58.2 bits (139), Expect = 6e-08
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPV 942
CA D + C SNPC GG C + D F C CP G C+ +V C C HG C+ +
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCR-GQCQHGGTCKDL 440
Query: 943 LQGFECIANAVFNGQ 957
+ G++C+ F G+
Sbjct: 441 VNGYQCVCPRGFGGR 455
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 889 NSCKSN-PCHNGGVC-HSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQG 945
N C S+ PC NGG C ++ D + C+CP SG+ CE+ + C +PC +G C V G
Sbjct: 309 NYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSG 368
Query: 946 FECIANAVFNG 956
FEC + ++G
Sbjct: 369 FECHCPSGWSG 379
Score = 52.0 bits (123), Expect = 4e-06
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C PC+NGG+C + F C C +G C + C SPC +GA C + G+
Sbjct: 753 NDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 812
Query: 948 C 948
C
Sbjct: 813 C 813
Score = 50.4 bits (119), Expect = 1e-05
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 2/69 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C+ C +GG C + + C CP G+ CE E C SPC G C+ + GF
Sbjct: 425 NDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 483
Query: 948 CIANAVFNG 956
C F+G
Sbjct: 484 CHCPQGFSG 492
Score = 46.6 bits (109), Expect = 2e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C PC NGG C D F C CP+ G+ C+ C PC +C ++ F
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 659
Query: 948 CIANAVFNGQS 958
C + + G++
Sbjct: 660 CACDDGWKGKT 670
Score = 46.6 bits (109), Expect = 2e-04
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ--WCGFSPCPHGAQCQPVLQGFEC 948
C + C NGG C+ D F C+CP G C + C +PC +G C F C
Sbjct: 678 CDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSC 737
Query: 949 IANAVFNGQS 958
I + G++
Sbjct: 738 ICRDGWEGRT 747
Score = 46.6 bits (109), Expect = 2e-04
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 882 TQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQ 940
T A ++SC NPC NGG C FSC C G+ C C PC +G C
Sbjct: 708 TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV 767
Query: 941 PVLQGFECIANAVFNGQSGQI 961
+ F C F G +I
Sbjct: 768 DGVNWFRCECAPGFAGPDCRI 788
Score = 45.4 bits (106), Expect = 4e-04
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQGFE 947
N C +PCH+ G C+ +DF C+C GK C ++ C C +G C F
Sbjct: 638 NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 697
Query: 948 CIANAVFNGQS 958
C + G +
Sbjct: 698 CACPPGWKGST 708
Score = 44.7 bits (104), Expect = 6e-04
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNID---ECFS--NPCIHGN 1190
+ ++ C S+PC +G C D + Y CSCP G +G C+ I C+S P HG+
Sbjct: 788 INIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGS 845
Score = 43.1 bits (100), Expect = 0.002
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV------QWCGFSPCPHGA 937
+ C+S+PC G C + + CSCP +G C+EV W +P PHG+
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGS 845
Score = 42.0 bits (97), Expect = 0.004
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGA 937
C+ +PC NG C++ D+ C+CP GK C + PCP GA
Sbjct: 502 CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPR----EPCPGGA 544
Score = 38.1 bits (87), Expect = 0.060
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D CE PC++ RC NL Y C C + G NC
Sbjct: 500 DLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNC 533
Score = 38.1 bits (87), Expect = 0.060
Identities = 31/123 (25%), Positives = 46/123 (37%), Gaps = 15/123 (12%)
Query: 843 LNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGD------NSCKSNPC 896
L G ++ C D N ++ P P V GC D + S C
Sbjct: 516 LEGDYYCACPDDFGGKNCSVPREPCPGGAC-------RVIDGCGSDAGPGMPGTAASGVC 568
Query: 897 HNGGVCHSR-WDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
G C S+ +FSC C + +G C E + C PC +G C + F C + +
Sbjct: 569 GPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW 628
Query: 955 NGQ 957
G+
Sbjct: 629 EGE 631
Score = 36.6 bits (83), Expect = 0.17
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ +D C S PC S G C +L + C C + + GP C
Sbjct: 459 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLC 495
Score = 34.7 bits (78), Expect = 0.66
Identities = 13/32 (40%), Positives = 17/32 (53%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC SRGRC +L + C C ++G C
Sbjct: 640 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTC 671
Score = 32.7 bits (73), Expect = 2.5
Identities = 11/32 (34%), Positives = 16/32 (50%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC + G C + ++C C + GP C
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382
Score = 32.3 bits (72), Expect = 3.3
Identities = 14/42 (33%), Positives = 18/42 (42%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGR 715
D C+S PC C++ Y+C C GP C GR
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 832
Score = 32.0 bits (71), Expect = 4.3
Identities = 13/34 (38%), Positives = 20/34 (58%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C QPC++ G CI+ +++C C +EG C
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 633
Score = 31.2 bits (69), Expect = 7.3
Identities = 11/34 (32%), Positives = 17/34 (50%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PC + G C++ ++C C + G C
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATC 420
Score = 30.8 bits (68), Expect = 9.6
Identities = 11/32 (34%), Positives = 15/32 (46%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PC + G C+ S+ C C +EG C
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTC 748
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 285 bits (728), Expect = 3e-76
Identities = 164/511 (32%), Positives = 227/511 (44%), Gaps = 105/511 (20%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDC-DNMKDPCFSNPCQGSATCVNTPGER 92
CLS C N TC D + C C + L DC + + D C C+ C+ G
Sbjct: 433 CLSAPCHNGGTCVDADQGYVCECPEGFMGL--DCRERVPDDC---ECRNGGRCL---GAN 484
Query: 93 SFLCKCPPGYSGTICETTIGS--CGKNS-CQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
+ LC+CP G+ G +CE I + C N+ C GG C + +C+C +
Sbjct: 485 TTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSL--P 542
Query: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD-LEVDECASDPCKNEATCLNEIGRY 208
C S PC NG C D Y+C C G+ G+HC+ C+S PC+N TC G Y
Sbjct: 543 SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEY 602
Query: 209 TCICPHNYSGVNCEL-EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECA 267
C CP+ ++G +CE+ + D C S PC NG TC +G Y CDC PGF G HCE+ C
Sbjct: 603 HCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCF 662
Query: 268 SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE---------------------------- 299
PC++GG C D + + C+C +G+ G C+
Sbjct: 663 RSPCVNGGTCEDRDTDFFCHCQ-AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVAL 721
Query: 300 ------------TLMPLC-----WSKP-------------CHNNATCEDSVDNYTCHCWP 329
+ + +C WS+P C + +C+D V Y C C
Sbjct: 722 YACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCST 781
Query: 330 GYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF 389
GY GA CE++ +EC ++PC++ G C L YVC C GF
Sbjct: 782 GYEGAHCELERDECRAHPCRNGGSCRNL--------------------PGAYVCRCPAGF 821
Query: 390 TGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQ 449
G+HCE +V+ C S+PCQ+GG CE+ G Y C CP +F+ G C + C
Sbjct: 822 VGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCP-----ESFF-GYHCETVSDPCFSSP 875
Query: 450 CLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
C G C+ +G H SC C GYTG C
Sbjct: 876 CGGRGYCLA--SNGSH--SCTCKVGYTGEDC 902
Score = 279 bits (713), Expect = 2e-74
Identities = 171/553 (30%), Positives = 223/553 (40%), Gaps = 124/553 (22%)
Query: 27 CNKNNTRCLS-NSCQNNSTCKD--FSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSA 83
C + CL+ C N C D + + +CS + + C + C S PCQ
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 84 TCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGR 143
TC T G SF C+CP G+ G CET C CQHGG C + VC+C AGY G
Sbjct: 325 TC--THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGA 382
Query: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL----EVDECASDPCKNEA 199
CE+D D+C+ PC NG C D + Y+C C ++G C+ D C S PC N
Sbjct: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
Query: 200 TCLNEIGRYTCICPHNYSGVNCELEI-DECWSQPCLNGATCQDALGAYFCDCAPGFLGDH 258
TC++ Y C CP + G++C + D+C C NG C A C C GF G
Sbjct: 443 TCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLGA-NTTLCQCPLGFFGLL 498
Query: 259 CE---------LNT------------------------------DECASQPCLHGGLCVD 279
CE +NT C S PC +GG C
Sbjct: 499 CEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDA 558
Query: 280 GENRYSCNCTGSGFTGTHCETLMP-LCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEI 338
++ Y+C C GF G HCE P LC S PC N TC+++ Y C C +TG CEI
Sbjct: 559 HDDSYTCECP-RGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI 617
Query: 339 DL-NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEED 397
+ C S PC + G C +H Y C C PGF+G HCE
Sbjct: 618 GKPDSCASGPCHNGGTC--------------------FHYIGKYKCDCPPGFSGRHCEIA 657
Query: 398 VNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDC-------------SDILLG 444
+ C +PC NGGTCE+ ++ CHC + R DC + LG
Sbjct: 658 PSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLG 717
Query: 445 CTHQQCLNNG----------TCIPH-------------------------FQDGQHGFSC 469
+ G C PH QD G+ C
Sbjct: 718 AVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLC 777
Query: 470 LCPSGYTGSLCEI 482
LC +GY G+ CE+
Sbjct: 778 LCSTGYEGAHCEL 790
Score = 250 bits (639), Expect = 6e-66
Identities = 151/437 (34%), Positives = 194/437 (44%), Gaps = 45/437 (10%)
Query: 82 SATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQD-----PIYPVCIC 136
+ T V PG +F G TT C +GG C D P Y C C
Sbjct: 241 TTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSY-TCSC 299
Query: 137 PAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
+G+ GR C +D +ECAS PCQNG C GI+ + C C G+ G C+ C + C+
Sbjct: 300 LSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQ 359
Query: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
+ C E G C+C Y+G CE+++D+C PCLNG +C D +G Y C CA F G
Sbjct: 360 HGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKG 419
Query: 257 DHCELN----TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHN 312
CE D C S PC +GG CVD + Y C C GF G C +P C N
Sbjct: 420 LRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECP-EGFMGLDCRERVP--DDCECRN 476
Query: 313 NATCEDSVDNYTCHCWPGYTGAQCEIDLN--ECNSN-PCQSNGECVELSS------EKQY 363
C + C C G+ G CE ++ CN N C G C+E +
Sbjct: 477 GGRCL-GANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDH 535
Query: 364 GRITGLPS-----------SFSYHEASGYVCICQPGFTGIHCEE-DVNECSSNPCQNGGT 411
LPS S H+ S Y C C GF G HCE+ + CSS PC+NGGT
Sbjct: 536 NASHSLPSPCDSDPCFNGGSCDAHDDS-YTCECPRGFHGKHCEKARPHLCSSGPCRNGGT 594
Query: 412 CENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLC 471
C+ G Y C CP+ R G+ S C C N GTC + + C C
Sbjct: 595 CKEAGGEYHCSCPYRFTGRHCEIGKPDS-----CASGPCHNGGTCFHYIGK----YKCDC 645
Query: 472 PSGYTGSLCEIATTLSF 488
P G++G CEIA + F
Sbjct: 646 PPGFSGRHCEIAPSPCF 662
Score = 234 bits (596), Expect = 6e-61
Identities = 133/389 (34%), Positives = 174/389 (44%), Gaps = 51/389 (13%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDP-CFSNPCQGSATCVNTPGER 92
C S+ C N +C C C + K C+ + C S PC+ TC GE
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHG--KHCEKARPHLCSSGPCRNGGTCKEAGGE- 601
Query: 93 SFLCKCPPGYSGTICETTIG---SCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
+ C CP ++G CE IG SC C +GG C C CP G++GR CEI
Sbjct: 602 -YHCSCPYRFTGRHCE--IGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAP 658
Query: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKN-----EATCLNE 204
C SPC NG C+D + C C GY GR C EVD + K+ T L
Sbjct: 659 SPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGA 718
Query: 205 IGRYTC-------------IC-PHN-YSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
+ Y C +C PH +S LEIDEC SQPCL+G +CQD + Y C
Sbjct: 719 VALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCL 778
Query: 250 CAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP 309
C+ G+ G HCEL DEC + PC +GG C + Y C C +GF G HCET + C S P
Sbjct: 779 CSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCP-AGFVGVHCETEVDACDSSP 837
Query: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGL 369
C + CE Y C C + G CE + C S+PC G C+ +
Sbjct: 838 CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGS--------- 888
Query: 370 PSSFSYHEASGYVCICQPGFTGIHCEEDV 398
+ C C+ G+TG C +++
Sbjct: 889 -----------HSCTCKVGYTGEDCAKEL 906
Score = 142 bits (359), Expect = 2e-33
Identities = 71/249 (28%), Positives = 106/249 (42%), Gaps = 53/249 (21%)
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL-NIDECFSNPCIH-GNCSDRVAAY 1198
++C+S PC +GG C++ YHCSCP ++G+HCE+ D C S PC + G C + Y
Sbjct: 582 HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKY 641
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ------- 1251
C C PG++G +CE+ C C NG TC + C C + G+ C+
Sbjct: 642 KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPP 701
Query: 1252 --------------------------------------------SRLPSTVCGNEKTNLT 1267
S P + +E +
Sbjct: 702 EEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQP 761
Query: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
C +GG+C + C+C G+ G CE + DEC + PC NGG C++L + C C F
Sbjct: 762 CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF 821
Query: 1328 AGERCEVDL 1336
G CE ++
Sbjct: 822 VGVHCETEV 830
Score = 138 bits (347), Expect = 4e-32
Identities = 70/201 (34%), Positives = 94/201 (46%), Gaps = 9/201 (4%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
L +N C S PC +GG C +S+ C CP G+ G CE C + C HG C
Sbjct: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENG 369
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
+ C C+ GYTG CE+D+D+C C NG +C+ Y+CLC F G C P
Sbjct: 370 SAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHP- 428
Query: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI-DECASDPCVNGGLCQDL 1315
+ + C+NGG C + C C GF G C + + D+C C NGG C
Sbjct: 429 --VPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG- 482
Query: 1316 LNKFQCLCDVAFAGERCEVDL 1336
N C C + F G CE ++
Sbjct: 483 ANTTLCQCPLGFFGLLCEFEI 503
Score = 137 bits (346), Expect = 6e-32
Identities = 64/165 (38%), Positives = 88/165 (53%), Gaps = 12/165 (7%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRV 1195
CL+++ C S PCLHGG+C+D + Y C C G+ G HCEL DEC ++PC + G+C +
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
AY C C G+ GV+CE ++D C S C +G C S Y C+C +F G C P
Sbjct: 811 GAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDP 870
Query: 1256 --STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
S+ CG G C C C+ G+TGE C K++
Sbjct: 871 CFSSPCGGR---------GYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 131 bits (329), Expect = 5e-30
Identities = 74/250 (29%), Positives = 99/250 (39%), Gaps = 66/250 (26%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHC- 1200
C S PC +GG C Y C CP G+SG+HCE+ CF +PC++G C DR + C
Sbjct: 623 CASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCH 682
Query: 1201 ----------------------------------------TCEPGYT------------- 1207
C+ GY+
Sbjct: 683 CQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPH 742
Query: 1208 GVNCE----VDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEK 1263
GV E ++ID C+S C +G +C GY CLC + G C R +E
Sbjct: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER-------DEC 795
Query: 1264 TNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLC 1323
C NGG+C C C GF G CE ++D C S PC +GG C+ + C+C
Sbjct: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
Query: 1324 DVAFAGERCE 1333
+F G CE
Sbjct: 856 PESFFGYHCE 865
Score = 130 bits (328), Expect = 7e-30
Identities = 65/187 (34%), Positives = 87/187 (46%), Gaps = 40/187 (21%)
Query: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGY 1206
PCL+GG C D C+ GN S Y C+C G+
Sbjct: 277 PCLNGGKCID----------------------------DCVTGNPS-----YTCSCLSGF 303
Query: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
TG C +D++ C S C NG TC N + C C F G C ++ P C ++
Sbjct: 304 TGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSP---CDTKE--- 357
Query: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVA 1326
C +GG C C+C+ G+TG CE D+D+C+ DPC+NGG C DL+ + CLC
Sbjct: 358 -CQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP 416
Query: 1327 FAGERCE 1333
F G RCE
Sbjct: 417 FKGLRCE 423
Score = 129 bits (325), Expect = 2e-29
Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 11/197 (5%)
Query: 1143 CNSNP-CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAYHC 1200
CN N C GG C + SY C C + H + C S+PC +G +C +Y C
Sbjct: 508 CNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS--PCDSDPCFNGGSCDAHDDSYTC 565
Query: 1201 TCEPGYTGVNCEVDIDN-CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
C G+ G +CE + C S C NG TC Y C C FTG+ C + S
Sbjct: 566 ECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCAS 625
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
G C+NGG C + + KC C PGF+G CE C PCVNGG C+D F
Sbjct: 626 G------PCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 1320 QCLCDVAFAGERCEVDL 1336
C C + G RC+ ++
Sbjct: 680 FCHCQAGYMGRRCQAEV 696
Score = 127 bits (318), Expect = 1e-28
Identities = 73/219 (33%), Positives = 92/219 (42%), Gaps = 15/219 (6%)
Query: 1120 PQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLG-WSGKHCELNI 1178
P+E + + N G + L C+ L S P G WS L I
Sbjct: 701 PEEVKHATLRFNGTRLGAVALYACDRGYSLSAP------SRIRVCQPHGVWSEPPQCLEI 754
Query: 1179 DECFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYS 1237
DEC S PC+HG +C DRVA Y C C GY G +CE++ D C++H C NG +C + Y
Sbjct: 755 DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 814
Query: 1238 CLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKD 1297
C C F G C C + C +GG C C+C F G CE
Sbjct: 815 CRCPAGFVGVHCETE---VDACDSSP----CQHGGRCESGGGAYLCVCPESFFGYHCETV 867
Query: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
D C S PC G C C C V + GE C +L
Sbjct: 868 SDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 121 bits (304), Expect = 4e-27
Identities = 71/249 (28%), Positives = 103/249 (41%), Gaps = 53/249 (21%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI----DECFSNPCIHGN-CS 1192
+ ++ C+ +PCL+GG+C D+ +Y C C + G CE D C S PC +G C
Sbjct: 386 MDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCV 445
Query: 1193 DRVAAYHCTCEPGYTGVNCEVDI-DNCQSH------------------------------ 1221
D Y C C G+ G++C + D+C+
Sbjct: 446 DADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITA 505
Query: 1222 -------QCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC 1274
QC +G C+ H Y C+C + LPS C ++ C+NGG+C
Sbjct: 506 MPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS----LPSP-CDSDP----CFNGGSC 556
Query: 1275 TEFQTELKCMCRPGFTGEWCEKDIDE-CASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
C C GF G+ CEK C+S PC NGG C++ ++ C C F G CE
Sbjct: 557 DAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCE 616
Query: 1334 VDLADDLIS 1342
+ D S
Sbjct: 617 IGKPDSCAS 625
Score = 69.3 bits (168), Expect = 2e-11
Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 4/123 (3%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ + C C ++ C+N +C++ C C A + C+ D C S+PCQ
Sbjct: 784 EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRC--PAGFVGVHCETEVDACDSSPCQHG 841
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
C + G ++LC CP + G CET C + C G C C C GY G
Sbjct: 842 GRCES--GGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTG 899
Query: 143 RFC 145
C
Sbjct: 900 EDC 902
Score = 60.5 bits (145), Expect = 1e-08
Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW-CGFSPCPHGAQCQPVLQGFE 947
N C S PC NGG C + F C CPA G CE Q C C HG QCQ
Sbjct: 313 NECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV 372
Query: 948 CIANAVFNG 956
C+ A + G
Sbjct: 373 CVCQAGYTG 381
Score = 56.6 bits (135), Expect = 2e-07
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C+++PC NGG C + + C CPA G CE EV C SPC HG +C+ +
Sbjct: 793 DECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYL 852
Query: 948 CIANAVFNG 956
C+ F G
Sbjct: 853 CVCPESFFG 861
Score = 55.5 bits (132), Expect = 4e-07
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ--WCGFSPCPHGAQCQPVLQGFEC 948
C S+PC NGG C + D ++C CP GK CE+ + C PC +G C+ + C
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHC 604
Query: 949 IANAVFNGQSGQI 961
F G+ +I
Sbjct: 605 SCPYRFTGRHCEI 617
Score = 55.5 bits (132), Expect = 4e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+SC S PCHNGG C + C CP SG+ CE C SPC +G C+ F
Sbjct: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFF 680
Query: 948 CIANAVFNGQSGQ 960
C A + G+ Q
Sbjct: 681 CHCQAGYMGRRCQ 693
Score = 54.7 bits (130), Expect = 6e-07
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--EVQWCGFSPCPHGAQCQPVLQGFEC 948
C S PC NGG C ++ CSCP +G+ CE + C PC +G C + ++C
Sbjct: 584 CSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKC 643
Query: 949 IANAVFNGQSGQI 961
F+G+ +I
Sbjct: 644 DCPPGFSGRHCEI 656
Score = 54.3 bits (129), Expect = 8e-07
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 11/87 (12%)
Query: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPC-----KNEATCLNEIG 206
C+ +PCQNG C G D +SC C PG++GR C+L + S PC + +A + E G
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCTRLFSETKAFPVWEGG 1369
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPC 233
+C H Y V + D C+ + C
Sbjct: 1370 ----VCHHVYKRV-YRVHQDICFKESC 1391
Score = 47.8 bits (112), Expect = 8e-05
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 3/95 (3%)
Query: 65 KDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGI 124
KD N+ C NPCQ TCV PG + C C PG+ G CE + +
Sbjct: 1302 KDIGNVPGNCSENPCQNGGTCV--PGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSE 1359
Query: 125 CHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQN 159
P++ +C Y R + D C C++
Sbjct: 1360 TKAFPVWEGGVCHHVYK-RVYRVHQDICFKESCES 1393
Score = 47.8 bits (112), Expect = 8e-05
Identities = 21/44 (47%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPC 271
C PC NG TC A+ CDC PGF G CEL + S+PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVL 943
C + C+S PC +GG C R + C C G CE E C PC +G C+ +
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLP 810
Query: 944 QGFECIANAVFNG 956
+ C A F G
Sbjct: 811 GAYVCRCPAGFVG 823
Score = 45.8 bits (107), Expect = 3e-04
Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 266 CASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC 310
C+ PC +GG CV G + +SC+C G GF G CE L + S+PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDC-GPGFKGRRCE-LACIKVSRPC 1353
Score = 44.7 bits (104), Expect = 6e-04
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
C + C +GG C C C A +G ACE +V C PC +G C ++ + C+
Sbjct: 353 CDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCL 412
Query: 950 ANAVFNG 956
F G
Sbjct: 413 CAEPFKG 419
Score = 43.1 bits (100), Expect = 0.002
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPC 348
C PC N TC D ++C C PG+ G +CE+ + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
Score = 42.4 bits (98), Expect = 0.003
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 1/70 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV-QWCGFSPCPHGAQCQPVLQGFE 947
++C S+PC +GG C S + C CP G CE V C SPC C
Sbjct: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHS 890
Query: 948 CIANAVFNGQ 957
C + G+
Sbjct: 891 CTCKVGYTGE 900
Score = 42.4 bits (98), Expect = 0.003
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
+G +D ++ C+ C N GTC+P G SC C G+ G CE+A
Sbjct: 1299 HGSKDIGNVPGNCSENPCQNGGTCVP----GADAHSCDCGPGFKGRRCELA 1345
Score = 42.0 bits (97), Expect = 0.004
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 895 PCHNGGVCHSRW----DDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
PC NGG C ++CSC + +G+ C +V C PC +G C + F C
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQ 336
Query: 950 ANAVFNG 956
A F G
Sbjct: 337 CPAGFGG 343
Score = 41.6 bits (96), Expect = 0.005
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 5/73 (6%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-----VQWCGFSPCPHGAQCQPVL 943
+ C +PC NGG C +++C C G CE C +PC +G C
Sbjct: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 448
Query: 944 QGFECIANAVFNG 956
QG+ C F G
Sbjct: 449 QGYVCECPEGFMG 461
Score = 40.4 bits (93), Expect = 0.012
Identities = 17/39 (43%), Positives = 20/39 (51%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCG 929
C +PC NGG C R DF C C A G+ C+ CG
Sbjct: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCG 699
Score = 40.4 bits (93), Expect = 0.012
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC 1186
C+ NPC +GG C ++ C C G+ G+ CEL + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 39.7 bits (91), Expect = 0.021
Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 1217 NCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRL----PSTVCGNEKTNLTCYNGG 1272
NC + C NG TC+ + +SC C F G+ C + + P T +E + GG
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 1273 NC 1274
C
Sbjct: 1370 VC 1371
Score = 38.5 bits (88), Expect = 0.046
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
++C S PCHNGG C + C CP G C E + C +G +C
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE-RVPDDCECRNGGRC 480
Score = 38.1 bits (87), Expect = 0.060
Identities = 16/38 (42%), Positives = 19/38 (50%)
Query: 670 CVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C+ D C SQPC G C + Y C C YEG +C
Sbjct: 751 CLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC 788
Score = 38.1 bits (87), Expect = 0.060
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE 923
+C NPC NGG C D SC C G+ CE
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 37.4 bits (85), Expect = 0.10
Identities = 14/32 (43%), Positives = 19/32 (59%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C SQPCQ+ G C + S++C C + GP C
Sbjct: 315 CASQPCQNGGTCTHGINSFRCQCPAGFGGPTC 346
Score = 37.0 bits (84), Expect = 0.13
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 1301 CASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
C+ +PC NGG C + C C F G RCE+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 36.2 bits (82), Expect = 0.23
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 14/88 (15%)
Query: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPC 1306
V GN N C NGG C C C PGF G CE + E + P
Sbjct: 1307 VPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPV 1365
Query: 1307 VNGGLCQDLLNK-FQCLCDVAFAGERCE 1333
GG+C + + ++ D+ F E CE
Sbjct: 1366 WEGGVCHHVYKRVYRVHQDICFK-ESCE 1392
Score = 35.4 bits (80), Expect = 0.39
Identities = 13/34 (38%), Positives = 19/34 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C PC + G C++L +Y C C P++G C
Sbjct: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRC 422
Score = 35.4 bits (80), Expect = 0.39
Identities = 13/23 (56%), Positives = 15/23 (65%)
Query: 401 CSSNPCQNGGTCENLPGNYTCHC 423
CS NPCQNGGTC ++C C
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDC 1333
Score = 35.0 bits (79), Expect = 0.51
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 672 RKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ D C S PC + G C + Y+CDC + G +C
Sbjct: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHC 654
Score = 34.7 bits (78), Expect = 0.66
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
+ +D C + PC++ G C NL +Y C C + G +C E
Sbjct: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETE 829
Score = 34.7 bits (78), Expect = 0.66
Identities = 15/37 (40%), Positives = 19/37 (51%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
D C S PC RG C+ S+ C C Y G +C +E
Sbjct: 869 DPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
Score = 34.3 bits (77), Expect = 0.87
Identities = 22/84 (26%), Positives = 29/84 (34%), Gaps = 31/84 (36%)
Query: 343 CNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE------- 395
C+ NPCQ+ G CV A + C C PGF G CE
Sbjct: 1311 CSENPCQNGGTCVP--------------------GADAHSCDCGPGFKGRRCELACIKVS 1350
Query: 396 ----EDVNECSSNPCQNGGTCENL 415
+E + P GG C ++
Sbjct: 1351 RPCTRLFSETKAFPVWEGGVCHHV 1374
Score = 33.9 bits (76), Expect = 1.1
Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 1/34 (2%)
Query: 1181 CFSNPCIHGN-CSDRVAAYHCTCEPGYTGVNCEV 1213
C NPC +G C A+ C C PG+ G CE+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 33.5 bits (75), Expect = 1.5
Identities = 14/34 (41%), Positives = 19/34 (55%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C+S PCQ GRC + +Y C C + G +C
Sbjct: 831 DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHC 864
Score = 33.1 bits (74), Expect = 1.9
Identities = 13/32 (40%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C+S PC + G C SY C+C R + G +C
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC 576
Score = 32.7 bits (73), Expect = 2.5
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PC + G C++ Y C+C + G +C
Sbjct: 431 DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDC 464
Score = 32.0 bits (71), Expect = 4.3
Identities = 11/32 (34%), Positives = 17/32 (53%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C PCQ+ G C+ ++ CDC ++G C
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 31.2 bits (69), Expect = 7.3
Identities = 21/86 (24%), Positives = 30/86 (34%), Gaps = 12/86 (13%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAG----------RFGQDDSTGYV 725
C PC + G C + + C C Y G C E G RF
Sbjct: 661 CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA 720
Query: 726 IFTLDESYGDTISLSMFVRTLQPSGL 751
++ D Y ++S +R QP G+
Sbjct: 721 LYACDRGY--SLSAPSRIRVCQPHGV 744
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 251 bits (640), Expect = 5e-66
Identities = 109/227 (48%), Positives = 138/227 (60%), Gaps = 3/227 (1%)
Query: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV 133
CF NPC S TC R ++C CP GY+G CET I C C + G+C +
Sbjct: 1197 CFFNPCHNSGTCQQLG--RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 134 CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD 193
C CP+GY G+ CE + +EC+SSPC N +C DG+ GY C CV G+ G HC+ EV+EC S+
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 194 PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPG 253
PC N A C +++G + C CP + G C +DEC SQPC NGATC+D ++ C CA G
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAG 1374
Query: 254 FLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCET 300
F G HCELN +EC S PC + CVD N YSC C GF+G CET
Sbjct: 1375 FTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQ-PGFSGKRCET 1420
Score = 236 bits (603), Expect = 9e-62
Identities = 132/390 (33%), Positives = 188/390 (48%), Gaps = 66/390 (16%)
Query: 189 ECASDPCKNEATCLNEIGR-YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
EC +PC N TC ++GR Y C+CP Y+G+ CE +IDEC PCLN C+D +G +
Sbjct: 1196 ECFFNPCHNSGTC-QQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
C+C G+ G CE N +EC+S PCL+ G+CVDG Y C C GF G HCET + C S
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCV-KGFVGLHCETEVNECQS 1313
Query: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRIT 367
PC NNA CED V + C C PG+ G +C +++EC S PC++ C +
Sbjct: 1314 NPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKD----------- 1362
Query: 368 GLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDN 427
A+ + C+C GFTG HCE ++NEC SNPC+N TC + +Y+C C
Sbjct: 1363 ---------GANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKC---- 1409
Query: 428 LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLS 487
+ + G+ C T Q + G + G +G+ L G SL + T
Sbjct: 1410 --QPGFSGKRCE------TEQ---STGFNLDFEVSGIYGYVML--DGMLPSLHALTCT-- 1454
Query: 488 FEGDGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQ 547
W+KS G+ + A+ + + LL+ Y +
Sbjct: 1455 ------FWMKSSDDMNYGTPISYAVDNGSDNTL----------------LLTDYNGWVLY 1492
Query: 548 VNNQSKVLLFISHNTSDGEWHFVEVIFAEA 577
VN + K+ S N DG WH + + + A
Sbjct: 1493 VNGREKITNCPSVN--DGRWHHIAITWTSA 1520
Score = 230 bits (586), Expect = 8e-60
Identities = 100/247 (40%), Positives = 133/247 (53%), Gaps = 21/247 (8%)
Query: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 210
EC +PC N CQ GY C C GY G C+ ++DEC+ PC N C + +G + C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270
CP Y+G CE I+EC S PCLN C D + Y C C GF+G HCE +EC S P
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330
CL+ +C D + C C GF GT C + C S+PC N ATC+D +++ C C G
Sbjct: 1316 CLNNAVCEDQVGGFLCKCP-PGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAG 1374
Query: 331 YTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390
+TG+ CE+++NEC SNPC++ CV+ E + Y C CQPGF+
Sbjct: 1375 FTGSHCELNINECQSNPCRNQATCVD--------------------ELNSYSCKCQPGFS 1414
Query: 391 GIHCEED 397
G CE +
Sbjct: 1415 GKRCETE 1421
Score = 209 bits (531), Expect = 2e-53
Identities = 94/227 (41%), Positives = 121/227 (53%), Gaps = 4/227 (1%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
C N C N+ TC+ + C C L C+ D C PC + C + GE
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGL--KCETDIDECSPLPCLNNGVCKDLVGE-- 1252
Query: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
F+C+CP GY+G CE I C + C + GIC C C G+ G CE + +EC
Sbjct: 1253 FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1312
Query: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICP 213
S+PC N AVC+D + G+ C C PG+ G C VDEC S PCKN ATC + + C+C
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372
Query: 214 HNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
++G +CEL I+EC S PC N ATC D L +Y C C PGF G CE
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 182 bits (463), Expect = 2e-45
Identities = 78/197 (39%), Positives = 114/197 (57%), Gaps = 8/197 (4%)
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAY 1198
++ C+ PCL+ G C+D+ + C CP G++G+ CE NI+EC S+PC++ G C D VA Y
Sbjct: 1232 IDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGY 1291
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
CTC G+ G++CE +++ CQS+ C N A C G+ C C F G C ++
Sbjct: 1292 RCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNV----- 1346
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
+E + C NG C + +C+C GFTG CE +I+EC S+PC N C D LN
Sbjct: 1347 --DECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNS 1404
Query: 1319 FQCLCDVAFAGERCEVD 1335
+ C C F+G+RCE +
Sbjct: 1405 YSCKCQPGFSGKRCETE 1421
Score = 177 bits (449), Expect = 6e-44
Identities = 127/395 (32%), Positives = 171/395 (43%), Gaps = 52/395 (13%)
Query: 96 CK-CPPG-YSGTICETTIGSCGKNSCQHGGICHQDPIYPVC-ICPAG-YAGRFCEIDHDE 151
CK CP G Y+ I I C K C+ G + C CP G Y +F
Sbjct: 1032 CKLCPSGMYTEYIHSRNISDC-KAQCKQGTYSYSG--LETCESCPLGTYQPKF---GSRS 1085
Query: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCI 211
C S P +N + + G S VP +G+ + C PC + N +
Sbjct: 1086 CLSCP-ENTSTVKRGAVNISACGVPCPEGKFSRSGLMPC--HPCPRDYYQPNAGKAFCLA 1142
Query: 212 CP-HNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD---ECA 267
CP + + I EC S +T A + + G + E+++ EC
Sbjct: 1143 CPFYGTTPFAGSRSITECSSF----SSTFSAAEESVVPPASLGHIKKRHEISSQVFHECF 1198
Query: 268 SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHC 327
PC + G C Y C C G+TG CET + C PC NN C+D V + C C
Sbjct: 1199 FNPCHNSGTCQQLGRGYVCLCP-LGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICEC 1257
Query: 328 WPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQP 387
GYTG +CE ++NEC+S+PC + G CV+ +GY C C
Sbjct: 1258 PSGYTGQRCEENINECSSSPCLNKGICVD--------------------GVAGYRCTCVK 1297
Query: 388 GFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTH 447
GF G+HCE +VNEC SNPC N CE+ G + C CP L G C + C
Sbjct: 1298 GFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFL------GTRCGKNVDECLS 1351
Query: 448 QQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Q C N TC +DG + F CLC +G+TGS CE+
Sbjct: 1352 QPCKNGATC----KDGANSFRCLCAAGFTGSHCEL 1382
Score = 171 bits (434), Expect = 3e-42
Identities = 78/195 (40%), Positives = 99/195 (50%), Gaps = 8/195 (4%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAAYHCT 1201
C NPC + G C+ + Y C CPLG++G CE +IDEC PC++ G C D V + C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICE 1256
Query: 1202 CEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
C GYTG CE +I+ C S C N C+ GY C C F G C N
Sbjct: 1257 CPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV-------N 1309
Query: 1262 EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQC 1321
E + C N C + C C PGF G C K++DEC S PC NG C+D N F+C
Sbjct: 1310 ECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRC 1369
Query: 1322 LCDVAFAGERCEVDL 1336
LC F G CE+++
Sbjct: 1370 LCAAGFTGSHCELNI 1384
Score = 169 bits (427), Expect = 2e-41
Identities = 72/198 (36%), Positives = 104/198 (52%), Gaps = 4/198 (2%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C C NN CKD + C C + + C+ + C S+PC CV
Sbjct: 1228 CETDIDECSPLPCLNNGVCKDLVGEFICECP--SGYTGQRCEENINECSSSPCLNKGICV 1285
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ G + C C G+ G CET + C N C + +C +C CP G+ G C
Sbjct: 1286 D--GVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG 1343
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
+ DEC S PC+NGA C+DG + + C C G+ G HC+L ++EC S+PC+N+ATC++E+
Sbjct: 1344 KNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELN 1403
Query: 207 RYTCICPHNYSGVNCELE 224
Y+C C +SG CE E
Sbjct: 1404 SYSCKCQPGFSGKRCETE 1421
Score = 124 bits (310), Expect = 8e-28
Identities = 51/112 (45%), Positives = 68/112 (60%), Gaps = 1/112 (0%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAA 1197
++N C SNPCL+ CED + C CP G+ G C N+DEC S PC +G C D +
Sbjct: 1307 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANS 1366
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFC 1249
+ C C G+TG +CE++I+ CQS+ C N ATC+ N YSC C F+GK C
Sbjct: 1367 FRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 71.2 bits (173), Expect = 6e-12
Identities = 42/107 (39%), Positives = 54/107 (50%), Gaps = 14/107 (13%)
Query: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGY 1206
PC +GG C+ + CSCP GW G+ CE I C PC++G VA Y C C PG+
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCEEPI--CIL-PCLNGGRC--VAPYQCDCPPGW 3526
Query: 1207 TGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR 1253
TG C + CQS C NG C+ C C ++TG C + R
Sbjct: 3527 TGSRCHTAV--CQS-PCLNGGKCVRPNR---CHCLSSWTGHNCSRKR 3567
Score = 67.4 bits (163), Expect = 9e-11
Identities = 49/189 (25%), Positives = 80/189 (42%), Gaps = 23/189 (12%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S PC NG C + F C C A +G CE + C +PC + A C L +
Sbjct: 1347 DECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYS 1406
Query: 948 CIANAVFNGQSGQILFRSNGNITRELTNITFGFRTRDANVIILHA------EKEPEFLNI 1001
C F+G+ + + N+ E++ I +G+ D + LHA K + +N
Sbjct: 1407 CKCQPGFSGKRCETEQSTGFNLDFEVSGI-YGYVMLDGMLPSLHALTCTFWMKSSDDMNY 1465
Query: 1002 SI---------QDSRLFFQLQSGNSFYM---LSLTSLQSVNDGTWHEVTLSMTDPLSQTS 1049
D+ L +G Y+ +T+ SVNDG WH + ++ T S
Sbjct: 1466 GTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWT---SANG 1522
Query: 1050 RWQMEVDNE 1058
W++ +D +
Sbjct: 1523 IWKVYIDGK 1531
Score = 64.3 bits (155), Expect = 8e-10
Identities = 43/105 (40%), Positives = 52/105 (49%), Gaps = 16/105 (15%)
Query: 194 PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPG 253
PC+N C C CP + G CE I PCLNG C + Y CDC PG
Sbjct: 3475 PCQNGGICQRP---NACSCPEGWMGRLCEEPI---CILPCLNGGRC---VAPYQCDCPPG 3525
Query: 254 FLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHC 298
+ G C +T C S PCL+GG CV NR C+C S +TG +C
Sbjct: 3526 WTGSRC--HTAVCQS-PCLNGGKCV-RPNR--CHCL-SSWTGHNC 3563
Score = 64.3 bits (155), Expect = 8e-10
Identities = 38/103 (36%), Positives = 48/103 (46%), Gaps = 15/103 (14%)
Query: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGY 178
CQ+GGIC + C CP G+ GR CE + PC NG C + Y C C PG+
Sbjct: 3476 CQNGGICQRPN---ACSCPEGWMGRLCE---EPICILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 179 QGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNC 221
G C V C S PC N C+ C C +++G NC
Sbjct: 3527 TGSRCHTAV--CQS-PCLNGGKCVRP---NRCHCLSSWTGHNC 3563
Score = 62.8 bits (151), Expect = 2e-09
Identities = 40/105 (38%), Positives = 49/105 (46%), Gaps = 16/105 (15%)
Query: 232 PCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGS 291
PC NG CQ C C G++G CE + PCL+GG CV Y C+C
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCE---EPICILPCLNGGRCVAP---YQCDCP-P 3524
Query: 292 GFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC 336
G+TG+ C T + C S PC N C V CHC +TG C
Sbjct: 3525 GWTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 59.3 bits (142), Expect = 3e-08
Identities = 35/104 (33%), Positives = 47/104 (45%), Gaps = 15/104 (14%)
Query: 156 PCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHN 215
PCQNG +CQ +C C G+ GR C+ + PC N C + Y C CP
Sbjct: 3475 PCQNGGICQ---RPNACSCPEGWMGRLCE---EPICILPCLNGGRC---VAPYQCDCPPG 3525
Query: 216 YSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC 259
++G C + C S PCLNG C + C C + G +C
Sbjct: 3526 WTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 54.3 bits (129), Expect = 8e-07
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 13/86 (15%)
Query: 270 PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWP 329
PC +GG+C + +C+C G+ G CE P+C PC N C V Y C C P
Sbjct: 3475 PCQNGGIC---QRPNACSCP-EGWMGRLCEE--PIC-ILPCLNGGRC---VAPYQCDCPP 3524
Query: 330 GYTGAQCEIDLNECNSNPCQSNGECV 355
G+TG++C + C S PC + G+CV
Sbjct: 3525 GWTGSRCHTAV--CQS-PCLNGGKCV 3547
Score = 51.2 bits (121), Expect = 7e-06
Identities = 34/110 (30%), Positives = 47/110 (42%), Gaps = 22/110 (20%)
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELK 1282
C NG C +C C + G+ C + +C L C NGG C +
Sbjct: 3476 CQNGGIC---QRPNACSCPEGWMGRLCEEP-----IC-----ILPCLNGGRCV---APYQ 3519
Query: 1283 CMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
C C PG+TG C + C S PC+NGG C + +C C ++ G C
Sbjct: 3520 CDCPPGWTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNC 3563
Score = 50.4 bits (119), Expect = 1e-05
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
+ C PC N GVC +F C CP+ +G+ CEE + C SPC + C + G+
Sbjct: 1233 DECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYR 1292
Query: 948 CIANAVFNG 956
C F G
Sbjct: 1293 CTCVKGFVG 1301
Score = 48.9 bits (115), Expect = 3e-05
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C NPCHN G C + C CP +G CE ++ C PC + C+ ++ F
Sbjct: 1195 HECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 948 CIANAVFNGQ 957
C + + GQ
Sbjct: 1255 CECPSGYTGQ 1264
Score = 48.1 bits (113), Expect = 6e-05
Identities = 42/151 (27%), Positives = 54/151 (35%), Gaps = 39/151 (25%)
Query: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYT 332
+ G ++G R C G+ + C + PC N C+ C C G+
Sbjct: 3443 YSGYMLEGFLRSVCLENGTWTSPPICRAVCRF----PCQNGGICQRP---NACSCPEGWM 3495
Query: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGI 392
G CE + PC + G CV + Y C C PG+TG
Sbjct: 3496 GRLCEEPICIL---PCLNGGRCV-----------------------APYQCDCPPGWTGS 3529
Query: 393 HCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
C V C S PC NGG C P CHC
Sbjct: 3530 RCHTAV--CQS-PCLNGGKCVR-PNR--CHC 3554
Score = 47.8 bits (112), Expect = 8e-05
Identities = 19/38 (50%), Positives = 23/38 (60%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCE 1175
L +N C SNPC + C D +SY C C G+SGK CE
Sbjct: 1382 LNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
N C S+PC N G+C + C+C G CE EV C +PC + A C+ + GF
Sbjct: 1271 NECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFL 1330
Query: 948 C 948
C
Sbjct: 1331 C 1331
Score = 46.6 bits (109), Expect = 2e-04
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKC 98
CQN C+ + N CSC + + + C+ +P PC CV + C C
Sbjct: 3476 CQNGGICQ---RPNACSCPE--GWMGRLCE---EPICILPCLNGGRCV-----APYQCDC 3522
Query: 99 PPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC 145
PPG++G+ C T + C ++ C +GG C + C C + + G C
Sbjct: 3523 PPGWTGSRCHTAV--C-QSPCLNGGKCVRP---NRCHCLSSWTGHNC 3563
Score = 45.8 bits (107), Expect = 3e-04
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 19/83 (22%)
Query: 405 PCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 464
PCQNGG C+ C CP + GR C + + C CLN G C+ +Q
Sbjct: 3475 PCQNGGICQR---PNACSCPEG------WMGRLCEEPI--CI-LPCLNGGRCVAPYQ--- 3519
Query: 465 HGFSCLCPSGYTGSLCEIATTLS 487
C CP G+TGS C A S
Sbjct: 3520 ----CDCPPGWTGSRCHTAVCQS 3538
Score = 43.1 bits (100), Expect = 0.002
Identities = 16/37 (43%), Positives = 22/37 (59%)
Query: 1300 ECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
EC +PC N G CQ L + CLC + + G +CE D+
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDI 1232
Score = 37.4 bits (85), Expect = 0.10
Identities = 54/222 (24%), Positives = 79/222 (35%), Gaps = 39/222 (17%)
Query: 195 CKNEATCLNEIGRYTCICPHNYSGVNCE-LEIDECW-SQPCLNGATCQDALGAYFCDCAP 252
C N L + R C +++GV+ L++DEC C A+C + G+Y C C P
Sbjct: 1716 CNNGYYLLGD-SRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1774
Query: 253 GFLGD--HCELNTDECASQPCLHGG------LCVDGENRYSC------------NCTGSG 292
+ GD +C +C + G V E +SC C SG
Sbjct: 1775 PYTGDGKNC-AEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESG 1833
Query: 293 FTGTHCETLMPLCWSKPCHNNATCEDSV---------DNYTCHCWPGYTGAQCEIDLNEC 343
L+P C + C A E+ T C GYT A +
Sbjct: 1834 ----EWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLA 1889
Query: 344 NSNPCQSNGEC--VELSSEKQYGRITGLPSSFSYHEASGYVC 383
NS+ S C V+ SS + + S +Y + Y C
Sbjct: 1890 NSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSC 1931
Score = 37.0 bits (84), Expect = 0.13
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 895 PCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
PC NGG+C +CSCP G+ CEE PC +G +C
Sbjct: 3475 PCQNGGICQR---PNACSCPEGWMGRLCEEP--ICILPCLNGGRC 3514
Score = 36.6 bits (83), Expect = 0.17
Identities = 13/39 (33%), Positives = 20/39 (51%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAG 714
C+S PC+++ C++ SY C C + G C E G
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTG 1425
Score = 35.8 bits (81), Expect = 0.30
Identities = 48/205 (23%), Positives = 72/205 (35%), Gaps = 54/205 (26%)
Query: 316 CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNG------ECVELSSEKQYGRITGL 369
C ++ C C GY G + + C S + G C+ E T
Sbjct: 296 CGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENH----TSP 351
Query: 370 PSSFSYHEASGYVCICQPGF--TGIHCEEDVNECSSNPCQNGGTCENLPGNY-------T 420
P S S + C+C+ G+ +G CE V+ + P +NG +N N+
Sbjct: 352 PGSTSPED-----CVCREGYRASGQTCEL-VHCPALKPPENGYFIQNTCNNHFNAACGVR 405
Query: 421 CHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNG------------TCIPHFQDGQHG-F 467
CH FD L+G + CL NG TC PH + +HG
Sbjct: 406 CHPGFD---------------LVGSSIILCLPNGLWSGSESYCRVRTC-PHLRQPKHGHI 449
Query: 468 SCLCPSGYTGSLCEIATTLSFEGDG 492
SC + C +A + +G
Sbjct: 450 SCSTREMLYKTTCLVACDEGYRLEG 474
Score = 34.7 bits (78), Expect = 0.66
Identities = 14/51 (27%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 54 CSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSG 104
C+ + + N + C ++ + + C A+C+N G S++C C P Y+G
Sbjct: 1730 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDG--SYICSCVPPYTG 1778
Score = 34.3 bits (77), Expect = 0.87
Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 33/150 (22%)
Query: 115 GKNSCQHGGICH--QDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSC 172
GK+ C G C + CIC GY G+ + EC + C +G +G G
Sbjct: 284 GKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQY---ECTA--CPSGTYKPEGSPGGIS 338
Query: 173 FCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY--SGVNCELEIDECWS 230
C+P C P +N + C+C Y SG CEL C +
Sbjct: 339 SCIP------C----------PDENHTSPPGSTSPEDCVCREGYRASGQTCELV--HCPA 380
Query: 231 -QPCLNGATCQDALGAYF-----CDCAPGF 254
+P NG Q+ +F C PGF
Sbjct: 381 LKPPENGYFIQNTCNNHFNAACGVRCHPGF 410
Score = 33.5 bits (75), Expect = 1.5
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
C S PC ++G C++ Y+C C + + G +C E
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETE 1307
Score = 33.5 bits (75), Expect = 1.5
Identities = 13/32 (40%), Positives = 15/32 (46%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSC 56
S C N C SN C+N +TC D C C
Sbjct: 1378 SHCELNINECQSNPCRNQATCVDELNSYSCKC 1409
Score = 33.1 bits (74), Expect = 1.9
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)
Query: 660 SGSSLNVKAGCVRKDWCE-SQPCQSRGRCINLWLSYQCDCHRPY--EGPNC 707
+GS V C+ D C C C+N+ SY C C PY +G NC
Sbjct: 1733 NGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNC 1783
Score = 32.3 bits (72), Expect = 3.3
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 147 IDHDECA-SSPCQNGAVCQDGIDGYSCFCVPGYQG 180
+D DECA S C A C + Y C CVP Y G
Sbjct: 1744 LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 32.0 bits (71), Expect = 4.3
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 11/105 (10%)
Query: 1107 LSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCP 1166
L + E + + P E F S + G CN+ L G S C+
Sbjct: 1682 LPHCERISCGVPPPLENGFH--SADDFYAGSTVTYQCNNGYYLLGD------SRMFCTDN 1733
Query: 1167 LGWSGKHCE-LNIDECF--SNPCIHGNCSDRVAAYHCTCEPGYTG 1208
W+G L++DEC S+ H +C + +Y C+C P YTG
Sbjct: 1734 GSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 32.0 bits (71), Expect = 4.3
Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 8/94 (8%)
Query: 1200 CTCEPGYTGVNCE-VDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFT--GKFCRQSRLP 1255
CT + GV+ +D+D C C+ A+C++ Y C C +T GK C + +
Sbjct: 1730 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEP-IK 1788
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
GN + ++ G E+ C+ G+
Sbjct: 1789 CKAPGNPENG---HSSGEIYTVGAEVTFSCQEGY 1819
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 240 bits (612), Expect = 8e-63
Identities = 121/331 (36%), Positives = 166/331 (50%), Gaps = 8/331 (2%)
Query: 14 LSFSLLIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDP 73
++ L + +K S C + C C + SC+ + C+ D
Sbjct: 294 VALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY-DA 352
Query: 74 CFSNPCQGSATCVNTPGER---SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPI 130
C PCQ +A+C++ ++ +F C C PGY+G +C++ I C + C++G C
Sbjct: 353 CQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 412
Query: 131 YPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQ-DGIDGYSCFCVPGYQGRHCDLEVDE 189
C CP GY G CE D CASSPCQN C DG+ ++C C PG+ G C +D
Sbjct: 413 GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDF 471
Query: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
CA PC + TC + Y C+C Y G+ CE E +EC S PCLN ATC+D + Y C
Sbjct: 472 CALSPCAH-GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECV 530
Query: 250 CAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP 309
C + G HCEL D CA+ CL+G C +C C GFTG C+ + C S P
Sbjct: 531 CLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCIC-APGFTGEECDIDINECDSNP 589
Query: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEIDL 340
CH+ +C D + Y CHC G+ GA CEI L
Sbjct: 590 CHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Score = 217 bits (552), Expect = 7e-56
Identities = 113/322 (35%), Positives = 147/322 (45%), Gaps = 68/322 (21%)
Query: 119 CQHGGICHQDPIYPV--CICPAGYAGRFCEIDHDECASSPCQNGAVC------QDGIDGY 170
C G C P C C Y G FCE ++D C PCQN A C QDG +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDG-SNF 376
Query: 171 SCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWS 230
+C C+PGY G C ++D C DPC+N ATC++ + +TC CP Y G CE ++D C S
Sbjct: 377 TCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCAS 436
Query: 231 QPCLNGATCQDALGAYFCDCAPGFLGD--------------------------------- 257
PC N TC + C+C+PGF G
Sbjct: 437 SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPG 496
Query: 258 ----HCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNN 313
+CE +EC S PCL+ C D N Y C C + GTHCE C + C N
Sbjct: 497 YHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAE-YKGTHCELYKDPCANVSCLNG 555
Query: 314 ATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSF 373
ATC+ N TC C PG+TG +C+ID+NEC+SNPC G C++
Sbjct: 556 ATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLD----------------- 598
Query: 374 SYHEASGYVCICQPGFTGIHCE 395
+ +GY C C G+ G +CE
Sbjct: 599 ---QPNGYNCHCPHGWVGANCE 617
Score = 214 bits (546), Expect = 4e-55
Identities = 113/319 (35%), Positives = 158/319 (49%), Gaps = 40/319 (12%)
Query: 170 YSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN-----EIGRYTCICPHNYSGVNCELE 224
+SC C Y G C+ E D C PC+N A+C++ + +TC+C Y+G C+ +
Sbjct: 334 FSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 225 IDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLC-VDGENR 283
ID C PC NGATC +L + C C G+ G CE D CAS PC + G C VDG +
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVH- 451
Query: 284 YSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNEC 343
++CNC+ GFTG C L+ C PC + TC +Y C C PGY G CE + NEC
Sbjct: 452 FTCNCS-PGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSYKCLCDPGYHGLYCEEEYNEC 509
Query: 344 NSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSS 403
S PC + C +L +GY C+C + G HCE + C++
Sbjct: 510 LSAPCLNAATCRDL--------------------VNGYECVCLAEYKGTHCELYKDPCAN 549
Query: 404 NPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDG 463
C NG TC++ N TC C + G +C + C C + G+C+ D
Sbjct: 550 VSCLNGATCDSDGLNGTCICA------PGFTGEECDIDINECDSNPCHHGGSCL----DQ 599
Query: 464 QHGFSCLCPSGYTGSLCEI 482
+G++C CP G+ G+ CEI
Sbjct: 600 PNGYNCHCPHGWVGANCEI 618
Score = 177 bits (449), Expect = 6e-44
Identities = 89/258 (34%), Positives = 133/258 (51%), Gaps = 19/258 (7%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY 1198
+++ C S+PC + G C + C+C G++G C ID C +PC HG C +Y
Sbjct: 430 KVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSY 489
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C+PGY G+ CE + + C S C N ATC NGY C+C + G C + P
Sbjct: 490 KCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPC-- 547
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
N++C NG C C+C PGFTGE C+ DI+EC S+PC +GG C D N
Sbjct: 548 -----ANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNG 602
Query: 1319 FQCLCDVAFAGERCEVDL-------ADDLIS----DIFTTIGSVTVALLLILLLAIVASV 1367
+ C C + G CE+ L A+ L + ++ IG++ VA +L+L++ IV +
Sbjct: 603 YNCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLYIIIGALCVAFILMLIILIV-GI 661
Query: 1368 VTSNKRATQGTYSPSRQE 1385
++ QG+ P+ +E
Sbjct: 662 CRISRIEYQGSSRPAYEE 679
Score = 154 bits (389), Expect = 6e-37
Identities = 140/540 (25%), Positives = 218/540 (40%), Gaps = 98/540 (18%)
Query: 868 PTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDD------------FSCSCPA 915
P ++ NPV + C + PC NGGVC SR + +SC+CPA
Sbjct: 28 PRGSSLANPV---PAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPA 84
Query: 916 LTSGKACEEV-QWCGFSPCPHG---AQCQPVLQGFECIANAVFNGQSGQILFRSNGNITR 971
SG C+ V C +PC HG + G+ CI N + G + + S
Sbjct: 85 GISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS-----L 139
Query: 972 ELTNITFGFRTRDANVIILHAEKEPEFLNISIQDSRLF--FQLQSGNSFYMLSLTSLQSV 1029
T T R + A +EP+ + Q + +Q ++G + ++ +
Sbjct: 140 PATGWTESMAPRQLQPV--PATQEPDKILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVI 197
Query: 1030 NDGTWHEVTLSMTDPLSQTSRWQMEVDNETPFVTSTI----ATGSLNFLKDNTDI----- 1080
D ++ + S +S V E P TS AT SL L T
Sbjct: 198 PD-------IACGNASSNSSAGGRLVSFEVPQNTSVKIRQDATASLILLWKVTATGFQQC 250
Query: 1081 -YVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQ 1139
+ R++ ++ G + E+ + ++F GF+N + + + VV +
Sbjct: 251 SLIDGRSVTPLQASGGLVLLEEMLALGNNHFI---GFVNDSVTKSIVALRLTLVV----K 303
Query: 1140 LNVC-------NSNPCLHGGNC--EDIYSSYHCSCPLGWSGKHCELNIDECFSNPC---- 1186
++ C N C G C + +++ C+C + G CE D C PC
Sbjct: 304 VSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNA 362
Query: 1187 --IHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNF 1244
I N + + C C PGYTG C+ ID C C NGATCIS +G++C C +
Sbjct: 363 SCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGY 422
Query: 1245 TGKFCRQSRLP--STVCGNEKT------NLTC-----YNG-----------------GNC 1274
G C + P S+ C N T + TC + G G C
Sbjct: 423 FGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTC 482
Query: 1275 TEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
T KC+C PG+ G +CE++ +EC S PC+N C+DL+N ++C+C + G CE+
Sbjct: 483 RSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL 542
Score = 68.2 bits (165), Expect = 5e-11
Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 15/88 (17%)
Query: 112 GSCGKNSCQHGGIC----HQDPIYPV--------CICPAGYAGRFCEIDHDECASSPCQN 159
G C C++GG+C DP +P C CPAG +G C++ D CAS+PC +
Sbjct: 46 GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 160 G---AVCQDGIDGYSCFCVPGYQGRHCD 184
G + DGY C C GY+G +C+
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 67.8 bits (164), Expect = 7e-11
Identities = 46/140 (32%), Positives = 60/140 (42%), Gaps = 25/140 (17%)
Query: 347 PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPC 406
P +S+ +E S + G+ T PS ++ C C+ + G CEE + C PC
Sbjct: 309 PGESHANDLECSGK---GKCTTKPSEATFS------CTCEEQYVGTFCEE-YDACQRKPC 358
Query: 407 QNGGTC----ENLPG-NYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQ 461
QN +C E G N+TC C Y G C + C C N TCI
Sbjct: 359 QNNASCIDANEKQDGSNFTCVC------LPGYTGELCQSKIDYCILDPCRNGATCISSLS 412
Query: 462 DGQHGFSCLCPSGYTGSLCE 481
GF+C CP GY GS CE
Sbjct: 413 ----GFTCQCPEGYFGSACE 428
Score = 67.4 bits (163), Expect = 9e-11
Identities = 33/86 (38%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 152 CASSPCQNGAVCQD------------GIDGYSCFCVPGYQGRHCDLEVDECASDPCKN-- 197
CA+ PC+NG VC G GYSC C G G +C L D CAS+PC +
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 198 -EATCLNEIGRYTCICPHNYSGVNCE 222
++ + Y CIC Y G NCE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 64.3 bits (155), Expect = 8e-10
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 16/87 (18%)
Query: 266 CASQPCLHGGLCVD------------GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHN- 312
CA+QPC +GG+C GE YSC C +G +G +C+ + C S PCH+
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCP-AGISGANCQLVADPCASNPCHHG 106
Query: 313 --NATCEDSVDNYTCHCWPGYTGAQCE 337
+++ S D Y C C GY G CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 58.5 bits (140), Expect = 4e-08
Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 13/87 (14%)
Query: 73 PCFSNPCQGSATCVNTP----------GERSFLCKCPPGYSGTICETTIGSCGKNSCQHG 122
PC + PC+ C + P GE + C CP G SG C+ C N C HG
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 123 GICHQDPIYP---VCICPAGYAGRFCE 146
+CIC GY G CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 58.2 bits (139), Expect = 6e-08
Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 29/104 (27%)
Query: 305 CWSKPCHNNATCEDSVD------------NYTCHCWPGYTGAQCEIDLNECNSNPCQSNG 352
C ++PC N C + Y+C C G +GA C++ + C SNPC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCH-HG 106
Query: 353 ECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEE 396
C SS S + GY+CIC G+ G +CE+
Sbjct: 107 NC----------------SSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 58.2 bits (139), Expect = 6e-08
Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 17/87 (19%)
Query: 190 CASDPCKNEATCLN-------------EIGRYTCICPHNYSGVNCELEIDECWSQPCLNG 236
CA+ PC+N C + E G Y+C CP SG NC+L D C S PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPG-YSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 237 ---ATCQDALGAYFCDCAPGFLGDHCE 260
++ + Y C C G+ G +CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 57.8 bits (138), Expect = 7e-08
Identities = 20/41 (48%), Positives = 30/41 (73%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI 1178
+ +N C+SNPC HGG+C D + Y+C CP GW G +CE+++
Sbjct: 580 IDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Score = 55.8 bits (133), Expect = 3e-07
Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 16/91 (17%)
Query: 228 CWSQPCLNGATCQD------------ALGAYFCDCAPGFLGDHCELNTDECASQPCLHGG 275
C +QPC NG C Y C C G G +C+L D CAS PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 276 LCVDGENR---YSCNCTGSGFTGTHCETLMP 303
+ Y C C G+ G +CE +P
Sbjct: 108 CSSSSSSSSDGYLCIC-NEGYEGPNCEQALP 137
Score = 50.8 bits (120), Expect = 9e-06
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 19/95 (20%)
Query: 401 CSSNPCQNGGTCENLPG------------NYTCHCPFDNLSRTFYGGRDCSDILLGCTHQ 448
C++ PC+NGG C + P Y+C CP G +C + C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAG------ISGANCQLVADPCASN 101
Query: 449 QCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
C ++G C G+ C+C GY G CE A
Sbjct: 102 PC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQA 135
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 34 CLSNSCQNNSTCKDFSKDND----------CSCSDTANNLDKDCDNMKDPCFSNPC-QGS 82
C + C+N C + + SC+ A +C + DPC SNPC G+
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGS 113
+ ++ +LC C GY G CE + S
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 19/104 (18%)
Query: 343 CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNEC 401
C + PC++ G C + Q+ G P GY C C G +G +C+ + C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEP---------GYSCTCPAGISGANCQLVADPC 98
Query: 402 SSNPCQNG---GTCENLPGNYTCHCPFDNLSRTFYGGRDCSDIL 442
+SNPC +G + + Y C C Y G +C L
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCIC------NEGYEGPNCEQAL 136
Score = 44.7 bits (104), Expect = 6e-04
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
C + C NG C S + +C C +G+ C+ ++ C +PC HG C G+ C
Sbjct: 547 CANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCH 606
Query: 950 ANAVFNGQSGQI-LFRSNGNITRELTNI 976
+ G + +I L +G++ LTN+
Sbjct: 607 CPHGWVGANCEIHLQWKSGHMAESLTNM 634
Score = 43.9 bits (102), Expect = 0.001
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQW 927
N C SNPCH+GG C + + ++C CP G CE +QW
Sbjct: 583 NECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQW 622
Score = 38.1 bits (87), Expect = 0.060
Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 1/74 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQ-WCGFSPCPHGAQCQPVLQGFE 947
N C S PC N C + + C C A G CE + C C +GA C
Sbjct: 507 NECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGT 566
Query: 948 CIANAVFNGQSGQI 961
CI F G+ I
Sbjct: 567 CICAPGFTGEECDI 580
Score = 37.7 bits (86), Expect = 0.078
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 637 PSFVGCLQDIKIDW-------NHITLENISSGSSLNVKAG-----CVRK-DWCESQPCQS 683
P + G L KID+ N T + SG + G C K D C S PCQ+
Sbjct: 382 PGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQN 441
Query: 684 RGRCINLWLSYQCDCHRPYEGPNC 707
G C + + C+C + GP C
Sbjct: 442 NGTCYVDGVHFTCNCSPGFTGPTC 465
Score = 33.5 bits (75), Expect = 1.5
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREY 711
D+C PC + G C ++ SY+C C Y G C EY
Sbjct: 470 DFCALSPC-AHGTCRSVGTSYKCLCDPGYHGLYCEEEY 506
Score = 32.7 bits (73), Expect = 2.5
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 674 DWCESQPCQSRGRCINLWLS----YQCDCHRPYEGPNC 707
D C S PC G C + S Y C C+ YEGPNC
Sbjct: 96 DPCASNPCH-HGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 31.2 bits (69), Expect = 7.3
Identities = 12/32 (37%), Positives = 17/32 (53%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC + C +L Y+C C Y+G +C
Sbjct: 509 CLSAPCLNAATCRDLVNGYECVCLAEYKGTHC 540
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 236 bits (603), Expect = 9e-62
Identities = 113/272 (41%), Positives = 141/272 (51%), Gaps = 10/272 (3%)
Query: 85 CVNTPG------ERSFLCKCPPGYSGTICETTIGSCGKNS-CQHGGIC-HQDPIYPVCIC 136
C+ PG ++ + C C G+ G C + C + C++G C + C C
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 137 PAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
GY G CE+ DEC SPC+NG C D + YSC C PG+ G+ C+L CA PC
Sbjct: 317 RPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCF 376
Query: 197 NEATCLNE-IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
N C + G Y+C CP YSG NCE +ID C S PC NGA C D AY C C GF
Sbjct: 377 NGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS 436
Query: 256 GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT 315
G HC+ N D+CAS PC +GG C DG N +SC C G+TG +C + C PCHN AT
Sbjct: 437 GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCP-PGYTGRNCSAPVSRCEHAPCHNGAT 495
Query: 316 CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP 347
C + Y C C GY G C+ L E P
Sbjct: 496 CHERGHRYVCECARGYGGPNCQFLLPELPPGP 527
Score = 232 bits (592), Expect = 2e-60
Identities = 133/381 (34%), Positives = 180/381 (47%), Gaps = 64/381 (16%)
Query: 135 ICPAGYAGRFCEIDHDECASSPC--QNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
+C G+ G +C + C Q+G + G C C G+QGR+CD EC
Sbjct: 211 VCNPGWKGPYCT---EPICLPGCDEQHGFCDKPG----ECKCRVGWQGRYCD----ECIR 259
Query: 193 DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWS-QPCLNGATCQDA-LGAYFCDC 250
P TC + C C + G+ C +++ C +PC NGATC + G+Y C C
Sbjct: 260 YPGCLHGTCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSC 316
Query: 251 APGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPC 310
PG+ G CEL DEC PC +GG C D EN YSC C GF G CE C PC
Sbjct: 317 RPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCP-PGFYGKICELSAMTCADGPC 375
Query: 311 HNNATCEDSVDN-YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGL 369
N C DS D Y+C C GY+G CE ++ C+S+PC + +CV+L
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGD---------- 425
Query: 370 PSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLS 429
Y+C CQ GF+G HC+++V++C+S+PC NGGTC + +++C CP
Sbjct: 426 ----------AYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCP----- 470
Query: 430 RTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE-------- 481
Y GR+CS + C H C N TC + H + C C GY G C+
Sbjct: 471 -PGYTGRNCSAPVSRCEHAPCHNGATC----HERGHRYVCECARGYGGPNCQFLLPELPP 525
Query: 482 ----IATTLSFEGDG--FLWV 496
+ T EG G F WV
Sbjct: 526 GPAVVDLTEKLEGQGGPFPWV 546
Score = 225 bits (573), Expect = 3e-58
Identities = 118/320 (36%), Positives = 153/320 (47%), Gaps = 35/320 (10%)
Query: 89 PGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEID 148
PGE CKC G+ G C+ I G C HG C Q C C G+ G FC D
Sbjct: 240 PGE----CKCRVGWQGRYCDECIRYPG---CLHG-TCQQPW---QCNCQEGWGGLFCNQD 288
Query: 149 HDECAS-SPCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIG 206
+ C PC+NGA C + G Y+C C PGY G C+L +DEC PCKN +C +
Sbjct: 289 LNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLEN 348
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDAL-GAYFCDCAPGFLGDHCELNTDE 265
Y+C CP + G CEL C PC NG C D+ G Y C C G+ G +CE D
Sbjct: 349 SYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDY 408
Query: 266 CASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTC 325
C+S PC +G CVD + Y C C +GF+G HC+ + C S PC N TC D V++++C
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQ-AGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSC 467
Query: 326 HCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCIC 385
C PGYTG C ++ C PC + C + YVC C
Sbjct: 468 TCPPGYTGRNCSAPVSRCEHAPCHNGATC--------------------HERGHRYVCEC 507
Query: 386 QPGFTGIHCEEDVNECSSNP 405
G+ G +C+ + E P
Sbjct: 508 ARGYGGPNCQFLLPELPPGP 527
Score = 214 bits (545), Expect = 5e-55
Identities = 101/271 (37%), Positives = 138/271 (50%), Gaps = 13/271 (4%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
CL +CQ C C+ N C + K PC+ ATC NT G+ S
Sbjct: 263 CLHGTCQQPWQCNCQEGWGGLFCNQDLNY----CTHHK------PCKNGATCTNT-GQGS 311
Query: 94 FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECA 153
+ C C PGY+G CE I C + C++GG C C CP G+ G+ CE+ CA
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCA 371
Query: 154 SSPCQNGAVCQDGIDG-YSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCIC 212
PC NG C D DG YSC C GY G +C+ ++D C+S PC N A C++ Y C C
Sbjct: 372 DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRC 431
Query: 213 PHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCL 272
+SG +C+ +D+C S PC NG TC+D + + C C PG+ G +C C PC
Sbjct: 432 QAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 273 HGGLCVDGENRYSCNCTGSGFTGTHCETLMP 303
+G C + +RY C C G+ G +C+ L+P
Sbjct: 492 NGATCHERGHRYVCEC-ARGYGGPNCQFLLP 521
Score = 202 bits (514), Expect = 2e-51
Identities = 96/249 (38%), Positives = 131/249 (52%), Gaps = 5/249 (2%)
Query: 26 FCNKNNTRCLSNS-CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
FCN++ C + C+N +TC + + + +CS C+ D C +PC+ +
Sbjct: 284 FCNQDLNYCTHHKPCKNGATCTNTGQGS-YTCSCRPGYTGATCELGIDECDPSPCKNGGS 342
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV-CICPAGYAGR 143
C + E S+ C CPPG+ G ICE + +C C +GG C P C CP GY+G
Sbjct: 343 CTDL--ENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGF 400
Query: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
CE D C+SSPC NGA C D D Y C C G+ GRHCD VD+CAS PC N TC +
Sbjct: 401 NCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRD 460
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 263
+ ++C CP Y+G NC + C PC NGATC + Y C+CA G+ G +C+
Sbjct: 461 GVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLL 520
Query: 264 DECASQPCL 272
E P +
Sbjct: 521 PELPPGPAV 529
Score = 164 bits (414), Expect = 7e-40
Identities = 83/250 (33%), Positives = 121/250 (48%), Gaps = 27/250 (10%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRV- 1195
L ++ C+ +PC +GG+C D+ +SY C+CP G+ GK CEL+ C PC +G CSD
Sbjct: 327 LGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPD 386
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Y C C GY+G NCE ID C S C+NGA C+ + Y C C F+G+ C +
Sbjct: 387 GGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNV-- 444
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
++ + C NGG C + + C C PG+TG C + C PC NG C +
Sbjct: 445 -----DDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHER 499
Query: 1316 LNKFQCLCDVAFAGERCE------------VDLADDLISD------IFTTIGSVTVALLL 1357
+++ C C + G C+ VDL + L + G + V +LL
Sbjct: 500 GHRYVCECARGYGGPNCQFLLPELPPGPAVVDLTEKLEGQGGPFPWVAVCAGVILVLMLL 559
Query: 1358 ILLLAIVASV 1367
+ A+V V
Sbjct: 560 LGCAAVVVCV 569
Score = 156 bits (394), Expect = 2e-37
Identities = 76/202 (37%), Positives = 104/202 (51%), Gaps = 11/202 (5%)
Query: 1140 LNVCNSN-PCLHGGNCEDI-YSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
LN C + PC +G C + SY CSC G++G CEL IDEC +PC +G +C+D
Sbjct: 289 LNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLEN 348
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI-SHTNGYSCLCFGNFTGKFCRQSRLP 1255
+Y CTC PG+ G CE+ C C NG C S GYSC C ++G C +
Sbjct: 349 SYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKK--- 405
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
C + C NG C + C C+ GF+G C+ ++D+CAS PC NGG C+D
Sbjct: 406 IDYCSSSP----CSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDG 461
Query: 1316 LNKFQCLCDVAFAGERCEVDLA 1337
+N F C C + G C ++
Sbjct: 462 VNDFSCTCPPGYTGRNCSAPVS 483
Score = 131 bits (329), Expect = 5e-30
Identities = 70/199 (35%), Positives = 96/199 (48%), Gaps = 24/199 (12%)
Query: 1143 CNSNPCLHGGNCEDIYSSY----HCSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAA 1197
C CL G C++ + C C +GW G++C DEC P C+HG C
Sbjct: 221 CTEPICLPG--CDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGCLHGTCQQ---P 271
Query: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQ-CANGATCISHTNG-YSCLCFGNFTGKFCRQSRLP 1255
+ C C+ G+ G+ C D++ C H+ C NGATC + G Y+C C +TG C
Sbjct: 272 WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGI-- 329
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
+E C NGG+CT+ + C C PGF G+ CE CA PC NGG C D
Sbjct: 330 -----DECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDS 384
Query: 1316 LN-KFQCLCDVAFAGERCE 1333
+ + C C V ++G CE
Sbjct: 385 PDGGYSCRCPVGYSGFNCE 403
Score = 114 bits (285), Expect = 7e-25
Identities = 56/174 (32%), Positives = 74/174 (42%), Gaps = 3/174 (1%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C C N C D S D SC +C+ D C S+PC A CV
Sbjct: 363 CELSAMTCADGPCFNGGRCSD-SPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
+ ++LC+C G+SG C+ + C + C +GG C C CP GY GR C
Sbjct: 422 DLGD--AYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCS 479
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEAT 200
C +PC NGA C + Y C C GY G +C + E P + T
Sbjct: 480 APVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVDLT 533
Score = 57.0 bits (136), Expect = 1e-07
Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C S+PC NGG C +DFSC+CP +G+ C V C +PC +GA C +
Sbjct: 445 DDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYV 504
Query: 948 CIANAVFNGQSGQIL 962
C + G + Q L
Sbjct: 505 CECARGYGGPNCQFL 519
Score = 56.6 bits (135), Expect = 2e-07
Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 890 SCKSNPCHNGGVCHSRWDD-FSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
+C PC NGG C D +SC CP SG CE+ + +C SPC +GA+C + +
Sbjct: 369 TCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYL 428
Query: 948 CIANAVFNGQ 957
C A F+G+
Sbjct: 429 CRCQAGFSGR 438
Score = 53.9 bits (128), Expect = 1e-06
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECI 949
C S+PC NG C D + C C A SG+ C++ V C SPC +G C+ + F C
Sbjct: 409 CSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCT 468
Query: 950 ANAVFNGQS 958
+ G++
Sbjct: 469 CPPGYTGRN 477
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 887 GDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ- 944
G + C +PC NGG C + +SC+CP GK CE C PC +G +C
Sbjct: 328 GIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDG 387
Query: 945 GFECIANAVFNG 956
G+ C ++G
Sbjct: 388 GYSCRCPVGYSG 399
Score = 41.2 bits (95), Expect = 0.007
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 895 PCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANA 952
PC NG C ++ ++CSC +G CE + C SPC +G C + + C
Sbjct: 297 PCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPP 356
Query: 953 VFNGQ 957
F G+
Sbjct: 357 GFYGK 361
Score = 38.1 bits (87), Expect = 0.060
Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 670 CVRK-DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C +K D+C S PC + +C++L +Y C C + G +C
Sbjct: 402 CEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHC 440
Score = 36.6 bits (83), Expect = 0.17
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
CE PC + C Y C+C R Y GPNC
Sbjct: 485 CEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Score = 33.5 bits (75), Expect = 1.5
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C+ PC++ G C +L SY C C + G C
Sbjct: 330 DECDPSPCKNGGSCTDLENSYSCTCPPGFYGKIC 363
Score = 31.2 bits (69), Expect = 7.3
Identities = 13/34 (38%), Positives = 16/34 (47%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
D C S PC + G C + + C C Y G NC
Sbjct: 445 DDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNC 478
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 232 bits (591), Expect = 2e-60
Identities = 119/312 (38%), Positives = 158/312 (50%), Gaps = 23/312 (7%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
CLS + N C SK +C C + + C + TC +TP +
Sbjct: 222 CLSGCHEQNGYC---SKPAECLCRPGWQG------RLCNECIPHNGCRHGTC-STPWQ-- 269
Query: 94 FLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
C C G+ G C+ + C +S C++G C C C GY G CE++ E
Sbjct: 270 --CTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE 327
Query: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCL--NEIGRYT 209
C S+PC+NG C+D DGY C C PGY G HC+ CA PC N +C N+ Y
Sbjct: 328 CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYA 387
Query: 210 CICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ 269
C CP N++G NCE ++D C S PC NG C + + C C PGF G +CEL+ +CA
Sbjct: 388 CECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARN 447
Query: 270 PCLHGGLCVDGENRYSCNCTGSGFTGTHCE--TLMPLCWSKPCHNNATC--EDSVDNYTC 325
PC HGG C D EN C C +GF+G CE T + C S PC N ATC + S D + C
Sbjct: 448 PCAHGGTCHDLENGLMCTCP-AGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVC 506
Query: 326 HCWPGYTGAQCE 337
+C G+ G++CE
Sbjct: 507 NCPYGFVGSRCE 518
Score = 224 bits (570), Expect = 6e-58
Identities = 132/411 (32%), Positives = 177/411 (43%), Gaps = 57/411 (13%)
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGG-ICHQDPIYPVCICPAGYAGRFCEIDHDE 151
S+ C Y G C C K + G +C D C G+ G +C+
Sbjct: 170 SYRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDGNLS---CLPGWTGEYCQ--QPI 221
Query: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCI 211
C S + C + C C PG+QGR C+ EC TC + C
Sbjct: 222 CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCN----ECIPHNGCRHGTCSTP---WQCT 271
Query: 212 CPHNYSGVNCELEIDECWSQ-PCLNGATCQDA-LGAYFCDCAPGFLGDHCELNTDECASQ 269
C + G+ C+ +++ C PC NGATC ++ +Y C C PG+ G CEL EC S
Sbjct: 272 CDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSN 331
Query: 270 PCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVD--NYTCHC 327
PC +GG C D E+ Y C C G+ G HCE C PC N +C + NY C C
Sbjct: 332 PCRNGGSCKDQEDGYHCLCP-PGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACEC 390
Query: 328 WPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQP 387
P +TG+ CE ++ C SNPC + G+C+ + +C C+P
Sbjct: 391 PPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR--------------------MCRCRP 430
Query: 388 GFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS--DILLGC 445
GFTG +CE V++C+ NPC +GGTC +L C CP + GR C + C
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAG------FSGRRCEVRTSIDAC 484
Query: 446 THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWV 496
C N TC F C CP G+ GS CE L F WV
Sbjct: 485 ASSPCFNRATCYTDLSTDT--FVCNCPYGFVGSRCEFPVGLP---PSFPWV 530
Score = 174 bits (441), Expect = 5e-43
Identities = 84/205 (40%), Positives = 110/205 (53%), Gaps = 12/205 (5%)
Query: 1140 LNVC-NSNPCLHGGNCEDI-YSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
LN C + +PC +G C + SY C+C G++G CEL + EC SNPC +G +C D+
Sbjct: 285 LNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQED 344
Query: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG--YSCLCFGNFTGKFCRQSRL 1254
YHC C PGY G++CE +C C NG +C G Y+C C NFTG C +
Sbjct: 345 GYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKV- 403
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
+ T+ C NGG C C CRPGFTG +CE + +CA +PC +GG C D
Sbjct: 404 ------DRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHD 457
Query: 1315 LLNKFQCLCDVAFAGERCEVDLADD 1339
L N C C F+G RCEV + D
Sbjct: 458 LENGLMCTCPAGFSGRRCEVRTSID 482
Score = 171 bits (432), Expect = 6e-42
Identities = 89/243 (36%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Query: 26 FCNKNNTRCLSNS-CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
FC+++ C +S C+N +TC + S +C+ DC+ C SNPC+ +
Sbjct: 280 FCDQDLNYCTHHSPCKNGATCSN-SGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGS 338
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGIC---HQDPIYPVCICPAGYA 141
C + E + C CPPGY G CE + SC + C +GG C +Q Y C CP +
Sbjct: 339 CKDQ--EDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANY-ACECPPNFT 395
Query: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
G CE D C S+PC NG C + C C PG+ G +C+L V +CA +PC + TC
Sbjct: 396 GSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTC 455
Query: 202 LNEIGRYTCICPHNYSGVNCEL--EIDECWSQPCLNGATCQDALG--AYFCDCAPGFLGD 257
+ C CP +SG CE+ ID C S PC N ATC L + C+C GF+G
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Query: 258 HCE 260
CE
Sbjct: 516 RCE 518
Score = 170 bits (431), Expect = 8e-42
Identities = 98/267 (36%), Positives = 133/267 (49%), Gaps = 26/267 (9%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDR-- 1194
L+L+ C+SNPC +GG+C+D YHC CP G+ G HCE + C +PC + G+C +R
Sbjct: 323 LELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQ 382
Query: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRL 1254
A Y C C P +TG NCE +D C S+ CANG C++ C C FTG +C L
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYC---EL 439
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE--KDIDECASDPCVNGGLC 1312
+ C C +GG C + + L C C GF+G CE ID CAS PC N C
Sbjct: 440 HVSDCARN----PCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATC 495
Query: 1313 QDLL--NKFQCLCDVAFAGERCEVDLADDLISDIFTTIG-SVTVALLLILLLAIVASVVT 1369
L + F C C F G RCE + + F + S+ V L ++L+L + +V
Sbjct: 496 YTDLSTDTFVCNCPYGFVGSRCEFPVG---LPPSFPWVAVSLGVGLAVLLVLLGMVAVAV 552
Query: 1370 SNKRATQGTYSPSRQEKEGSRVEMWNL 1396
R R+ +GSR M NL
Sbjct: 553 RQLRL--------RRPDDGSREAMNNL 571
Score = 130 bits (327), Expect = 9e-30
Identities = 59/165 (35%), Positives = 85/165 (51%), Gaps = 6/165 (3%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C + C N +C++ ++ + +C N +C+ D C SNPC C+
Sbjct: 359 CEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCL 418
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
N R +C+C PG++GT CE + C +N C HGG CH +C CPAG++GR CE
Sbjct: 419 NRGPSR--MCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCE 476
Query: 147 I--DHDECASSPCQNGAVCQDGI--DGYSCFCVPGYQGRHCDLEV 187
+ D CASSPC N A C + D + C C G+ G C+ V
Sbjct: 477 VRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPV 521
Score = 73.9 bits (180), Expect = 1e-12
Identities = 42/126 (33%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
S C K RC SN C N C + C C C+ C NPC T
Sbjct: 397 SNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTG--TYCELHVSDCARNPCAHGGT 454
Query: 85 CVNTPGERSFLCKCPPGYSGTICE--TTIGSCGKNSCQHGGICHQDPIYP--VCICPAGY 140
C + E +C CP G+SG CE T+I +C + C + C+ D VC CP G+
Sbjct: 455 CHDL--ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGF 512
Query: 141 AGRFCE 146
G CE
Sbjct: 513 VGSRCE 518
Score = 59.3 bits (142), Expect = 3e-08
Identities = 26/88 (29%), Positives = 40/88 (45%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
++C + + C N C + TC D C+C + + D C S+PC AT
Sbjct: 435 TYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRAT 494
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIG 112
C +F+C CP G+ G+ CE +G
Sbjct: 495 CYTDLSTDTFVCNCPYGFVGSRCEFPVG 522
Score = 56.2 bits (134), Expect = 2e-07
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
C SNPC NGG C +R C C +G CE V C +PC HG C + G C
Sbjct: 406 CTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCT 465
Query: 950 ANAVFNGQSGQI 961
A F+G+ ++
Sbjct: 466 CPAGFSGRRCEV 477
Score = 51.6 bits (122), Expect = 5e-06
Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQG-- 945
+ C SNPC NGG C + D + C CP G CE C SPC +G C+ QG
Sbjct: 326 SECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385
Query: 946 FECIANAVFNGQS 958
+ C F G +
Sbjct: 386 YACECPPNFTGSN 398
Score = 51.6 bits (122), Expect = 5e-06
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE---EVQWCGFSPCPHGAQCQPVLQG 945
+ C NPC +GG CH + C+CPA SG+ CE + C SPC + A C L
Sbjct: 442 SDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501
Query: 946 FECIANAVF 954
+ N +
Sbjct: 502 DTFVCNCPY 510
Score = 49.3 bits (116), Expect = 3e-05
Identities = 22/53 (41%), Positives = 30/53 (56%), Gaps = 3/53 (5%)
Query: 890 SCKSNPCHNGGVCHSRWD--DFSCSCPALTSGKACEE-VQWCGFSPCPHGAQC 939
SC +PC NGG C R +++C CP +G CE+ V C +PC +G QC
Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQC 417
Score = 42.7 bits (99), Expect = 0.002
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 894 NPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIAN 951
+PC NG C +S ++C+C +G CE E+ C +PC +G C+ G+ C+
Sbjct: 292 SPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCP 351
Query: 952 AVFNG 956
+ G
Sbjct: 352 PGYYG 356
Score = 38.9 bits (89), Expect = 0.035
Identities = 32/130 (24%), Positives = 46/130 (35%), Gaps = 44/130 (33%)
Query: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL---TCYNGGNCTEFQTELKCMCRPGFTGE 1292
Y +C N+ G C S +C + C GN + C PG+TGE
Sbjct: 171 YRVICSDNYYGDNC------SRLCKKRNDHFGHYVCQPDGNLS---------CLPGWTGE 215
Query: 1293 WCEKDI---------------DECASDPCVNGGLCQDLL-----------NKFQCLCDVA 1326
+C++ I EC P G LC + + +QC CD
Sbjct: 216 YCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEG 275
Query: 1327 FAGERCEVDL 1336
+ G C+ DL
Sbjct: 276 WGGLFCDQDL 285
Score = 34.3 bits (77), Expect = 0.87
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 668 AGCVRK-DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ C +K D C S PC + G+C+N S C C + G C
Sbjct: 397 SNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYC 437
Score = 33.1 bits (74), Expect = 1.9
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 889 NSCKSNPCHNGGVCHS--RWDDFSCSCPALTSGKACE 923
++C S+PC N C++ D F C+CP G CE
Sbjct: 482 DACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 214 bits (545), Expect = 5e-55
Identities = 152/539 (28%), Positives = 237/539 (43%), Gaps = 67/539 (12%)
Query: 187 VDECAS-DPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC-QDALG 244
+ C+S +P + R+ C P + +N + + C S PC N TC QD +
Sbjct: 881 IARCSSPEPMADRLLLTTPTHRFQCKGPVD---INIVAKCNACLSSPCKNNGTCTQDPVE 937
Query: 245 AYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENR---YSCNCTGSGFTGTHCETL 301
Y C C + G C + + C PC HGG C ++ +SC+C GF G CE
Sbjct: 938 LYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCP-LGFEGQRCEIN 996
Query: 302 MPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNEC--NSNPCQSNGECVELSS 359
C C NNATC D ++NY C C P YTG C+ ++ C N CQ +C+ L
Sbjct: 997 PDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLD- 1055
Query: 360 EKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNY 419
G+ C C PG++G CE D ++C ++ C++G C + Y
Sbjct: 1056 -------------------KGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGY 1096
Query: 420 TCHCPFDNLSRTFYGGRDCSD----ILL---GCTHQQCLNNGTCIPHFQDGQHGFSCLCP 472
TC CP + G C +LL C +C N CI Q+ +C CP
Sbjct: 1097 TCTCP------QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEP----TCRCP 1146
Query: 473 SGYTGSLCEIATTLSFEG-DGFLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDV 531
G+ G CE T++F G D ++ + S V + NI+L+ T + +LL++ + D
Sbjct: 1147 PGFAGPRCEKLITVNFVGKDSYVELASAKVRPQ---ANISLQVATDKDNGILLYKGDNDP 1203
Query: 532 FVKLELLSGYIHLSIQVNNQSKVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKC 591
+ LEL G++ L + ++ +DG++H VE++ TL L+ D K
Sbjct: 1204 -LALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQ-TLNLVVDKGTPKS 1261
Query: 592 IAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWN 651
+ K L+ ++ +LGG+P TS G++ L F GC+ +++I+ N
Sbjct: 1262 LGK----LQKQPAVGINSPLYLGGIP---TSTGLSALRQGTDRPLGGFHGCIHEVRIN-N 1313
Query: 652 HITLENISSGSSLNVKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
+ SL V GC C+ C+S + S C+C + GP C +E
Sbjct: 1314 ELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKD-----SVVCECRPGWTGPLCDQE 1367
Score = 192 bits (489), Expect = 1e-48
Identities = 117/364 (32%), Positives = 170/364 (46%), Gaps = 36/364 (9%)
Query: 5 NINYLLIFYLSFSLLIYIK-NSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTA--- 60
N+++L LS++ L I ++F + R L+ + S+ + S ++ S S A
Sbjct: 797 NMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGT 856
Query: 61 NNLDKDCD----------NMKDP----CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTI 106
N L DC K+P C S + TP R F CK P +
Sbjct: 857 NPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHR-FQCKGPVDIN--- 912
Query: 107 CETTIGSCGKNSCQHGGICHQDPIYPV-CICPAGYAGRFCEIDHDECASSPCQNGAVCQ- 164
+C + C++ G C QDP+ C CP Y G+ C + + C +PCQ+G C
Sbjct: 913 IVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL 972
Query: 165 --DGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222
DG+SC C G++G+ C++ D+C + C+N ATC++ I Y CICP NY+G C+
Sbjct: 973 SDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCD 1032
Query: 223 LEIDECWSQ--PCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDG 280
ID C + C + A C + C+C PG+ G CE + D+C + C HG CVD
Sbjct: 1033 EVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDT 1092
Query: 281 ENRYSCNCTGSGFTGTHCETLMPL-------CWSKPCHNNATCEDSVDNYTCHCWPGYTG 333
N Y+C C GF+G CE P+ C C N A C TC C PG+ G
Sbjct: 1093 INGYTCTCP-QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAG 1151
Query: 334 AQCE 337
+CE
Sbjct: 1152 PRCE 1155
Score = 152 bits (383), Expect = 3e-36
Identities = 71/207 (34%), Positives = 105/207 (50%), Gaps = 13/207 (6%)
Query: 1132 SVVTGCLQLNVCNSNPCLHGGNC-EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN 1190
++V C N C S+PC + G C +D Y C+CP + GK C + I+ C NPC HG
Sbjct: 912 NIVAKC---NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGG 968
Query: 1191 C----SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTG 1246
+ C+C G+ G CE++ D+C+ + C N ATC+ N Y C+C N+TG
Sbjct: 969 TCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTG 1028
Query: 1247 KFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPC 1306
+ C + + V + NL C + C C C PG++G+ CE D D+C + C
Sbjct: 1029 ELCDEV-IDHCV---PELNL-CQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKC 1083
Query: 1307 VNGGLCQDLLNKFQCLCDVAFAGERCE 1333
+G C D +N + C C F+G CE
Sbjct: 1084 RHGAQCVDTINGYTCTCPQGFSGPFCE 1110
Score = 135 bits (340), Expect = 3e-31
Identities = 72/207 (34%), Positives = 96/207 (46%), Gaps = 20/207 (9%)
Query: 1140 LNVCNSNPCLHGGNC---EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRV 1195
+N C NPC HGG C + + CSCPLG+ G+ CE+N D+C N C + C D +
Sbjct: 956 INTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGI 1015
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNC--QSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSR 1253
Y C C P YTG C+ ID+C + + C + A CI G+SC C ++GK C
Sbjct: 1016 NNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETD- 1074
Query: 1254 LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK-------DIDECASDPC 1306
+ C K C +G C + C C GF+G +CE C C
Sbjct: 1075 --NDDCVAHK----CRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYEC 1128
Query: 1307 VNGGLCQDLLNKFQCLCDVAFAGERCE 1333
NG C + + C C FAG RCE
Sbjct: 1129 QNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
Score = 107 bits (267), Expect = 8e-23
Identities = 105/406 (25%), Positives = 159/406 (39%), Gaps = 70/406 (17%)
Query: 885 CAGDNS-CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--------EVQWCGFSPCPH 935
C DN C ++ C +G C + ++C+CP SG CE + C C +
Sbjct: 1071 CETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQN 1130
Query: 936 GAQCQPVLQGFECIANAVFNGQSGQILFRSN-----------GNITRELTNITFGFRT-R 983
GAQC V Q C F G + L N R NI+ T +
Sbjct: 1131 GAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDK 1190
Query: 984 DANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEV---TLS 1040
D +++ + +P L + RL + S ++ S+++VNDG +H V TL+
Sbjct: 1191 DNGILLYKGDNDPLALELYQGHVRLVYDSLSSPP---TTVYSVETVNDGQFHSVELVTLN 1247
Query: 1041 MT-----DPLSQTSRWQME----VDNETPFVTSTIATGS-LNFLKDNTDIYVGDRAIDNI 1090
T D + S +++ V +P I T + L+ L+ TD +G
Sbjct: 1248 QTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLG------- 1300
Query: 1091 KGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLH 1150
G GC+ + I N+ Q+ + L + V GC VC
Sbjct: 1301 -GFHGCIHEVRIN--------------NELQDFKALPPQSLGVSPGCKSCTVCKH----- 1340
Query: 1151 GGNCEDIYS-SYHCSCPLGWSGKHCELNI-DECFSNPCIHGNCSDRVAAYHCTCEPGYTG 1208
G C + S C C GW+G C+ D C + C HG C +Y C C GY G
Sbjct: 1341 -GLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGG 1399
Query: 1209 VNCEVDIDN---CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
C+ D+ C + +C +G IS CLC F+G+ C+Q
Sbjct: 1400 DLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1445
Score = 97.8 bits (242), Expect = 6e-20
Identities = 56/165 (33%), Positives = 78/165 (47%), Gaps = 14/165 (8%)
Query: 1181 CFSNPCIH-GNCS-DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI---SHTNG 1235
C S+PC + G C+ D V Y C C Y G +C V I+ C + C +G TC SH +G
Sbjct: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
Query: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
+SC C F G+ C + P N+ C N C + C+C P +TGE C+
Sbjct: 980 FSCSCPLGFEGQRCEIN--PDDCEDND-----CENNATCVDGINNYVCICPPNYTGELCD 1032
Query: 1296 KDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
+ ID C + C + C L F C C ++G+ CE D D
Sbjct: 1033 EVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDD 1077
Score = 77.4 bits (189), Expect = 9e-14
Identities = 50/181 (27%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 1162 HCSCPLGWSGK-----HCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDID 1216
HC C L W + + E I C S + + C+ G +N +
Sbjct: 860 HCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCK-GPVDINIVAKCN 918
Query: 1217 NCQSHQCANGATCISH-TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNC- 1274
C S C N TC Y C C ++ GK C TV N C +GG C
Sbjct: 919 ACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDC-------TVPINTCIQNPCQHGGTCH 971
Query: 1275 --TEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
+ C C GF G+ CE + D+C + C N C D +N + C+C + GE C
Sbjct: 972 LSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELC 1031
Query: 1333 E 1333
+
Sbjct: 1032 D 1032
Score = 71.2 bits (173), Expect = 6e-12
Identities = 81/357 (22%), Positives = 133/357 (37%), Gaps = 67/357 (18%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYGD 735
C+ CQ+ +CI + C C + GP C + G+D +
Sbjct: 1123 CDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDS----YVELASAKVRP 1178
Query: 736 TISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLVVKFV--LNDGNV 793
++S+ V T + +G+LL ++ + ++ RL + +SP V V +NDG
Sbjct: 1179 QANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQF 1238
Query: 794 HLISLKIKPYKIELYQSSQNLGFI-----SASTWKIEKGDVI------YIGGLPD----- 837
H +EL +Q L + S K++K + Y+GG+P
Sbjct: 1239 H---------SVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLS 1289
Query: 838 --KQETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNP------------------- 876
+Q T+ G F GCI +VR+NN+ +F P + ++P
Sbjct: 1290 ALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKD 1349
Query: 877 -VLVNVTQGCAGD-------NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC----EE 924
V+ G G + C + CH+ G C + + C C G C +
Sbjct: 1350 SVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATGTSYMCKCAEGYGGDLCDNKNDS 1408
Query: 925 VQWCGFSPCPHGAQCQPVLQGFE-CIANAVFNGQSGQILFRSNGNITRELTNITFGF 980
C C HG QC QG C+ F+G+ Q G + RE+ G+
Sbjct: 1409 ANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGY 1464
Score = 62.0 bits (149), Expect = 4e-09
Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 17/129 (13%)
Query: 154 SSPCQNGAVCQDGI------DGYSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLNEIG 206
S C++ VC+ G+ D C C PG+ G CD E D C C + C+
Sbjct: 1329 SPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGT 1387
Query: 207 RYTCICPHNYSGVNCELEIDE---CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 263
Y C C Y G C+ + D C + C +G G +C C PGF G+HC+
Sbjct: 1388 SYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ--- 1444
Query: 264 DECASQPCL 272
PCL
Sbjct: 1445 ---QENPCL 1450
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 34 CLSNSCQNNSTCKDFSKDN---DCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPG 90
C S + + C+ KD+ +C T D++ +DPC + C CV T
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEA---RDPCLGHRCH-HGKCVATG- 1386
Query: 91 ERSFLCKCPPGYSGTICET---TIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
S++CKC GY G +C+ + +C C HG D P C+C G++G C+
Sbjct: 1387 -TSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
Score = 59.3 bits (142), Expect = 3e-08
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 7/99 (7%)
Query: 93 SFLCKCPPGYSGTICETTIGS-CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE 151
S +C+C PG++G +C+ C + C HG Y +C C GY G C+ +D
Sbjct: 1350 SVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSY-MCKCAEGYGGDLCDNKNDS 1408
Query: 152 ---CASSPCQNGAVCQDGIDGYS-CFCVPGYQGRHCDLE 186
C++ C +G C G C C PG+ G HC E
Sbjct: 1409 ANACSAFKCHHGQ-CHISDQGEPYCLCQPGFSGEHCQQE 1446
Score = 55.1 bits (131), Expect = 5e-07
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 889 NSCKSNPCHNGGVCH---SRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ 944
N+C NPC +GG CH S D FSCSCP G+ CE C + C + A C +
Sbjct: 957 NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGIN 1016
Query: 945 GFECIANAVFNGQ 957
+ CI + G+
Sbjct: 1017 NYVCICPPNYTGE 1029
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 876 PVLVNVTQGCAGDNSCKSNPCHNGGVC-HSRWDDFSCSCPALTSGKACE-EVQWCGFSPC 933
PV +N+ C N+C S+PC N G C + + C+CP GK C + C +PC
Sbjct: 908 PVDINIVAKC---NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPC 964
Query: 934 PHGAQC---QPVLQGFECIANAVFNGQSGQI 961
HG C GF C F GQ +I
Sbjct: 965 QHGGTCHLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 18/123 (14%)
Query: 233 CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCL----HGGLCVDGENRYSCNC 288
C +G + C+C PG+ G C D+ A PCL H G CV Y C C
Sbjct: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLC----DQEARDPCLGHRCHHGKCVATGTSYMCKC 1393
Query: 289 TGSGFTGTHCET---LMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNS 345
G+ G C+ C + CH+ C C PG++G C+
Sbjct: 1394 -AEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ------QE 1446
Query: 346 NPC 348
NPC
Sbjct: 1447 NPC 1449
Score = 52.0 bits (123), Expect = 4e-06
Identities = 41/141 (29%), Positives = 58/141 (41%), Gaps = 34/141 (24%)
Query: 271 CLHGGLCVDGE-NRYSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATCEDSVDNYTCHCW 328
C HG LC E + C C G+TG C+ C CH+ C + +Y C C
Sbjct: 1338 CKHG-LCRSVEKDSVVCECR-PGWTGPLCDQEARDPCLGHRCHHGK-CVATGTSYMCKCA 1394
Query: 329 PGYTGAQCEI---DLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCIC 385
GY G C+ N C++ C +G+C + Y C+C
Sbjct: 1395 EGYGGDLCDNKNDSANACSAFKCH-HGQCHISDQGEPY-------------------CLC 1434
Query: 386 QPGFTGIHCEEDVNECSSNPC 406
QPGF+G HC+++ NPC
Sbjct: 1435 QPGFSGEHCQQE------NPC 1449
Score = 51.6 bits (122), Expect = 5e-06
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 13/101 (12%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDN-------MKDPCFSNPC 79
C +N C+++ C++ + C D C+C + C++ PC C
Sbjct: 1071 CETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSG--PFCEHPPPMVLLQTSPCDQYEC 1128
Query: 80 QGSATCVNTPGERSFLCKCPPGYSGTICE--TTIGSCGKNS 118
Q A C+ E + C+CPPG++G CE T+ GK+S
Sbjct: 1129 QNGAQCIVVQQEPT--CRCPPGFAGPRCEKLITVNFVGKDS 1167
Score = 49.3 bits (116), Expect = 3e-05
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 15/109 (13%)
Query: 377 EASGYVCICQPGFTGIHCEEDVNE-CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGG 435
E VC C+PG+TG C+++ + C + C + G C +Y C C YGG
Sbjct: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATGTSYMCKC------AEGYGG 1399
Query: 436 RDC---SDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
C +D C+ +C ++G C H D + CLC G++G C+
Sbjct: 1400 DLCDNKNDSANACSAFKC-HHGQC--HISDQGEPY-CLCQPGFSGEHCQ 1444
Score = 46.6 bits (109), Expect = 2e-04
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV-QWC--GFSPCPHGAQCQPVLQG 945
+ C+ N C N C +++ C CP +G+ C+EV C + C H A+C P+ +G
Sbjct: 998 DDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG 1057
Query: 946 FECIANAVFNGQ 957
F C ++G+
Sbjct: 1058 FSCECVPGYSGK 1069
Score = 40.0 bits (92), Expect = 0.016
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 1263 KTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCV----NGGLCQDLLNK 1318
K+ C +G + + + C CRPG+TG C+++ A DPC+ + G C
Sbjct: 1333 KSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQE----ARDPCLGHRCHHGKCVATGTS 1388
Query: 1319 FQCLCDVAFAGERCE 1333
+ C C + G+ C+
Sbjct: 1389 YMCKCAEGYGGDLCD 1403
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 210 bits (534), Expect = 9e-54
Identities = 146/516 (28%), Positives = 223/516 (43%), Gaps = 67/516 (12%)
Query: 207 RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ-DALGAYFCDCAPGFLGDHCELNTDE 265
++TC P + VN + + C S PC N TC D + Y C C GF G C++
Sbjct: 904 KFTCQGPVD---VNILAKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHA 960
Query: 266 CASQPCLHGGLC---VDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
C S PC HGG C E+ + C C GF G +CE + C C NN+TC D ++N
Sbjct: 961 CISNPCKHGGTCHLKEGEEDGFWCICA-DGFEGENCEVNVDDCEDNDCENNSTCVDGINN 1019
Query: 323 YTCHCWPGYTGAQCEIDLNEC--NSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
YTC C P YTG CE L+ C + NPCQ + +C+ G
Sbjct: 1020 YTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCI--------------------LTPKG 1059
Query: 381 YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS- 439
+ C C PG+ G HC+ D ++C N C+NG C + YTC CP Y G C
Sbjct: 1060 FKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICP------EGYSGLFCEF 1113
Query: 440 --DILL----GCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSF-EGDG 492
++L C + C N CI + C C GY G CE +++F +
Sbjct: 1114 SPPMVLPRTSPCDNFDCQNGAQCIVRINEP----ICQCLPGYQGEKCEKLVSVNFINKES 1169
Query: 493 FLWVKSGSVTTKGSVCNIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVNNQS 552
+L + S V + NI L+ T + +LL++ ++D + +EL G + S +
Sbjct: 1170 YLQIPSAKVRPQ---TNITLQIATDEDSGILLYKGDKD-HIAVELYRGRVRASYDTGSHP 1225
Query: 553 KVLLFISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNS- 611
++ +DG +H VE++ + +L+L D K I S QS F +
Sbjct: 1226 ASAIYSVETINDGNFHIVELLALDQ-SLSLSVDGGNPKIITNL-----SKQSTLNFDSPL 1279
Query: 612 FLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCV 671
++GG+P + VA L + SF GC++++ I+ + + + +
Sbjct: 1280 YVGGMP---GKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQTGILPGCEPC 1336
Query: 672 RKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
K C CQ + + C+C + GP C
Sbjct: 1337 HKKVCAHGTCQPSSQA-----GFTCECQEGWMGPLC 1367
Score = 197 bits (501), Expect = 6e-50
Identities = 133/463 (28%), Positives = 202/463 (43%), Gaps = 61/463 (13%)
Query: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICH----- 126
+PC SNPC+ TC + P + + C CP G+ G C+ I +C N C+HGG CH
Sbjct: 920 NPCLSNPCKNDGTCNSDPVD-FYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGE 978
Query: 127 QDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE 186
+D + CIC G+ G CE++ D+C + C+N + C DGI+ Y+C C P Y G C+ +
Sbjct: 979 EDGFW--CICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEK 1036
Query: 187 VDECASD--PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALG 244
+D CA D PC++++ C+ + C C Y G +C+++ D+C C NGA C DA+
Sbjct: 1037 LDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVN 1096
Query: 245 AYFCDCAPGFLGDHCELN-------TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTH 297
Y C C G+ G CE + T C + C +G C+ N C C G+ G
Sbjct: 1097 GYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCL-PGYQGEK 1155
Query: 298 CETL-------------MPLCWSKPCHN----NATCEDS--------VDNYTCHCWPGYT 332
CE L +P +P N AT EDS D+ + G
Sbjct: 1156 CEKLVSVNFINKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRV 1215
Query: 333 GAQCEIDLNECNS-----NPCQSNGECVELSSEKQYGRIT---GLPSSFSYHEASGYVCI 384
A + + ++ N VEL + Q ++ G P + +
Sbjct: 1216 RASYDTGSHPASAIYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNF 1275
Query: 385 CQPGFT-GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL 443
P + G+ + +V P QNG + N + + + + IL
Sbjct: 1276 DSPLYVGGMPGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQ----TGILP 1331
Query: 444 GC--THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIAT 484
GC H++ +GTC P Q GF+C C G+ G LC+ T
Sbjct: 1332 GCEPCHKKVCAHGTCQP---SSQAGFTCECQEGWMGPLCDQRT 1371
Score = 180 bits (456), Expect = 1e-44
Identities = 89/238 (37%), Positives = 114/238 (47%), Gaps = 13/238 (5%)
Query: 34 CLSNSCQNNSTCKDFSKD-NDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGER 92
CLSN C+N+ TC D C+C +DCD C SNPC+ TC GE
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKG--QDCDVPIHACISNPCKHGGTCHLKEGEE 979
Query: 93 S-FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE 151
F C C G+ G CE + C N C++ C C+CP Y G CE D
Sbjct: 980 DGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDF 1039
Query: 152 CAS--SPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
CA +PCQ+ + C G+ C C PGY G HCD++ D+C + CKN A C + + YT
Sbjct: 1040 CAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYT 1099
Query: 210 CICPHNYSGVNCEL-------EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
CICP YSG+ CE C + C NGA C + C C PG+ G+ CE
Sbjct: 1100 CICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 161 bits (408), Expect = 4e-39
Identities = 71/198 (35%), Positives = 101/198 (51%), Gaps = 10/198 (5%)
Query: 1141 NVCNSNPCLHGGNCE-DIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNC----SDRV 1195
N C SNPC + G C D Y C+CP G+ G+ C++ I C SNPC HG
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEE 979
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
+ C C G+ G NCEV++D+C+ + C N +TC+ N Y+CLC +TG+ C +
Sbjct: 980 DGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKL-- 1037
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
C + C + C KC C PG+ GE C+ D D+C + C NG C D
Sbjct: 1038 -DFCAQDLN--PCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDA 1094
Query: 1316 LNKFQCLCDVAFAGERCE 1333
+N + C+C ++G CE
Sbjct: 1095 VNGYTCICPEGYSGLFCE 1112
Score = 145 bits (365), Expect = 3e-34
Identities = 72/212 (33%), Positives = 102/212 (48%), Gaps = 16/212 (7%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDND---CSCSDTANNLDKDCDNMKDPCFSNPC 79
K C+ C+SN C++ TC + D C C+D ++C+ D C N C
Sbjct: 950 KGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEG--ENCEVNVDDCEDNDC 1007
Query: 80 QGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGK--NSCQHGGICHQDPIYPVCICP 137
+ ++TCV+ G ++ C CPP Y+G +CE + C + N CQH C P C C
Sbjct: 1008 ENNSTCVD--GINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKGFKCDCT 1065
Query: 138 AGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL-------EVDEC 190
GY G C+ID D+C + C+NGA C D ++GY+C C GY G C+ C
Sbjct: 1066 PGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPC 1125
Query: 191 ASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222
+ C+N A C+ I C C Y G CE
Sbjct: 1126 DNFDCQNGAQCIVRINEPICQCLPGYQGEKCE 1157
Score = 128 bits (322), Expect = 3e-29
Identities = 67/188 (35%), Positives = 95/188 (50%), Gaps = 11/188 (5%)
Query: 1117 INKPQEEQFLKISTNSVVTGCLQLNV--CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHC 1174
+ + +E+ F I + ++NV C N C + C D ++Y C CP ++G+ C
Sbjct: 974 LKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELC 1033
Query: 1175 ELNIDECFS--NPCIHGN-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCIS 1231
E +D C NPC H + C + C C PGY G +C++D D+CQ ++C NGA C
Sbjct: 1034 EEKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTD 1093
Query: 1232 HTNGYSCLCFGNFTGKFCRQSR---LPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPG 1288
NGY+C+C ++G FC S LP T + N C NG C E C C PG
Sbjct: 1094 AVNGYTCICPEGYSGLFCEFSPPMVLPRT---SPCDNFDCQNGAQCIVRINEPICQCLPG 1150
Query: 1289 FTGEWCEK 1296
+ GE CEK
Sbjct: 1151 YQGEKCEK 1158
Score = 112 bits (281), Expect = 2e-24
Identities = 96/388 (24%), Positives = 157/388 (40%), Gaps = 45/388 (11%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE--------EVQWCGFSPCPHGA--- 937
+ C+ N C NG C + ++C CP SG CE C C +GA
Sbjct: 1078 DDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCI 1137
Query: 938 --------QCQPVLQGFECIANAVFNGQSGQILFRSNGNITRELTNITFGFRTRDANVII 989
QC P QG +C N + + + R TNIT T + + I+
Sbjct: 1138 VRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQIPSAKVRPQTNITLQIATDEDSGIL 1197
Query: 990 LHAEKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTS 1049
L+ + + + + + + R+ +G S ++ S++++NDG +H V L L+
Sbjct: 1198 LY-KGDKDHIAVELYRGRVRASYDTG-SHPASAIYSVETINDGNFHIVEL-----LALDQ 1250
Query: 1050 RWQMEVDNETP-FVTSTIATGSLNFLKDNTDIYVGDRAIDNIKGLQGCLSTIEIGGIYLS 1108
+ VD P +T+ +LNF ++ +YVG + G S + G +
Sbjct: 1251 SLSLSVDGGNPKIITNLSKQSTLNF---DSPLYVG-----GMPGKSNVASLRQAPGQNGT 1302
Query: 1109 YFEN-VHGFINKPQEEQFLKISTNS-VVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCP 1166
F + + + F K+ + ++ GC C+ C HG + + C C
Sbjct: 1303 SFHGCIRNLYINSELQDFQKVPMQTGILPGC---EPCHKKVCAHGTCQPSSQAGFTCECQ 1359
Query: 1167 LGWSGKHCELNI-DECFSNPCIHGNCSD-RVAAYHCTCEPGYTGVNCEVDID---NCQSH 1221
GW G C+ D C N C+HG C +Y C C G+ GV C+ + D CQ+
Sbjct: 1360 EGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAI 1419
Query: 1222 QCANGATCISHTNGYSCLCFGNFTGKFC 1249
+C +G +S C C +TG C
Sbjct: 1420 KCKHGKCRLSGLGQPYCECSSGYTGDSC 1447
Score = 108 bits (270), Expect = 4e-23
Identities = 58/165 (35%), Positives = 81/165 (49%), Gaps = 14/165 (8%)
Query: 1181 CFSNPCIH-GNC-SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCI---SHTNG 1235
C SNPC + G C SD V Y CTC G+ G +C+V I C S+ C +G TC +G
Sbjct: 922 CLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDG 981
Query: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
+ C+C F G+ C V ++ + C N C + C+C P +TGE CE
Sbjct: 982 FWCICADGFEGENCE-------VNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCE 1034
Query: 1296 KDIDECASD--PCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
+ +D CA D PC + C F+C C + GE C++D D
Sbjct: 1035 EKLDFCAQDLNPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDD 1079
Score = 81.6 bits (200), Expect = 5e-15
Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 25/188 (13%)
Query: 1162 HCSCPLGW-----SGKHCELNIDECFSNPCIHGNCSDRVA----AYHCTCEPGYTGVNCE 1212
+C C + W ++ E I C + P G +D++ + TC+ G VN
Sbjct: 862 YCDCNMQWLSDWVKSEYKEPGIARC-AGP---GEMADKLLLTTPSKKFTCQ-GPVDVNIL 916
Query: 1213 VDIDNCQSHQCANGATCISH-TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNG 1271
+ C S+ C N TC S + Y C C F G+ C +P C + C +G
Sbjct: 917 AKCNPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCD---VPIHACISNP----CKHG 969
Query: 1272 GNCTEFQTE---LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFA 1328
G C + E C+C GF GE CE ++D+C + C N C D +N + CLC +
Sbjct: 970 GTCHLKEGEEDGFWCICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYT 1029
Query: 1329 GERCEVDL 1336
GE CE L
Sbjct: 1030 GELCEEKL 1037
Score = 67.8 bits (164), Expect = 7e-11
Identities = 53/190 (27%), Positives = 71/190 (37%), Gaps = 14/190 (7%)
Query: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEI-DHDECASSPCQNGAVCQDGIDGYSC 172
C K C HG C C G+ G C+ +D C + C +G YSC
Sbjct: 1336 CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSC 1395
Query: 173 FCVPGYQGRHCDLEVD---ECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEID--- 226
C+ G+ G CD E D C + CK+ L+ +G+ C C Y+G +C+ EI
Sbjct: 1396 KCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRG 1455
Query: 227 ---ECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC---ELNTDECASQPCLHGGLCVDG 280
+ Q A CQ +C G G C + S C G VD
Sbjct: 1456 ERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDE 1515
Query: 281 -ENRYSCNCT 289
E C CT
Sbjct: 1516 VEKVVKCGCT 1525
Score = 67.0 bits (162), Expect = 1e-10
Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 29/280 (10%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESYGD 735
C++ CQ+ +CI C C Y+G C + V+ F +S Y+ +
Sbjct: 1125 CDNFDCQNGAQCIVRINEPICQCLPGYQGEKC-EKLVSVNFINKES--YLQIPSAKVRPQ 1181
Query: 736 TISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLVVKFV--LNDGNV 793
T ++++ + T + SG+LL + + + ++ R R + T + P + V +NDGN
Sbjct: 1182 T-NITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSVETINDGNF 1240
Query: 794 HLISLKIKPYKIELYQSSQNLGFIS--ASTWKIEKGDVIYIGGLPDK-------QETELN 844
H++ L + L N I+ + + +Y+GG+P K Q N
Sbjct: 1241 HIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVASLRQAPGQN 1300
Query: 845 GGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVCHS 904
G F GCI+++ +N++ +F P+ + GC C C +G S
Sbjct: 1301 GTSFHGCIRNLYINSELQDF--------QKVPMQTGILPGC---EPCHKKVCAHGTCQPS 1349
Query: 905 RWDDFSCSCPALTSGKACEE--VQWCGFSPCPHGAQCQPV 942
F+C C G C++ C + C HG C P+
Sbjct: 1350 SQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGT-CLPI 1388
Score = 62.8 bits (151), Expect = 2e-09
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
Query: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV-DECASDPCKNEATCLN-EIGR 207
+ C C +G G++C C G+ G CD D C + C + TCL
Sbjct: 1334 EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVH-GTCLPINAFS 1392
Query: 208 YTCICPHNYSGVNCELEID---ECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Y+C C + GV C+ E D C + C +G LG +C+C+ G+ GD C+
Sbjct: 1393 YSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCD 1448
Score = 59.3 bits (142), Expect = 3e-08
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 7/121 (5%)
Query: 226 DECWSQPCLNGATCQDALGAYF-CDCAPGFLGDHCELNT-DECASQPCLHGGLCVDGENR 283
+ C + C +G TCQ + A F C+C G++G C+ T D C C+HG
Sbjct: 1334 EPCHKKVCAHG-TCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFS 1392
Query: 284 YSCNCTGSGFTGTHC---ETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDL 340
YSC C G G C E L C + C + + C C GYTG C+ ++
Sbjct: 1393 YSCKCL-EGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREI 1451
Query: 341 N 341
+
Sbjct: 1452 S 1452
Score = 57.8 bits (138), Expect = 7e-08
Identities = 34/91 (37%), Positives = 46/91 (50%), Gaps = 8/91 (8%)
Query: 876 PVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWDDF-SCSCPALTSGKACE-EVQWCGFSPC 933
PV VN+ C N C SNPC N G C+S DF C+CP G+ C+ + C +PC
Sbjct: 910 PVDVNILAKC---NPCLSNPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPC 966
Query: 934 PHGAQC---QPVLQGFECIANAVFNGQSGQI 961
HG C + GF CI F G++ ++
Sbjct: 967 KHGGTCHLKEGEEDGFWCICADGFEGENCEV 997
Score = 50.1 bits (118), Expect = 2e-05
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCG--FSPCPHGAQCQPVLQG 945
+ C+ N C N C ++++C CP +G+ CEE + +C +PC H ++C +G
Sbjct: 1000 DDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSKCILTPKG 1059
Query: 946 FECIANAVFNGQSGQILF 963
F+C + G+ I F
Sbjct: 1060 FKCDCTPGYVGEHCDIDF 1077
Score = 50.1 bits (118), Expect = 2e-05
Identities = 46/187 (24%), Positives = 67/187 (35%), Gaps = 73/187 (39%)
Query: 301 LMPLCWSKPCHN----NATCEDSVD-NYTCHCWPGYTGAQCEIDLNE-CNSNPCQSNGEC 354
++P C +PCH + TC+ S +TC C G+ G C+ N+ C N C +G C
Sbjct: 1329 ILPGC--EPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC-VHGTC 1385
Query: 355 VELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCEN 414
+ ++ A Y C C G G+ C+E+ E NPCQ
Sbjct: 1386 LPIN-------------------AFSYSCKCLEGHGGVLCDEE--EDLFNPCQ------- 1417
Query: 415 LPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSG 474
+ C H +C +G P+ C C SG
Sbjct: 1418 ---------------------------AIKCKHGKCRLSGLGQPY---------CECSSG 1441
Query: 475 YTGSLCE 481
YTG C+
Sbjct: 1442 YTGDSCD 1448
Score = 49.3 bits (116), Expect = 3e-05
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 11/111 (9%)
Query: 42 NSTCKDFSKDN-DCSCSDTANNLDKDCDNM-KDPCFSNPC-QGSATCVNTPGERSFLCKC 98
+ TC+ S+ C C + + CD DPC N C G+ +N S+ CKC
Sbjct: 1343 HGTCQPSSQAGFTCECQE--GWMGPLCDQRTNDPCLGNKCVHGTCLPINA---FSYSCKC 1397
Query: 99 PPGYSGTIC---ETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
G+ G +C E C C+HG P C C +GY G C+
Sbjct: 1398 LEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCD 1448
Score = 44.3 bits (103), Expect = 8e-04
Identities = 35/139 (25%), Positives = 54/139 (38%), Gaps = 15/139 (10%)
Query: 1204 PGYTGV--NCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN 1261
P TG+ CE C CA+G S G++C C + G C Q R GN
Sbjct: 1324 PMQTGILPGCEP----CHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQ-RTNDPCLGN 1378
Query: 1262 EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDID---ECASDPCVNGGLCQDLLNK 1318
+ C +G C C G G C+++ D C + C +G L +
Sbjct: 1379 K-----CVHGTCLPINAFSYSCKCLEGHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQ 1433
Query: 1319 FQCLCDVAFAGERCEVDLA 1337
C C + G+ C+ +++
Sbjct: 1434 PYCECSSGYTGDSCDREIS 1452
Score = 34.3 bits (77), Expect = 0.87
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 9/92 (9%)
Query: 29 KNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT 88
+ N CL N C + + + C C + + CD +D NPCQ + C +
Sbjct: 1370 RTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVL--CDEEED--LFNPCQ-AIKCKHG 1424
Query: 89 PGERSFL----CKCPPGYSGTICETTIGSCGK 116
S L C+C GY+G C+ I G+
Sbjct: 1425 KCRLSGLGQPYCECSSGYTGDSCDREISCRGE 1456
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 205 bits (522), Expect = 2e-52
Identities = 183/748 (24%), Positives = 297/748 (39%), Gaps = 142/748 (18%)
Query: 264 DECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNY 323
D C PC +GG C+ R + + +P+ + + +
Sbjct: 3804 DSCVHGPCQNGGSCL---RRLAVSSV------LKSRESLPVI--------IVANEPLQPF 3846
Query: 324 TCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383
C C PGY G+ CEID++EC +PC S G C L G+ C
Sbjct: 3847 LCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNL--------------------VGGFSC 3886
Query: 384 ICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL 443
C GFTG CE D+NEC +PC+NG C+N PG++ C C +T Y G+ C +
Sbjct: 3887 SCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVC------KTGYTGKMCESSVN 3940
Query: 444 GCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTT 503
C C N G+C Q G + C CP G G CE+ S+ + +++ S+
Sbjct: 3941 YCECNPCFNGGSC----QSGVDSYYCHCPFGVFGKHCELN---SYGFEELSYMEFPSLDP 3993
Query: 504 KGSVCNIALRFQTVQPMALLLFR-----SNRDVFVKLELLSGYIHLSIQVNNQSKVLLFI 558
+ I ++F T++ ALLL+ +R F+ LE+ + S + + + L +
Sbjct: 3994 NNNY--IYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYNLGSGTYKLTTM 4051
Query: 559 SHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPV 618
SDG +H V + + +L DSC E T ++ + L P
Sbjct: 4052 K-KVSDGHFHTV-IARRAGMAASLTVDSCSENQEPGYCTV----SNVAVSDDWTLDVQPN 4105
Query: 619 GMTSNGVA----LLNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGCVRKD 674
+T G+ +L + FVGC+ + + N LE + ++ + C R +
Sbjct: 4106 RVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAV--NGRPLEPSQALAAQGILDQCPRLE 4163
Query: 675 W-CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVA---------GRF----GQDD 720
C PCQ G C++ W QC C G C + GR Q++
Sbjct: 4164 GACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSVTPDTALSLEGKGRLDYHMSQNE 4223
Query: 721 STGYVIF-----TLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAML 775
Y++ + E +G SL + RT +G+L+ ++ S+ Y V ++ G++
Sbjct: 4224 KREYLLRQSLRGAMLEPFGVN-SLEVKFRTRSENGVLIHIQESS-NYTTVKIKNGKVYFT 4281
Query: 776 TP---------NSPKLVVK------FVLNDGNVHLISLKIKPYKIELYQSSQNLGFISAS 820
+ N P++ V F++ + + Y ++ +Q+ G +
Sbjct: 4282 SDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDFGGLDVL 4341
Query: 821 TWKIEKGDVIYIGGLPDKQ-ETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNPVLV 879
T I +GG+P Q + F GCI + ++L F + AS++
Sbjct: 4342 T--------ISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPF-SGKHSLASISKTDP 4392
Query: 880 NVTQGCAGDNSCKSNPCHNGGVCHSRW---------------------------DDFSCS 912
+V GC G N C SNPC +C ++W F+CS
Sbjct: 4393 SVKIGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGSCEPGLHSGFTCS 4452
Query: 913 CPALTSGKACEEVQWCGFSPCPHGAQCQ 940
CP +G+ CE V C CP G C+
Sbjct: 4453 CPDSHTGRTCEMVVACLGVLCPQGKVCK 4480
Score = 155 bits (392), Expect = 3e-37
Identities = 68/173 (39%), Positives = 93/173 (53%), Gaps = 22/173 (12%)
Query: 113 SCGKNSCQHGGICHQ---------------------DPIYP-VCICPAGYAGRFCEIDHD 150
SC CQ+GG C + +P+ P +C C GYAG +CEID D
Sbjct: 3805 SCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDID 3864
Query: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 210
EC SPC +G C + + G+SC C G+ GR C+ +++EC PCKN A C N G + C
Sbjct: 3865 ECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNC 3924
Query: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT 263
+C Y+G CE ++ C PC NG +CQ + +Y+C C G G HCELN+
Sbjct: 3925 VCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELNS 3977
Score = 149 bits (376), Expect = 2e-35
Identities = 64/175 (36%), Positives = 90/175 (51%), Gaps = 23/175 (13%)
Query: 147 IDHDECASSPCQNGAVC----------------------QDGIDGYSCFCVPGYQGRHCD 184
+DHD C PCQNG C + + + C C+PGY G C+
Sbjct: 3801 VDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCE 3860
Query: 185 LEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALG 244
+++DEC PC + TC N +G ++C CP ++G CE +I+EC PC NGA CQ+ G
Sbjct: 3861 IDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPG 3920
Query: 245 AYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE 299
++ C C G+ G CE + + C PC +GG C G + Y C+C G G HCE
Sbjct: 3921 SFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCP-FGVFGKHCE 3974
Score = 136 bits (343), Expect = 1e-31
Identities = 64/172 (37%), Positives = 84/172 (48%), Gaps = 20/172 (11%)
Query: 72 DPCFSNPCQGSATCVNTPGERS--------------------FLCKCPPGYSGTICETTI 111
D C PCQ +C+ S FLCKC PGY+G+ CE I
Sbjct: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
Query: 112 GSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYS 171
C + C GG CH C CP G+ GR CE D +EC SPC+NGA+CQ+ ++
Sbjct: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFN 3923
Query: 172 CFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCEL 223
C C GY G+ C+ V+ C +PC N +C + + Y C CP G +CEL
Sbjct: 3924 CVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCEL 3975
Score = 120 bits (301), Expect = 9e-27
Identities = 59/180 (32%), Positives = 82/180 (45%), Gaps = 30/180 (16%)
Query: 1179 DECFSNPCIHG-NCSDRVAA----------------------YHCTCEPGYTGVNCEVDI 1215
D C PC +G +C R+A + C C PGY G CE+DI
Sbjct: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
Query: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275
D C C +G TC + G+SC C FTG+ C + NE C NG C
Sbjct: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDI-------NECLQSPCKNGAICQ 3916
Query: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335
F C+C+ G+TG+ CE ++ C +PC NGG CQ ++ + C C G+ CE++
Sbjct: 3917 NFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELN 3976
Score = 113 bits (282), Expect = 1e-24
Identities = 48/119 (40%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Query: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICH 126
C+ D C +PC TC N G F C CP G++G CE I C ++ C++G IC
Sbjct: 3859 CEIDIDECLPSPCHSGGTCHNLVG--GFSCSCPDGFTGRACERDINECLQSPCKNGAICQ 3916
Query: 127 QDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL 185
P C+C GY G+ CE + C +PC NG CQ G+D Y C C G G+HC+L
Sbjct: 3917 NFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCEL 3975
Score = 108 bits (269), Expect = 5e-23
Identities = 96/370 (25%), Positives = 149/370 (40%), Gaps = 70/370 (18%)
Query: 871 NASLNPVLVNVTQGCAGD------NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE- 923
N L P L G AG + C +PCH+GG CH+ FSCSCP +G+ACE
Sbjct: 3840 NEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACER 3899
Query: 924 EVQWCGFSPCPHGAQCQPVLQGFECIA------------------NAVFNGQSGQILFRS 965
++ C SPC +GA CQ F C+ N FNG S Q S
Sbjct: 3900 DINECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDS 3959
Query: 966 ----------------NGNITRELTNITFG------------FRTRDANVIILH-----A 992
N EL+ + F F T ++ ++L+
Sbjct: 3960 YYCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQT 4019
Query: 993 EKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDPLSQTSRWQ 1052
EFL + I + RL F G+ Y LT+++ V+DG +H V + +
Sbjct: 4020 GDRAEFLALEIAEERLRFSYNLGSGTY--KLTTMKKVSDGHFHTVIARRAGMAASLTVDS 4077
Query: 1053 MEVDNETPFVTSTIATGSLNFLKD---NTDIYVGDRAIDNIKGLQGCLSTIEIGGIYLSY 1109
+ E + T + S ++ D N G R+++ I +G + + + G + +
Sbjct: 4078 CSENQEPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEF 4137
Query: 1110 FENVHGFINKPQEEQFLKISTNSVVTGCLQLN-VCNSNPCLHGGNCEDIYSSYHCSCPLG 1168
N +P E ++ ++ C +L C +PC HGG C D +S C C G
Sbjct: 4138 AVN-----GRPLEPS-QALAAQGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEG 4191
Query: 1169 WSGKHCELNI 1178
+GK+CE ++
Sbjct: 4192 LTGKYCEKSV 4201
Score = 106 bits (264), Expect = 2e-22
Identities = 55/176 (31%), Positives = 79/176 (44%), Gaps = 30/176 (17%)
Query: 1143 CNSNPCLHGGNC----------------------EDIYSSYHCSCPLGWSGKHCELNIDE 1180
C PC +GG+C + + C C G++G CE++IDE
Sbjct: 3806 CVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDE 3865
Query: 1181 CFSNPC-IHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCL 1239
C +PC G C + V + C+C G+TG CE DI+ C C NGA C + ++C+
Sbjct: 3866 CLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCV 3925
Query: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
C +TGK C +S + C C+NGG+C C C G G+ CE
Sbjct: 3926 CKTGYTGKMC-ESSVNYCECN------PCFNGGSCQSGVDSYYCHCPFGVFGKHCE 3974
Score = 103 bits (256), Expect = 2e-21
Identities = 48/135 (35%), Positives = 76/135 (56%), Gaps = 4/135 (2%)
Query: 1118 NKPQEEQFLKISTNSVVTGC-LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL 1176
N+P + K + C + ++ C +PC GG C ++ + CSCP G++G+ CE
Sbjct: 3840 NEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACER 3899
Query: 1177 NIDECFSNPCIHGN-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG 1235
+I+EC +PC +G C + +++C C+ GYTG CE ++ C+ + C NG +C S +
Sbjct: 3900 DINECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDS 3959
Query: 1236 YSCLC-FGNFTGKFC 1249
Y C C FG F GK C
Sbjct: 3960 YYCHCPFGVF-GKHC 3973
Score = 102 bits (254), Expect = 3e-21
Identities = 128/588 (21%), Positives = 232/588 (39%), Gaps = 80/588 (13%)
Query: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDESY 733
++CE PC + G C + SY C C G +C +G ++ + +LD +
Sbjct: 3940 NYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHC----ELNSYGFEELSYMEFPSLDPN- 3994
Query: 734 GDTISLSMFVRTLQPSGLLLALENST-----YQYIRVWLERGRLAM-LTPNSPKLVVKFV 787
+ F + LL +N T + + + ER R + L + KL
Sbjct: 3995 -NNYIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYNLGSGTYKLTTMKK 4053
Query: 788 LNDGNVHLISLK----IKPYKIELYQSSQNLGFISAST------WKIE-KGDVIYIGGLP 836
++DG+ H + + ++ +Q G+ + S W ++ + + + +GG+
Sbjct: 4054 VSDGHFHTVIARRAGMAASLTVDSCSENQEPGYCTVSNVAVSDDWTLDVQPNRVTVGGIR 4113
Query: 837 DKQETELNGGF-----FKGCIQDVRLNNQNLEFFPNPTNNASLNPVLVNVTQGCAGDNSC 891
+ G F GCI + +N + LE P+ + +L Q + +C
Sbjct: 4114 SLEPILQRRGHVESHDFVGCIMEFAVNGRPLE----PSQALAAQGIL---DQCPRLEGAC 4166
Query: 892 KSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIAN 951
+PC +GG C W C C +GK CE+ S P A L+G +
Sbjct: 4167 TRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEK------SVTPDTALS---LEGKGRLDY 4217
Query: 952 AVFNGQSGQILFRSN--GNITRE--LTNITFGFRTRDANVIILHAEKEPEFLNISIQDSR 1007
+ + + L R + G + + ++ FRTR N +++H ++ + + I++ +
Sbjct: 4218 HMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLIHIQESSNYTTVKIKNGK 4277
Query: 1008 LFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDP---LSQTSRWQMEVDNETP-FVT 1063
++F +G + + V DG WH + LS + ++ + T F
Sbjct: 4278 VYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDFGG 4337
Query: 1064 STIATGSLNFLKDNTDIYVGDRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEE 1123
+ T SL + N A G GC++++ GG L F H + + +
Sbjct: 4338 LDVLTISLGGIPPNQAHRDAQTA-----GFDGCIASMWYGGESLP-FSGKHSLASISKTD 4391
Query: 1124 QFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFS 1183
+KI GC N+C SNPC C + + +Y C P +C S
Sbjct: 4392 PSVKI-------GCRGPNICASNPCWGDLLCINQWYAYRCVPP------------GDCAS 4432
Query: 1184 NPCIH-GNCSDRV-AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATC 1229
+PC + G+C + + + C+C +TG CE+ + C C G C
Sbjct: 4433 HPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEM-VVACLGVLCPQGKVC 4479
Score = 89.4 bits (220), Expect = 2e-17
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 4/124 (3%)
Query: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
S+C + CL + C + TC + CSC D + C+ + C +PC+ A
Sbjct: 3857 SWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTG--RACERDINECLQSPCKNGAI 3914
Query: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
C N PG SF C C GY+G +CE+++ C N C +GG C C CP G G+
Sbjct: 3915 CQNFPG--SFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKH 3972
Query: 145 CEID 148
CE++
Sbjct: 3973 CELN 3976
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 9/124 (7%)
Query: 116 KNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGI-DGYSCFC 174
K C+ IC +P + +C + C + +CAS PCQNG C+ G+ G++C C
Sbjct: 4395 KIGCRGPNICASNPCWGDLLCINQWYAYRC-VPPGDCASHPCQNGGSCEPGLHSGFTCSC 4453
Query: 175 VPGYQGRHCDLEVDECASDPCKNEATC-LNEIGRYTCICPHNYSGVNCELEIDECWSQPC 233
+ GR C++ V C C C + C+ ++ L W+ P
Sbjct: 4454 PDSHTGRTCEMVV-ACLGVLCPQGKVCKAGSPAGHVCVLSQGPEEISLPL-----WAVPA 4507
Query: 234 LNGA 237
+ G+
Sbjct: 4508 IVGS 4511
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 14/92 (15%)
Query: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF-C 248
CAS+PC + C+N+ Y C+ P +C S PC NG +C+ L + F C
Sbjct: 4404 CASNPCWGDLLCINQWYAYRCVPP------------GDCASHPCQNGGSCEPGLHSGFTC 4451
Query: 249 DCAPGFLGDHCELNTDECASQPCLHGGLCVDG 280
C G CE+ C C G +C G
Sbjct: 4452 SCPDSHTGRTCEM-VVACLGVLCPQGKVCKAG 4482
Score = 50.1 bits (118), Expect = 2e-05
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 19/107 (17%)
Query: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP- 132
C SNPC G C+N + + +C P G C + CQ+GG C + ++
Sbjct: 4404 CASNPCWGDLLCIN----QWYAYRCVPP----------GDCASHPCQNGGSC-EPGLHSG 4448
Query: 133 -VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID-GYSCFCVPG 177
C CP + GR CE+ C C G VC+ G G+ C G
Sbjct: 4449 FTCSCPDSHTGRTCEM-VVACLGVLCPQGKVCKAGSPAGHVCVLSQG 4494
Score = 49.7 bits (117), Expect = 2e-05
Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 21/109 (19%)
Query: 390 TGIHCEE-DVNECSSNPCQNGGTC-------------ENLPGNYTCH---CPFDNLSRTF 432
+G+ E D + C PCQNGG+C E+LP + PF
Sbjct: 3794 SGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPG 3853
Query: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Y G C + C C + GTC H G GFSC CP G+TG CE
Sbjct: 3854 YAGSWCEIDIDECLPSPCHSGGTC--HNLVG--GFSCSCPDGFTGRACE 3898
Score = 40.4 bits (93), Expect = 0.012
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 23/93 (24%)
Query: 889 NSCKSNPCHNGGVCHSRW----------------------DDFSCSCPALTSGKACE-EV 925
+SC PC NGG C R F C C +G CE ++
Sbjct: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
Query: 926 QWCGFSPCPHGAQCQPVLQGFECIANAVFNGQS 958
C SPC G C ++ GF C F G++
Sbjct: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRA 3896
Score = 40.4 bits (93), Expect = 0.012
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 2/49 (4%)
Query: 251 APGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE 299
A G L D C C PC HGG C+D + C+C G TG +CE
Sbjct: 4152 AQGIL-DQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCK-EGLTGKYCE 4198
Score = 40.0 bits (92), Expect = 0.016
Identities = 15/40 (37%), Positives = 21/40 (52%)
Query: 107 CETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
C G+C ++ CQHGG C + C C G G++CE
Sbjct: 4159 CPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
Score = 39.3 bits (90), Expect = 0.027
Identities = 13/35 (37%), Positives = 22/35 (62%)
Query: 1264 TNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
T C +GG C ++ + +C C+ G TG++CEK +
Sbjct: 4167 TRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSV 4201
Score = 38.1 bits (87), Expect = 0.060
Identities = 14/36 (38%), Positives = 18/36 (50%)
Query: 152 CASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
C SPCQ+G C D C C G G++C+ V
Sbjct: 4166 CTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSV 4201
Score = 37.7 bits (86), Expect = 0.078
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 1300 ECASDPCVNGGLCQDLLNK-FQCLCDVAFAGERCEVDLA 1337
+CAS PC NGG C+ L+ F C C + G CE+ +A
Sbjct: 4429 DCASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVA 4467
Score = 37.4 bits (85), Expect = 0.10
Identities = 15/45 (33%), Positives = 21/45 (46%)
Query: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNE 1262
C C +G TC+ + + C C TGK+C +S P T E
Sbjct: 4166 CTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSVTPDTALSLE 4210
Score = 37.4 bits (85), Expect = 0.10
Identities = 40/178 (22%), Positives = 63/178 (35%), Gaps = 36/178 (20%)
Query: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTE- 1276
C S+ C CI+ Y C +P C + C NGG+C
Sbjct: 4404 CASNPCWGDLLCINQWYAYRC---------------VPPGDCASH----PCQNGGSCEPG 4444
Query: 1277 FQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
+ C C TG CE + C C G +C+ + AG C +
Sbjct: 4445 LHSGFTCSCPDSHTGRTCEM-VVACLGVLCPQGKVCK----------AGSPAGHVCVLSQ 4493
Query: 1337 ADDLIS----DIFTTIGSVTVALLLILLLAIVASVVTSNK-RATQGTYSPSRQEKEGS 1389
+ IS + +GS L L++L I+ + K + + P ++K+GS
Sbjct: 4494 GPEEISLPLWAVPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGS 4551
Score = 36.2 bits (82), Expect = 0.23
Identities = 15/46 (32%), Positives = 20/46 (43%)
Query: 1294 CEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADD 1339
C + C PC +GG C D + QC C G+ CE + D
Sbjct: 4159 CPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSVTPD 4204
Score = 34.3 bits (77), Expect = 0.87
Identities = 13/33 (39%), Positives = 15/33 (45%)
Query: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
C PC +G TC D C C G G +CE
Sbjct: 4166 CTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
Score = 32.7 bits (73), Expect = 2.5
Identities = 14/52 (26%), Positives = 24/52 (46%), Gaps = 2/52 (3%)
Query: 60 ANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTI 111
A + C ++ C +PCQ TC++ + C C G +G CE ++
Sbjct: 4152 AQGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQ--CHCKEGLTGKYCEKSV 4201
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 197 bits (500), Expect = 8e-50
Identities = 97/264 (36%), Positives = 133/264 (50%), Gaps = 17/264 (6%)
Query: 86 VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPV-CICPAGYAGRF 144
+ TP ++ F C+ PP + + C + CQ+ G CH DP+ C CP+GY GR
Sbjct: 905 LTTPAKK-FECQGPPTLA---VQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRD 960
Query: 145 CEIDHDECASSPCQNGAVC--QDGIDG-YSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
CE+ D C+S PC+NG C Q+G D ++C C G++G C + D+C C N C
Sbjct: 961 CEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVC 1020
Query: 202 LNEIGRYTCICPHNYSGVNCELEIDECWSQ--PCLNGATCQDALGAYFCDCAPGFLGDHC 259
++ +G YTC CP Y G CE +D C PC + A C C+C PG+ GD+C
Sbjct: 1021 VDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNC 1080
Query: 260 ELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPL------CWSKPCHNN 313
N D+C C +G C+D N YSC C G++G CE L C C N
Sbjct: 1081 SENQDDCRDHRCQNGAQCMDEVNSYSCLCA-EGYSGQLCEIPPHLPAPKSPCEGTECQNG 1139
Query: 314 ATCEDSVDNYTCHCWPGYTGAQCE 337
A C D + C C PG+ G +CE
Sbjct: 1140 ANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 194 bits (492), Expect = 7e-49
Identities = 95/243 (39%), Positives = 124/243 (51%), Gaps = 15/243 (6%)
Query: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICH----Q 127
D C S+PCQ TC N P E + C CP GY G CE ++ SC C++GG CH +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLE-VYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGE 985
Query: 128 DPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
D + C CP G+ G C ++ D+C C NG VC DG+ Y+C C Y+G+ C+ V
Sbjct: 986 DAPF-TCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLV 1044
Query: 188 DECASD--PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGA 245
D C+ D PC++EA C+ C C Y+G NC D+C C NGA C D + +
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNS 1104
Query: 246 YFCDCAPGFLGDHCEL------NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE 299
Y C CA G+ G CE+ C C +G CVD NR C C GF G CE
Sbjct: 1105 YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCL-PGFGGPECE 1163
Query: 300 TLM 302
L+
Sbjct: 1164 KLL 1166
Score = 182 bits (462), Expect = 2e-45
Identities = 144/525 (27%), Positives = 225/525 (42%), Gaps = 70/525 (13%)
Query: 222 ELEIDECWSQPCLNGATCQ-DALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLC--V 278
+ + D C S PC N TC D L Y C C G+ G CE++ D C+S PC +GG C
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 279 DGENR-YSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCE 337
+GE+ ++C+C +GF G C C C N C D V NYTC C Y G CE
Sbjct: 983 EGEDAPFTCSCP-TGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACE 1041
Query: 338 --IDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE 395
+DL + NPCQ +CV G P G C C PG+ G +C
Sbjct: 1042 QLVDLCSPDLNPCQHEAQCV------------GTPD--------GPRCECMPGYAGDNCS 1081
Query: 396 EDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS------DILLGCTHQQ 449
E+ ++C + CQNG C + +Y+C C Y G+ C C +
Sbjct: 1082 ENQDDCRDHRCQNGAQCMDEVNSYSCLCAEG------YSGQLCEIPPHLPAPKSPCEGTE 1135
Query: 450 CLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSF-EGDGFLWVKSGSVTTKGSVC 508
C N C+ D + C C G+ G CE +++F + D +L +
Sbjct: 1136 CQNGANCV----DQGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRA--- 1188
Query: 509 NIALRFQTVQPMALLLFRSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISHNTSDGEWH 568
NI L+ T + +LL+ + D + +EL G++ +S + ++ + +DG++H
Sbjct: 1189 NITLQVSTAEDNGILLYNGDND-HIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFH 1247
Query: 569 FVEVI-FAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVAL 627
VE++ F + V L++ S L S+ + ++GG+PV + S A
Sbjct: 1248 TVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPL------YVGGMPVDVNS---AA 1298
Query: 628 LNFYNMPSTPSFVGCLQDIKIDWNHITLENISSGSSLNVKAGC--VRKDWCESQPCQSRG 685
+ + + F GC++++ I N+ + + V GC RK +C CQ
Sbjct: 1299 FRLWQILNGTGFHGCIRNLYI--NNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNA 1356
Query: 686 ------RCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGY 724
C W+ CD +P +GP + V G+ D+ Y
Sbjct: 1357 TPGPMCHCEAGWVGLHCD--QPADGPCHGHKCVHGQCVPLDALSY 1399
Score = 170 bits (431), Expect = 8e-42
Identities = 87/237 (36%), Positives = 113/237 (47%), Gaps = 12/237 (5%)
Query: 34 CLSNSCQNNSTC-KDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGER 92
CLS+ CQN TC D + C+C +DC+ D C S PC+ TC GE
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKG--RDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 93 S-FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDE 151
+ F C CP G+ G C C ++C +GG+C C CP Y G+ CE D
Sbjct: 987 APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1046
Query: 152 CAS--SPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
C+ +PCQ+ A C DG C C+PGY G +C D+C C+N A C++E+ Y+
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 210 CICPHNYSGVNCEL------EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
C+C YSG CE+ C C NGA C D C C PGF G CE
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 148 bits (373), Expect = 4e-35
Identities = 66/199 (33%), Positives = 100/199 (50%), Gaps = 10/199 (5%)
Query: 1141 NVCNSNPCLHGGNCE-DIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNC----SDRV 1195
++C S+PC + G C D Y C+CP G+ G+ CE+++D C S PC +G
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
A + C+C G+ G C V+ D+C H CANG C+ Y+C C + GK C Q
Sbjct: 987 APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQL--- 1043
Query: 1256 STVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDL 1315
+C + C + C +C C PG+ G+ C ++ D+C C NG C D
Sbjct: 1044 VDLCSPDLN--PCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDE 1101
Query: 1316 LNKFQCLCDVAFAGERCEV 1334
+N + CLC ++G+ CE+
Sbjct: 1102 VNSYSCLCAEGYSGQLCEI 1120
Score = 130 bits (328), Expect = 7e-30
Identities = 68/209 (32%), Positives = 90/209 (43%), Gaps = 11/209 (5%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCK-DFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQG 81
K C + C S C+N TC +D +CS C D C + C
Sbjct: 957 KGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACAN 1016
Query: 82 SATCVNTPGERSFLCKCPPGYSGTICETTIGSCGK--NSCQHGGICHQDPIYPVCICPAG 139
CV+ G ++ C+CP Y G CE + C N CQH C P P C C G
Sbjct: 1017 GGVCVDGVG--NYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPG 1074
Query: 140 YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDL------EVDECASD 193
YAG C + D+C CQNGA C D ++ YSC C GY G+ C++ C
Sbjct: 1075 YAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGT 1134
Query: 194 PCKNEATCLNEIGRYTCICPHNYSGVNCE 222
C+N A C+++ R C C + G CE
Sbjct: 1135 ECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 129 bits (325), Expect = 2e-29
Identities = 64/158 (40%), Positives = 79/158 (50%), Gaps = 6/158 (3%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFS--NPCIH-GNCSDRVAAYH 1199
C + C +GG C D +Y C CPL + GK CE +D C NPC H C
Sbjct: 1009 CVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPR 1068
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR-QSRLPSTV 1258
C C PGY G NC + D+C+ H+C NGA C+ N YSCLC ++G+ C LP+
Sbjct: 1069 CECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPK 1128
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK 1296
E T C NG NC + C C PGF G CEK
Sbjct: 1129 SPCEGTE--CQNGANCVDQGNRPVCQCLPGFGGPECEK 1164
Score = 120 bits (300), Expect = 1e-26
Identities = 106/411 (25%), Positives = 156/411 (37%), Gaps = 72/411 (17%)
Query: 884 GCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-------EVQWCGF 930
G AGDN C+ + C NG C + +SC C SG+ CE C
Sbjct: 1074 GYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEG 1133
Query: 931 SPCPHGA-----------QCQPVLQGFEC--IANAVFNGQSGQILFRSNGNITRELTNIT 977
+ C +GA QC P G EC + + F + + F N R NIT
Sbjct: 1134 TECQNGANCVDQGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPR--ANIT 1191
Query: 978 FGFRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEV 1037
T + N I+L+ + + + + + + G S+ ++ S +++NDG +H V
Sbjct: 1192 LQVSTAEDNGILLY-NGDNDHIAVELYQGHVRVSYDPG-SYPSSAIYSAETINDGQFHTV 1249
Query: 1038 TLSMTDPLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVGDRAID--------- 1088
L D + S +D +P G L +YVG +D
Sbjct: 1250 ELVAFDQMVNLS-----IDGGSPMTMDNF--GKHYTLNSEAPLYVGGMPVDVNSAAFRLW 1302
Query: 1089 ---NIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNS 1145
N G GC+ + +IN ++ VV GC C
Sbjct: 1303 QILNGTGFHGCIRNL---------------YINNELQDFTKTQMKPGVVPGC---EPCRK 1344
Query: 1146 NPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNID-ECFSNPCIHGNCSDRVA-AYHCTCE 1203
CLHG + C C GW G HC+ D C + C+HG C A +Y C C+
Sbjct: 1345 LYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQ 1404
Query: 1204 PGYTGVNCE---VDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
GY+G C + C+ QC +G S T G C+C F+G+ C Q
Sbjct: 1405 DGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQ 1455
Score = 93.2 bits (230), Expect = 2e-18
Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 14/167 (8%)
Query: 1179 DECFSNPCIH-GNC-SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG- 1235
D C S+PC + G C +D + Y C C GY G +CEV +D+C S C NG TC +
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 1236 --YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW 1293
++C C F G C V ++ + C NGG C + C C + G+
Sbjct: 987 APFTCSCPTGFEGPTCG-------VNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 1294 CEKDIDECASD--PCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
CE+ +D C+ D PC + C + +C C +AG+ C + D
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDD 1086
Score = 68.2 bits (165), Expect = 5e-11
Identities = 52/187 (27%), Positives = 70/187 (37%), Gaps = 21/187 (11%)
Query: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTI-GSCGKNSCQHGGICHQDPIYP 132
C CQ +AT PG +C C G+ G C+ G C + C HG D +
Sbjct: 1347 CLHGICQPNAT----PGP---MCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSY 1399
Query: 133 VCICPAGYAGRFCEIDH---DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
C C GY+G C + C C +G G G C C PG+ G C+ E E
Sbjct: 1400 SCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-SE 1458
Query: 190 CASDPCKNEATCLNEIGRYTCIC--PHNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
C DP ++ +++ R IC S V C C Q C G + +
Sbjct: 1459 CRGDPVRD----FHQVQRGYAICQTTRPLSWVECR---GSCPGQGCCQGLRLKRRKFTFE 1511
Query: 248 CDCAPGF 254
C F
Sbjct: 1512 CSDGTSF 1518
Score = 59.3 bits (142), Expect = 3e-08
Identities = 76/358 (21%), Positives = 132/358 (36%), Gaps = 61/358 (17%)
Query: 673 KDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYVIFTLDES 732
K CE CQ+ C++ C C + GP C + ++ F D+ Y+ FT D
Sbjct: 1128 KSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPEC-EKLLSVNFVDRDT--YLQFT-DLQ 1183
Query: 733 YGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAML----TPNSPKLVVKFVL 788
++++ V T + +G+L L N +I V L +G + + + S + +
Sbjct: 1184 NWPRANITLQVSTAEDNGIL--LYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETI 1241
Query: 789 NDGNVHLISLKIKPYKIELY------QSSQNLGFISASTWKIEKGDVIYIGGLPDKQETE 842
NDG H + L + L + N G + + +Y+GG+P +
Sbjct: 1242 NDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFG----KHYTLNSEAPLYVGGMPVDVNSA 1297
Query: 843 -------LNGGFFKGCIQDVRLNNQNLEFFPNPTN----------------------NAS 873
LNG F GCI+++ +NN+ +F NA+
Sbjct: 1298 AFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNAT 1357
Query: 874 LNPVLVNVTQGCAG-------DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-- 924
P + + G G D C + C +G +SC C SG C +
Sbjct: 1358 PGP-MCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAG 1416
Query: 925 --VQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFRSNGNITRELTNITFGF 980
+ C C HG +G C+ + F+G+ + G+ R+ + G+
Sbjct: 1417 ALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDPVRDFHQVQRGY 1474
Score = 58.9 bits (141), Expect = 3e-08
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 5/125 (4%)
Query: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD-ECASDPCKNEATCLNEIGRY 208
+ C C +G + G C C G+ G HCD D C C + + Y
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSY 1399
Query: 209 TCICPHNYSGVNCELE---IDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDE 265
+C C YSG C + C CL+G C C PGF G+ CE E
Sbjct: 1400 SCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCE-QESE 1458
Query: 266 CASQP 270
C P
Sbjct: 1459 CRGDP 1463
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/188 (26%), Positives = 73/188 (38%), Gaps = 66/188 (35%)
Query: 226 DECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYS 285
+ C CL+G +A C C G++G HC D+ A PC HG CV G+
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHC----DQPADGPC-HGHKCVHGQ---- 1390
Query: 286 CNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNS 345
C L L +Y+C C GY+GA C N+ +
Sbjct: 1391 ------------CVPLDAL-----------------SYSCQCQDGYSGALC----NQAGA 1417
Query: 346 --NPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV---CICQPGFTGIHCEEDVNE 400
PC+ GL + +ASG C+C PGF+G CE++ +E
Sbjct: 1418 LAEPCR------------------GLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-SE 1458
Query: 401 CSSNPCQN 408
C +P ++
Sbjct: 1459 CRGDPVRD 1466
Score = 52.0 bits (123), Expect = 4e-06
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCG--FSPCPHGAQCQPVLQG 945
+ C + C NGGVC +++C CP GKACE+ V C +PC H AQC G
Sbjct: 1007 DDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDG 1066
Query: 946 FEC 948
C
Sbjct: 1067 PRC 1069
Score = 50.4 bits (119), Expect = 1e-05
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 16/107 (14%)
Query: 380 GYVCICQPGFTGIHCEEDVN-ECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDC 438
G +C C+ G+ G+HC++ + C + C +G +Y+C C + Y G C
Sbjct: 1359 GPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQC------QDGYSGALC 1412
Query: 439 SD---ILLGCTHQQCLNNGTCIPHFQ-DGQHGFSCLCPSGYTGSLCE 481
+ + C QCL+ H Q G G C+C G++G LCE
Sbjct: 1413 NQAGALAEPCRGLQCLHG-----HCQASGTKGAHCVCDPGFSGELCE 1454
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Query: 889 NSCKSNPCHNGGVCHSRWDD---FSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQ 944
+SC S PC NGG CH++ + F+CSCP G C C C +G C +
Sbjct: 966 DSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVG 1025
Query: 945 GFECIANAVFNGQS 958
+ C + G++
Sbjct: 1026 NYTCQCPLQYEGKA 1039
Score = 45.1 bits (105), Expect = 5e-04
Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 891 CKSNPCHNGGVCHS-RWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQC 939
C S+PC N G CH+ + + C+CP+ G+ CE + C PC +G C
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTC 979
Score = 44.7 bits (104), Expect = 6e-04
Identities = 30/119 (25%), Positives = 44/119 (36%), Gaps = 9/119 (7%)
Query: 1218 CQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEF 1277
C+ C +G + T G C C + G C Q C K C +G
Sbjct: 1342 CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPA--DGPCHGHK----CVHGQCVPLD 1395
Query: 1278 QTELKCMCRPGFTGEWCEKD---IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
C C+ G++G C + + C C++G C+CD F+GE CE
Sbjct: 1396 ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
Score = 34.7 bits (78), Expect = 0.66
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)
Query: 401 CSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF 460
C C +G N CHC + G C G H +G C+P
Sbjct: 1342 CRKLYCLHGICQPNATPGPMCHC------EAGWVGLHCDQPADGPCHGHKCVHGQCVPL- 1394
Query: 461 QDGQHGFSCLCPSGYTGSLCEIATTLS 487
+SC C GY+G+LC A L+
Sbjct: 1395 --DALSYSCQCQDGYSGALCNQAGALA 1419
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 192 bits (488), Expect = 2e-48
Identities = 176/650 (27%), Positives = 263/650 (40%), Gaps = 83/650 (12%)
Query: 339 DLNECNSNPCQSNGECVELSSEKQYGRITGLPSSF--SYHEASGYVCICQPGFTGIHCEE 396
D N C PC++ CV + S H G C C PGFTG +CE
Sbjct: 1228 DDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTGDYCET 1287
Query: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG--CTHQQCLNNG 454
+V+ C S PC G C + G YTC C R Y G C CT C N G
Sbjct: 1288 EVDLCYSRPCGPHGRCRSREGGYTCLC------RDGYTGEHCEVSARSGRCTPGVCKNGG 1341
Query: 455 TCIPHFQDGQHGFSCLCPSG-YTGSLCEIATTLSFEGDGFLWVKSGSVTTKGSVCNIALR 513
TC+ GF C CPSG + C++ TT SF F+ + + +AL
Sbjct: 1342 TCVNLLVG---GFKCDCPSGDFEKPYCQV-TTRSFPAHSFITFRG---LRQRFHFTLALS 1394
Query: 514 FQTVQPMALLLFR---SNRDVFVKLELLSGYIHLSIQV-NNQSKVLLFISHNTSDGEWHF 569
F T + LLL+ + + FV LE++ + L+ + + V F+ SDG+WH
Sbjct: 1395 FATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHT 1454
Query: 570 VEVIF---------------AEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLG 614
V++ + +E + D C + + L + CA Q + G
Sbjct: 1455 VQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGSVLGNYS--CAAQGT-QG 1511
Query: 615 GLPVGMTSNGVALLNFYNMPSTP--------SFVGCLQDIKIDWNHITLENISSGSSLNV 666
G + G LL +P P FVGC++++++D HI + + + +
Sbjct: 1512 GSKKSLDLTGPLLLG--GVPDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANN--GT 1567
Query: 667 KAGC-VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV 725
GC +K+ C+S C + G C+N W ++ C+C + G +C +E + S
Sbjct: 1568 VPGCPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFLGSSL-VA 1626
Query: 726 IFTLDESYGDTISLSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLVVK 785
L LS+ RT Q G+LL I + L G + ML+ L
Sbjct: 1627 WHGLSLPISQPWYLSLMFRTRQADGVLLQAITRGRSTITLQLREGHV-MLSVEGTGLQAS 1685
Query: 786 FV------LNDGNVHLISLKI----KPYKIEL---YQSSQNLGFISASTWKIEKGDVIYI 832
+ NDG+ H L + P L Y + G + + + I +
Sbjct: 1686 SLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSN-ITV 1744
Query: 833 GGLPDKQETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASLNP---VLVNVTQGCAGDN 889
GG+P G F+GC+Q VR+++ P SL+P +NV QGC+ +
Sbjct: 1745 GGIPGPAGGVARG--FRGCLQGVRVSD-------TPEGVNSLDPSHGESINVEQGCSLPD 1795
Query: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
C SNPC C + WD +SCSC G C V C +PC H + C
Sbjct: 1796 PCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCTNV--CDLNPCEHQSVC 1843
Score = 127 bits (319), Expect = 8e-29
Identities = 173/708 (24%), Positives = 271/708 (38%), Gaps = 162/708 (22%)
Query: 672 RKDWCESQPCQSRGRCINLWLS-YQCDCHR-PYEGPNC---LREYVAGRFGQDDSTGYVI 726
R C C++ G C+NL + ++CDC +E P C R + A F +
Sbjct: 1328 RSGRCTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQVTTRSFPAHSF--------IT 1379
Query: 727 FT-LDESYGDTISLSMFVRTLQPSGLLLAL----ENSTYQYIRVWLERGRLAMLTPNSPK 781
F L + + T++LS T + GLLL E + + V E+ +L S
Sbjct: 1380 FRGLRQRFHFTLALSF--ATKERDGLLLYNGRFNEKHDFVALEVIQEQVQLTFSAGESTT 1437
Query: 782 LVVKFV---LNDGNVHLISLKI--KPYK----IELYQSSQNLGFISA------------- 819
V FV ++DG H + LK KP + S Q + ++
Sbjct: 1438 TVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPSEQKVAVVTVDGCDTGVALRFGS 1497
Query: 820 ---------------STWKIEKGDVIYIGGLPDKQET-ELNGGFFKGCIQDVRLNNQNLE 863
S ++ + +GG+PD E+ + F GC++++++++++++
Sbjct: 1498 VLGNYSCAAQGTQGGSKKSLDLTGPLLLGGVPDLPESFPVRMRQFVGCMRNLQVDSRHID 1557
Query: 864 FFPNPTNNASLNPVLVNVTQGC-AGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
NN ++ GC A N C SN CHNGG C ++WD FSC CP GK+C
Sbjct: 1558 MADFIANNGTV--------PGCPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSC 1609
Query: 923 EEVQWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFRSNGNITRELTNITFGFRT 982
AQ Q F + ++G S I + ++ FRT
Sbjct: 1610 --------------AQEMANPQHFLGSSLVAWHGLSLPI---------SQPWYLSLMFRT 1646
Query: 983 RDANVIILHAEKEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQS---------VNDGT 1033
R A+ ++L A I+ S + QL+ G+ + T LQ+ NDG
Sbjct: 1647 RQADGVLLQA--------ITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGD 1698
Query: 1034 WHEVTLSMTDP-------LSQTSRWQMEVDNETPFV----TSTIATGSLNFLKDNTDIYV 1082
WH L++ LS Q N P + S I G +
Sbjct: 1699 WHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGG-----------I 1747
Query: 1083 GDRAIDNIKGLQGCLSTIEIGGIY--LSYFENVHGFINKPQEEQFLKISTNSVVTGCLQL 1140
A +G +GCL + + ++ + HG + +V GC
Sbjct: 1748 PGPAGGVARGFRGCLQGVRVSDTPEGVNSLDPSHG-------------ESINVEQGCSLP 1794
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAA-- 1197
+ C+SNPC C + + SY CSC G+ G +C + C NPC H + C+ + +A
Sbjct: 1795 DPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNC---TNVCDLNPCEHQSVCTRKPSAPH 1851
Query: 1198 -YHCTCEPGYTGVNCEVDIDN-CQ----SHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Y C C P Y G CE ID C H C + G+ C N T C
Sbjct: 1852 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNC-DVSKGFDPDC--NKTSGECHC 1908
Query: 1252 SRLPSTVCGNEKTNL-TCYNGGNCTEF--QTELKCMCRPGFTGEWCEK 1296
G+ L CY G+ + + +C C+PG G C++
Sbjct: 1909 KENHYRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIGRQCDR 1956
Score = 89.7 bits (221), Expect = 2e-17
Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 54/217 (24%)
Query: 150 DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGR-- 207
D C S+PC + C + D YSC C PGY G +C + C +PC++++ C +
Sbjct: 1795 DPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNC---TNVCDLNPCEHQSVCTRKPSAPH 1851
Query: 208 -YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
YTC CP NY G CE ID QPC G G CD + GF D C + EC
Sbjct: 1852 GYTCECPPNYLGPYCETRID----QPCPRGWWGHPTCGPCNCDVSKGFDPD-CNKTSGEC 1906
Query: 267 ASQPCLHGGLCVDGENRYS---------CNCTGSGFTGTHCETLMPLCWSKPCHNNATCE 317
+ EN Y C+C +G C+
Sbjct: 1907 HCK-----------ENHYRPPGSPTCLLCDCYPTGSLSRVCDP----------------- 1938
Query: 318 DSVDNYTCHCWPGYTGAQCEIDLN---ECNSNPCQSN 351
++ C C PG G QC+ N E +N C+ N
Sbjct: 1939 ---EDGQCPCKPGVIGRQCDRCDNPFAEVTTNGCEVN 1972
Score = 82.4 bits (202), Expect = 3e-15
Identities = 47/149 (31%), Positives = 63/149 (42%), Gaps = 26/149 (17%)
Query: 141 AGRFCEIDHDECASSPCQNGAVCQD----------------------GIDGYSCFCVPGY 178
A R D + C PC+N C + G C C PG+
Sbjct: 1221 AQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGF 1280
Query: 179 QGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI--DECWSQPCLNG 236
G +C+ EVD C S PC C + G YTC+C Y+G +CE+ C C NG
Sbjct: 1281 TGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNG 1340
Query: 237 ATCQDAL-GAYFCDCAPG-FLGDHCELNT 263
TC + L G + CDC G F +C++ T
Sbjct: 1341 GTCVNLLVGGFKCDCPSGDFEKPYCQVTT 1369
Score = 82.0 bits (201), Expect = 4e-15
Identities = 38/93 (40%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
Query: 1163 CSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYHCTCEPGYTGVNCEVDI--DNCQ 1219
C CP G++G +CE +D C+S PC HG C R Y C C GYTG +CEV C
Sbjct: 1274 CRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCT 1333
Query: 1220 SHQCANGATCIS-HTNGYSCLC-FGNFTGKFCR 1250
C NG TC++ G+ C C G+F +C+
Sbjct: 1334 PGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQ 1366
Score = 79.3 bits (194), Expect = 2e-14
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 7/92 (7%)
Query: 129 PIYPV----CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD 184
PI+PV C CP G+ G +CE + D C S PC C+ GY+C C GY G HC+
Sbjct: 1265 PIHPVGGLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCE 1324
Query: 185 LEV--DECASDPCKNEATCLN-EIGRYTCICP 213
+ C CKN TC+N +G + C CP
Sbjct: 1325 VSARSGRCTPGVCKNGGTCVNLLVGGFKCDCP 1356
Score = 78.2 bits (191), Expect = 5e-14
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 25/135 (18%)
Query: 190 CASDPCKNEATC----------------------LNEIGRYTCICPHNYSGVNCELEIDE 227
C +PC+N C ++ +G C CP ++G CE E+D
Sbjct: 1232 CLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGGLRCRCPPGFTGDYCETEVDL 1291
Query: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN--TDECASQPCLHGGLCVD-GENRY 284
C+S+PC C+ G Y C C G+ G+HCE++ + C C +GG CV+ +
Sbjct: 1292 CYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGF 1351
Query: 285 SCNCTGSGFTGTHCE 299
C+C F +C+
Sbjct: 1352 KCDCPSGDFEKPYCQ 1366
Score = 76.6 bits (187), Expect = 2e-13
Identities = 78/334 (23%), Positives = 129/334 (38%), Gaps = 66/334 (19%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE---EVQWCGFSPCPHGAQCQPVLQG-F 946
C S PC G C SR ++C C +G+ CE C C +G C +L G F
Sbjct: 1292 CYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGF 1351
Query: 947 EC-IANAVFNGQSGQILFRS---------NGNITRELTNITFGFRTRDANVIILHA---E 993
+C + F Q+ RS G R + F T++ + ++L+
Sbjct: 1352 KCDCPSGDFEKPYCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFN 1411
Query: 994 KEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTDP--LSQTSRW 1051
++ +F+ + + ++ +G S +S V+DG WH V L + L QT
Sbjct: 1412 EKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLP 1471
Query: 1052 QMEVDNETPFVT-------------------STIATGSLNFLKDNTDIYVGDRAIDNIKG 1092
Q + + VT S A G+ K + D+ G + +
Sbjct: 1472 QGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKKSLDL-TGPLLLGGVPD 1530
Query: 1093 LQ-----------GCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGC-LQL 1140
L GC+ +++ ++ + I+ N V GC +
Sbjct: 1531 LPESFPVRMRQFVGCMRNLQVDSRHIDMAD---------------FIANNGTVPGCPAKK 1575
Query: 1141 NVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHC 1174
NVC+SN C +GG C + + ++ C CPLG+ GK C
Sbjct: 1576 NVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSC 1609
Score = 76.6 bits (187), Expect = 2e-13
Identities = 63/216 (29%), Positives = 86/216 (39%), Gaps = 36/216 (16%)
Query: 62 NLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQH 121
N+++ C ++ DPC SNPC ++ C N S+ C C PGY G C C N C+H
Sbjct: 1786 NVEQGC-SLPDPCDSNPCPANSYCSN--DWDSYSCSCDPGYYGDNCTNV---CDLNPCEH 1839
Query: 122 GGICHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGY 178
+C + P P C CP Y G +CE D+ PC G +C G+
Sbjct: 1840 QSVCTRKPSAPHGYTCECPPNYLGPYCETRIDQ----PCPRGWWGHPTCGPCNCDVSKGF 1895
Query: 179 QGRHCDLEVDECASDPCK-------NEATCLNEIGRYTCIC-PHNYSGVNCELEIDECWS 230
C+ EC CK TCL C C P C+ E +C
Sbjct: 1896 D-PDCNKTSGEC---HCKENHYRPPGSPTCL------LCDCYPTGSLSRVCDPEDGQCPC 1945
Query: 231 QPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC 266
+P + G C D F + + CE+N D C
Sbjct: 1946 KPGVIGRQC-DRCDNPFAEVTT----NGCEVNYDSC 1976
Score = 70.1 bits (170), Expect = 1e-11
Identities = 31/74 (41%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 286 CNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDL--NEC 343
C C GFTG +CET + LC+S+PC + C YTC C GYTG CE+ C
Sbjct: 1274 CRCP-PGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRC 1332
Query: 344 NSNPCQSNGECVEL 357
C++ G CV L
Sbjct: 1333 TPGVCKNGGTCVNL 1346
Score = 68.2 bits (165), Expect = 5e-11
Identities = 36/103 (34%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRL 1254
V C C PG+TG CE ++D C S C C S GY+CLC +TG+ C S
Sbjct: 1269 VGGLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVS-- 1326
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQT-ELKCMCRPG-FTGEWCE 1295
T C NGG C KC C G F +C+
Sbjct: 1327 ---ARSGRCTPGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQ 1366
Score = 66.6 bits (161), Expect = 2e-10
Identities = 63/209 (30%), Positives = 79/209 (37%), Gaps = 43/209 (20%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGE-R 92
C SN C NS C + CSC DN + C NPC+ + C P
Sbjct: 1797 CDSNPCPANSYCSNDWDSYSCSCDPGYYG-----DNCTNVCDLNPCEHQSVCTRKPSAPH 1851
Query: 93 SFLCKCPPGYSGTICETTI------GSCGKNSCQHGGICHQD---PIYPVCICPAGYAGR 143
+ C+CPP Y G CET I G G +C G C+ D P C +G
Sbjct: 1852 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTC---GPCNCDVSKGFDPDCNKTSGEC-- 1906
Query: 144 FCEIDHDECASSPCQNGAVCQDGIDGYSCFCVP-GYQGRHCDLEVDECASDPCKNEATCL 202
C+ +H SP C C C P G R CD E +C PCK
Sbjct: 1907 HCKENHYRPPGSP-----TC------LLCDCYPTGSLSRVCDPEDGQC---PCKP----- 1947
Query: 203 NEIGRYTCICPHNYSGV---NCELEIDEC 228
IGR C + ++ V CE+ D C
Sbjct: 1948 GVIGRQCDRCDNPFAEVTTNGCEVNYDSC 1976
Score = 66.6 bits (161), Expect = 2e-10
Identities = 57/194 (29%), Positives = 76/194 (39%), Gaps = 52/194 (26%)
Query: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
C S PC N+ C + D+Y+C C PGY G C N C+ NPC+ C
Sbjct: 1797 CDSNPCPANSYCSNDWDSYSCSCDPGYYGDNCT---NVCDLNPCEHQSVC---------- 1843
Query: 365 RITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGG---------TCENL 415
T PS+ GY C C P + G +CE +++ PC G C+
Sbjct: 1844 --TRKPSA-----PHGYTCECPPNYLGPYCETRIDQ----PCPRGWWGHPTCGPCNCDVS 1892
Query: 416 PG-----NYT---CHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGF 467
G N T CHC ++ G C +L C L+ C P +DGQ
Sbjct: 1893 KGFDPDCNKTSGECHCKENHYRPP--GSPTC--LLCDCYPTGSLSR-VCDP--EDGQ--- 1942
Query: 468 SCLCPSGYTGSLCE 481
C C G G C+
Sbjct: 1943 -CPCKPGVIGRQCD 1955
Score = 65.9 bits (159), Expect = 3e-10
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 96 CKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEID--HDECA 153
C+CPPG++G CET + C C G C C+C GY G CE+ C
Sbjct: 1274 CRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCT 1333
Query: 154 SSPCQNGAVCQD-GIDGYSCFCVPG-YQGRHCDL 185
C+NG C + + G+ C C G ++ +C +
Sbjct: 1334 PGVCKNGGTCVNLLVGGFKCDCPSGDFEKPYCQV 1367
Score = 63.2 bits (152), Expect = 2e-09
Identities = 25/54 (46%), Positives = 33/54 (61%)
Query: 1281 LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
L+C C PGFTG++CE ++D C S PC G C+ + CLC + GE CEV
Sbjct: 1272 LRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEV 1325
Score = 51.6 bits (122), Expect = 5e-06
Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 10/97 (10%)
Query: 1230 ISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF 1289
I G C C FTG +C +C + C G C + C+CR G+
Sbjct: 1266 IHPVGGLRCRCPPGFTGDYCETE---VDLCYSRP----CGPHGRCRSREGGYTCLCRDGY 1318
Query: 1290 TGEWCEKDI--DECASDPCVNGGLCQDLL-NKFQCLC 1323
TGE CE C C NGG C +LL F+C C
Sbjct: 1319 TGEHCEVSARSGRCTPGVCKNGGTCVNLLVGGFKCDC 1355
Score = 48.1 bits (113), Expect = 6e-05
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTI--GSCGKNSCQHGGI 124
C+ D C+S PC C + G + C C GY+G CE + G C C++GG
Sbjct: 1285 CETEVDLCYSRPCGPHGRCRSREG--GYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGT 1342
Query: 125 CHQDPIYPV-CICPAG-YAGRFCEI 147
C + C CP+G + +C++
Sbjct: 1343 CVNLLVGGFKCDCPSGDFEKPYCQV 1367
Score = 41.6 bits (96), Expect = 0.005
Identities = 31/114 (27%), Positives = 43/114 (37%), Gaps = 19/114 (16%)
Query: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275
D C S+ C + C + + YSC C + G C + VC C + CT
Sbjct: 1795 DPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNC------TNVCDLNP----CEHQSVCT 1844
Query: 1276 EFQTE---LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVA 1326
+ C C P + G +CE ID+ PC G C CDV+
Sbjct: 1845 RKPSAPHGYTCECPPNYLGPYCETRIDQ----PCPRGWWGHPTCG--PCNCDVS 1892
Score = 39.3 bits (90), Expect = 0.027
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 175 VPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI 225
VPG C + + C S+ C N TC+N+ ++C CP + G +C E+
Sbjct: 1568 VPG-----CPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEM 1613
Score = 38.5 bits (88), Expect = 0.046
Identities = 15/45 (33%), Positives = 24/45 (53%)
Query: 1294 CEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
C + C S+ C NGG C + + F C C + F G+ C ++A+
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEMAN 1615
Score = 38.1 bits (87), Expect = 0.060
Identities = 15/43 (34%), Positives = 22/43 (51%)
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
C + C S+ C NG C + D +SC C G+ G+ C E+
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSCAQEM 1613
Score = 38.1 bits (87), Expect = 0.060
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 67 CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTIC 107
C K+ C SN C TCVN +F C+CP G+ G C
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQ--WDAFSCECPLGFGGKSC 1609
Score = 37.4 bits (85), Expect = 0.10
Identities = 14/39 (35%), Positives = 19/39 (48%)
Query: 298 CETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC 336
C +C S CHN TC + D ++C C G+ G C
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSC 1609
Score = 36.6 bits (83), Expect = 0.17
Identities = 22/89 (24%), Positives = 29/89 (32%), Gaps = 2/89 (2%)
Query: 26 FCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC 85
+C C S C + C+ C C D + C C+ TC
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGTC 1343
Query: 86 VNTPGERSFLCKCPPG-YSGTICETTIGS 113
VN F C CP G + C+ T S
Sbjct: 1344 VNLL-VGGFKCDCPSGDFEKPYCQVTTRS 1371
Score = 35.8 bits (81), Expect = 0.30
Identities = 15/39 (38%), Positives = 20/39 (51%)
Query: 221 CELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC 259
C + + C S C NG TC + A+ C+C GF G C
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSC 1609
Score = 33.9 bits (76), Expect = 1.1
Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 103 SGTI--CETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC 145
+GT+ C C N+C +GG C C CP G+ G+ C
Sbjct: 1565 NGTVPGCPAKKNVCDSNTCHNGGTCVNQWDAFSCECPLGFGGKSC 1609
Score = 33.5 bits (75), Expect = 1.5
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 1/40 (2%)
Query: 259 CELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHC 298
C + C S C +GG CV+ + +SC C GF G C
Sbjct: 1571 CPAKKNVCDSNTCHNGGTCVNQWDAFSCECP-LGFGGKSC 1609
Score = 33.1 bits (74), Expect = 1.9
Identities = 11/34 (32%), Positives = 17/34 (50%)
Query: 1299 DECASDPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
D C S+PC C + + + C CD + G+ C
Sbjct: 1795 DPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNC 1828
Score = 32.7 bits (73), Expect = 2.5
Identities = 12/32 (37%), Positives = 17/32 (53%)
Query: 1267 TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
TC+NGG C C C GF G+ C +++
Sbjct: 1582 TCHNGGTCVNQWDAFSCECPLGFGGKSCAQEM 1613
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 187 bits (476), Expect = 5e-47
Identities = 169/655 (25%), Positives = 267/655 (40%), Gaps = 89/655 (13%)
Query: 339 DLNECNSNPCQSNGECVEL----SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
D N C PC++ +CV + SS T L H +G C C PGFTG +C
Sbjct: 1303 DDNICLREPCENYMKCVSVLRFDSSAPFLSSTTVLFRPI--HPINGLRCRCPPGFTGDYC 1360
Query: 395 EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS-DILLG-CTHQQCLN 452
E +++ C S+PC G C + G YTC C D + G C D G C + C N
Sbjct: 1361 ETEIDLCYSDPCGANGRCRSREGGYTCECFED------FTGEHCEVDARSGRCANGVCKN 1414
Query: 453 NGTCIPHFQDGQHGFSCLCPSG-YTGSLCEIATTLSFEGDGFLWVKSGSVTTKGSVCNIA 511
GTC+ GF C+CP G Y CE+ TT SF F+ + + I+
Sbjct: 1415 GGTCVNLLIG---GFHCVCPPGEYERPYCEV-TTRSFPPQSFVTFRG---LRQRFHFTIS 1467
Query: 512 LRFQTVQPMALLLFR---SNRDVFVKLELLSGYIHLSIQV-NNQSKVLLFISHNTSDGEW 567
L F T + LLL+ + + F+ LE++ + L+ + V + SDG W
Sbjct: 1468 LTFATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAGETTTTVAPKVPSGVSDGRW 1527
Query: 568 HFVEVIF----------------AEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNS 611
H V+V + E + + +DD C + + + CA Q +
Sbjct: 1528 HSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVDD-CDTTMAVRFGKDIGNYS--CAAQGT 1584
Query: 612 FLGGLPVGMTSNGVALLNFYNMPS-----TPSFVGCLQDIKIDWNHITLENISSGSSLNV 666
G + + L N+P FVGC++++ +D ++ + + +
Sbjct: 1585 QTGSKKSLDLTGPLLLGGVPNLPEDFPVHNRQFVGCMRNLSVDGKNVDMAGFIANN--GT 1642
Query: 667 KAGC-VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV 725
+ GC R+++C+ + CQ+ G C+N W Y C+C + G NC + + +S V
Sbjct: 1643 REGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHPQLFSGES---V 1699
Query: 726 IFTLDESYGDTIS--LSMFVRTLQPSGLLLALENSTYQYIRVWLERGRLAMLTPNSPKLV 783
+ D + ++ L + RT + +L+ + R+ + L + P V
Sbjct: 1700 VSWSDLNIIISVPWYLGLMFRTRKEDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDV 1759
Query: 784 VKFVLN-----DGNVHLISLKIKPYKIEL-----------YQSSQNLGFISASTWKIEKG 827
+L+ DG H + +++K K + Y QN I +
Sbjct: 1760 ESVMLSGLRVTDGEWHHLLIELKNVKEDSEMKHLVTMTLDYGMDQNKADIGGMLPGLTVR 1819
Query: 828 DVIYIGGLPDKQETELNGGFFKGCIQDVRLNNQNLEFFPNPTNNASL---NPVLVNVTQG 884
V+ G DK F+GC+Q VR+ PTN A+L N + V V G
Sbjct: 1820 SVVVGGASEDKVSVRRG---FRGCMQGVRMGG-------TPTNVATLNMNNALKVRVKDG 1869
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
C D+ C S+PC CH W+D+SC C G C V C +PC + C
Sbjct: 1870 CDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC--VDACHLNPCENMGAC 1922
Score = 118 bits (295), Expect = 5e-26
Identities = 162/704 (23%), Positives = 268/704 (38%), Gaps = 150/704 (21%)
Query: 672 RKDWCESQPCQSRGRCINLWLS-YQCDCHR-PYEGPNCLREYVAGRFGQDDSTGYVIFT- 728
R C + C++ G C+NL + + C C YE P C E F +V F
Sbjct: 1403 RSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYC--EVTTRSFPPQS---FVTFRG 1457
Query: 729 LDESYGDTISLSMFVRTLQPSGLLL--ALENSTYQYIRVWL--ERGRLAMLTPNSPKLVV 784
L + + TISL+ T + +GLLL N + +I + + E+ +L + V
Sbjct: 1458 LRQRFHFTISLTF--ATQERNGLLLYNGRFNEKHDFIALEIVDEQVQLTFSAGETTTTVA 1515
Query: 785 KFV---LNDGNVHLISLKI--KPYKIEL------------------------YQSSQNLG 815
V ++DG H + ++ KP L + +++G
Sbjct: 1516 PKVPSGVSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVDDCDTTMAVRFGKDIG 1575
Query: 816 FISASTWKIEKGDV--------IYIGGLPDKQET-ELNGGFFKGCIQDVRLNNQNLEFFP 866
S + + G + +GG+P+ E ++ F GC++++ ++ +N++
Sbjct: 1576 NYSCAAQGTQTGSKKSLDLTGPLLLGGVPNLPEDFPVHNRQFVGCMRNLSVDGKNVDMAG 1635
Query: 867 NPTNNASLNPVLVNVTQGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV 925
NN + +GCA N C C NGG C +RW+ + C CP GK CE+
Sbjct: 1636 FIANNGT--------REGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCEQA 1687
Query: 926 QWCGFSPCPHGAQCQPVLQGFECIANAVFNGQSGQILFRSNGNITRELT-NITFGFRTRD 984
PH +F+G+S ++ S+ NI + + FRTR
Sbjct: 1688 M-------PHPQ---------------LFSGES--VVSWSDLNIIISVPWYLGLMFRTRK 1723
Query: 985 ANVIILHAEKE-PEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTD 1043
+ +++ A P + I ++ L F++ G S + S V DG WH + + + +
Sbjct: 1724 EDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDVESVMLSGLRVTDGEWHHLLIELKN 1783
Query: 1044 PLSQTSRWQMEVDNETP-FVTSTIATGSLNFLKDN---------TDIYVGDRAIDNI--- 1090
++ D+E VT T+ G D + VG + D +
Sbjct: 1784 ---------VKEDSEMKHLVTMTLDYGMDQNKADIGGMLPGLTVRSVVVGGASEDKVSVR 1834
Query: 1091 KGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLH 1150
+G +GC+ + +GG + + LK+ V GC + C S+PC
Sbjct: 1835 RGFRGCMQGVRMGGTPTN--------VATLNMNNALKVR---VKDGCDVDDPCTSSPCPP 1883
Query: 1151 GGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNC---SDRVAAYHCTCEPGY 1206
C D + Y C C G+ G +C +D C NPC + G C Y C C P +
Sbjct: 1884 NSRCHDAWEDYSCVCDKGYLGINC---VDACHLNPCENMGACVRSPGSPQGYVCECGPSH 1940
Query: 1207 TGVNCEVDID-----------NCQSHQCANGA---TCISHTNGYSCLCFGNFTGKFCRQS 1252
G CE +D C CA + TNG C C N+ + +
Sbjct: 1941 YGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCNKTNG-QCQCKENYYKLLAQDT 1999
Query: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK 1296
LP + + TC +C C+PG G C +
Sbjct: 2000 CLPCDCFPHGSHSRTCDMATG--------QCACKPGVIGRQCNR 2035
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/147 (31%), Positives = 66/147 (44%), Gaps = 26/147 (17%)
Query: 143 RFCEIDHDECASSPCQNGAVCQD----------------------GIDGYSCFCVPGYQG 180
R D + C PC+N C I+G C C PG+ G
Sbjct: 1298 RVLPFDDNICLREPCENYMKCVSVLRFDSSAPFLSSTTVLFRPIHPINGLRCRCPPGFTG 1357
Query: 181 RHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI--DECWSQPCLNGAT 238
+C+ E+D C SDPC C + G YTC C +++G +CE++ C + C NG T
Sbjct: 1358 DYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCANGVCKNGGT 1417
Query: 239 CQDAL-GAYFCDCAPG-FLGDHCELNT 263
C + L G + C C PG + +CE+ T
Sbjct: 1418 CVNLLIGGFHCVCPPGEYERPYCEVTT 1444
Score = 81.6 bits (200), Expect = 5e-15
Identities = 39/103 (37%), Positives = 55/103 (53%), Gaps = 8/103 (7%)
Query: 129 PIYPV----CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD 184
PI+P+ C CP G+ G +CE + D C S PC C+ GY+C C + G HC+
Sbjct: 1340 PIHPINGLRCRCPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCE 1399
Query: 185 LEV--DECASDPCKNEATCLN-EIGRYTCIC-PHNYSGVNCEL 223
++ CA+ CKN TC+N IG + C+C P Y CE+
Sbjct: 1400 VDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEV 1442
Score = 81.6 bits (200), Expect = 5e-15
Identities = 71/233 (30%), Positives = 93/233 (39%), Gaps = 47/233 (20%)
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
C++D D C SSPC + C D + YSC C GY G +C VD C +PC+N C+
Sbjct: 1870 CDVD-DPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC---VDACHLNPCENMGACVRS 1925
Query: 205 IGR---YTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
G Y C C ++ G CE ++D PC G G C + GF D +
Sbjct: 1926 PGSPQGYVCECGPSHYGPYCENKLD----LPCPRGWWGNPVCGPCHCAVSKGFDPDCNKT 1981
Query: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPL-CWSKPCHNNATCEDSV 320
N G C EN Y +T +P C+ H+ TC+ +
Sbjct: 1982 N------------GQCQCKENYYKLLAQ---------DTCLPCDCFPHGSHSR-TCDMAT 2019
Query: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSF 373
C C PG G QC N C+ NP E L E Y G P +F
Sbjct: 2020 GQ--CACKPGVIGRQC----NRCD-NPF---AEVTTLGCEVIY---NGCPKAF 2059
Score = 77.0 bits (188), Expect = 1e-13
Identities = 36/92 (39%), Positives = 51/92 (55%), Gaps = 5/92 (5%)
Query: 1163 CSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAYHCTCEPGYTGVNCEVDI--DNCQ 1219
C CP G++G +CE ID C+S+PC +G C R Y C C +TG +CEVD C
Sbjct: 1349 CRCPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCA 1408
Query: 1220 SHQCANGATCIS-HTNGYSCLC-FGNFTGKFC 1249
+ C NG TC++ G+ C+C G + +C
Sbjct: 1409 NGVCKNGGTCVNLLIGGFHCVCPPGEYERPYC 1440
Score = 75.1 bits (183), Expect = 4e-13
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 23/117 (19%)
Query: 282 NRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDL- 340
N C C GFTG +CET + LC+S PC N C YTC C+ +TG CE+D
Sbjct: 1345 NGLRCRCP-PGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDAR 1403
Query: 341 -NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPG-FTGIHCE 395
C + C++ G CV L G+ C+C PG + +CE
Sbjct: 1404 SGRCANGVCKNGGTCVNLL-------------------IGGFHCVCPPGEYERPYCE 1441
Score = 74.3 bits (181), Expect = 8e-13
Identities = 56/189 (29%), Positives = 75/189 (39%), Gaps = 44/189 (23%)
Query: 305 CWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYG 364
C S PC N+ C D+ ++Y+C C GY G C ++ C+ NPC++ G CV
Sbjct: 1876 CTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC---VDACHLNPCENMGACV--------- 1923
Query: 365 RITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP 424
R G P GYVC C P G +CE ++ PC G + G CHC
Sbjct: 1924 RSPGSPQ--------GYVCECGPSHYGPYCENKLD----LPCPRGWWGNPVCG--PCHCA 1969
Query: 425 ----FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIP--HFQDGQHGFS-------CLC 471
FD G C + + + L TC+P F G H + C C
Sbjct: 1970 VSKGFDPDCNKTNGQCQCKE-----NYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCAC 2024
Query: 472 PSGYTGSLC 480
G G C
Sbjct: 2025 KPGVIGRQC 2033
Score = 72.8 bits (177), Expect = 2e-12
Identities = 49/153 (32%), Positives = 64/153 (41%), Gaps = 21/153 (13%)
Query: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
C +PC+N C++ + R+ P S I +NG C+
Sbjct: 1307 CLREPCENYMKCVSVL-RFDSSAPFLSSTTVLFRPIHP------INGLRCR--------- 1350
Query: 250 CAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCE--TLMPLCWS 307
C PGF GD+CE D C S PC G C E Y+C C FTG HCE C +
Sbjct: 1351 CPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECF-EDFTGEHCEVDARSGRCAN 1409
Query: 308 KPCHNNATCED-SVDNYTCHCWPG-YTGAQCEI 338
C N TC + + + C C PG Y CE+
Sbjct: 1410 GVCKNGGTCVNLLIGGFHCVCPPGEYERPYCEV 1442
Score = 72.0 bits (175), Expect = 4e-12
Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 74 CFSNPCQGSATCVNT---PGERSFL-----------------CKCPPGYSGTICETTIGS 113
C PC+ CV+ FL C+CPPG++G CET I
Sbjct: 1307 CLREPCENYMKCVSVLRFDSSAPFLSSTTVLFRPIHPINGLRCRCPPGFTGDYCETEIDL 1366
Query: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEID--HDECASSPCQNGAVCQD-GIDGY 170
C + C G C C C + G CE+D CA+ C+NG C + I G+
Sbjct: 1367 CYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGF 1426
Query: 171 SCFCVPG-YQGRHCDL 185
C C PG Y+ +C++
Sbjct: 1427 HCVCPPGEYERPYCEV 1442
Score = 72.0 bits (175), Expect = 4e-12
Identities = 38/98 (38%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
Query: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
C C PG+TG CE +ID C S C C S GY+C CF +FTG+ C + S C
Sbjct: 1349 CRCPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHC-EVDARSGRC 1407
Query: 1260 GNEKTNLTCYNGGNCTEFQT-ELKCMCRPG-FTGEWCE 1295
N C NGG C C+C PG + +CE
Sbjct: 1408 ANG----VCKNGGTCVNLLIGGFHCVCPPGEYERPYCE 1441
Score = 69.7 bits (169), Expect = 2e-11
Identities = 74/336 (22%), Positives = 129/336 (38%), Gaps = 68/336 (20%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE---EVQWCGFSPCPHGAQCQPVL-QGF 946
C S+PC G C SR ++C C +G+ CE C C +G C +L GF
Sbjct: 1367 CYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGF 1426
Query: 947 ECIAN-AVFNGQSGQILFRS---------NGNITRELTNITFGFRTRDANVIILHA---E 993
C+ + ++ RS G R I+ F T++ N ++L+
Sbjct: 1427 HCVCPPGEYERPYCEVTTRSFPPQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFN 1486
Query: 994 KEPEFLNISIQDSRLFFQLQSGNSFYMLSLTSLQSVNDGTWHEVTLSMTD---------- 1043
++ +F+ + I D ++ +G + ++ V+DG WH V + +
Sbjct: 1487 EKHDFIALEIVDEQVQLTFSAGETTTTVAPKVPSGVSDGRWHSVQVQYYNKPNIGHLGLP 1546
Query: 1044 ----------------PLSQTSRWQMEVDNETPFVTSTIATGSLNFLKDNTDIYVG---- 1083
+ R+ ++ N + T TGS L + +G
Sbjct: 1547 HGPSGEKMAVVTVDDCDTTMAVRFGKDIGNYSCAAQGT-QTGSKKSLDLTGPLLLGGVPN 1605
Query: 1084 ---DRAIDNIKGLQGCLSTIEIGGIYLSYFENVHGFINKPQEEQFLKISTNSVVTGC-LQ 1139
D + N + GC+ + + G + ++ GF I+ N GC +
Sbjct: 1606 LPEDFPVHN-RQFVGCMRNLSVDGKNV----DMAGF-----------IANNGTREGCAAR 1649
Query: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCE 1175
N C+ C +GG C + ++ Y C CPL + GK+CE
Sbjct: 1650 RNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCE 1685
Score = 68.9 bits (167), Expect = 3e-11
Identities = 56/206 (27%), Positives = 78/206 (37%), Gaps = 37/206 (17%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGE-R 92
C S+ C NS C D +D C C + N D C NPC+ CV +PG +
Sbjct: 1876 CTSSPCPPNSRCHDAWEDYSCVCDKGYLGI-----NCVDACHLNPCENMGACVRSPGSPQ 1930
Query: 93 SFLCKCPPGYSGTICETTI------GSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
++C+C P + G CE + G G C G CH C G+ C
Sbjct: 1931 GYVCECGPSHYGPYCENKLDLPCPRGWWGNPVC---GPCH-------CAVSKGF-DPDCN 1979
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVP-GYQGRHCDLEVDECASDPCKNEATCLNEI 205
+ +C + QD C C P G R CD+ +CA P I
Sbjct: 1980 KTNGQCQCKENYYKLLAQDTC--LPCDCFPHGSHSRTCDMATGQCACKP--------GVI 2029
Query: 206 GRYTCICPHNYSGV---NCELEIDEC 228
GR C + ++ V CE+ + C
Sbjct: 2030 GRQCNRCDNPFAEVTTLGCEVIYNGC 2055
Score = 68.6 bits (166), Expect = 4e-11
Identities = 32/77 (41%), Positives = 41/77 (53%)
Query: 1281 LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
L+C C PGFTG++CE +ID C SDPC G C+ + C C F GE CEVD
Sbjct: 1347 LRCRCPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGR 1406
Query: 1341 ISDIFTTIGSVTVALLL 1357
++ G V LL+
Sbjct: 1407 CANGVCKNGGTCVNLLI 1423
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 42/202 (20%)
Query: 65 KDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGI 124
KD ++ DPC S+PC ++ C + + C C GY G C + +C N C++ G
Sbjct: 1867 KDGCDVDDPCTSSPCPPNSRCHD--AWEDYSCVCDKGYLGINC---VDACHLNPCENMGA 1921
Query: 125 CHQDPIYP---VCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGR 181
C + P P VC C + G +CE D PC G C G+
Sbjct: 1922 CVRSPGSPQGYVCECGPSHYGPYCENKLD----LPCPRGWWGNPVCGPCHCAVSKGF--- 1974
Query: 182 HCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCL----NGA 237
DP N+ C C NY + L D C C +
Sbjct: 1975 -----------DPDCNKT-------NGQCQCKENYYKL---LAQDTCLPCDCFPHGSHSR 2013
Query: 238 TCQDALGAYFCDCAPGFLGDHC 259
TC A G C C PG +G C
Sbjct: 2014 TCDMATGQ--CACKPGVIGRQC 2033
Score = 55.5 bits (132), Expect = 4e-07
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 29/92 (31%)
Query: 336 CEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA-SGYVCICQPGFTGIHC 394
C++D + C S+PC N C H+A Y C+C G+ GI+C
Sbjct: 1870 CDVD-DPCTSSPCPPNSRC---------------------HDAWEDYSCVCDKGYLGINC 1907
Query: 395 EEDVNECSSNPCQNGGTCENLPGN---YTCHC 423
V+ C NPC+N G C PG+ Y C C
Sbjct: 1908 ---VDACHLNPCENMGACVRSPGSPQGYVCEC 1936
Score = 55.1 bits (131), Expect = 5e-07
Identities = 33/93 (35%), Positives = 41/93 (44%), Gaps = 10/93 (10%)
Query: 1234 NGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEW 1293
NG C C FTG +C +C ++ C G C + C C FTGE
Sbjct: 1345 NGLRCRCPPGFTGDYCETE---IDLCYSDP----CGANGRCRSREGGYTCECFEDFTGEH 1397
Query: 1294 CEKDI--DECASDPCVNGGLCQDLL-NKFQCLC 1323
CE D CA+ C NGG C +LL F C+C
Sbjct: 1398 CEVDARSGRCANGVCKNGGTCVNLLIGGFHCVC 1430
Score = 52.4 bits (124), Expect = 3e-06
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 11/83 (13%)
Query: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSD----- 1193
++++C S+PC G C Y C C ++G+HCE+ + S C +G C +
Sbjct: 1363 EIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEV---DARSGRCANGVCKNGGTCV 1419
Query: 1194 --RVAAYHCTCEPG-YTGVNCEV 1213
+ +HC C PG Y CEV
Sbjct: 1420 NLLIGGFHCVCPPGEYERPYCEV 1442
Score = 50.4 bits (119), Expect = 1e-05
Identities = 63/308 (20%), Positives = 115/308 (37%), Gaps = 60/308 (19%)
Query: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTK 504
C ++C N GTC+ + + + C CP + G CE A G V +
Sbjct: 1653 CDGRRCQNGGTCVNRW----NMYLCECPLRFGGKNCEQAMPHPQLFSGESVVSWSDLNII 1708
Query: 505 GSV-CNIALRFQTVQPMALLL-FRSNRDVFVKLELLSGYIHLSIQVNNQSKVLLFISH-N 561
SV + L F+T + ++L+ S +L++L+ Y+ + + +S
Sbjct: 1709 ISVPWYLGLMFRTRKEDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDVESVMLSGLR 1768
Query: 562 TSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLPVGMT 621
+DGEWH + + L + + + K + DQ+ + +GG+ G+T
Sbjct: 1769 VTDGEWHHL------LIELKNVKEDSEMKHLVTMTLDYGMDQN-----KADIGGMLPGLT 1817
Query: 622 SNGVAL--LNFYNMPSTPSFVGCLQDIKIDWN--HITLENISSGSSLNVKAGCVRKDWCE 677
V + + + F GC+Q +++ ++ N+++ + VK GC D C
Sbjct: 1818 VRSVVVGGASEDKVSVRRGFRGCMQGVRMGGTPTNVATLNMNNALKVRVKDGCDVDDPCT 1877
Query: 678 SQPC-----------------------------------QSRGRCINLWLS---YQCDCH 699
S PC ++ G C+ S Y C+C
Sbjct: 1878 SSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCECG 1937
Query: 700 RPYEGPNC 707
+ GP C
Sbjct: 1938 PSHYGPYC 1945
Score = 45.8 bits (107), Expect = 3e-04
Identities = 26/89 (29%), Positives = 33/89 (37%), Gaps = 2/89 (2%)
Query: 26 FCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC 85
+C C S+ C N C+ C C + + D C + C+ TC
Sbjct: 1359 YCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRCANGVCKNGGTC 1418
Query: 86 VNTPGERSFLCKCPPG-YSGTICETTIGS 113
VN F C CPPG Y CE T S
Sbjct: 1419 VNLL-IGGFHCVCPPGEYERPYCEVTTRS 1446
Score = 38.1 bits (87), Expect = 0.060
Identities = 15/40 (37%), Positives = 19/40 (47%)
Query: 183 CDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222
C + C C+N TC+N Y C CP + G NCE
Sbjct: 1646 CAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCE 1685
Score = 37.4 bits (85), Expect = 0.10
Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 12/73 (16%)
Query: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
G TN+ N N LK + G C+ D D C S PC C D +
Sbjct: 1847 GGTPTNVATLNMNNA------LKVRVKDG-----CDVD-DPCTSSPCPPNSRCHDAWEDY 1894
Query: 1320 QCLCDVAFAGERC 1332
C+CD + G C
Sbjct: 1895 SCVCDKGYLGINC 1907
Score = 37.0 bits (84), Expect = 0.13
Identities = 16/44 (36%), Positives = 21/44 (47%)
Query: 1290 TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
T E C + C C NGG C + N + C C + F G+ CE
Sbjct: 1642 TREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCE 1685
Score = 36.6 bits (83), Expect = 0.17
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 259 CELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMP 303
C + C + C +GG CV+ N Y C C F G +CE MP
Sbjct: 1646 CAARRNFCDGRRCQNGGTCVNRWNMYLCECP-LRFGGKNCEQAMP 1689
Score = 35.4 bits (80), Expect = 0.39
Identities = 18/62 (29%), Positives = 24/62 (38%)
Query: 276 LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQ 335
L VDG+N + T C C + C N TC + + Y C C + G
Sbjct: 1624 LSVDGKNVDMAGFIANNGTREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKN 1683
Query: 336 CE 337
CE
Sbjct: 1684 CE 1685
Score = 35.4 bits (80), Expect = 0.39
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 6/73 (8%)
Query: 1264 TNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC---QDLLNKFQ 1320
T+ C C + + C+C G+ G C +D C +PC N G C +
Sbjct: 1877 TSSPCPPNSRCHDAWEDYSCVCDKGYLGINC---VDACHLNPCENMGACVRSPGSPQGYV 1933
Query: 1321 CLCDVAFAGERCE 1333
C C + G CE
Sbjct: 1934 CECGPSHYGPYCE 1946
Score = 34.7 bits (78), Expect = 0.66
Identities = 15/47 (31%), Positives = 22/47 (46%)
Query: 214 HNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
+N + C + C + C NG TC + Y C+C F G +CE
Sbjct: 1639 NNGTREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCE 1685
Score = 34.3 bits (77), Expect = 0.87
Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 61 NNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICE 108
N + C ++ C CQ TCVN +LC+CP + G CE
Sbjct: 1640 NGTREGCAARRNFCDGRRCQNGGTCVNR--WNMYLCECPLRFGGKNCE 1685
Score = 30.8 bits (68), Expect = 9.6
Identities = 13/40 (32%), Positives = 17/40 (42%)
Query: 107 CETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
C C CQ+GG C +C CP + G+ CE
Sbjct: 1646 CAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCE 1685
Score = 30.8 bits (68), Expect = 9.6
Identities = 12/40 (30%), Positives = 19/40 (47%)
Query: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD 184
C + C CQNG C + + Y C C + G++C+
Sbjct: 1646 CAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFGGKNCE 1685
>gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 184 bits (468), Expect = 4e-46
Identities = 95/240 (39%), Positives = 129/240 (53%), Gaps = 20/240 (8%)
Query: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIY 131
D C S+ C + C G C+C PG+ G CE + G CQHG CHQ
Sbjct: 27 DDCSSH-CDLAHGCCAPDGS----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQPW-- 75
Query: 132 PVCICPAGYAGRFCEIDHDECAS-SPCQNGAVCQ-DGIDGYSCFCVPGYQGRHCDLEVDE 189
CIC +G+AG+FC+ D C + SPCQNG C DG Y C C+PG+ GR C+ +
Sbjct: 76 -QCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGP 134
Query: 190 C--ASDPCKNEATCLNEIG---RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALG 244
C A PC+N C ++ G +TC C + G CE+ +D+C +PC NGATC D +
Sbjct: 135 CEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGIN 194
Query: 245 AYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPL 304
+ C C GF G C +N D+CAS+PC G C D + + C C SG+ G CE ++P+
Sbjct: 195 RFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCP-SGYGGKTCELVLPV 253
Score = 153 bits (387), Expect = 1e-36
Identities = 80/215 (37%), Positives = 107/215 (49%), Gaps = 17/215 (7%)
Query: 134 CICPAGYAGRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
C C G+ G CE C P CQ+G Q + C C G+ G+ CD + C +
Sbjct: 46 CRCDPGWEGLHCE----RCVRMPGCQHGTCHQP----WQCICHSGWAGKFCDKDEHICTT 97
Query: 193 D-PCKNEATCLNEIG-RYTCICPHNYSGVNCELEIDECWS--QPCLNGATCQDALGA--- 245
PC+N C+ + G Y C+C + G +CE + C PC NG CQD G
Sbjct: 98 QSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN 157
Query: 246 YFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
+ C C GF+G CE+N D+C +PC +G C+DG NR+SC C GF G C + C
Sbjct: 158 FTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCP-EGFAGRFCTINLDDC 216
Query: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDL 340
S+PC A C D V ++ C C GY G CE+ L
Sbjct: 217 ASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251
Score = 144 bits (364), Expect = 5e-34
Identities = 90/276 (32%), Positives = 124/276 (44%), Gaps = 45/276 (16%)
Query: 130 IYPVCI-CPAGYAGRFCEIDHDECASSPCQ--NGAVCQDGIDGYSCFCVPGYQGRHCDLE 186
++ VC+ C G G+ + D+C SS C +G DG SC C PG++G HC+
Sbjct: 8 LHLVCLLCILGAPGQ--PVRADDC-SSHCDLAHGCCAPDG----SCRCDPGWEGLHCE-- 58
Query: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQ-PCLNGATCQ-DALG 244
C P TC + CIC ++G C+ + C +Q PC NG C D G
Sbjct: 59 --RCVRMPGCQHGTCHQP---WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGG 113
Query: 245 AYFCDCAPGFLGDHCELNTDEC--ASQPCLHGGLCVDGEN---RYSCNCTGSGFTGTHCE 299
Y C C PGF G CE C A PC +GG C D + ++C C GF G CE
Sbjct: 114 EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCL-VGFVGARCE 172
Query: 300 TLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSS 359
+ C +PC N ATC D ++ ++C C G+ G C I+L++C S PCQ C +
Sbjct: 173 VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRD--- 229
Query: 360 EKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE 395
+ C+C G+ G CE
Sbjct: 230 -----------------RVHDFDCLCPSGYGGKTCE 248
Score = 137 bits (346), Expect = 6e-32
Identities = 63/165 (38%), Positives = 90/165 (54%), Gaps = 7/165 (4%)
Query: 65 KDCDNMKDPCFS-NPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGK--NSCQH 121
K CD + C + +PCQ C+ G + C C PG+ G CE G C + + C++
Sbjct: 86 KFCDKDEHICTTQSPCQNGGQCMYDGGGE-YHCVCLPGFHGRDCERKAGPCEQAGSPCRN 144
Query: 122 GGICHQDPIYPV---CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGY 178
GG C D + + C C G+ G CE++ D+C PC NGA C DGI+ +SC C G+
Sbjct: 145 GGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGF 204
Query: 179 QGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCEL 223
GR C + +D+CAS PC+ A C + + + C+CP Y G CEL
Sbjct: 205 AGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 128 bits (321), Expect = 4e-29
Identities = 72/202 (35%), Positives = 91/202 (45%), Gaps = 21/202 (10%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCT 1201
C+S+ L G C S C C GW G HCE C P C HG C + C
Sbjct: 29 CSSHCDLAHGCCAPDGS---CRCDPGWEGLHCE----RCVRMPGCQHGTCHQ---PWQCI 78
Query: 1202 CEPGYTGVNCEVDIDNCQSHQ-CANGATCISHTNG-YSCLCFGNFTGKFCRQSRLPSTVC 1259
C G+ G C+ D C + C NG C+ G Y C+C F G+ C + P
Sbjct: 79 CHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPC--- 135
Query: 1260 GNEKTNLTCYNGGNCTE---FQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
E+ C NGG C + F C C GF G CE ++D+C PC NG C D +
Sbjct: 136 --EQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 1317 NKFQCLCDVAFAGERCEVDLAD 1338
N+F CLC FAG C ++L D
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDD 215
Score = 127 bits (320), Expect = 6e-29
Identities = 76/239 (31%), Positives = 101/239 (42%), Gaps = 39/239 (16%)
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
C C PG+ G HCE C P G C + C C SG+ G C+ +C +
Sbjct: 46 CRCDPGWEGLHCE----RCVRMPGCQHGTC---HQPWQCICH-SGWAGKFCDKDEHICTT 97
Query: 308 K-PCHNNATCE-DSVDNYTCHCWPGYTGAQCEIDLNECNS--NPCQSNGECVELSSEKQY 363
+ PC N C D Y C C PG+ G CE C +PC++ G+C +
Sbjct: 98 QSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQD------- 150
Query: 364 GRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
A + C C GF G CE +V++C PC NG TC + ++C C
Sbjct: 151 ----------DQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLC 200
Query: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
P + GR C+ L C + C C +D H F CLCPSGY G CE+
Sbjct: 201 P------EGFAGRFCTINLDDCASRPCQRGARC----RDRVHDFDCLCPSGYGGKTCEL 249
Score = 117 bits (293), Expect = 8e-26
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 19/223 (8%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFS-NPCIHGN--CSDRVAAYH 1199
C P G C + + C C GW+GK C+ + C + +PC +G D YH
Sbjct: 60 CVRMPGCQHGTC---HQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYH 116
Query: 1200 CTCEPGYTGVNCEVDIDNCQS--HQCANGATCISHTN---GYSCLCFGNFTGKFCRQSRL 1254
C C PG+ G +CE C+ C NG C ++C C F G C
Sbjct: 117 CVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE---- 172
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
V ++ C NG C + C+C GF G +C ++D+CAS PC G C+D
Sbjct: 173 ---VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRD 229
Query: 1315 LLNKFQCLCDVAFAGERCEVDL-ADDLISDIFTTIGSVTVALL 1356
++ F CLC + G+ CE+ L D + + T +G + ++
Sbjct: 230 RVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVV 272
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/102 (32%), Positives = 42/102 (41%), Gaps = 6/102 (5%)
Query: 12 FYLSFSL--LIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDN 69
F L+F+ L+ + C N CL C N +TC D C C + + C
Sbjct: 154 FALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPE--GFAGRFCTI 211
Query: 70 MKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTI 111
D C S PCQ A C + F C CP GY G CE +
Sbjct: 212 NLDDCASRPCQRGARCRDR--VHDFDCLCPSGYGGKTCELVL 251
Score = 52.8 bits (125), Expect = 2e-06
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C PC NG C + FSC CP +G+ C + C PC GA+C+ + F+
Sbjct: 176 DDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFD 235
Query: 948 CIANAVFNGQSGQIL 962
C+ + + G++ +++
Sbjct: 236 CLCPSGYGGKTCELV 250
Score = 44.3 bits (103), Expect = 8e-04
Identities = 17/39 (43%), Positives = 21/39 (53%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL 1176
+ L+ C S PC G C D + C CP G+ GK CEL
Sbjct: 211 INLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 886 AGDNSCKSNPCHNGGVCHSRWD---DFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQP 941
AG +PC NGG C +F+C C G CE V C PC +GA C
Sbjct: 132 AGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLD 191
Query: 942 VLQGFECIANAVFNGQ 957
+ F C+ F G+
Sbjct: 192 GINRFSCLCPEGFAGR 207
Score = 37.7 bits (86), Expect = 0.078
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 885 CAGDNSCKSNPCHNG--------------GVCHSRWDDFSCSCPALTSGKACEEVQ--WC 928
CA D SC+ +P G G CH W C C + +GK C++ +
Sbjct: 40 CAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPW---QCICHSGWAGKFCDKDEHICT 96
Query: 929 GFSPCPHGAQCQPVLQG-FECIANAVFNGQ 957
SPC +G QC G + C+ F+G+
Sbjct: 97 TQSPCQNGGQCMYDGGGEYHCVCLPGFHGR 126
Score = 31.2 bits (69), Expect = 7.3
Identities = 13/37 (35%), Positives = 17/37 (45%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ D C S+PCQ RC + + C C Y G C
Sbjct: 211 INLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 247
>gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 184 bits (468), Expect = 4e-46
Identities = 95/240 (39%), Positives = 129/240 (53%), Gaps = 20/240 (8%)
Query: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIY 131
D C S+ C + C G C+C PG+ G CE + G CQHG CHQ
Sbjct: 27 DDCSSH-CDLAHGCCAPDGS----CRCDPGWEGLHCERCVRMPG---CQHG-TCHQPW-- 75
Query: 132 PVCICPAGYAGRFCEIDHDECAS-SPCQNGAVCQ-DGIDGYSCFCVPGYQGRHCDLEVDE 189
CIC +G+AG+FC+ D C + SPCQNG C DG Y C C+PG+ GR C+ +
Sbjct: 76 -QCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGP 134
Query: 190 C--ASDPCKNEATCLNEIG---RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALG 244
C A PC+N C ++ G +TC C + G CE+ +D+C +PC NGATC D +
Sbjct: 135 CEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGIN 194
Query: 245 AYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPL 304
+ C C GF G C +N D+CAS+PC G C D + + C C SG+ G CE ++P+
Sbjct: 195 RFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCP-SGYGGKTCELVLPV 253
Score = 153 bits (387), Expect = 1e-36
Identities = 80/215 (37%), Positives = 107/215 (49%), Gaps = 17/215 (7%)
Query: 134 CICPAGYAGRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
C C G+ G CE C P CQ+G Q + C C G+ G+ CD + C +
Sbjct: 46 CRCDPGWEGLHCE----RCVRMPGCQHGTCHQP----WQCICHSGWAGKFCDKDEHICTT 97
Query: 193 D-PCKNEATCLNEIG-RYTCICPHNYSGVNCELEIDECWS--QPCLNGATCQDALGA--- 245
PC+N C+ + G Y C+C + G +CE + C PC NG CQD G
Sbjct: 98 QSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALN 157
Query: 246 YFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
+ C C GF+G CE+N D+C +PC +G C+DG NR+SC C GF G C + C
Sbjct: 158 FTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCP-EGFAGRFCTINLDDC 216
Query: 306 WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDL 340
S+PC A C D V ++ C C GY G CE+ L
Sbjct: 217 ASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251
Score = 144 bits (364), Expect = 5e-34
Identities = 90/276 (32%), Positives = 124/276 (44%), Gaps = 45/276 (16%)
Query: 130 IYPVCI-CPAGYAGRFCEIDHDECASSPCQ--NGAVCQDGIDGYSCFCVPGYQGRHCDLE 186
++ VC+ C G G+ + D+C SS C +G DG SC C PG++G HC+
Sbjct: 8 LHLVCLLCILGAPGQ--PVRADDC-SSHCDLAHGCCAPDG----SCRCDPGWEGLHCE-- 58
Query: 187 VDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQ-PCLNGATCQ-DALG 244
C P TC + CIC ++G C+ + C +Q PC NG C D G
Sbjct: 59 --RCVRMPGCQHGTCHQP---WQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGG 113
Query: 245 AYFCDCAPGFLGDHCELNTDEC--ASQPCLHGGLCVDGEN---RYSCNCTGSGFTGTHCE 299
Y C C PGF G CE C A PC +GG C D + ++C C GF G CE
Sbjct: 114 EYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCL-VGFVGARCE 172
Query: 300 TLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSS 359
+ C +PC N ATC D ++ ++C C G+ G C I+L++C S PCQ C +
Sbjct: 173 VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRD--- 229
Query: 360 EKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCE 395
+ C+C G+ G CE
Sbjct: 230 -----------------RVHDFDCLCPSGYGGKTCE 248
Score = 137 bits (346), Expect = 6e-32
Identities = 63/165 (38%), Positives = 90/165 (54%), Gaps = 7/165 (4%)
Query: 65 KDCDNMKDPCFS-NPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGK--NSCQH 121
K CD + C + +PCQ C+ G + C C PG+ G CE G C + + C++
Sbjct: 86 KFCDKDEHICTTQSPCQNGGQCMYDGGGE-YHCVCLPGFHGRDCERKAGPCEQAGSPCRN 144
Query: 122 GGICHQDPIYPV---CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGY 178
GG C D + + C C G+ G CE++ D+C PC NGA C DGI+ +SC C G+
Sbjct: 145 GGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGF 204
Query: 179 QGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCEL 223
GR C + +D+CAS PC+ A C + + + C+CP Y G CEL
Sbjct: 205 AGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 128 bits (321), Expect = 4e-29
Identities = 72/202 (35%), Positives = 91/202 (45%), Gaps = 21/202 (10%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-CIHGNCSDRVAAYHCT 1201
C+S+ L G C S C C GW G HCE C P C HG C + C
Sbjct: 29 CSSHCDLAHGCCAPDGS---CRCDPGWEGLHCE----RCVRMPGCQHGTCHQ---PWQCI 78
Query: 1202 CEPGYTGVNCEVDIDNCQSHQ-CANGATCISHTNG-YSCLCFGNFTGKFCRQSRLPSTVC 1259
C G+ G C+ D C + C NG C+ G Y C+C F G+ C + P
Sbjct: 79 CHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPC--- 135
Query: 1260 GNEKTNLTCYNGGNCTE---FQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
E+ C NGG C + F C C GF G CE ++D+C PC NG C D +
Sbjct: 136 --EQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGI 193
Query: 1317 NKFQCLCDVAFAGERCEVDLAD 1338
N+F CLC FAG C ++L D
Sbjct: 194 NRFSCLCPEGFAGRFCTINLDD 215
Score = 127 bits (320), Expect = 6e-29
Identities = 76/239 (31%), Positives = 101/239 (42%), Gaps = 39/239 (16%)
Query: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
C C PG+ G HCE C P G C + C C SG+ G C+ +C +
Sbjct: 46 CRCDPGWEGLHCE----RCVRMPGCQHGTC---HQPWQCICH-SGWAGKFCDKDEHICTT 97
Query: 308 K-PCHNNATCE-DSVDNYTCHCWPGYTGAQCEIDLNECNS--NPCQSNGECVELSSEKQY 363
+ PC N C D Y C C PG+ G CE C +PC++ G+C +
Sbjct: 98 QSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQD------- 150
Query: 364 GRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
A + C C GF G CE +V++C PC NG TC + ++C C
Sbjct: 151 ----------DQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLC 200
Query: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
P + GR C+ L C + C C +D H F CLCPSGY G CE+
Sbjct: 201 P------EGFAGRFCTINLDDCASRPCQRGARC----RDRVHDFDCLCPSGYGGKTCEL 249
Score = 117 bits (293), Expect = 8e-26
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 19/223 (8%)
Query: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFS-NPCIHGN--CSDRVAAYH 1199
C P G C + + C C GW+GK C+ + C + +PC +G D YH
Sbjct: 60 CVRMPGCQHGTC---HQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYH 116
Query: 1200 CTCEPGYTGVNCEVDIDNCQS--HQCANGATCISHTN---GYSCLCFGNFTGKFCRQSRL 1254
C C PG+ G +CE C+ C NG C ++C C F G C
Sbjct: 117 CVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCE---- 172
Query: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
V ++ C NG C + C+C GF G +C ++D+CAS PC G C+D
Sbjct: 173 ---VNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRD 229
Query: 1315 LLNKFQCLCDVAFAGERCEVDL-ADDLISDIFTTIGSVTVALL 1356
++ F CLC + G+ CE+ L D + + T +G + ++
Sbjct: 230 RVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVV 272
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/102 (32%), Positives = 42/102 (41%), Gaps = 6/102 (5%)
Query: 12 FYLSFSL--LIYIKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDN 69
F L+F+ L+ + C N CL C N +TC D C C + + C
Sbjct: 154 FALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPE--GFAGRFCTI 211
Query: 70 MKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTI 111
D C S PCQ A C + F C CP GY G CE +
Sbjct: 212 NLDDCASRPCQRGARCRDR--VHDFDCLCPSGYGGKTCELVL 251
Score = 52.8 bits (125), Expect = 2e-06
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
+ C PC NG C + FSC CP +G+ C + C PC GA+C+ + F+
Sbjct: 176 DDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFD 235
Query: 948 CIANAVFNGQSGQIL 962
C+ + + G++ +++
Sbjct: 236 CLCPSGYGGKTCELV 250
Score = 44.3 bits (103), Expect = 8e-04
Identities = 17/39 (43%), Positives = 21/39 (53%)
Query: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL 1176
+ L+ C S PC G C D + C CP G+ GK CEL
Sbjct: 211 INLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCEL 249
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 886 AGDNSCKSNPCHNGGVCHSRWD---DFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQP 941
AG +PC NGG C +F+C C G CE V C PC +GA C
Sbjct: 132 AGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLD 191
Query: 942 VLQGFECIANAVFNGQ 957
+ F C+ F G+
Sbjct: 192 GINRFSCLCPEGFAGR 207
Score = 37.7 bits (86), Expect = 0.078
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 885 CAGDNSCKSNPCHNG--------------GVCHSRWDDFSCSCPALTSGKACEEVQ--WC 928
CA D SC+ +P G G CH W C C + +GK C++ +
Sbjct: 40 CAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPW---QCICHSGWAGKFCDKDEHICT 96
Query: 929 GFSPCPHGAQCQPVLQG-FECIANAVFNGQ 957
SPC +G QC G + C+ F+G+
Sbjct: 97 TQSPCQNGGQCMYDGGGEYHCVCLPGFHGR 126
Score = 31.2 bits (69), Expect = 7.3
Identities = 13/37 (35%), Positives = 17/37 (45%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
+ D C S+PCQ RC + + C C Y G C
Sbjct: 211 INLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 247
>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
Length = 618
Score = 173 bits (438), Expect = 1e-42
Identities = 89/263 (33%), Positives = 122/263 (46%), Gaps = 30/263 (11%)
Query: 65 KDCDNMKDPCFSNPCQGSATCVNTPG--ERSFLCKCPPGYSGTICETTI----------- 111
+ C ++D C + P A C G E+ C+C G++G +C +
Sbjct: 205 RPCAPLEDECEA-PLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGP 263
Query: 112 ------------GSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQN 159
G C N C +GG C + P C CP G+ G CE+ CA PC N
Sbjct: 264 SSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFN 323
Query: 160 GAVCQDGID---GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216
G +C G D Y C C PG+QG +C+ VD C+ PC+N CL+ C C +
Sbjct: 324 GGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGF 383
Query: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL 276
+G CE ++D+C + C NG TC + GA+ C CA GF G C D CA++PC HGG
Sbjct: 384 AGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGR 443
Query: 277 CVDGENRYSCNCTGSGFTGTHCE 299
C + C C G+ G CE
Sbjct: 444 CYAHFSGLVCAC-APGYMGARCE 465
Score = 156 bits (395), Expect = 1e-37
Identities = 96/319 (30%), Positives = 125/319 (39%), Gaps = 34/319 (10%)
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVC----ICPAGYAGR--FCE 146
S+ +C P GT C S G+ P+ C +C AG + FCE
Sbjct: 173 SYRARCEPPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCE 232
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD---ECASDPCKNEATCLN 203
EC G +C + SC G V C +PC N +C
Sbjct: 233 -QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSE 291
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC---QDALGAYFCDCAPGFLGDHCE 260
+ C CP + G+ CE+ C PC NG C D AY C C PGF G +CE
Sbjct: 292 TPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCE 351
Query: 261 LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
D C+ QPC +GGLC+D + C C +GF G CE + C + C N TC +
Sbjct: 352 KRVDRCSLQPCRNGGLCLDLGHALRCRCR-AGFAGPRCEHDLDDCAGRACANGGTCVEGG 410
Query: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
+ C C G+ G C + C + PC G C Y SG
Sbjct: 411 GAHRCSCALGFGGRDCRERADPCAARPCAHGGRC--------------------YAHFSG 450
Query: 381 YVCICQPGFTGIHCEEDVN 399
VC C PG+ G CE V+
Sbjct: 451 LVCACAPGYMGARCEFPVH 469
Score = 150 bits (378), Expect = 1e-35
Identities = 81/251 (32%), Positives = 112/251 (44%), Gaps = 32/251 (12%)
Query: 1114 HGFINKPQEEQFLK----------ISTNSVV---------TGCLQLNV--CNSNPCLHGG 1152
HGF +P E + L+ +ST+S + TGCL C+ NPC +GG
Sbjct: 228 HGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGG 287
Query: 1153 NCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNC----SDRVAAYHCTCEPGYTG 1208
+C + S+ C+CP G+ G CE++ C PC +G +D +AY C C PG+ G
Sbjct: 288 SCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQG 347
Query: 1209 VNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTC 1268
NCE +D C C NG C+ + C C F G C ++ C
Sbjct: 348 SNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-------DDCAGRAC 400
Query: 1269 YNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFA 1328
NGG C E +C C GF G C + D CA+ PC +GG C + C C +
Sbjct: 401 ANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYM 460
Query: 1329 GERCEVDLADD 1339
G RCE + D
Sbjct: 461 GARCEFPVHPD 471
Score = 146 bits (368), Expect = 2e-34
Identities = 93/329 (28%), Positives = 126/329 (38%), Gaps = 47/329 (14%)
Query: 161 AVCQDGIDGYSC--FCVPGYQGRHCDLEVDECA--SDPCKNEATCLNEIGRYTCICPHNY 216
A C+ G +C C P C + CA D C+ C R C H +
Sbjct: 176 ARCEPPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVC-----RAGCSPEHGF 230
Query: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL-NTDECASQPCLHGG 275
E E W+ P T + + P C + C PC +GG
Sbjct: 231 CEQPGECRCLEGWTGPL---CTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGG 287
Query: 276 LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN---YTCHCWPGYT 332
C + + C C GF G CE C PC N C D Y CHC PG+
Sbjct: 288 SCSETPRSFECTCP-RGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQ 346
Query: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGI 392
G+ CE ++ C+ PC++ G C++L + C C+ GF G
Sbjct: 347 GSNCEKRVDRCSLQPCRNGGLCLDLGHALR--------------------CRCRAGFAGP 386
Query: 393 HCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLN 452
CE D+++C+ C NGGTC G + C C +GGRDC + C + C +
Sbjct: 387 RCEHDLDDCAGRACANGGTCVEGGGAHRCSCALG------FGGRDCRERADPCAARPCAH 440
Query: 453 NGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
G C HF G C C GY G+ CE
Sbjct: 441 GGRCYAHFS----GLVCACAPGYMGARCE 465
Score = 135 bits (339), Expect = 4e-31
Identities = 62/193 (32%), Positives = 86/193 (44%), Gaps = 3/193 (1%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVN-TPGER 92
C N C N +C + + +C+C L C+ C PC CV +
Sbjct: 278 CDGNPCANGGSCSETPRSFECTCPRGFYGLR--CEVSGVTCADGPCFNGGLCVGGADPDS 335
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDEC 152
+++C CPPG+ G+ CE + C C++GG+C C C AG+AG CE D D+C
Sbjct: 336 AYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDC 395
Query: 153 ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCIC 212
A C NG C +G + C C G+ GR C D CA+ PC + C C C
Sbjct: 396 AGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCAC 455
Query: 213 PHNYSGVNCELEI 225
Y G CE +
Sbjct: 456 APGYMGARCEFPV 468
Score = 120 bits (300), Expect = 1e-26
Identities = 62/175 (35%), Positives = 81/175 (46%), Gaps = 13/175 (7%)
Query: 1143 CNSNPCLHGGNC---EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
C PC +GG C D S+Y C CP G+ G +CE +D C PC +G C D A
Sbjct: 316 CADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHAL 375
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C G+ G CE D+D+C CANG TC+ + C C F G+ CR+ P
Sbjct: 376 RCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAA 435
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI--DECASDPCVNGGL 1311
C +GG C + L C C PG+ G CE + D ++ P GL
Sbjct: 436 -------RPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGL 483
Score = 114 bits (284), Expect = 9e-25
Identities = 66/219 (30%), Positives = 90/219 (41%), Gaps = 39/219 (17%)
Query: 1142 VCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDE--------------------- 1180
VC + G CE C C GW+G C + +
Sbjct: 219 VCRAGCSPEHGFCEQ---PGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGP 275
Query: 1181 --CFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN--- 1234
C NPC +G +CS+ ++ CTC G+ G+ CEV C C NG C+ +
Sbjct: 276 GPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDS 335
Query: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLT-CYNGGNCTEFQTELKCMCRPGFTGEW 1293
Y C C F G C + ++ +L C NGG C + L+C CR GF G
Sbjct: 336 AYICHCPPGFQGSNCEKRV--------DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPR 387
Query: 1294 CEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
CE D+D+CA C NGG C + +C C + F G C
Sbjct: 388 CEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDC 426
Score = 73.2 bits (178), Expect = 2e-12
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 5/134 (3%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ S C K RC C+N C D C C A C++ D C C
Sbjct: 346 QGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRC--RAGFAGPRCEHDLDDCAGRACANG 403
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
TCV G + C C G+ G C C C HGG C+ VC C GY G
Sbjct: 404 GTCVE--GGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMG 461
Query: 143 RFCEID-HDECASS 155
CE H + AS+
Sbjct: 462 ARCEFPVHPDGASA 475
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/63 (38%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Query: 880 NVTQGCA--GDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHG 936
+ T GC G C NPC NGG C F C+CP G CE C PC +G
Sbjct: 265 SATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNG 324
Query: 937 AQC 939
C
Sbjct: 325 GLC 327
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/61 (32%), Positives = 23/61 (37%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
+ C C NGG C CSC G+ C E C PC HG +C G
Sbjct: 393 DDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLV 452
Query: 948 C 948
C
Sbjct: 453 C 453
Score = 38.1 bits (87), Expect = 0.060
Identities = 14/36 (38%), Positives = 21/36 (58%)
Query: 672 RKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
R D C QPC++ G C++L + +C C + GP C
Sbjct: 353 RVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRC 388
Score = 38.1 bits (87), Expect = 0.060
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 1/68 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
C PC NGG+C C C A +G CE ++ C C +G C C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 950 ANAVFNGQ 957
F G+
Sbjct: 417 CALGFGGR 424
Score = 35.4 bits (80), Expect = 0.39
Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 12/96 (12%)
Query: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCT--------HQQCLNNGTCI 457
C+ G C L G C + + R S GC C N G+C
Sbjct: 231 CEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSC- 289
Query: 458 PHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGF 493
+ F C CP G+ G CE++ +G F
Sbjct: 290 ---SETPRSFECTCPRGFYGLRCEVSGVTCADGPCF 322
Score = 33.5 bits (75), Expect = 1.5
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 6/51 (11%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQP 941
C + PC +GG C++ + C+C G CE F P GA P
Sbjct: 433 CAARPCAHGGRCYAHFSGLVCACAPGYMGARCE------FPVHPDGASALP 477
Score = 31.6 bits (70), Expect = 5.6
Identities = 11/32 (34%), Positives = 16/32 (50%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C+ PC + G C S++C C R + G C
Sbjct: 278 CDGNPCANGGSCSETPRSFECTCPRGFYGLRC 309
>gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens]
Length = 587
Score = 173 bits (438), Expect = 1e-42
Identities = 89/263 (33%), Positives = 122/263 (46%), Gaps = 30/263 (11%)
Query: 65 KDCDNMKDPCFSNPCQGSATCVNTPG--ERSFLCKCPPGYSGTICETTI----------- 111
+ C ++D C + P A C G E+ C+C G++G +C +
Sbjct: 205 RPCAPLEDECEA-PLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGP 263
Query: 112 ------------GSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQN 159
G C N C +GG C + P C CP G+ G CE+ CA PC N
Sbjct: 264 SSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFN 323
Query: 160 GAVCQDGID---GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNY 216
G +C G D Y C C PG+QG +C+ VD C+ PC+N CL+ C C +
Sbjct: 324 GGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGF 383
Query: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL 276
+G CE ++D+C + C NG TC + GA+ C CA GF G C D CA++PC HGG
Sbjct: 384 AGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGR 443
Query: 277 CVDGENRYSCNCTGSGFTGTHCE 299
C + C C G+ G CE
Sbjct: 444 CYAHFSGLVCAC-APGYMGARCE 465
Score = 156 bits (395), Expect = 1e-37
Identities = 96/319 (30%), Positives = 125/319 (39%), Gaps = 34/319 (10%)
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVC----ICPAGYAGR--FCE 146
S+ +C P GT C S G+ P+ C +C AG + FCE
Sbjct: 173 SYRARCEPPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCE 232
Query: 147 IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD---ECASDPCKNEATCLN 203
EC G +C + SC G V C +PC N +C
Sbjct: 233 -QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSE 291
Query: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATC---QDALGAYFCDCAPGFLGDHCE 260
+ C CP + G+ CE+ C PC NG C D AY C C PGF G +CE
Sbjct: 292 TPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCE 351
Query: 261 LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
D C+ QPC +GGLC+D + C C +GF G CE + C + C N TC +
Sbjct: 352 KRVDRCSLQPCRNGGLCLDLGHALRCRCR-AGFAGPRCEHDLDDCAGRACANGGTCVEGG 410
Query: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
+ C C G+ G C + C + PC G C Y SG
Sbjct: 411 GAHRCSCALGFGGRDCRERADPCAARPCAHGGRC--------------------YAHFSG 450
Query: 381 YVCICQPGFTGIHCEEDVN 399
VC C PG+ G CE V+
Sbjct: 451 LVCACAPGYMGARCEFPVH 469
Score = 150 bits (378), Expect = 1e-35
Identities = 81/251 (32%), Positives = 112/251 (44%), Gaps = 32/251 (12%)
Query: 1114 HGFINKPQEEQFLK----------ISTNSVV---------TGCLQLNV--CNSNPCLHGG 1152
HGF +P E + L+ +ST+S + TGCL C+ NPC +GG
Sbjct: 228 HGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGG 287
Query: 1153 NCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNC----SDRVAAYHCTCEPGYTG 1208
+C + S+ C+CP G+ G CE++ C PC +G +D +AY C C PG+ G
Sbjct: 288 SCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQG 347
Query: 1209 VNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTC 1268
NCE +D C C NG C+ + C C F G C ++ C
Sbjct: 348 SNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-------DDCAGRAC 400
Query: 1269 YNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFA 1328
NGG C E +C C GF G C + D CA+ PC +GG C + C C +
Sbjct: 401 ANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYM 460
Query: 1329 GERCEVDLADD 1339
G RCE + D
Sbjct: 461 GARCEFPVHPD 471
Score = 146 bits (368), Expect = 2e-34
Identities = 93/329 (28%), Positives = 126/329 (38%), Gaps = 47/329 (14%)
Query: 161 AVCQDGIDGYSC--FCVPGYQGRHCDLEVDECA--SDPCKNEATCLNEIGRYTCICPHNY 216
A C+ G +C C P C + CA D C+ C R C H +
Sbjct: 176 ARCEPPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVC-----RAGCSPEHGF 230
Query: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL-NTDECASQPCLHGG 275
E E W+ P T + + P C + C PC +GG
Sbjct: 231 CEQPGECRCLEGWTGPL---CTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGG 287
Query: 276 LCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN---YTCHCWPGYT 332
C + + C C GF G CE C PC N C D Y CHC PG+
Sbjct: 288 SCSETPRSFECTCP-RGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQ 346
Query: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGI 392
G+ CE ++ C+ PC++ G C++L + C C+ GF G
Sbjct: 347 GSNCEKRVDRCSLQPCRNGGLCLDLGHALR--------------------CRCRAGFAGP 386
Query: 393 HCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLN 452
CE D+++C+ C NGGTC G + C C +GGRDC + C + C +
Sbjct: 387 RCEHDLDDCAGRACANGGTCVEGGGAHRCSCALG------FGGRDCRERADPCAARPCAH 440
Query: 453 NGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
G C HF G C C GY G+ CE
Sbjct: 441 GGRCYAHFS----GLVCACAPGYMGARCE 465
Score = 135 bits (339), Expect = 4e-31
Identities = 62/193 (32%), Positives = 86/193 (44%), Gaps = 3/193 (1%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVN-TPGER 92
C N C N +C + + +C+C L C+ C PC CV +
Sbjct: 278 CDGNPCANGGSCSETPRSFECTCPRGFYGLR--CEVSGVTCADGPCFNGGLCVGGADPDS 335
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDEC 152
+++C CPPG+ G+ CE + C C++GG+C C C AG+AG CE D D+C
Sbjct: 336 AYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDC 395
Query: 153 ASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCIC 212
A C NG C +G + C C G+ GR C D CA+ PC + C C C
Sbjct: 396 AGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCAC 455
Query: 213 PHNYSGVNCELEI 225
Y G CE +
Sbjct: 456 APGYMGARCEFPV 468
Score = 120 bits (300), Expect = 1e-26
Identities = 62/175 (35%), Positives = 81/175 (46%), Gaps = 13/175 (7%)
Query: 1143 CNSNPCLHGGNC---EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
C PC +GG C D S+Y C CP G+ G +CE +D C PC +G C D A
Sbjct: 316 CADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHAL 375
Query: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
C C G+ G CE D+D+C CANG TC+ + C C F G+ CR+ P
Sbjct: 376 RCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAA 435
Query: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI--DECASDPCVNGGL 1311
C +GG C + L C C PG+ G CE + D ++ P GL
Sbjct: 436 -------RPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGL 483
Score = 114 bits (284), Expect = 9e-25
Identities = 66/219 (30%), Positives = 90/219 (41%), Gaps = 39/219 (17%)
Query: 1142 VCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDE--------------------- 1180
VC + G CE C C GW+G C + +
Sbjct: 219 VCRAGCSPEHGFCEQ---PGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGP 275
Query: 1181 --CFSNPCIHG-NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN--- 1234
C NPC +G +CS+ ++ CTC G+ G+ CEV C C NG C+ +
Sbjct: 276 GPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDS 335
Query: 1235 GYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLT-CYNGGNCTEFQTELKCMCRPGFTGEW 1293
Y C C F G C + ++ +L C NGG C + L+C CR GF G
Sbjct: 336 AYICHCPPGFQGSNCEKRV--------DRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPR 387
Query: 1294 CEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
CE D+D+CA C NGG C + +C C + F G C
Sbjct: 388 CEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDC 426
Score = 73.2 bits (178), Expect = 2e-12
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 5/134 (3%)
Query: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
+ S C K RC C+N C D C C A C++ D C C
Sbjct: 346 QGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRC--RAGFAGPRCEHDLDDCAGRACANG 403
Query: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
TCV G + C C G+ G C C C HGG C+ VC C GY G
Sbjct: 404 GTCVE--GGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMG 461
Query: 143 RFCEID-HDECASS 155
CE H + AS+
Sbjct: 462 ARCEFPVHPDGASA 475
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/63 (38%), Positives = 27/63 (42%), Gaps = 3/63 (4%)
Query: 880 NVTQGCA--GDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHG 936
+ T GC G C NPC NGG C F C+CP G CE C PC +G
Sbjct: 265 SATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNG 324
Query: 937 AQC 939
C
Sbjct: 325 GLC 327
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/61 (32%), Positives = 23/61 (37%), Gaps = 1/61 (1%)
Query: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
+ C C NGG C CSC G+ C E C PC HG +C G
Sbjct: 393 DDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLV 452
Query: 948 C 948
C
Sbjct: 453 C 453
Score = 38.1 bits (87), Expect = 0.060
Identities = 14/36 (38%), Positives = 21/36 (58%)
Query: 672 RKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
R D C QPC++ G C++L + +C C + GP C
Sbjct: 353 RVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRC 388
Score = 38.1 bits (87), Expect = 0.060
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 1/68 (1%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECI 949
C PC NGG+C C C A +G CE ++ C C +G C C
Sbjct: 357 CSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCS 416
Query: 950 ANAVFNGQ 957
F G+
Sbjct: 417 CALGFGGR 424
Score = 35.4 bits (80), Expect = 0.39
Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 12/96 (12%)
Query: 406 CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCT--------HQQCLNNGTCI 457
C+ G C L G C + + R S GC C N G+C
Sbjct: 231 CEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSC- 289
Query: 458 PHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGF 493
+ F C CP G+ G CE++ +G F
Sbjct: 290 ---SETPRSFECTCPRGFYGLRCEVSGVTCADGPCF 322
Score = 33.5 bits (75), Expect = 1.5
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 6/51 (11%)
Query: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQP 941
C + PC +GG C++ + C+C G CE F P GA P
Sbjct: 433 CAARPCAHGGRCYAHFSGLVCACAPGYMGARCE------FPVHPDGASALP 477
Score = 31.6 bits (70), Expect = 5.6
Identities = 11/32 (34%), Positives = 16/32 (50%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C+ PC + G C S++C C R + G C
Sbjct: 278 CDGNPCANGGSCSETPRSFECTCPRGFYGLRC 309
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 165 bits (418), Expect = 2e-40
Identities = 108/350 (30%), Positives = 157/350 (44%), Gaps = 67/350 (19%)
Query: 114 CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDEC---ASSP--CQNGAVCQDGID 168
C N CQ+GG C CICP + G C D +EC + +P CQNG C + +
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMG 195
Query: 169 GYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI-----------GRYTCICPHNY- 216
YSC C P G C + D+C + A C++ I +Y+C+C +
Sbjct: 196 SYSCHCPPETYGPQCASKYDDCEGG---SVARCVHGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 217 ---SGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAP-GFLGD--------HCELN 262
+ C L+ DEC QP C C + G+++C P G+ G+ CE+N
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN 312
Query: 263 TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGT-HCETLMPLCW--SKPCHNNATCEDS 319
C+ P + CV+ C G+ G TL +C + CH +A+C +
Sbjct: 313 NGGCSVAPPVE---CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSST 369
Query: 320 VDNYT-CHCWPGYTGAQ-----CEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSF 373
+ + C C PGYTG C N C S+PC NG+C++
Sbjct: 370 LGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCL-NGQCIDT---------------- 412
Query: 374 SYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC 423
SGY C C G+TG++C E++NEC SNPC NGGTC + +++C C
Sbjct: 413 ----VSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 153 bits (387), Expect = 1e-36
Identities = 113/357 (31%), Positives = 151/357 (42%), Gaps = 47/357 (13%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP---CQGSATCVNTPG 90
C SN CQN TC + C C D + +S CQ TCVNT G
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMG 195
Query: 91 ERSFLCKCPPGYSGTICETTIGSCGKNS---CQHGGICHQ-------DPIYPVCICPAGY 140
S+ C CPP G C + C S C HG IC +P Y C+C AG+
Sbjct: 196 --SYSCHCPPETYGPQCASKYDDCEGGSVARCVHG-ICEDLMREQAGEPKYS-CVCDAGW 251
Query: 141 A----GRFCEIDHDECA--SSPCQNGAVCQDGIDGYSC-FCVPGYQGR--------HCDL 185
C +D DEC+ PC C + + C C G+QG C++
Sbjct: 252 MFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEI 311
Query: 186 EVDECASDPCKNEATCLNEIGRYTC-ICPHNYSGVN--CEL-EIDECWSQPCLNGATCQD 241
C+ P C+N G C CP Y G C L +I + C A+C
Sbjct: 312 NNGGCSVAP---PVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSS 368
Query: 242 ALGAY-FCDCAPGFLGDH-----CELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTG 295
LG+ C C PG+ G+ C ++ C S PCL+G C+D + Y C C SG+TG
Sbjct: 369 TLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCD-SGWTG 426
Query: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNG 352
+C + C S PC N TC D VD+++C C +TGA C++ C + NG
Sbjct: 427 VNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGING 483
Score = 141 bits (355), Expect = 5e-33
Identities = 107/360 (29%), Positives = 153/360 (42%), Gaps = 69/360 (19%)
Query: 178 YQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDEC-----WSQP 232
+QG ++ C+S+PC+N TCLN + CICP + G C +++EC
Sbjct: 124 FQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS 183
Query: 233 CLNGATCQDALGAYFCDCAPGFLGDHCELNTDEC---ASQPCLHGGLCVD------GENR 283
C NG TC + +G+Y C C P G C D+C + C+H G+C D GE +
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH-GICEDLMREQAGEPK 242
Query: 284 YSCNCTGSGFTGTH---CETLMPLCWSK--PCHNNATCEDSVDNYTCHC----WPGYTGA 334
YSC C + C C + PC C ++ ++ C W G G
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQG-NGY 301
Query: 335 QCEIDLNEC--NSNPCQ--SNGECVELSSEKQY----------GRITGL----------- 369
CE D+NEC N+ C ECV GR+ L
Sbjct: 302 ICE-DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGC 360
Query: 370 --PSSFSYHEASGYVCICQPGFTG-----IHCEEDVNECSSNPCQNGGTCENLPGNYTCH 422
+S S S +C C PG+TG C + N C S+PC NG + + G Y C
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSG-YFCK 419
Query: 423 CPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
C + + G +C++ + C CLN GTC+ DG FSC C +TG+LC++
Sbjct: 420 CD------SGWTGVNCTENINECLSNPCLNGGTCV----DGVDSFSCECTRLWTGALCQV 469
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/207 (31%), Positives = 91/207 (43%), Gaps = 29/207 (14%)
Query: 1147 PCLHGGNCEDIYSSYHC-SCPLGWSGK--------HCELNIDECFSNPCIHGNCSDRVAA 1197
PC C + S++C +CP GW G CE+N C P + C + +
Sbjct: 273 PCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVE--CVNTPGS 330
Query: 1198 YHC-TCEPGYTG---VNCEVDIDNCQSHQCANGATCISHTNGYS-CLCFGNFTGKF---- 1248
HC C PGY G V DI + + C A+C S C C +TG
Sbjct: 331 SHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPN 390
Query: 1249 -CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCV 1307
C Q S +C + C NG C + + C C G+TG C ++I+EC S+PC+
Sbjct: 391 GCVQL---SNICLSHP----CLNG-QCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCL 442
Query: 1308 NGGLCQDLLNKFQCLCDVAFAGERCEV 1334
NGG C D ++ F C C + G C+V
Sbjct: 443 NGGTCVDGVDSFSCECTRLWTGALCQV 469
Score = 93.2 bits (230), Expect = 2e-18
Identities = 45/138 (32%), Positives = 71/138 (51%), Gaps = 11/138 (7%)
Query: 1137 CLQLNVCN--SNPCLHGGNCEDIYSSYH-CSCPLGWSGKH-----CELNIDECFSNPCIH 1188
C ++C+ + C +C S C+C G++G C + C S+PC++
Sbjct: 347 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLN 406
Query: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKF 1248
G C D V+ Y C C+ G+TGVNC +I+ C S+ C NG TC+ + +SC C +TG
Sbjct: 407 GQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCECTRLWTGAL 466
Query: 1249 CRQSRLPSTVCGNEKTNL 1266
C ++P VCG + +
Sbjct: 467 C---QVPQQVCGESLSGI 481
Score = 76.3 bits (186), Expect = 2e-13
Identities = 60/183 (32%), Positives = 78/183 (42%), Gaps = 29/183 (15%)
Query: 1137 CLQLNVCNSNPCLHGG-------NCEDIYSSYHC-SCPLGWSG--KHCELNIDECFSNPC 1186
C +N C N +GG C + S HC +CP G+ G + C L SN
Sbjct: 303 CEDINECEIN---NGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Query: 1187 IH--GNCSDRVAAYH-CTCEPGYTG----VNCEVDIDN-CQSHQCANGATCISHTNGYSC 1238
H +CS + + CTC PGYTG N V + N C SH C NG CI +GY C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFC 418
Query: 1239 LCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
C +TG C ++ NE + C NGG C + C C +TG C+
Sbjct: 419 KCDSGWTGVNCTENI-------NECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQ 471
Query: 1299 DEC 1301
C
Sbjct: 472 QVC 474
Score = 74.3 bits (181), Expect = 8e-13
Identities = 70/304 (23%), Positives = 103/304 (33%), Gaps = 106/304 (34%)
Query: 1142 VCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC--FSNP-------------- 1185
VC+SNPC +GG C +++ S+ C CP W G C +++EC +S
Sbjct: 135 VCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 1186 ------------------------------CIHGNCSDRVAA------YHCTCEPGY--- 1206
C+HG C D + Y C C+ G+
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFS 254
Query: 1207 -TGVNCEVDIDNC--QSHQCANGATCISHTNGYSC-LCFGNFTGK--FCRQ--------- 1251
C +D D C Q C+ C + + C C + G C
Sbjct: 255 PNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNG 314
Query: 1252 --SRLPSTVCGNEKTNLTCY----------------------NGG-----NCTEFQTELK 1282
S P C N + C NGG +C+ L
Sbjct: 315 GCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLP 374
Query: 1283 -CMCRPGFTGEW-----CEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
C C PG+TG C + + C S PC+NG C D ++ + C CD + G C ++
Sbjct: 375 LCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGWTGVNCTENI 433
Query: 1337 ADDL 1340
+ L
Sbjct: 434 NECL 437
Score = 73.6 bits (179), Expect = 1e-12
Identities = 69/270 (25%), Positives = 98/270 (36%), Gaps = 43/270 (15%)
Query: 243 LGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLM 302
L + D F G ++ C+S PC +GG C++ + + C C + G C +
Sbjct: 113 LNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQ-WKGPLCSADV 171
Query: 303 PLC-----WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL 357
C C N TC +++ +Y+CHC P G QC ++C S CV
Sbjct: 172 NECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGG---SVARCVHG 228
Query: 358 SSEKQYGRITGLPSSFSYHEASGYVCICQPGF----TGIHCEEDVNECS--SNPCQNGGT 411
E G P Y C+C G+ C D +ECS PC
Sbjct: 229 ICEDLMREQAGEPK---------YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQ 279
Query: 412 CENLPGNYTC-HCPFDNLSRTFYGGRDCSDILLGCTHQQC-LNNGTC-----IPHFQDGQ 464
C N G++ C CP + G C DI +C +NNG C +
Sbjct: 280 CFNTQGSFYCGACP----TGWQGNGYICEDI------NECEINNGGCSVAPPVECVNTPG 329
Query: 465 HGFSCLCPSGYTGS--LCEIATTLSFEGDG 492
CP GY G +C + S G
Sbjct: 330 SSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Score = 71.2 bits (173), Expect = 6e-12
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 12/134 (8%)
Query: 1203 EPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNE 1262
E + G+ VD C S+ C NG TC++ + + C+C + G C +
Sbjct: 121 ERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSG- 179
Query: 1263 KTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP---CVNGGLCQDLLN-- 1317
T L+C NGG C C C P G C D+C CV+ G+C+DL+
Sbjct: 180 -TPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVH-GICEDLMREQ 237
Query: 1318 ----KFQCLCDVAF 1327
K+ C+CD +
Sbjct: 238 AGEPKYSCVCDAGW 251
Score = 53.1 bits (126), Expect = 2e-06
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 1251 QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDEC---ASDP-- 1305
Q + VC + C NGG C C+C P + G C D++EC + P
Sbjct: 128 QQTVDKKVCSSNP----CQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS 183
Query: 1306 CVNGGLCQDLLNKFQCLCDVAFAGERC 1332
C NGG C + + + C C G +C
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQC 210
Score = 48.5 bits (114), Expect = 4e-05
Identities = 38/153 (24%), Positives = 60/153 (39%), Gaps = 29/153 (18%)
Query: 825 EKGDVIYIGGLPDKQE--------TELNGGFFKGCIQDVRLNNQNLEFFPN-----PTNN 871
E+G+++++ G E +LN C+ ++ N +++ P N
Sbjct: 47 ERGNLVFLTGSAQNIEFRTGSLGKIKLNDEDLSECLHQIQKNKEDIIELKGSAIGLPQNI 106
Query: 872 AS----LNPVLVNVTQGCAG------DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKA 921
+S LN LV++ + G C SNPC NGG C + D F C CP G
Sbjct: 107 SSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPL 166
Query: 922 CE-EVQWCGF-----SPCPHGAQCQPVLQGFEC 948
C +V C C +G C + + C
Sbjct: 167 CSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/54 (46%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 879 VNVTQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFS 931
VN T+ N C SNPC NGG C D FSC C L +G C+ Q CG S
Sbjct: 427 VNCTENI---NECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGES 477
Score = 42.7 bits (99), Expect = 0.002
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 884 GCAG-DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQP 941
GC N C S+PC NG C + C C + +G C E + C +PC +G C
Sbjct: 391 GCVQLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVD 449
Query: 942 VLQGFECIANAVFNGQSGQILFRSNGNITRELTNITFGFRTRDANVI 988
+ F C ++ G Q+ + G + N +F +R+ D +
Sbjct: 450 GVDSFSCECTRLWTGALCQVPQQVCGESLSGI-NGSFSYRSPDVGYV 495
Score = 40.0 bits (92), Expect = 0.016
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 671 VRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
V K C S PCQ+ G C+NL S+ C C ++GP C
Sbjct: 131 VDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLC 167
Score = 35.4 bits (80), Expect = 0.39
Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 11/67 (16%)
Query: 896 CHNGGVCHSRWDDFSCSCPALTSGKAC----EEVQWCGFSPCPHGAQCQPVLQ------G 945
C NGG C + +SC CP T G C ++ + + C HG C+ +++
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPK 242
Query: 946 FECIANA 952
+ C+ +A
Sbjct: 243 YSCVCDA 249
Score = 34.3 bits (77), Expect = 0.87
Identities = 13/31 (41%), Positives = 16/31 (51%)
Query: 681 CQSRGRCINLWLSYQCDCHRPYEGPNCLREY 711
CQ+ G C+N SY C C GP C +Y
Sbjct: 184 CQNGGTCVNTMGSYSCHCPPETYGPQCASKY 214
Score = 33.9 bits (76), Expect = 1.1
Identities = 13/31 (41%), Positives = 15/31 (48%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCS 57
C +N CLSN C N TC D C C+
Sbjct: 429 CTENINECLSNPCLNGGTCVDGVDSFSCECT 459
Score = 32.0 bits (71), Expect = 4.3
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 669 GCVR-KDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
GCV+ + C S PC + G+CI+ Y C C + G NC
Sbjct: 391 GCVQLSNICLSHPCLN-GQCIDTVSGYFCKCDSGWTGVNC 429
Score = 31.2 bits (69), Expect = 7.3
Identities = 12/32 (37%), Positives = 18/32 (56%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
C S PC + G C++ S+ C+C R + G C
Sbjct: 436 CLSNPCLNGGTCVDGVDSFSCECTRLWTGALC 467
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 158 bits (399), Expect = 4e-38
Identities = 145/491 (29%), Positives = 198/491 (40%), Gaps = 104/491 (21%)
Query: 60 ANNLDKD-CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTI----------CE 108
A LD D C + PC C+ NTPG SFLC CP GY C
Sbjct: 558 AECLDVDECHRVPPPCDLGRCE------NTPG--SFLCVCPAGYQAAPHGASCQDVDECT 609
Query: 109 TTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDG 166
+ G CG+ G C P C+CPAG+ G CE D DECA P C G C +
Sbjct: 610 QSPGLCGR------GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR-CDNT 662
Query: 167 IDGYSCFCVPGYQGRH----CDLEVDECA-SDPCKNEATCLNEIGRYTCICPH----NYS 217
+ C C G++ R C +VDECA S P C N G + C+CP N +
Sbjct: 663 AGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTA 721
Query: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE----LNTDECAS--QPC 271
G CE ++DEC + G C ++ G++ C P G H + DEC+S PC
Sbjct: 722 GSECE-DVDECENHLACPGQECVNSPGSFQCRTCPS--GHHLHRGRCTDVDECSSGAPPC 778
Query: 272 LHGGLCVDGENRYSCNCTG-----SGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
G C + E + C+C SG G C + C + C ++ ++ C
Sbjct: 779 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLEGDFCFPHGECLNTDGSFACT 837
Query: 327 CWPGYT----GAQCEIDLNECNSNP-CQSN-----------------------GECVELS 358
C PGY GA C +D++EC+ CQS C+++
Sbjct: 838 CAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVD 896
Query: 359 SEKQYGRITGLPSSFSYHEASGYVCI--CQPGFTGIHCE-----EDVNECSSNPCQNGGT 411
++ G S + Y C+ C PG+ H +DV+EC + G
Sbjct: 897 ECRERGPAL-CGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICGA 952
Query: 412 --CENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF--QDGQHGF 467
CEN PG+Y C D + GG C D+ +C N C H Q+ F
Sbjct: 953 QRCENTPGSYRCTPACDPGYQPTPGG-GCQDV------DECRNRSFCGAHAVCQNLPGSF 1005
Query: 468 SCLCPSGYTGS 478
CLC GY G+
Sbjct: 1006 QCLCDQGYEGA 1016
Score = 151 bits (381), Expect = 5e-36
Identities = 124/429 (28%), Positives = 175/429 (40%), Gaps = 55/429 (12%)
Query: 24 NSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANN-LDKD-CDNMKDPCFSNPCQG 81
+ C +N C C + + + D+ S +D D C + PC C+
Sbjct: 479 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE- 537
Query: 82 SATCVNTPGERSFLCKCPPGYSG----TICETTIGSCGK--NSCQHGGICHQDPIYPVCI 135
N+PG SF C C PG+ C + C + C G C P +C+
Sbjct: 538 -----NSPG--SFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGR-CENTPGSFLCV 588
Query: 136 CPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
CPAGY G C+ D DEC SP C GA C++ + C C G++G C+ +VDE
Sbjct: 589 CPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDE 646
Query: 190 CASDPCK-NEATCLNEIGRYTCICPHNYS----GVNCELEIDECWSQP--CLNGATCQDA 242
CA +P C N G + C CP + G C+ ++DEC P C G C++
Sbjct: 647 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR-CENT 704
Query: 243 LGAYFCDCAPGF----LGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGF---TG 295
G++ C C GF G CE + DEC + G CV+ + C SG G
Sbjct: 705 EGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 763
Query: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECV 355
+ + PC + C ++ ++ C C PGY PC EC+
Sbjct: 764 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR-------PGPCADVNECL 816
Query: 356 ELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENL 415
E +G SF+ A GY +PG G C DV+ECS G C N
Sbjct: 817 EGDFCFPHGECLNTDGSFACTCAPGY----RPGPRGASCL-DVDECSEEDLCQSGICTNT 871
Query: 416 PGNYTCHCP 424
G++ C CP
Sbjct: 872 DGSFECICP 880
Score = 86.7 bits (213), Expect = 1e-16
Identities = 122/492 (24%), Positives = 174/492 (35%), Gaps = 120/492 (24%)
Query: 39 CQNNSTCKDFSKDNDCSCSD---TANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFL 95
C + C + CSC+ + C ++ + + C C+NT G SF
Sbjct: 778 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG--SFA 835
Query: 96 CKCPPGYS----GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG----RFCEI 147
C C PGY G C + C + GIC CICP G+ C +
Sbjct: 836 CTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-L 893
Query: 148 DHDECAS-SPCQNGAV-CQDGIDGYSCF--CVPGYQGRH---CDLEVDECAS---DPCKN 197
D DEC P G+ C++ Y C C PGY CD +VDEC + C
Sbjct: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICGA 952
Query: 198 EATCLNEIGRYTCI--CPHNYS---GVNCELEIDECWSQP-CLNGATCQDALGAYFCDCA 251
+ C N G Y C C Y G C+ ++DEC ++ C A CQ+ G++ C C
Sbjct: 953 QR-CENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCD 1010
Query: 252 PGFLGD----HCELNTDECAS-QPCLHGGLCVDGENRYSCNC------------------ 288
G+ G HC ++ +EC + Q LC + E + C C
Sbjct: 1011 QGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR 1069
Query: 289 TGSG-FTGTHCET-LMPLCWSKP-----------------------CHNNATCEDSVDNY 323
T +G F G+ + P+ ++P C+ + D+ DN
Sbjct: 1070 TSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNI 1129
Query: 324 TCHCWPGYTGAQCEIDLNE-----CNSNPCQSNGECVELSSEKQYGRITGLPSS------ 372
T +C + E C C E E S +GR PS
Sbjct: 1130 LAR---NVTWQECCCTVGEGWGSGCRIQQCPGT-ETAEYQSLCPHGRGYLAPSGDLSLRR 1185
Query: 373 ----------------FSYHEASGYVCICQPGFTGIHCEE----DVNECSSN-PCQNGGT 411
+ A GY C C G+ H + D +EC+ P GG
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-YHTQRLECIDNDECADEEPACEGGR 1244
Query: 412 CENLPGNYTCHC 423
C N G+Y C C
Sbjct: 1245 CVNTVGSYHCTC 1256
Score = 86.3 bits (212), Expect = 2e-16
Identities = 60/208 (28%), Positives = 87/208 (41%), Gaps = 36/208 (17%)
Query: 1142 VCNSNPCLHG-GNCEDIYSSYHCSCPLGW----SGKHCELNIDEC--FSNPCIHGNCSDR 1194
+C NP + G G C S Y C+C G+ G C +++DEC PC G C +
Sbjct: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENS 539
Query: 1195 VAAYHCTCEPGYTG----VNCEVDIDNCQS--HQCANGATCISHTNGYSCLCFGNFT--- 1245
++ C C PG+ C +D+D C C G C + + C+C +
Sbjct: 540 PGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAP 597
Query: 1246 -GKFCRQ----SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE 1300
G C+ ++ P +CG G C +C+C GF G CE+D+DE
Sbjct: 598 HGASCQDVDECTQSPG-LCGR----------GACKNLPGSFRCVCPAGFRGSACEEDVDE 646
Query: 1301 CASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
CA +P G G C + F C C F
Sbjct: 647 CAQEPPPCGPGRCDNTAGSFHCACPAGF 674
Score = 86.3 bits (212), Expect = 2e-16
Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 60/246 (24%)
Query: 1152 GNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTC--- 1202
G C++ S+HC+CP G+ G C+ ++DEC +P C +G C + ++ C C
Sbjct: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMG 715
Query: 1203 -EPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF-------------------- 1241
+P G CE D+D C++H G C++ + C
Sbjct: 716 FQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 774
Query: 1242 --------------GNFTGKFCRQSRLPST---VCGNEKTNLT---CYNGGNCTEFQTEL 1281
G+F R PS C + L C+ G C
Sbjct: 775 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 834
Query: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLA 1337
C C PG+ G C D+DEC+ + G+C + F+C+C G R DLA
Sbjct: 835 ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICP---PGHRAGPDLA 890
Query: 1338 DDLISD 1343
L D
Sbjct: 891 SCLDVD 896
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/222 (30%), Positives = 91/222 (40%), Gaps = 34/222 (15%)
Query: 1135 TGCLQLNVCNS--NPCLHGGNCEDIYSSYHCSCPLGWSG----KHCELNIDECFS--NPC 1186
T C+ ++ C PC G CE+ S+ C C G+ C L++DEC PC
Sbjct: 516 TRCIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPC 573
Query: 1187 IHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLC 1240
G C + ++ C C GY G +C+ D+D C C GA C + + C+C
Sbjct: 574 DLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVC 631
Query: 1241 FGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEK 1296
F G C + C E G C C C GF G C+
Sbjct: 632 PAGFRGSACEED---VDECAQEPPPC---GPGRCDNTAGSFHCACPAGFRSRGPGAPCQ- 684
Query: 1297 DIDECA-SDPCVNGGLCQDLLNKFQCLCDVAF----AGERCE 1333
D+DECA S P G C++ FQC+C + F AG CE
Sbjct: 685 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 726
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/257 (26%), Positives = 107/257 (41%), Gaps = 66/257 (25%)
Query: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW---SGKHCEL-NIDECFSNP-CI-H 1188
C ++ C+S PC G+C + S+ CSC G+ SG+ +++EC C H
Sbjct: 765 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 824
Query: 1189 GNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF-GN 1243
G C + ++ CTC PGY G +C +D+D C C + + C+C G+
Sbjct: 825 GECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGH 883
Query: 1244 FTGKF---------CRQSRLPSTVCGNEKTNL---------------------TCYNGGN 1273
G CR+ R P+ +CG+++ TC +
Sbjct: 884 RAGPDLASCLDVDECRE-RGPA-LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 941
Query: 1274 CTEFQTEL-------------KCM--CRPGFT---GEWCEKDIDECASDP-CVNGGLCQD 1314
C E+ E+ +C C PG+ G C+ D+DEC + C +CQ+
Sbjct: 942 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQN 1000
Query: 1315 LLNKFQCLCDVAFAGER 1331
L FQCLCD + G R
Sbjct: 1001 LPGSFQCLCDQGYEGAR 1017
Score = 77.4 bits (189), Expect = 9e-14
Identities = 108/403 (26%), Positives = 144/403 (35%), Gaps = 95/403 (23%)
Query: 136 CPAGY--AGRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
CP G+ CE D DECA+ CQ+G C + GY+C C G+ D C S
Sbjct: 277 CPTGFERVNGSCE-DVDECATGGRCQHGE-CANTRGGYTCVCPDGFL---LDSSRSSCIS 331
Query: 193 DPCKNEAT--CLNEIGRYTCICP---HNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
+EA C + C P + + C + + W + C
Sbjct: 332 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI 391
Query: 248 CDCAPGFLGDHCEL--NTDECASQP---CLHGGLCVDGENRYSCNCTGSGFTGTHC---- 298
C PG+ +L NT +P L + +R S +GF TH
Sbjct: 392 CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPS-----AGFLPTHRLEPR 446
Query: 299 -----------ETLMPL--CWSKP-----------CHNN------ATCEDSVDNYTCHCW 328
E +P W+ P C N C YTC C
Sbjct: 447 PEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACD 506
Query: 329 PGYT----GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
G+ G +C ID++EC P C GR P SF C+
Sbjct: 507 SGFRLSPQGTRC-IDVDECRRVP----PPCAP-------GRCENSPGSFR--------CV 546
Query: 385 CQPGF-TGIHCEE--DVNECSS--NPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 439
C PGF G E DV+EC PC G CEN PG++ C CP + G C
Sbjct: 547 CGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPH--GASCQ 603
Query: 440 DILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
D+ CT L G C ++ F C+CP+G+ GS CE
Sbjct: 604 DVD-ECTQSPGLCGRGAC----KNLPGSFRCVCPAGFRGSACE 641
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/169 (29%), Positives = 71/169 (42%), Gaps = 19/169 (11%)
Query: 1181 CFSNP--CIHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQS--HQCANGATCISH 1232
C NP C G C R + Y C C+ G+ G C +D+D C+ CA G C +
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENS 539
Query: 1233 TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT-- 1290
+ C+C F L C + C + G C C+C G+
Sbjct: 540 PGSFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPC-DLGRCENTPGSFLCVCPAGYQAA 596
Query: 1291 --GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAGERCEVDL 1336
G C+ D+DEC P + G G C++L F+C+C F G CE D+
Sbjct: 597 PHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 644
Score = 64.3 bits (155), Expect = 8e-10
Identities = 61/208 (29%), Positives = 83/208 (39%), Gaps = 36/208 (17%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCS-------DTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C + +C C D A+ LD D + P GS C
Sbjct: 857 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALC----GSQRCE 912
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGK-NSCQHGGI-------CHQDPIYPVCI--C 136
N+PG + C PGY G+C + CQ G C P C C
Sbjct: 913 NSPGSYRCVRDCDPGYHAG----PEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPAC 968
Query: 137 PAGYA---GRFCEIDHDECAS-SPCQNGAVCQDGIDGYSCFCVPGYQ----GRHCDLEVD 188
GY G C+ D DEC + S C AVCQ+ + C C GY+ GRHC ++V+
Sbjct: 969 DPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVN 1026
Query: 189 ECAS-DPCKNEATCLNEIGRYTCICPHN 215
EC + A C N G + C+CP++
Sbjct: 1027 ECETLQGVCGAALCENVEGSFLCVCPNS 1054
Score = 64.3 bits (155), Expect = 8e-10
Identities = 76/313 (24%), Positives = 104/313 (33%), Gaps = 64/313 (20%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
C + C+N + D T +D D ++ F C A C N PG S
Sbjct: 950 CGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSF---CGAHAVCQNLPG--S 1004
Query: 94 FLCKCPPGYSGTI----------CETTIGSCGKNSCQHGG-----ICHQ-----DPIYPV 133
F C C GY G CET G CG C++ +C DP+
Sbjct: 1005 FQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGR 1064
Query: 134 CICPAGYAGRFCEIDHDECAS----------------SPCQNGAVCQDGIDGYSCFCVP- 176
C+ P AG F AS S + G V + Y P
Sbjct: 1065 CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPD 1124
Query: 177 --------GYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYS------GVNCE 222
+ C V E C+ + E Y +CPH ++
Sbjct: 1125 ACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1184
Query: 223 LEIDECW---SQPCLNGATCQDALGAYFCDCAPGFLGDHCEL---NTDECASQ-PCLHGG 275
++DEC Q C +G C + Y C C+ G+ L + DECA + P GG
Sbjct: 1185 RDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGG 1243
Query: 276 LCVDGENRYSCNC 288
CV+ Y C C
Sbjct: 1244 RCVNTVGSYHCTC 1256
Score = 47.4 bits (111), Expect = 1e-04
Identities = 71/283 (25%), Positives = 98/283 (34%), Gaps = 75/283 (26%)
Query: 39 CQNNSTCKDFSKDNDCSCS-------DTANNLD-KDCDNMKDPCFSNPCQGSATCVNTPG 90
C ++ C++ C C D + +D +C+ ++ C G+A C N G
Sbjct: 992 CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC------GAALCENVEG 1045
Query: 91 ERSFLCKCPPGYSGTICETTIGSCGKNSCQHG---GICHQDPIYPVCIC----------- 136
SFLC CP S + G C G G Q P PV
Sbjct: 1046 --SFLCVCPN--SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRP 1101
Query: 137 ------PAGYAGRFCEIDH---DECASSPCQN--------------GAVCQ----DGIDG 169
P G R C D D C + +N G+ C+ G +
Sbjct: 1102 STPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTET 1161
Query: 170 --YSCFCVPG--YQGRHCDL----EVDECA---SDPCKNEATCLNEIGRYTCICPHNYSG 218
Y C G Y DL +VDEC CK+ C+N Y+C C + Y
Sbjct: 1162 AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS-GVCVNTAPGYSCYCSNGYYY 1220
Query: 219 VNCELEI---DECWSQ-PCLNGATCQDALGAYFCDCAPGFLGD 257
LE DEC + P G C + +G+Y C C P + D
Sbjct: 1221 HTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1263
Score = 39.3 bits (90), Expect = 0.027
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 885 CAGDNSCKSNPCHNG-GVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHG-AQCQP 941
C + C +P G G C + F C CPA G ACEE V C P P G +C
Sbjct: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDN 661
Query: 942 VLQGFECIANAVFNGQ 957
F C A F +
Sbjct: 662 TAGSFHCACPAGFRSR 677
Score = 38.9 bits (89), Expect = 0.035
Identities = 29/125 (23%), Positives = 44/125 (35%), Gaps = 12/125 (9%)
Query: 1172 KHCELNIDECFSNPCIHGNC-SDRVAAYHCTCEPG--YTGVNCEV----DIDNCQ--SHQ 1222
+ C + E + + C C A Y C G Y + ++ D+D CQ Q
Sbjct: 1137 QECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1196
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELK 1282
C++ GYSC C + R + + C +E+ GG C
Sbjct: 1197 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE---PACEGGRCVNTVGSYH 1253
Query: 1283 CMCRP 1287
C C P
Sbjct: 1254 CTCEP 1258
Score = 38.9 bits (89), Expect = 0.035
Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 20/129 (15%)
Query: 119 CQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDECASS-PCQNGAVCQDGIDGYSCFC 174
C+ G + P Y C C GY R ID+DECA P G C + + Y C C
Sbjct: 1198 CKSGVCVNTAPGYS-CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Query: 175 VP-----GYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPH-----NYSGVNCELE 224
P G Q R C + D N C E+G +C H + C
Sbjct: 1257 EPPLVLDGSQ-RRCVSNESQSLDD---NLGVCWQEVGA-DLVCSHPRLDRQATYTECCCL 1311
Query: 225 IDECWSQPC 233
E W C
Sbjct: 1312 YGEAWGMDC 1320
Score = 38.9 bits (89), Expect = 0.035
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN-EKTNLTCYNGGNCTEFQTEL 1281
C NG C+ G++C CF + R + + C E + C N C
Sbjct: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDGSF 1533
Query: 1282 KCMCRPGF 1289
+C+CRPGF
Sbjct: 1534 RCICRPGF 1541
Score = 38.1 bits (87), Expect = 0.060
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 5/58 (8%)
Query: 1152 GNCEDIYSSYHCSCPLGWSGKHCELNI---DECFSNP--CIHGNCSDRVAAYHCTCEP 1204
G C + Y C C G+ L DEC C G C + V +YHCTCEP
Sbjct: 1201 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
Score = 37.0 bits (84), Expect = 0.13
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 11/99 (11%)
Query: 1167 LGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVN--CEVDIDNCQSHQCA 1224
L W C+L + GN S+RV+A C G+ VN CE D+D C +
Sbjct: 250 LAWGVHDCQLCSERL-------GN-SERVSAPDGPCPTGFERVNGSCE-DVDECATGGRC 300
Query: 1225 NGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEK 1263
C + GY+C+C F R S + V K
Sbjct: 301 QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAK 339
Score = 36.2 bits (82), Expect = 0.23
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 13/85 (15%)
Query: 184 DLEVDECAS-DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC-----WSQPC 233
+LE +EC D C N C+ +TC C Y + + C ++I+EC S C
Sbjct: 1464 ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1521
Query: 234 LNGATCQDALGAYFCDCAPGFLGDH 258
+N A C + G++ C C PGF H
Sbjct: 1522 VN-ARCLNTDGSFRCICRPGFAPTH 1545
Score = 35.8 bits (81), Expect = 0.30
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 29/89 (32%)
Query: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECN----SNPCQSNGECVELSSEKQYG 364
N C + +TC C+ GY T C +D+NEC+ ++P N C+
Sbjct: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTD------ 1530
Query: 365 RITGLPSSFSYHEASGYVCICQPGFTGIH 393
+ CIC+PGF H
Sbjct: 1531 --------------GSFRCICRPGFAPTH 1545
Score = 34.7 bits (78), Expect = 0.66
Identities = 36/158 (22%), Positives = 53/158 (33%), Gaps = 28/158 (17%)
Query: 1180 ECFSNPCIHGNCSDRVAA----YHCTCEPGYT-GVNCEVDIDNCQSHQCANGATCISHTN 1234
EC+ + C + +A C C G G C I C + A + H
Sbjct: 1115 ECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGR 1172
Query: 1235 GYSCLCFGNFTGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
GY G+ + + R S VC N +CY L+C+
Sbjct: 1173 GYLAPS-GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI--- 1228
Query: 1288 GFTGEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCD 1324
D DECA + P GG C + + + C C+
Sbjct: 1229 ---------DNDECADEEPACEGGRCVNTVGSYHCTCE 1257
Score = 33.9 bits (76), Expect = 1.1
Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 12/57 (21%)
Query: 100 PGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP 156
PG+ +C C +GG+C + C+CP +AG+FC++ H A P
Sbjct: 79 PGFRAFLCPLI--------CHNGGVCVKPDR---CLCPPDFAGKFCQL-HSSGARPP 123
Score = 32.3 bits (72), Expect = 3.3
Identities = 12/30 (40%), Positives = 19/30 (63%), Gaps = 3/30 (10%)
Query: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
L C+NGG C + +C+C P F G++C+
Sbjct: 88 LICHNGGVCVKPD---RCLCPPDFAGKFCQ 114
Score = 32.3 bits (72), Expect = 3.3
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 6/66 (9%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPA----LTSGKACEEVQWC-GFSPCPHGAQCQPV 942
D +S P G C + F C CP T+G CE+V C CP G +C
Sbjct: 687 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP-GQECVNS 745
Query: 943 LQGFEC 948
F+C
Sbjct: 746 PGSFQC 751
Score = 32.0 bits (71), Expect = 4.3
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 19/94 (20%)
Query: 1137 CLQLNVC-NSNPCLHGGNCEDIYSSYHCSCP----LGWSGKHC--------ELNIDECFS 1183
C+ + C + P GG C + SYHC+C L S + C + N+ C+
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
Query: 1184 NPCIHGNCS----DRVAAY-HCTCEPGYT-GVNC 1211
CS DR A Y C C G G++C
Sbjct: 1287 EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDC 1320
Score = 32.0 bits (71), Expect = 4.3
Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 30/118 (25%)
Query: 1115 GFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS---G 1171
G + +P EE L+ ++ GC G C + + C C G+
Sbjct: 1456 GSLAEPYEE--LEAEECGILDGCTN------------GRCVRVPEGFTCRCFDGYRLDMT 1501
Query: 1172 KHCELNIDEC-----FSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCA 1224
+ ++I+EC S C++ C + ++ C C PG+ + Q H CA
Sbjct: 1502 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH--------QPHHCA 1551
Score = 31.6 bits (70), Expect = 5.6
Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 670 CVRKDWC-ESQPCQSRGRCINLWLSYQCDCHRP 701
C+ D C + +P GRC+N SY C C P
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1259
Score = 31.2 bits (69), Expect = 7.3
Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 15/97 (15%)
Query: 102 YSGTICET----TIGSCGKNSCQHGGICHQDPIYPVCICPAGYA---GRFCEIDHDEC-- 152
Y+G++ E CG G C + P C C GY R +D +EC
Sbjct: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1513
Query: 153 --ASSPCQNGAVCQDGIDGYSCFCVPGY----QGRHC 183
A+SP A C + + C C PG+ Q HC
Sbjct: 1514 AEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 30.8 bits (68), Expect = 9.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 660 SGSSLNVKAGCVRKDWCES--QPCQSRGRCINLWLSYQCDCHRPYEGPN 706
SG L+ + C D C S PC G C N S++C C Y P+
Sbjct: 756 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 803
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 158 bits (399), Expect = 4e-38
Identities = 145/491 (29%), Positives = 198/491 (40%), Gaps = 104/491 (21%)
Query: 60 ANNLDKD-CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTI----------CE 108
A LD D C + PC C+ NTPG SFLC CP GY C
Sbjct: 588 AECLDVDECHRVPPPCDLGRCE------NTPG--SFLCVCPAGYQAAPHGASCQDVDECT 639
Query: 109 TTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDG 166
+ G CG+ G C P C+CPAG+ G CE D DECA P C G C +
Sbjct: 640 QSPGLCGR------GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR-CDNT 692
Query: 167 IDGYSCFCVPGYQGRH----CDLEVDECA-SDPCKNEATCLNEIGRYTCICPH----NYS 217
+ C C G++ R C +VDECA S P C N G + C+CP N +
Sbjct: 693 AGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTA 751
Query: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE----LNTDECAS--QPC 271
G CE ++DEC + G C ++ G++ C P G H + DEC+S PC
Sbjct: 752 GSECE-DVDECENHLACPGQECVNSPGSFQCRTCPS--GHHLHRGRCTDVDECSSGAPPC 808
Query: 272 LHGGLCVDGENRYSCNCTG-----SGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
G C + E + C+C SG G C + C + C ++ ++ C
Sbjct: 809 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLEGDFCFPHGECLNTDGSFACT 867
Query: 327 CWPGYT----GAQCEIDLNECNSNP-CQSN-----------------------GECVELS 358
C PGY GA C +D++EC+ CQS C+++
Sbjct: 868 CAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVD 926
Query: 359 SEKQYGRITGLPSSFSYHEASGYVCI--CQPGFTGIHCE-----EDVNECSSNPCQNGGT 411
++ G S + Y C+ C PG+ H +DV+EC + G
Sbjct: 927 ECRERGPAL-CGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICGA 982
Query: 412 --CENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF--QDGQHGF 467
CEN PG+Y C D + GG C D+ +C N C H Q+ F
Sbjct: 983 QRCENTPGSYRCTPACDPGYQPTPGG-GCQDV------DECRNRSFCGAHAVCQNLPGSF 1035
Query: 468 SCLCPSGYTGS 478
CLC GY G+
Sbjct: 1036 QCLCDQGYEGA 1046
Score = 151 bits (381), Expect = 5e-36
Identities = 124/429 (28%), Positives = 175/429 (40%), Gaps = 55/429 (12%)
Query: 24 NSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANN-LDKD-CDNMKDPCFSNPCQG 81
+ C +N C C + + + D+ S +D D C + PC C+
Sbjct: 509 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE- 567
Query: 82 SATCVNTPGERSFLCKCPPGYSG----TICETTIGSCGK--NSCQHGGICHQDPIYPVCI 135
N+PG SF C C PG+ C + C + C G C P +C+
Sbjct: 568 -----NSPG--SFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGR-CENTPGSFLCV 618
Query: 136 CPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
CPAGY G C+ D DEC SP C GA C++ + C C G++G C+ +VDE
Sbjct: 619 CPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDE 676
Query: 190 CASDPCK-NEATCLNEIGRYTCICPHNYS----GVNCELEIDECWSQP--CLNGATCQDA 242
CA +P C N G + C CP + G C+ ++DEC P C G C++
Sbjct: 677 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR-CENT 734
Query: 243 LGAYFCDCAPGF----LGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGF---TG 295
G++ C C GF G CE + DEC + G CV+ + C SG G
Sbjct: 735 EGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 793
Query: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECV 355
+ + PC + C ++ ++ C C PGY PC EC+
Sbjct: 794 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR-------PGPCADVNECL 846
Query: 356 ELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENL 415
E +G SF+ A GY +PG G C DV+ECS G C N
Sbjct: 847 EGDFCFPHGECLNTDGSFACTCAPGY----RPGPRGASCL-DVDECSEEDLCQSGICTNT 901
Query: 416 PGNYTCHCP 424
G++ C CP
Sbjct: 902 DGSFECICP 910
Score = 86.7 bits (213), Expect = 1e-16
Identities = 122/492 (24%), Positives = 174/492 (35%), Gaps = 120/492 (24%)
Query: 39 CQNNSTCKDFSKDNDCSCSD---TANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFL 95
C + C + CSC+ + C ++ + + C C+NT G SF
Sbjct: 808 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG--SFA 865
Query: 96 CKCPPGYS----GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG----RFCEI 147
C C PGY G C + C + GIC CICP G+ C +
Sbjct: 866 CTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-L 923
Query: 148 DHDECAS-SPCQNGAV-CQDGIDGYSCF--CVPGYQGRH---CDLEVDECAS---DPCKN 197
D DEC P G+ C++ Y C C PGY CD +VDEC + C
Sbjct: 924 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICGA 982
Query: 198 EATCLNEIGRYTCI--CPHNYS---GVNCELEIDECWSQP-CLNGATCQDALGAYFCDCA 251
+ C N G Y C C Y G C+ ++DEC ++ C A CQ+ G++ C C
Sbjct: 983 QR-CENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCD 1040
Query: 252 PGFLGD----HCELNTDECAS-QPCLHGGLCVDGENRYSCNC------------------ 288
G+ G HC ++ +EC + Q LC + E + C C
Sbjct: 1041 QGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR 1099
Query: 289 TGSG-FTGTHCET-LMPLCWSKP-----------------------CHNNATCEDSVDNY 323
T +G F G+ + P+ ++P C+ + D+ DN
Sbjct: 1100 TSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNI 1159
Query: 324 TCHCWPGYTGAQCEIDLNE-----CNSNPCQSNGECVELSSEKQYGRITGLPSS------ 372
T +C + E C C E E S +GR PS
Sbjct: 1160 LAR---NVTWQECCCTVGEGWGSGCRIQQCPGT-ETAEYQSLCPHGRGYLAPSGDLSLRR 1215
Query: 373 ----------------FSYHEASGYVCICQPGFTGIHCEE----DVNECSSN-PCQNGGT 411
+ A GY C C G+ H + D +EC+ P GG
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-YHTQRLECIDNDECADEEPACEGGR 1274
Query: 412 CENLPGNYTCHC 423
C N G+Y C C
Sbjct: 1275 CVNTVGSYHCTC 1286
Score = 86.3 bits (212), Expect = 2e-16
Identities = 60/208 (28%), Positives = 87/208 (41%), Gaps = 36/208 (17%)
Query: 1142 VCNSNPCLHG-GNCEDIYSSYHCSCPLGW----SGKHCELNIDEC--FSNPCIHGNCSDR 1194
+C NP + G G C S Y C+C G+ G C +++DEC PC G C +
Sbjct: 511 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENS 569
Query: 1195 VAAYHCTCEPGYTG----VNCEVDIDNCQS--HQCANGATCISHTNGYSCLCFGNFT--- 1245
++ C C PG+ C +D+D C C G C + + C+C +
Sbjct: 570 PGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAP 627
Query: 1246 -GKFCRQ----SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE 1300
G C+ ++ P +CG G C +C+C GF G CE+D+DE
Sbjct: 628 HGASCQDVDECTQSPG-LCGR----------GACKNLPGSFRCVCPAGFRGSACEEDVDE 676
Query: 1301 CASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
CA +P G G C + F C C F
Sbjct: 677 CAQEPPPCGPGRCDNTAGSFHCACPAGF 704
Score = 86.3 bits (212), Expect = 2e-16
Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 60/246 (24%)
Query: 1152 GNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTC--- 1202
G C++ S+HC+CP G+ G C+ ++DEC +P C +G C + ++ C C
Sbjct: 687 GRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMG 745
Query: 1203 -EPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF-------------------- 1241
+P G CE D+D C++H G C++ + C
Sbjct: 746 FQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 804
Query: 1242 --------------GNFTGKFCRQSRLPST---VCGNEKTNLT---CYNGGNCTEFQTEL 1281
G+F R PS C + L C+ G C
Sbjct: 805 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 864
Query: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLA 1337
C C PG+ G C D+DEC+ + G+C + F+C+C G R DLA
Sbjct: 865 ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICP---PGHRAGPDLA 920
Query: 1338 DDLISD 1343
L D
Sbjct: 921 SCLDVD 926
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/222 (30%), Positives = 91/222 (40%), Gaps = 34/222 (15%)
Query: 1135 TGCLQLNVCNS--NPCLHGGNCEDIYSSYHCSCPLGWSG----KHCELNIDECFS--NPC 1186
T C+ ++ C PC G CE+ S+ C C G+ C L++DEC PC
Sbjct: 546 TRCIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPC 603
Query: 1187 IHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLC 1240
G C + ++ C C GY G +C+ D+D C C GA C + + C+C
Sbjct: 604 DLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVC 661
Query: 1241 FGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEK 1296
F G C + C E G C C C GF G C+
Sbjct: 662 PAGFRGSACEED---VDECAQEPPPC---GPGRCDNTAGSFHCACPAGFRSRGPGAPCQ- 714
Query: 1297 DIDECA-SDPCVNGGLCQDLLNKFQCLCDVAF----AGERCE 1333
D+DECA S P G C++ FQC+C + F AG CE
Sbjct: 715 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 756
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/257 (26%), Positives = 107/257 (41%), Gaps = 66/257 (25%)
Query: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW---SGKHCEL-NIDECFSNP-CI-H 1188
C ++ C+S PC G+C + S+ CSC G+ SG+ +++EC C H
Sbjct: 795 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 854
Query: 1189 GNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF-GN 1243
G C + ++ CTC PGY G +C +D+D C C + + C+C G+
Sbjct: 855 GECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGH 913
Query: 1244 FTGKF---------CRQSRLPSTVCGNEKTNL---------------------TCYNGGN 1273
G CR+ R P+ +CG+++ TC +
Sbjct: 914 RAGPDLASCLDVDECRE-RGPA-LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 971
Query: 1274 CTEFQTEL-------------KCM--CRPGFT---GEWCEKDIDECASDP-CVNGGLCQD 1314
C E+ E+ +C C PG+ G C+ D+DEC + C +CQ+
Sbjct: 972 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQN 1030
Query: 1315 LLNKFQCLCDVAFAGER 1331
L FQCLCD + G R
Sbjct: 1031 LPGSFQCLCDQGYEGAR 1047
Score = 77.4 bits (189), Expect = 9e-14
Identities = 108/403 (26%), Positives = 144/403 (35%), Gaps = 95/403 (23%)
Query: 136 CPAGY--AGRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
CP G+ CE D DECA+ CQ+G C + GY+C C G+ D C S
Sbjct: 307 CPTGFERVNGSCE-DVDECATGGRCQHGE-CANTRGGYTCVCPDGFL---LDSSRSSCIS 361
Query: 193 DPCKNEAT--CLNEIGRYTCICP---HNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
+EA C + C P + + C + + W + C
Sbjct: 362 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI 421
Query: 248 CDCAPGFLGDHCEL--NTDECASQP---CLHGGLCVDGENRYSCNCTGSGFTGTHC---- 298
C PG+ +L NT +P L + +R S +GF TH
Sbjct: 422 CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPS-----AGFLPTHRLEPR 476
Query: 299 -----------ETLMPL--CWSKP-----------CHNN------ATCEDSVDNYTCHCW 328
E +P W+ P C N C YTC C
Sbjct: 477 PEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACD 536
Query: 329 PGYT----GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
G+ G +C ID++EC P C GR P SF C+
Sbjct: 537 SGFRLSPQGTRC-IDVDECRRVP----PPCAP-------GRCENSPGSFR--------CV 576
Query: 385 CQPGF-TGIHCEE--DVNECSS--NPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 439
C PGF G E DV+EC PC G CEN PG++ C CP + G C
Sbjct: 577 CGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPH--GASCQ 633
Query: 440 DILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
D+ CT L G C ++ F C+CP+G+ GS CE
Sbjct: 634 DVD-ECTQSPGLCGRGAC----KNLPGSFRCVCPAGFRGSACE 671
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/169 (29%), Positives = 71/169 (42%), Gaps = 19/169 (11%)
Query: 1181 CFSNP--CIHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQS--HQCANGATCISH 1232
C NP C G C R + Y C C+ G+ G C +D+D C+ CA G C +
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENS 569
Query: 1233 TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT-- 1290
+ C+C F L C + C + G C C+C G+
Sbjct: 570 PGSFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPC-DLGRCENTPGSFLCVCPAGYQAA 626
Query: 1291 --GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAGERCEVDL 1336
G C+ D+DEC P + G G C++L F+C+C F G CE D+
Sbjct: 627 PHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 674
Score = 64.3 bits (155), Expect = 8e-10
Identities = 61/208 (29%), Positives = 83/208 (39%), Gaps = 36/208 (17%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCS-------DTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C + +C C D A+ LD D + P GS C
Sbjct: 887 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALC----GSQRCE 942
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGK-NSCQHGGI-------CHQDPIYPVCI--C 136
N+PG + C PGY G+C + CQ G C P C C
Sbjct: 943 NSPGSYRCVRDCDPGYHAG----PEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPAC 998
Query: 137 PAGYA---GRFCEIDHDECAS-SPCQNGAVCQDGIDGYSCFCVPGYQ----GRHCDLEVD 188
GY G C+ D DEC + S C AVCQ+ + C C GY+ GRHC ++V+
Sbjct: 999 DPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVN 1056
Query: 189 ECAS-DPCKNEATCLNEIGRYTCICPHN 215
EC + A C N G + C+CP++
Sbjct: 1057 ECETLQGVCGAALCENVEGSFLCVCPNS 1084
Score = 64.3 bits (155), Expect = 8e-10
Identities = 76/313 (24%), Positives = 104/313 (33%), Gaps = 64/313 (20%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
C + C+N + D T +D D ++ F C A C N PG S
Sbjct: 980 CGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSF---CGAHAVCQNLPG--S 1034
Query: 94 FLCKCPPGYSGTI----------CETTIGSCGKNSCQHGG-----ICHQ-----DPIYPV 133
F C C GY G CET G CG C++ +C DP+
Sbjct: 1035 FQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGR 1094
Query: 134 CICPAGYAGRFCEIDHDECAS----------------SPCQNGAVCQDGIDGYSCFCVP- 176
C+ P AG F AS S + G V + Y P
Sbjct: 1095 CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPD 1154
Query: 177 --------GYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYS------GVNCE 222
+ C V E C+ + E Y +CPH ++
Sbjct: 1155 ACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1214
Query: 223 LEIDECW---SQPCLNGATCQDALGAYFCDCAPGFLGDHCEL---NTDECASQ-PCLHGG 275
++DEC Q C +G C + Y C C+ G+ L + DECA + P GG
Sbjct: 1215 RDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGG 1273
Query: 276 LCVDGENRYSCNC 288
CV+ Y C C
Sbjct: 1274 RCVNTVGSYHCTC 1286
Score = 47.4 bits (111), Expect = 1e-04
Identities = 71/283 (25%), Positives = 98/283 (34%), Gaps = 75/283 (26%)
Query: 39 CQNNSTCKDFSKDNDCSCS-------DTANNLD-KDCDNMKDPCFSNPCQGSATCVNTPG 90
C ++ C++ C C D + +D +C+ ++ C G+A C N G
Sbjct: 1022 CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC------GAALCENVEG 1075
Query: 91 ERSFLCKCPPGYSGTICETTIGSCGKNSCQHG---GICHQDPIYPVCIC----------- 136
SFLC CP S + G C G G Q P PV
Sbjct: 1076 --SFLCVCPN--SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRP 1131
Query: 137 ------PAGYAGRFCEIDH---DECASSPCQN--------------GAVCQ----DGIDG 169
P G R C D D C + +N G+ C+ G +
Sbjct: 1132 STPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTET 1191
Query: 170 --YSCFCVPG--YQGRHCDL----EVDECA---SDPCKNEATCLNEIGRYTCICPHNYSG 218
Y C G Y DL +VDEC CK+ C+N Y+C C + Y
Sbjct: 1192 AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS-GVCVNTAPGYSCYCSNGYYY 1250
Query: 219 VNCELEI---DECWSQ-PCLNGATCQDALGAYFCDCAPGFLGD 257
LE DEC + P G C + +G+Y C C P + D
Sbjct: 1251 HTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1293
Score = 39.3 bits (90), Expect = 0.027
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 885 CAGDNSCKSNPCHNG-GVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHG-AQCQP 941
C + C +P G G C + F C CPA G ACEE V C P P G +C
Sbjct: 632 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDN 691
Query: 942 VLQGFECIANAVFNGQ 957
F C A F +
Sbjct: 692 TAGSFHCACPAGFRSR 707
Score = 38.9 bits (89), Expect = 0.035
Identities = 29/125 (23%), Positives = 44/125 (35%), Gaps = 12/125 (9%)
Query: 1172 KHCELNIDECFSNPCIHGNC-SDRVAAYHCTCEPG--YTGVNCEV----DIDNCQ--SHQ 1222
+ C + E + + C C A Y C G Y + ++ D+D CQ Q
Sbjct: 1167 QECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1226
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELK 1282
C++ GYSC C + R + + C +E+ GG C
Sbjct: 1227 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE---PACEGGRCVNTVGSYH 1283
Query: 1283 CMCRP 1287
C C P
Sbjct: 1284 CTCEP 1288
Score = 38.9 bits (89), Expect = 0.035
Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 20/129 (15%)
Query: 119 CQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDECASS-PCQNGAVCQDGIDGYSCFC 174
C+ G + P Y C C GY R ID+DECA P G C + + Y C C
Sbjct: 1228 CKSGVCVNTAPGYS-CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Query: 175 VP-----GYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPH-----NYSGVNCELE 224
P G Q R C + D N C E+G +C H + C
Sbjct: 1287 EPPLVLDGSQ-RRCVSNESQSLDD---NLGVCWQEVGA-DLVCSHPRLDRQATYTECCCL 1341
Query: 225 IDECWSQPC 233
E W C
Sbjct: 1342 YGEAWGMDC 1350
Score = 38.9 bits (89), Expect = 0.035
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN-EKTNLTCYNGGNCTEFQTEL 1281
C NG C+ G++C CF + R + + C E + C N C
Sbjct: 1506 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDGSF 1563
Query: 1282 KCMCRPGF 1289
+C+CRPGF
Sbjct: 1564 RCICRPGF 1571
Score = 38.1 bits (87), Expect = 0.060
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 5/58 (8%)
Query: 1152 GNCEDIYSSYHCSCPLGWSGKHCELNI---DECFSNP--CIHGNCSDRVAAYHCTCEP 1204
G C + Y C C G+ L DEC C G C + V +YHCTCEP
Sbjct: 1231 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Score = 37.0 bits (84), Expect = 0.13
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 11/99 (11%)
Query: 1167 LGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVN--CEVDIDNCQSHQCA 1224
L W C+L + GN S+RV+A C G+ VN CE D+D C +
Sbjct: 280 LAWGVHDCQLCSERL-------GN-SERVSAPDGPCPTGFERVNGSCE-DVDECATGGRC 330
Query: 1225 NGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEK 1263
C + GY+C+C F R S + V K
Sbjct: 331 QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAK 369
Score = 36.2 bits (82), Expect = 0.23
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 13/85 (15%)
Query: 184 DLEVDECAS-DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC-----WSQPC 233
+LE +EC D C N C+ +TC C Y + + C ++I+EC S C
Sbjct: 1494 ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1551
Query: 234 LNGATCQDALGAYFCDCAPGFLGDH 258
+N A C + G++ C C PGF H
Sbjct: 1552 VN-ARCLNTDGSFRCICRPGFAPTH 1575
Score = 35.8 bits (81), Expect = 0.30
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 29/89 (32%)
Query: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECN----SNPCQSNGECVELSSEKQYG 364
N C + +TC C+ GY T C +D+NEC+ ++P N C+
Sbjct: 1508 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTD------ 1560
Query: 365 RITGLPSSFSYHEASGYVCICQPGFTGIH 393
+ CIC+PGF H
Sbjct: 1561 --------------GSFRCICRPGFAPTH 1575
Score = 35.4 bits (80), Expect = 0.39
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 17/73 (23%)
Query: 89 PGERSFLCKCPP-----GYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGR 143
PG R L + PP G + +C C +GG+C + C+CP +AG+
Sbjct: 93 PGGRGLLRRRPPQRAPAGKAPVLCPLI--------CHNGGVCVKPDR---CLCPPDFAGK 141
Query: 144 FCEIDHDECASSP 156
FC++ H A P
Sbjct: 142 FCQL-HSSGARPP 153
Score = 34.7 bits (78), Expect = 0.66
Identities = 36/158 (22%), Positives = 53/158 (33%), Gaps = 28/158 (17%)
Query: 1180 ECFSNPCIHGNCSDRVAA----YHCTCEPGYT-GVNCEVDIDNCQSHQCANGATCISHTN 1234
EC+ + C + +A C C G G C I C + A + H
Sbjct: 1145 ECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGR 1202
Query: 1235 GYSCLCFGNFTGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
GY G+ + + R S VC N +CY L+C+
Sbjct: 1203 GYLAPS-GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI--- 1258
Query: 1288 GFTGEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCD 1324
D DECA + P GG C + + + C C+
Sbjct: 1259 ---------DNDECADEEPACEGGRCVNTVGSYHCTCE 1287
Score = 32.3 bits (72), Expect = 3.3
Identities = 12/30 (40%), Positives = 19/30 (63%), Gaps = 3/30 (10%)
Query: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
L C+NGG C + +C+C P F G++C+
Sbjct: 118 LICHNGGVCVKPD---RCLCPPDFAGKFCQ 144
Score = 32.3 bits (72), Expect = 3.3
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 6/66 (9%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPA----LTSGKACEEVQWC-GFSPCPHGAQCQPV 942
D +S P G C + F C CP T+G CE+V C CP G +C
Sbjct: 717 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP-GQECVNS 775
Query: 943 LQGFEC 948
F+C
Sbjct: 776 PGSFQC 781
Score = 32.0 bits (71), Expect = 4.3
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 19/94 (20%)
Query: 1137 CLQLNVC-NSNPCLHGGNCEDIYSSYHCSCP----LGWSGKHC--------ELNIDECFS 1183
C+ + C + P GG C + SYHC+C L S + C + N+ C+
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1316
Query: 1184 NPCIHGNCS----DRVAAY-HCTCEPGYT-GVNC 1211
CS DR A Y C C G G++C
Sbjct: 1317 EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDC 1350
Score = 32.0 bits (71), Expect = 4.3
Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 30/118 (25%)
Query: 1115 GFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS---G 1171
G + +P EE L+ ++ GC G C + + C C G+
Sbjct: 1486 GSLAEPYEE--LEAEECGILDGCTN------------GRCVRVPEGFTCRCFDGYRLDMT 1531
Query: 1172 KHCELNIDEC-----FSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCA 1224
+ ++I+EC S C++ C + ++ C C PG+ + Q H CA
Sbjct: 1532 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH--------QPHHCA 1581
Score = 31.6 bits (70), Expect = 5.6
Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 670 CVRKDWC-ESQPCQSRGRCINLWLSYQCDCHRP 701
C+ D C + +P GRC+N SY C C P
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1289
Score = 31.2 bits (69), Expect = 7.3
Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 15/97 (15%)
Query: 102 YSGTICET----TIGSCGKNSCQHGGICHQDPIYPVCICPAGYA---GRFCEIDHDEC-- 152
Y+G++ E CG G C + P C C GY R +D +EC
Sbjct: 1484 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1543
Query: 153 --ASSPCQNGAVCQDGIDGYSCFCVPGY----QGRHC 183
A+SP A C + + C C PG+ Q HC
Sbjct: 1544 AEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 30.8 bits (68), Expect = 9.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 660 SGSSLNVKAGCVRKDWCES--QPCQSRGRCINLWLSYQCDCHRPYEGPN 706
SG L+ + C D C S PC G C N S++C C Y P+
Sbjct: 786 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 833
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 158 bits (399), Expect = 4e-38
Identities = 145/491 (29%), Positives = 198/491 (40%), Gaps = 104/491 (21%)
Query: 60 ANNLDKD-CDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTI----------CE 108
A LD D C + PC C+ NTPG SFLC CP GY C
Sbjct: 625 AECLDVDECHRVPPPCDLGRCE------NTPG--SFLCVCPAGYQAAPHGASCQDVDECT 676
Query: 109 TTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDG 166
+ G CG+ G C P C+CPAG+ G CE D DECA P C G C +
Sbjct: 677 QSPGLCGR------GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR-CDNT 729
Query: 167 IDGYSCFCVPGYQGRH----CDLEVDECA-SDPCKNEATCLNEIGRYTCICPH----NYS 217
+ C C G++ R C +VDECA S P C N G + C+CP N +
Sbjct: 730 AGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTA 788
Query: 218 GVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE----LNTDECAS--QPC 271
G CE ++DEC + G C ++ G++ C P G H + DEC+S PC
Sbjct: 789 GSECE-DVDECENHLACPGQECVNSPGSFQCRTCPS--GHHLHRGRCTDVDECSSGAPPC 845
Query: 272 LHGGLCVDGENRYSCNCTG-----SGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCH 326
G C + E + C+C SG G C + C + C ++ ++ C
Sbjct: 846 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECLEGDFCFPHGECLNTDGSFACT 904
Query: 327 CWPGYT----GAQCEIDLNECNSNP-CQSN-----------------------GECVELS 358
C PGY GA C +D++EC+ CQS C+++
Sbjct: 905 CAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVD 963
Query: 359 SEKQYGRITGLPSSFSYHEASGYVCI--CQPGFTGIHCE-----EDVNECSSNPCQNGGT 411
++ G S + Y C+ C PG+ H +DV+EC + G
Sbjct: 964 ECRERGPAL-CGSQRCENSPGSYRCVRDCDPGY---HAGPEGTCDDVDECQEYGPEICGA 1019
Query: 412 --CENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHF--QDGQHGF 467
CEN PG+Y C D + GG C D+ +C N C H Q+ F
Sbjct: 1020 QRCENTPGSYRCTPACDPGYQPTPGG-GCQDV------DECRNRSFCGAHAVCQNLPGSF 1072
Query: 468 SCLCPSGYTGS 478
CLC GY G+
Sbjct: 1073 QCLCDQGYEGA 1083
Score = 151 bits (381), Expect = 5e-36
Identities = 124/429 (28%), Positives = 175/429 (40%), Gaps = 55/429 (12%)
Query: 24 NSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANN-LDKD-CDNMKDPCFSNPCQG 81
+ C +N C C + + + D+ S +D D C + PC C+
Sbjct: 546 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCE- 604
Query: 82 SATCVNTPGERSFLCKCPPGYSG----TICETTIGSCGK--NSCQHGGICHQDPIYPVCI 135
N+PG SF C C PG+ C + C + C G C P +C+
Sbjct: 605 -----NSPG--SFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGR-CENTPGSFLCV 655
Query: 136 CPAGYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
CPAGY G C+ D DEC SP C GA C++ + C C G++G C+ +VDE
Sbjct: 656 CPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDE 713
Query: 190 CASDPCK-NEATCLNEIGRYTCICPHNYS----GVNCELEIDECWSQP--CLNGATCQDA 242
CA +P C N G + C CP + G C+ ++DEC P C G C++
Sbjct: 714 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR-CENT 771
Query: 243 LGAYFCDCAPGF----LGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGF---TG 295
G++ C C GF G CE + DEC + G CV+ + C SG G
Sbjct: 772 EGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 830
Query: 296 THCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECV 355
+ + PC + C ++ ++ C C PGY PC EC+
Sbjct: 831 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR-------PGPCADVNECL 883
Query: 356 ELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENL 415
E +G SF+ A GY +PG G C DV+ECS G C N
Sbjct: 884 EGDFCFPHGECLNTDGSFACTCAPGY----RPGPRGASCL-DVDECSEEDLCQSGICTNT 938
Query: 416 PGNYTCHCP 424
G++ C CP
Sbjct: 939 DGSFECICP 947
Score = 86.7 bits (213), Expect = 1e-16
Identities = 122/492 (24%), Positives = 174/492 (35%), Gaps = 120/492 (24%)
Query: 39 CQNNSTCKDFSKDNDCSCSD---TANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFL 95
C + C + CSC+ + C ++ + + C C+NT G SF
Sbjct: 845 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG--SFA 902
Query: 96 CKCPPGYS----GTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG----RFCEI 147
C C PGY G C + C + GIC CICP G+ C +
Sbjct: 903 CTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-L 960
Query: 148 DHDECAS-SPCQNGAV-CQDGIDGYSCF--CVPGYQGRH---CDLEVDECAS---DPCKN 197
D DEC P G+ C++ Y C C PGY CD +VDEC + C
Sbjct: 961 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICGA 1019
Query: 198 EATCLNEIGRYTCI--CPHNYS---GVNCELEIDECWSQP-CLNGATCQDALGAYFCDCA 251
+ C N G Y C C Y G C+ ++DEC ++ C A CQ+ G++ C C
Sbjct: 1020 QR-CENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCD 1077
Query: 252 PGFLGD----HCELNTDECAS-QPCLHGGLCVDGENRYSCNC------------------ 288
G+ G HC ++ +EC + Q LC + E + C C
Sbjct: 1078 QGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR 1136
Query: 289 TGSG-FTGTHCET-LMPLCWSKP-----------------------CHNNATCEDSVDNY 323
T +G F G+ + P+ ++P C+ + D+ DN
Sbjct: 1137 TSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNI 1196
Query: 324 TCHCWPGYTGAQCEIDLNE-----CNSNPCQSNGECVELSSEKQYGRITGLPSS------ 372
T +C + E C C E E S +GR PS
Sbjct: 1197 LAR---NVTWQECCCTVGEGWGSGCRIQQCPGT-ETAEYQSLCPHGRGYLAPSGDLSLRR 1252
Query: 373 ----------------FSYHEASGYVCICQPGFTGIHCEE----DVNECSSN-PCQNGGT 411
+ A GY C C G+ H + D +EC+ P GG
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-YHTQRLECIDNDECADEEPACEGGR 1311
Query: 412 CENLPGNYTCHC 423
C N G+Y C C
Sbjct: 1312 CVNTVGSYHCTC 1323
Score = 86.3 bits (212), Expect = 2e-16
Identities = 60/208 (28%), Positives = 87/208 (41%), Gaps = 36/208 (17%)
Query: 1142 VCNSNPCLHG-GNCEDIYSSYHCSCPLGW----SGKHCELNIDEC--FSNPCIHGNCSDR 1194
+C NP + G G C S Y C+C G+ G C +++DEC PC G C +
Sbjct: 548 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENS 606
Query: 1195 VAAYHCTCEPGYTG----VNCEVDIDNCQS--HQCANGATCISHTNGYSCLCFGNFT--- 1245
++ C C PG+ C +D+D C C G C + + C+C +
Sbjct: 607 PGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAP 664
Query: 1246 -GKFCRQ----SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE 1300
G C+ ++ P +CG G C +C+C GF G CE+D+DE
Sbjct: 665 HGASCQDVDECTQSPG-LCGR----------GACKNLPGSFRCVCPAGFRGSACEEDVDE 713
Query: 1301 CASDPCVNG-GLCQDLLNKFQCLCDVAF 1327
CA +P G G C + F C C F
Sbjct: 714 CAQEPPPCGPGRCDNTAGSFHCACPAGF 741
Score = 86.3 bits (212), Expect = 2e-16
Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 60/246 (24%)
Query: 1152 GNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNP--CIHGNCSDRVAAYHCTC--- 1202
G C++ S+HC+CP G+ G C+ ++DEC +P C +G C + ++ C C
Sbjct: 724 GRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMG 782
Query: 1203 -EPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF-------------------- 1241
+P G CE D+D C++H G C++ + C
Sbjct: 783 FQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 841
Query: 1242 --------------GNFTGKFCRQSRLPST---VCGNEKTNLT---CYNGGNCTEFQTEL 1281
G+F R PS C + L C+ G C
Sbjct: 842 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 901
Query: 1282 KCMCRPGFT----GEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLA 1337
C C PG+ G C D+DEC+ + G+C + F+C+C G R DLA
Sbjct: 902 ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICP---PGHRAGPDLA 957
Query: 1338 DDLISD 1343
L D
Sbjct: 958 SCLDVD 963
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/222 (30%), Positives = 91/222 (40%), Gaps = 34/222 (15%)
Query: 1135 TGCLQLNVCNS--NPCLHGGNCEDIYSSYHCSCPLGWSG----KHCELNIDECFS--NPC 1186
T C+ ++ C PC G CE+ S+ C C G+ C L++DEC PC
Sbjct: 583 TRCIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPC 640
Query: 1187 IHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLC 1240
G C + ++ C C GY G +C+ D+D C C GA C + + C+C
Sbjct: 641 DLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVC 698
Query: 1241 FGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEK 1296
F G C + C E G C C C GF G C+
Sbjct: 699 PAGFRGSACEED---VDECAQEPPPC---GPGRCDNTAGSFHCACPAGFRSRGPGAPCQ- 751
Query: 1297 DIDECA-SDPCVNGGLCQDLLNKFQCLCDVAF----AGERCE 1333
D+DECA S P G C++ FQC+C + F AG CE
Sbjct: 752 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 793
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/257 (26%), Positives = 107/257 (41%), Gaps = 66/257 (25%)
Query: 1137 CLQLNVCNSN--PCLHGGNCEDIYSSYHCSCPLGW---SGKHCEL-NIDECFSNP-CI-H 1188
C ++ C+S PC G+C + S+ CSC G+ SG+ +++EC C H
Sbjct: 832 CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 891
Query: 1189 GNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCF-GN 1243
G C + ++ CTC PGY G +C +D+D C C + + C+C G+
Sbjct: 892 GECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGH 950
Query: 1244 FTGKF---------CRQSRLPSTVCGNEKTNL---------------------TCYNGGN 1273
G CR+ R P+ +CG+++ TC +
Sbjct: 951 RAGPDLASCLDVDECRE-RGPA-LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 1008
Query: 1274 CTEFQTEL-------------KCM--CRPGFT---GEWCEKDIDECASDP-CVNGGLCQD 1314
C E+ E+ +C C PG+ G C+ D+DEC + C +CQ+
Sbjct: 1009 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQN 1067
Query: 1315 LLNKFQCLCDVAFAGER 1331
L FQCLCD + G R
Sbjct: 1068 LPGSFQCLCDQGYEGAR 1084
Score = 77.4 bits (189), Expect = 9e-14
Identities = 108/403 (26%), Positives = 144/403 (35%), Gaps = 95/403 (23%)
Query: 136 CPAGY--AGRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
CP G+ CE D DECA+ CQ+G C + GY+C C G+ D C S
Sbjct: 344 CPTGFERVNGSCE-DVDECATGGRCQHGE-CANTRGGYTCVCPDGFL---LDSSRSSCIS 398
Query: 193 DPCKNEAT--CLNEIGRYTCICP---HNYSGVNCELEIDECWSQPCLNGATCQDALGAYF 247
+EA C + C P + + C + + W + C
Sbjct: 399 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI 458
Query: 248 CDCAPGFLGDHCEL--NTDECASQP---CLHGGLCVDGENRYSCNCTGSGFTGTHC---- 298
C PG+ +L NT +P L + +R S +GF TH
Sbjct: 459 CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPS-----AGFLPTHRLEPR 513
Query: 299 -----------ETLMPL--CWSKP-----------CHNN------ATCEDSVDNYTCHCW 328
E +P W+ P C N C YTC C
Sbjct: 514 PEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACD 573
Query: 329 PGYT----GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
G+ G +C ID++EC P C GR P SF C+
Sbjct: 574 SGFRLSPQGTRC-IDVDECRRVP----PPCAP-------GRCENSPGSFR--------CV 613
Query: 385 CQPGF-TGIHCEE--DVNECSS--NPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 439
C PGF G E DV+EC PC G CEN PG++ C CP + G C
Sbjct: 614 CGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPH--GASCQ 670
Query: 440 DILLGCTHQQCL-NNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
D+ CT L G C ++ F C+CP+G+ GS CE
Sbjct: 671 DVD-ECTQSPGLCGRGAC----KNLPGSFRCVCPAGFRGSACE 708
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/169 (29%), Positives = 71/169 (42%), Gaps = 19/169 (11%)
Query: 1181 CFSNP--CIHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQS--HQCANGATCISH 1232
C NP C G C R + Y C C+ G+ G C +D+D C+ CA G C +
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENS 606
Query: 1233 TNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT-- 1290
+ C+C F L C + C + G C C+C G+
Sbjct: 607 PGSFRCVCGPGFRAGPRAAECLDVDEC--HRVPPPC-DLGRCENTPGSFLCVCPAGYQAA 663
Query: 1291 --GEWCEKDIDECASDPCVNG-GLCQDLLNKFQCLCDVAFAGERCEVDL 1336
G C+ D+DEC P + G G C++L F+C+C F G CE D+
Sbjct: 664 PHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV 711
Score = 64.3 bits (155), Expect = 8e-10
Identities = 61/208 (29%), Positives = 83/208 (39%), Gaps = 36/208 (17%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCS-------DTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + C + +C C D A+ LD D + P GS C
Sbjct: 924 CSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALC----GSQRCE 979
Query: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGK-NSCQHGGI-------CHQDPIYPVCI--C 136
N+PG + C PGY G+C + CQ G C P C C
Sbjct: 980 NSPGSYRCVRDCDPGYHAG----PEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPAC 1035
Query: 137 PAGYA---GRFCEIDHDECAS-SPCQNGAVCQDGIDGYSCFCVPGYQ----GRHCDLEVD 188
GY G C+ D DEC + S C AVCQ+ + C C GY+ GRHC ++V+
Sbjct: 1036 DPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVN 1093
Query: 189 ECAS-DPCKNEATCLNEIGRYTCICPHN 215
EC + A C N G + C+CP++
Sbjct: 1094 ECETLQGVCGAALCENVEGSFLCVCPNS 1121
Score = 64.3 bits (155), Expect = 8e-10
Identities = 76/313 (24%), Positives = 104/313 (33%), Gaps = 64/313 (20%)
Query: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERS 93
C + C+N + D T +D D ++ F C A C N PG S
Sbjct: 1017 CGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSF---CGAHAVCQNLPG--S 1071
Query: 94 FLCKCPPGYSGTI----------CETTIGSCGKNSCQHGG-----ICHQ-----DPIYPV 133
F C C GY G CET G CG C++ +C DP+
Sbjct: 1072 FQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGR 1131
Query: 134 CICPAGYAGRFCEIDHDECAS----------------SPCQNGAVCQDGIDGYSCFCVP- 176
C+ P AG F AS S + G V + Y P
Sbjct: 1132 CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPD 1191
Query: 177 --------GYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYS------GVNCE 222
+ C V E C+ + E Y +CPH ++
Sbjct: 1192 ACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR 1251
Query: 223 LEIDECW---SQPCLNGATCQDALGAYFCDCAPGFLGDHCEL---NTDECASQ-PCLHGG 275
++DEC Q C +G C + Y C C+ G+ L + DECA + P GG
Sbjct: 1252 RDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGG 1310
Query: 276 LCVDGENRYSCNC 288
CV+ Y C C
Sbjct: 1311 RCVNTVGSYHCTC 1323
Score = 47.4 bits (111), Expect = 1e-04
Identities = 71/283 (25%), Positives = 98/283 (34%), Gaps = 75/283 (26%)
Query: 39 CQNNSTCKDFSKDNDCSCS-------DTANNLD-KDCDNMKDPCFSNPCQGSATCVNTPG 90
C ++ C++ C C D + +D +C+ ++ C G+A C N G
Sbjct: 1059 CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVC------GAALCENVEG 1112
Query: 91 ERSFLCKCPPGYSGTICETTIGSCGKNSCQHG---GICHQDPIYPVCIC----------- 136
SFLC CP S + G C G G Q P PV
Sbjct: 1113 --SFLCVCPN--SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRP 1168
Query: 137 ------PAGYAGRFCEIDH---DECASSPCQN--------------GAVCQ----DGIDG 169
P G R C D D C + +N G+ C+ G +
Sbjct: 1169 STPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTET 1228
Query: 170 --YSCFCVPG--YQGRHCDL----EVDECA---SDPCKNEATCLNEIGRYTCICPHNYSG 218
Y C G Y DL +VDEC CK+ C+N Y+C C + Y
Sbjct: 1229 AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS-GVCVNTAPGYSCYCSNGYYY 1287
Query: 219 VNCELEI---DECWSQ-PCLNGATCQDALGAYFCDCAPGFLGD 257
LE DEC + P G C + +G+Y C C P + D
Sbjct: 1288 HTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1330
Score = 39.3 bits (90), Expect = 0.027
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 885 CAGDNSCKSNPCHNG-GVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHG-AQCQP 941
C + C +P G G C + F C CPA G ACEE V C P P G +C
Sbjct: 669 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDN 728
Query: 942 VLQGFECIANAVFNGQ 957
F C A F +
Sbjct: 729 TAGSFHCACPAGFRSR 744
Score = 38.9 bits (89), Expect = 0.035
Identities = 29/125 (23%), Positives = 44/125 (35%), Gaps = 12/125 (9%)
Query: 1172 KHCELNIDECFSNPCIHGNC-SDRVAAYHCTCEPG--YTGVNCEV----DIDNCQ--SHQ 1222
+ C + E + + C C A Y C G Y + ++ D+D CQ Q
Sbjct: 1204 QECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1263
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELK 1282
C++ GYSC C + R + + C +E+ GG C
Sbjct: 1264 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE---PACEGGRCVNTVGSYH 1320
Query: 1283 CMCRP 1287
C C P
Sbjct: 1321 CTCEP 1325
Score = 38.9 bits (89), Expect = 0.035
Identities = 37/129 (28%), Positives = 46/129 (35%), Gaps = 20/129 (15%)
Query: 119 CQHGGICHQDPIYPVCICPAGY---AGRFCEIDHDECASS-PCQNGAVCQDGIDGYSCFC 174
C+ G + P Y C C GY R ID+DECA P G C + + Y C C
Sbjct: 1265 CKSGVCVNTAPGYS-CYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Query: 175 VP-----GYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPH-----NYSGVNCELE 224
P G Q R C + D N C E+G +C H + C
Sbjct: 1324 EPPLVLDGSQ-RRCVSNESQSLDD---NLGVCWQEVGA-DLVCSHPRLDRQATYTECCCL 1378
Query: 225 IDECWSQPC 233
E W C
Sbjct: 1379 YGEAWGMDC 1387
Score = 38.9 bits (89), Expect = 0.035
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGN-EKTNLTCYNGGNCTEFQTEL 1281
C NG C+ G++C CF + R + + C E + C N C
Sbjct: 1543 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDGSF 1600
Query: 1282 KCMCRPGF 1289
+C+CRPGF
Sbjct: 1601 RCICRPGF 1608
Score = 38.1 bits (87), Expect = 0.060
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 5/58 (8%)
Query: 1152 GNCEDIYSSYHCSCPLGWSGKHCELNI---DECFSNP--CIHGNCSDRVAAYHCTCEP 1204
G C + Y C C G+ L DEC C G C + V +YHCTCEP
Sbjct: 1268 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1325
Score = 37.0 bits (84), Expect = 0.13
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 11/99 (11%)
Query: 1167 LGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVN--CEVDIDNCQSHQCA 1224
L W C+L + GN S+RV+A C G+ VN CE D+D C +
Sbjct: 317 LAWGVHDCQLCSERL-------GN-SERVSAPDGPCPTGFERVNGSCE-DVDECATGGRC 367
Query: 1225 NGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEK 1263
C + GY+C+C F R S + V K
Sbjct: 368 QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAK 406
Score = 36.2 bits (82), Expect = 0.23
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 13/85 (15%)
Query: 184 DLEVDECAS-DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDEC-----WSQPC 233
+LE +EC D C N C+ +TC C Y + + C ++I+EC S C
Sbjct: 1531 ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1588
Query: 234 LNGATCQDALGAYFCDCAPGFLGDH 258
+N A C + G++ C C PGF H
Sbjct: 1589 VN-ARCLNTDGSFRCICRPGFAPTH 1612
Score = 35.8 bits (81), Expect = 0.30
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 29/89 (32%)
Query: 313 NATCEDSVDNYTCHCWPGY----TGAQCEIDLNECN----SNPCQSNGECVELSSEKQYG 364
N C + +TC C+ GY T C +D+NEC+ ++P N C+
Sbjct: 1545 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTD------ 1597
Query: 365 RITGLPSSFSYHEASGYVCICQPGFTGIH 393
+ CIC+PGF H
Sbjct: 1598 --------------GSFRCICRPGFAPTH 1612
Score = 35.4 bits (80), Expect = 0.39
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 17/73 (23%)
Query: 89 PGERSFLCKCPP-----GYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGR 143
PG R L + PP G + +C C +GG+C + C+CP +AG+
Sbjct: 130 PGGRGLLRRRPPQRAPAGKAPVLCPLI--------CHNGGVCVKPDR---CLCPPDFAGK 178
Query: 144 FCEIDHDECASSP 156
FC++ H A P
Sbjct: 179 FCQL-HSSGARPP 190
Score = 34.7 bits (78), Expect = 0.66
Identities = 36/158 (22%), Positives = 53/158 (33%), Gaps = 28/158 (17%)
Query: 1180 ECFSNPCIHGNCSDRVAA----YHCTCEPGYT-GVNCEVDIDNCQSHQCANGATCISHTN 1234
EC+ + C + +A C C G G C I C + A + H
Sbjct: 1182 ECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGR 1239
Query: 1235 GYSCLCFGNFTGK-------FCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRP 1287
GY G+ + + R S VC N +CY L+C+
Sbjct: 1240 GYLAPS-GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI--- 1295
Query: 1288 GFTGEWCEKDIDECASD-PCVNGGLCQDLLNKFQCLCD 1324
D DECA + P GG C + + + C C+
Sbjct: 1296 ---------DNDECADEEPACEGGRCVNTVGSYHCTCE 1324
Score = 32.3 bits (72), Expect = 3.3
Identities = 12/30 (40%), Positives = 19/30 (63%), Gaps = 3/30 (10%)
Query: 1266 LTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
L C+NGG C + +C+C P F G++C+
Sbjct: 155 LICHNGGVCVKPD---RCLCPPDFAGKFCQ 181
Score = 32.3 bits (72), Expect = 3.3
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 6/66 (9%)
Query: 888 DNSCKSNPCHNGGVCHSRWDDFSCSCPA----LTSGKACEEVQWC-GFSPCPHGAQCQPV 942
D +S P G C + F C CP T+G CE+V C CP G +C
Sbjct: 754 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP-GQECVNS 812
Query: 943 LQGFEC 948
F+C
Sbjct: 813 PGSFQC 818
Score = 32.0 bits (71), Expect = 4.3
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 19/94 (20%)
Query: 1137 CLQLNVC-NSNPCLHGGNCEDIYSSYHCSCP----LGWSGKHC--------ELNIDECFS 1183
C+ + C + P GG C + SYHC+C L S + C + N+ C+
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1353
Query: 1184 NPCIHGNCS----DRVAAY-HCTCEPGYT-GVNC 1211
CS DR A Y C C G G++C
Sbjct: 1354 EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDC 1387
Score = 32.0 bits (71), Expect = 4.3
Identities = 26/118 (22%), Positives = 45/118 (38%), Gaps = 30/118 (25%)
Query: 1115 GFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS---G 1171
G + +P EE L+ ++ GC G C + + C C G+
Sbjct: 1523 GSLAEPYEE--LEAEECGILDGCTN------------GRCVRVPEGFTCRCFDGYRLDMT 1568
Query: 1172 KHCELNIDEC-----FSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCA 1224
+ ++I+EC S C++ C + ++ C C PG+ + Q H CA
Sbjct: 1569 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH--------QPHHCA 1618
Score = 31.6 bits (70), Expect = 5.6
Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 670 CVRKDWC-ESQPCQSRGRCINLWLSYQCDCHRP 701
C+ D C + +P GRC+N SY C C P
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1326
Score = 31.2 bits (69), Expect = 7.3
Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 15/97 (15%)
Query: 102 YSGTICET----TIGSCGKNSCQHGGICHQDPIYPVCICPAGYA---GRFCEIDHDEC-- 152
Y+G++ E CG G C + P C C GY R +D +EC
Sbjct: 1521 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1580
Query: 153 --ASSPCQNGAVCQDGIDGYSCFCVPGY----QGRHC 183
A+SP A C + + C C PG+ Q HC
Sbjct: 1581 AEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 30.8 bits (68), Expect = 9.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 660 SGSSLNVKAGCVRKDWCES--QPCQSRGRCINLWLSYQCDCHRPYEGPN 706
SG L+ + C D C S PC G C N S++C C Y P+
Sbjct: 823 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 870
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 157 bits (398), Expect = 5e-38
Identities = 147/517 (28%), Positives = 215/517 (41%), Gaps = 109/517 (21%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTAN-NLDKDCDNMKDPCFSNPCQGSATC 85
C + + N C N TC + +C+C++ +C+++ + C NP + C
Sbjct: 2211 CVDTDECSIGNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNCEDINE-CAQNPLLCAFRC 2268
Query: 86 VNTPGERSFLCKCPPGYS----GTICETTIGSC--GKNSCQHGGICHQDPIYP-VCICPA 138
+NT G S+ C CP GY+ +C+ + C G + C+ G+ ++ I +CICP
Sbjct: 2269 MNTFG--SYECTCPIGYALREDQKMCKD-LDECAEGLHDCESRGMMCKNLIGTFMCICPP 2325
Query: 139 GYA----GRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECAS 192
G A G C +D +EC + P C+NG C + I Y C C G+Q E +
Sbjct: 2326 GMARRPDGEGC-VDENECRTKPGICENGR-CVNIIGSYRCECNEGFQSSSSGTECLDNRQ 2383
Query: 193 DPC--------------------KNEATC--------------LNEIGRYTCICPHNYSG 218
C K+E C L +Y ICPH
Sbjct: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGY 2443
Query: 219 VNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFL----GDHCELNTDECASQPCL 272
+IDEC P C NG C + +G++ C C G+ G C ++ DEC+ P
Sbjct: 2444 TTDGRDIDECKVMPNLCTNGQ-CINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSPKP 2501
Query: 273 HGGLCVDGENRYSCNCTGSGFT----GTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCW 328
+C + E Y C+C G+ G C+ L C +K + C +++ +TC C
Sbjct: 2502 CNYICKNTEGSYQCSCP-RGYVLQEDGKTCKDLDE-CQTKQHNCQFLCVNTLGGFTCKCP 2559
Query: 329 PGYTGAQCE-IDLNECNSNP--CQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCIC 385
PG+T ID NEC S P C + G C P SFS C C
Sbjct: 2560 PGFTQHHTACIDNNECGSQPSLCGAKGIC------------QNTPGSFS--------CEC 2599
Query: 386 QPGF----TGIHCEEDVNECSSNP-CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440
Q GF TG++CE DV+EC N CQ+G C+N+ G Y C CP + Y C D
Sbjct: 2600 QRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQH--YQWNQCVD 2654
Query: 441 ILLGCTHQQCLNNGTC-IPHFQDGQHGFSCLCPSGYT 476
+C N C + + C CPSG++
Sbjct: 2655 ------ENECSNPNACGSASCYNTLGSYKCACPSGFS 2685
Score = 154 bits (388), Expect = 8e-37
Identities = 155/525 (29%), Positives = 216/525 (41%), Gaps = 104/525 (19%)
Query: 45 CKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY 102
C++ C C+ + +++C ++ + S GS CVNTPG SF C+C GY
Sbjct: 1089 CRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPG--SFECECFEGY 1146
Query: 103 -SGTICETT---IGSCGKNSCQ-HGGICHQDPIYPVCICPAGY---AGRFCEIDHDECAS 154
SG + I C +N GG C C CP G+ R +D +EC+
Sbjct: 1147 ESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSL 1206
Query: 155 SP--CQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECASDPCKNEATCLNEIGRYT 209
S C+NG C + I Y C C PGYQ R ++DEC + C N G Y
Sbjct: 1207 SDNLCRNGK-CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYE 1265
Query: 210 CICPHNYS----GVNCELEIDECWSQPCL-NGATCQDALGAYFCDCAPGFLG-------- 256
C C Y+ G +C +IDEC + P + +G C + G Y C C GF+
Sbjct: 1266 CSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
Query: 257 --DHCELNTDECASQPCLHGGLCVDGENRYSCNC-----TGSGFTG----THCETLMPLC 305
+ C+LN++ C G C + + + C+C G TG CE
Sbjct: 1325 DVNECDLNSNICMF------GECENTKGSFICHCQLGYSVKKGTTGCTDVDECE-----I 1373
Query: 306 WSKPCHNNATCEDSVDNYTCHCWPGY--TGAQCEIDLNECN--SNPCQSNGECVELSSEK 361
+ C +A+C + ++ C C G+ G +C IDL+EC+ ++ C N +CV
Sbjct: 1374 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCV------ 1426
Query: 362 QYGRITGLPSSFSYHEASGYVCICQPGFT--GIHCEEDVNECSS--NPCQNGGTCENLPG 417
+ Y C C GFT G C DV+EC+ N C+N G C N+PG
Sbjct: 1427 --------------NTPGSYRCACSEGFTGDGFTC-SDVDECAENINLCEN-GQCLNVPG 1470
Query: 418 NYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTC--IPHFQDGQHGFSCLCPSGY 475
Y C C + R C DI C+ Q GTC +P F C+C GY
Sbjct: 1471 AYRCECEMGFTPAS--DSRSCQDI-DECSFQNICVFGTCNNLPGM------FHCICDDGY 1521
Query: 476 ----TGSLCEIATTLSFEGDGFLWVKSGSVTTKGSV-CNIALRFQ 515
TG C T + D V V T G CN FQ
Sbjct: 1522 ELDRTGGNC---TDIDECADPINCVNGLCVNTPGRYECNCPPDFQ 1563
Score = 149 bits (375), Expect = 2e-35
Identities = 143/485 (29%), Positives = 202/485 (41%), Gaps = 130/485 (26%)
Query: 72 DPCFSNP--CQGSATCVNTPGERSFLCKCPPGY----SGTICETTIGSCGKNSCQHGGIC 125
D C P CQG C+NT G SF C+CP GY ICE I C H G+C
Sbjct: 1652 DECQELPGLCQGG-NCINTFG--SFQCECPQGYYLSEDTRICED-IDEC----FAHPGVC 1703
Query: 126 HQDPIYPV-----CICPAGY----AGRFCEIDHDECASSPCQNGAVCQD----------- 165
Y CICP Y G C +D + NG C++
Sbjct: 1704 GPGTCYNTLGNYTCICPPEYMQVNGGHNC-MDMRKSFCYRSYNGTTCENELPFNVTKRMC 1762
Query: 166 --------------------GIDGYSCFC--VPGYQ-----GRHCDLEVDECASDP--CK 196
G + C +PG+ G+ D +DEC P C
Sbjct: 1763 CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD--IDECKEIPGICA 1820
Query: 197 NEATCLNEIGRYTCICPHNYSGVN----CELEIDECWSQP--CLNGATCQDALGAYFCDC 250
N C+N+IG + C CP +S + CE +IDEC + C A C ++ G+Y C+C
Sbjct: 1821 N-GVCINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCEC 1878
Query: 251 APGFL---GDHCELNTDECASQP--CLHGGLCVDGENRYSCNCTGSGFTGTHCETL---M 302
A GF C ++ +EC P C HG LCVD + Y C C +GF + +T+ +
Sbjct: 1879 AAGFKLSPNGAC-VDRNECLEIPNVCSHG-LCVDLQGSYQCICH-NGFKASQDQTMCMDV 1935
Query: 303 PLCWSKPCHNNATCEDSVDNYTCHCWPGY--TGAQCEIDLNECNS---NPCQSNGECVEL 357
C PC N TC+++V +Y C C+PG+ T +D++EC+S C+ NG C
Sbjct: 1936 DECERHPC-GNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCR-NGRC--- 1990
Query: 358 SSEKQYGRITGLPSSFSYHEASGYVCICQPGFT----GIHCEEDVNECSSNPCQ-NGGTC 412
++E + C+C G+ G +C D NEC + P + GTC
Sbjct: 1991 -----------------FNEIGSFKCLCNEGYELTPDGKNCI-DTNECVALPGSCSPGTC 2032
Query: 413 ENLPGNYTCHCP--FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCL 470
+NL G++ C CP ++ S +C + C C N GF CL
Sbjct: 2033 QNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNT----------PGGFQCL 2082
Query: 471 CPSGY 475
CP G+
Sbjct: 2083 CPPGF 2087
Score = 145 bits (366), Expect = 3e-34
Identities = 147/531 (27%), Positives = 212/531 (39%), Gaps = 147/531 (27%)
Query: 53 DCSCSDTANNLDKDCDNMKDPCFS--NPCQGSATCVNTPGERSFLCKCPPGY----SGTI 106
+C + N+L C+++ D C + N CQ +A C+N+PG S+ C+C G+ +G
Sbjct: 1834 ECPTGFSYNDLLLVCEDI-DECSNGDNLCQRNADCINSPG--SYRCECAAGFKLSPNGAC 1890
Query: 107 CETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE---IDHDECASSPCQNGAVC 163
+ N C HG Y CIC G+ + +D DEC PC NG C
Sbjct: 1891 VDRNECLEIPNVCSHGLCVDLQGSYQ-CICHNGFKASQDQTMCMDVDECERHPCGNGT-C 1948
Query: 164 QDGIDGYSCFCVPGYQGRHCD--LEVDECAS---DPCKNEATCLNEIGRYTCICPHNYS- 217
++ + Y+C C PG++ H + L++DEC+S C+N C NEIG + C+C Y
Sbjct: 1949 KNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYEL 2007
Query: 218 ---GVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGF--LGDHCELNTDECASQP 270
G NC ++ +EC + P C G TCQ+ G++ C C PG+ ++C ++ +EC P
Sbjct: 2008 TPDGKNC-IDTNECVALPGSCSPG-TCQNLEGSFRCICPPGYEVKSENC-IDINECDEDP 2064
Query: 271 --CLHGG----------LCVDG----ENRYSCNCTGSGFTGTHCE------------TLM 302
CL G LC G +N C T F T+ E T
Sbjct: 2065 NICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA 2124
Query: 303 PLC--------WSKPCH-----------------------------------------NN 313
C W PC +N
Sbjct: 2125 KCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN 2184
Query: 314 ATCEDSVDNYTCHCWPGY----TGAQCEIDLNECN-SNPCQSNGECVELSSEKQYGRITG 368
C ++ ++ C C GY TG +C +D +EC+ NPC NG C T
Sbjct: 2185 GQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPC-GNGTC------------TN 2230
Query: 369 LPSSFSYHEASGYVCICQPGFTG---IHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPF 425
+ SF C C GF ++CE D+NEC+ NP C N G+Y C CP
Sbjct: 2231 VIGSFE--------CNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPI 2281
Query: 426 DNLSRTFYGGRDCSDILLGCTH--QQCLNNGTCIPHFQDGQHGFSCLCPSG 474
R + C D L C C + G + F C+CP G
Sbjct: 2282 GYALRE--DQKMCKD-LDECAEGLHDCESRGMMCKNLIG---TFMCICPPG 2326
Score = 143 bits (361), Expect = 1e-33
Identities = 130/433 (30%), Positives = 177/433 (40%), Gaps = 84/433 (19%)
Query: 28 NKNNTRCLSNSCQNNSTCKDFSKDNDCSCSD--TANNLDKDC-DNMKDPCFSNPCQGSAT 84
++N R C+N C + C C++ +++ +C DN + CF+ Q
Sbjct: 2338 DENECRTKPGICENGR-CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQ--TI 2394
Query: 85 CVNTPGERSFL----CKCPPGYS-GTICETTIGSCG-KNSCQHGGICHQDPIYPVCICPA 138
C R+ + C C G G CE C + Q+ IC P Y
Sbjct: 2395 CQMASSSRNLVTKSECCCDGGRGWGHQCEL----CPLPGTAQYKKICPHGPGYTT----- 2445
Query: 139 GYAGRFCEIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGY----QGRHCDLEVDECAS 192
GR D DEC P C NG C + + + CFC GY G C +++DEC+
Sbjct: 2446 --DGR----DIDECKVMPNLCTNGQ-CINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQ 2497
Query: 193 DPCKNEATCLNEIGRYTCICPHNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFC 248
P C N G Y C CP Y G C+ ++DEC ++ C + LG + C
Sbjct: 2498 SPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTC 2556
Query: 249 DCAPGFLGDHCE-LNTDECASQPCLHG--GLCVDGENRYSCNCTGSGF----TGTHCETL 301
C PGF H ++ +EC SQP L G G+C + +SC C GF TG +CE +
Sbjct: 2557 KCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQ-RGFSLDATGLNCEDV 2615
Query: 302 MPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGA----QCEIDLNEC-NSNPCQSNGECVE 356
+ C + C++ + Y C C GY QC +D NEC N N C S
Sbjct: 2616 DECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQC-VDENECSNPNACGS------ 2666
Query: 357 LSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEE---DVNECSS--NPCQNGGT 411
+ Y+ Y C C GF+ DVNECSS NPC G
Sbjct: 2667 ---------------ASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-- 2709
Query: 412 CENLPGNYTCHCP 424
C N G Y C CP
Sbjct: 2710 CSNTEGGYLCGCP 2722
Score = 142 bits (359), Expect = 2e-33
Identities = 140/473 (29%), Positives = 194/473 (41%), Gaps = 99/473 (20%)
Query: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
C + CL+ C T + + + AN DC ++ D C SNPC + CV
Sbjct: 498 CKHHANLCLNGRCI--PTVSSYRCECNMGYKQDANG---DCIDV-DECTSNPCT-NGDCV 550
Query: 87 NTPGERSFLCKCPPGYSGTICETT---IGSCGKNS--CQHGGICHQDPIYPVCICPAGYA 141
NTPG S+ CKC G+ T + I C +N C++G + D + CIC AG+
Sbjct: 551 NTPG--SYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQ-CICNAGFE 607
Query: 142 ----GRFCEIDHDECASSP-CQNGAVCQDGIDGYSCFCVPGY----QGRHCDLEVDECAS 192
G+ C +DHDEC ++ C NG +C + + C C PG+ GR+C +VDEC +
Sbjct: 608 LTTDGKNC-VDHDECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYCT-DVDECQT 664
Query: 193 DPCKNEATCLNEIGRYTCICPHNYS-GVNCELEIDECWSQPCLNGATCQDALGAYFCDCA 251
C+N G + C CP + G++ + +D C G + +
Sbjct: 665 PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPF----- 719
Query: 252 PGFL--GDHCELNTDECASQPCL---------HGGLCVDGENRYSCNCTGSGFTGTHCET 300
PG + + C N D +PC GLC G T G C
Sbjct: 720 PGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSG-----VGITVDGRDINECAL 774
Query: 301 LMPLCWSKPCHNNATCEDSVDNYTCHCWPGY----TGAQCEIDLNECNSNPCQ-SNGECV 355
+C N CE+ +Y C+C GY +G C ID++EC N NG C
Sbjct: 775 DPDIC------ANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLC- 826
Query: 356 ELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF---TGIHCEEDVNECSSNPCQNGGTC 412
P S+S C C PG+ T ED+NEC SNPC N G C
Sbjct: 827 -----------RNTPGSYS--------CTCPPGYVFRTETETCEDINECESNPCVN-GAC 866
Query: 413 ENLPGNYTCHC-PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 464
N G++ C C P LS T G C D L GTC + QD +
Sbjct: 867 RNNLGSFNCECSPGSKLSST---GLICIDSL----------KGTCWLNIQDSR 906
Score = 137 bits (344), Expect = 9e-32
Identities = 153/543 (28%), Positives = 198/543 (36%), Gaps = 153/543 (28%)
Query: 44 TCKDFSKDNDCSCSDTANNLDK------DCDNMKDPCFSNPCQGSATCVNTPGERSFLCK 97
TC + C C D LD+ D D DP N G CVNTPG + C
Sbjct: 1505 TCNNLPGMFHCICDD-GYELDRTGGNCTDIDECADPI--NCVNG--LCVNTPGR--YECN 1557
Query: 98 CPPGY----SGTIC-ETTIGSC---------GKNSCQH-------------------GGI 124
CPP + +G C + +G+C G SC G
Sbjct: 1558 CPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNP 1617
Query: 125 CHQDPIYPV------CICPAGYAGRFCEI-----DHDECASSP--CQNGAVCQDGIDGYS 171
C P PV +CP G R I D DEC P CQ G C + +
Sbjct: 1618 CETCP--PVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQ 1674
Query: 172 CFCVPGY----QGRHCDLEVDECASDP--CKNEATCLNEIGRYTCICP---------HN- 215
C C GY R C+ ++DEC + P C TC N +G YTCICP HN
Sbjct: 1675 CECPQGYYLSEDTRICE-DIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHNC 1732
Query: 216 -----------YSGVNCELE---------------IDECWSQPCLNGATCQDALGAYFCD 249
Y+G CE E + + W++PC T A C
Sbjct: 1733 MDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICG 1792
Query: 250 CAPGFLGD-HC--ELNTDECASQPCL-HGGLCVDGENRYSCNCTGSGFTGTHCETLMPLC 305
PGF D H ++ DEC P + G+C++ + C C TG L+ +C
Sbjct: 1793 NIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECP----TGFSYNDLLLVC 1848
Query: 306 --------WSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL 357
C NA C +S +Y C C G+ + + C EC+E+
Sbjct: 1849 EDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSP---------NGACVDRNECLEI 1899
Query: 358 SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEE---DVNECSSNPCQNGGTCEN 414
+ +G L S Y CIC GF + DV+EC +PC N GTC+N
Sbjct: 1900 PNVCSHGLCVDLQGS--------YQCICHNGFKASQDQTMCMDVDECERHPCGN-GTCKN 1950
Query: 415 LPGNYTCHC-PFDNLSRTFYGGRDCSDI-LLGCTHQQCLNNGTCIPHFQDGQHGFSCLCP 472
G+Y C C P L+ DC DI Q NG C F CLC
Sbjct: 1951 TVGSYNCLCYPGFELTH----NNDCLDIDECSSFFGQVCRNGRCFNEI----GSFKCLCN 2002
Query: 473 SGY 475
GY
Sbjct: 2003 EGY 2005
Score = 130 bits (327), Expect = 9e-30
Identities = 135/515 (26%), Positives = 211/515 (40%), Gaps = 111/515 (21%)
Query: 30 NNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPC--FSNPCQGSATCVN 87
N RC S C ++ CS N C K P + +PC+
Sbjct: 2092 NGRRCFDT---RQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCE----LCP 2144
Query: 88 TPGERSFLCKCPPGYSGTI-----CETTIGSCGKNS--CQHGGICHQDPIYPVCICPAGY 140
E +F CP G+ GT+ + C ++ C +G + D + C CP GY
Sbjct: 2145 KDDEVAFQDLCPYGH-GTVPSLHDTREDVNECLESPGICSNGQCINTDGSFR-CECPMGY 2202
Query: 141 ----AGRFCEIDHDECA-SSPCQNGAVCQDGIDGYSCFCVPGYQG---RHCDLEVDECAS 192
G C +D DEC+ +PC NG C + I + C C G++ +C+ +++ECA
Sbjct: 2203 NLDYTGVRC-VDTDECSIGNPCGNGT-CTNVIGSFECNCNEGFEPGPMMNCE-DINECAQ 2259
Query: 193 DPCKNEATCLNEIGRYTCICPHNYS----GVNCELEIDECWS--QPCLN-GATCQDALGA 245
+P C+N G Y C CP Y+ C+ ++DEC C + G C++ +G
Sbjct: 2260 NPLLCAFRCMNTFGSYECTCPIGYALREDQKMCK-DLDECAEGLHDCESRGMMCKNLIGT 2318
Query: 246 YFCDCAPGFL----GDHCELNTDECASQPCL-HGGLCVDGENRYSCNCTG---SGFTGTH 297
+ C C PG G+ C ++ +EC ++P + G CV+ Y C C S +GT
Sbjct: 2319 FMCICPPGMARRPDGEGC-VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTE 2377
Query: 298 C-ETLMPLCWSKP----CHNNATCEDSVDNYTCHCWPGYT-GAQCEI------------- 338
C + LC+++ C ++ + V C C G G QCE+
Sbjct: 2378 CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKIC 2437
Query: 339 -----------DLNECNSNP--CQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCIC 385
D++EC P C +NG+C+ + + C C
Sbjct: 2438 PHGPGYTTDGRDIDECKVMPNLC-TNGQCI--------------------NTMGSFRCFC 2476
Query: 386 QPGFT----GIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDI 441
+ G+T G C D++ECS +P C+N G+Y C CP + + G+ C D
Sbjct: 2477 KVGYTTDISGTSCI-DLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQE--DGKTCKD- 2532
Query: 442 LLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYT 476
L C +Q C+ + GF+C CP G+T
Sbjct: 2533 LDECQTKQHNCQFLCV----NTLGGFTCKCPPGFT 2563
Score = 118 bits (296), Expect = 3e-26
Identities = 97/321 (30%), Positives = 142/321 (44%), Gaps = 43/321 (13%)
Query: 65 KDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGY----SGTICETTIGSCGKNSCQ 120
+D D K N C + C+NT G SF C C GY SGT C + C ++
Sbjct: 2448 RDIDECK--VMPNLCT-NGQCINTMG--SFRCFCKVGYTTDISGTSC-IDLDECSQSPKP 2501
Query: 121 HGGICHQDPIYPVCICPAGYA----GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVP 176
IC C CP GY G+ C+ D DEC + +C + + G++C C P
Sbjct: 2502 CNYICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCKCPP 2560
Query: 177 GYQGRHCD-LEVDECASDP--CKNEATCLNEIGRYTCICPHNYS----GVNCELEIDEC- 228
G+ H ++ +EC S P C + C N G ++C C +S G+NCE ++DEC
Sbjct: 2561 GFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVDECD 2619
Query: 229 WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNT----DECASQPCLHGGLCVDGENRY 284
+ C +G CQ+ LG Y C C G++ H + N +EC++ C + Y
Sbjct: 2620 GNHRCQHG--CQNILGGYRCGCPQGYI-QHYQWNQCVDENECSNPNACGSASCYNTLGSY 2676
Query: 285 SCNCTGSGFT----GTHCETLMPLCWSK-PCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339
C C SGF+ + C + SK PC N C ++ Y C C PGY +
Sbjct: 2677 KCACP-SGFSFDQFSSACHDVNECSSSKNPC--NYGCSNTEGGYLCGCPPGY----YRVG 2729
Query: 340 LNECNSNPCQSNGECVELSSE 360
C S + G+ + L +E
Sbjct: 2730 QGHCVSGMGFNKGQYLSLDTE 2750
Score = 110 bits (275), Expect = 1e-23
Identities = 138/523 (26%), Positives = 189/523 (36%), Gaps = 164/523 (31%)
Query: 79 CQGSATCVN---TPGERSFLCKCPPGYS----GTIC------ETTIGSCGKNSCQH---G 122
CQ C+N E SF C CPPG + G +C T G K C G
Sbjct: 662 CQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPG 721
Query: 123 GI-----CHQDPIY----PVCICPAGYAGRFCEI------------DHDECASSP--CQN 159
+ C +P Y P CPA + F + D +ECA P C N
Sbjct: 722 AVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICAN 781
Query: 160 GAVCQDGIDGYSCFCVPGYQ----GRHCDLEVDECASDP--CKNEATCLNEIGRYTCICP 213
G +C++ Y C C GY+ GR+C +++DEC + C N C N G Y+C CP
Sbjct: 782 G-ICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDN-GLCRNTPGSYSCTCP 838
Query: 214 HNY----SGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQ 269
Y CE +I+EC S PC+NGA C++ LG++ C+C+PG S+
Sbjct: 839 PGYVFRTETETCE-DINECESNPCVNGA-CRNNLGSFNCECSPG--------------SK 882
Query: 270 PCLHGGLCVDG----------ENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319
G +C+D ++R N G+ C TL W PC CE
Sbjct: 883 LSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATL-GAAWGSPCER---CE-- 936
Query: 320 VDNYTCHCWPGYTGAQCEIDLNECNSNP--CQSNGECV---------------------- 355
+D G CE D+NEC P C NG CV
Sbjct: 937 LDTACPRGLARIKGVTCE-DVNECEVFPGVCP-NGRCVNSKGSFHCECPEGLTLDGTGRV 994
Query: 356 --ELSSEKQYGR------ITGLPSSFSYHEASGYVCICQPGFT-GIHCEE---------- 396
++ E+ Y + I +P F C C G G CEE
Sbjct: 995 CLDIRMEQCYLKWDEDECIHPVPGKFRMD-----ACCCAVGAAWGTECEECPKPGTKEYE 1049
Query: 397 -----------------------DVNECSSNPCQ-NGGTCENLPGNYTCHCPFDNLSRTF 432
D+NEC + P G C N G++ C C ++
Sbjct: 1050 TLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRC--NSGFALD 1107
Query: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGY 475
R+C+DI +G C+ + F C C GY
Sbjct: 1108 MEERNCTDIDECRISPDLCGSGICV----NTPGSFECECFEGY 1146
Score = 105 bits (262), Expect = 3e-22
Identities = 147/570 (25%), Positives = 211/570 (37%), Gaps = 161/570 (28%)
Query: 24 NSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCS--CSDTANNLDKDCDNMK--------DP 73
+ FC++ N C +S Q +STC S CS C + D C K P
Sbjct: 121 DGFCSRPNM-CTCSSGQISSTCGSKSIQQ-CSVRCMNGGTCADDHCQCQKGYIGTYCGQP 178
Query: 74 CFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTI--GSC----GKNSCQH---GGI 124
N CQ C+ P C C G++G CE G C CQ G +
Sbjct: 179 VCENGCQNGGRCIG-PNR----CACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIV 233
Query: 125 CHQDPI---------YPVCICPA-------GYAGRF----CEIDHDECASSP--CQNGAV 162
C + +P +CPA G+ C+ D DEC + P CQ G
Sbjct: 234 CTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGN- 291
Query: 163 CQDGIDGYSCFCVPGYQG----RHCDLEVDECASDP--CKNEATCLNEIGRYTCICPHNY 216
C + + + C C G++ + C+ ++DEC+ P C+ C N +G Y C+CP Y
Sbjct: 292 CINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICET-GECSNTVGSYFCVCPRGY 349
Query: 217 ----SGVNC-ELEIDECWSQPCLNGATCQDALGAYF---CDCAP------GFLGDHCELN 262
G C + C+S +NG Q+ G C C P G + + C +
Sbjct: 350 VTSTDGSRCIDQRTGMCFS-GLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVR 408
Query: 263 TDECASQPCLH-------------------------------------GGLCVDGENRYS 285
E + C+ G + + G N +S
Sbjct: 409 GSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFS 468
Query: 286 CNCTGSG---------FTG-THCETLMPLC--WSKPCHNNATCEDSVDNYTCHCWPGY-- 331
G+G TG T + +C + C N C +V +Y C C GY
Sbjct: 469 PGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLC-LNGRCIPTVSSYRCECNMGYKQ 527
Query: 332 -TGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFT 390
C ID++EC SNPC +NG+CV + Y C C GF
Sbjct: 528 DANGDC-IDVDECTSNPC-TNGDCV--------------------NTPGSYYCKCHAGFQ 565
Query: 391 GIHCEE---DVNECSSNP--CQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGC 445
++ D++EC N C+N G C N G++ C C T G++C D
Sbjct: 566 RTPTKQACIDIDECIQNGVLCKN-GRCVNTDGSFQCICNAGFELTT--DGKNCVDHDECT 622
Query: 446 THQQCLNNGTCIPHFQDGQHGFSCLCPSGY 475
T CL NG CI +DG F C+C G+
Sbjct: 623 TTNMCL-NGMCIN--EDG--SFKCICKPGF 647
Score = 104 bits (259), Expect = 7e-22
Identities = 79/234 (33%), Positives = 104/234 (44%), Gaps = 32/234 (13%)
Query: 42 NSTCKDFSKDNDCSCSD--TANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSFLCKCP 99
N CK+ CSC K C ++ D C + CVNT G F CKCP
Sbjct: 2503 NYICKNTEGSYQCSCPRGYVLQEDGKTCKDL-DECQTKQHNCQFLCVNTLG--GFTCKCP 2559
Query: 100 PGYSG--TICETTIGSCGKNS--CQHGGICHQDPIYPVCICPAGYA----GRFCEIDHDE 151
PG++ T C CG C GIC P C C G++ G CE D DE
Sbjct: 2560 PGFTQHHTACIDN-NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCE-DVDE 2617
Query: 152 C-ASSPCQNGAVCQDGIDGYSCFCVPGY----QGRHCDLEVDECASDPCKNEATCLNEIG 206
C + CQ+G CQ+ + GY C C GY Q C ++ +EC++ A+C N +G
Sbjct: 2618 CDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQC-VDENECSNPNACGSASCYNTLG 2674
Query: 207 RYTCICPHNYS----GVNCELEIDECWSQ--PCLNGATCQDALGAYFCDCAPGF 254
Y C CP +S C +++EC S PC G C + G Y C C PG+
Sbjct: 2675 SYKCACPSGFSFDQFSSACH-DVNECSSSKNPCNYG--CSNTEGGYLCGCPPGY 2725
Score = 102 bits (254), Expect = 3e-21
Identities = 69/211 (32%), Positives = 99/211 (46%), Gaps = 24/211 (11%)
Query: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCEL---NIDEC---FSNPCIH 1188
C+ +N C NSN C+ G CE+ S+ C C LG+S K ++DEC N +H
Sbjct: 1323 CIDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMH 1381
Query: 1189 GNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQS--HQCANGATCISHTNGYSCLCFGNF 1244
+C + ++ C+C G+ G+ C +D+D C + HQC+ A C++ Y C C F
Sbjct: 1382 ASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF 1440
Query: 1245 TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDE 1300
TG S + E NL C N G C +C C GFT C+ DIDE
Sbjct: 1441 TGDGFTCSDVDECA---ENINL-CEN-GQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDE 1494
Query: 1301 CASDPCVNGGLCQDLLNKFQCLCDVAFAGER 1331
C+ G C +L F C+CD + +R
Sbjct: 1495 CSFQNICVFGTCNNLPGMFHCICDDGYELDR 1525
Score = 102 bits (253), Expect = 3e-21
Identities = 136/532 (25%), Positives = 189/532 (35%), Gaps = 123/532 (23%)
Query: 33 RCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGER 92
+C+ C+N+ S+ N C+CS + + C + S C TC +
Sbjct: 109 QCIVPICRNSCGDGFCSRPNMCTCS--SGQISSTCGSKSIQQCSVRCMNGGTCADDH--- 163
Query: 93 SFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYP-VCICPAGYAGRFCEIDHDE 151
C+C GY GT C + C +N CQ+GG C I P C C G+ G CE D+
Sbjct: 164 ---CQCQKGYIGTYCGQPV--C-ENGCQNGGRC----IGPNRCACVYGFTGPQCERDY-- 211
Query: 152 CASSPC---QNGAVCQDGIDG------YSCFCVPGYQGRHCDL----------------- 185
+ PC N +CQ + G C + G C++
Sbjct: 212 -RTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIR 270
Query: 186 -----EVDECASDP--CKNEATCLNEIGRYTCICP--HNYSGV--NCELEIDECWSQP-- 232
+VDEC + P C+ C+N +G + C CP H S CE +IDEC P
Sbjct: 271 TGACQDVDECQAIPGICQG-GNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGI 328
Query: 233 CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
C G C + +G+YFC C G++ + C Q G+C G C G
Sbjct: 329 CETG-ECSNTVGSYFCVCPRGYV---TSTDGSRCIDQ---RTGMCFSGLVNGRCAQELPG 381
Query: 293 -FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCW---------------PGYTGAQC 336
T C CW A + Y C PG TG
Sbjct: 382 RMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNG 441
Query: 337 EIDLNECN--------------SNPCQSNGECVELSSEKQYGRITGLP---SSFSYHEAS 379
N N + + Q ITGL + +
Sbjct: 442 FAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHH 501
Query: 380 GYVCI---CQPGFTGIHCE------EDVN-------ECSSNPCQNGGTCENLPGNYTCHC 423
+C+ C P + CE +D N EC+SNPC N G C N PG+Y C C
Sbjct: 502 ANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTN-GDCVNTPGSYYCKC 560
Query: 424 PFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGY 475
RT + C DI + NG C+ DG F C+C +G+
Sbjct: 561 -HAGFQRT-PTKQACIDIDECIQNGVLCKNGRCVN--TDG--SFQCICNAGF 606
Score = 101 bits (252), Expect = 4e-21
Identities = 74/228 (32%), Positives = 103/228 (45%), Gaps = 36/228 (15%)
Query: 1127 KISTNSVVTGCLQLNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCE---LNIDEC 1181
K+S N C+ N C P C HG C D+ SY C C G+ + +++DEC
Sbjct: 1883 KLSPNGA---CVDRNECLEIPNVCSHG-LCVDLQGSYQCICHNGFKASQDQTMCMDVDEC 1938
Query: 1182 FSNPCIHGNCSDRVAAYHCTCEPGY--TGVNCEVDIDNCQS---HQCANGATCISHTNGY 1236
+PC +G C + V +Y+C C PG+ T N +DID C S C NG C + +
Sbjct: 1939 ERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNG-RCFNEIGSF 1997
Query: 1237 SCLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF--T 1290
CLC + GK C + + G+ + G C + +C+C PG+
Sbjct: 1998 KCLCNEGYELTPDGKNCIDTNECVALPGS-------CSPGTCQNLEGSFRCICPPGYEVK 2050
Query: 1291 GEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAFA----GERC 1332
E C DI+EC DP C+ G C + FQCLC F G RC
Sbjct: 2051 SENC-IDINECDEDPNICLFGS-CTNTPGGFQCLCPPGFVLSDNGRRC 2096
Score = 100 bits (248), Expect = 1e-20
Identities = 69/219 (31%), Positives = 101/219 (46%), Gaps = 36/219 (16%)
Query: 1133 VVTGCLQLN----VC--NSNPCLHGGNCEDIYSSYHCSCPLGW---SGKHCELNIDECFS 1183
++TG LN +C ++N CL+G C SSY C C +G+ + C +++DEC S
Sbjct: 484 IITGLTILNQTIDICKHHANLCLNG-RCIPTVSSYRCECNMGYKQDANGDC-IDVDECTS 541
Query: 1184 NPCIHGNCSDRVAAYHCTCEPGY----TGVNCEVDIDNCQSH--QCANGATCISHTNGYS 1237
NPC +G+C + +Y+C C G+ T C +DID C + C NG C++ +
Sbjct: 542 NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNG-RCVNTDGSFQ 599
Query: 1238 CLCFGNF----TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF---- 1289
C+C F GK C V +E T G C KC+C+PGF
Sbjct: 600 CICNAGFELTTDGKNC--------VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAP 651
Query: 1290 TGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFA 1328
G +C D+DEC + G C + F+C C A
Sbjct: 652 NGRYC-TDVDECQTPGICMNGHCINSEGSFRCDCPPGLA 689
Score = 93.6 bits (231), Expect = 1e-18
Identities = 62/212 (29%), Positives = 92/212 (43%), Gaps = 22/212 (10%)
Query: 1133 VVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECF--SNP 1185
++ C+ ++ C NP L GG C + S+ C CPLG S + C ++I+EC N
Sbjct: 1152 MMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC-VDINECSLSDNL 1210
Query: 1186 CIHGNCSDRVAAYHCTCEPGYTGV----NCEVDIDNCQSHQCANGATCISHTNGYSCLCF 1241
C +G C + + Y C+C PGY C DID C C + Y C C
Sbjct: 1211 CRNGKCVNMIGTYQCSCNPGYQATPDRQGC-TDIDECMIMNGGCDTQCTNSEGSYECSCS 1269
Query: 1242 GNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK---DI 1298
+ +S C N N +GG CT E +C+C GF K D+
Sbjct: 1270 EGYALMPDGRSCADIDECEN---NPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDV 1326
Query: 1299 DEC--ASDPCVNGGLCQDLLNKFQCLCDVAFA 1328
+EC S+ C+ G C++ F C C + ++
Sbjct: 1327 NECDLNSNICMFGE-CENTKGSFICHCQLGYS 1357
Score = 82.0 bits (201), Expect = 4e-15
Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 28/222 (12%)
Query: 1120 PQEEQFLKISTNS--VVTGCLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW----SGK 1172
P Q+ KI + T ++ C P L G C + S+ C C +G+ SG
Sbjct: 2428 PGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGT 2487
Query: 1173 HCELNIDECFSN--PCIHGNCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQCANG 1226
C +++DEC + PC + C + +Y C+C GY G C+ D+D CQ+ Q
Sbjct: 2488 SC-IDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQ 2544
Query: 1227 ATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCR 1286
C++ G++C C FT + + + CG++ + C G C C C+
Sbjct: 2545 FLCVNTLGGFTCKCPPGFTQH--HTACIDNNECGSQPS--LCGAKGICQNTPGSFSCECQ 2600
Query: 1287 PGF----TGEWCEKDIDEC-ASDPCVNGGLCQDLLNKFQCLC 1323
GF TG CE D+DEC + C +G CQ++L ++C C
Sbjct: 2601 RGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGC 2639
Score = 80.9 bits (198), Expect = 8e-15
Identities = 82/287 (28%), Positives = 120/287 (41%), Gaps = 67/287 (23%)
Query: 239 CQDALGAYFCD------CAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292
C+++ G FC C+ G + C + + S C++GG C D C C G
Sbjct: 115 CRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDH----CQCQ-KG 169
Query: 293 FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNG 352
+ GT+C P+C C N C + C C G+TG QCE D + PC
Sbjct: 170 YIGTYCG--QPVC-ENGCQNGGRC---IGPNRCACVYGFTGPQCERDY---RTGPC---- 216
Query: 353 ECVELSSEKQYGRITGLPSS-----FSYHEASGYVC--------ICQPGF-----TGIHC 394
+++++ G++TG+ + + A G+ C C+ GF TG C
Sbjct: 217 -FTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGA-C 274
Query: 395 EEDVNECSSNP--CQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRD---CSDILLGCTHQ 448
+DV+EC + P CQ GG C N G++ C CP + S T D CS I C
Sbjct: 275 -QDVDECQAIPGICQ-GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
Query: 449 QCLNNGTCIPHFQDGQHGFSCLCPSGYT----GSLC-EIATTLSFEG 490
+C N + C+CP GY GS C + T + F G
Sbjct: 333 ECSNT----------VGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG 369
Score = 80.5 bits (197), Expect = 1e-14
Identities = 69/221 (31%), Positives = 98/221 (44%), Gaps = 44/221 (19%)
Query: 1140 LNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP--CIHGNCS 1192
+N C +P + G CE++ SY C+C G+ SG++C ++IDEC N C +G C
Sbjct: 769 INECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCR 827
Query: 1193 DRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFG----NF 1244
+ +Y CTC PGY CE DI+ C+S+ C NGA C ++ ++C C +
Sbjct: 828 NTPGSYSCTCPPGYVFRTETETCE-DINECESNPCVNGA-CRNNLGSFNCECSPGSKLSS 885
Query: 1245 TGKFC------------RQSRLPSTVCGNEKTNLTCYN-----GGNCTEFQTELKCMCRP 1287
TG C + SR + G + C G C + EL C
Sbjct: 886 TGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCE--RCELDTACPR 943
Query: 1288 GFT---GEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLC 1323
G G CE D++EC P C N G C + F C C
Sbjct: 944 GLARIKGVTCE-DVNECEVFPGVCPN-GRCVNSKGSFHCEC 982
Score = 80.5 bits (197), Expect = 1e-14
Identities = 73/236 (30%), Positives = 100/236 (42%), Gaps = 54/236 (22%)
Query: 1137 CLQLNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDEC-FSNPCIHG 1189
C ++ C N N C G C ++ +Y C C +G++ + C+ +IDEC F N C+ G
Sbjct: 1447 CSDVDECAENINLC-ENGQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFG 1504
Query: 1190 NCSDRVAAYHCTCEPGY----TGVNCEVDIDNCQSH-QCANGATCISHTNGYSCLCFGNF 1244
C++ +HC C+ GY TG NC DID C C NG C++ Y C C +F
Sbjct: 1505 TCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNG-LCVNTPGRYECNCPPDF 1562
Query: 1245 ----TGKFCRQSRL------------PSTVCGNE------KTNLTCYNG---GNCTEF-- 1277
TG C +R+ S C E +++ C G GN E
Sbjct: 1563 QLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCP 1622
Query: 1278 ---QTELKCMCRPGFTG------EWCEKDIDECASDP-CVNGGLCQDLLNKFQCLC 1323
TE +C PG G +DIDEC P GG C + FQC C
Sbjct: 1623 PVNSTEYYTLC-PGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCEC 1677
Score = 79.0 bits (193), Expect = 3e-14
Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 18/214 (8%)
Query: 1140 LNVCNSNPCL-HGGNCEDIYSSYHCSCPLGWS----GKHCELNIDEC-FSNPCIHGNCSD 1193
+N C +P + G C + S+ C CP+G++ G C ++ DEC NPC +G C++
Sbjct: 2172 VNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC-VDTDECSIGNPCGNGTCTN 2230
Query: 1194 RVAAYHCTCEPGYTG---VNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
+ ++ C C G+ +NCE DI+ C + C++ Y C C + + +
Sbjct: 2231 VIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQ 2289
Query: 1251 QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFT----GEWCEKDIDECASDPC 1306
+ C E + G C C+C PG GE C D +EC + P
Sbjct: 2290 KMCKDLDECA-EGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPG 2347
Query: 1307 V-NGGLCQDLLNKFQCLCDVAFAGERCEVDLADD 1339
+ G C +++ ++C C+ F + D+
Sbjct: 2348 ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN 2381
Score = 77.8 bits (190), Expect = 7e-14
Identities = 68/238 (28%), Positives = 100/238 (42%), Gaps = 55/238 (23%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS----GKHCELNIDECFSNPCIHG--- 1189
C +N C NP L C + + SY C+CP+G++ K C+ ++DEC +H
Sbjct: 2251 CEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCK-DLDECAEG--LHDCES 2307
Query: 1190 ---NCSDRVAAYHCTCEPGYT----GVNCEVDIDNCQSHQ--CANGATCISHTNGYSCLC 1240
C + + + C C PG G C VD + C++ C NG C++ Y C C
Sbjct: 2308 RGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENG-RCVNIIGSYRCEC 2365
Query: 1241 FGNF----TGKFCRQSR-------LPSTVC--GNEKTNLT-----CYNGGNCTEFQTEL- 1281
F +G C +R + T+C + NL C +GG Q EL
Sbjct: 2366 NEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELC 2425
Query: 1282 ----------KCMCRPGFTGEWCEKDIDECASDP--CVNGGLCQDLLNKFQCLCDVAF 1327
C PG+T + +DIDEC P C N G C + + F+C C V +
Sbjct: 2426 PLPGTAQYKKICPHGPGYTTD--GRDIDECKVMPNLCTN-GQCINTMGSFRCFCKVGY 2480
Score = 77.4 bits (189), Expect = 9e-14
Identities = 63/208 (30%), Positives = 84/208 (40%), Gaps = 38/208 (18%)
Query: 40 QNNSTCKDF----SKDNDCS--CSDTANNLDKDC------------DNMKDPCFSNP--C 79
++ TCKD +K ++C C +T C DN + C S P C
Sbjct: 2525 EDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDN--NECGSQPSLC 2582
Query: 80 QGSATCVNTPGERSFLCKCPPGYS----GTICETTIGSCGKNSCQHGGICHQDPIYPVCI 135
C NTPG SF C+C G+S G CE G + CQHG C C
Sbjct: 2583 GAKGICQNTPG--SFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG--CQNILGGYRCG 2638
Query: 136 CPAGYAGRF----CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGY---QGRHCDLEVD 188
CP GY + C +D +EC++ A C + + Y C C G+ Q +V+
Sbjct: 2639 CPQGYIQHYQWNQC-VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVN 2697
Query: 189 ECASDPCKNEATCLNEIGRYTCICPHNY 216
EC+S C N G Y C CP Y
Sbjct: 2698 ECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
Score = 76.6 bits (187), Expect = 2e-13
Identities = 49/166 (29%), Positives = 74/166 (44%), Gaps = 23/166 (13%)
Query: 1176 LNIDECFSNP--CIHGNCSDRVAAYHCTCEPGYTGVN----CEVDIDNCQS--HQCANGA 1227
++IDEC P C +G C +++ ++ C C G++ + CE DID C + + C A
Sbjct: 1807 VDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNA 1865
Query: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYN---GGNCTEFQTELKCM 1284
CI+ Y C C F P+ C + L N G C + Q +C+
Sbjct: 1866 DCINSPGSYRCECAAGF-------KLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCI 1918
Query: 1285 CRPGFTGEWCE---KDIDECASDPCVNGGLCQDLLNKFQCLCDVAF 1327
C GF + D+DEC PC N G C++ + + CLC F
Sbjct: 1919 CHNGFKASQDQTMCMDVDECERHPCGN-GTCKNTVGSYNCLCYPGF 1963
Score = 75.9 bits (185), Expect = 3e-13
Identities = 62/212 (29%), Positives = 91/212 (42%), Gaps = 45/212 (21%)
Query: 1140 LNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP--CIHGNCS 1192
++ C P L GGNC + + S+ C CP G+ + CE +IDECF++P C G C
Sbjct: 1651 IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGTCY 1709
Query: 1193 DRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQS 1252
+ + Y C C P Y VN G C+ + C+ ++ G C ++
Sbjct: 1710 NTLGNYTCICPPEYMQVN--------------GGHNCMDMRKSF---CYRSYNGTTC-EN 1751
Query: 1253 RLPSTVCGNEKTNLTCYNGGNC---------TEFQTELKCMCR--PGFTGE---WCEKDI 1298
LP V ++ YN G T + K +C PGFT + DI
Sbjct: 1752 ELPFNV--TKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI 1809
Query: 1299 DECASDP--CVNGGLCQDLLNKFQCLCDVAFA 1328
DEC P C N G+C + + F+C C F+
Sbjct: 1810 DECKEIPGICAN-GVCINQIGSFRCECPTGFS 1840
Score = 73.2 bits (178), Expect = 2e-12
Identities = 63/256 (24%), Positives = 103/256 (40%), Gaps = 66/256 (25%)
Query: 1125 FLKISTNSVVTG--CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGW----SGKHCE--- 1175
F K+ + ++G C+ L+ C+ +P C++ SY CSCP G+ GK C+
Sbjct: 2475 FCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLD 2534
Query: 1176 -----------------------------------LNIDECFSNPCI---HGNCSDRVAA 1197
++ +EC S P + G C + +
Sbjct: 2535 ECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGS 2594
Query: 1198 YHCTCEPGY----TGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFTGKFCRQS 1252
+ C C+ G+ TG+NCE D+D C +H+C +G C + GY C C + +
Sbjct: 2595 FSCECQRGFSLDATGLNCE-DVDECDGNHRCQHG--CQNILGGYRCGC----PQGYIQHY 2647
Query: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK---DIDECAS--DPCV 1307
+ V NE +N +C KC C GF+ + D++EC+S +PC
Sbjct: 2648 QWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCN 2707
Query: 1308 NGGLCQDLLNKFQCLC 1323
G C + + C C
Sbjct: 2708 YG--CSNTEGGYLCGC 2721
Score = 69.7 bits (169), Expect = 2e-11
Identities = 59/200 (29%), Positives = 78/200 (39%), Gaps = 31/200 (15%)
Query: 1159 SSYHCSCPLGWSGKHCELNIDEC--FSNPCIHGNCSDRVAAYHCTCEPGYT----GVNCE 1212
+ Y CP G +IDEC N C +G C + + ++ C C+ GYT G +C
Sbjct: 2431 AQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC- 2489
Query: 1213 VDIDNCQSHQCANGATCISHTNGYSCLCFGNFT----GKFCRQSRLPSTVCGNEKTNLTC 1268
+D+D C C + Y C C + GK C+ L C
Sbjct: 2490 IDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD--LDECQTKQHNCQFLC 2547
Query: 1269 YN--GGNCTEFQTELKCMCRPGFTGEWCE-KDIDECASDPCVNG--GLCQDLLNKFQCLC 1323
N GG C C PGFT D +EC S P + G G+CQ+ F C C
Sbjct: 2548 VNTLGG--------FTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCEC 2599
Query: 1324 DVAFA----GERCE-VDLAD 1338
F+ G CE VD D
Sbjct: 2600 QRGFSLDATGLNCEDVDECD 2619
Score = 68.6 bits (166), Expect = 4e-11
Identities = 63/240 (26%), Positives = 98/240 (40%), Gaps = 59/240 (24%)
Query: 1140 LNVCNSNP--CLHGGNCEDIYSSYHCSCPLGWSGKHCELN---IDECFSNP--CIHGNCS 1192
+N C + P C +G C + S+ C C G++ E N IDEC +P C G C
Sbjct: 1074 INECKAFPGMCTYG-KCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1132
Query: 1193 DRVAAYHCTCEPGYTG-----VNCEVDIDNCQSHQ-CANGATCISHTNGYSCLC-FG--- 1242
+ ++ C C GY NC +DID C+ + G TC++ + C C G
Sbjct: 1133 NTPGSFECECFEGYESGFMMMKNC-MDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHEL 1191
Query: 1243 -------------NFTGKFCRQSRLPSTV----C----GNEKT----------NLTCYNG 1271
+ + CR + + + C G + T NG
Sbjct: 1192 SPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG 1251
Query: 1272 G---NCTEFQTELKCMCRPGFT----GEWCEKDIDECASDPCV-NGGLCQDLLNKFQCLC 1323
G CT + +C C G+ G C DIDEC ++P + +GG C ++ +++CLC
Sbjct: 1252 GCDTQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICDGGQCTNIPGEYRCLC 1310
Score = 67.0 bits (162), Expect = 1e-10
Identities = 58/216 (26%), Positives = 81/216 (37%), Gaps = 41/216 (18%)
Query: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYT 1207
C++GG C D HC C G+ G +C + E N C +G + C C G+T
Sbjct: 153 CMNGGTCADD----HCQCQKGYIGTYCGQPVCE---NGCQNGGRC--IGPNRCACVYGFT 203
Query: 1208 GVNCEVD------IDNCQSHQCANGATCISHTNGYSCLCFGNFTG----------KFCRQ 1251
G CE D + C T I T C G G + CR+
Sbjct: 204 GPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRR 263
Query: 1252 SRLPSTVCGNEKTNLTCY------NGGNCTEFQTELKCMCRPGF----TGEWCEKDIDEC 1301
+P+ G + C GGNC +C C G T + CE DIDEC
Sbjct: 264 GFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE-DIDEC 322
Query: 1302 ASDPCV-NGGLCQDLLNKFQCLCDVAFA----GERC 1332
+ P + G C + + + C+C + G RC
Sbjct: 323 SIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 358
Score = 65.5 bits (158), Expect = 4e-10
Identities = 55/220 (25%), Positives = 88/220 (40%), Gaps = 28/220 (12%)
Query: 1137 CLQLNVCN-SNPCLHGGNCEDIYSSYHCSCPLGWSG---KHCELNIDECFSNPCIHG-NC 1191
C+ + C+ NPC G C ++ S+ C+C G+ +CE +I+EC NP + C
Sbjct: 2211 CVDTDECSIGNPC-GNGTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRC 2268
Query: 1192 SDRVAAYHCTCEPGYT----GVNCEVDIDNCQS--HQC-ANGATCISHTNGYSCLCFGNF 1244
+ +Y CTC GY C+ D+D C H C + G C + + C+C
Sbjct: 2269 MNTFGSYECTCPIGYALREDQKMCK-DLDECAEGLHDCESRGMMCKNLIGTFMCICPPGM 2327
Query: 1245 TGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGF----TGEWCEKD--- 1297
+ + + C +T G C +C C GF +G C +
Sbjct: 2328 ARRPDGEGCVDENEC---RTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQG 2384
Query: 1298 --IDECASDPCVNGGLCQDLLNKFQCLCDVAFA-GERCEV 1334
E C ++L+ K +C CD G +CE+
Sbjct: 2385 LCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCEL 2424
Score = 58.9 bits (141), Expect = 3e-08
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 46/159 (28%)
Query: 1137 CLQLNVCNSNPCL-HGGNCEDIYSSYHCSCPLGW----SGKHCELNIDECFSNP--CIHG 1189
C ++ C + P + GGNC + S+ C CP G + + CE +IDEC P C G
Sbjct: 274 CQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETG 332
Query: 1190 NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFC 1249
CS+ V +Y C C GY +G+ CI G +CF C
Sbjct: 333 ECSNTVGSYFCVCPRGYV--------------TSTDGSRCIDQRTG---MCFSGLVNGRC 375
Query: 1250 RQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPG 1288
Q LP + T+++C C PG
Sbjct: 376 AQ-ELPGRM--------------------TKMQCCCEPG 393
Score = 55.5 bits (132), Expect = 4e-07
Identities = 59/203 (29%), Positives = 81/203 (39%), Gaps = 36/203 (17%)
Query: 1159 SSYHCSCPLGWSGKHCELNIDECFSNP--CIHGNCSDRVAAYHCTCEPGY----TGVNCE 1212
+ +H C G +I+EC +P C +G C + +Y C C GY +G NC
Sbjct: 750 AEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC- 808
Query: 1213 VDIDNCQSHQ--CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG--NEKTNLTC 1268
+DID C ++ C NG C + YSC C + R + C NE + C
Sbjct: 809 IDIDECLVNRLLCDNG-LCRNTPGSYSCTCPPGYV------FRTETETCEDINECESNPC 861
Query: 1269 YNGGNCTEFQTELKCMCRPG----FTGEWCEKDIDECASDPCVN--GGLCQDLLN----K 1318
NG C C C PG TG C ID +N C+ +N K
Sbjct: 862 VNGA-CRNNLGSFNCECSPGSKLSSTGLIC---IDSLKGTCWLNIQDSRCEVNINGATLK 917
Query: 1319 FQCLCDVAFAG----ERCEVDLA 1337
+C + A ERCE+D A
Sbjct: 918 SECCATLGAAWGSPCERCELDTA 940
Score = 52.0 bits (123), Expect = 4e-06
Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 38/147 (25%)
Query: 1198 YHCTCEPGYT----GVNCEVDI--DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
+H C PG+ G C V I ++C C+ C C
Sbjct: 93 FHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCT------------------CSS 134
Query: 1252 SRLPSTVCGN---EKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
++ ST CG+ ++ ++ C NGG C + C C+ G+ G +C + + E + C N
Sbjct: 135 GQISST-CGSKSIQQCSVRCMNGGTCADDH----CQCQKGYIGTYCGQPVCE---NGCQN 186
Query: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVD 1335
GG C + +C C F G +CE D
Sbjct: 187 GGRC---IGPNRCACVYGFTGPQCERD 210
Score = 51.2 bits (121), Expect = 7e-06
Identities = 61/232 (26%), Positives = 83/232 (35%), Gaps = 55/232 (23%)
Query: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWS---GKHCELNIDEC--FSNPCIHGNC 1191
C L +PC CE +CP G + G CE +++EC F C +G C
Sbjct: 921 CATLGAAWGSPC---ERCE-----LDTACPRGLARIKGVTCE-DVNECEVFPGVCPNGRC 971
Query: 1192 SDRVAAYHCTCEPGY----TGVNCEVDIDNCQSHQCANGATCISHTNG-----YSCLCFG 1242
+ ++HC C G TG C +DI Q + + CI G C G
Sbjct: 972 VNSKGSFHCECPEGLTLDGTGRVC-LDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030
Query: 1243 NFTGKFCRQSRLP-----STVC---------GNEKTNLTCYNG-------------GNCT 1275
G C + P T+C G+ T Y G C
Sbjct: 1031 AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCR 1090
Query: 1276 EFQTELKCMCRPGFTGEWCEK---DIDECASDPCVNG-GLCQDLLNKFQCLC 1323
KC C GF + E+ DIDEC P + G G+C + F+C C
Sbjct: 1091 NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECEC 1142
Score = 44.7 bits (104), Expect = 6e-04
Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 9/71 (12%)
Query: 885 CAGDNSCKSNP--CHNGGVCHSRWDDFSCSCPALTS----GKACEEVQWC-GFSPCPHGA 937
C +N C S P C G+C + FSC C S G CE+V C G C HG
Sbjct: 2569 CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG- 2627
Query: 938 QCQPVLQGFEC 948
CQ +L G+ C
Sbjct: 2628 -CQNILGGYRC 2637
Score = 39.7 bits (91), Expect = 0.021
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 883 QGCAGDNSCKSNP--CHNGGVCHSRWDDFSCSCPA----LTSGKACEEVQWCGFSPCPHG 936
+ C + C N C NG +C + +SC+CP T + CE++ C +PC +G
Sbjct: 806 RNCIDIDECLVNRLLCDNG-LCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNG 864
Query: 937 AQCQPVLQGFEC 948
A C+ L F C
Sbjct: 865 A-CRNNLGSFNC 875
Score = 37.4 bits (85), Expect = 0.10
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 3/51 (5%)
Query: 669 GCVRKDWCESQP--CQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFG 717
GCV ++ C ++P C++ GRC+N+ SY+C+C+ ++ + E + R G
Sbjct: 2335 GCVDENECRTKPGICEN-GRCVNIIGSYRCECNEGFQSSSSGTECLDNRQG 2384
Score = 35.8 bits (81), Expect = 0.30
Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 10/98 (10%)
Query: 613 LGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDWNHITLENISS-------GSSLN 665
+GG VG G + + T C + N + +SS G +
Sbjct: 471 VGGAGVGAGGQGPIITGLTILNQTIDI--CKHHANLCLNGRCIPTVSSYRCECNMGYKQD 528
Query: 666 VKAGCVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYE 703
C+ D C S PC + G C+N SY C CH ++
Sbjct: 529 ANGDCIDVDECTSNPC-TNGDCVNTPGSYYCKCHAGFQ 565
Score = 35.4 bits (80), Expect = 0.39
Identities = 14/32 (43%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 882 TQGCAGDNSCKSNPCHNGGVCHSRWDDFSCSC 913
T+ C N C+SNPC N G C + F+C C
Sbjct: 847 TETCEDINECESNPCVN-GACRNNLGSFNCEC 877
Score = 34.7 bits (78), Expect = 0.66
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPA----LTSGKACEEVQWC--GFSPCPHGAQ 938
C + C SNPC NG C + + C C A + +AC ++ C C +G +
Sbjct: 533 CIDVDECTSNPCTNGD-CVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNG-R 590
Query: 939 CQPVLQGFECIANAVF 954
C F+CI NA F
Sbjct: 591 CVNTDGSFQCICNAGF 606
Score = 34.7 bits (78), Expect = 0.66
Identities = 17/68 (25%), Positives = 26/68 (38%), Gaps = 4/68 (5%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTS----GKACEEVQWCGFSPCPHGAQCQ 940
C +N C + C++ + C+CP+ S AC +V C S P C
Sbjct: 2652 CVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCS 2711
Query: 941 PVLQGFEC 948
G+ C
Sbjct: 2712 NTEGGYLC 2719
Score = 33.1 bits (74), Expect = 1.9
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 659 SSGSSLNVKAGCVRKDWCESQP--CQSRGRCINLWLSYQCDCHRPYE 703
++G L+ CV ++ C P C S G C++L SYQC CH ++
Sbjct: 1879 AAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGFK 1924
Score = 32.7 bits (73), Expect = 2.5
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 7/72 (9%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCP---ALTSG-KACEEVQWC--GFSPC-PHGA 937
C N C NP C + + + C+CP AL K C+++ C G C G
Sbjct: 2251 CEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGM 2310
Query: 938 QCQPVLQGFECI 949
C+ ++ F CI
Sbjct: 2311 MCKNLIGTFMCI 2322
Score = 32.3 bits (72), Expect = 3.3
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
Query: 883 QGCAGDNSCKSNPCH-NGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSP--CPH 935
+ C + C+ NP GG C + F C CP S + C ++ C S C +
Sbjct: 1154 KNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRN 1213
Query: 936 GAQCQPVLQGFECIAN 951
G +C ++ ++C N
Sbjct: 1214 G-KCVNMIGTYQCSCN 1228
Score = 32.0 bits (71), Expect = 4.3
Identities = 30/110 (27%), Positives = 40/110 (36%), Gaps = 36/110 (32%)
Query: 1135 TGCLQLNVCNS--NPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS 1192
+ C +N C+S NPC +G C + Y C CP G+
Sbjct: 2691 SACHDVNECSSSKNPCNYG--CSNTEGGYLCGCPPGYY---------------------- 2726
Query: 1193 DRVAAYHCTCEPG-----YTGVNCEVDIDNCQSHQCANGATCISHTNGYS 1237
RV HC G Y ++ EVD +N S + A NGYS
Sbjct: 2727 -RVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPE----ACYECKINGYS 2771
Score = 31.6 bits (70), Expect = 5.6
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 10/76 (13%)
Query: 882 TQGCAGDNSCKSNP--CHNGGVCHSRWDDFSCSCPA----LTSGKACEEVQWCGFSP--C 933
T C + C++ P C GG C + F C CPA + + CE++ C P C
Sbjct: 271 TGACQDVDECQAIPGICQ-GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGIC 329
Query: 934 PHGAQCQPVLQGFECI 949
G +C + + C+
Sbjct: 330 ETG-ECSNTVGSYFCV 344
Score = 31.6 bits (70), Expect = 5.6
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 662 SSLNVKAGCVRKDWCESQPCQSRG-RCINLWLSYQCDCHRPYE 703
S + C+ D CE P RG C+N S+QCDC +E
Sbjct: 1148 SGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHE 1190
Score = 31.6 bits (70), Expect = 5.6
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 6/44 (13%)
Query: 670 CVRKDWCESQP--CQSRGRCINLWLSYQCDCHRPYE----GPNC 707
C+ + C SQP C ++G C N S+ C+C R + G NC
Sbjct: 2569 CIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC 2612
Score = 31.2 bits (69), Expect = 7.3
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 4/39 (10%)
Query: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAG 714
CE+ CQ+ GRCI +C C + GP C R+Y G
Sbjct: 180 CENG-CQNGGRCIG---PNRCACVYGFTGPQCERDYRTG 214
Score = 31.2 bits (69), Expect = 7.3
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 8/70 (11%)
Query: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCP----ALTSGKACEEVQWCGFSPCPHGAQ-- 938
C + C +P +C + + CSCP GK C+++ C H Q
Sbjct: 2489 CIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDEC--QTKQHNCQFL 2546
Query: 939 CQPVLQGFEC 948
C L GF C
Sbjct: 2547 CVNTLGGFTC 2556
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,013,984
Number of Sequences: 37866
Number of extensions: 3243504
Number of successful extensions: 26463
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 264
Number of HSP's that attempted gapping in prelim test: 6682
Number of HSP's gapped (non-prelim): 7512
length of query: 1406
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1291
effective length of database: 13,892,928
effective search space: 17935770048
effective search space used: 17935770048
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.