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Search of human proteins with 40804470
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
isoform 2 [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i... 1032 0.0
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i... 902 0.0
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i... 836 0.0
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ... 712 0.0
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ... 711 0.0
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i... 669 0.0
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ... 667 0.0
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ... 666 0.0
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i... 665 0.0
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ... 665 0.0
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ... 660 0.0
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i... 596 e-170
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i... 594 e-170
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i... 574 e-164
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ... 507 e-143
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [... 475 e-134
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 46 7e-05
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 46 7e-05
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 40 0.004
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 40 0.005
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 40 0.005
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 40 0.005
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 39 0.015
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens] 38 0.026
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 38 0.026
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 37 0.044
gi|60097902 filaggrin [Homo sapiens] 36 0.098
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 36 0.098
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 36 0.098
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 34 0.37
>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
isoform 2 [Homo sapiens]
Length = 523
Score = 1032 bits (2668), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA
Sbjct: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
Query: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP
Sbjct: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
Query: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR
Sbjct: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
Query: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAK 240
LGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAK
Sbjct: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAK 240
Query: 241 TSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 300
TSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF
Sbjct: 241 TSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 300
Query: 301 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 360
LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART
Sbjct: 301 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 360
Query: 361 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 420
LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE
Sbjct: 361 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 420
Query: 421 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 480
KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA
Sbjct: 421 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 480
Query: 481 SPAPVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVPQEQEHAM 523
SPAPVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVPQEQEHAM
Sbjct: 481 SPAPVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVPQEQEHAM 523
>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
isoform 3 [Homo sapiens]
Length = 478
Score = 902 bits (2331), Expect = 0.0
Identities = 471/523 (90%), Positives = 472/523 (90%), Gaps = 45/523 (8%)
Query: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA
Sbjct: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
Query: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP
Sbjct: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
Query: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR
Sbjct: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
Query: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAK 240
LGSSKSGDNSSSSLGDVVTGTRRP
Sbjct: 181 LGSSKSGDNSSSSLGDVVTGTRRP------------------------------------ 204
Query: 241 TSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 300
TPP K+ K TEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF
Sbjct: 205 -------TPPASAKQKQ--KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 255
Query: 301 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 360
LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART
Sbjct: 256 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 315
Query: 361 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 420
LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE
Sbjct: 316 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 375
Query: 421 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 480
KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA
Sbjct: 376 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 435
Query: 481 SPAPVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVPQEQEHAM 523
SPAPVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVPQEQEHAM
Sbjct: 436 SPAPVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVPQEQEHAM 478
>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
isoform 1 [Homo sapiens]
Length = 598
Score = 836 bits (2160), Expect = 0.0
Identities = 439/495 (88%), Positives = 440/495 (88%), Gaps = 45/495 (9%)
Query: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA
Sbjct: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
Query: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP
Sbjct: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
Query: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR
Sbjct: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
Query: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAK 240
LGSSKSGDNSSSSLGDVVTGTRRP
Sbjct: 181 LGSSKSGDNSSSSLGDVVTGTRRP------------------------------------ 204
Query: 241 TSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 300
TPP K+ K TEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF
Sbjct: 205 -------TPPASAKQKQ--KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 255
Query: 301 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 360
LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART
Sbjct: 256 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 315
Query: 361 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 420
LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE
Sbjct: 316 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 375
Query: 421 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 480
KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA
Sbjct: 376 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 435
Query: 481 SPAPVSNLQVQVLTS 495
SPAPVSNLQ L S
Sbjct: 436 SPAPVSNLQGPYLAS 450
>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
isoform 2 [Homo sapiens]
Length = 660
Score = 712 bits (1838), Expect = 0.0
Identities = 368/504 (73%), Positives = 421/504 (83%), Gaps = 23/504 (4%)
Query: 1 MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45
MVQ+ MS+ P + QEI ME+ + GK ++RK RFK SDGST
Sbjct: 1 MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
Query: 46 SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105
SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 60 SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
Query: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165
RTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
Query: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLEL 225
+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+S A ++D L
Sbjct: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS-------AIDIDATGL 232
Query: 226 EEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLK 285
+ EE ++ S K S +SVT+P KR+PFFKKTEH PPYDVVPSMRP++LVGPSLK
Sbjct: 233 DAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLK 292
Query: 286 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 345
GYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLA
Sbjct: 293 GYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLA 352
Query: 346 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 405
EVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRG
Sbjct: 353 EVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRG 412
Query: 406 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 465
KSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ P
Sbjct: 413 KSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLP 472
Query: 466 NPLLNRTMATAALAASPAPVSNLQ 489
NPLL+RT+AT++L SP SN Q
Sbjct: 473 NPLLSRTLATSSLPLSPTLASNSQ 496
>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
isoform 6 [Homo sapiens]
Length = 632
Score = 711 bits (1834), Expect = 0.0
Identities = 357/461 (77%), Positives = 405/461 (87%), Gaps = 7/461 (1%)
Query: 29 GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88
GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 15 GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
Query: 89 ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148
A AQLEKAKTKPVAFAVRTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 75 AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
Query: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208
LVKEGCE+GFIPSPVKL+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+
Sbjct: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
Query: 209 SGNEMTNLAFELDPLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPY 268
S A ++D L+ EE ++ S K S +SVT+P KR+PFFKKTEH PPY
Sbjct: 195 S-------AIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPY 247
Query: 269 DVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNN 328
DVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNN
Sbjct: 248 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNN 307
Query: 329 PSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVY 388
PSKH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY
Sbjct: 308 PSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVY 367
Query: 389 IKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAE 448
+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+
Sbjct: 368 VKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLAD 427
Query: 449 YLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ 489
YLEAYWKATHPPSS+ PNPLL+RT+AT++L SP SN Q
Sbjct: 428 YLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQ 468
>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
isoform 4 [Homo sapiens]
Length = 636
Score = 669 bits (1725), Expect = 0.0
Identities = 354/505 (70%), Positives = 405/505 (80%), Gaps = 49/505 (9%)
Query: 1 MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45
MVQ+ MS+ P + QEI ME+ + GK ++RK RFK SDGST
Sbjct: 1 MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
Query: 46 SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105
SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 60 SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
Query: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165
RTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
Query: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLEL 225
+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+SG
Sbjct: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSG--------------- 224
Query: 226 EEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFK-KTEHVPPYDVVPSMRPIILVGPSL 284
A+ ++ KT+ F++ TEH PPYDVVPSMRP++LVGPSL
Sbjct: 225 ----AKSADEQDQWKTAGL-------------FWRFTTEHTPPYDVVPSMRPVVLVGPSL 267
Query: 285 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSL 344
KGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSL
Sbjct: 268 KGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSL 327
Query: 345 AEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSR 404
AEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSR
Sbjct: 328 AEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSR 387
Query: 405 GKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTP 464
GKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+
Sbjct: 388 GKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSL 447
Query: 465 PNPLLNRTMATAALAASPAPVSNLQ 489
PNPLL+RT+AT++L SP SN Q
Sbjct: 448 PNPLLSRTLATSSLPLSPTLASNSQ 472
>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
isoform 8 [Homo sapiens]
Length = 608
Score = 667 bits (1721), Expect = 0.0
Identities = 343/462 (74%), Positives = 389/462 (84%), Gaps = 33/462 (7%)
Query: 29 GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88
GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 15 GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
Query: 89 ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148
A AQLEKAKTKPVAFAVRTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 75 AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
Query: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208
LVKEGCE+GFIPSPVKL+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+
Sbjct: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
Query: 209 SGNEMTNLAFELDPLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFK-KTEHVPP 267
SG A+ ++ KT+ F++ TEH PP
Sbjct: 195 SG-------------------AKSADEQDQWKTAGL-------------FWRFTTEHTPP 222
Query: 268 YDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLN 327
YDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLN
Sbjct: 223 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLN 282
Query: 328 NPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIV 387
NPSKH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIV
Sbjct: 283 NPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIV 342
Query: 388 YIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLA 447
Y+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA
Sbjct: 343 YVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLA 402
Query: 448 EYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ 489
+YLEAYWKATHPPSS+ PNPLL+RT+AT++L SP SN Q
Sbjct: 403 DYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQ 444
>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
isoform 1 [Homo sapiens]
Length = 605
Score = 666 bits (1718), Expect = 0.0
Identities = 334/435 (76%), Positives = 380/435 (87%), Gaps = 7/435 (1%)
Query: 55 VRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPS 114
V GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ +
Sbjct: 14 VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
Query: 115 PGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQ 174
D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL EQ
Sbjct: 74 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
Query: 175 KLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGE 234
+ +Q + SSKSG NSSSSLGD+V +R+ TPP+S A ++D L+ EE ++
Sbjct: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS-------AIDIDATGLDAEENDIPA 186
Query: 235 QSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQ 294
S K S +SVT+P KR+PFFKKTEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQ
Sbjct: 187 NHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQ 246
Query: 295 KALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERI 354
KALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERI
Sbjct: 247 KALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERI 306
Query: 355 FELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNV 414
FELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNV
Sbjct: 307 FELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNV 366
Query: 415 QIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMA 474
Q+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+A
Sbjct: 367 QMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLA 426
Query: 475 TAALAASPAPVSNLQ 489
T++L SP SN Q
Sbjct: 427 TSSLPLSPTLASNSQ 441
>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
isoform 7 [Homo sapiens]
Length = 612
Score = 665 bits (1716), Expect = 0.0
Identities = 333/432 (77%), Positives = 379/432 (87%), Gaps = 7/432 (1%)
Query: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ + D
Sbjct: 24 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 83
Query: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL EQ+ +
Sbjct: 84 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 143
Query: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSG 237
Q + SSKSG NSSSSLGD+V +R+ TPP+S A ++D L+ EE ++
Sbjct: 144 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS-------AIDIDATGLDAEENDIPANHR 196
Query: 238 SAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKAL 297
S K S +SVT+P KR+PFFKKTEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKAL
Sbjct: 197 SPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 256
Query: 298 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFEL 357
FDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFEL
Sbjct: 257 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 316
Query: 358 ARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIA 417
ARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+
Sbjct: 317 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 376
Query: 418 ASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAA 477
A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++
Sbjct: 377 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 436
Query: 478 LAASPAPVSNLQ 489
L SP SN Q
Sbjct: 437 LPLSPTLASNSQ 448
>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
isoform 3 [Homo sapiens]
Length = 606
Score = 665 bits (1716), Expect = 0.0
Identities = 333/432 (77%), Positives = 379/432 (87%), Gaps = 7/432 (1%)
Query: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ + D
Sbjct: 18 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 77
Query: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL EQ+ +
Sbjct: 78 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 137
Query: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSG 237
Q + SSKSG NSSSSLGD+V +R+ TPP+S A ++D L+ EE ++
Sbjct: 138 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS-------AIDIDATGLDAEENDIPANHR 190
Query: 238 SAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKAL 297
S K S +SVT+P KR+PFFKKTEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKAL
Sbjct: 191 SPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 250
Query: 298 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFEL 357
FDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFEL
Sbjct: 251 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 310
Query: 358 ARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIA 417
ARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+
Sbjct: 311 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 370
Query: 418 ASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAA 477
A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++
Sbjct: 371 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 430
Query: 478 LAASPAPVSNLQ 489
L SP SN Q
Sbjct: 431 LPLSPTLASNSQ 442
>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
isoform 5 [Homo sapiens]
Length = 622
Score = 660 bits (1703), Expect = 0.0
Identities = 350/504 (69%), Positives = 396/504 (78%), Gaps = 61/504 (12%)
Query: 1 MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45
MVQ+ MS+ P + QEI ME+ + GK ++RK RFK SDGST
Sbjct: 1 MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
Query: 46 SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105
SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 60 SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
Query: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165
RTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
Query: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLEL 225
+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+
Sbjct: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRK---------------------- 217
Query: 226 EEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLK 285
+TPP K+ K TEH PPYDVVPSMRP++LVGPSLK
Sbjct: 218 ---------------------STPPSSAKQKQ--KSTEHTPPYDVVPSMRPVVLVGPSLK 254
Query: 286 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 345
GYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLA
Sbjct: 255 GYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLA 314
Query: 346 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 405
EVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRG
Sbjct: 315 EVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRG 374
Query: 406 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 465
KSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ P
Sbjct: 375 KSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLP 434
Query: 466 NPLLNRTMATAALAASPAPVSNLQ 489
NPLL+RT+AT++L SP SN Q
Sbjct: 435 NPLLSRTLATSSLPLSPTLASNSQ 458
>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
Length = 520
Score = 596 bits (1537), Expect = e-170
Identities = 315/489 (64%), Positives = 366/489 (74%), Gaps = 61/489 (12%)
Query: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
Query: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
Query: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
Query: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAKTS 242
KS NSSSSLG++V+GT R TP ++ +
Sbjct: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ---------------------------- 204
Query: 243 VSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLK 302
K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLK
Sbjct: 205 -----------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLK 247
Query: 303 HRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 362
HRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEVQSEIERIFELAR+LQ
Sbjct: 248 HRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQ 307
Query: 363 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKL 422
LV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+ A++KL
Sbjct: 308 LVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKL 367
Query: 423 AQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASP 482
AQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP PLL R + + AL+ P
Sbjct: 368 AQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYP 427
Query: 483 APVSNLQVQ 491
+S LQ Q
Sbjct: 428 TAISGLQSQ 436
>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
isoform c [Homo sapiens]
Length = 502
Score = 594 bits (1531), Expect = e-170
Identities = 311/459 (67%), Positives = 356/459 (77%), Gaps = 52/459 (11%)
Query: 34 RKGRFKRSDGSTSSDTTSNSFV-RQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQ 92
R+ R KRSDGST TS SF+ RQGSA+SYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 11 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 66
Query: 93 LEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKE 152
LE+AK+KPVAFAV+TNV Y + ++VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKE
Sbjct: 67 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 126
Query: 153 GCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNE 212
GCE+GFIPSP++L+++R+ QEQK + R KS NSSSSLG++V+GT R TP ++ +
Sbjct: 127 GCEIGFIPSPLRLENIRIQQEQK--RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 184
Query: 213 MTNLAFELDPLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVP 272
K TEH+PPYDVVP
Sbjct: 185 KQ---------------------------------------------KVTEHIPPYDVVP 199
Query: 273 SMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKH 332
SMRP++LVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK
Sbjct: 200 SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKR 259
Query: 333 IIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKIT 392
IIERSNTRSSLAEVQSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++
Sbjct: 260 AIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVS 319
Query: 393 SPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEA 452
SPKVLQRLIKSRGKSQSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEA
Sbjct: 320 SPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEA 379
Query: 453 YWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQ 491
YW+ATH SSTP PLL R + + AL+ P +S LQ Q
Sbjct: 380 YWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQ 418
>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
isoform a [Homo sapiens]
Length = 486
Score = 574 bits (1479), Expect = e-164
Identities = 296/434 (68%), Positives = 339/434 (78%), Gaps = 47/434 (10%)
Query: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
GSA+SYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + +
Sbjct: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
Query: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
+VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK
Sbjct: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK-- 133
Query: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSG 237
+ R KS NSSSSLG++V+GT R TP ++ +
Sbjct: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ----------------------- 170
Query: 238 SAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKAL 297
K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKAL
Sbjct: 171 ----------------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 208
Query: 298 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFEL 357
FDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEVQSEIERIFEL
Sbjct: 209 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFEL 268
Query: 358 ARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIA 417
AR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+
Sbjct: 269 ARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLV 328
Query: 418 ASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAA 477
A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP PLL R + + A
Sbjct: 329 AADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTA 388
Query: 478 LAASPAPVSNLQVQ 491
L+ P +S LQ Q
Sbjct: 389 LSPYPTAISGLQSQ 402
>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
isoform d [Homo sapiens]
Length = 458
Score = 507 bits (1305), Expect = e-143
Identities = 272/425 (64%), Positives = 317/425 (74%), Gaps = 61/425 (14%)
Query: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
Query: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
Query: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
Query: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAKTS 242
KS NSSSSLG++V+GT R TP ++ +
Sbjct: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ---------------------------- 204
Query: 243 VSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLK 302
K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLK
Sbjct: 205 -----------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLK 247
Query: 303 HRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 362
HRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEVQSEIERIFELAR+LQ
Sbjct: 248 HRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQ 307
Query: 363 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKL 422
LV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+ A++KL
Sbjct: 308 LVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKL 367
Query: 423 AQCPP 427
AQCPP
Sbjct: 368 AQCPP 372
>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
[Homo sapiens]
Length = 484
Score = 475 bits (1223), Expect = e-134
Identities = 266/465 (57%), Positives = 314/465 (67%), Gaps = 78/465 (16%)
Query: 58 GSAESYTSRPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG 116
GSA+SYTSRPS DSDVSLEEDRE+ R+E E QA QLE+AK KPVAFAVRTNV Y
Sbjct: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
Query: 117 DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKL 176
+E PVQG + FE KDFLHIKEKY+NDWWIGRLVKEG ++ FI
Sbjct: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFI----------------- 118
Query: 177 RQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQS 236
P+P L+ + L++E+ +
Sbjct: 119 ---------------------------PSPQ-----------RLESIRLKQEQKARRSGN 140
Query: 237 GSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKA 296
S+ + + + +PPP + K+ EHVPPYDVVPSMRP++LVGPSLKGYEVTDMMQKA
Sbjct: 141 PSSLSDIGNRRSPPPSLAKQKQ-KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKA 199
Query: 297 LFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFE 356
LFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFE
Sbjct: 200 LFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFE 259
Query: 357 LARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQI 416
LA++LQLV LDADTINHPAQL+KTSLAPIIV++K++SPKVLQRLI+SRGKSQ KHL VQ+
Sbjct: 260 LAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQM 319
Query: 417 AASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATA 476
A +KL QCPPE FD+ILDENQLEDACEHLAEYLE YW+ATH P+ P
Sbjct: 320 MAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPGP------------ 367
Query: 477 ALAASPAPVSNLQVQVLTSLRRNLGFWGGLESS--QRGSVVPQEQ 519
L P+ + LQ Q L R G E S +R S++P ++
Sbjct: 368 GLLGPPSAIPGLQNQQLLGER-------GEEHSPLERDSLMPSDE 405
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 46.2 bits (108), Expect = 7e-05
Identities = 76/365 (20%), Positives = 142/365 (38%), Gaps = 57/365 (15%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG + F+ D LH+ +++WW R V E EVG IPS
Sbjct: 586 VRALFDYDKTKDSGLPSQG--LNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPS 643
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELD 221
+++ + + ++ N SK+ D S + NL
Sbjct: 644 KRRVEKKERARLKTVKFN----SKTRDKGQS---------------FNDKRKKNLFSRKF 684
Query: 222 PLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSM-----RP 276
P ++++E +++ A V+S + R + E+V Y+ V RP
Sbjct: 685 PFYKNKDQSE--QETSDADQHVTSNASDSESSYR----GQEEYVLSYEPVNQQEVNYTRP 738
Query: 277 IILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL---------AKRSVL 326
+I++GP + D + L +F + TR D + ++ +
Sbjct: 739 VIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQME 792
Query: 327 NNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPII 386
+ +H IE + L + ++ + E+A + LD N +L L PI
Sbjct: 793 KDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVSG-NAIKRLQIAQLYPIS 849
Query: 387 VYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHL 446
++IK PK ++ +++ + + + KL Q E F I+ + LED +
Sbjct: 850 IFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQV 906
Query: 447 AEYLE 451
+ +E
Sbjct: 907 KQIIE 911
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 46.2 bits (108), Expect = 7e-05
Identities = 71/364 (19%), Positives = 141/364 (38%), Gaps = 52/364 (14%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG++ ++ D LH+ +++WW RLV E ++G IPS
Sbjct: 169 VRALFDYDRTRDSCLPSQGLSFSYG--DILHVINASDDEWWQARLVTPHGESEQIGVIPS 226
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELD 221
+++ + + ++ + + S + R P E N+A
Sbjct: 227 KKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKE--NMA---- 280
Query: 222 PLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVG 281
+E+ + EQ ++ TS S ++ + + T Y RP+I++G
Sbjct: 281 ------QESSIQEQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHY-----ARPVIILG 329
Query: 282 PSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISLAKRSVLNNPSKHIIIERSNT 340
P + D + L H+F + TR D + ++ H ++ R
Sbjct: 330 P------MKDRVNDDLISEFPHKFGSCVPHTTRPRRD------NEVDGQDYHFVVSREQM 377
Query: 341 RSSLAEVQ-------------SEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIV 387
+ + + + I+ + +A + LD N +L + L PI +
Sbjct: 378 EKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAI 436
Query: 388 YIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLA 447
+IK PK ++ L++ + + N + KL Q E F I+ + LE+ +
Sbjct: 437 FIK---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIK 493
Query: 448 EYLE 451
+ +E
Sbjct: 494 QIIE 497
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 40.4 bits (93), Expect = 0.004
Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 14/133 (10%)
Query: 100 PVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFI 159
P V+ + YNP + +P + + F + L I + + +WW VKEG G I
Sbjct: 215 PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLI 274
Query: 160 PSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFE 219
PS + L+E++ R + DNS G + + ++ + N F+
Sbjct: 275 PS-------QFLEEKRKAFVR----RDWDNSGPFCGTISSKKKKKMMYLT---TRNAEFD 320
Query: 220 LDPLELEEEEAEL 232
+++ EE A++
Sbjct: 321 RHEIQIYEEVAKM 333
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLV-KEGCEVGFIPSP 162
VR Y+P+ D +P + I F D + I K +++WW G+L + G IPSP
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 646
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLV-KEGCEVGFIPSP 162
VR Y+P+ D +P + I F D + I K +++WW G+L + G IPSP
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 652
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLV-KEGCEVGFIPSP 162
VR Y+P+ D +P + I F D + I K +++WW G+L + G IPSP
Sbjct: 617 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 675
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 38.5 bits (88), Expect = 0.015
Identities = 72/363 (19%), Positives = 129/363 (35%), Gaps = 75/363 (20%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG + F+ D LH+ +++WW R V E EVG IPS
Sbjct: 586 VRALFDYDKTKDSGLPSQG--LNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPS 643
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKS---GDNSSSSLGDVVTGTRRPTPPASGNEMTNLAF 218
+++ + + ++ N K D S L V + G E L++
Sbjct: 644 KRRVEKKERARLKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSY 703
Query: 219 ELDPLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPII 278
E P+ +E V RP+I
Sbjct: 704 E--PVNQQE-------------------------------------------VNYTRPVI 718
Query: 279 LVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL---------AKRSVLNN 328
++GP + D + L +F + TR D + ++ + +
Sbjct: 719 ILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKD 772
Query: 329 PSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVY 388
+H IE + L + ++ + E+A + LD N +L L PI ++
Sbjct: 773 IQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVSG-NAIKRLQIAQLYPISIF 829
Query: 389 IKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAE 448
IK PK ++ +++ + + + KL Q E F I+ + LED + +
Sbjct: 830 IK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQ 886
Query: 449 YLE 451
+E
Sbjct: 887 IIE 889
>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
Length = 466
Score = 37.7 bits (86), Expect = 0.026
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 94 EKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEG 153
++++ + +R Y+P + +P + + F D + I K +++WW GR+
Sbjct: 152 QQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINKDDSNWWQGRVEGSS 211
Query: 154 CE-VGFIPSP 162
E G IPSP
Sbjct: 212 KESAGLIPSP 221
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 37.7 bits (86), Expect = 0.026
Identities = 71/370 (19%), Positives = 139/370 (37%), Gaps = 66/370 (17%)
Query: 92 QLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK 151
Q++ K V+ + Y+PS VP + + ++F+ D LH+ + + +WW + +
Sbjct: 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYR 394
Query: 152 EGCE-----VGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTP 206
EG E G +P Q+++ + + K + S +R
Sbjct: 395 EGDEDNQPLAGLVPGK------SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV 448
Query: 207 PASGNEMTNLAFELDPLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVP 266
+ N+ N ++ + + L EE L Q + K
Sbjct: 449 LYNANK--NDDYDNEEI-LTYEEMSLYHQPANRK-------------------------- 479
Query: 267 PYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISLA---- 321
RPIIL+GP G + +++ L + K RF + TR D +A
Sbjct: 480 --------RPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
Query: 322 ----KRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQL 377
+++ + + IE +L + R + + L++L ++ L
Sbjct: 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK---TL 585
Query: 378 SKTSLAPIIVYIKITSPKVLQRLIKSRGKS-QSKHLNVQIAASEKLAQCPPEMFDIILDE 436
+ L P I++I S + L+ L+ GK+ + + L I + ++ Q FD +
Sbjct: 586 RNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
Query: 437 NQLEDACEHL 446
+ L+ A + L
Sbjct: 646 SDLDKAYQEL 655
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 37.0 bits (84), Expect = 0.044
Identities = 66/364 (18%), Positives = 131/364 (35%), Gaps = 84/364 (23%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG++ ++ D LH+ +++WW RLV E ++G IPS
Sbjct: 506 VRALFDYDRTRDSCLPSQGLSFSYG--DILHVINASDDEWWQARLVTPHGESEQIGVIPS 563
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELD 221
+++ + + ++ + + L D G + G E L++E
Sbjct: 564 KKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKN----LKGQEDAILSYE-- 617
Query: 222 PLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVG 281
P+ +E + RP+I++G
Sbjct: 618 PVTRQE-------------------------------------------IHYARPVIILG 634
Query: 282 PSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISLAKRSVLNNPSKHIIIERSNT 340
P + D + L H+F + TR D + ++ H ++ R
Sbjct: 635 P------MKDRVNDDLISEFPHKFGSCVPHTTRPRRD------NEVDGQDYHFVVSREQM 682
Query: 341 RSSLAEVQ-------------SEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIV 387
+ + + + I+ + +A + LD N +L + L PI +
Sbjct: 683 EKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAI 741
Query: 388 YIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLA 447
+IK PK ++ L++ + + N + KL Q E F I+ + LE+ +
Sbjct: 742 FIK---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIK 798
Query: 448 EYLE 451
+ +E
Sbjct: 799 QIIE 802
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 35.8 bits (81), Expect = 0.098
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQG-SAES 62
++ SRG S+ + +D G S+ G + S+ +D++ +S V QG S+
Sbjct: 2176 RSDASRGQ-SGSRSASRKTYDKEQSGDGSRHSGSHHH-EASSWADSSRHSLVGQGQSSGP 2233
Query: 63 YTSRPSDSDVSLEEDREALRKEAERQA 89
TSRP S VS + D E +++ER++
Sbjct: 2234 RTSRPRGSSVSQDSDSEGHSEDSERRS 2260
Score = 30.8 bits (68), Expect = 3.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 3 QKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQG-SAE 61
+++ +SRG S+ + + + G S+ G + + S+ +D++ +S V QG S+
Sbjct: 1850 ERSDVSRGQ-SGSRSVSRQTRNEKQSGDGSRHSGS-RHHEASSRADSSRHSQVGQGQSSG 1907
Query: 62 SYTSRPSDSDVSLEEDREALRKEAER 87
TSR S VS + D + +++ER
Sbjct: 1908 PRTSRNQGSSVSQDSDSQGHSEDSER 1933
Score = 30.4 bits (67), Expect = 4.1
Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 28 QGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAE-SYTSRPSDSDVSLEEDREALRKEAE 86
Q + R + + S+ +D + +S QG +E S TSR S VS + D E +++E
Sbjct: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960
Query: 87 R 87
R
Sbjct: 961 R 961
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 29 GKYSKRKGRFKRSDGSTSSDTTSNSFVRQG-SAESYTSRPSDSDVSLEEDREALRKEAER 87
G S+ G + + ST + ++ +S V QG SA S TSR S VS + D E +++ER
Sbjct: 1551 GDGSRHSGS-RHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSER 1609
Query: 88 QA 89
++
Sbjct: 1610 RS 1611
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 35.8 bits (81), Expect = 0.098
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ S +P QG ++F+ D LH+ +++WW R V + E+G IPS
Sbjct: 438 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 495
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTR 202
+++ + + ++ N LGD GT+
Sbjct: 496 KRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTK 536
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 35.8 bits (81), Expect = 0.098
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ S +P QG ++F+ D LH+ +++WW R V + E+G IPS
Sbjct: 23 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 80
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTR 202
+++ + + ++ N LGD GT+
Sbjct: 81 KRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTK 121
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 33.9 bits (76), Expect = 0.37
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ S +P QG ++F+ D LH+ +++WW R V + E+G IPS
Sbjct: 646 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 703
Query: 162 PVKLD 166
+++
Sbjct: 704 KRRVE 708
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,901,185
Number of Sequences: 37866
Number of extensions: 978280
Number of successful extensions: 3930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 3817
Number of HSP's gapped (non-prelim): 174
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.