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Search of human proteins with 40804468
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
isoform 1 [Homo sapiens]
(598 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i... 1202 0.0
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i... 876 0.0
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i... 843 0.0
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ... 755 0.0
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i... 732 0.0
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ... 731 0.0
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ... 728 0.0
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ... 726 0.0
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ... 681 0.0
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i... 681 0.0
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ... 681 0.0
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i... 629 e-180
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i... 626 e-179
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i... 606 e-173
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ... 538 e-153
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [... 532 e-151
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 51 3e-06
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 49 2e-05
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 47 5e-05
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 47 7e-05
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 47 7e-05
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 44 3e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 43 7e-04
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 43 7e-04
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 41 0.004
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 41 0.004
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 40 0.006
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 40 0.006
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 40 0.006
gi|46852172 kinesin family member 13B [Homo sapiens] 40 0.006
>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
isoform 1 [Homo sapiens]
Length = 598
Score = 1202 bits (3110), Expect = 0.0
Identities = 598/598 (100%), Positives = 598/598 (100%)
Query: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA
Sbjct: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
Query: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP
Sbjct: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
Query: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR
Sbjct: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
Query: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLK 240
LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLK
Sbjct: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLK 240
Query: 241 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 300
GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA
Sbjct: 241 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 300
Query: 301 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 360
EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG
Sbjct: 301 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 360
Query: 361 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 420
KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP
Sbjct: 361 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 420
Query: 421 NPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYP 480
NPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYP
Sbjct: 421 NPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYP 480
Query: 481 SSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGT 540
SSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGT
Sbjct: 481 SSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGT 540
Query: 541 PPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
PPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR
Sbjct: 541 PPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
isoform 3 [Homo sapiens]
Length = 478
Score = 876 bits (2263), Expect = 0.0
Identities = 446/450 (99%), Positives = 446/450 (99%)
Query: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA
Sbjct: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
Query: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP
Sbjct: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
Query: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR
Sbjct: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
Query: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLK 240
LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLK
Sbjct: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLK 240
Query: 241 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 300
GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA
Sbjct: 241 GYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLA 300
Query: 301 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 360
EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG
Sbjct: 301 EVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 360
Query: 361 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 420
KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP
Sbjct: 361 KSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPP 420
Query: 421 NPLLNRTMATAALAASPAPVSNLQGPYLAS 450
NPLLNRTMATAALAASPAPVSNLQ L S
Sbjct: 421 NPLLNRTMATAALAASPAPVSNLQVQVLTS 450
>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
isoform 2 [Homo sapiens]
Length = 523
Score = 843 bits (2179), Expect = 0.0
Identities = 440/495 (88%), Positives = 441/495 (89%), Gaps = 45/495 (9%)
Query: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA
Sbjct: 1 MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSA 60
Query: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP
Sbjct: 61 ESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVP 120
Query: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR
Sbjct: 121 VQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNR 180
Query: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQ-------------------------- 214
LGSSKSGDNSSSSLGDVVTGTRRPTPPAS +
Sbjct: 181 LGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAK 240
Query: 215 -------------------KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 255
K TEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF
Sbjct: 241 TSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDF 300
Query: 256 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 315
LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART
Sbjct: 301 LKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 360
Query: 316 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 375
LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE
Sbjct: 361 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASE 420
Query: 376 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 435
KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA
Sbjct: 421 KLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAA 480
Query: 436 SPAPVSNLQGPYLAS 450
SPAPVSNLQ L S
Sbjct: 481 SPAPVSNLQVQVLTS 495
>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
isoform 5 [Homo sapiens]
Length = 622
Score = 755 bits (1949), Expect = 0.0
Identities = 407/626 (65%), Positives = 473/626 (75%), Gaps = 33/626 (5%)
Query: 1 MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45
MVQ+ MS+ P + QEI ME+ + GK ++RK RFK SDGST
Sbjct: 1 MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
Query: 46 SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105
SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 60 SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
Query: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165
RTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
Query: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDV 225
+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+SAKQKQKSTEH PPYDV
Sbjct: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDV 239
Query: 226 VPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPS 285
VPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPS
Sbjct: 240 VPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPS 299
Query: 286 KHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIK 345
KH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+K
Sbjct: 300 KHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVK 359
Query: 346 ITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYL 405
I+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YL
Sbjct: 360 ISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYL 419
Query: 406 EAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQ------PLERAT 459
EAYWKATHPPSS+ PNPLL+RT+AT++L SP SN QG + GDQ P+ A+
Sbjct: 420 EAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG---SQGDQRTDRSAPIRSAS 476
Query: 460 GEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTE----L 515
P + Q + H R+GT R LSRQ+TFD++T SR+SAY E
Sbjct: 477 QAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDY 536
Query: 516 GDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEE---ELTDNRNRGRNKARY 572
VD + + G R+ + D E+ E R+R ++K RY
Sbjct: 537 SHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRY 596
Query: 573 CAEGGGPVLGRNKNELEGWGRGVYIR 598
C E G V+ + +NE W R VYIR
Sbjct: 597 C-EKDGEVISKKRNEAGEWNRDVYIR 621
>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
isoform 4 [Homo sapiens]
Length = 636
Score = 732 bits (1890), Expect = 0.0
Identities = 400/640 (62%), Positives = 468/640 (73%), Gaps = 47/640 (7%)
Query: 1 MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45
MVQ+ MS+ P + QEI ME+ + GK ++RK RFK SDGST
Sbjct: 1 MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
Query: 46 SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105
SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 60 SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
Query: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165
RTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
Query: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQK---------- 215
+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+S +
Sbjct: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGL 239
Query: 216 ----STEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 271
+TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTA
Sbjct: 240 FWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTA 299
Query: 272 DISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQ 331
DISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQ
Sbjct: 300 DISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQ 359
Query: 332 LSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDE 391
LSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDE
Sbjct: 360 LSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDE 419
Query: 392 NQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASG 451
NQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L SP SN QG + G
Sbjct: 420 NQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG---SQG 476
Query: 452 DQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTP 505
DQ P+ A+ P + Q + H R+GT R LSRQ+TFD++T
Sbjct: 477 DQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQ 536
Query: 506 GSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEE---E 558
SR+SAY E VD + + G R+ + D E+ E
Sbjct: 537 ESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNE 596
Query: 559 LTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
R+R ++K RYC E G V+ + +NE W R VYIR
Sbjct: 597 CNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 635
>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
isoform 8 [Homo sapiens]
Length = 608
Score = 731 bits (1886), Expect = 0.0
Identities = 389/597 (65%), Positives = 452/597 (75%), Gaps = 31/597 (5%)
Query: 29 GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88
GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 15 GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
Query: 89 ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148
A AQLEKAKTKPVAFAVRTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 75 AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
Query: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208
LVKEGCE+GFIPSPVKL+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+
Sbjct: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
Query: 209 SAKQKQK--------------STEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFD 254
S + +TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFD
Sbjct: 195 SGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFD 254
Query: 255 FLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELAR 314
FLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELAR
Sbjct: 255 FLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELAR 314
Query: 315 TLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAAS 374
TLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A+
Sbjct: 315 TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA 374
Query: 375 EKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALA 434
+KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L
Sbjct: 375 DKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLP 434
Query: 435 ASPAPVSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRA 488
SP SN QG + GDQ P+ A+ P + Q + H R+
Sbjct: 435 LSPTLASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRS 491
Query: 489 GTLRALSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPAR 544
GT R LSRQ+TFD++T SR+SAY E VD + + G R
Sbjct: 492 GTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHR 551
Query: 545 QGSWEDEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
+ + D E+ E R+R ++K RYC E G V+ + +NE W R VYIR
Sbjct: 552 ESRHRSRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 607
>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
isoform 2 [Homo sapiens]
Length = 660
Score = 728 bits (1878), Expect = 0.0
Identities = 404/664 (60%), Positives = 472/664 (71%), Gaps = 71/664 (10%)
Query: 1 MVQKTSMSRGPYPPS----QEIPMEVFD-----------PSPQGKYSKRKGRFKRSDGST 45
MVQ+ MS+ P + QEI ME+ + GK ++RK RFK SDGST
Sbjct: 1 MVQR-DMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGST 59
Query: 46 SSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAV 105
SSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAV
Sbjct: 60 SSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAV 119
Query: 106 RTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKL 165
RTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL
Sbjct: 120 RTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKL 179
Query: 166 DSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASA--------------- 210
+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+SA
Sbjct: 180 ENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDI 239
Query: 211 -------------------KQKQ----KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDM 247
K+K+ K TEH PPYDVVPSMRP++LVGPSLKGYEVTDM
Sbjct: 240 PANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDM 299
Query: 248 MQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIE 307
MQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIE
Sbjct: 300 MQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIE 359
Query: 308 RIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHL 367
RIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHL
Sbjct: 360 RIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHL 419
Query: 368 NVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRT 427
NVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT
Sbjct: 420 NVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRT 479
Query: 428 MATAALAASPAPVSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPS 481
+AT++L SP SN QG + GDQ P+ A+ P + Q +
Sbjct: 480 LATSSLPLSPTLASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSA 536
Query: 482 SHPPGRAGTLRALSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAG 537
H R+GT R LSRQ+TFD++T SR+SAY E VD + + G
Sbjct: 537 PHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHG 596
Query: 538 GGTPPARQGSWEDEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRG 594
R+ + D E+ E R+R ++K RYC E G V+ + +NE W R
Sbjct: 597 SSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRD 655
Query: 595 VYIR 598
VYIR
Sbjct: 656 VYIR 659
>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
isoform 6 [Homo sapiens]
Length = 632
Score = 726 bits (1874), Expect = 0.0
Identities = 393/621 (63%), Positives = 456/621 (73%), Gaps = 55/621 (8%)
Query: 29 GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88
GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 15 GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
Query: 89 ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148
A AQLEKAKTKPVAFAVRTNV Y+ + D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 75 AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
Query: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208
LVKEGCE+GFIPSPVKL+++RL EQ+ +Q + SSKSG NSSSSLGD+V +R+ TPP+
Sbjct: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
Query: 209 SA----------------------------------KQKQ----KSTEHVPPYDVVPSMR 230
SA K+K+ K TEH PPYDVVPSMR
Sbjct: 195 SAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMR 254
Query: 231 PIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIII 290
P++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH II
Sbjct: 255 PVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAII 314
Query: 291 ERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPK 350
ERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPK
Sbjct: 315 ERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPK 374
Query: 351 VLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWK 410
VLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWK
Sbjct: 375 VLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWK 434
Query: 411 ATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQ------PLERATGEHAS 464
ATHPPSS+ PNPLL+RT+AT++L SP SN QG + GDQ P+ A+
Sbjct: 435 ATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG---SQGDQRTDRSAPIRSASQAEEE 491
Query: 465 MHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTE----LGDSCV 520
P + Q + H R+GT R LSRQ+TFD++T SR+SAY E V
Sbjct: 492 PSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHV 551
Query: 521 DMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEE---ELTDNRNRGRNKARYCAEGG 577
D + + G R+ + D E+ E R+R ++K RYC E
Sbjct: 552 DHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYC-EKD 610
Query: 578 GPVLGRNKNELEGWGRGVYIR 598
G V+ + +NE W R VYIR
Sbjct: 611 GEVISKKRNEAGEWNRDVYIR 631
>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
isoform 1 [Homo sapiens]
Length = 605
Score = 681 bits (1758), Expect = 0.0
Identities = 370/595 (62%), Positives = 431/595 (72%), Gaps = 55/595 (9%)
Query: 55 VRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPS 114
V GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ +
Sbjct: 14 VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
Query: 115 PGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQ 174
D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL EQ
Sbjct: 74 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
Query: 175 KLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASA------------------------ 210
+ +Q + SSKSG NSSSSLGD+V +R+ TPP+SA
Sbjct: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
Query: 211 ----------KQKQ----KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFL 256
K+K+ K TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFL
Sbjct: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
Query: 257 KHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTL 316
KHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
Query: 317 QLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEK 376
QLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++K
Sbjct: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
Query: 377 LAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAAS 436
LAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L S
Sbjct: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
Query: 437 PAPVSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGT 490
P SN QG + GDQ P+ A+ P + Q + H R+GT
Sbjct: 434 PTLASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT 490
Query: 491 LRALSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPARQG 546
R LSRQ+TFD++T SR+SAY E VD + + G R+
Sbjct: 491 SRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRES 550
Query: 547 SWEDEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
+ D E+ E R+R ++K RYC E G V+ + +NE W R VYIR
Sbjct: 551 RHRSRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 604
>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
isoform 7 [Homo sapiens]
Length = 612
Score = 681 bits (1756), Expect = 0.0
Identities = 369/592 (62%), Positives = 430/592 (72%), Gaps = 55/592 (9%)
Query: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ + D
Sbjct: 24 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 83
Query: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL EQ+ +
Sbjct: 84 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 143
Query: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASA--------------------------- 210
Q + SSKSG NSSSSLGD+V +R+ TPP+SA
Sbjct: 144 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 203
Query: 211 -------KQKQ----KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHR 259
K+K+ K TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 204 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 263
Query: 260 FDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLV 319
F+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 264 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 323
Query: 320 ALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQ 379
LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQ
Sbjct: 324 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 383
Query: 380 CPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAP 439
CPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L SP
Sbjct: 384 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 443
Query: 440 VSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRA 493
SN QG + GDQ P+ A+ P + Q + H R+GT R
Sbjct: 444 ASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 500
Query: 494 LSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWE 549
LSRQ+TFD++T SR+SAY E VD + + G R+
Sbjct: 501 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 560
Query: 550 DEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
+ D E+ E R+R ++K RYC E G V+ + +NE W R VYIR
Sbjct: 561 SRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 611
>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
isoform 3 [Homo sapiens]
Length = 606
Score = 681 bits (1756), Expect = 0.0
Identities = 369/592 (62%), Positives = 430/592 (72%), Gaps = 55/592 (9%)
Query: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ + D
Sbjct: 18 GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 77
Query: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL EQ+ +
Sbjct: 78 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 137
Query: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASA--------------------------- 210
Q + SSKSG NSSSSLGD+V +R+ TPP+SA
Sbjct: 138 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 197
Query: 211 -------KQKQ----KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHR 259
K+K+ K TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 198 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 257
Query: 260 FDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLV 319
F+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 258 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 317
Query: 320 ALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQ 379
LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQ
Sbjct: 318 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 377
Query: 380 CPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAP 439
CPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L SP
Sbjct: 378 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 437
Query: 440 VSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRA 493
SN QG + GDQ P+ A+ P + Q + H R+GT R
Sbjct: 438 ASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 494
Query: 494 LSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWE 549
LSRQ+TFD++T SR+SAY E VD + + G R+
Sbjct: 495 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 554
Query: 550 DEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598
+ D E+ E R+R ++K RYC E G V+ + +NE W R VYIR
Sbjct: 555 SRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 605
>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
Length = 520
Score = 629 bits (1621), Expect = e-180
Identities = 322/463 (69%), Positives = 376/463 (81%), Gaps = 16/463 (3%)
Query: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
Query: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
Query: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
Query: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242
KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
Query: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302
EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEV
Sbjct: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
Query: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362
QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
Query: 363 QSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNP 422
QSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SSTP P
Sbjct: 353 QSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTP 412
Query: 423 LLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASM 465
LL R + + AL+ P +S LQ + + E + E S+
Sbjct: 413 LLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSL 455
>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
isoform c [Homo sapiens]
Length = 502
Score = 626 bits (1615), Expect = e-179
Identities = 318/433 (73%), Positives = 366/433 (84%), Gaps = 7/433 (1%)
Query: 34 RKGRFKRSDGSTSSDTTSNSFV-RQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQ 92
R+ R KRSDGST TS SF+ RQGSA+SYTSRPSDSDVSLEEDREA+R+E E+QA Q
Sbjct: 11 RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 66
Query: 93 LEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKE 152
LE+AK+KPVAFAV+TNV Y + ++VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKE
Sbjct: 67 LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 126
Query: 153 GCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQ 212
GCE+GFIPSP++L+++R+ QEQK + R KS NSSSSLG++V+GT R TP ++AKQ
Sbjct: 127 GCEIGFIPSPLRLENIRIQQEQK--RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 184
Query: 213 KQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 272
KQK TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD
Sbjct: 185 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 244
Query: 273 ISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQL 332
ISLAKRSVLNNPSK IIERSNTRSSLAEVQSEIERIFELAR+LQLV LDADTINHPAQL
Sbjct: 245 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 304
Query: 333 SKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDEN 392
KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+ A++KLAQCPPEMFD+ILDEN
Sbjct: 305 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDEN 364
Query: 393 QLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGD 452
QLEDACEHL EYLEAYW+ATH SSTP PLL R + + AL+ P +S LQ + +
Sbjct: 365 QLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSN 424
Query: 453 QPLERATGEHASM 465
E + E S+
Sbjct: 425 HSTENSPIERRSL 437
>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
isoform a [Homo sapiens]
Length = 486
Score = 606 bits (1563), Expect = e-173
Identities = 303/408 (74%), Positives = 349/408 (85%), Gaps = 2/408 (0%)
Query: 58 GSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGD 117
GSA+SYTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + +
Sbjct: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75
Query: 118 EVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLR 177
+VPV AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK
Sbjct: 76 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK-- 133
Query: 178 QNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGP 237
+ R KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGP
Sbjct: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGP 193
Query: 238 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRS 297
SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRS
Sbjct: 194 SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRS 253
Query: 298 SLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIK 357
SLAEVQSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIK
Sbjct: 254 SLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIK 313
Query: 358 SRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSS 417
SRGKSQSKHLNVQ+ A++KLAQCPPEMFD+ILDENQLEDACEHL EYLEAYW+ATH SS
Sbjct: 314 SRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSS 373
Query: 418 TPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASM 465
TP PLL R + + AL+ P +S LQ + + E + E S+
Sbjct: 374 TPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSL 421
>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
isoform d [Homo sapiens]
Length = 458
Score = 538 bits (1385), Expect = e-153
Identities = 277/380 (72%), Positives = 321/380 (84%), Gaps = 16/380 (4%)
Query: 4 KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62
K + GP+ P+ ++ + R+ R KRSDGST TS SF+ RQGSA+S
Sbjct: 8 KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
Query: 63 YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122
YTSRPSDSDVSLEEDREA+R+E E+QA QLE+AK+KPVAFAV+TNV Y + ++VPV
Sbjct: 55 YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
Query: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182
AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK + R
Sbjct: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
Query: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242
KS NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
Query: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302
EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK IIERSNTRSSLAEV
Sbjct: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
Query: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362
QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
Query: 363 QSKHLNVQIAASEKLAQCPP 382
QSKHLNVQ+ A++KLAQCPP
Sbjct: 353 QSKHLNVQLVAADKLAQCPP 372
>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
[Homo sapiens]
Length = 484
Score = 532 bits (1370), Expect = e-151
Identities = 280/405 (69%), Positives = 319/405 (78%), Gaps = 28/405 (6%)
Query: 58 GSAESYTSRPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG 116
GSA+SYTSRPS DSDVSLEEDRE+ R+E E QA QLE+AK KPVAFAVRTNV Y
Sbjct: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
Query: 117 DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKL 176
+E PVQG + FE KDFLHIKEKY+NDWWIGRLVKEG ++ FIPSP +L+S+RL QEQK
Sbjct: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
Query: 177 RQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVG 236
R++ + SSL D+ G RR PP+ AKQKQK EHVPPYDVVPSMRP++LVG
Sbjct: 136 RRS---------GNPSSLSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVG 184
Query: 237 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTR 296
PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP K IIERS+ R
Sbjct: 185 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSAR 244
Query: 297 SSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLI 356
SS+AEVQSEIERIFELA++LQLV LDADTINHPAQL+KTSLAPIIV++K++SPKVLQRLI
Sbjct: 245 SSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLI 304
Query: 357 KSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPS 416
+SRGKSQ KHL VQ+ A +KL QCPPE FD+ILDENQLEDACEHLAEYLE YW+ATH P+
Sbjct: 305 RSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA 364
Query: 417 STPPNPLLNRTMATAALAASPAPVSNLQGPYLAS--GDQ--PLER 457
P L P+ + LQ L G++ PLER
Sbjct: 365 PGP------------GLLGPPSAIPGLQNQQLLGERGEEHSPLER 397
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 50.8 bits (120), Expect = 3e-06
Identities = 71/322 (22%), Positives = 129/322 (40%), Gaps = 38/322 (11%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG + F+ D LH+ +++WW R V E EVG IPS
Sbjct: 586 VRALFDYDKTKDSGLPSQG--LNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPS 643
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQK--QKSTEH 219
+++ + + ++ N SK+ D G + T AS + + E+
Sbjct: 644 KRRVEKKERARLKTVKFN----SKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEY 699
Query: 220 VPPYDVVPSM-----RPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADI 273
V Y+ V RP+I++GP + D + L +F + TR D
Sbjct: 700 VLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDY 753
Query: 274 SL---------AKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDAD 324
+ ++ + + +H IE + L + ++ + E+A + LD
Sbjct: 754 EVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVS 811
Query: 325 TINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEM 384
N +L L PI ++IK PK ++ +++ + + + KL Q E
Sbjct: 812 G-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEH 867
Query: 385 FDIILDENQLEDACEHLAEYLE 406
F I+ + LED + + +E
Sbjct: 868 FTAIVQGDTLEDIYNQVKQIIE 889
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/324 (19%), Positives = 127/324 (39%), Gaps = 49/324 (15%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG++ ++ D LH+ +++WW RLV E ++G IPS
Sbjct: 506 VRALFDYDRTRDSCLPSQGLSFSYG--DILHVINASDDEWWQARLVTPHGESEQIGVIPS 563
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVP 221
+++ + + ++ + + L D G AK + + +
Sbjct: 564 KKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYG---------AKNLKGQEDAIL 614
Query: 222 PYDVVPSM-----RPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL 275
Y+ V RP+I++GP + D + L H+F + TR D
Sbjct: 615 SYEPVTRQEIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRD--- 665
Query: 276 AKRSVLNNPSKHIIIERSNTRSSLAEVQ-------------SEIERIFELARTLQLVALD 322
+ ++ H ++ R + + + + I+ + +A + LD
Sbjct: 666 ---NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILD 722
Query: 323 ADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP 382
N +L + L PI ++IK PK ++ L++ + + N + KL Q
Sbjct: 723 VSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFG 778
Query: 383 EMFDIILDENQLEDACEHLAEYLE 406
E F I+ + LE+ + + +E
Sbjct: 779 EYFTAIVQGDSLEEIYNKIKQIIE 802
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 47.0 bits (110), Expect = 5e-05
Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 63/347 (18%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG++ ++ D LH+ +++WW RLV E ++G IPS
Sbjct: 169 VRALFDYDRTRDSCLPSQGLSFSYG--DILHVINASDDEWWQARLVTPHGESEQIGVIPS 226
Query: 162 PVK--------------------LDSLRLLQEQKLRQNRLGSS----KSGDN---SSSSL 194
+ ++S R ++ ++ + RL KS +N SS
Sbjct: 227 KKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQ 286
Query: 195 GDVVTGTRRPTPPASAKQKQKSTEHVP-PYDVVPSMRPIILVGPSLKGYEVTDMMQKALF 253
VT + +S Q+ + P + RP+I++GP + D + L
Sbjct: 287 EQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLI 340
Query: 254 DFLKHRFDGRI-SITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQ--------- 303
H+F + TR D + ++ H ++ R + + +
Sbjct: 341 SEFPHKFGSCVPHTTRPRRD------NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFND 394
Query: 304 ----SEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSR 359
+ I+ + +A + LD N +L + L PI ++IK PK ++ L++
Sbjct: 395 NLYGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMN 450
Query: 360 GKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLE 406
+ + N + KL Q E F I+ + LE+ + + +E
Sbjct: 451 RRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 46.6 bits (109), Expect = 7e-05
Identities = 67/333 (20%), Positives = 132/333 (39%), Gaps = 37/333 (11%)
Query: 92 QLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK 151
Q++ K V+ + Y+PS VP + + ++F+ D LH+ + + +WW + +
Sbjct: 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYR 394
Query: 152 EGCE-----VGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTP 206
EG E G +P Q+++ + + K + S +R
Sbjct: 395 EGDEDNQPLAGLVPGK------SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV 448
Query: 207 PASA-KQKQKSTEHVPPYDVVP-------SMRPIILVGPSLKGYEVTDMMQKALFDFLKH 258
+A K E + Y+ + RPIIL+GP G + +++ L + K
Sbjct: 449 LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKD 505
Query: 259 RFDGRI-SITRVTADISLA--------KRSVLNNPSKHIIIERSNTRSSLAEVQSEIERI 309
RF + TR D +A +++ + + IE +L + R
Sbjct: 506 RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQ 565
Query: 310 FELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS-QSKHLN 368
+ + L++L ++ L + L P I++I S + L+ L+ GK+ + + L
Sbjct: 566 VINSGKICLLSLRTQSLK---TLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELR 622
Query: 369 VQIAASEKLAQCPPEMFDIILDENQLEDACEHL 401
I + ++ Q FD + + L+ A + L
Sbjct: 623 EIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 46.6 bits (109), Expect = 7e-05
Identities = 71/338 (21%), Positives = 129/338 (38%), Gaps = 58/338 (17%)
Query: 100 PVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFI 159
P V+ + YNP + +P + + F + L I + + +WW VKEG G I
Sbjct: 215 PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLI 274
Query: 160 PSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEH 219
PS + L+E++ R + DNS G + + ++ + + +
Sbjct: 275 PS-------QFLEEKRKAFVR----RDWDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHE 323
Query: 220 VPPYDVVPSMRP-----IILVGP------SLKGYEV----TDMMQKALFDFLKHRFDGR- 263
+ Y+ V M P ++L+G SLK + T F K R D +
Sbjct: 324 IQIYEEVAKMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKD 383
Query: 264 ------ISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 317
+S + + ADI K +E +L ++I+ I E+ +T +
Sbjct: 384 GQAYKFVSRSEMEADIKAGK-----------YLEHGEYEGNL--YGTKIDSILEVVQTGR 430
Query: 318 LVALDADTINHPA--QLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS-------QSKHLN 368
LD +N A L + P +V+I + L+ + K+ + L
Sbjct: 431 TCILD---VNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLK 487
Query: 369 VQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLE 406
+ S ++ + FD+I+ + L+ A E L +E
Sbjct: 488 KTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIE 525
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 44.3 bits (103), Expect = 3e-04
Identities = 70/340 (20%), Positives = 128/340 (37%), Gaps = 52/340 (15%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ + +P QG + F+ D LH+ +++WW R V E EVG IPS
Sbjct: 586 VRALFDYDKTKDSGLPSQG--LNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPS 643
Query: 162 PVKLD---------------------SLRLLQEQKLRQNRLGSSKSGDNSSSSLGDV--- 197
+++ S +++ L + K+ D S D
Sbjct: 644 KRRVEKKERARLKTVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQH 703
Query: 198 VTGTRRPTPPASAKQKQKSTEHVP-PYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFL 256
VT + + Q++ + P V RP+I++GP + D + L
Sbjct: 704 VTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEF 757
Query: 257 KHRFDGRI-SITRVTADISL---------AKRSVLNNPSKHIIIERSNTRSSLAEVQSEI 306
+F + TR D + ++ + + +H IE + L + +
Sbjct: 758 PDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSV 815
Query: 307 ERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKH 366
+ + E+A + LD N +L L PI ++IK PK ++ +++ + +
Sbjct: 816 QSVREVAEKGKHCILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQ 871
Query: 367 LNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLE 406
+ KL Q E F I+ + LED + + +E
Sbjct: 872 ARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIE 911
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 43.1 bits (100), Expect = 7e-04
Identities = 67/314 (21%), Positives = 118/314 (37%), Gaps = 49/314 (15%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ S +P QG ++F+ D LH+ +++WW R V + E+G IPS
Sbjct: 438 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 495
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVP 221
+++ + + ++ N LGD GT K + + +
Sbjct: 496 KRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT---------KTLRGQEDLIL 546
Query: 222 PYDVVPSM-----RPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL 275
Y+ V RP+I++GP + D + L +F + TR D +
Sbjct: 547 SYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEV 600
Query: 276 AKRSVLNNPSKHIIIERSNTRSSLAEVQ-------------SEIERIFELARTLQLVALD 322
R H +I R + E + + ++ + +A + LD
Sbjct: 601 DGRDY------HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILD 654
Query: 323 ADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP 382
N +L L PI ++IK P+ L+ L++ + + + KL Q
Sbjct: 655 VSG-NAIKRLQVAQLYPIAIFIK---PRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFG 710
Query: 383 EMFDIILDENQLED 396
E F I+ + LED
Sbjct: 711 EYFTAIVQGDTLED 724
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 43.1 bits (100), Expect = 7e-04
Identities = 67/314 (21%), Positives = 118/314 (37%), Gaps = 49/314 (15%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVK---EGCEVGFIPS 161
VR Y+ S +P QG ++F+ D LH+ +++WW R V + E+G IPS
Sbjct: 23 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 80
Query: 162 PVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVP 221
+++ + + ++ N LGD GT K + + +
Sbjct: 81 KRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGT---------KTLRGQEDLIL 131
Query: 222 PYDVVPSM-----RPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADISL 275
Y+ V RP+I++GP + D + L +F + TR D +
Sbjct: 132 SYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEV 185
Query: 276 AKRSVLNNPSKHIIIERSNTRSSLAEVQ-------------SEIERIFELARTLQLVALD 322
R H +I R + E + + ++ + +A + LD
Sbjct: 186 DGRDY------HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILD 239
Query: 323 ADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP 382
N +L L PI ++IK P+ L+ L++ + + + KL Q
Sbjct: 240 VSG-NAIKRLQVAQLYPIAIFIK---PRSLEPLMEMNKRLTEEQAKKTYDRAIKLEQEFG 295
Query: 383 EMFDIILDENQLED 396
E F I+ + LED
Sbjct: 296 EYFTAIVQGDTLED 309
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 40.8 bits (94), Expect = 0.004
Identities = 62/301 (20%), Positives = 116/301 (38%), Gaps = 61/301 (20%)
Query: 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQKLRQNRL 181
A++F D LH+ + + +WW R V E ++GFIPS ++ ++ +RL
Sbjct: 494 ALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRV--------ERREWSRL 545
Query: 182 GSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSM-----RPIILVG 236
+ G +S S Q + V Y+ V M RPII++G
Sbjct: 546 KAKDWGSSSGS---------------------QGREDSVLSYETVTQMEVHYARPIIILG 584
Query: 237 PSLKGYEVTDMMQKALFDF-----------LKHRFDGRISITRVTADISLAKRSVLNNPS 285
P+ K D++ + F ++ DGR ++ + +
Sbjct: 585 PT-KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGR------DYHFVSSREKMEKDIQ 637
Query: 286 KHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIK 345
H IE S L + ++ + E+A + LD + N +L L PI ++I+
Sbjct: 638 AHKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 694
Query: 346 ITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYL 405
P+ L+ +++ + + + KL Q E F I++ + E+ + +
Sbjct: 695 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 751
Query: 406 E 406
E
Sbjct: 752 E 752
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 40.8 bits (94), Expect = 0.004
Identities = 62/301 (20%), Positives = 116/301 (38%), Gaps = 61/301 (20%)
Query: 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQKLRQNRL 181
A++F D LH+ + + +WW R V E ++GFIPS ++ ++ +RL
Sbjct: 448 ALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRV--------ERREWSRL 499
Query: 182 GSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSM-----RPIILVG 236
+ G +S S Q + V Y+ V M RPII++G
Sbjct: 500 KAKDWGSSSGS---------------------QGREDSVLSYETVTQMEVHYARPIIILG 538
Query: 237 PSLKGYEVTDMMQKALFDF-----------LKHRFDGRISITRVTADISLAKRSVLNNPS 285
P+ K D++ + F ++ DGR ++ + +
Sbjct: 539 PT-KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGR------DYHFVSSREKMEKDIQ 591
Query: 286 KHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIK 345
H IE S L + ++ + E+A + LD + N +L L PI ++I+
Sbjct: 592 AHKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR 648
Query: 346 ITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYL 405
P+ L+ +++ + + + KL Q E F I++ + E+ + +
Sbjct: 649 ---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 705
Query: 406 E 406
E
Sbjct: 706 E 706
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 40.0 bits (92), Expect = 0.006
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLV-KEGCEVGFIPSP 162
VR Y+P+ D +P + I F D + I K +++WW G+L + G IPSP
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 646
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 40.0 bits (92), Expect = 0.006
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLV-KEGCEVGFIPSP 162
VR Y+P+ D +P + I F D + I K +++WW G+L + G IPSP
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 652
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 40.0 bits (92), Expect = 0.006
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 105 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLV-KEGCEVGFIPSP 162
VR Y+P+ D +P + I F D + I K +++WW G+L + G IPSP
Sbjct: 617 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 675
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 40.0 bits (92), Expect = 0.006
Identities = 39/148 (26%), Positives = 54/148 (36%), Gaps = 9/148 (6%)
Query: 419 PPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGL 478
PP+PL + + + S A +S+ GP L + P T A E P PP
Sbjct: 1557 PPSPLSEASSGYFSHSVSTATLSDALGPGLDAAAPPGSMPTAPEAEP-EAPISHPPPPTA 1615
Query: 479 YPSSHPPGRAGTLRALSRQDTFDADTPGS----RNSAYTELGDSCVDMETDPSEGPGLGD 534
P+ PPG + + +A PGS R +EL + DP PG
Sbjct: 1616 VPAEEPPGPQQLVSPGRERPDLEAPAPGSPFRVRRVRASELRSFSRMLAGDPGCSPGAEG 1675
Query: 535 ----PAGGGTPPARQGSWEDEEEDYEEE 558
P GG A DE ++ E
Sbjct: 1676 NAPAPGAGGQALASDSEEADEVPEWLRE 1703
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,576,180
Number of Sequences: 37866
Number of extensions: 1432638
Number of successful extensions: 6465
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 155
Number of HSP's that attempted gapping in prelim test: 6142
Number of HSP's gapped (non-prelim): 434
length of query: 598
length of database: 18,247,518
effective HSP length: 108
effective length of query: 490
effective length of database: 14,157,990
effective search space: 6937415100
effective search space used: 6937415100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.