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Search of human proteins with 40316928
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
[Homo sapiens]
(484 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [... 974 0.0
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i... 622 e-178
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i... 602 e-172
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i... 602 e-172
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ... 556 e-158
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ... 537 e-153
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i... 537 e-153
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i... 533 e-151
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ... 533 e-151
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ... 533 e-151
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ... 533 e-151
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ... 533 e-151
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i... 533 e-151
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i... 532 e-151
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ... 517 e-147
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i... 502 e-142
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 54 4e-07
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 51 2e-06
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 46 9e-05
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 46 9e-05
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 45 1e-04
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 45 1e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 42 0.001
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 42 0.001
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 41 0.002
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 41 0.002
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 41 0.002
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 40 0.004
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 40 0.004
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 40 0.005
>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
[Homo sapiens]
Length = 484
Score = 974 bits (2518), Expect = 0.0
Identities = 484/484 (100%), Positives = 484/484 (100%)
Query: 1 MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV 60
MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV
Sbjct: 1 MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV 60
Query: 61 AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPS 120
AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPS
Sbjct: 61 AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPS 120
Query: 121 PQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPV 180
PQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPV
Sbjct: 121 PQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPV 180
Query: 181 VLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIER 240
VLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIER
Sbjct: 181 VLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIER 240
Query: 241 SSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVL 300
SSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVL
Sbjct: 241 SSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVL 300
Query: 301 QRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRAT 360
QRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRAT
Sbjct: 301 QRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRAT 360
Query: 361 HHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQR 420
HHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQR
Sbjct: 361 HHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQR 420
Query: 421 SSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWP 480
SSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWP
Sbjct: 421 SSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWP 480
Query: 481 KDSY 484
KDSY
Sbjct: 481 KDSY 484
>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
isoform a [Homo sapiens]
Length = 486
Score = 622 bits (1604), Expect = e-178
Identities = 341/489 (69%), Positives = 380/489 (77%), Gaps = 33/489 (6%)
Query: 1 MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV 60
MYD+ Y+ G EDSEAGSADSYTSRPS DSDVSLEEDRE+ R+E E QA QLERAK KPV
Sbjct: 1 MYDNLYLHGIEDSEAGSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPV 59
Query: 61 AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPS 120
AFAV+TNVSYCG LDE+ PV + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPS
Sbjct: 60 AFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPS 119
Query: 121 PQRLESIRLKQEQKARR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPY 171
P RLE+IR++QEQK R SGN SS L ++ G R+ P S AKQKQK EH+PPY
Sbjct: 120 PLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPY 179
Query: 172 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNN 231
DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNN
Sbjct: 180 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNN 239
Query: 232 PGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVF 291
P KR IIERS+ RSS+AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV
Sbjct: 240 PSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVH 299
Query: 292 VKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAE 351
VKVSSPKVLQRLI+SRGKSQ KHL VQ++A DKL QCPPE FDVILDENQLEDACEHL E
Sbjct: 300 VKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGE 359
Query: 352 YLEVYWRATHHPAPGP--GLLGP----------PSAIPGLQNQQLL-GERGEEHSPLERD 398
YLE YWRATH + P LLG P+AI GLQ+Q++ E+SP+ER
Sbjct: 360 YLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERR 419
Query: 399 SLMPSD-----EASESSRQAWTGSSQRSSRH---LEEDYADAYQDLYQPHRQHTSGLPSA 450
SLM SD E + SR + SSQ S H +EEDY D+YQD Y+PHR G P
Sbjct: 420 SLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNR--GSPGG 477
Query: 451 NGHDPQDRL 459
HD + RL
Sbjct: 478 YSHDSRHRL 486
>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
isoform c [Homo sapiens]
Length = 502
Score = 602 bits (1551), Expect = e-172
Identities = 331/474 (69%), Positives = 368/474 (77%), Gaps = 33/474 (6%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ R+E E QA QLERAK KPVAFAV+TNVSYCG LD
Sbjct: 32 GSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALD 90
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
E+ PV + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPSP RLE+IR++QEQK
Sbjct: 91 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKR 150
Query: 136 RR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPS 186
R SGN SS L ++ G R+ P S AKQKQK EH+PPYDVVPSMRPVVLVGPS
Sbjct: 151 GRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 210
Query: 187 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246
LKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP KR IIERS+ RSS
Sbjct: 211 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS 270
Query: 247 IAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRS 306
+AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV VKVSSPKVLQRLI+S
Sbjct: 271 LAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKS 330
Query: 307 RGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPG 366
RGKSQ KHL VQ++A DKL QCPPE FDVILDENQLEDACEHL EYLE YWRATH +
Sbjct: 331 RGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSST 390
Query: 367 P--GLLGP----------PSAIPGLQNQQLL-GERGEEHSPLERDSLMPSD-----EASE 408
P LLG P+AI GLQ+Q++ E+SP+ER SLM SD E +
Sbjct: 391 PMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERAR 450
Query: 409 SSRQAWTGSSQRSSRH---LEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRL 459
SR + SSQ S H +EEDY D+YQD Y+PHR G P HD + RL
Sbjct: 451 KSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNR--GSPGGYSHDSRHRL 502
>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
isoform b [Homo sapiens]
Length = 520
Score = 602 bits (1551), Expect = e-172
Identities = 331/474 (69%), Positives = 368/474 (77%), Gaps = 33/474 (6%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ R+E E QA QLERAK KPVAFAV+TNVSYCG LD
Sbjct: 50 GSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALD 108
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
E+ PV + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPSP RLE+IR++QEQK
Sbjct: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKR 168
Query: 136 RR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPS 186
R SGN SS L ++ G R+ P S AKQKQK EH+PPYDVVPSMRPVVLVGPS
Sbjct: 169 GRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
Query: 187 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246
LKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP KR IIERS+ RSS
Sbjct: 229 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS 288
Query: 247 IAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRS 306
+AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV VKVSSPKVLQRLI+S
Sbjct: 289 LAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKS 348
Query: 307 RGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPG 366
RGKSQ KHL VQ++A DKL QCPPE FDVILDENQLEDACEHL EYLE YWRATH +
Sbjct: 349 RGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSST 408
Query: 367 P--GLLGP----------PSAIPGLQNQQLL-GERGEEHSPLERDSLMPSD-----EASE 408
P LLG P+AI GLQ+Q++ E+SP+ER SLM SD E +
Sbjct: 409 PMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERAR 468
Query: 409 SSRQAWTGSSQRSSRH---LEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRL 459
SR + SSQ S H +EEDY D+YQD Y+PHR G P HD + RL
Sbjct: 469 KSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNR--GSPGGYSHDSRHRL 520
>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
isoform 5 [Homo sapiens]
Length = 622
Score = 556 bits (1434), Expect = e-158
Identities = 312/527 (59%), Positives = 367/527 (69%), Gaps = 60/527 (11%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 72 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 130
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 131 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 190
Query: 136 RRS---------GNPSSLSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVG 184
++ + SSL DI +R+S PPS AKQKQK EH PPYDVVPSMRPVVLVG
Sbjct: 191 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQKQKSTEHTPPYDVVPSMRPVVLVG 250
Query: 185 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSAR 244
PSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD+SLAKRSVLNNP K IIERS+ R
Sbjct: 251 PSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTR 310
Query: 245 SSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLI 304
SS+AEVQSEIERIFELA++LQLVVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI
Sbjct: 311 SSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLI 370
Query: 305 RSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA 364
+SRGKSQ KHL VQM+A DKL QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+
Sbjct: 371 KSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPS 430
Query: 365 ---PGPGLLGPPSAIPGLQNQQLL-----GERGEEHS-------------------PLER 397
P P LL A L L G +G++ + P+++
Sbjct: 431 SSLPNP-LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKK 489
Query: 398 DSLMPSDEASESSRQAWTG-------------SSQRSSRHLE--EDYADAYQDLYQPHRQ 442
S A + ++ T R S ++E EDY+ + D Y HR
Sbjct: 490 SQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRD 549
Query: 443 H-----TSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDSY 484
H T G + + R D E +H++ N QR+R KD Y
Sbjct: 550 HNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRY 596
>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
isoform 8 [Homo sapiens]
Length = 608
Score = 537 bits (1383), Expect = e-153
Identities = 309/541 (57%), Positives = 365/541 (67%), Gaps = 74/541 (13%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 44 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 102
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 103 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 162
Query: 136 RRS---------GNPSSLSDI--GNRRSPPPSL-AKQKQKQ-------------AEHVPP 170
++ + SSL DI +R+S PPS AK +Q EH PP
Sbjct: 163 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPP 222
Query: 171 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLN 230
YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD+SLAKRSVLN
Sbjct: 223 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLN 282
Query: 231 NPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIV 290
NP K IIERS+ RSS+AEVQSEIERIFELA++LQLVVLDADTINHPAQL+KTSLAPIIV
Sbjct: 283 NPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIV 342
Query: 291 FVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLA 350
+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL QCPPE FDVILDENQLEDACEHLA
Sbjct: 343 YVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLA 402
Query: 351 EYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQLL-----GERGEEHS--------- 393
+YLE YW+ATH P+ P P LL A L L G +G++ +
Sbjct: 403 DYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSA 461
Query: 394 ----------PLERDSLMPSDEASESSRQAWTG-------------SSQRSSRHLE--ED 428
P+++ S A + ++ T R S ++E ED
Sbjct: 462 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKED 521
Query: 429 YADAYQDLYQPHRQH-----TSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDS 483
Y+ + D Y HR H T G + + R D E +H++ N QR+R KD
Sbjct: 522 YSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 581
Query: 484 Y 484
Y
Sbjct: 582 Y 582
>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
isoform 4 [Homo sapiens]
Length = 636
Score = 537 bits (1383), Expect = e-153
Identities = 309/541 (57%), Positives = 365/541 (67%), Gaps = 74/541 (13%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 72 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 130
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 131 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 190
Query: 136 RRS---------GNPSSLSDI--GNRRSPPPSL-AKQKQKQ-------------AEHVPP 170
++ + SSL DI +R+S PPS AK +Q EH PP
Sbjct: 191 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPP 250
Query: 171 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLN 230
YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD+SLAKRSVLN
Sbjct: 251 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLN 310
Query: 231 NPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIV 290
NP K IIERS+ RSS+AEVQSEIERIFELA++LQLVVLDADTINHPAQL+KTSLAPIIV
Sbjct: 311 NPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIV 370
Query: 291 FVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLA 350
+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL QCPPE FDVILDENQLEDACEHLA
Sbjct: 371 YVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLA 430
Query: 351 EYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQLL-----GERGEEHS--------- 393
+YLE YW+ATH P+ P P LL A L L G +G++ +
Sbjct: 431 DYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSA 489
Query: 394 ----------PLERDSLMPSDEASESSRQAWTG-------------SSQRSSRHLE--ED 428
P+++ S A + ++ T R S ++E ED
Sbjct: 490 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKED 549
Query: 429 YADAYQDLYQPHRQH-----TSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDS 483
Y+ + D Y HR H T G + + R D E +H++ N QR+R KD
Sbjct: 550 YSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 609
Query: 484 Y 484
Y
Sbjct: 610 Y 610
>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
isoform 7 [Homo sapiens]
Length = 612
Score = 533 bits (1373), Expect = e-151
Identities = 312/565 (55%), Positives = 367/565 (64%), Gaps = 98/565 (17%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 24 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 82
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 83 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 142
Query: 136 -------------------------RRSGNPSSLSDI-------------GNRRSPPPSL 157
R+S PSS DI N RSP PS
Sbjct: 143 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSA 202
Query: 158 -------AKQKQ----KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 206
+K+K+ K+ EH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 203 NSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 262
Query: 207 RFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQL 266
RF+GRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFELA++LQL
Sbjct: 263 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 322
Query: 267 VVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLV 326
VVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL
Sbjct: 323 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 382
Query: 327 QCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQ 383
QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+ P P LL A L
Sbjct: 383 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSP 441
Query: 384 LL-----GERGEEHS-------------------PLERDSLMPSDEASESSRQAWTG--- 416
L G +G++ + P+++ S A + ++ T
Sbjct: 442 TLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGL 501
Query: 417 ----------SSQRSSRHLE--EDYADAYQDLYQPHRQH-----TSGLPSANGHDPQDRL 459
R S ++E EDY+ + D Y HR H T G + + R
Sbjct: 502 SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRS 561
Query: 460 LAQDSEHNHSDRNWQRNRPWPKDSY 484
D E +H++ N QR+R KD Y
Sbjct: 562 RDVDREQDHNECNKQRSRHKSKDRY 586
>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
isoform 6 [Homo sapiens]
Length = 632
Score = 533 bits (1373), Expect = e-151
Identities = 312/565 (55%), Positives = 367/565 (64%), Gaps = 98/565 (17%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 44 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 102
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 103 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 162
Query: 136 -------------------------RRSGNPSSLSDI-------------GNRRSPPPSL 157
R+S PSS DI N RSP PS
Sbjct: 163 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSA 222
Query: 158 -------AKQKQ----KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 206
+K+K+ K+ EH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 223 NSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 282
Query: 207 RFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQL 266
RF+GRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFELA++LQL
Sbjct: 283 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 342
Query: 267 VVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLV 326
VVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL
Sbjct: 343 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 402
Query: 327 QCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQ 383
QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+ P P LL A L
Sbjct: 403 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSP 461
Query: 384 LL-----GERGEEHS-------------------PLERDSLMPSDEASESSRQAWTG--- 416
L G +G++ + P+++ S A + ++ T
Sbjct: 462 TLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGL 521
Query: 417 ----------SSQRSSRHLE--EDYADAYQDLYQPHRQH-----TSGLPSANGHDPQDRL 459
R S ++E EDY+ + D Y HR H T G + + R
Sbjct: 522 SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRS 581
Query: 460 LAQDSEHNHSDRNWQRNRPWPKDSY 484
D E +H++ N QR+R KD Y
Sbjct: 582 RDVDREQDHNECNKQRSRHKSKDRY 606
>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
isoform 3 [Homo sapiens]
Length = 606
Score = 533 bits (1373), Expect = e-151
Identities = 312/565 (55%), Positives = 367/565 (64%), Gaps = 98/565 (17%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 18 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 76
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 77 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 136
Query: 136 -------------------------RRSGNPSSLSDI-------------GNRRSPPPSL 157
R+S PSS DI N RSP PS
Sbjct: 137 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSA 196
Query: 158 -------AKQKQ----KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 206
+K+K+ K+ EH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 197 NSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 256
Query: 207 RFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQL 266
RF+GRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFELA++LQL
Sbjct: 257 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 316
Query: 267 VVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLV 326
VVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL
Sbjct: 317 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 376
Query: 327 QCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQ 383
QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+ P P LL A L
Sbjct: 377 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSP 435
Query: 384 LL-----GERGEEHS-------------------PLERDSLMPSDEASESSRQAWTG--- 416
L G +G++ + P+++ S A + ++ T
Sbjct: 436 TLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGL 495
Query: 417 ----------SSQRSSRHLE--EDYADAYQDLYQPHRQH-----TSGLPSANGHDPQDRL 459
R S ++E EDY+ + D Y HR H T G + + R
Sbjct: 496 SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRS 555
Query: 460 LAQDSEHNHSDRNWQRNRPWPKDSY 484
D E +H++ N QR+R KD Y
Sbjct: 556 RDVDREQDHNECNKQRSRHKSKDRY 580
>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
isoform 2 [Homo sapiens]
Length = 660
Score = 533 bits (1373), Expect = e-151
Identities = 312/565 (55%), Positives = 367/565 (64%), Gaps = 98/565 (17%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 72 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 130
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 131 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 190
Query: 136 -------------------------RRSGNPSSLSDI-------------GNRRSPPPSL 157
R+S PSS DI N RSP PS
Sbjct: 191 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSA 250
Query: 158 -------AKQKQ----KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 206
+K+K+ K+ EH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 251 NSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 310
Query: 207 RFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQL 266
RF+GRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFELA++LQL
Sbjct: 311 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 370
Query: 267 VVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLV 326
VVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL
Sbjct: 371 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 430
Query: 327 QCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQ 383
QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+ P P LL A L
Sbjct: 431 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSP 489
Query: 384 LL-----GERGEEHS-------------------PLERDSLMPSDEASESSRQAWTG--- 416
L G +G++ + P+++ S A + ++ T
Sbjct: 490 TLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGL 549
Query: 417 ----------SSQRSSRHLE--EDYADAYQDLYQPHRQH-----TSGLPSANGHDPQDRL 459
R S ++E EDY+ + D Y HR H T G + + R
Sbjct: 550 SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRS 609
Query: 460 LAQDSEHNHSDRNWQRNRPWPKDSY 484
D E +H++ N QR+R KD Y
Sbjct: 610 RDVDREQDHNECNKQRSRHKSKDRY 634
>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
isoform 1 [Homo sapiens]
Length = 605
Score = 533 bits (1373), Expect = e-151
Identities = 312/565 (55%), Positives = 367/565 (64%), Gaps = 98/565 (17%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY +
Sbjct: 17 GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 75
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
++ PV G ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 76 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 135
Query: 136 -------------------------RRSGNPSSLSDI-------------GNRRSPPPSL 157
R+S PSS DI N RSP PS
Sbjct: 136 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSA 195
Query: 158 -------AKQKQ----KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 206
+K+K+ K+ EH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 196 NSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 255
Query: 207 RFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQL 266
RF+GRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFELA++LQL
Sbjct: 256 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 315
Query: 267 VVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLV 326
VVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL
Sbjct: 316 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 375
Query: 327 QCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQ 383
QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+ P P LL A L
Sbjct: 376 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSP 434
Query: 384 LL-----GERGEEHS-------------------PLERDSLMPSDEASESSRQAWTG--- 416
L G +G++ + P+++ S A + ++ T
Sbjct: 435 TLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGL 494
Query: 417 ----------SSQRSSRHLE--EDYADAYQDLYQPHRQH-----TSGLPSANGHDPQDRL 459
R S ++E EDY+ + D Y HR H T G + + R
Sbjct: 495 SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRS 554
Query: 460 LAQDSEHNHSDRNWQRNRPWPKDSY 484
D E +H++ N QR+R KD Y
Sbjct: 555 RDVDREQDHNECNKQRSRHKSKDRY 579
>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
isoform 3 [Homo sapiens]
Length = 478
Score = 533 bits (1372), Expect = e-151
Identities = 283/420 (67%), Positives = 325/420 (77%), Gaps = 33/420 (7%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSA+SYTSRPS DSDVSLEEDRE+ R+E E QA QLE+AK KPVAFAVRTNV Y
Sbjct: 58 GSAESYTSRPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG 116
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
+E PVQG + FE KDFLHIKEKY+NDWWIGRLVKEG ++ FIPSP +L+S+RL QEQK
Sbjct: 117 DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKL 176
Query: 136 RRS---------GNPSSLSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVG 184
R++ + SSL D+ G RR PP+ AKQKQK EHVPPYDVVPSMRP++LVG
Sbjct: 177 RQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVG 236
Query: 185 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSAR 244
PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP K IIERS+ R
Sbjct: 237 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTR 296
Query: 245 SSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLI 304
SS+AEVQSEIERIFELA++LQLV LDADTINHPAQL+KTSLAPIIV++K++SPKVLQRLI
Sbjct: 297 SSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLI 356
Query: 305 RSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA 364
+SRGKSQ KHL VQ+ A +KL QCPPE FD+ILDENQLEDACEHLAEYLE YW+ATH P+
Sbjct: 357 KSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPS 416
Query: 365 PGP------------GLLGPPSAIPGLQNQQLLGER-------GEEHSPLERDSLMPSDE 405
P L P+ + LQ Q L R G E S +R S++P ++
Sbjct: 417 STPPNPLLNRTMATAALAASPAPVSNLQVQVLTSLRRNLGFWGGLESS--QRGSVVPQEQ 474
>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
isoform 1 [Homo sapiens]
Length = 598
Score = 532 bits (1370), Expect = e-151
Identities = 280/405 (69%), Positives = 319/405 (78%), Gaps = 28/405 (6%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSA+SYTSRPS DSDVSLEEDRE+ R+E E QA QLE+AK KPVAFAVRTNV Y
Sbjct: 58 GSAESYTSRPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG 116
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
+E PVQG + FE KDFLHIKEKY+NDWWIGRLVKEG ++ FIPSP +L+S+RL QEQK
Sbjct: 117 DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKL 176
Query: 136 RRS---------GNPSSLSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVG 184
R++ + SSL D+ G RR PP+ AKQKQK EHVPPYDVVPSMRP++LVG
Sbjct: 177 RQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVG 236
Query: 185 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSAR 244
PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP K IIERS+ R
Sbjct: 237 PSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTR 296
Query: 245 SSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLI 304
SS+AEVQSEIERIFELA++LQLV LDADTINHPAQL+KTSLAPIIV++K++SPKVLQRLI
Sbjct: 297 SSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLI 356
Query: 305 RSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA 364
+SRGKSQ KHL VQ+ A +KL QCPPE FD+ILDENQLEDACEHLAEYLE YW+ATH P+
Sbjct: 357 KSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPS 416
Query: 365 PGP------------GLLGPPSAIPGLQNQQLLGERGEEHSPLER 397
P L P+ + LQ L G++ PLER
Sbjct: 417 STPPNPLLNRTMATAALAASPAPVSNLQGPYLAS--GDQ--PLER 457
>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
isoform d [Homo sapiens]
Length = 458
Score = 517 bits (1332), Expect = e-147
Identities = 294/461 (63%), Positives = 326/461 (70%), Gaps = 69/461 (14%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSADSYTSRPS DSDVSLEEDRE+ R+E E QA QLERAK KPVAFAV+TNVSYCG LD
Sbjct: 50 GSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALD 108
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
E+ PV + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPSP RLE+IR++QEQK
Sbjct: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKR 168
Query: 136 RR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPS 186
R SGN SS L ++ G R+ P S AKQKQK EH+PPYDVVPSMRPVVLVGPS
Sbjct: 169 GRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
Query: 187 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246
LKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP KR IIERS+ RSS
Sbjct: 229 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS 288
Query: 247 IAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRS 306
+AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV VKVSSPKVLQRLI+S
Sbjct: 289 LAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKS 348
Query: 307 RGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPG 366
RGKSQ KHL VQ++A DKL QCPP R H
Sbjct: 349 RGKSQSKHLNVQLVAADKLAQCPPSQ-------------------------RMRH----- 378
Query: 367 PGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSD-----EASESSRQAWTGSSQRS 421
E+SP+ER SLM SD E + SR + SSQ S
Sbjct: 379 -------------------SNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHS 419
Query: 422 SRH---LEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRL 459
H +EEDY D+YQD Y+PHR G P HD + RL
Sbjct: 420 RDHYPLVEEDYPDSYQDTYKPHRNR--GSPGGYSHDSRHRL 458
>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
isoform 2 [Homo sapiens]
Length = 523
Score = 502 bits (1293), Expect = e-142
Identities = 278/465 (59%), Positives = 322/465 (69%), Gaps = 78/465 (16%)
Query: 16 GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75
GSA+SYTSRPS DSDVSLEEDRE+ R+E E QA QLE+AK KPVAFAVRTNV Y
Sbjct: 58 GSAESYTSRPS-DSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG 116
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135
+E PVQG + FE KDFLHIKEKY+NDWWIGRLVKEG ++ FIPSP +L+S+RL QEQK
Sbjct: 117 DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKL 176
Query: 136 RRS---------GNPSSLSDI--GNRRSPPPSLAKQKQ---------------------- 162
R++ + SSL D+ G RR PP+ +
Sbjct: 177 RQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQS 236
Query: 163 -----------------------KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKA 199
K+ EHVPPYDVVPSMRP++LVGPSLKGYEVTDMMQKA
Sbjct: 237 GSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKA 296
Query: 200 LFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFE 259
LFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP K IIERS+ RSS+AEVQSEIERIFE
Sbjct: 297 LFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFE 356
Query: 260 LAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQM 319
LA++LQLV LDADTINHPAQL+KTSLAPIIV++K++SPKVLQRLI+SRGKSQ KHL VQ+
Sbjct: 357 LARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQI 416
Query: 320 MAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPGP------------ 367
A +KL QCPPE FD+ILDENQLEDACEHLAEYLE YW+ATH P+ P
Sbjct: 417 AASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATA 476
Query: 368 GLLGPPSAIPGLQNQQLLGER-------GEEHSPLERDSLMPSDE 405
L P+ + LQ Q L R G E S +R S++P ++
Sbjct: 477 ALAASPAPVSNLQVQVLTSLRRNLGFWGGLESS--QRGSVVPQEQ 519
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 53.5 bits (127), Expect = 4e-07
Identities = 75/312 (24%), Positives = 125/312 (40%), Gaps = 36/312 (11%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGD---IAFIPS 120
VR Y D P QG ++F D LH+ ++WW RLV G+ I IPS
Sbjct: 506 VRALFDYDRTRDSCLPSQG--LSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPS 563
Query: 121 PQRLES---IRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSM 177
+R+E RLK + R+G S D S AK + Q + + Y+ V
Sbjct: 564 KKRVEKKERARLKTVKFHARTGMIESNRDFPG-LSDDYYGAKNLKGQEDAILSYEPVTRQ 622
Query: 178 -----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTAD---------LS 222
RPV+++GP + D + L H+F + TR D
Sbjct: 623 EIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFV 676
Query: 223 LAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAK 282
+++ + + IE ++ + I+ + +A+ + +LD N +L +
Sbjct: 677 VSREQMEKDIQDNKFIEAGQFNDNL--YGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQ 733
Query: 283 TSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQL 342
L PI +F+K S + L + R + Q + + M KL Q E F I+ + L
Sbjct: 734 AQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAM---KLEQEFGEYFTAIVQGDSL 790
Query: 343 EDACEHLAEYLE 354
E+ + + +E
Sbjct: 791 EEIYNKIKQIIE 802
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 51.2 bits (121), Expect = 2e-06
Identities = 75/317 (23%), Positives = 123/317 (38%), Gaps = 39/317 (12%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVK---EGGDIAFIPS 120
VR Y D P QG +NF+ D LH+ ++WW R V E ++ IPS
Sbjct: 586 VRALFDYDKTKDSGLPSQG--LNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPS 643
Query: 121 PQRLES---IRLKQ---EQKARRSGN-PSSLSDIGNRR--SPPPSLAKQKQKQAEHVPPY 171
+R+E RLK K R G P + G + S + Q E+V Y
Sbjct: 644 KRRVEKKERARLKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSY 703
Query: 172 DVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADLSLAK 225
+ V RPV+++GP + D + L +F + TR D +
Sbjct: 704 EPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDG 757
Query: 226 RSVLNNPGKRTIIERSSARSSIAEV--------QSEIERIFELAKSLQLVVLDADTINHP 277
R + R +E+ E + ++ + E+A+ + +LD N
Sbjct: 758 RD-YHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSG-NAI 815
Query: 278 AQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVIL 337
+L L PI +F+K S + + + + + Q + + M KL Q E F I+
Sbjct: 816 KRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAM---KLEQEFTEHFTAIV 872
Query: 338 DENQLEDACEHLAEYLE 354
+ LED + + +E
Sbjct: 873 QGDTLEDIYNQVKQIIE 889
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 45.8 bits (107), Expect = 9e-05
Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 44/295 (14%)
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV---KEGGDIAFIPSPQRLESIRLKQE 132
++C ++F D LH+ + +WW R V E DI FIPS +R+E
Sbjct: 486 KDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE------- 538
Query: 133 QKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSM-----RPVVLVGPSL 187
RR + D G+ + Q + + V Y+ V M RP++++GP+
Sbjct: 539 ---RREWSRLKAKDWGS--------SSGSQGREDSVLSYETVTQMEVHYARPIIILGPT- 586
Query: 188 KGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246
D L +F + TR + + R + + + A
Sbjct: 587 -----KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKF 641
Query: 247 IAEVQ-------SEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKV 299
I Q + ++ + E+A+ + +LD + N +L L PI +F++ P+
Sbjct: 642 IEAGQYNSHLYGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR---PRS 697
Query: 300 LQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
L+ ++ + + KL Q E F I++ + E+ + +E
Sbjct: 698 LENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 752
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 45.8 bits (107), Expect = 9e-05
Identities = 60/295 (20%), Positives = 112/295 (37%), Gaps = 44/295 (14%)
Query: 76 EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV---KEGGDIAFIPSPQRLESIRLKQE 132
++C ++F D LH+ + +WW R V E DI FIPS +R+E
Sbjct: 440 KDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE------- 492
Query: 133 QKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSM-----RPVVLVGPSL 187
RR + D G+ + Q + + V Y+ V M RP++++GP+
Sbjct: 493 ---RREWSRLKAKDWGS--------SSGSQGREDSVLSYETVTQMEVHYARPIIILGPT- 540
Query: 188 KGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246
D L +F + TR + + R + + + A
Sbjct: 541 -----KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKF 595
Query: 247 IAEVQ-------SEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKV 299
I Q + ++ + E+A+ + +LD + N +L L PI +F++ P+
Sbjct: 596 IEAGQYNSHLYGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR---PRS 651
Query: 300 LQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
L+ ++ + + KL Q E F I++ + E+ + +E
Sbjct: 652 LENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 706
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 45.4 bits (106), Expect = 1e-04
Identities = 76/343 (22%), Positives = 128/343 (37%), Gaps = 66/343 (19%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGD---IAFIPS 120
VR Y D P QG ++F D LH+ ++WW RLV G+ I IPS
Sbjct: 169 VRALFDYDRTRDSCLPSQG--LSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPS 226
Query: 121 PQRLES---IRLKQEQKARRSGNPSSLSDIGNRRSPPPSLA------KQKQKQAEH---- 167
+R+E RLK + R+G S I +R L+ K K+ A+
Sbjct: 227 KKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQ 286
Query: 168 ---------------------VPPYDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALF 201
+ Y+ V RPV+++GP + D + L
Sbjct: 287 EQGVTSNTSDSESSSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLI 340
Query: 202 DFLKHRFDGRI-SITRVTAD---------LSLAKRSVLNNPGKRTIIERSSARSSIAEVQ 251
H+F + TR D +++ + + IE ++
Sbjct: 341 SEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNL--YG 398
Query: 252 SEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQ 311
+ I+ + +A+ + +LD N +L + L PI +F+K S + L + R + Q
Sbjct: 399 TSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQ 457
Query: 312 MKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
+ + M KL Q E F I+ + LE+ + + +E
Sbjct: 458 ANKIYDKAM---KLEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 45.1 bits (105), Expect = 1e-04
Identities = 76/339 (22%), Positives = 127/339 (37%), Gaps = 61/339 (17%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVK---EGGDIAFIPS 120
VR Y D P QG +NF+ D LH+ ++WW R V E ++ IPS
Sbjct: 586 VRALFDYDKTKDSGLPSQG--LNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPS 643
Query: 121 PQRLES---IRLKQ---EQKARRSG---NPSSLSDIGNRRSPPPSLAKQKQK-------- 163
+R+E RLK K R G N ++ +R+ P Q ++
Sbjct: 644 KRRVEKKERARLKTVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQH 703
Query: 164 --------------QAEHVPPYDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFL 204
Q E+V Y+ V RPV+++GP + D + L
Sbjct: 704 VTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEF 757
Query: 205 KHRFDGRI-SITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEV--------QSEIE 255
+F + TR D + R + R +E+ E + ++
Sbjct: 758 PDKFGSCVPHTTRPKRDYEVDGRD-YHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQ 816
Query: 256 RIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHL 315
+ E+A+ + +LD N +L L PI +F+K S + + + + + Q +
Sbjct: 817 SVREVAEKGKHCILDVSG-NAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKT 875
Query: 316 TVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
+ M KL Q E F I+ + LED + + +E
Sbjct: 876 FERAM---KLEQEFTEHFTAIVQGDTLEDIYNQVKQIIE 911
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 42.4 bits (98), Expect = 0.001
Identities = 74/308 (24%), Positives = 117/308 (37%), Gaps = 48/308 (15%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGD---IAFIPS 120
VR Y D P QG ++F+ D LH+ ++WW R V GD + IPS
Sbjct: 438 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 495
Query: 121 PQRL---ESIRLKQEQKARRSGNPSSLSDI---GNRRSPPPSLAKQKQKQAEHVP-PYDV 173
+R+ E RLK + + G S DI G+ +L Q+ + P
Sbjct: 496 KRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPVTRQE 555
Query: 174 VPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADLSLAKRSVLNNP 232
+ RPV+++GP + D + L +F + TR D + R
Sbjct: 556 INYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDY---- 605
Query: 233 GKRTIIERSSARSSIAEVQ-------------SEIERIFELAKSLQLVVLDADTINHPAQ 279
+I R I E + + ++ + +A+ + +LD N +
Sbjct: 606 --HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSG-NAIKR 662
Query: 280 LAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYD---KLVQCPPESFDVI 336
L L PI +F+K S + L + + + Q K YD KL Q E F I
Sbjct: 663 LQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAK------KTYDRAIKLEQEFGEYFTAI 716
Query: 337 LDENQLED 344
+ + LED
Sbjct: 717 VQGDTLED 724
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 42.4 bits (98), Expect = 0.001
Identities = 74/308 (24%), Positives = 117/308 (37%), Gaps = 48/308 (15%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGD---IAFIPS 120
VR Y D P QG ++F+ D LH+ ++WW R V GD + IPS
Sbjct: 23 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 80
Query: 121 PQRL---ESIRLKQEQKARRSGNPSSLSDI---GNRRSPPPSLAKQKQKQAEHVP-PYDV 173
+R+ E RLK + + G S DI G+ +L Q+ + P
Sbjct: 81 KRRVERKERARLKTVKFNAKPGVIDSKGDIPGLGDDGYGTKTLRGQEDLILSYEPVTRQE 140
Query: 174 VPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTADLSLAKRSVLNNP 232
+ RPV+++GP + D + L +F + TR D + R
Sbjct: 141 INYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDY---- 190
Query: 233 GKRTIIERSSARSSIAEVQ-------------SEIERIFELAKSLQLVVLDADTINHPAQ 279
+I R I E + + ++ + +A+ + +LD N +
Sbjct: 191 --HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILDVSG-NAIKR 247
Query: 280 LAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYD---KLVQCPPESFDVI 336
L L PI +F+K S + L + + + Q K YD KL Q E F I
Sbjct: 248 LQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAK------KTYDRAIKLEQEFGEYFTAI 301
Query: 337 LDENQLED 344
+ + LED
Sbjct: 302 VQGDTLED 309
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV-KEGGDIAFIPSPQ 122
VR Y D+ P + +G+ F D + I K ++WW G+L + G IPSP+
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPE 647
Query: 123 RLE-------SIRLKQEQKA 135
E + KQEQ+A
Sbjct: 648 LQEWRVACIAMEKTKQEQQA 667
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV-KEGGDIAFIPSPQ 122
VR Y D+ P + +G+ F D + I K ++WW G+L + G IPSP+
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPE 653
Query: 123 RLE-------SIRLKQEQKA 135
E + KQEQ+A
Sbjct: 654 LQEWRVACIAMEKTKQEQQA 673
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV-KEGGDIAFIPSPQ 122
VR Y D+ P + +G+ F D + I K ++WW G+L + G IPSP+
Sbjct: 617 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPE 676
Query: 123 RLE-------SIRLKQEQKA 135
E + KQEQ+A
Sbjct: 677 LQEWRVACIAMEKTKQEQQA 696
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 40.4 bits (93), Expect = 0.004
Identities = 75/326 (23%), Positives = 119/326 (36%), Gaps = 66/326 (20%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGD---IAFIPS 120
VR Y D P QG ++F+ D LH+ ++WW R V GD + IPS
Sbjct: 646 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 703
Query: 121 PQRL---ESIRLKQEQKARRSGNPSSLSDIGNRRSPP-------PSLAKQKQKQAEHVPP 170
+R+ E RLK + + G S ++R P ++Q + E P
Sbjct: 704 KRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDP 763
Query: 171 ----------YDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SI 214
Y+ V RPV+++GP + D + L +F +
Sbjct: 764 ERGQEDLILSYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHT 817
Query: 215 TRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQ-------------SEIERIFELA 261
TR D + R +I R I E + + ++ + +A
Sbjct: 818 TRPKRDYEVDGRDY------HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVA 871
Query: 262 KSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMA 321
+ + +LD N +L L PI +F+K S + L + + + Q K
Sbjct: 872 ERGKHCILDVSG-NAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAK------KT 924
Query: 322 YD---KLVQCPPESFDVILDENQLED 344
YD KL Q E F I+ + LED
Sbjct: 925 YDRAIKLEQEFGEYFTAIVQGDTLED 950
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 40.4 bits (93), Expect = 0.004
Identities = 75/326 (23%), Positives = 119/326 (36%), Gaps = 66/326 (20%)
Query: 64 VRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGD---IAFIPS 120
VR Y D P QG ++F+ D LH+ ++WW R V GD + IPS
Sbjct: 541 VRAMFDYDKSKDSGLPSQG--LSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 598
Query: 121 PQRL---ESIRLKQEQKARRSGNPSSLSDIGNRRSPP-------PSLAKQKQKQAEHVPP 170
+R+ E RLK + + G S ++R P ++Q + E P
Sbjct: 599 KRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDP 658
Query: 171 ----------YDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-SI 214
Y+ V RPV+++GP + D + L +F +
Sbjct: 659 ERGQEDLILSYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHT 712
Query: 215 TRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQ-------------SEIERIFELA 261
TR D + R +I R I E + + ++ + +A
Sbjct: 713 TRPKRDYEVDGRDY------HFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVA 766
Query: 262 KSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMA 321
+ + +LD N +L L PI +F+K S + L + + + Q K
Sbjct: 767 ERGKHCILDVSG-NAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAK------KT 819
Query: 322 YD---KLVQCPPESFDVILDENQLED 344
YD KL Q E F I+ + LED
Sbjct: 820 YDRAIKLEQEFGEYFTAIVQGDTLED 845
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 40.0 bits (92), Expect = 0.005
Identities = 65/328 (19%), Positives = 133/328 (40%), Gaps = 36/328 (10%)
Query: 50 QQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV 109
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW +
Sbjct: 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAY 393
Query: 110 KEGGD-----IAFIPS---PQRLESIR--LKQEQKARRSGNP-SSLSDIGNRRSPPPSLA 158
+EG + +P Q+ E+++ ++++++ +SG + + R+ +
Sbjct: 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
Query: 159 KQKQKQAEHVPPYDVVP-------SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
K E + Y+ + RP++L+GP G + +++ L + K RF
Sbjct: 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
Query: 212 I-SITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAE--------VQSEIERIFELAK 262
+ TR D +A R + R E A E + I+ + ++
Sbjct: 511 VPHTTRSRRDQEVAGRDY--HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVIN 568
Query: 263 SLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKS-QMKHLTVQMMA 321
S ++ +L T L + L P I+F+ S + L+ L+ GK+ + + L +
Sbjct: 569 SGKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 627
Query: 322 YDKLVQCPPESFDVILDENQLEDACEHL 349
++ Q FD + + L+ A + L
Sbjct: 628 TREMEQNNGHYFDTAIVNSDLDKAYQEL 655
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,147,793
Number of Sequences: 37866
Number of extensions: 998345
Number of successful extensions: 3436
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 3304
Number of HSP's gapped (non-prelim): 138
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.