Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40254823
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
(1188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 2419 0.0
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 2414 0.0
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 831 0.0
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 177 4e-44
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 177 4e-44
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 174 6e-43
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 170 8e-42
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 162 2e-39
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 162 2e-39
gi|26190608 synaptojanin 2 [Homo sapiens] 155 2e-37
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 152 1e-36
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 138 3e-32
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 120 1e-26
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 110 8e-24
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 94 1e-18
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 94 1e-18
gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens] 92 2e-18
gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens] 92 2e-18
gi|54792745 SH2 domain containing 1B [Homo sapiens] 84 8e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni... 77 7e-14
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 67 1e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 67 1e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 67 1e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 67 1e-10
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 64 1e-09
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 63 2e-09
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 62 4e-09
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 62 4e-09
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 60 2e-08
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 60 2e-08
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 2419 bits (6268), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED 60
MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED
Sbjct: 1 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED 60
Query: 61 DKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESVV 120
DKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESVV
Sbjct: 61 DKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESVV 120
Query: 121 SPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHL 180
SPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHL
Sbjct: 121 SPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHL 180
Query: 181 KAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQ 240
KAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQ
Sbjct: 181 KAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQ 240
Query: 241 LSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTF 300
LSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTF
Sbjct: 241 LSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVTF 300
Query: 301 EVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILV 360
EVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILV
Sbjct: 301 EVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILV 360
Query: 361 ETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKK 420
ETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKK
Sbjct: 361 ETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKK 420
Query: 421 ITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVA 480
ITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVA
Sbjct: 421 ITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVA 480
Query: 481 IHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSH 540
IHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSH
Sbjct: 481 IHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSH 540
Query: 541 LTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAET 600
LTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAET
Sbjct: 541 LTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAET 600
Query: 601 IIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKA 660
IIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKA
Sbjct: 601 IIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKA 660
Query: 661 TGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNG 720
TGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNG
Sbjct: 661 TGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNG 720
Query: 721 PGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFG 780
PGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFG
Sbjct: 721 PGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFG 780
Query: 781 ETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHG 840
ETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHG
Sbjct: 781 ETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHG 840
Query: 841 ELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPP 900
ELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPP
Sbjct: 841 ELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPP 900
Query: 901 CSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESP 960
CSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESP
Sbjct: 901 CSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESP 960
Query: 961 PTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPL 1020
PTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPL
Sbjct: 961 PTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPL 1020
Query: 1021 YGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAP 1080
YGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAP
Sbjct: 1021 YGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAP 1080
Query: 1081 RLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRP 1140
RLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRP
Sbjct: 1081 RLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRP 1140
Query: 1141 PLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ 1188
PLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ
Sbjct: 1141 PLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ 1188
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 2414 bits (6256), Expect = 0.0
Identities = 1188/1189 (99%), Positives = 1188/1189 (99%), Gaps = 1/1189 (0%)
Query: 1 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED 60
MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED
Sbjct: 1 MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNED 60
Query: 61 DKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDT-ESV 119
DKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDT ESV
Sbjct: 61 DKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTVESV 120
Query: 120 VSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEH 179
VSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEH
Sbjct: 121 VSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEH 180
Query: 180 LKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQ 239
LKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQ
Sbjct: 181 LKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQ 240
Query: 240 QLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVT 299
QLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVT
Sbjct: 241 QLSPGLRPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHEGPESPHRPSLIPPVT 300
Query: 300 FEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVIL 359
FEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVIL
Sbjct: 301 FEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVIL 360
Query: 360 VETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPK 419
VETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPK
Sbjct: 361 VETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPK 420
Query: 420 KITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTV 479
KITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTV
Sbjct: 421 KITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTV 480
Query: 480 AIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNS 539
AIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNS
Sbjct: 481 AIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNS 540
Query: 540 HLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAE 599
HLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAE
Sbjct: 541 HLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAE 600
Query: 600 TIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQK 659
TIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQK
Sbjct: 601 TIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQK 660
Query: 660 ATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN 719
ATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN
Sbjct: 661 ATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKN 720
Query: 720 GPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKF 779
GPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKF
Sbjct: 721 GPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKF 780
Query: 780 GETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHH 839
GETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHH
Sbjct: 781 GETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALRLEATETQLPIYTPLTHH 840
Query: 840 GELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAP 899
GELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAP
Sbjct: 841 GELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAP 900
Query: 900 PCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGES 959
PCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGES
Sbjct: 901 PCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGES 960
Query: 960 PPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENP 1019
PPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENP
Sbjct: 961 PPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENP 1020
Query: 1020 LYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPA 1079
LYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPA
Sbjct: 1021 LYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPA 1080
Query: 1080 PRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR 1139
PRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR
Sbjct: 1081 PRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR 1140
Query: 1140 PPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ 1188
PPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ
Sbjct: 1141 PPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ 1189
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
Length = 1258
Score = 831 bits (2146), Expect = 0.0
Identities = 488/1128 (43%), Positives = 665/1128 (58%), Gaps = 91/1128 (8%)
Query: 3 PCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDK 62
P W H +++R+ AEELL+R G+DGSFLVR SES++ A+ALCVLY+ V+TYRILP+ +D
Sbjct: 19 PSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDF 78
Query: 63 FTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTESVVSP 122
VQ S+GV +R F L +LI Y + N GLV L PV E E D + ++
Sbjct: 79 LAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDGEDEK 138
Query: 123 PELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKA 182
P LPPR+ + S+ P A ET +E+ L ++
Sbjct: 139 PPLPPRSGSTSISAPTGPSSPLP-----APETPTAPAAESAPNGLSTVS----------- 182
Query: 183 IQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQLS 242
DYL D E V+ G+S LPHL + C+ L+ EV + L LE L ++FDQQ S
Sbjct: 183 -HDYLKGSYGLDLEAVRGGASHLPHLTRTLATSCRRLHSEVDKVLSGLEILSKVFDQQSS 241
Query: 243 P---GLRPRPQVP--GEANPINMVSKLSQLTSLLSSIEDK-VKALLHEGPESPHRPS--- 293
P L + +P GE ++V KLS L LS I+ K +KAL +P P
Sbjct: 242 PMVTRLLQQQNLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPQPST 301
Query: 294 ----LIPPVTFEVKAE-------SLGIPQKMQLKVDVESGKLII-KKSKDGSED-KFYSH 340
IP FEVK + +G QK L VDVE G+L++ ++ +D ED ++H
Sbjct: 302 RKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTH 361
Query: 341 KKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEP 400
+I QLIKSQ+ NKL ++ E EK++ RK+++F ++KRE FCQLLQ MKNKHS+Q EP
Sbjct: 362 DRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEP 421
Query: 401 DMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEW 460
DMI++FIGTWNMG+ PPPK +TSWF SKG GKT D+ IPHDIYV GTQE+ + ++EW
Sbjct: 422 DMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQENSVGDREW 481
Query: 461 LEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNK 520
L++L+ L+E+T + ++ +A+ +LWNI++ VL KPEHENRISH+ T +VKTGIANTLGNK
Sbjct: 482 LDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNK 541
Query: 521 GAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTH 580
GAVGVSFMFNGTS GFVN HLTSG+EK RRNQNY++ILR L+LGD++L+ F+I+ RFTH
Sbjct: 542 GAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQLNAFDISLRFTH 601
Query: 581 LFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFA 640
LFWFGDLNYR+D+ + + I+ I ++++ LL DQL ER + KVFL F EEEI+F
Sbjct: 602 LFWFGDLNYRLDM---DIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFP 658
Query: 641 PTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDH 700
PTYR+ER +RD YA+ KQK TG++ N+PSWCDR+LWKSYP H++C SYG T DI+TSDH
Sbjct: 659 PTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDH 718
Query: 701 SPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFV 760
SPVF TFE GVTSQF+SK G Q IEF A +KT S+TKF++EF+S+CLE +
Sbjct: 719 SPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYK 778
Query: 761 KSQEGENEEGSE-GELVVKF-GETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGC 818
KS E + + L V++ LP LKPI++D EYL DQH+L+++KS D ESYGE
Sbjct: 779 KSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECV 838
Query: 819 IALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQ--TSQGKTREKLYDFVKTERDESSG 876
+AL+ T T L+H GE TG+ +G +K++ T + TRE+LY+++ ++DE+
Sbjct: 839 VALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDEAGA 898
Query: 877 PKTLKSLT--SHDPMKQWEVTSRAPPCSGSS------ITEIINPNYMGVGPFGPPMPLHV 928
S++ S +P SR P + +S E P G P PP
Sbjct: 899 KSKAPSVSRGSQEPRS----GSRKPAFTEASCPLSRLFEEPEKPPPTGRPP-APPRAAPR 953
Query: 929 KQTLSPDQQPTAWSYDQ-----PPKDSPLGPC----RGESPPTPPGQPPISPKKFLPSTA 979
++ L+P +P + PPK+S P G P +PP + +PS
Sbjct: 954 EEPLTPRLKPEGAPEPEGVAAPPPKNSFNNPAYYVLEGVPHQLLPPEPPSPARAPVPSAT 1013
Query: 980 NRGLP-------------PRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLY--GSL 1024
+ PR E SD + +G TLP D P P + ++ ++ SL
Sbjct: 1014 KNKVAITVPAPQLGHHRHPRVGEGSSSD--EESGGTLPPPDFP--PPPLPDSAIFLPPSL 1069
Query: 1025 SSFPKPAPR----KDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEAD 1068
P P R + P P+ P P PG S L + D
Sbjct: 1070 DPLPGPVVRGRGGAEARGPPPPKAHPRPPLPPGPSPASTFLGEVASGD 1117
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 177 bits (450), Expect = 4e-44
Identities = 205/830 (24%), Positives = 331/830 (39%), Gaps = 141/830 (16%)
Query: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 554 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 613
Query: 436 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 614 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 671
Query: 484 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 672 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 731
Query: 544 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 732 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 783
Query: 604 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 784 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 836
Query: 664 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 837 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 896
Query: 699 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754
DH PV A + + + + QG + + + + F+ +
Sbjct: 897 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 956
Query: 755 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 957 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 1016
Query: 815 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871
E + LE LP T T G E+ F E + + E L + +
Sbjct: 1017 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1071
Query: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
SSG T S + R PC +I+E GP L ++ +
Sbjct: 1072 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1108
Query: 932 LSPDQQPTAWSYDQPPKDS-PLGPCRGESP--PTPPGQPPISPKKFLPSTANRGLPPRTQ 988
+P + P S P D+ P P + P P P +PP P+ P T R PP Q
Sbjct: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP-PPRPVAPPT--RPAPP--Q 1163
Query: 989 ESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKP-APRKDQESPKMP---RK 1044
P ++ T + +G + + P P R++ E+PK P RK
Sbjct: 1164 RPPPPSGARSPAPTRKE---------------FGGIGAPPSPGVARREMEAPKSPGTTRK 1208
Query: 1045 E----PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1100
+ P P+ G+ P G + PR + S +AG
Sbjct: 1209 DNIGRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
Query: 1101 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1147
+ + KT +S+ P+KP + Q + P P R P +PV +P
Sbjct: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/219 (23%), Positives = 76/219 (34%), Gaps = 36/219 (16%)
Query: 945 QPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLP 1004
QP S LG SP T P Q P + +PS LP R + G + + P
Sbjct: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS-----LPIRPSRAPSRTPGPPSAQSSP 1124
Query: 1005 QEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKA 1064
+ P T P P+KD P P++ PPP P + P T+
Sbjct: 1125 IDAQPAT------------------PLPQKDPAQPLEPKRPPPPRP---VAPP----TRP 1159
Query: 1065 QEADRGEGP-GKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKP 1123
R P G + PAP + F A + PK+P +++ + P
Sbjct: 1160 APPQRPPPPSGARSPAPTRKEFG-GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSP 1218
Query: 1124 SRSEINQQTPPTPTPRPPLPVKSPAV----LHLQHSKGR 1158
T RP +P ++ + H + S GR
Sbjct: 1219 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1257
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 177 bits (450), Expect = 4e-44
Identities = 205/830 (24%), Positives = 331/830 (39%), Gaps = 141/830 (16%)
Query: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 554 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 613
Query: 436 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 614 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 671
Query: 484 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 672 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 731
Query: 544 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 732 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 783
Query: 604 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 784 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 836
Query: 664 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 837 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 896
Query: 699 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754
DH PV A + + + + QG + + + + F+ +
Sbjct: 897 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 956
Query: 755 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 957 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 1016
Query: 815 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871
E + LE LP T T G E+ F E + + E L + +
Sbjct: 1017 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1071
Query: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
SSG T S + R PC +I+E GP L ++ +
Sbjct: 1072 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1108
Query: 932 LSPDQQPTAWSYDQPPKDS-PLGPCRGESP--PTPPGQPPISPKKFLPSTANRGLPPRTQ 988
+P + P S P D+ P P + P P P +PP P+ P T R PP Q
Sbjct: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP-PPRPVAPPT--RPAPP--Q 1163
Query: 989 ESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKP-APRKDQESPKMP---RK 1044
P ++ T + +G + + P P R++ E+PK P RK
Sbjct: 1164 RPPPPSGARSPAPTRKE---------------FGGIGAPPSPGVARREMEAPKSPGTTRK 1208
Query: 1045 E----PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1100
+ P P+ G+ P G + PR + S +AG
Sbjct: 1209 DNIGRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
Query: 1101 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1147
+ + KT +S+ P+KP + Q + P P R P +PV +P
Sbjct: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/219 (23%), Positives = 76/219 (34%), Gaps = 36/219 (16%)
Query: 945 QPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLP 1004
QP S LG SP T P Q P + +PS LP R + G + + P
Sbjct: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS-----LPIRPSRAPSRTPGPPSAQSSP 1124
Query: 1005 QEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKA 1064
+ P T P P+KD P P++ PPP P + P T+
Sbjct: 1125 IDAQPAT------------------PLPQKDPAQPLEPKRPPPPRP---VAPP----TRP 1159
Query: 1065 QEADRGEGP-GKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKP 1123
R P G + PAP + F A + PK+P +++ + P
Sbjct: 1160 APPQRPPPPSGARSPAPTRKEFG-GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSP 1218
Query: 1124 SRSEINQQTPPTPTPRPPLPVKSPAV----LHLQHSKGR 1158
T RP +P ++ + H + S GR
Sbjct: 1219 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1257
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 174 bits (440), Expect = 6e-43
Identities = 208/852 (24%), Positives = 337/852 (39%), Gaps = 136/852 (15%)
Query: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 510 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 569
Query: 436 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 570 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 627
Query: 484 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 628 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 687
Query: 544 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 688 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 739
Query: 604 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 740 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 792
Query: 664 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 793 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 852
Query: 699 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754
DH PV A + + + + QG + + + + F+ +
Sbjct: 853 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 912
Query: 755 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 913 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 972
Query: 815 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871
E + LE LP T T G E+ F E + + E L + +
Sbjct: 973 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1027
Query: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
SSG T S + R PC +I+E GP L ++ +
Sbjct: 1028 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1064
Query: 932 LSPDQQPTAWSYDQPPKDS----------PLGPCRGESPPTP-PGQPPI--SPKKFLPST 978
+P + P S P D+ P P + PP P P PP +P + P
Sbjct: 1065 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1124
Query: 979 ANRGLP-PRTQESRPSDLG-KNAGDTLPQEDLPLTKPEMFENPLYGSLS----------- 1025
+ R P P+ + P G A T+P ++ P+ G L+
Sbjct: 1125 SGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETS 1184
Query: 1026 --SFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV---PAP 1080
S P P K Q + PPP L +V A G P + P P
Sbjct: 1185 KGSTFLPEPLKPQAAFPPQSSLPPPAQR---LQEPLVPVAAPMPQSGPQPNLETPPQPPP 1241
Query: 1081 RLR---SFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAK-RPIKPSRSEINQQTPPTP 1136
R R S +S++ + S GK ++P+ + S+++++ QT P P
Sbjct: 1242 RSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVP 1301
Query: 1137 TPRPPLPVKSPA 1148
TP P ++ P+
Sbjct: 1302 TPDPKRLIQLPS 1313
Score = 36.6 bits (83), Expect = 0.15
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 1088 SSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRP------- 1140
SSS G + ++P S+ PVP+ PI+PSR+ PP+ P
Sbjct: 1029 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSL-PIRPSRAPSRTPGPPSAQSSPIDAQPAT 1087
Query: 1141 PLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRT 1185
PLP K PA Q + + + + P + PP P GR+
Sbjct: 1088 PLPQKDPA----QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRS 1128
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 170 bits (430), Expect = 8e-42
Identities = 204/827 (24%), Positives = 326/827 (39%), Gaps = 151/827 (18%)
Query: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 515 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 574
Query: 436 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 575 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 632
Query: 484 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 633 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 692
Query: 544 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 693 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 744
Query: 604 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 745 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 797
Query: 664 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 798 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 857
Query: 699 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754
DH PV A + + + + QG + + + + F+ +
Sbjct: 858 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 917
Query: 755 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 918 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 977
Query: 815 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871
E + LE LP T T G E+ F E + + E L + +
Sbjct: 978 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1032
Query: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
SSG T S + R PC +I+E GP L ++ +
Sbjct: 1033 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1069
Query: 932 LSPDQQPTAWSYDQPPKDS-PLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQES 990
+P + P S P D+ P P P P Q P+ PK+ PP
Sbjct: 1070 RAPSRTPGPPSAQSSPIDAQPATPL----PQKDPAQ-PLEPKR----------PPP---- 1110
Query: 991 RPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMP---RKE-- 1045
P+ P T+P + P S + P P RK+ +PK P RK+
Sbjct: 1111 -------------PRPVAPPTRPAPPQRPPPPSGARSPAPT-RKEFGAPKSPGTTRKDNI 1156
Query: 1046 --PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQG 1103
P P+ G+ P G + PR + S +AG +
Sbjct: 1157 GRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPES 1207
Query: 1104 KPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1147
+ KT +S+ P+KP + Q + P P R P +PV +P
Sbjct: 1208 QSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1254
Score = 31.6 bits (70), Expect = 4.7
Identities = 34/143 (23%), Positives = 48/143 (33%), Gaps = 25/143 (17%)
Query: 1048 PCPEPGILS---PSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGK 1104
PC P I PS+ + ++ R GP + SS Q
Sbjct: 1050 PCQSPTISEGPVPSLPIRPSRAPSRTPGPP-----------SAQSSPIDAQPATPLPQKD 1098
Query: 1105 PKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNT 1164
P P+ + P P + P+R Q+ PP R P P + S G +DN
Sbjct: 1099 PAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKE--FGAPKSPGTTRKDNI 1156
Query: 1165 ELPHHGKHRPEE----GPPGPLG 1183
G+ +P PGP G
Sbjct: 1157 -----GRSQPSPQAGLAGPGPAG 1174
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 162 bits (410), Expect = 2e-39
Identities = 114/358 (31%), Positives = 175/358 (48%), Gaps = 42/358 (11%)
Query: 368 LRKEYV-FADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFL 426
+RK +V S +REG + + + K E F+GTWN+ P + W
Sbjct: 206 MRKLFVPNTQSGQREGLIKHILAKREK--EYVNIQTFRFFVGTWNVNGQSPDSGLEPWL- 262
Query: 427 SKGQGKTRDDSADYIPHDIYVIGTQEDPLS-----------EKEWLEILKHSLQEITSVT 475
+ D P DIY IG QE LS E+EW ++ L +
Sbjct: 263 ----------NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLH--SKAK 310
Query: 476 FKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLG 535
+K V + L + +++ A+ + I I T+ V TGI +GNKG V V F+F+ T+
Sbjct: 311 YKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFC 370
Query: 536 FVNSHLTSGSEKKLRRNQNYMNILRFLA--LGDKKLSPFNITHRFTHLFWFGDLNYRVDL 593
VNSHL + E RRNQ+Y +I ++ + ++ L NI + + W GDLNYR+ +
Sbjct: 371 IVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIM-KHEVVIWLGDLNYRLCM 429
Query: 594 PTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKY 653
P +A + I ++ LL DQL +R ++K F+ F E EI F PTY+++
Sbjct: 430 P--DANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD------- 480
Query: 654 AYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 711
+ T + + K +P+WCDR+LW+ +V +Y S ++ TSDH PV A F GV
Sbjct: 481 SKTDRWDSSGKCRVPAWCDRILWRG---TNVNQLNYRSHMELKTSDHKPVSALFHIGV 535
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 162 bits (410), Expect = 2e-39
Identities = 114/358 (31%), Positives = 175/358 (48%), Gaps = 42/358 (11%)
Query: 368 LRKEYV-FADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFL 426
+RK +V S +REG + + + K E F+GTWN+ P + W
Sbjct: 206 MRKLFVPNTQSGQREGLIKHILAKREK--EYVNIQTFRFFVGTWNVNGQSPDSGLEPWL- 262
Query: 427 SKGQGKTRDDSADYIPHDIYVIGTQEDPLS-----------EKEWLEILKHSLQEITSVT 475
+ D P DIY IG QE LS E+EW ++ L +
Sbjct: 263 ----------NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLH--SKAK 310
Query: 476 FKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLG 535
+K V + L + +++ A+ + I I T+ V TGI +GNKG V V F+F+ T+
Sbjct: 311 YKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFC 370
Query: 536 FVNSHLTSGSEKKLRRNQNYMNILRFLA--LGDKKLSPFNITHRFTHLFWFGDLNYRVDL 593
VNSHL + E RRNQ+Y +I ++ + ++ L NI + + W GDLNYR+ +
Sbjct: 371 IVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIM-KHEVVIWLGDLNYRLCM 429
Query: 594 PTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKY 653
P +A + I ++ LL DQL +R ++K F+ F E EI F PTY+++
Sbjct: 430 P--DANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD------- 480
Query: 654 AYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 711
+ T + + K +P+WCDR+LW+ +V +Y S ++ TSDH PV A F GV
Sbjct: 481 SKTDRWDSSGKCRVPAWCDRILWRG---TNVNQLNYRSHMELKTSDHKPVSALFHIGV 535
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 155 bits (393), Expect = 2e-37
Identities = 230/956 (24%), Positives = 360/956 (37%), Gaps = 182/956 (19%)
Query: 322 GKLIIKKSKDGSEDKFYS-HKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKR 380
GK + K KDG+ + +K + KL+++ + E++ K + DS
Sbjct: 450 GKAKVGKLKDGARSMSRTIQSNFFDGVKQEAI--KLLLVGDVYGEEVADKGGMLLDSTAL 507
Query: 381 EGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMG-------NAPPPKKITSWFLSKGQGKT 433
++L+ M + SE I I +GTWN+ N ++T W L Q
Sbjct: 508 LVTPRILKAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSG 567
Query: 434 RDDSAD-YIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVA 480
DS D P DI+ +G +E ++K W E L+ ++ T A
Sbjct: 568 ATDSQDDSSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSA 627
Query: 481 IHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSH 540
L + + + +P H I + D VKTG+ GNKGAVG+ F F+ TS F+ SH
Sbjct: 628 --QLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSH 685
Query: 541 LTSGSEKKLRRNQNYMNILRFLA--LGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEA 598
LT+G + RN++Y I + L +G S ++FW GD NYR+DL
Sbjct: 686 LTAGQSQVKERNEDYKEITQKLCFPMGRNVFS-------HDYVFWCGDFNYRIDL---TY 735
Query: 599 ETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQ 658
E + +K+Q + LL DQL ++ K+F F E I F PTY+++ AY
Sbjct: 736 EEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYD---VGSAAYD-- 790
Query: 659 KATGMKYNLPSWCDRVLW--KSYPLVHVVCQ-----------------------SYGSTS 693
T K P+W DRVLW K +P + Y +
Sbjct: 791 --TSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRA 848
Query: 694 DIMTSDHSPVFATFEAGVTSQFVS---------KNGPGTVDSQGQIEFLRCYATLKTKSQ 744
++ SDH PV A E V V + G +D+ + TL+ K++
Sbjct: 849 ELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQS--PTLEEKNE 906
Query: 745 TKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILIS 804
F + + +++ ++G+++V F ++ L + D + + + I
Sbjct: 907 --FPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKGRAVKIR 964
Query: 805 IKSSDSDESYGEGCIALRLEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLY 864
K+ D + E I R ++ P+ +P + L +F S+G E
Sbjct: 965 PKTKDWLKGLREEIIRKR----DSMAPV-SPTANSCLLEENFDFTSLDYESEGDILEDDE 1019
Query: 865 DFVKTERDESSGPKTLKSLTSHDPMKQWE-VTSRAPPCSGSSIT-EIINPNYM------- 915
D++ DE + P S D + T+ APP ++T + +P Y
Sbjct: 1020 DYLV---DEFNQPGVSDSELGGDDLSDVPGPTALAPPSKSPALTKKKQHPTYKDDADLVE 1076
Query: 916 ------GVGPF---GPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPT---- 962
VG F P L V P Q P +PP + L + S +
Sbjct: 1077 LKRELEAVGEFRHRSPSRSLSVPNRPRPPQPP-----QRPPPPTGLMVKKSASDASISSG 1131
Query: 963 PPGQPPI-SPKKFLPSTANRGLPPRTQESRPSDLGK-----------------NAGDTLP 1004
GQ I + LP + RT S+P ++ + A
Sbjct: 1132 THGQYSILQTARLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLLEARGGAS 1191
Query: 1005 QEDLPLTKPEMFENPLYGSLSSFPKPA-----PRKDQESPKMPRKEPPPCP---EPGI-- 1054
+E L P E SS P+P P Q P +PR+ PP P +P +
Sbjct: 1192 EEALSAVAPRDLE------ASSEPEPTPGAAKPETPQAPPLLPRRPPPRVPAIKKPTLRR 1245
Query: 1055 ----LSP-------SIVLTKAQEADRGEGP-----GKQVPAPRLRSFTCSSSAEGRAAGG 1098
LSP ++ T E P + P P+ R+F +AE
Sbjct: 1246 TGKPLSPEEQFEQQTVHFTIGPPETSVEAPPVVTAPRVPPVPKPRTFQPGKAAE------ 1299
Query: 1099 DKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKS-PAVLHLQ 1153
+ + P S +AP A + P + PP PP KS PA HLQ
Sbjct: 1300 ---RPSHRKPASDEAPPGAGASVPPP-----LEAPPLVPKVPPRRKKSAPAAFHLQ 1347
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 152 bits (385), Expect = 1e-36
Identities = 106/336 (31%), Positives = 160/336 (47%), Gaps = 44/336 (13%)
Query: 394 HSEQPEPDMITI-----FIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVI 448
H Q E D I F GT+N+ P + + W + Q D+Y +
Sbjct: 251 HLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAP-----------DVYCV 299
Query: 449 GTQEDPLS-----------EKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEH 497
G QE LS E+EW + + L + V + L I +++ K EH
Sbjct: 300 GFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHP--DAKYAKVKLIRLVGIMLLLYVKQEH 357
Query: 498 ENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMN 557
IS + + V TGI +GNKG V + F F+ TS+ VNSHL + E+ RRNQ+Y +
Sbjct: 358 AAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKD 417
Query: 558 ILRFLAL--GDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLS 615
I + D L P I++ + W GDLNYR++ + E + + I+++ + L +
Sbjct: 418 ICSRMQFCQPDPSLPPLTISNHDV-ILWLGDLNYRIE--ELDVEKVKKLIEEKDFQMLYA 474
Query: 616 HDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL 675
+DQL + + VF F E E+TF PTY+++ + D T K P+WCDR+L
Sbjct: 475 YDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDD-------WDTSEKCRAPAWCDRIL 527
Query: 676 WKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 711
WK + + SY S + TSDH PV + F+ GV
Sbjct: 528 WKGKNITQL---SYQSHMALKTSDHKPVSSVFDIGV 560
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 138 bits (348), Expect = 3e-32
Identities = 102/320 (31%), Positives = 151/320 (47%), Gaps = 34/320 (10%)
Query: 403 ITIFIGTWNM-GNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWL 461
+ +F+ TWNM G P + + L ADY D+YVIG QE +EW
Sbjct: 299 VALFVATWNMQGQKELPPSLDEFLLPA--------EADYA-QDLYVIGVQEGCSDRREWE 349
Query: 462 EILKHSLQE---ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLG 518
L+ +L + S V +L+ R ++ E E V T I + +
Sbjct: 350 TRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVE-------CSTVTTRIVSQIK 402
Query: 519 NKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLAL-------GDKKLSP 571
KGA+G+SF F GTS F+ SH TSG K R +Y ++ L L + S
Sbjct: 403 TKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSA 462
Query: 572 FNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLH 631
++T RF +FWFGD N+R+ + ++ + LL HDQL+ E R+ +F
Sbjct: 463 ADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKG 522
Query: 632 FEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGS 691
F+E +I F P+Y+F+ + +D Y T ++ T PS+ DRVL++S + SY S
Sbjct: 523 FQEPDIHFLPSYKFD-IGKDTYDSTSKQRT------PSYTDRVLYRSRHKGDICPVSYSS 575
Query: 692 TSDIMTSDHSPVFATFEAGV 711
I TSDH PV+ F V
Sbjct: 576 CPGIKTSDHRPVYGLFRVKV 595
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
A [Homo sapiens]
Length = 638
Score = 120 bits (300), Expect = 1e-26
Identities = 97/345 (28%), Positives = 147/345 (42%), Gaps = 51/345 (14%)
Query: 389 QMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVI 448
Q+ K + P I + TWN+G A PP +TS L G G D + D+ I
Sbjct: 41 QLPAKKNAALGPSEPRITVVTWNVGTAMPPDDVTS-LLHLGGGDDSDGA------DMIAI 93
Query: 449 GTQE----------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHE 498
G QE D L +W E+ +L V +V + + +++ AK H
Sbjct: 94 GLQEVNSMLNKRLKDALFTDQWSELFMDALGPFNFVLVSSVRMQ---GVILLLFAKYYHL 150
Query: 499 NRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNI 558
+ + TD +TG+ GNKG V V G L F+N HL + +K +R N+ I
Sbjct: 151 PFLRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTI 210
Query: 559 L---RFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLS 615
L +F G + + ++ +FWFGDLN+R++ +++ + I Q L
Sbjct: 211 LSLQQFQGPGAQGILDHDL------VFWFGDLNFRIE--SYDLHFVKFAIDSDQLHQLWE 262
Query: 616 HDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL 675
DQL + + F+E + FAPT++F+ T + T K P+W DR+L
Sbjct: 263 KDQLNMAKNTWPILKGFQEGPLNFAPTFKFD-------VGTNKYDTSAKKRKPAWTDRIL 315
Query: 676 WK-------------SYPLVHVVCQSYGSTSDIMTSDHSPVFATF 707
WK + V SY S + SDH PV A F
Sbjct: 316 WKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQF 360
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 110 bits (275), Expect = 8e-24
Identities = 86/343 (25%), Positives = 144/343 (41%), Gaps = 48/343 (13%)
Query: 390 MKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIG 449
M ++ P+ ++I + TWN+ +A PP ++ + + DIYVIG
Sbjct: 1 MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRN---------LNLDIYVIG 51
Query: 450 TQE----------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHEN 499
QE D W L + ++ ++F V+ + I ++V AK +H
Sbjct: 52 LQELNSGIISLLSDAAFNDSWSSFL---MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLP 108
Query: 500 RISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNIL 559
I + T + TG+ GNKG V + G + +N HL +R +++ IL
Sbjct: 109 YIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRIL 168
Query: 560 RFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQL 619
+ + P + H + WFGD+N+R++ + + + IK + Y L DQL
Sbjct: 169 EMQNCEGRDI-PNILDHDL--IIWFGDMNFRIE--DFGLHFVRESIKNRCYGGLWEKDQL 223
Query: 620 LTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSY 679
++ + F+E + F PTY+F+R + D T K P+W DR+LW+
Sbjct: 224 SIAKKHDPLLREFQEGRLLFPPTYKFDRNSND-------YDTSEKKRKPAWTDRILWRLK 276
Query: 680 ------------PLVH--VVCQSYGSTSDIMTSDHSPVFATFE 708
P H + + Y S SDH PV TF+
Sbjct: 277 RQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFD 319
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 93.6 bits (231), Expect = 1e-18
Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 26/252 (10%)
Query: 471 ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFN 530
++ ++F V+ + I ++V AK +H I + T + TG+ GNKG V +
Sbjct: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63
Query: 531 GTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYR 590
G + +N HL +R +++ IL + + P + H + WFGD+N+R
Sbjct: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDI-PNILDHDL--IIWFGDMNFR 120
Query: 591 VDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTR 650
++ + + + IK + Y L DQL ++ + F+E + F PTY+F+R +
Sbjct: 121 IE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSN 178
Query: 651 DKYAYTKQKATGMKYNLPSWCDRVLWKSY------------PLVH--VVCQSYGSTSDIM 696
D T K P+W DR+LW+ P H + + Y S
Sbjct: 179 D-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYG 231
Query: 697 TSDHSPVFATFE 708
SDH PV TF+
Sbjct: 232 ISDHKPVSGTFD 243
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 93.6 bits (231), Expect = 1e-18
Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 26/252 (10%)
Query: 471 ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFN 530
++ ++F V+ + I ++V AK +H I + T + TG+ GNKG V +
Sbjct: 4 LSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLY 63
Query: 531 GTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYR 590
G + +N HL +R +++ IL + + P + H + WFGD+N+R
Sbjct: 64 GYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDI-PNILDHDL--IIWFGDMNFR 120
Query: 591 VDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTR 650
++ + + + IK + Y L DQL ++ + F+E + F PTY+F+R +
Sbjct: 121 IE--DFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSN 178
Query: 651 DKYAYTKQKATGMKYNLPSWCDRVLWKSY------------PLVH--VVCQSYGSTSDIM 696
D T K P+W DR+LW+ P H + + Y S
Sbjct: 179 D-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYG 231
Query: 697 TSDHSPVFATFE 708
SDH PV TF+
Sbjct: 232 ISDHKPVSGTFD 243
>gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens]
Length = 125
Score = 92.4 bits (228), Expect = 2e-18
Identities = 43/95 (45%), Positives = 60/95 (63%)
Query: 7 HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66
HG I+R E+LL TG DGS+L+R SES+ Y LCVLY +YTYR+ E ++ +
Sbjct: 8 HGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAE 67
Query: 67 ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101
+ GV R+F K+ LI ++K + G+V LQYPV
Sbjct: 68 TAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
>gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens]
Length = 128
Score = 92.4 bits (228), Expect = 2e-18
Identities = 43/95 (45%), Positives = 60/95 (63%)
Query: 7 HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66
HG I+R E+LL TG DGS+L+R SES+ Y LCVLY +YTYR+ E ++ +
Sbjct: 8 HGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAE 67
Query: 67 ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101
+ GV R+F K+ LI ++K + G+V LQYPV
Sbjct: 68 TAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
>gi|54792745 SH2 domain containing 1B [Homo sapiens]
Length = 132
Score = 84.0 bits (206), Expect = 8e-16
Identities = 40/95 (42%), Positives = 57/95 (60%)
Query: 7 HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66
HG +T+ E LL + G DG+FL+R SESI LCV ++N VYTYRI + + +Q
Sbjct: 7 HGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYRIQ 66
Query: 67 ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101
+EG + F L +LI ++K N G+V HL P+
Sbjct: 67 TAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPI 101
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 77.4 bits (189), Expect = 7e-14
Identities = 75/266 (28%), Positives = 97/266 (36%), Gaps = 15/266 (5%)
Query: 922 PPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANR 981
PP P T SP PT + P L + PT P P SPK L + + +
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 982 GLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFP-KPAPRKDQESPK 1040
G P + PS G A T P + P T P L G L++ P K AP +P
Sbjct: 1239 GAPTTPAATPPSPKGGPA--TPPPKGAP-TPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295
Query: 1041 MPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1100
P+ P P G +P + + G P K P P + A
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 1101 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLP-----VKSPAVLHLQHS 1155
S+G P TP S + P P PS TPP+P P +P SPAV+ L
Sbjct: 1356 SKGGPTTPSSKEGPTPP--AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 1156 KGRDYRDNTELPHHGKHRPEEGPPGP 1181
K T + G P +G P
Sbjct: 1414 KA----PATPVTREGAATPSKGDLTP 1435
Score = 62.8 bits (151), Expect = 2e-09
Identities = 61/237 (25%), Positives = 83/237 (35%), Gaps = 24/237 (10%)
Query: 922 PPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANR 981
PP P T P PT + P L + PT P P SPK L + + +
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192
Query: 982 GLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKM 1041
G P + PS G A T + P T +P G + PK AP +P
Sbjct: 1193 GAPTTPAATPPSPKGGLA--TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 1042 PRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRL------RSFTCSSSAEGR- 1094
P+ P P G +P + + P K P P + + +S +G
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 1095 ---AAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPA 1148
AA +G P TP AP P TPP+P P LP +P+
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPP------------AVTPPSPKGTPTLPATTPS 1355
Score = 56.2 bits (134), Expect = 2e-07
Identities = 73/281 (25%), Positives = 89/281 (31%), Gaps = 43/281 (15%)
Query: 923 PMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRG 982
P PL V + + PT P D+P+G S P P + P+ L ++
Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGP--DTPIGNL---SSPVSPVEASFLPENSLSFQGSKD 848
Query: 983 LPPRTQE-SRPSDLGKNA----------GDTLPQEDLPLTKPEMFENPLYGSLSSFPKPA 1031
P T + PS G G TLP ++ P P G + PK A
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908
Query: 1032 P--RKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSS 1089
P SPK R P P P SP T G P+P+
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW------- 961
Query: 1090 SAEGRAAGGDKSQGKPKTPVSSQAPV-PAKRPIKPSRSEINQQTPPTPTP---RPPLPVK 1145
+ AA +G P TP AP PA P P PTP PP P
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 1146 SPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTA 1186
SPA T P P PP P G A
Sbjct: 1022 SPAA--------------TPFPKGASTPPAATPPSPKGSPA 1048
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/276 (26%), Positives = 91/276 (32%), Gaps = 54/276 (19%)
Query: 922 PPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRG------ESPPTPPGQPPISPKKFL 975
PP P T SP P PP +P P G + PT P P SPK L
Sbjct: 1087 PPSPKGGPATPSPKGAP------MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 976 PSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKD 1035
+ +G P + PS G A T P + P T +P G + PK AP
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLA--TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Query: 1036 QESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGP--GKQVPAPRLRSFTCSSSAEG 1093
+ PP P+ G+ +PS A P G P+P+ +
Sbjct: 1199 AAT--------PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK-------GAPTT 1243
Query: 1094 RAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPP---TPTP---RPPLPVKSP 1147
AA +G P TP AP P P + TPP P P PP P P
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPP--AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 1148 AVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLG 1183
A T P P PP P G
Sbjct: 1302 A---------------TSPPKGAPTPPAATPPSPKG 1322
Score = 55.1 bits (131), Expect = 4e-07
Identities = 92/341 (26%), Positives = 114/341 (33%), Gaps = 55/341 (16%)
Query: 882 SLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFG-PPMPLHVKQTLSPDQQPTA 940
S+TS P K +RA P I +P P PP P T SP PT
Sbjct: 912 SMTSSSPKK-----ARATPAP-KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Query: 941 WSYDQP-PKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNA 999
+ P PK P P + PTPP P SPK + + +G P + PS G A
Sbjct: 966 PAATPPSPKGGPATPSP-KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 1000 -------GDTLPQEDLPLTKPEMFENPLYGSLSSFPK---PAPRKDQESPKM-----PRK 1044
T P P K PL + P P+P+ +P + P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
Query: 1045 EPPPCPEPGILSPSIVLTKAQEADRGEGP--GKQVP----APRLRSFTCSSSAEGRAAGG 1098
PP P+ G +PS A P G P AP + T S G A
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 1099 DKSQGKPKTPVSS--------QAPVPAKRPIKPSRSEINQQTPPTP-----TPRPPLPVK 1145
K G P TP ++ P P P P+ TPP+P TP P
Sbjct: 1145 PK--GAPTTPAATPPSPKGGLATPPPKGAPTTPA------ATPPSPKGGLATPSPKGAPT 1196
Query: 1146 SPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTA 1186
+PA G T P P PP P G A
Sbjct: 1197 TPAATPPSPKGGL----ATPSPKGAPTTPAATPPSPKGGLA 1233
Score = 47.4 bits (111), Expect = 8e-05
Identities = 65/284 (22%), Positives = 87/284 (30%), Gaps = 29/284 (10%)
Query: 899 PPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGE 958
PP G+ P + G PP + P PPK +P P
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-- 1315
Query: 959 SPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFEN 1018
+PP+P G P P K P+ PP P T + P T P E
Sbjct: 1316 TPPSPKGSPGTPPPKGAPT------PPAVTPPSPKGTPTLPATTPSSKGGPTT-PSSKEG 1368
Query: 1019 PLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVP 1078
P + + K P SPK P P +P SP+++ ++A P
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP--TSPAVIPLSPKKAPA-------TP 1419
Query: 1079 APRLRSFTCSSSAEGRAAGGDKSQGKPK-TPVSSQAPVPAKRPIKPSRSEINQQTPPTPT 1137
R EG A P TPVS + P + ++ P P
Sbjct: 1420 VTR----------EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 1138 PRPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGP 1181
PP P + PA + S T P P P P
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
Score = 41.2 bits (95), Expect = 0.006
Identities = 53/207 (25%), Positives = 72/207 (34%), Gaps = 34/207 (16%)
Query: 947 PKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQE 1006
PK P P P P PP SPK+ PP ++ S K A P
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPP-SPKE----------PPAPKQVATSSSPKKA----PAT 1496
Query: 1007 DLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMP-RKEPPPCPEPGILSPSIVLTKAQ 1065
P+ P + P P +E P P + P P +LS T A
Sbjct: 1497 PAPMGAP------------TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544
Query: 1066 EADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQ---APVPAKRPIK 1122
+ + P VP+P+ ++ + E A K P S AP P + I
Sbjct: 1545 K-EALIPPAMTVPSPK-KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 1123 PS-RSEINQQTPPTPTPRPPLPVKSPA 1148
P+ S ++ P P PP P K PA
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Score = 39.3 bits (90), Expect = 0.023
Identities = 72/281 (25%), Positives = 101/281 (35%), Gaps = 38/281 (13%)
Query: 919 PFGPPMPLHVKQT---LSPDQQPTAWSYDQP-PKDSPLGPCRGESPPTPPGQPPISPKKF 974
P P L K+T L+P + + P PK +P P E+P TP + SP
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
Query: 975 LPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMF-ENPLYGSLSSFPKPAPR 1033
PST +G P P +L T P T P + +P G + PK P
Sbjct: 1586 TPST-YKGAP------SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPT 1638
Query: 1034 KDQESPKMPRKEPPPCPEPGILSPSIVLTK----AQEADRGEGPGKQVPAPRLRSFTCSS 1089
+P + P SP+ V K +A +G P K+ P L+ +
Sbjct: 1639 SPPVTPSSLKDSP--------TSPASVTCKMGATVPQASKGL-PAKKGPT-ALKEVLVAP 1688
Query: 1090 SAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPP--TPTPRPPLPVKSP 1147
+ E ++ P+T SS PI P S N P T P P LPV+
Sbjct: 1689 APESTPIITAPTRKGPQTKKSS----ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744
Query: 1148 AVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ 1188
+ SK +D + P PE PL A +
Sbjct: 1745 S------SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE 1779
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 67.0 bits (162), Expect = 1e-10
Identities = 67/263 (25%), Positives = 97/263 (36%), Gaps = 17/263 (6%)
Query: 893 EVTSRAPPCSGSSITEIINPNYMGVGPFGP--PMPLHVKQTLSPDQQPTAWSYDQPPKDS 950
E T P S+ + P + P P P P K + ++P + +P +
Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274
Query: 951 PLGPC---RGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQED 1007
P P E PT P +PK+ P+T + P +E P+ K T P+E
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEP 333
Query: 1008 LPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGILSPSIVLTKAQ 1065
P TK P + ++ KPAP +E KEP P EP SP+ A
Sbjct: 334 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP---SPTTPKEPAP 390
Query: 1066 EADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSR 1125
+ + PAP T + SA + K P + + P P P KP+
Sbjct: 391 TTTKSAPTTTKEPAP-----TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAP 444
Query: 1126 SEINQQTPPTPTPRPPLPVKSPA 1148
+ + P TP P K PA
Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPA 467
Score = 58.2 bits (139), Expect = 5e-08
Identities = 65/253 (25%), Positives = 92/253 (36%), Gaps = 27/253 (10%)
Query: 923 PMPLHVKQTLSPDQQP---TAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTA 979
P P K + ++P T S PK+ + +P TP P +PKK P+T
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 980 NRGLPPRTQESRPSDLGKNA-------GDTLPQEDLPLTKPEMFENPLYGSLSSFP-KPA 1031
P +E P+ K A T P+E P T ++ + P KPA
Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 507
Query: 1032 PRKDQE-SPKMPRKEPPPCPE------PGILSPSIVLTKAQEADRGEGP-GKQVPAPRLR 1083
P +E +P P + P PE P +P+ A + P + PAP
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 1084 SFTCSSSAEGRAAGGDKSQG--KPKTPVSSQ-APVPAKRPI-----KPSRSEINQQTPPT 1135
T ++ +G A K PK P + AP K P KP+ + P T
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 1136 PTPRPPLPVKSPA 1148
P P K PA
Sbjct: 628 PKEPAPTTPKEPA 640
Score = 54.3 bits (129), Expect = 7e-07
Identities = 77/322 (23%), Positives = 112/322 (34%), Gaps = 41/322 (12%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAP-PCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
+ + P T K LT P K T P P + + P P P
Sbjct: 480 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-----------PTTPEEPTPTTPE 528
Query: 932 LSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQP-PISPKKFLPSTANRGLPPRTQES 990
P A + + P + +P P E PT P +P P +PK+ P+T P +E
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 991 RPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPC- 1049
P+ K A P+E P T E + ++ KPAP + + KEP P
Sbjct: 587 APTTPKKPA----PKELAPTTTKE-------PTSTTCDKPAPTTPKGTAPTTPKEPAPTT 635
Query: 1050 -PEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTP 1108
EP +P + P K PAP+ + T + + + P TP
Sbjct: 636 PKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTS----DKPAPTTP 689
Query: 1109 VSSQAPVPAKRPIKPSRSEINQQTPPTPTP-----RPPLPVKSPAVLHLQHSKGRDYRDN 1163
AP K P + + TP TP P P K P +H +
Sbjct: 690 -KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748
Query: 1164 TELPHHGKHRPEEGPPGPLGRT 1185
P ++ P+E P P +T
Sbjct: 749 EPTPKALENSPKE-PGVPTTKT 769
Score = 50.1 bits (118), Expect = 1e-05
Identities = 62/288 (21%), Positives = 100/288 (34%), Gaps = 38/288 (13%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTL 932
+++ P T K P + T + P + T P P P K+
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 933 SPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRP 992
+ PT K+ C +P TP G P +PK+ P+T P + + P
Sbjct: 596 PKELAPTT------TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 993 SDLGKNAGDTLPQEDLPL-TKPEMFENPLYGSLSSFPKPAPRKDQE------------SP 1039
+ L K T P++ P P + P + ++ KPAP +E +P
Sbjct: 650 TTL-KEPAPTTPKKPAPKELAPTTTKGP---TSTTSDKPAPTTPKETAPTTPKEPAPTTP 705
Query: 1040 KMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGD 1099
K P P P P S T + + P + P SAE +
Sbjct: 706 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP---------ELSAEPTPKALE 756
Query: 1100 KSQGKP-----KTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPL 1142
S +P KTP +++ + K + ++ + TP T T P +
Sbjct: 757 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTTAAPKM 803
Score = 34.7 bits (78), Expect = 0.56
Identities = 40/158 (25%), Positives = 57/158 (36%), Gaps = 28/158 (17%)
Query: 997 KNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGI 1054
K T P+E T E + + ++ +PAP + +P P KEP P EP
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAP 272
Query: 1055 LSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAP 1114
+P + PAP ++ ++A + P TP AP
Sbjct: 273 TTP------------------KEPAPTTTKEPAPTTT--KSAPTTPKEPAPTTP-KKPAP 311
Query: 1115 VPAKRPIKPSRSEINQQTP--PTPTPRPPLPV--KSPA 1148
K P + E TP P PT + P P K PA
Sbjct: 312 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 67.0 bits (162), Expect = 1e-10
Identities = 67/263 (25%), Positives = 97/263 (36%), Gaps = 17/263 (6%)
Query: 893 EVTSRAPPCSGSSITEIINPNYMGVGPFGP--PMPLHVKQTLSPDQQPTAWSYDQPPKDS 950
E T P S+ + P + P P P P K + ++P + +P +
Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315
Query: 951 PLGPC---RGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQED 1007
P P E PT P +PK+ P+T + P +E P+ K T P+E
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEP 374
Query: 1008 LPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGILSPSIVLTKAQ 1065
P TK P + ++ KPAP +E KEP P EP SP+ A
Sbjct: 375 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP---SPTTPKEPAP 431
Query: 1066 EADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSR 1125
+ + PAP T + SA + K P + + P P P KP+
Sbjct: 432 TTTKSAPTTTKEPAP-----TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAP 485
Query: 1126 SEINQQTPPTPTPRPPLPVKSPA 1148
+ + P TP P K PA
Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPA 508
Score = 58.2 bits (139), Expect = 5e-08
Identities = 65/253 (25%), Positives = 92/253 (36%), Gaps = 27/253 (10%)
Query: 923 PMPLHVKQTLSPDQQP---TAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTA 979
P P K + ++P T S PK+ + +P TP P +PKK P+T
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Query: 980 NRGLPPRTQESRPSDLGKNA-------GDTLPQEDLPLTKPEMFENPLYGSLSSFP-KPA 1031
P +E P+ K A T P+E P T ++ + P KPA
Sbjct: 489 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 548
Query: 1032 PRKDQE-SPKMPRKEPPPCPE------PGILSPSIVLTKAQEADRGEGP-GKQVPAPRLR 1083
P +E +P P + P PE P +P+ A + P + PAP
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 1084 SFTCSSSAEGRAAGGDKSQG--KPKTPVSSQ-APVPAKRPI-----KPSRSEINQQTPPT 1135
T ++ +G A K PK P + AP K P KP+ + P T
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 1136 PTPRPPLPVKSPA 1148
P P K PA
Sbjct: 669 PKEPAPTTPKEPA 681
Score = 54.3 bits (129), Expect = 7e-07
Identities = 77/322 (23%), Positives = 112/322 (34%), Gaps = 41/322 (12%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAP-PCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
+ + P T K LT P K T P P + + P P P
Sbjct: 521 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-----------PTTPEEPTPTTPE 569
Query: 932 LSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQP-PISPKKFLPSTANRGLPPRTQES 990
P A + + P + +P P E PT P +P P +PK+ P+T P +E
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 627
Query: 991 RPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPC- 1049
P+ K A P+E P T E + ++ KPAP + + KEP P
Sbjct: 628 APTTPKKPA----PKELAPTTTKE-------PTSTTCDKPAPTTPKGTAPTTPKEPAPTT 676
Query: 1050 -PEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTP 1108
EP +P + P K PAP+ + T + + + P TP
Sbjct: 677 PKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTS----DKPAPTTP 730
Query: 1109 VSSQAPVPAKRPIKPSRSEINQQTPPTPTP-----RPPLPVKSPAVLHLQHSKGRDYRDN 1163
AP K P + + TP TP P P K P +H +
Sbjct: 731 -KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789
Query: 1164 TELPHHGKHRPEEGPPGPLGRT 1185
P ++ P+E P P +T
Sbjct: 790 EPTPKALENSPKE-PGVPTTKT 810
Score = 50.1 bits (118), Expect = 1e-05
Identities = 62/288 (21%), Positives = 100/288 (34%), Gaps = 38/288 (13%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTL 932
+++ P T K P + T + P + T P P P K+
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 933 SPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRP 992
+ PT K+ C +P TP G P +PK+ P+T P + + P
Sbjct: 637 PKELAPTT------TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 993 SDLGKNAGDTLPQEDLPL-TKPEMFENPLYGSLSSFPKPAPRKDQE------------SP 1039
+ L K T P++ P P + P + ++ KPAP +E +P
Sbjct: 691 TTL-KEPAPTTPKKPAPKELAPTTTKGP---TSTTSDKPAPTTPKETAPTTPKEPAPTTP 746
Query: 1040 KMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGD 1099
K P P P P S T + + P + P SAE +
Sbjct: 747 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP---------ELSAEPTPKALE 797
Query: 1100 KSQGKP-----KTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPL 1142
S +P KTP +++ + K + ++ + TP T T P +
Sbjct: 798 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTTAAPKM 844
Score = 34.7 bits (78), Expect = 0.56
Identities = 40/158 (25%), Positives = 57/158 (36%), Gaps = 28/158 (17%)
Query: 997 KNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGI 1054
K T P+E T E + + ++ +PAP + +P P KEP P EP
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAP 313
Query: 1055 LSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAP 1114
+P + PAP ++ ++A + P TP AP
Sbjct: 314 TTP------------------KEPAPTTTKEPAPTTT--KSAPTTPKEPAPTTP-KKPAP 352
Query: 1115 VPAKRPIKPSRSEINQQTP--PTPTPRPPLPV--KSPA 1148
K P + E TP P PT + P P K PA
Sbjct: 353 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 67.0 bits (162), Expect = 1e-10
Identities = 67/263 (25%), Positives = 97/263 (36%), Gaps = 17/263 (6%)
Query: 893 EVTSRAPPCSGSSITEIINPNYMGVGPFGP--PMPLHVKQTLSPDQQPTAWSYDQPPKDS 950
E T P S+ + P + P P P P K + ++P + +P +
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 951 PLGPC---RGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQED 1007
P P E PT P +PK+ P+T + P +E P+ K T P+E
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEP 426
Query: 1008 LPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGILSPSIVLTKAQ 1065
P TK P + ++ KPAP +E KEP P EP SP+ A
Sbjct: 427 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP---SPTTPKEPAP 483
Query: 1066 EADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSR 1125
+ + PAP T + SA + K P + + P P P KP+
Sbjct: 484 TTTKSAPTTTKEPAP-----TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAP 537
Query: 1126 SEINQQTPPTPTPRPPLPVKSPA 1148
+ + P TP P K PA
Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPA 560
Score = 58.2 bits (139), Expect = 5e-08
Identities = 65/253 (25%), Positives = 92/253 (36%), Gaps = 27/253 (10%)
Query: 923 PMPLHVKQTLSPDQQP---TAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTA 979
P P K + ++P T S PK+ + +P TP P +PKK P+T
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540
Query: 980 NRGLPPRTQESRPSDLGKNA-------GDTLPQEDLPLTKPEMFENPLYGSLSSFP-KPA 1031
P +E P+ K A T P+E P T ++ + P KPA
Sbjct: 541 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 600
Query: 1032 PRKDQE-SPKMPRKEPPPCPE------PGILSPSIVLTKAQEADRGEGP-GKQVPAPRLR 1083
P +E +P P + P PE P +P+ A + P + PAP
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 1084 SFTCSSSAEGRAAGGDKSQG--KPKTPVSSQ-APVPAKRPI-----KPSRSEINQQTPPT 1135
T ++ +G A K PK P + AP K P KP+ + P T
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 1136 PTPRPPLPVKSPA 1148
P P K PA
Sbjct: 721 PKEPAPTTPKEPA 733
Score = 54.3 bits (129), Expect = 7e-07
Identities = 77/322 (23%), Positives = 112/322 (34%), Gaps = 41/322 (12%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAP-PCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
+ + P T K LT P K T P P + + P P P
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-----------PTTPEEPTPTTPE 621
Query: 932 LSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQP-PISPKKFLPSTANRGLPPRTQES 990
P A + + P + +P P E PT P +P P +PK+ P+T P +E
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 991 RPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPC- 1049
P+ K A P+E P T E + ++ KPAP + + KEP P
Sbjct: 680 APTTPKKPA----PKELAPTTTKE-------PTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728
Query: 1050 -PEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTP 1108
EP +P + P K PAP+ + T + + + P TP
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTS----DKPAPTTP 782
Query: 1109 VSSQAPVPAKRPIKPSRSEINQQTPPTPTP-----RPPLPVKSPAVLHLQHSKGRDYRDN 1163
AP K P + + TP TP P P K P +H +
Sbjct: 783 -KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 1164 TELPHHGKHRPEEGPPGPLGRT 1185
P ++ P+E P P +T
Sbjct: 842 EPTPKALENSPKE-PGVPTTKT 862
Score = 50.1 bits (118), Expect = 1e-05
Identities = 62/288 (21%), Positives = 100/288 (34%), Gaps = 38/288 (13%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTL 932
+++ P T K P + T + P + T P P P K+
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 688
Query: 933 SPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRP 992
+ PT K+ C +P TP G P +PK+ P+T P + + P
Sbjct: 689 PKELAPTT------TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 993 SDLGKNAGDTLPQEDLPL-TKPEMFENPLYGSLSSFPKPAPRKDQE------------SP 1039
+ L K T P++ P P + P + ++ KPAP +E +P
Sbjct: 743 TTL-KEPAPTTPKKPAPKELAPTTTKGP---TSTTSDKPAPTTPKETAPTTPKEPAPTTP 798
Query: 1040 KMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGD 1099
K P P P P S T + + P + P SAE +
Sbjct: 799 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP---------ELSAEPTPKALE 849
Query: 1100 KSQGKP-----KTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPL 1142
S +P KTP +++ + K + ++ + TP T T P +
Sbjct: 850 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTTAAPKM 896
Score = 34.7 bits (78), Expect = 0.56
Identities = 40/158 (25%), Positives = 57/158 (36%), Gaps = 28/158 (17%)
Query: 997 KNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGI 1054
K T P+E T E + + ++ +PAP + +P P KEP P EP
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAP 365
Query: 1055 LSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAP 1114
+P + PAP ++ ++A + P TP AP
Sbjct: 366 TTP------------------KEPAPTTTKEPAPTTT--KSAPTTPKEPAPTTP-KKPAP 404
Query: 1115 VPAKRPIKPSRSEINQQTP--PTPTPRPPLPV--KSPA 1148
K P + E TP P PT + P P K PA
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 67.0 bits (162), Expect = 1e-10
Identities = 67/263 (25%), Positives = 97/263 (36%), Gaps = 17/263 (6%)
Query: 893 EVTSRAPPCSGSSITEIINPNYMGVGPFGP--PMPLHVKQTLSPDQQPTAWSYDQPPKDS 950
E T P S+ + P + P P P P K + ++P + +P +
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 951 PLGPC---RGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQED 1007
P P E PT P +PK+ P+T + P +E P+ K T P+E
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEP 467
Query: 1008 LPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGILSPSIVLTKAQ 1065
P TK P + ++ KPAP +E KEP P EP SP+ A
Sbjct: 468 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP---SPTTPKEPAP 524
Query: 1066 EADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSR 1125
+ + PAP T + SA + K P + + P P P KP+
Sbjct: 525 TTTKSAPTTTKEPAP-----TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT-TPKKPAP 578
Query: 1126 SEINQQTPPTPTPRPPLPVKSPA 1148
+ + P TP P K PA
Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPA 601
Score = 58.2 bits (139), Expect = 5e-08
Identities = 65/253 (25%), Positives = 92/253 (36%), Gaps = 27/253 (10%)
Query: 923 PMPLHVKQTLSPDQQP---TAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTA 979
P P K + ++P T S PK+ + +P TP P +PKK P+T
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581
Query: 980 NRGLPPRTQESRPSDLGKNA-------GDTLPQEDLPLTKPEMFENPLYGSLSSFP-KPA 1031
P +E P+ K A T P+E P T ++ + P KPA
Sbjct: 582 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 641
Query: 1032 PRKDQE-SPKMPRKEPPPCPE------PGILSPSIVLTKAQEADRGEGP-GKQVPAPRLR 1083
P +E +P P + P PE P +P+ A + P + PAP
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 1084 SFTCSSSAEGRAAGGDKSQG--KPKTPVSSQ-APVPAKRPI-----KPSRSEINQQTPPT 1135
T ++ +G A K PK P + AP K P KP+ + P T
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 1136 PTPRPPLPVKSPA 1148
P P K PA
Sbjct: 762 PKEPAPTTPKEPA 774
Score = 54.3 bits (129), Expect = 7e-07
Identities = 77/322 (23%), Positives = 112/322 (34%), Gaps = 41/322 (12%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAP-PCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
+ + P T K LT P K T P P + + P P P
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-----------PTTPEEPTPTTPE 662
Query: 932 LSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQP-PISPKKFLPSTANRGLPPRTQES 990
P A + + P + +P P E PT P +P P +PK+ P+T P +E
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 991 RPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPC- 1049
P+ K A P+E P T E + ++ KPAP + + KEP P
Sbjct: 721 APTTPKKPA----PKELAPTTTKE-------PTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769
Query: 1050 -PEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTP 1108
EP +P + P K PAP+ + T + + + P TP
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTS----DKPAPTTP 823
Query: 1109 VSSQAPVPAKRPIKPSRSEINQQTPPTPTP-----RPPLPVKSPAVLHLQHSKGRDYRDN 1163
AP K P + + TP TP P P K P +H +
Sbjct: 824 -KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 1164 TELPHHGKHRPEEGPPGPLGRT 1185
P ++ P+E P P +T
Sbjct: 883 EPTPKALENSPKE-PGVPTTKT 903
Score = 50.1 bits (118), Expect = 1e-05
Identities = 62/288 (21%), Positives = 100/288 (34%), Gaps = 38/288 (13%)
Query: 873 ESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTL 932
+++ P T K P + T + P + T P P P K+
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 729
Query: 933 SPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRP 992
+ PT K+ C +P TP G P +PK+ P+T P + + P
Sbjct: 730 PKELAPTT------TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 993 SDLGKNAGDTLPQEDLPL-TKPEMFENPLYGSLSSFPKPAPRKDQE------------SP 1039
+ L K T P++ P P + P + ++ KPAP +E +P
Sbjct: 784 TTL-KEPAPTTPKKPAPKELAPTTTKGP---TSTTSDKPAPTTPKETAPTTPKEPAPTTP 839
Query: 1040 KMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGD 1099
K P P P P S T + + P + P SAE +
Sbjct: 840 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP---------ELSAEPTPKALE 890
Query: 1100 KSQGKP-----KTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPL 1142
S +P KTP +++ + K + ++ + TP T T P +
Sbjct: 891 NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTTAAPKM 937
Score = 34.7 bits (78), Expect = 0.56
Identities = 40/158 (25%), Positives = 57/158 (36%), Gaps = 28/158 (17%)
Query: 997 KNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPP--CPEPGI 1054
K T P+E T E + + ++ +PAP + +P P KEP P EP
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAP 406
Query: 1055 LSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAP 1114
+P + PAP ++ ++A + P TP AP
Sbjct: 407 TTP------------------KEPAPTTTKEPAPTTT--KSAPTTPKEPAPTTP-KKPAP 445
Query: 1115 VPAKRPIKPSRSEINQQTP--PTPTPRPPLPV--KSPA 1148
K P + E TP P PT + P P K PA
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 63.5 bits (153), Expect = 1e-09
Identities = 82/290 (28%), Positives = 104/290 (35%), Gaps = 45/290 (15%)
Query: 916 GVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPC----RGESPPTPPGQPPISP 971
G P GPP P Q P Q PP P GP + SP +PPG+P P
Sbjct: 44 GNKPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 101
Query: 972 KKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPA 1031
P N+ P +P G+ PQ P KP+ P G S P+
Sbjct: 102 ----PQGGNQPQGPPPPPGKPQGPPPQGGNR-PQGPPPPGKPQ--GPPPQGDKSRSPRSP 154
Query: 1032 PRKDQESP----KMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGP---GK-QVPAPRLR 1083
P K Q P P+ PPP +P P Q + +GP GK Q P P+
Sbjct: 155 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-------QGGKKPQGPPPPGKPQGPPPQGD 207
Query: 1084 SFTCSSSAEGRAAG-----GDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTP 1138
S S G+ G G++ QG P P Q P P + KP Q PP P
Sbjct: 208 KSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-PPQGGNKP------QGPPPPGKP 260
Query: 1139 RPPLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRTAMQ 1188
+ P PA + R + P + +GPP P G Q
Sbjct: 261 QGP-----PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 305
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/277 (26%), Positives = 104/277 (37%), Gaps = 74/277 (26%)
Query: 927 HVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPR 986
++ + +S ++ P+ + P SP G + + PP PPG+P +G PP+
Sbjct: 18 NLNEDVSQEESPSLIA-GNPQGPSPQGGNKPQGPPPPPGKP-------------QGPPPQ 63
Query: 987 TQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESP----KMP 1042
G PQ P KP+ P G S P+ P K Q P P
Sbjct: 64 -------------GGNKPQGPPPPGKPQ--GPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 108
Query: 1043 RKEPPPCPEPGILSPSIVLTKAQEADRGEG---PGK-QVPAPRLRSFTCSSSAEGR---- 1094
+ PPP +P P Q +R +G PGK Q P P+ S G+
Sbjct: 109 QGPPPPPGKPQGPPP-------QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161
Query: 1095 -AAGGDKSQGKPKTPVSSQAPVP--AKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLH 1151
GG++ QG P P Q P P K+P Q PP P+ P P
Sbjct: 162 PPQGGNQPQGPPPPPGKPQGPPPQGGKKP---------QGPPPPGKPQGPPP-------- 204
Query: 1152 LQHSKGRDYRDNTELPH----HGKHRPEEGPPGPLGR 1184
Q K R + P G ++P +GPP P G+
Sbjct: 205 -QGDKSRSSQSPPGKPQGPPPQGGNQP-QGPPPPPGK 239
Score = 53.9 bits (128), Expect = 9e-07
Identities = 70/250 (28%), Positives = 86/250 (34%), Gaps = 48/250 (19%)
Query: 912 PNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPC----RGESPPTPPGQP 967
P G P GPP P Q P Q PP P GP + SP +PPG+P
Sbjct: 101 PPQGGNQPQGPPPPPGKPQ--GPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 158
Query: 968 PISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSF 1027
P + PP + P GK PQ P KP+ P G S
Sbjct: 159 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK-----PQGPPPPGKPQ--GPPPQGDKSRS 211
Query: 1028 PKPAPRKDQESP----KMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGP---GKQVPAP 1080
+ P K Q P P+ PPP +P P Q ++ +GP GK P
Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-------QGGNKPQGPPPPGKPQGPP 264
Query: 1081 RLRSFTCSSSAEGRAAGGDKSQ------GKPKTPVSSQAPVPAKRPIKPSRSEINQQTPP 1134
A GG KSQ GKP+ P + P P + Q PP
Sbjct: 265 --------------AQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310
Query: 1135 TPTPR-PPLP 1143
P+ PP P
Sbjct: 311 AGQPQGPPRP 320
Score = 38.9 bits (89), Expect = 0.029
Identities = 48/192 (25%), Positives = 63/192 (32%), Gaps = 24/192 (12%)
Query: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
D+S P++ P + PP G P G P GPP P +
Sbjct: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---PPQGGKKPQGPPPP---GKP 199
Query: 932 LSPDQQPTAWSYDQPPKDSPLGPC-----RGESPPTPPGQPPISPKKFLPSTANRGL--- 983
P Q Q P P GP + + PP PPG+P P P N+
Sbjct: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP----PQGGNKPQGPP 255
Query: 984 PPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPR 1043
PP + P+ G + P P+ N G P PA Q+ P
Sbjct: 256 PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP----PPPAGGNPQQPQAPPA 311
Query: 1044 KEP--PPCPEPG 1053
+P PP P G
Sbjct: 312 GQPQGPPRPPQG 323
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 62.8 bits (151), Expect = 2e-09
Identities = 77/271 (28%), Positives = 100/271 (36%), Gaps = 51/271 (18%)
Query: 919 PFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPST 978
P GPP P Q+ P +P +P P G + + PP PG+P P +
Sbjct: 78 PEGPP-PQGGNQSQGPPPRP-----GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQ--GGN 129
Query: 979 ANRGLPPRT--QESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQ 1036
++G PPR E P G + P+ P P P G+ S P P P K +
Sbjct: 130 QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP-----PQGGNQSQGPPPHPGKPE 184
Query: 1037 ESPKMPRKEPP-PCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRA 1095
P + P P PG K + G Q P PR EG
Sbjct: 185 GPPPQGGNQSQGPPPRPG---------KPEGPPPQGGNQSQGPPPR------PGKPEGPP 229
Query: 1096 A-GGDKSQGKPKTPVSSQAPVP-----AKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAV 1149
+ GG+K QG P P Q P P +RP P R Q PP P P P+ PA
Sbjct: 230 SQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR----PQGPPPPGGNPQQPLPPPA- 284
Query: 1150 LHLQHSKGRDYRDNTELPHHGK-HRPEEGPP 1179
G+ + P G+ HRP +G P
Sbjct: 285 -------GKP-QGPPPPPQGGRPHRPPQGQP 307
Score = 53.1 bits (126), Expect = 2e-06
Identities = 67/260 (25%), Positives = 96/260 (36%), Gaps = 41/260 (15%)
Query: 928 VKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPR- 986
+ + +S ++ P+ S +P P G + + P PPG+P P + ++G PPR
Sbjct: 19 LNEDVSQEESPSVIS-GKPEGRRPQGGNQPQRTPPPPGKPEGRPPQ--GGNQSQGPPPRP 75
Query: 987 -TQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQ-ESPKMPRK 1044
E P G + P+ P +P P G+ S P P P K + P+ +
Sbjct: 76 GKPEGPPPQGGNQSQGPPPRPGKPEGQP-----PQGGNQSQGPPPRPGKPEGPPPQGGNQ 130
Query: 1045 EPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEG-RAAGGDKSQG 1103
P P PG K + G Q P PR EG GG++SQG
Sbjct: 131 SQGPPPRPG---------KPEGPPPQGGNQSQGPPPR------PGKPEGPPPQGGNQSQG 175
Query: 1104 KPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDN 1163
P P + P P NQ P P P P + P S+G R
Sbjct: 176 PPPHPGKPEGPPPQGG---------NQSQGPPPRPGKP---EGPPPQGGNQSQGPPPRPG 223
Query: 1164 TE--LPHHGKHRPEEGPPGP 1181
P G ++P+ PP P
Sbjct: 224 KPEGPPSQGGNKPQGPPPHP 243
Score = 32.0 bits (71), Expect = 3.6
Identities = 33/121 (27%), Positives = 42/121 (34%), Gaps = 13/121 (10%)
Query: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
++S GP P + + PP G P+ G P GPP H +
Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP---PSQGGNKPQGPPP--HPGKP 246
Query: 932 LSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESR 991
P Q PP P GP PP Q P+ P P+ +G PP Q R
Sbjct: 247 QGPPPQEGNKPQRPPPPGRPQGP----PPPGGNPQQPLPP----PAGKPQGPPPPPQGGR 298
Query: 992 P 992
P
Sbjct: 299 P 299
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/113 (37%), Positives = 56/113 (49%), Gaps = 8/113 (7%)
Query: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64
W HG ++R+ AE LLS +G +GSFLVR SES ++ + Y VY YRI D K
Sbjct: 127 WYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 185
Query: 65 VQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDT--GDDPEED 115
V + F L +L+ + GL+T L YP P + T G P D
Sbjct: 186 VSSESR-----FNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYD 233
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/113 (37%), Positives = 56/113 (49%), Gaps = 8/113 (7%)
Query: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64
W HG ++R+ AE LLS +G +GSFLVR SES ++ + Y VY YRI D K
Sbjct: 146 WYHGPVSRNAAEYLLS-SGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 204
Query: 65 VQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDT--GDDPEED 115
V + F L +L+ + GL+T L YP P + T G P D
Sbjct: 205 VSSESR-----FNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYD 252
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/98 (40%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64
W HG ++RS AE LLS +GSFLVR SES ++ + Y VY YRI D K
Sbjct: 158 WYHGPVSRSAAEYLLSSL-INGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 216
Query: 65 VQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVP 102
V A F+ L +L+ + GLVT L YP P
Sbjct: 217 VTAESR-----FSTLAELVHHHSTVADGLVTTLHYPAP 249
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/98 (40%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 5 WNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFT 64
W HG ++RS AE LLS +GSFLVR SES ++ + Y VY YRI D K
Sbjct: 173 WYHGPVSRSAAEYLLSSL-INGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 65 VQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVP 102
V A F+ L +L+ + GLVT L YP P
Sbjct: 232 VTAESR-----FSTLAELVHHHSTVADGLVTTLHYPAP 264
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,877,090
Number of Sequences: 37866
Number of extensions: 3190441
Number of successful extensions: 21141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 1029
Number of HSP's that attempted gapping in prelim test: 13919
Number of HSP's gapped (non-prelim): 5429
length of query: 1188
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1075
effective length of database: 13,968,660
effective search space: 15016309500
effective search space used: 15016309500
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.