Guide to the Human Genome
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Name: SH2D1B Sequence: fasta or formatted (132aa) NCBI GI: 54792745
Description:

SH2 domain containing 1B

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             0.8          1           1
 C cysteine            2.3          3           1
 D aspartate           4.5          6           1
 E glutamate           6.8          9           1
 F phenylalanine       4.5          6           1
 G glycine             6.1          8           1
 H histidine           2.3          3           1
 I isoleucine          4.5          6           1
 K lysine              8.3         11           1
 L leucine            13.6         18           3
 M methionine          1.5          2           1
 N asparagine          3.8          5           1
 P proline             6.1          8           1
 Q glutamine           3.0          4           1
 R arginine            6.1          8           1
 S serine              7.6         10           1
 T threonine           4.5          6           1
 V valine              7.6         10           2
 W tryptophan          0.8          1           1
 Y tyrosine            5.3          7           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH2 domain containing 1B 
SH2D1A                0.335   SH2 domain protein 1A isoform 2 
SH2D1A                0.327   SH2 domain protein 1A isoform 1 
INPPL1                0.258   inositol polyphosphate phosphatase-like 1 
INPP5D                0.238   SH2 containing inositol phosphatase isoform b 
INPP5D                0.238   SH2 containing inositol phosphatase isoform a 
DAPP1                 0.109   dual adaptor of phosphotyrosine and 3-phosphoinosit...
GRAP                  0.109   GRB2-related adaptor protein 
GRB2                  0.109   growth factor receptor-bound protein 2 isoform 1 [Hom...
FRK                   0.109   fyn-related kinase 
LCK                   0.105   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.105   lymphocyte-specific protein tyrosine kinase precurs...
ABL1                  0.105   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.105   c-abl oncogene 1, receptor tyrosine kinase isoform b...
CSK                   0.105   c-src tyrosine kinase 
CSK                   0.105   c-src tyrosine kinase 
ABL2                  0.093   arg tyrosine kinase isoform c 
ABL2                  0.093   arg tyrosine kinase isoform b 
ABL2                  0.093   arg tyrosine kinase isoform e 
ABL2                  0.093   arg tyrosine kinase isoform d 
ABL2                  0.093   arg tyrosine kinase isoform a 
PTPN11                0.089   protein tyrosine phosphatase, non-receptor type 11 [...
MATK                  0.089   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.089   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.089   megakaryocyte-associated tyrosine kinase isoform a [...
SYK                   0.085   spleen tyrosine kinase isoform 2 
SYK                   0.085   spleen tyrosine kinase isoform 1 
HCK                   0.085   hemopoietic cell kinase isoform p61HCK 
BCAR3                 0.081   breast cancer antiestrogen resistance 3 
SRC                   0.081   proto-oncogene tyrosine-protein kinase SRC 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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