Guide to the Human Genome
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Name: SH2D1A Sequence: fasta or formatted (128aa) NCBI GI: 4506923
Description:

SH2 domain protein 1A isoform 1

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [125aa] SH2 domain protein 1A isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2          8           1
 C cysteine            2.3          3           1
 D aspartate           4.7          6           1
 E glutamate           5.5          7           1
 F phenylalanine       1.6          2           1
 G glycine             8.6         11           1
 H histidine           2.3          3           1
 I isoleucine          5.5          7           1
 K lysine              7.0          9           2
 L leucine             8.6         11           3
 M methionine          0.8          1           1
 N asparagine          0.8          1           1
 P proline             5.5          7           1
 Q glutamine           3.9          5           1
 R arginine            5.5          7           1
 S serine              8.6         11           2
 T threonine           7.0          9           2
 V valine              7.8         10           1
 W tryptophan          0.8          1           1
 Y tyrosine            7.0          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH2 domain protein 1A isoform 1 
SH2D1A                0.950   SH2 domain protein 1A isoform 2 
SH2D1B                0.340   SH2 domain containing 1B 
INPP5D                0.282   SH2 containing inositol phosphatase isoform b 
INPP5D                0.282   SH2 containing inositol phosphatase isoform a 
INPPL1                0.256   inositol polyphosphate phosphatase-like 1 
ABL1                  0.147   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.147   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.126   arg tyrosine kinase isoform c 
ABL2                  0.126   arg tyrosine kinase isoform b 
ABL2                  0.126   arg tyrosine kinase isoform e 
ABL2                  0.126   arg tyrosine kinase isoform d 
ABL2                  0.126   arg tyrosine kinase isoform a 
DAPP1                 0.105   dual adaptor of phosphotyrosine and 3-phosphoinosit...
SYK                   0.101   spleen tyrosine kinase isoform 2 
SYK                   0.101   spleen tyrosine kinase isoform 1 
FRK                   0.088   fyn-related kinase 
CSK                   0.084   c-src tyrosine kinase 
CSK                   0.084   c-src tyrosine kinase 
ITK                   0.080   IL2-inducible T-cell kinase 
GRB10                 0.080   growth factor receptor-bound protein 10 isoform c [H...
GRB10                 0.080   growth factor receptor-bound protein 10 isoform c [H...
GRB10                 0.080   growth factor receptor-bound protein 10 isoform b [H...
GRB10                 0.080   growth factor receptor-bound protein 10 isoform a [H...
GRAP                  0.076   GRB2-related adaptor protein 
CHN2                  0.071   beta chimerin isoform 2 
CHN1                  0.071   chimerin (chimaerin) 1 isoform a 
CHN1                  0.071   chimerin (chimaerin) 1 isoform b 
RASA1                 0.067   RAS p21 protein activator 1 isoform 1 
RASA1                 0.067   RAS p21 protein activator 1 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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