Guide to the Human Genome
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Name: SH2D1A Sequence: fasta or formatted (125aa) NCBI GI: 169234945
Description:

SH2 domain protein 1A isoform 2

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [128aa] SH2 domain protein 1A isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.4          8           1
 C cysteine            2.4          3           1
 D aspartate           4.8          6           1
 E glutamate           5.6          7           1
 F phenylalanine       1.6          2           1
 G glycine             8.0         10           1
 H histidine           2.4          3           1
 I isoleucine          5.6          7           1
 K lysine              7.2          9           2
 L leucine             8.8         11           3
 M methionine          0.8          1           1
 N asparagine          0.8          1           1
 P proline             5.6          7           1
 Q glutamine           4.0          5           1
 R arginine            5.6          7           1
 S serine              8.8         11           2
 T threonine           5.6          7           1
 V valine              8.0         10           1
 W tryptophan          0.8          1           1
 Y tyrosine            7.2          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH2 domain protein 1A isoform 2 
SH2D1A                0.974   SH2 domain protein 1A isoform 1 
SH2D1B                0.358   SH2 domain containing 1B 
INPP5D                0.289   SH2 containing inositol phosphatase isoform b 
INPP5D                0.289   SH2 containing inositol phosphatase isoform a 
INPPL1                0.263   inositol polyphosphate phosphatase-like 1 
ABL1                  0.151   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.151   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.129   arg tyrosine kinase isoform c 
ABL2                  0.129   arg tyrosine kinase isoform b 
ABL2                  0.129   arg tyrosine kinase isoform e 
ABL2                  0.129   arg tyrosine kinase isoform d 
ABL2                  0.129   arg tyrosine kinase isoform a 
DAPP1                 0.108   dual adaptor of phosphotyrosine and 3-phosphoinosit...
SYK                   0.103   spleen tyrosine kinase isoform 2 
SYK                   0.103   spleen tyrosine kinase isoform 1 
FRK                   0.091   fyn-related kinase 
CSK                   0.086   c-src tyrosine kinase 
CSK                   0.086   c-src tyrosine kinase 
ITK                   0.086   IL2-inducible T-cell kinase 
GRB10                 0.082   growth factor receptor-bound protein 10 isoform c [H...
GRB10                 0.082   growth factor receptor-bound protein 10 isoform c [H...
GRB10                 0.082   growth factor receptor-bound protein 10 isoform b [H...
GRB10                 0.082   growth factor receptor-bound protein 10 isoform a [H...
GRAP                  0.078   GRB2-related adaptor protein 
SRC                   0.073   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.073   proto-oncogene tyrosine-protein kinase SRC 
CHN2                  0.073   beta chimerin isoform 2 
CHN1                  0.073   chimerin (chimaerin) 1 isoform a 
CHN1                  0.073   chimerin (chimaerin) 1 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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