Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40217843
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40217843 cartilage oligomeric matrix protein precursor [Homo
sapiens]
(757 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40217843 cartilage oligomeric matrix protein precursor [Homo ... 1633 0.0
gi|31543806 thrombospondin 4 precursor [Homo sapiens] 1133 0.0
gi|6005902 thrombospondin 3 precursor [Homo sapiens] 1046 0.0
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 750 0.0
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 747 0.0
gi|24430141 fibrillin 1 precursor [Homo sapiens] 112 1e-24
gi|110347437 latent transforming growth factor beta binding prot... 100 7e-21
gi|110347412 latent transforming growth factor beta binding prot... 100 7e-21
gi|110347431 latent transforming growth factor beta binding prot... 100 7e-21
gi|126091152 cubilin [Homo sapiens] 95 3e-19
gi|115298674 nidogen 1 precursor [Homo sapiens] 90 9e-18
gi|66346695 fibrillin 2 precursor [Homo sapiens] 86 2e-16
gi|61743978 stabilin 1 precursor [Homo sapiens] 85 2e-16
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 85 3e-16
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 84 4e-16
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 84 4e-16
gi|4557733 latent transforming growth factor beta binding protei... 84 4e-16
gi|56237021 fibrillin 3 precursor [Homo sapiens] 84 4e-16
gi|144953895 nidogen 2 precursor [Homo sapiens] 83 1e-15
gi|118572606 hemicentin 1 [Homo sapiens] 82 2e-15
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 82 2e-15
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 82 2e-15
gi|34734066 fibulin 1 isoform D [Homo sapiens] 82 2e-15
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 82 2e-15
gi|134244285 Notch homolog 3 [Homo sapiens] 81 4e-15
gi|56550049 uromodulin precursor [Homo sapiens] 80 7e-15
gi|59850812 uromodulin precursor [Homo sapiens] 80 7e-15
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 79 1e-14
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 79 1e-14
gi|40807489 egf-like module containing, mucin-like, hormone rece... 79 1e-14
>gi|40217843 cartilage oligomeric matrix protein precursor [Homo
sapiens]
Length = 757
Score = 1633 bits (4229), Expect = 0.0
Identities = 757/757 (100%), Positives = 757/757 (100%)
Query: 1 MVPDTACVLLLTLAALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREIT 60
MVPDTACVLLLTLAALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREIT
Sbjct: 1 MVPDTACVLLLTLAALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREIT 60
Query: 61 FLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTG 120
FLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTG
Sbjct: 61 FLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTG 120
Query: 121 NGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTD 180
NGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTD
Sbjct: 121 NGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTD 180
Query: 181 INECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEH 240
INECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEH
Sbjct: 181 INECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEH 240
Query: 241 ADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ 300
ADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ
Sbjct: 241 ADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ 300
Query: 301 EDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK 360
EDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK
Sbjct: 301 EDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK 360
Query: 361 DTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQAD 420
DTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQAD
Sbjct: 361 DTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQAD 420
Query: 421 VDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDS 480
VDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDS
Sbjct: 421 VDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDS 480
Query: 481 RDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLD 540
RDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLD
Sbjct: 481 RDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLD 540
Query: 541 PEGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFI 600
PEGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFI
Sbjct: 541 PEGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFI 600
Query: 601 FGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDT 660
FGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDT
Sbjct: 601 FGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDT 660
Query: 661 ESQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGG 720
ESQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGG
Sbjct: 661 ESQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGG 720
Query: 721 RLGVFCFSQENIIWANLRYRCNDTIPEDYETHQLRQA 757
RLGVFCFSQENIIWANLRYRCNDTIPEDYETHQLRQA
Sbjct: 721 RLGVFCFSQENIIWANLRYRCNDTIPEDYETHQLRQA 757
>gi|31543806 thrombospondin 4 precursor [Homo sapiens]
Length = 961
Score = 1133 bits (2930), Expect = 0.0
Identities = 521/752 (69%), Positives = 601/752 (79%), Gaps = 24/752 (3%)
Query: 16 LGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREITFLKNTVMECDACG-- 73
L A+G G D Q L ++ + N L +V++LLRQQV+E +FL+NT+ EC ACG
Sbjct: 211 LAATGTG------DFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPL 264
Query: 74 -MQQSVRTGL-------PSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHC 125
Q + + P RP C CF GV C + G +CGPCP G+TGNG C
Sbjct: 265 KFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC 324
Query: 126 TDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE 185
DV+EC HPC+P V CIN SPGFRC+ACP G++GP QGVG++FAK+NKQVCTDI+EC
Sbjct: 325 IDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR 384
Query: 186 TGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVL 245
G CVPNS+C+NT GS++CGPC+PG+ GDQ GC +A+R C + + C +A C+
Sbjct: 385 NGA--CVPNSICVNTLGSYRCGPCKPGYTGDQIRGC--KAERNCRNPELNPCSVNAQCIE 440
Query: 246 ERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDR 305
ER G +CVC VGWAG+G +CG+D D+D +PDE+L C R C+KDNC VPNSGQED DR
Sbjct: 441 ERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR 500
Query: 306 DGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQD 365
DGIGDACD DADGDG+ NE+DNC L+ N DQRN+D+D +GDACDNC S N+DQKDTD D
Sbjct: 501 DGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGD 560
Query: 366 GRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDF 425
GRGDACDDD+DGD I+N DNCP+ PN DQ+D DGDG+GDACD+CP SNP+Q+DVD+D
Sbjct: 561 GRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDL 620
Query: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD----SR 481
VGD+CD++QD DGDGHQDS DNCPTV NSAQ D+D DG GD CDDDDDNDG+PD
Sbjct: 621 VGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGP 680
Query: 482 DNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDP 541
DNCRLVPNP QED++ DGVGD+C+ DFD D+V+D+IDVCPENAEVTLTDFRA+QTVVLDP
Sbjct: 681 DNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDP 740
Query: 542 EGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIF 601
EGDAQIDPNWVVLNQG EIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNT TDDDYAGFIF
Sbjct: 741 EGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIF 800
Query: 602 GYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTE 661
GYQDSSSFYVVMWKQ EQTYWQA PFRAVAEPGIQLKAVKS TGPGE LRN+LWHTGDT
Sbjct: 801 GYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTS 860
Query: 662 SQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGR 721
QVRLLWKD RNVGWKDK SYRWFLQHRPQVGYIRVRFYEG ELVADS V +DTTMRGGR
Sbjct: 861 DQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGR 920
Query: 722 LGVFCFSQENIIWANLRYRCNDTIPEDYETHQ 753
LGVFCFSQENIIW+NL+YRCNDTIPED++ Q
Sbjct: 921 LGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQ 952
>gi|6005902 thrombospondin 3 precursor [Homo sapiens]
Length = 956
Score = 1046 bits (2706), Expect = 0.0
Identities = 481/738 (65%), Positives = 572/738 (77%), Gaps = 25/738 (3%)
Query: 26 LGSDLGPQ---MLRELQETNAALQDVRELLRQQVREITFLKNTVMECDACGMQQSVRTGL 82
L S LG Q ++ +L N L ++R+ +R QV+E++ ++NT+MEC CG +
Sbjct: 220 LHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS--- 276
Query: 83 PSVRPLLHCAPGFCFPGVACIQTES--GARCGPCPAGFTGNGSHCTDVNEC-NAHPCFPR 139
HC+P CF GV C++ G RCGPCP G GNG+HC+D+NEC +A PCFP
Sbjct: 277 -------HCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPG 329
Query: 140 VRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHN-CVPNSVCI 198
CINT PGF CEACP GY G GVG+ +A+A+KQVC DI+EC G + C PNS+C
Sbjct: 330 SSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICT 389
Query: 199 NTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVG 258
NT GSF+CGPC+ GF+G+Q+ GC R C + S CH HA C+ ER+G+ SC C VG
Sbjct: 390 NTVGSFKCGPCRLGFLGNQSQGCL--PARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVG 447
Query: 259 WAGNGILCGRDTDLDGFPDEKLRCPE--RQCRKDNCVTVPNSGQEDVDRDGIGDACDPDA 316
WAGNG +CG DTD+DG+PD+ L C + + C++DNC+ PNSGQED D DG+GD CD DA
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDA 507
Query: 317 DGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDID 376
DGDG+ N +DNC L N DQ+N+D D +GDACDNC + N+DQKDTD +G GDACD+D+D
Sbjct: 508 DGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVD 567
Query: 377 GDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQ 436
GD I N DNCP+VPN Q D D DG+GDACD+CP+ SNP Q D D D VGD CD+++D
Sbjct: 568 GDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDS 627
Query: 437 DGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD----SRDNCRLVPNPGQ 492
DGDGHQD++DNCP +PNS+Q DSD+DG GD CD DDDNDG+PD DNCRLVPNP Q
Sbjct: 628 DGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQ 687
Query: 493 EDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWV 552
+D+D +GVGDVC+DDFD D VVD +DVCPE+AEVTLTDFRA+QTVVLDPEGDAQIDPNWV
Sbjct: 688 KDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWV 747
Query: 553 VLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVV 612
VLNQG EIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGF+F YQDS FYVV
Sbjct: 748 VLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVV 807
Query: 613 MWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPR 672
MWKQ EQTYWQA PFRAVA+PG+QLKAV S +GPGE LRNALWHTG T QVRLLW DPR
Sbjct: 808 MWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPR 867
Query: 673 NVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENI 732
NVGW+DK SYRW L HRPQVGYIRV+ YEGP+LVADS V++DT+MRGGRLGVFCFSQENI
Sbjct: 868 NVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENI 927
Query: 733 IWANLRYRCNDTIPEDYE 750
IW+NL+YRCNDT+PED+E
Sbjct: 928 IWSNLQYRCNDTVPEDFE 945
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 750 bits (1936), Expect = 0.0
Identities = 361/666 (54%), Positives = 434/666 (65%), Gaps = 52/666 (7%)
Query: 87 PLLHCAPGFCFPGVACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHP--CFPR---V 140
P+ C CFPG C G+ CG CP GF GNG+HC D++EC P CF
Sbjct: 549 PVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVP 608
Query: 141 RCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINT 200
RC+NT PGF C CPP Y G GVGL AK KQVC N C+ HNC ++ CI
Sbjct: 609 RCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYL 668
Query: 201 RGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWA 260
G D C+ C G +A
Sbjct: 669 -----------GHFSDPMYKCE------CQTG--------------------------YA 685
Query: 261 GNGILCGRDTDLDGFPDEKLRCPER---QCRKDNCVTVPNSGQEDVDRDGIGDACDPDAD 317
G+G++CG D+DLDG+P+ L C C KDNC +PNSGQED D+DGIGDACD D D
Sbjct: 686 GDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDD 745
Query: 318 GDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDG 377
DGV +EKDNC L+ NP Q + D+D+ GD CDNC N Q DTD +G GDAC DIDG
Sbjct: 746 NDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDG 805
Query: 378 DRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQD 437
D + N+ DNCP V N+DQ+D+DGDG+GD CDNCP NPDQ DVD+D VGD CD+++D D
Sbjct: 806 DDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDID 865
Query: 438 GDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADR 497
DGHQ+++DNCP + N+ Q D D DGQGDACD DDDNDGVPD RDNCRLV NP QED D
Sbjct: 866 DDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDG 925
Query: 498 DGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQG 557
DG GD+C+DDFD D + D DVCPEN ++ TDFR FQ V LDP+G QIDPNWV+ +QG
Sbjct: 926 DGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQG 985
Query: 558 REIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQM 617
+E+VQT NSDPG+AVG+ F VDF GTF+VNT DDDYAGF+FGYQ SS FYVVMWKQ+
Sbjct: 986 KELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQV 1045
Query: 618 EQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWK 677
QTYW+ P RA G+ LK V S+TG GE LRNALWHTG+T QVR LW DPRN+GWK
Sbjct: 1046 TQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWK 1105
Query: 678 DKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANL 737
D +YRW L HRP+ GYIRV +EG +++ADS + D T GGRLG+F FSQE + +++L
Sbjct: 1106 DYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDL 1165
Query: 738 RYRCND 743
+Y C D
Sbjct: 1166 KYECRD 1171
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 747 bits (1929), Expect = 0.0
Identities = 357/671 (53%), Positives = 436/671 (64%), Gaps = 62/671 (9%)
Query: 87 PLLHCAPGFCFPGVACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHP--CF---PRV 140
P+ C CF GV C G+ +CG CP G++GNG CTDV+EC P CF
Sbjct: 547 PIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEH 606
Query: 141 RCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINT 200
RC NT PG+ C CPP ++G G G+ A ANKQVC N C G H+C N+ C N
Sbjct: 607 RCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKC-NY 665
Query: 201 RG-----SFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVC 255
G ++C C+PG+
Sbjct: 666 LGHYSDPMYRC-ECKPGY------------------------------------------ 682
Query: 256 AVGWAGNGILCGRDTDLDGFPDEKLRCPER---QCRKDNCVTVPNSGQEDVDRDGIGDAC 312
AGNGI+CG DTDLDG+P+E L C C+KDNC +PNSGQED D+DGIGDAC
Sbjct: 683 ----AGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDAC 738
Query: 313 DPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACD 372
D D D D +P+++DNCP NP Q + D D GD CDNC N DQ DTD +G GDAC
Sbjct: 739 DDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACA 798
Query: 373 DDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDS 432
DIDGD I N+ DNC V N DQ+D+D DG+GD CDNCP + NPDQ D D D +GD CD+
Sbjct: 799 ADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDN 858
Query: 433 DQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQ 492
+QD D DGHQ++ DNCP VPN+ Q D D DG+GDACD DDDNDG+PD +DNCRLVPNP Q
Sbjct: 859 NQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQ 918
Query: 493 EDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWV 552
+D+D DG GD C+DDFD D V D D+CPEN +++ TDFR FQ + LDP+G +Q DPNWV
Sbjct: 919 KDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWV 978
Query: 553 VLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVV 612
V +QG+E+VQT+N DPGLAVGY FN VDF GTF +NT DDDYAGF+FGYQ SS FYVV
Sbjct: 979 VRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVV 1038
Query: 613 MWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPR 672
MWKQ+ Q+YW NP RA G+ +K V S+TGPGE LRNALWHTG+T QVR LW DPR
Sbjct: 1039 MWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPR 1098
Query: 673 NVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENI 732
++GWKD +YRW L HRP+ G+IRV YEG +++ADS + D T GGRLG+F FSQE +
Sbjct: 1099 HIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMV 1158
Query: 733 IWANLRYRCND 743
+++L+Y C D
Sbjct: 1159 FFSDLKYECRD 1169
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 112 bits (281), Expect = 1e-24
Identities = 87/241 (36%), Positives = 108/241 (44%), Gaps = 42/241 (17%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CTDVNECNAHP--CFPRVRCINTSPG 148
P C G C RC C GF + C DVNEC+ +P C C NT
Sbjct: 1246 PNIC-DGGQCTNIPGEYRC-LCYDGFMASEDMKTCVDVNECDLNPNICLSGT-CENTKGS 1302
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
F C C GYSG K K CTDINECE G HNC ++VC NT GSF+C
Sbjct: 1303 FICH-CDMGYSG-----------KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCS- 1349
Query: 209 CQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGR 268
C PG++GD G + C +G+ C +HADC GS C+C G+ G+G C
Sbjct: 1350 CSPGWIGD---GIKCTDLDECSNGT-HMCSQHADC-KNTMGSYRCLCKEGYTGDGFTC-- 1402
Query: 269 DTDLDGFPDEKLRCPE--RQCRKDNCVTVPNSGQEDVDRDGI----GDACDPDADGDGVP 322
TDLD C E C C+ P + + D + G AC+ D D +P
Sbjct: 1403 -TDLD-------ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLP 1453
Query: 323 N 323
N
Sbjct: 1454 N 1454
Score = 82.0 bits (201), Expect = 2e-15
Identities = 133/534 (24%), Positives = 195/534 (36%), Gaps = 126/534 (23%)
Query: 72 CGMQQ-----SVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSH-- 124
CG Q+ + TGLP PG C GV CI RC CP GF N
Sbjct: 1748 CGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV-CINMVGSFRC-ECPVGFFYNDKLLV 1805
Query: 125 CTDVNECNAHP-CFPRVRCINTSPGFRCEACPPGYS----------------------GP 161
C D++EC P C CINT+ +RC+ C PGY G
Sbjct: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCD-CKPGYRFTSTGQCNDRNECQEIPNICSHGQ 1864
Query: 162 THQGVGLAFA------KAN--KQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
VG + K N + +C DINECE + N C NT GSF C C GF
Sbjct: 1865 CIDTVGSFYCLCHTGFKTNDDQTMCLDINECE---RDACGNGTCRNTIGSFNCR-CNHGF 1920
Query: 214 VGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW--AGNGILCGRDTD 271
+ + C + C G+ + C + C+ GS C C G+ A +G C D
Sbjct: 1921 ILSHNNDCIDVDE--CASGNGNLCR-NGQCI-NTVGSFQCQCNEGYEVAPDGRTC---VD 1973
Query: 272 LDGFPDEKLRCPERQCRKDN----CVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDN 327
++ E +C C+ + C+ P ++ + C+ D D E +
Sbjct: 1974 INECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQN-------EKCE---DIDECVEEPEI 2023
Query: 328 CPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNC 387
C L + E + C S + ++ QD R C +G + +
Sbjct: 2024 CAL----GTCSNTEGSFKCLCPEGFSLSSSGRRC--QDLRMSYCYAKFEGGKCSS----- 2072
Query: 388 PRVPNSDQKDS----DGDGIGDACDNCPQKSN----------------PDQADVDHDFV- 426
P+ N +++ G+G GD C+ CP + + PD + VD D
Sbjct: 2073 PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK 2132
Query: 427 -GDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDAC-DDDDDNDGVPDSRDNC 484
D C Q + DG R CP + G+ C D D+ + G P C
Sbjct: 2133 EPDVCKHGQCINTDG--SYRCECP---------FGYILAGNECVDTDECSVGNPCGNGTC 2181
Query: 485 RLVPNPGQEDADRDGVGDVCQDDFDADKVV--DKIDVCPENAEVTLTDFRAFQT 536
+ V G C++ F+ ++ + I+ C +N L FR T
Sbjct: 2182 KNVIG---------GFECTCEEGFEPGPMMTCEDINECAQNP--LLCAFRCVNT 2224
Score = 73.6 bits (179), Expect = 7e-13
Identities = 62/212 (29%), Positives = 80/212 (37%), Gaps = 50/212 (23%)
Query: 92 APGFCFPGVACIQTESGARCGPCPAGFTGNG---SHCTDVNECNAHPCFPRVR-CINTSP 147
+P C G C+ T C C G+ +C D++EC P R C NT
Sbjct: 1077 SPDLCGRG-QCVNTPGDFEC-KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEG 1134
Query: 148 GFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
+RCE CPPG+ N C DINECE H C PN C+N G +QC
Sbjct: 1135 SYRCE-CPPGHQ-----------LSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCA 1181
Query: 208 PCQPGFVG----------DQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
C PG+ D+ S + FC + +GS C C
Sbjct: 1182 -CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNS---------------EGSYECSCQP 1225
Query: 258 GWA--GNGILCGRDTDLDGFPDEKLRCPERQC 287
G+A + C TD+D D C QC
Sbjct: 1226 GFALMPDQRSC---TDIDECEDNPNICDGGQC 1254
Score = 72.4 bits (176), Expect = 1e-12
Identities = 64/223 (28%), Positives = 92/223 (41%), Gaps = 58/223 (26%)
Query: 68 ECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGN---GSH 124
E D C Q + T S R C G+ G C+ T+ + PC G N G
Sbjct: 2133 EPDVCKHGQCINTD-GSYR--CECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFE 2189
Query: 125 CT--------------DVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAF 170
CT D+NEC +P RC+NT + C+ CP GY
Sbjct: 2190 CTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECK-CPVGY-----------V 2237
Query: 171 AKANKQVCTDINECETGQHNCVPNSV-CINTRGSFQCGPCQPGFVGDQASGCQRRAQRFC 229
+ ++++C D +ECE G+H+C + C N G++ C C PG+ QRR
Sbjct: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMC-ICGPGY--------QRR----- 2283
Query: 230 PDG----SPSECH------EHADCVLERDGSRSCVCAVGWAGN 262
PDG +EC E+ C+ R GS +C C G+ +
Sbjct: 2284 PDGEGCVDENECQTKPGICENGRCLNTR-GSYTCECNDGFTAS 2325
Score = 71.2 bits (173), Expect = 3e-12
Identities = 82/315 (26%), Positives = 115/315 (36%), Gaps = 68/315 (21%)
Query: 69 CDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CT 126
CD + TG + R P C G CI T C C GF N C
Sbjct: 1833 CDCKPGYRFTSTGQCNDRNECQEIPNICSHG-QCIDTVGSFYC-LCHTGFKTNDDQTMCL 1890
Query: 127 DVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECET 186
D+NEC C C NT F C C G F ++ C D++EC +
Sbjct: 1891 DINECERDAC-GNGTCRNTIGSFNCR-CNHG------------FILSHNNDCIDVDECAS 1936
Query: 187 GQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLE 246
G N N CINT GSFQC C G+ PDG C + +C+LE
Sbjct: 1937 GNGNLCRNGQCINTVGSFQC-QCNEGY-------------EVAPDG--RTCVDINECLLE 1980
Query: 247 -----------RDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKD----N 291
DGS C+C G++ C D+D +E C C
Sbjct: 1981 PRKCAPGTCQNLDGSYRCICPPGYSLQNEKC---EDIDECVEEPEICALGTCSNTEGSFK 2037
Query: 292 CV-----TVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRN----TDED 342
C+ ++ +SG+ +D C +G K + P RN ++ +
Sbjct: 2038 CLCPEGFSLSSSGRR--CQDLRMSYCYAKFEGG-----KCSSPKSRNHSKQECCCALKGE 2090
Query: 343 KWGDACDNCRSQKND 357
WGD C+ C ++ ++
Sbjct: 2091 GWGDPCELCPTEPDE 2105
Score = 70.5 bits (171), Expect = 6e-12
Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 18/120 (15%)
Query: 102 CIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C+ C C G+T + G+ C D+NECN P C NT ++C +CP GY
Sbjct: 2418 CVNDRGSYHC-ICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQC-SCPKGY- 2474
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
+ + + C D++EC T QHNC +C+NT G F C C PGF S
Sbjct: 2475 ----------ILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGFTC-KCPPGFTQHHTS 2521
Score = 68.6 bits (166), Expect = 2e-11
Identities = 56/197 (28%), Positives = 77/197 (39%), Gaps = 57/197 (28%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEACPPG 157
C TE +C CP G+ +G C D++EC H C + C+NT GF C+ CPPG
Sbjct: 2459 CKNTEGSYQCS-CPKGYILQEDGRSCKDLDECATKQHNC--QFLCVNTIGGFTCK-CPPG 2514
Query: 158 YSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQ 217
++ + C D NEC + + C +C NT GSF C CQ GF DQ
Sbjct: 2515 FT-------------QHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC-ECQRGFSLDQ 2560
Query: 218 ASG-------------CQRRAQRF-------CPDG-----SPSECHEHADCVLERD---- 248
CQ Q CP G ++C + +C+
Sbjct: 2561 TGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGA 2620
Query: 249 ------GSRSCVCAVGW 259
GS C+C G+
Sbjct: 2621 SCHNTLGSYKCMCPAGF 2637
Score = 64.3 bits (155), Expect = 4e-10
Identities = 54/173 (31%), Positives = 68/173 (39%), Gaps = 34/173 (19%)
Query: 102 CIQTESGARCGPCPAGFTGN-GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSG 160
CI T RC C GF + C DV+EC +PC CIN + C+ C GY
Sbjct: 465 CIPTPGSCRC-ECNKGFQLDLRGECIDVDECEKNPCAGG-ECINNQGSYTCQ-CRAGYQ- 520
Query: 161 PTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF-VGDQAS 219
+ + C DI+EC C N CINT GSF C C GF V
Sbjct: 521 ----------STLTRTECRDIDECLQNGRIC-NNGRCINTDGSFHC-VCNAGFHVTRDGK 568
Query: 220 GCQRRAQRFCPDGSPSECHEHADCV----LERDGSRSCVCAVGW--AGNGILC 266
C+ EC C+ + DGS C+C G+ A +G C
Sbjct: 569 NCE----------DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 63.9 bits (154), Expect = 5e-10
Identities = 40/113 (35%), Positives = 54/113 (47%), Gaps = 18/113 (15%)
Query: 102 CIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
CI T+ C C AGF T +G +C D++EC+ CIN F+C C PG+
Sbjct: 546 CINTDGSFHC-VCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKC-ICKPGFQ 603
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPG 212
++ + C DINECET N C+NT GS++C C PG
Sbjct: 604 -----------LASDGRYCKDINECET--PGICMNGRCVNTDGSYRC-ECFPG 642
Score = 58.9 bits (141), Expect = 2e-08
Identities = 77/308 (25%), Positives = 110/308 (35%), Gaps = 49/308 (15%)
Query: 114 CPAG---FTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAF 170
CP G G D++EC +CINT +RCE CP GY ++
Sbjct: 2111 CPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCE-CPFGYILAGNE------ 2163
Query: 171 AKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCP 230
C D +EC G N N C N G F+C C+ GF C+
Sbjct: 2164 -------CVDTDECSVG--NPCGNGTCKNVIGGFEC-TCEEGFEPGPMMTCE-------- 2205
Query: 231 DGSPSECHEH----ADCVLERDGSRSCVCAVGWA--GNGILCGRDTDLDGFPDEKLRCPE 284
+EC ++ A + GS C C VG+ + +C D D + K C E
Sbjct: 2206 --DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMC---KDEDECEEGKHDCTE 2260
Query: 285 RQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCP-LVRNPDQRNTDEDK 343
+Q N + + G G PD +G NE P + N NT
Sbjct: 2261 KQMECKNLIGT------YMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSY 2314
Query: 344 WGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGI 403
+ D + N D+ D R C ++ + + + N V S+ G G
Sbjct: 2315 TCECNDGFTASPNQDE---CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW 2371
Query: 404 GDACDNCP 411
G C+ CP
Sbjct: 2372 GPHCEICP 2379
Score = 56.2 bits (134), Expect = 1e-07
Identities = 40/115 (34%), Positives = 51/115 (44%), Gaps = 20/115 (17%)
Query: 102 CIQTESGARCGPCPAGFTGN--GSHCTDVNEC-NAHPCFPRVRCINTSPGFRCEACPPGY 158
C G RC CP G+ + + C D NEC +AH C C NT ++C CP G+
Sbjct: 2581 CQNIIGGYRCS-CPQGYLQHYQWNQCVDENECLSAHIC-GGASCHNTLGSYKC-MCPAGF 2637
Query: 159 SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
G C DINEC + Q C + C NT G + CG C PG+
Sbjct: 2638 QYEQFSGG-----------CQDINECGSAQAPC--SYGCSNTEGGYLCG-CPPGY 2678
Score = 54.7 bits (130), Expect = 3e-07
Identities = 82/328 (25%), Positives = 117/328 (35%), Gaps = 86/328 (26%)
Query: 15 ALGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREITFLKNTVMECDACGM 74
AL +SG G + GSD+ L + + + E LR + I N+ E D+ G
Sbjct: 709 ALCSSGPGMTSAGSDINECAL----DPDICPNGICENLRGTYKCIC---NSGYEVDSTG- 760
Query: 75 QQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGS--HCTDVNECN 132
+ V + LL C G C + G+ CP GF C D++EC
Sbjct: 761 KNCVDINECVLNSLL-CDNGQC-------RNTPGSFVCTCPKGFIYKPDLKTCEDIDECE 812
Query: 133 AHPCFPRVRCINTSPGFRCEA-----------------------------CPPGYSGPTH 163
+ PC V C N+ F CE C +G T
Sbjct: 813 SSPCINGV-CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL 871
Query: 164 QG----------------------VGLAFAKANKQVCTDINECETGQHNCVPNSVCINTR 201
+ G +++ C DI+ECE C N +C+NTR
Sbjct: 872 KSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVC-KNGLCVNTR 930
Query: 202 GSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSEC---HEHADCVLERDGSR---SCVC 255
GSF+C C G D A+G R C D C +E +C L G +C C
Sbjct: 931 GSFKC-QCPSGMTLD-ATG------RICLDIRLETCFLRYEDEECTLPIAGRHRMDACCC 982
Query: 256 AVGWAGNGILCGRDTDLDGFPDEKLRCP 283
+VG A C + + P+ + CP
Sbjct: 983 SVGAAWGTEEC-EECPMRNTPEYEELCP 1009
Score = 52.4 bits (124), Expect = 2e-06
Identities = 59/223 (26%), Positives = 82/223 (36%), Gaps = 52/223 (23%)
Query: 96 CFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEA 153
C G+ CI + +C C GF +G +C D+NEC RC+NT +RCE
Sbjct: 582 CLNGM-CINEDGSFKC-ICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCE- 638
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDIN------------ECETGQHNCVPNSVCINTR 201
C PG + VGL + +VC D + +C V S C
Sbjct: 639 CFPGLA------VGL-----DGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAS 687
Query: 202 GSFQCG-PCQPGFVGDQASGCQRRAQRFCPD--GSPSECHEHADCVLERD---------- 248
+ G PCQP + A Q C G S + +C L+ D
Sbjct: 688 TEYAFGEPCQPCPAQNSA-----EYQALCSSGPGMTSAGSDINECALDPDICPNGICENL 742
Query: 249 -GSRSCVCAVGWA--GNGILCGRDTDLDGFPDEKLRCPERQCR 288
G+ C+C G+ G C D++ L C QCR
Sbjct: 743 RGTYKCICNSGYEVDSTGKNC---VDINECVLNSLLCDNGQCR 782
Score = 51.2 bits (121), Expect = 3e-06
Identities = 40/106 (37%), Positives = 47/106 (44%), Gaps = 21/106 (19%)
Query: 113 PCPAGFTGN--GSHCTDVNECNAHPCFPRV-RCINTSPGFRCEACPPGYSGPTHQGVGLA 169
PC GF N C DV+EC A P + CINT F C+ CP G+
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECK-CPAGH----------- 277
Query: 170 FAKANK--QVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
K N+ Q C DI+EC T C C NT S+ C C PGF
Sbjct: 278 --KLNEVSQKCEDIDECSTIPGIC-EGGECTNTVSSYFC-KCPPGF 319
Score = 50.8 bits (120), Expect = 5e-06
Identities = 67/264 (25%), Positives = 95/264 (35%), Gaps = 72/264 (27%)
Query: 91 CAPG--FCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC--NAHPCFPRVRCINTS 146
C+ G C C T RC C G+TG+G CTD++EC N + C +C+N
Sbjct: 1367 CSNGTHMCSQHADCKNTMGSYRC-LCKEGYTGDGFTCTDLDECSENLNLC-GNGQCLNAP 1424
Query: 147 PGFRCEACPPGYS----------------------GPTHQGVGLAFAKANKQV------- 177
G+RCE C G+ G H GL +
Sbjct: 1425 GGYRCE-CDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGG 1483
Query: 178 -CTDINE------CETGQHNCVPNSVCINTRGSFQCGPCQPGF-VGDQASGCQRRAQRFC 229
CTD+NE C +G C+NT GS+ C C P F + GC C
Sbjct: 1484 NCTDVNECLDPTTCISGN--------CVNTPGSYIC-DCPPDFELNPTRVGCVDTRSGNC 1534
Query: 230 -------PDGSPSECHEHADCVLERDGSRSCVCAVG--WAGNGILCGRDTDLDGFPDEKL 280
D + C + + SC C++G W +C + K+
Sbjct: 1535 YLDIRPRGDNGDTACSNEIGVGVSK---ASCCCSLGKAWGTPCEMC----PAVNTSEYKI 1587
Query: 281 RCPERQCRKDNCVTVPNSGQEDVD 304
CP + + N +TV ED+D
Sbjct: 1588 LCPGGEGFRPNPITVI---LEDID 1608
Score = 48.1 bits (113), Expect = 3e-05
Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 16/89 (17%)
Query: 127 DVNECNAHPCFPRV-RCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE 185
D++EC P + +CINT F+C CP GY + + +VC D+NECE
Sbjct: 1606 DIDECQELPGLCQGGKCINTFGSFQCR-CPTGY-----------YLNEDTRVCDDVNECE 1653
Query: 186 TGQHNCVPNSVCINTRGSFQCGPCQPGFV 214
T C P + C NT G++ C C P ++
Sbjct: 1654 T-PGICGPGT-CYNTVGNYTC-ICPPDYM 1679
Score = 46.6 bits (109), Expect = 9e-05
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 6/90 (6%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPG 148
C G +C T +C CPAGF C D+NEC + C NT G
Sbjct: 2611 CLSAHICGGASCHNTLGSYKC-MCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGG 2669
Query: 149 FRCEACPPGY--SGPTHQGVGLAFAKANKQ 176
+ C CPPGY G H G+ + N +
Sbjct: 2670 YLC-GCPPGYFRIGQGHCVSGMGMGRGNPE 2698
Score = 46.2 bits (108), Expect = 1e-04
Identities = 108/479 (22%), Positives = 145/479 (30%), Gaps = 114/479 (23%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CTDVNECNAHPCFPRVRCINTSPGFR 150
PG C G CI T +C CP G+ N C DVNEC C NT +
Sbjct: 1614 PGLC-QGGKCINTFGSFQCR-CPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYT 1671
Query: 151 CEACPPGY-----------------------SGPTHQGVGLAFAKANKQVCTDINECETG 187
C CPP Y T G L F K C N
Sbjct: 1672 C-ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDG-ELLFNMTKKMCCCSYNIGRAW 1729
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLER 247
C + + CG +PGFV D +G C + P C E+ C+
Sbjct: 1730 NKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDE-CRE-IPGVC-ENGVCI-NM 1785
Query: 248 DGSRSCVCAVGWAGNG-ILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRD 306
GS C C VG+ N +L D D C + N + +G D
Sbjct: 1786 VGSFRCECPVGFFYNDKLLVCEDID---------ECQNGPVCQRNAECINTAGSYRCD-- 1834
Query: 307 GIGDACDPD--ADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRS--QKNDDQKDT 362
C P G N+++ C + N D G C + + NDDQ
Sbjct: 1835 -----CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQ--- 1886
Query: 363 DQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDN--CPQKSNPDQAD 420
C D + C R DAC N C
Sbjct: 1887 ------TMCLD----------INECER---------------DACGNGTCRNTIGSFNCR 1915
Query: 421 VDHDFV----GDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDG 476
+H F+ D D D+ G+G+ C S Q C ++ +
Sbjct: 1916 CNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQ-----------CQCNEGYEV 1964
Query: 477 VPDSR-----DNCRLVPN---PGQEDADRDGVGDVCQDDFD-ADKVVDKIDVCPENAEV 526
PD R + C L P PG +C + ++ + ID C E E+
Sbjct: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEI 2023
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/188 (27%), Positives = 71/188 (37%), Gaps = 33/188 (17%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNAHPCFPRVR-------CI 143
PG C G C+ T C C GFT N C D E CF V
Sbjct: 2299 PGICENG-RCLNTRGSYTC-ECNDGFTASPNQDECLDNREGY---CFTEVLQNMCQIGSS 2353
Query: 144 NTSPGFRCEACPPGYSG--PTHQGVGLAFAKANKQVC----------TDINECETGQHNC 191
N +P + E C G G P + A K++C DI+EC+ H+
Sbjct: 2354 NRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV-IHDV 2412
Query: 192 VPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSR 251
N C+N RGS+ C C+ G+ D +G C + +P C+ +GS
Sbjct: 2413 CRNGECVNDRGSYHC-ICKTGYTPD-ITGTSCVDLNEC-NQAPKPCN---FICKNTEGSY 2466
Query: 252 SCVCAVGW 259
C C G+
Sbjct: 2467 QCSCPKGY 2474
Score = 37.7 bits (86), Expect = 0.040
Identities = 34/118 (28%), Positives = 47/118 (39%), Gaps = 14/118 (11%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRC--INTSPG 148
CA + F G C E R GPC FT + + + C + C + + G
Sbjct: 166 CACTYGFTGPQC---ERDYRTGPC---FTVISNQMCQ-GQLSGIVCTKTLCCATVGRAWG 218
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
CE CP P +G C D++EC+ C + CINT GSF+C
Sbjct: 219 HPCEMCP-AQPHPCRRGF---IPNIRTGACQDVDECQAIPGLCQGGN-CINTVGSFEC 271
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 100 bits (248), Expect = 7e-21
Identities = 67/201 (33%), Positives = 87/201 (43%), Gaps = 31/201 (15%)
Query: 102 CIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C TE +C CP GF N GS C DV+EC H P C+N+ F+C CP G+
Sbjct: 701 CENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHH 759
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
H+G CTD++EC +G C P+ C NT GSF+C C PG+
Sbjct: 760 --LHRG-----------RCTDVDECSSGAPPCGPHGHCTNTEGSFRCS-CAPGYRAPSGR 805
Query: 220 GCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW--AGNGILCGRDTDLDGFPD 277
C +G C H +C L DGS +C CA G+ G C D+D +
Sbjct: 806 PGPCADVNECLEG--DFCFPHGEC-LNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 859
Query: 278 EKLRCPERQCRKDNCVTVPNS 298
E L C+ C S
Sbjct: 860 EDL------CQSGICTNTDGS 874
Score = 100 bits (248), Expect = 7e-21
Identities = 78/251 (31%), Positives = 99/251 (39%), Gaps = 52/251 (20%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECN--AHPCFPRVRCINTSPG 148
C PG C+ + +C CP+G + CTDV+EC+ A PC P C NT
Sbjct: 731 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 790
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
FRC +C PGY P+ C D+NEC G C P+ C+NT GSF C
Sbjct: 791 FRC-SCAPGYRAPS----------GRPGPCADVNECLEGDF-CFPHGECLNTDGSFAC-T 837
Query: 209 CQPGF-VGDQASGCQRRAQRFCPDGSPSECHEHADC----VLERDGSRSCVCAVGW-AGN 262
C PG+ G + + C EC E C DGS C+C G AG
Sbjct: 838 CAPGYRPGPRGASCL----------DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 887
Query: 263 GILCGRDTDLDGFPDEKLRCPER---QCRKDNCVTVPNSGQEDVDRDGIGDACDP--DAD 317
+ D D C ER C C P S + D CDP A
Sbjct: 888 DLASCLDVD---------ECRERGPALCGSQRCENSPGSYRCVRD-------CDPGYHAG 931
Query: 318 GDGVPNEKDNC 328
+G ++ D C
Sbjct: 932 PEGTCDDVDEC 942
Score = 71.2 bits (173), Expect = 3e-12
Identities = 63/220 (28%), Positives = 84/220 (38%), Gaps = 47/220 (21%)
Query: 83 PSVRP-----LLHCAPG-FCFPGVACIQTESGARCGPCPAGFTG-NGSHCTDVNECNAHP 135
PS RP + C G FCFP C+ T+ C P G G+ C DV+EC+
Sbjct: 802 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 861
Query: 136 CFPRVRCINTSPGFRCEACPPGY-SGPT-----------HQGVGLA-------------- 169
C NT F C CPPG+ +GP +G L
Sbjct: 862 LCQSGICTNTDGSFEC-ICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 920
Query: 170 -------FAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP-CQPGFVGDQASGC 221
+ + C D++EC+ C NT GS++C P C PG+ GC
Sbjct: 921 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGC 980
Query: 222 QRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAG 261
Q + C + S C HA C GS C+C G+ G
Sbjct: 981 QDVDE--C--RNRSFCGAHAVC-QNLPGSFQCLCDQGYEG 1015
Score = 66.6 bits (161), Expect = 8e-11
Identities = 63/185 (34%), Positives = 77/185 (41%), Gaps = 31/185 (16%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNA--HPCFPRVRCINTSPG 148
P C PG CI SG C C +GF + G+ C DV+EC PC P RC N+
Sbjct: 486 PQVCGPG-RCISRPSGYTCA-CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS 542
Query: 149 FRCEACPPGY-SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
FRC C PG+ +GP C D++EC C C NT GSF C
Sbjct: 543 FRC-VCGPGFRAGP------------RAAECLDVDECHRVPPPC-DLGRCENTPGSFLC- 587
Query: 208 PCQPGF-VGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C G+ + CQ + C SP C A GS CVC G+ G+ C
Sbjct: 588 VCPAGYQAAPHGASCQDVDE--CTQ-SPGLCGRGA--CKNLPGSFRCVCPAGFRGSA--C 640
Query: 267 GRDTD 271
D D
Sbjct: 641 EEDVD 645
Score = 63.5 bits (153), Expect = 7e-10
Identities = 104/417 (24%), Positives = 138/417 (33%), Gaps = 75/417 (17%)
Query: 90 HCAPGFCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNAHP-CFPRVRCINTS 146
H P C G C T C CPAG+ +G+ C DV+EC P R C N
Sbjct: 567 HRVPPPCDLG-RCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLP 624
Query: 147 PGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
FRC CP G+ G + D++EC C P C NT GSF C
Sbjct: 625 GSFRC-VCPAGFRGSACE--------------EDVDECAQEPPPCGPGR-CDNTAGSFHC 668
Query: 207 GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C GF + G + C P + + +GS CVC +G+ N
Sbjct: 669 A-CPAGF-RSRGPGAPCQDVDECARSPPPCTYGRCE---NTEGSFQCVCPMGFQPN--TA 721
Query: 267 GRDTDLDGFPDEKLRCPERQCRKD----NCVTVPNSGQEDVDRDGIGDACDPDADGDGVP 322
G + + + L CP ++C C T P+ R D C A G
Sbjct: 722 GSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPH 781
Query: 323 NEKDN---------CPLVRNPDQR-----NTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
N P R P R + +E GD C N D G
Sbjct: 782 GHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD---------G 832
Query: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDN-----CP--QKSNPDQADV 421
G R + +C V ++D GI D CP ++ PD A
Sbjct: 833 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLA-- 890
Query: 422 DHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQ--EDSD---HDGQGDACDDDDD 473
D D+ ++ C P S + D D H G CDD D+
Sbjct: 891 ------SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 941
Score = 53.5 bits (127), Expect = 7e-07
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 16/108 (14%)
Query: 102 CIQTESGARCGP-CPAGFTGN-GSHCTDVNEC-NAHPCFPRVRCINTSPGFRCEACPPGY 158
C T RC P C G+ G C DV+EC N C C N F+C C GY
Sbjct: 955 CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC-LCDQGY 1013
Query: 159 SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
G + + C D+NECET Q C ++C N GSF C
Sbjct: 1014 EGAR-----------DGRHCVDVNECETLQGVC-GAALCENVEGSFLC 1049
Score = 47.4 bits (111), Expect = 5e-05
Identities = 57/192 (29%), Positives = 79/192 (41%), Gaps = 40/192 (20%)
Query: 102 CIQTESGARCGPCPAGF-----TGNGSHCTDVNECNA---HPCFPRVRCINTSPGFRCEA 153
C TE+ CP G +G+ S DV+EC C V C+NT+PG+ C
Sbjct: 1156 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC-Y 1213
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C GY + + C D +EC + C C+NT GS+ C C+P
Sbjct: 1214 CSNGY-----------YYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC-TCEPPL 1260
Query: 214 VGDQASGCQRRA---QRFCPDGSPSECHEH--ADCV-----LERDGS-RSCVCAVG--WA 260
V D G QRR + D + C + AD V L+R + C C G W
Sbjct: 1261 VLD---GSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWG 1317
Query: 261 GNGILC-GRDTD 271
+ LC +D+D
Sbjct: 1318 MDCALCPAQDSD 1329
Score = 47.4 bits (111), Expect = 5e-05
Identities = 36/102 (35%), Positives = 44/102 (43%), Gaps = 12/102 (11%)
Query: 115 PAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKAN 174
P G + GS E A C C N RC P G++ G L +
Sbjct: 1449 PEGGSYAGSLAEPYEELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRLDMTR-- 1502
Query: 175 KQVCTDINEC---ETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C DINEC E CV N+ C+NT GSF+C C+PGF
Sbjct: 1503 -MACVDINECDEAEAASPLCV-NARCLNTDGSFRC-ICRPGF 1541
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 16/72 (22%)
Query: 107 SGARCGPCPAGFTGN----------GSHCTDVNECN----AHPCFPRVRCINTSPGFRCE 152
+ RC P GFT C D+NEC+ A P RC+NT FRC
Sbjct: 1477 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC- 1535
Query: 153 ACPPGYSGPTHQ 164
C PG++ PTHQ
Sbjct: 1536 ICRPGFA-PTHQ 1546
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 112 GPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGY 158
GPCP GF C DV+EC C NT G+ C CP G+
Sbjct: 275 GPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTC-VCPDGF 320
Score = 33.5 bits (75), Expect = 0.75
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 178 CTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQA-SGC 221
C D++EC TG + C NTRG + C C GF+ D + S C
Sbjct: 288 CEDVDECATGGR--CQHGECANTRGGYTC-VCPDGFLLDSSRSSC 329
Score = 32.7 bits (73), Expect = 1.3
Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 56/224 (25%)
Query: 148 GFRCEACP----PGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGS 203
G R + CP Y G G + + D++EC+ + + VC+NT
Sbjct: 1150 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1209
Query: 204 FQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLER---DGSRSCVCAVGWA 260
+ C C G+ QR EC ++ +C E +G R CV VG
Sbjct: 1210 YSCY-CSNGYY--------YHTQRL-------ECIDNDECADEEPACEGGR-CVNTVG-- 1250
Query: 261 GNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDG 320
C LDG +R+C V N Q D G+ C + D
Sbjct: 1251 SYHCTCEPPLVLDG--------SQRRC-------VSNESQSLDDNLGV---CWQEVGADL 1292
Query: 321 VPNEKDNCPLVRNPDQRNTDE------DKWGDACDNCRSQKNDD 358
V C R Q E + WG C C +Q +DD
Sbjct: 1293 V------CSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDD 1330
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/64 (32%), Positives = 24/64 (37%), Gaps = 5/64 (7%)
Query: 95 FCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNA-HPCFPRVRCINTSPGFRC 151
FC C +C C G+ G +G HC DVNEC C N F C
Sbjct: 991 FCGAHAVCQNLPGSFQC-LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1049
Query: 152 EACP 155
CP
Sbjct: 1050 -VCP 1052
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 100 bits (248), Expect = 7e-21
Identities = 67/201 (33%), Positives = 87/201 (43%), Gaps = 31/201 (15%)
Query: 102 CIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C TE +C CP GF N GS C DV+EC H P C+N+ F+C CP G+
Sbjct: 731 CENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHH 789
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
H+G CTD++EC +G C P+ C NT GSF+C C PG+
Sbjct: 790 --LHRG-----------RCTDVDECSSGAPPCGPHGHCTNTEGSFRCS-CAPGYRAPSGR 835
Query: 220 GCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW--AGNGILCGRDTDLDGFPD 277
C +G C H +C L DGS +C CA G+ G C D+D +
Sbjct: 836 PGPCADVNECLEG--DFCFPHGEC-LNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 889
Query: 278 EKLRCPERQCRKDNCVTVPNS 298
E L C+ C S
Sbjct: 890 EDL------CQSGICTNTDGS 904
Score = 100 bits (248), Expect = 7e-21
Identities = 78/251 (31%), Positives = 99/251 (39%), Gaps = 52/251 (20%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECN--AHPCFPRVRCINTSPG 148
C PG C+ + +C CP+G + CTDV+EC+ A PC P C NT
Sbjct: 761 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 820
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
FRC +C PGY P+ C D+NEC G C P+ C+NT GSF C
Sbjct: 821 FRC-SCAPGYRAPS----------GRPGPCADVNECLEGDF-CFPHGECLNTDGSFAC-T 867
Query: 209 CQPGF-VGDQASGCQRRAQRFCPDGSPSECHEHADC----VLERDGSRSCVCAVGW-AGN 262
C PG+ G + + C EC E C DGS C+C G AG
Sbjct: 868 CAPGYRPGPRGASCL----------DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 917
Query: 263 GILCGRDTDLDGFPDEKLRCPER---QCRKDNCVTVPNSGQEDVDRDGIGDACDP--DAD 317
+ D D C ER C C P S + D CDP A
Sbjct: 918 DLASCLDVD---------ECRERGPALCGSQRCENSPGSYRCVRD-------CDPGYHAG 961
Query: 318 GDGVPNEKDNC 328
+G ++ D C
Sbjct: 962 PEGTCDDVDEC 972
Score = 71.2 bits (173), Expect = 3e-12
Identities = 63/220 (28%), Positives = 84/220 (38%), Gaps = 47/220 (21%)
Query: 83 PSVRP-----LLHCAPG-FCFPGVACIQTESGARCGPCPAGFTG-NGSHCTDVNECNAHP 135
PS RP + C G FCFP C+ T+ C P G G+ C DV+EC+
Sbjct: 832 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 891
Query: 136 CFPRVRCINTSPGFRCEACPPGY-SGPT-----------HQGVGLA-------------- 169
C NT F C CPPG+ +GP +G L
Sbjct: 892 LCQSGICTNTDGSFEC-ICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 950
Query: 170 -------FAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP-CQPGFVGDQASGC 221
+ + C D++EC+ C NT GS++C P C PG+ GC
Sbjct: 951 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGC 1010
Query: 222 QRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAG 261
Q + C + S C HA C GS C+C G+ G
Sbjct: 1011 QDVDE--C--RNRSFCGAHAVC-QNLPGSFQCLCDQGYEG 1045
Score = 66.6 bits (161), Expect = 8e-11
Identities = 63/185 (34%), Positives = 77/185 (41%), Gaps = 31/185 (16%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNA--HPCFPRVRCINTSPG 148
P C PG CI SG C C +GF + G+ C DV+EC PC P RC N+
Sbjct: 516 PQVCGPG-RCISRPSGYTCA-CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS 572
Query: 149 FRCEACPPGY-SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
FRC C PG+ +GP C D++EC C C NT GSF C
Sbjct: 573 FRC-VCGPGFRAGP------------RAAECLDVDECHRVPPPC-DLGRCENTPGSFLC- 617
Query: 208 PCQPGF-VGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C G+ + CQ + C SP C A GS CVC G+ G+ C
Sbjct: 618 VCPAGYQAAPHGASCQDVDE--CTQ-SPGLCGRGA--CKNLPGSFRCVCPAGFRGSA--C 670
Query: 267 GRDTD 271
D D
Sbjct: 671 EEDVD 675
Score = 63.5 bits (153), Expect = 7e-10
Identities = 104/417 (24%), Positives = 138/417 (33%), Gaps = 75/417 (17%)
Query: 90 HCAPGFCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNAHP-CFPRVRCINTS 146
H P C G C T C CPAG+ +G+ C DV+EC P R C N
Sbjct: 597 HRVPPPCDLG-RCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLP 654
Query: 147 PGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
FRC CP G+ G + D++EC C P C NT GSF C
Sbjct: 655 GSFRC-VCPAGFRGSACE--------------EDVDECAQEPPPCGPGR-CDNTAGSFHC 698
Query: 207 GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C GF + G + C P + + +GS CVC +G+ N
Sbjct: 699 A-CPAGF-RSRGPGAPCQDVDECARSPPPCTYGRCE---NTEGSFQCVCPMGFQPN--TA 751
Query: 267 GRDTDLDGFPDEKLRCPERQCRKD----NCVTVPNSGQEDVDRDGIGDACDPDADGDGVP 322
G + + + L CP ++C C T P+ R D C A G
Sbjct: 752 GSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPH 811
Query: 323 NEKDN---------CPLVRNPDQR-----NTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
N P R P R + +E GD C N D G
Sbjct: 812 GHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD---------G 862
Query: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDN-----CP--QKSNPDQADV 421
G R + +C V ++D GI D CP ++ PD A
Sbjct: 863 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLA-- 920
Query: 422 DHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQ--EDSD---HDGQGDACDDDDD 473
D D+ ++ C P S + D D H G CDD D+
Sbjct: 921 ------SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 971
Score = 53.5 bits (127), Expect = 7e-07
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 16/108 (14%)
Query: 102 CIQTESGARCGP-CPAGFTGN-GSHCTDVNEC-NAHPCFPRVRCINTSPGFRCEACPPGY 158
C T RC P C G+ G C DV+EC N C C N F+C C GY
Sbjct: 985 CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC-LCDQGY 1043
Query: 159 SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
G + + C D+NECET Q C ++C N GSF C
Sbjct: 1044 EGAR-----------DGRHCVDVNECETLQGVC-GAALCENVEGSFLC 1079
Score = 47.4 bits (111), Expect = 5e-05
Identities = 57/192 (29%), Positives = 79/192 (41%), Gaps = 40/192 (20%)
Query: 102 CIQTESGARCGPCPAGF-----TGNGSHCTDVNECNA---HPCFPRVRCINTSPGFRCEA 153
C TE+ CP G +G+ S DV+EC C V C+NT+PG+ C
Sbjct: 1186 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC-Y 1243
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C GY + + C D +EC + C C+NT GS+ C C+P
Sbjct: 1244 CSNGY-----------YYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC-TCEPPL 1290
Query: 214 VGDQASGCQRRA---QRFCPDGSPSECHEH--ADCV-----LERDGS-RSCVCAVG--WA 260
V D G QRR + D + C + AD V L+R + C C G W
Sbjct: 1291 VLD---GSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWG 1347
Query: 261 GNGILC-GRDTD 271
+ LC +D+D
Sbjct: 1348 MDCALCPAQDSD 1359
Score = 47.4 bits (111), Expect = 5e-05
Identities = 36/102 (35%), Positives = 44/102 (43%), Gaps = 12/102 (11%)
Query: 115 PAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKAN 174
P G + GS E A C C N RC P G++ G L +
Sbjct: 1479 PEGGSYAGSLAEPYEELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRLDMTR-- 1532
Query: 175 KQVCTDINEC---ETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C DINEC E CV N+ C+NT GSF+C C+PGF
Sbjct: 1533 -MACVDINECDEAEAASPLCV-NARCLNTDGSFRC-ICRPGF 1571
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 16/72 (22%)
Query: 107 SGARCGPCPAGFTGN----------GSHCTDVNECN----AHPCFPRVRCINTSPGFRCE 152
+ RC P GFT C D+NEC+ A P RC+NT FRC
Sbjct: 1507 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC- 1565
Query: 153 ACPPGYSGPTHQ 164
C PG++ PTHQ
Sbjct: 1566 ICRPGFA-PTHQ 1576
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 112 GPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGY 158
GPCP GF C DV+EC C NT G+ C CP G+
Sbjct: 305 GPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTC-VCPDGF 350
Score = 33.5 bits (75), Expect = 0.75
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 178 CTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQA-SGC 221
C D++EC TG + C NTRG + C C GF+ D + S C
Sbjct: 318 CEDVDECATGGR--CQHGECANTRGGYTC-VCPDGFLLDSSRSSC 359
Score = 32.7 bits (73), Expect = 1.3
Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 56/224 (25%)
Query: 148 GFRCEACP----PGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGS 203
G R + CP Y G G + + D++EC+ + + VC+NT
Sbjct: 1180 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1239
Query: 204 FQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLER---DGSRSCVCAVGWA 260
+ C C G+ QR EC ++ +C E +G R CV VG
Sbjct: 1240 YSCY-CSNGYY--------YHTQRL-------ECIDNDECADEEPACEGGR-CVNTVG-- 1280
Query: 261 GNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDG 320
C LDG +R+C V N Q D G+ C + D
Sbjct: 1281 SYHCTCEPPLVLDG--------SQRRC-------VSNESQSLDDNLGV---CWQEVGADL 1322
Query: 321 VPNEKDNCPLVRNPDQRNTDE------DKWGDACDNCRSQKNDD 358
V C R Q E + WG C C +Q +DD
Sbjct: 1323 V------CSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDD 1360
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/64 (32%), Positives = 24/64 (37%), Gaps = 5/64 (7%)
Query: 95 FCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNA-HPCFPRVRCINTSPGFRC 151
FC C +C C G+ G +G HC DVNEC C N F C
Sbjct: 1021 FCGAHAVCQNLPGSFQC-LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1079
Query: 152 EACP 155
CP
Sbjct: 1080 -VCP 1082
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 100 bits (248), Expect = 7e-21
Identities = 67/201 (33%), Positives = 87/201 (43%), Gaps = 31/201 (15%)
Query: 102 CIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C TE +C CP GF N GS C DV+EC H P C+N+ F+C CP G+
Sbjct: 768 CENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHH 826
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
H+G CTD++EC +G C P+ C NT GSF+C C PG+
Sbjct: 827 --LHRG-----------RCTDVDECSSGAPPCGPHGHCTNTEGSFRCS-CAPGYRAPSGR 872
Query: 220 GCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW--AGNGILCGRDTDLDGFPD 277
C +G C H +C L DGS +C CA G+ G C D+D +
Sbjct: 873 PGPCADVNECLEG--DFCFPHGEC-LNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 926
Query: 278 EKLRCPERQCRKDNCVTVPNS 298
E L C+ C S
Sbjct: 927 EDL------CQSGICTNTDGS 941
Score = 100 bits (248), Expect = 7e-21
Identities = 78/251 (31%), Positives = 99/251 (39%), Gaps = 52/251 (20%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECN--AHPCFPRVRCINTSPG 148
C PG C+ + +C CP+G + CTDV+EC+ A PC P C NT
Sbjct: 798 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 857
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
FRC +C PGY P+ C D+NEC G C P+ C+NT GSF C
Sbjct: 858 FRC-SCAPGYRAPS----------GRPGPCADVNECLEGDF-CFPHGECLNTDGSFAC-T 904
Query: 209 CQPGF-VGDQASGCQRRAQRFCPDGSPSECHEHADC----VLERDGSRSCVCAVGW-AGN 262
C PG+ G + + C EC E C DGS C+C G AG
Sbjct: 905 CAPGYRPGPRGASCL----------DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 954
Query: 263 GILCGRDTDLDGFPDEKLRCPER---QCRKDNCVTVPNSGQEDVDRDGIGDACDP--DAD 317
+ D D C ER C C P S + D CDP A
Sbjct: 955 DLASCLDVD---------ECRERGPALCGSQRCENSPGSYRCVRD-------CDPGYHAG 998
Query: 318 GDGVPNEKDNC 328
+G ++ D C
Sbjct: 999 PEGTCDDVDEC 1009
Score = 71.2 bits (173), Expect = 3e-12
Identities = 63/220 (28%), Positives = 84/220 (38%), Gaps = 47/220 (21%)
Query: 83 PSVRP-----LLHCAPG-FCFPGVACIQTESGARCGPCPAGFTG-NGSHCTDVNECNAHP 135
PS RP + C G FCFP C+ T+ C P G G+ C DV+EC+
Sbjct: 869 PSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED 928
Query: 136 CFPRVRCINTSPGFRCEACPPGY-SGPT-----------HQGVGLA-------------- 169
C NT F C CPPG+ +GP +G L
Sbjct: 929 LCQSGICTNTDGSFEC-ICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 987
Query: 170 -------FAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP-CQPGFVGDQASGC 221
+ + C D++EC+ C NT GS++C P C PG+ GC
Sbjct: 988 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGC 1047
Query: 222 QRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAG 261
Q + C + S C HA C GS C+C G+ G
Sbjct: 1048 QDVDE--C--RNRSFCGAHAVC-QNLPGSFQCLCDQGYEG 1082
Score = 66.6 bits (161), Expect = 8e-11
Identities = 63/185 (34%), Positives = 77/185 (41%), Gaps = 31/185 (16%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNA--HPCFPRVRCINTSPG 148
P C PG CI SG C C +GF + G+ C DV+EC PC P RC N+
Sbjct: 553 PQVCGPG-RCISRPSGYTCA-CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGS 609
Query: 149 FRCEACPPGY-SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
FRC C PG+ +GP C D++EC C C NT GSF C
Sbjct: 610 FRC-VCGPGFRAGP------------RAAECLDVDECHRVPPPC-DLGRCENTPGSFLC- 654
Query: 208 PCQPGF-VGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C G+ + CQ + C SP C A GS CVC G+ G+ C
Sbjct: 655 VCPAGYQAAPHGASCQDVDE--CTQ-SPGLCGRGA--CKNLPGSFRCVCPAGFRGSA--C 707
Query: 267 GRDTD 271
D D
Sbjct: 708 EEDVD 712
Score = 63.5 bits (153), Expect = 7e-10
Identities = 104/417 (24%), Positives = 138/417 (33%), Gaps = 75/417 (17%)
Query: 90 HCAPGFCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNAHP-CFPRVRCINTS 146
H P C G C T C CPAG+ +G+ C DV+EC P R C N
Sbjct: 634 HRVPPPCDLG-RCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLP 691
Query: 147 PGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
FRC CP G+ G + D++EC C P C NT GSF C
Sbjct: 692 GSFRC-VCPAGFRGSACE--------------EDVDECAQEPPPCGPGR-CDNTAGSFHC 735
Query: 207 GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C GF + G + C P + + +GS CVC +G+ N
Sbjct: 736 A-CPAGF-RSRGPGAPCQDVDECARSPPPCTYGRCE---NTEGSFQCVCPMGFQPN--TA 788
Query: 267 GRDTDLDGFPDEKLRCPERQCRKD----NCVTVPNSGQEDVDRDGIGDACDPDADGDGVP 322
G + + + L CP ++C C T P+ R D C A G
Sbjct: 789 GSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPH 848
Query: 323 NEKDN---------CPLVRNPDQR-----NTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
N P R P R + +E GD C N D G
Sbjct: 849 GHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD---------G 899
Query: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDN-----CP--QKSNPDQADV 421
G R + +C V ++D GI D CP ++ PD A
Sbjct: 900 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLA-- 957
Query: 422 DHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQ--EDSD---HDGQGDACDDDDD 473
D D+ ++ C P S + D D H G CDD D+
Sbjct: 958 ------SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 1008
Score = 53.5 bits (127), Expect = 7e-07
Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 16/108 (14%)
Query: 102 CIQTESGARCGP-CPAGFTGN-GSHCTDVNEC-NAHPCFPRVRCINTSPGFRCEACPPGY 158
C T RC P C G+ G C DV+EC N C C N F+C C GY
Sbjct: 1022 CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC-LCDQGY 1080
Query: 159 SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
G + + C D+NECET Q C ++C N GSF C
Sbjct: 1081 EGAR-----------DGRHCVDVNECETLQGVC-GAALCENVEGSFLC 1116
Score = 47.4 bits (111), Expect = 5e-05
Identities = 57/192 (29%), Positives = 79/192 (41%), Gaps = 40/192 (20%)
Query: 102 CIQTESGARCGPCPAGF-----TGNGSHCTDVNECNA---HPCFPRVRCINTSPGFRCEA 153
C TE+ CP G +G+ S DV+EC C V C+NT+PG+ C
Sbjct: 1223 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC-Y 1280
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C GY + + C D +EC + C C+NT GS+ C C+P
Sbjct: 1281 CSNGY-----------YYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC-TCEPPL 1327
Query: 214 VGDQASGCQRRA---QRFCPDGSPSECHEH--ADCV-----LERDGS-RSCVCAVG--WA 260
V D G QRR + D + C + AD V L+R + C C G W
Sbjct: 1328 VLD---GSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWG 1384
Query: 261 GNGILC-GRDTD 271
+ LC +D+D
Sbjct: 1385 MDCALCPAQDSD 1396
Score = 47.4 bits (111), Expect = 5e-05
Identities = 36/102 (35%), Positives = 44/102 (43%), Gaps = 12/102 (11%)
Query: 115 PAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKAN 174
P G + GS E A C C N RC P G++ G L +
Sbjct: 1516 PEGGSYAGSLAEPYEELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRLDMTR-- 1569
Query: 175 KQVCTDINEC---ETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C DINEC E CV N+ C+NT GSF+C C+PGF
Sbjct: 1570 -MACVDINECDEAEAASPLCV-NARCLNTDGSFRC-ICRPGF 1608
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 16/72 (22%)
Query: 107 SGARCGPCPAGFTGN----------GSHCTDVNECN----AHPCFPRVRCINTSPGFRCE 152
+ RC P GFT C D+NEC+ A P RC+NT FRC
Sbjct: 1544 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC- 1602
Query: 153 ACPPGYSGPTHQ 164
C PG++ PTHQ
Sbjct: 1603 ICRPGFA-PTHQ 1613
Score = 42.0 bits (97), Expect = 0.002
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 112 GPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGY 158
GPCP GF C DV+EC C NT G+ C CP G+
Sbjct: 342 GPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTC-VCPDGF 387
Score = 33.5 bits (75), Expect = 0.75
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 4/45 (8%)
Query: 178 CTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQA-SGC 221
C D++EC TG + C NTRG + C C GF+ D + S C
Sbjct: 355 CEDVDECATGGR--CQHGECANTRGGYTC-VCPDGFLLDSSRSSC 396
Score = 32.7 bits (73), Expect = 1.3
Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 56/224 (25%)
Query: 148 GFRCEACP----PGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGS 203
G R + CP Y G G + + D++EC+ + + VC+NT
Sbjct: 1217 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1276
Query: 204 FQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLER---DGSRSCVCAVGWA 260
+ C C G+ QR EC ++ +C E +G R CV VG
Sbjct: 1277 YSCY-CSNGYY--------YHTQRL-------ECIDNDECADEEPACEGGR-CVNTVG-- 1317
Query: 261 GNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDG 320
C LDG +R+C V N Q D G+ C + D
Sbjct: 1318 SYHCTCEPPLVLDG--------SQRRC-------VSNESQSLDDNLGV---CWQEVGADL 1359
Query: 321 VPNEKDNCPLVRNPDQRNTDE------DKWGDACDNCRSQKNDD 358
V C R Q E + WG C C +Q +DD
Sbjct: 1360 V------CSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDD 1397
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/64 (32%), Positives = 24/64 (37%), Gaps = 5/64 (7%)
Query: 95 FCFPGVACIQTESGARCGPCPAGFTG--NGSHCTDVNECNA-HPCFPRVRCINTSPGFRC 151
FC C +C C G+ G +G HC DVNEC C N F C
Sbjct: 1058 FCGAHAVCQNLPGSFQC-LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1116
Query: 152 EACP 155
CP
Sbjct: 1117 -VCP 1119
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 94.7 bits (234), Expect = 3e-19
Identities = 65/222 (29%), Positives = 89/222 (40%), Gaps = 37/222 (16%)
Query: 50 ELLRQQVREITFLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGA 109
+L+R+Q E + CDA M R PG C V C T+
Sbjct: 232 DLMREQAGEPKYS----CVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSF 287
Query: 110 RCGPCPAGFTGNGSHCTDVNECNAH----PCFPRVRCINTSPGFRCEACPPGYSGPTHQG 165
CG CP G+ GNG C D+NEC + P V C+NT C+ACPPGY G
Sbjct: 288 YCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQG----- 342
Query: 166 VGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD--QASGCQR 223
+ +VCT + C C P++ C +T GS C PG+ G+ +GC +
Sbjct: 343 --------DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQ 394
Query: 224 RAQRFCPDGSPSECHEH----ADCVLERDGSRSCVCAVGWAG 261
+ + C H C+ + C C GW G
Sbjct: 395 LS---------NICLSHPCLNGQCI-DTVSGYFCKCDSGWTG 426
Score = 86.7 bits (213), Expect = 7e-17
Identities = 57/157 (36%), Positives = 66/157 (42%), Gaps = 24/157 (15%)
Query: 114 CPAG--FTGNGSHCT-DVNECNAHP--CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGL 168
C AG F+ N CT D +EC+ P C V+C NT F C ACP G+ G
Sbjct: 247 CDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQG-------- 298
Query: 169 AFAKANKQVCTDINECETGQHNC--VPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQ 226
N +C DINECE C P C+NT GS C C PG+ GD G
Sbjct: 299 -----NGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGD---GRVCTLT 350
Query: 227 RFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNG 263
C S CH A C C C G+ GNG
Sbjct: 351 DIC-SVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNG 386
Score = 53.9 bits (128), Expect = 5e-07
Identities = 63/242 (26%), Positives = 89/242 (36%), Gaps = 68/242 (28%)
Query: 73 GMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCT-DVNEC 131
G+QQ+V + S P C G C+ C CP + G C+ DVNEC
Sbjct: 126 GLQQTVDKKVCSSNP--------CQNGGTCLNLHDSFFC-ICPPQW--KGPLCSADVNEC 174
Query: 132 NAHP-----CFPRVRCINTSPGFRCEACPPGYSGPTHQGV-----GLAFAKANKQVCTDI 181
+ C C+NT + C CPP GP G + A+ +C D+
Sbjct: 175 EIYSGTPLSCQNGGTCVNTMGSYSCH-CPPETYGPQCASKYDDCEGGSVARCVHGICEDL 233
Query: 182 NECETGQ--HNCV--------PNSV---------------------CINTRGSFQCGPCQ 210
+ G+ ++CV PNS C NT+GSF CG C
Sbjct: 234 MREQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACP 293
Query: 211 PGFVG-----DQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSC-VCAVGWAGNGI 264
G+ G + + C+ C P EC + GS C C G+ G+G
Sbjct: 294 TGWQGNGYICEDINECEIN-NGGCSVAPPVEC-------VNTPGSSHCQACPPGYQGDGR 345
Query: 265 LC 266
+C
Sbjct: 346 VC 347
Score = 53.9 bits (128), Expect = 5e-07
Identities = 62/243 (25%), Positives = 81/243 (33%), Gaps = 79/243 (32%)
Query: 127 DVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCT-DINECE 185
D C+++PC C+N F C CPP + GP +C+ D+NECE
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFC-ICPPQWKGP---------------LCSADVNECE 175
Query: 186 TGQH---NCVPNSVCINTRGSFQCGPCQPGFVGDQASG----CQ-----RRAQRFCPD-- 231
+C C+NT GS+ C C P G Q + C+ R C D
Sbjct: 176 IYSGTPLSCQNGGTCVNTMGSYSCH-CPPETYGPQCASKYDDCEGGSVARCVHGICEDLM 234
Query: 232 ----GSPS-ECHEHAD---------CVLERD-------------------GSRSC-VCAV 257
G P C A C L+RD GS C C
Sbjct: 235 REQAGEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPT 294
Query: 258 GWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDAD 317
GW GNG +C D++ E + C P + AC P
Sbjct: 295 GWQGNGYIC---EDIN----------ECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQ 341
Query: 318 GDG 320
GDG
Sbjct: 342 GDG 344
Score = 40.8 bits (94), Expect = 0.005
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 14/89 (15%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTD-VNECNAHPCFPRVRCINTSPGF 149
C C G CI T SG C C +G+TG +CT+ +NEC ++PC C++ F
Sbjct: 399 CLSHPCLNG-QCIDTVSGYFC-KCDSGWTG--VNCTENINECLSNPCLNGGTCVDGVDSF 454
Query: 150 RCEACPPGYSGPTHQGVGLAFAKANKQVC 178
CE C ++G A + +QVC
Sbjct: 455 SCE-CTRLWTG--------ALCQVPQQVC 474
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 89.7 bits (221), Expect = 9e-18
Identities = 65/182 (35%), Positives = 80/182 (43%), Gaps = 25/182 (13%)
Query: 96 CFPGVACIQTESGARCGP-------CPAGFTGNGSHCTDVNECNAHP--CFPRVRCINTS 146
C+ G T + R GP C GF G+G C D++EC+ P C C N
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP 731
Query: 147 PGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNC-VP-NSVCINTRGSF 204
FRCE C GY G A +++ IN CETG HNC +P + CI T GS
Sbjct: 732 GTFRCE-CVEGYQ---FSDEGTCVAVVDQR---PINYCETGLHNCDIPQRAQCIYTGGSS 784
Query: 205 QCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGI 264
C PGF GD CQ + PS CH A C GS +C C G+ G+G
Sbjct: 785 YTCSCLPGFSGD-GQACQD-----VDECQPSRCHPDAFC-YNTPGSFTCQCKPGYQGDGF 837
Query: 265 LC 266
C
Sbjct: 838 RC 839
Score = 56.6 bits (135), Expect = 8e-08
Identities = 32/79 (40%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 86 RPLLHCAPGF--C-FPGVA-CIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVR 141
RP+ +C G C P A CI T + C GF+G+G C DV+EC C P
Sbjct: 757 RPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAF 816
Query: 142 CINTSPGFRCEACPPGYSG 160
C NT F C+ C PGY G
Sbjct: 817 CYNTPGSFTCQ-CKPGYQG 834
Score = 54.3 bits (129), Expect = 4e-07
Identities = 50/200 (25%), Positives = 77/200 (38%), Gaps = 35/200 (17%)
Query: 134 HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVP 193
+PC+ +T+ AC PG + F + + + C DI+EC C
Sbjct: 670 NPCYIGTHGCDTNA-----ACRPGPRTQFTCECSIGF-RGDGRTCYDIDECSEQPSVCGS 723
Query: 194 NSVCINTRGSFQCGPCQPGFVGDQASGC----QRRAQRFCPDGSPS-ECHEHADCVLERD 248
+++C N G+F+C C G+ C +R +C G + + + A C+
Sbjct: 724 HTICNNHPGTFRC-ECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGG 782
Query: 249 GSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDN-CVTVPNSGQEDVDRDG 307
S +C C G++G+G C +D D C +C D C P S
Sbjct: 783 SSYTCSCLPGFSGDGQAC-QDVD---------ECQPSRCHPDAFCYNTPGS--------- 823
Query: 308 IGDACDPDADGDG---VPNE 324
C P GDG VP E
Sbjct: 824 FTCQCKPGYQGDGFRCVPGE 843
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 85.5 bits (210), Expect = 2e-16
Identities = 69/212 (32%), Positives = 94/212 (44%), Gaps = 37/212 (17%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CTDVNEC--NAHPCFPRVRCINTSPG 148
P C G C RC C GF + C DVNEC N++ C C NT
Sbjct: 1291 PDIC-DGGQCTNIPGEYRC-LCYDGFMASMDMKTCIDVNECDLNSNICMFG-ECENTKGS 1347
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
F C C GYS K CTD++ECE G HNC ++ C+N GSF+C
Sbjct: 1348 FICH-CQLGYS-----------VKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS- 1394
Query: 209 CQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGR 268
C+ G++G +G + C +G+ +C +A CV GS C C+ G+ G+G C
Sbjct: 1395 CREGWIG---NGIKCIDLDECSNGT-HQCSINAQCV-NTPGSYRCACSEGFTGDGFTC-- 1447
Query: 269 DTDLDGFPDEKLRCPE--RQCRKDNCVTVPNS 298
+D+D C E C C+ VP +
Sbjct: 1448 -SDVD-------ECAENINLCENGQCLNVPGA 1471
Score = 79.3 bits (194), Expect = 1e-14
Identities = 59/186 (31%), Positives = 81/186 (43%), Gaps = 26/186 (13%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFR 150
P C G CI T RC C G+T + G+ C D++EC+ P C NT ++
Sbjct: 2457 PNLCTNG-QCINTMGSFRCF-CKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQ 2514
Query: 151 CEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQ 210
C +CP GY + + + C D++EC+T QHNC +C+NT G F C C
Sbjct: 2515 C-SCPRGY-----------VLQEDGKTCKDLDECQTKQHNC--QFLCVNTLGGFTC-KCP 2559
Query: 211 PGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWA--GNGILCGR 268
PGF + C PS C C GS SC C G++ G+ C
Sbjct: 2560 PGFTQHHTACIDNNE---C-GSQPSLCGAKGIC-QNTPGSFSCECQRGFSLDATGLNCED 2614
Query: 269 DTDLDG 274
+ DG
Sbjct: 2615 VDECDG 2620
Score = 74.3 bits (181), Expect = 4e-13
Identities = 92/373 (24%), Positives = 132/373 (35%), Gaps = 77/373 (20%)
Query: 72 CGMQQSVRTGLPSVRPLLHCAPGF--CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVN 129
C + SV+ G + C G C +C+ +C C G+ GNG C D++
Sbjct: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS-CREGWIGNGIKCIDLD 1410
Query: 130 ECN--AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETG 187
EC+ H C +C+NT +RC AC G++G C+D++EC
Sbjct: 1411 ECSNGTHQCSINAQCVNTPGSYRC-ACSEGFTGDGF-------------TCSDVDECAEN 1456
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVL-- 245
+ C N C+N G+++C C+ GF S R C D EC CV
Sbjct: 1457 INLC-ENGQCLNVPGAYRC-ECEMGFTPASDS-------RSCQD--IDECSFQNICVFGT 1505
Query: 246 --ERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDV 303
G C+C G+ + G TD+D D C CV P G+ +
Sbjct: 1506 CNNLPGMFHCICDDGYELDR-TGGNCTDIDECAD------PINCVNGLCVNTP--GRYEC 1556
Query: 304 DRDGIGDACDPD----ADGDG-VPNEKDNCPLVRNPD-----QRNTD------------- 340
+ C PD G G V N NC L P NT+
Sbjct: 1557 N-------CPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCS 1609
Query: 341 -EDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSD 399
WG+ C+ C + + G G + I D C +P Q +
Sbjct: 1610 LGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPI---TIILEDIDECQELPGLCQGGNC 1666
Query: 400 GDGIGDACDNCPQ 412
+ G CPQ
Sbjct: 1667 INTFGSFQCECPQ 1679
Score = 72.0 bits (175), Expect = 2e-12
Identities = 68/218 (31%), Positives = 89/218 (40%), Gaps = 53/218 (24%)
Query: 73 GMQQSVRTGLPSVRPLLHCAP---GFCFPGVACIQTESGARCGPCPAGFTGNGS-HCTDV 128
G Q + TGL + + C G CI T S RC C G+ + + C DV
Sbjct: 479 GGQGPIITGLTILNQTIDICKHHANLCLNG-RCIPTVSSYRC-ECNMGYKQDANGDCIDV 536
Query: 129 NECNAHPCFPRVRCINTSPGFRCEACPPGYSG-PTHQGVGLAFAKANKQVCTDINECETG 187
+EC ++PC C+NT + C+ C G+ PT KQ C DI+EC
Sbjct: 537 DECTSNPC-TNGDCVNTPGSYYCK-CHAGFQRTPT------------KQACIDIDECIQN 582
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCV--- 244
C N C+NT GSFQC C GF DG C +H +C
Sbjct: 583 GVLC-KNGRCVNTDGSFQC-ICNAGF-------------ELTTDG--KNCVDHDECTTTN 625
Query: 245 -------LERDGSRSCVCAVGW--AGNGILCGRDTDLD 273
+ DGS C+C G+ A NG C TD+D
Sbjct: 626 MCLNGMCINEDGSFKCICKPGFVLAPNGRYC---TDVD 660
Score = 68.2 bits (165), Expect = 3e-11
Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 34/204 (16%)
Query: 92 APGFCFPGVACIQTESGARCGPCPAGFTGNG---SHCTDVNECNAHPCFPRV-RCINTSP 147
+P C G+ C+ T C C G+ +C D++EC +P R C+NT
Sbjct: 1122 SPDLCGSGI-CVNTPGSFEC-ECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEG 1179
Query: 148 GFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
F+C+ CP G+ +++ C DINEC + C N C+N G++QC
Sbjct: 1180 SFQCD-CPLGHE-----------LSPSREDCVDINECSLSDNLC-RNGKCVNMIGTYQCS 1226
Query: 208 PCQPGF-VGDQASGCQRRAQRFCPDGS-PSECHEHADCVLERDGSRSCVCAVGWA--GNG 263
C PG+ GC + +G ++C +GS C C+ G+A +G
Sbjct: 1227 -CNPGYQATPDRQGCTDIDECMIMNGGCDTQC-------TNSEGSYECSCSEGYALMPDG 1278
Query: 264 ILCGRDTDLDGFPDEKLRCPERQC 287
C + + PD C QC
Sbjct: 1279 RSCADIDECENNPD---ICDGGQC 1299
Score = 67.8 bits (164), Expect = 4e-11
Identities = 66/199 (33%), Positives = 86/199 (43%), Gaps = 36/199 (18%)
Query: 98 PGVACIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHP--CFPRVRCINTSPGFRCEA 153
PG A +T CG P GFT + D++EC P C V CIN FRCE
Sbjct: 1782 PGTADFKTI----CGNIP-GFTFDIHTGKAVDIDECKEIPGICANGV-CINQIGSFRCE- 1834
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
CP G+S + + L VC DI+EC G + C N+ CIN+ GS++C C GF
Sbjct: 1835 CPTGFS---YNDLLL--------VCEDIDECSNGDNLCQRNADCINSPGSYRC-ECAAGF 1882
Query: 214 VGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLD 273
C R + C + P+ C H CV + GS C+C NG +D +
Sbjct: 1883 KLSPNGACVDRNE--CLE-IPNVC-SHGLCV-DLQGSYQCIC-----HNGFKASQDQTMC 1932
Query: 274 GFPDEKLRCPERQCRKDNC 292
DE C C C
Sbjct: 1933 MDVDE---CERHPCGNGTC 1948
Score = 67.4 bits (163), Expect = 5e-11
Identities = 51/160 (31%), Positives = 68/160 (42%), Gaps = 24/160 (15%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C TE +C CP G+ +G C D++EC + C+NT GF C+ CPPG++
Sbjct: 2506 CKNTEGSYQCS-CPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCK-CPPGFT 2563
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
+ C D NEC + C +C NT GSF C CQ GF D A+
Sbjct: 2564 -------------QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC-ECQRGFSLD-AT 2608
Query: 220 GCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW 259
G C DG+ C +L G C C G+
Sbjct: 2609 GLNCEDVDEC-DGN-HRCQHGCQNIL---GGYRCGCPQGY 2643
Score = 64.7 bits (156), Expect = 3e-10
Identities = 64/225 (28%), Positives = 89/225 (39%), Gaps = 37/225 (16%)
Query: 102 CIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C+ T+ +C C AGF T +G +C D +EC CIN F+C C PG+
Sbjct: 591 CVNTDGSFQC-ICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKC-ICKPGF- 647
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
N + CTD++EC+T N CIN+ GSF+C C PG A
Sbjct: 648 ----------VLAPNGRYCTDVDECQT--PGICMNGHCINSEGSFRC-DCPPGL----AV 690
Query: 220 GCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAG---NGILCGRDTDLDGFP 276
G R C D H + C G + VC + G C + D GF
Sbjct: 691 GMDGRV---CVD-----THMRSTCY---GGIKKGVCVRPFPGAVTKSECCCANPDY-GFG 738
Query: 277 DEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGV 321
+ CP + + + + G RD A DPD +G+
Sbjct: 739 EPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGI 783
Score = 64.7 bits (156), Expect = 3e-10
Identities = 53/182 (29%), Positives = 76/182 (41%), Gaps = 37/182 (20%)
Query: 97 FPGVACIQTESGARCGPCPAGFTGN--GS---------------HCTDVNECNAHPCFPR 139
+ GV C+ T+ + PC G N GS +C D+NEC +P
Sbjct: 2206 YTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCA 2265
Query: 140 VRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNS-VCI 198
RC+NT + C CP GY+ + ++++C D++EC G H+C +C
Sbjct: 2266 FRCMNTFGSYEC-TCPIGYA-----------LREDQKMCKDLDECAEGLHDCESRGMMCK 2313
Query: 199 NTRGSFQCGPCQPGFV-GDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
N G+F C C PG GC + C P C E+ CV GS C C
Sbjct: 2314 NLIGTFMC-ICPPGMARRPDGEGCVDENE--CRT-KPGIC-ENGRCV-NIIGSYRCECNE 2367
Query: 258 GW 259
G+
Sbjct: 2368 GF 2369
Score = 63.2 bits (152), Expect = 9e-10
Identities = 40/114 (35%), Positives = 54/114 (47%), Gaps = 18/114 (15%)
Query: 102 CIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C G RCG CP G+ + + C D NEC+ C NT ++C ACP G+S
Sbjct: 2628 CQNILGGYRCG-CPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKC-ACPSGFS 2685
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
F+ A C D+NEC + ++ C N C NT G + CG C PG+
Sbjct: 2686 FD-------QFSSA----CHDVNECSSSKNPC--NYGCSNTEGGYLCG-CPPGY 2725
Score = 61.2 bits (147), Expect = 3e-09
Identities = 48/135 (35%), Positives = 60/135 (44%), Gaps = 21/135 (15%)
Query: 78 VRTGLPSVRPLLHCA--PGFCFPGVACIQTESGARCGPCPAGFTGNGS--HCTDVNECNA 133
V TG P + + C PG C G C T +C C +GF + +CTD++EC
Sbjct: 1064 VLTGRPFYKDINECKAFPGMCTYG-KCRNTIGSFKCR-CNSGFALDMEERNCTDIDECRI 1121
Query: 134 HP--CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNC 191
P C + C+NT F CE C GY G K C DI+ECE C
Sbjct: 1122 SPDLCGSGI-CVNTPGSFECE-CFEGYES------GFMMMKN----CMDIDECERNPLLC 1169
Query: 192 VPNSVCINTRGSFQC 206
C+NT GSFQC
Sbjct: 1170 -RGGTCVNTEGSFQC 1183
Score = 56.6 bits (135), Expect = 8e-08
Identities = 86/371 (23%), Positives = 116/371 (31%), Gaps = 80/371 (21%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CTDVNECNAHPCFPRVRCINTSPGFR 150
P C G+ C+ + +C C GF + C DV+EC HPC C NT +
Sbjct: 1900 PNVCSHGL-CVDLQGSYQC-ICHNGFKASQDQTMCMDVDECERHPC-GNGTCKNTVGSYN 1956
Query: 151 CEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQ 210
C C PG F + C DI+EC + N C N GSF+C C
Sbjct: 1957 C-LCYPG------------FELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKC-LCN 2002
Query: 211 PGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVL-----------ERDGSRSCVCAVGW 259
G+ PDG C + +CV +GS C+C G+
Sbjct: 2003 EGY-------------ELTPDG--KNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGY 2047
Query: 260 AGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ----EDVDRDGIGDACDPD 315
C + D P+ C +C P Q G C
Sbjct: 2048 EVKSENCIDINECDEDPN--------ICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDT 2099
Query: 316 ADGDGVPN-EKDNCPLVRNPDQRNTDEDK----------WGDACDNCRSQKNDDQKDTDQ 364
N E C + P NT + K WGD C+ C K+D+ D
Sbjct: 2100 RQSFCFTNFENGKCSV---PKAFNTTKAKCCCSKMPGEGWGDPCELC--PKDDEVAFQDL 2154
Query: 365 DGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQ-----A 419
G + R + C P + G CP N D
Sbjct: 2155 CPYGHGTVPSLHD--TREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCV 2212
Query: 420 DVDHDFVGDAC 430
D D +G+ C
Sbjct: 2213 DTDECSIGNPC 2223
Score = 53.5 bits (127), Expect = 7e-07
Identities = 51/175 (29%), Positives = 71/175 (40%), Gaps = 38/175 (21%)
Query: 108 GARCGPCPA-------GFTGNGSHCT----DVNECNAHP--CFPRVRCINTSPGFRCEAC 154
G C PCPA G +G T D+NEC P C + C N +RC C
Sbjct: 738 GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGI-CENLRGSYRCN-C 795
Query: 155 PPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFV 214
GY A+ + C DI+EC + C N +C NT GS+ C C PG+V
Sbjct: 796 NSGYE-----------PDASGRNCIDIDECLVNRLLC-DNGLCRNTPGSYSC-TCPPGYV 842
Query: 215 GDQASGCQRRAQRFCPDGSPSECHEHADCVLERD-GSRSCVCAVG--WAGNGILC 266
R C D + E + + + GS +C C+ G + G++C
Sbjct: 843 -------FRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLIC 890
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/218 (25%), Positives = 73/218 (33%), Gaps = 70/218 (32%)
Query: 102 CIQTESGARCGPCPAG--FTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEA------ 153
C T C CP G F C D+NEC ++PC C N F CE
Sbjct: 826 CRNTPGSYSC-TCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPGSKL 883
Query: 154 -----------------------CPPGYSGPTHQG-----VGLAF--------------- 170
C +G T + +G A+
Sbjct: 884 SSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPR 943
Query: 171 --AKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRF 228
A+ C D+NECE C PN C+N++GSF C C G D R
Sbjct: 944 GLARIKGVTCEDVNECEVFPGVC-PNGRCVNSKGSFHC-ECPEGLTLDGTG-------RV 994
Query: 229 CPDGSPSECH---EHADCVLERDGS---RSCVCAVGWA 260
C D +C+ + +C+ G +C CAVG A
Sbjct: 995 CLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAA 1032
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/219 (26%), Positives = 85/219 (38%), Gaps = 44/219 (20%)
Query: 96 CFPGVACIQTESGARCGPCPAGFT--GNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEA 153
C G+ CI + +C C GF NG +CTDV+EC CIN+ FRC+
Sbjct: 627 CLNGM-CINEDGSFKC-ICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCD- 683
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCIN------TRGSFQCG 207
CPPG + VG+ + +VC D + T + + VC+ T+ C
Sbjct: 684 CPPGLA------VGM-----DGRVCVDTHMRST-CYGGIKKGVCVRPFPGAVTKSECCCA 731
Query: 208 PCQPGFVGDQASGCQRRAQR----FCPD--GSPSECHEHADCVLERD-----------GS 250
GF G+ C + C G + + +C L+ D GS
Sbjct: 732 NPDYGF-GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGS 790
Query: 251 RSCVCAVGWAGNGILCGRD-TDLDGFPDEKLRCPERQCR 288
C C G+ + GR+ D+D +L C CR
Sbjct: 791 YRCNCNSGYEPDA--SGRNCIDIDECLVNRLLCDNGLCR 827
Score = 48.1 bits (113), Expect = 3e-05
Identities = 31/78 (39%), Positives = 41/78 (52%), Gaps = 10/78 (12%)
Query: 101 ACIQTESGARCGPCPAGFTGN--GSHCTDVNECNA--HPCFPRVRCINTSPGFRCEACPP 156
+C T +C CP+GF+ + S C DVNEC++ +PC C NT G+ C CPP
Sbjct: 2668 SCYNTLGSYKCA-CPSGFSFDQFSSACHDVNECSSSKNPC--NYGCSNTEGGYLC-GCPP 2723
Query: 157 GY--SGPTHQGVGLAFAK 172
GY G H G+ F K
Sbjct: 2724 GYYRVGQGHCVSGMGFNK 2741
Score = 40.4 bits (93), Expect = 0.006
Identities = 54/193 (27%), Positives = 70/193 (36%), Gaps = 29/193 (15%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTG-NGSHCTDVNECNAHPCFPRVRC--INTSP 147
CA + F G C E R GPC FT N C + C + C I +
Sbjct: 196 CACVYGFTGPQC---ERDYRTGPC---FTQVNNQMCQ--GQLTGIVCTKTLCCATIGRAW 247
Query: 148 GFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
G CE CP P +G C D++EC+ C + CINT GSF+C
Sbjct: 248 GHPCEMCP-AQPQPCRRGF---IPNIRTGACQDVDECQAIPGICQGGN-CINTVGSFEC- 301
Query: 208 PCQPGF-VGDQASGCQRRAQ-----RFCPDGSPSECHEHADCVLER------DGSRSCVC 255
C G + C+ + C G S CV R DGSR
Sbjct: 302 RCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQ 361
Query: 256 AVGWAGNGILCGR 268
G +G++ GR
Sbjct: 362 RTGMCFSGLVNGR 374
Score = 38.1 bits (87), Expect = 0.030
Identities = 46/176 (26%), Positives = 64/176 (36%), Gaps = 23/176 (13%)
Query: 90 HCAPGFCF--PGVACIQTESGARCGPCPAGFTGNGSHCTDVN-ECNAHPCFPRVRC-INT 145
+C P F GV C+ R G C F G N E C +
Sbjct: 1557 NCPPDFQLNPTGVGCVDN----RVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGK 1612
Query: 146 SPGFRCEACPPGYSGPTHQ----GVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTR 201
+ G CE CPP S + G G + DI+EC+ C + CINT
Sbjct: 1613 AWGNPCETCPPVNSTEYYTLCPGGEGFR-PNPITIILEDIDECQELPGLCQGGN-CINTF 1670
Query: 202 GSFQCGPCQPGFVGDQASGCQRRAQRFCPDG--SPSECHEHADCVLERDGSRSCVC 255
GSFQC Q ++ + C+ + F G P C+ G+ +C+C
Sbjct: 1671 GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL-------GNYTCIC 1719
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 85.1 bits (209), Expect = 2e-16
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 21/190 (11%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAH---PCFPRVRCINTSPGF 149
P C P C+Q +GA C AG++GNG C++V+ C AH C P C +PG
Sbjct: 1421 PRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPC-AHGHGGCSPHANCTKVAPGQ 1479
Query: 150 RCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPC 209
R C GY G + ++C +IN C C ++ CI T C
Sbjct: 1480 RTCTCQDGYMG-------------DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSC 1526
Query: 210 QPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVC-AVGWAGNGILCGR 268
+ G+ GD C+ +G C +A C DG R+C C G+G+ C
Sbjct: 1527 REGYSGDGIRTCELLDPCSKNNGG---CSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRA 1583
Query: 269 DTDLDGFPDE 278
L+ D+
Sbjct: 1584 RVGLELLRDK 1593
Score = 69.7 bits (169), Expect = 9e-12
Identities = 62/205 (30%), Positives = 78/205 (38%), Gaps = 46/205 (22%)
Query: 91 CAPGF--------------------CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNE 130
CAPGF C C+ E ARC C GF G+G CT N
Sbjct: 806 CAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCR-CLDGFEGDGFSCTPSNP 864
Query: 131 CNAHP----CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECET 186
C+ HP C C+ S G C G+SG + +VC I+ECE
Sbjct: 865 CS-HPDRGGCSENAECVPGSLGTHHCTCHKGWSG-------------DGRVCVAIDECEL 910
Query: 187 GQHN-CVPNSVCINTR-GSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCV 244
C +++C G +C C+ GF GD G Q C G+ CH A C
Sbjct: 911 DMRGGCHTDALCSYVGPGQSRC-TCKLGFAGD---GYQCSPIDPCRAGNGG-CHGLATCR 965
Query: 245 LERDGSRSCVCAVGWAGNGILCGRD 269
G R C C G+ G+G C D
Sbjct: 966 AVGGGQRVCTCPPGFGGDGFSCYGD 990
Score = 68.2 bits (165), Expect = 3e-11
Identities = 59/205 (28%), Positives = 77/205 (37%), Gaps = 47/205 (22%)
Query: 91 CAPGFCFPGVACIQTESGA--------RC---GPCPAGFTGNGSHCTDVN----ECNAH- 134
C GF G AC GA RC G C G G+GS D C
Sbjct: 1997 CRSGFA--GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQL 2054
Query: 135 --------PCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECET 186
PC P C G CE C GY G + +VCT + C+
Sbjct: 2055 ELQPVCTPPCAPEAVC---RAGNSCE-CSLGYEG-------------DGRVCTVADLCQD 2097
Query: 187 GQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLE 246
G C ++ C C C P + GD G RA+ C DG C EHA+C+
Sbjct: 2098 GHGGCSEHANCSQVGTMVTC-TCLPDYEGD---GWSCRARNPCTDGHRGGCSEHANCLST 2153
Query: 247 RDGSRSCVCAVGWAGNGILCGRDTD 271
+R C C G+ G+G+ C +++
Sbjct: 2154 GLNTRRCECHAGYVGDGLQCLEESE 2178
Score = 63.5 bits (153), Expect = 7e-10
Identities = 51/189 (26%), Positives = 64/189 (33%), Gaps = 68/189 (35%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTG---NGSHCTD----VNECNAHPCFPRVRCI 143
C PGF G C PCP G G C D EC+ H F
Sbjct: 1320 CCPGFF-----------GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGF------ 1362
Query: 144 NTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGS 203
G CE C G GP CT + +C G
Sbjct: 1363 ---HGTACEVCELGRYGPN---------------CTGVCDCAHGL--------------- 1389
Query: 204 FQCGPCQPGFVGDQASGCQ------RRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
CQ G GD + C R Q+ P +C +A+CV + G+ +C CA
Sbjct: 1390 -----CQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAA 1444
Query: 258 GWAGNGILC 266
G++GNGI C
Sbjct: 1445 GYSGNGIFC 1453
Score = 63.2 bits (152), Expect = 9e-10
Identities = 49/175 (28%), Positives = 63/175 (36%), Gaps = 27/175 (15%)
Query: 96 CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACP 155
C C RC P G+T GS C N C PC +C + G CP
Sbjct: 204 CPQNTQCSAEAPSCRCLP---GYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCP 260
Query: 156 PGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNS-VCINTRGSFQCGPCQPGFV 214
Y G + VC + C C NS +C+ + C+PG V
Sbjct: 261 ENYHG-------------DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLV 307
Query: 215 G---DQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
+ ++GC FC SP C A C + DG SCVC G+G C
Sbjct: 308 SINSNASAGCFA----FC---SPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
Score = 56.2 bits (134), Expect = 1e-07
Identities = 52/189 (27%), Positives = 73/189 (38%), Gaps = 30/189 (15%)
Query: 102 CIQTESGARCGPCPAGFT----GNGSHCTDVNECNAHPCFPR---VRC-INTSPGFRCEA 153
C + G C CP GF+ G G+ + A CFP + C I ++P E
Sbjct: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQ 779
Query: 154 CP-------------PGYSGPTHQGV---GLAFAKANKQVCTDINECETGQHNCVPNSVC 197
C PG G QG G + N+ + D QH C ++ C
Sbjct: 780 CQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESM-GDCGPTGLAQH-CHLHARC 837
Query: 198 INTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
++ G +C C GF GD G C C E+A+CV G+ C C
Sbjct: 838 VSQEGVARCR-CLDGFEGD---GFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 893
Query: 258 GWAGNGILC 266
GW+G+G +C
Sbjct: 894 GWSGDGRVC 902
Score = 52.8 bits (125), Expect = 1e-06
Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 16/133 (12%)
Query: 87 PLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAH---PCFPRVRCI 143
P H G C C+ G C G++G+G C ++EC C C
Sbjct: 864 PCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCS 923
Query: 144 NTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGS 203
PG C G++G +Q C+ I+ C G C + C G
Sbjct: 924 YVGPGQSRCTCKLGFAGDGYQ-------------CSPIDPCRAGNGGCHGLATCRAVGGG 970
Query: 204 FQCGPCQPGFVGD 216
+ C PGF GD
Sbjct: 971 QRVCTCPPGFGGD 983
Score = 51.6 bits (122), Expect = 3e-06
Identities = 49/180 (27%), Positives = 67/180 (37%), Gaps = 29/180 (16%)
Query: 96 CFPGVACIQTESGARC--GPCPAGFTGNGSHCTD-VNECN----AHPCFPRVRCINTSPG 148
C G+ + SG C G C GF+G C + + +C A C RC++
Sbjct: 786 CVHGLCDNRPGSGGVCQQGTCAPGFSGR--FCNESMGDCGPTGLAQHCHLHARCVSQEGV 843
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE-TGQHNCVPNSVCI-NTRGSFQC 206
RC C G+ G CT N C + C N+ C+ + G+ C
Sbjct: 844 ARCR-CLDGFEGDGFS-------------CTPSNPCSHPDRGGCSENAECVPGSLGTHHC 889
Query: 207 GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILC 266
C G+ GD G A C CH A C G C C +G+AG+G C
Sbjct: 890 -TCHKGWSGD---GRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQC 945
Score = 49.3 bits (116), Expect = 1e-05
Identities = 53/185 (28%), Positives = 61/185 (32%), Gaps = 39/185 (21%)
Query: 148 GFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG 207
G C+ACP G S P C+D C G GS QC
Sbjct: 1965 GSECQACPGGPSSP----------------CSDRGVCMDGM------------SGSGQC- 1995
Query: 208 PCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCG 267
C+ GF G C A F P C H C GS SC C GW G
Sbjct: 1996 LCRSGFAGTACELCAPGA--FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC--- 2050
Query: 268 RDTDLDGFPDEKLRC-PERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKD 326
+ L+ P C PE CR N + D + D C DG G +E
Sbjct: 2051 -EVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQ---DGHGGCSEHA 2106
Query: 327 NCPLV 331
NC V
Sbjct: 2107 NCSQV 2111
Score = 41.2 bits (95), Expect = 0.004
Identities = 56/223 (25%), Positives = 79/223 (35%), Gaps = 44/223 (19%)
Query: 101 ACIQTESGARCGPCPAG----FTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEAC-- 154
AC G+RC CP G G+G+ C D + N C C G C+ C
Sbjct: 99 ACCPGYWGSRCHECPGGAETPCNGHGT-CLDGMDRNG-TCV----CQENFRGSACQECQD 152
Query: 155 PPGYS----------------GPTHQGVGLAFAKANKQVC-TDINECETGQHNCVPNSVC 197
P + GP G L FA C ++ C+ + C N+ C
Sbjct: 153 PNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQ--ELRCPQNTQC 210
Query: 198 INTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
S +C P G G + RA C PS C A C + G C C
Sbjct: 211 SAEAPSCRCLP------GYTQQGSECRAPNPC---WPSPCSLLAQCSVSPKGQAQCHCPE 261
Query: 258 GWAGNGILC-GRD---TDLDGFPDEKLRCPERQCRKDNCVTVP 296
+ G+G++C +D +L G P C ++ + C P
Sbjct: 262 NYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRP 304
Score = 36.6 bits (83), Expect = 0.089
Identities = 42/148 (28%), Positives = 51/148 (34%), Gaps = 35/148 (23%)
Query: 197 CINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCA 256
C+ T C P G S CQ CP G S C + C+ GS C+C
Sbjct: 1950 CVTTTWKPSCCP------GHYGSECQA-----CPGGPSSPCSDRGVCMDGMSGSGQCLCR 1998
Query: 257 VGWAGNGI-LC-----------------GR-DTDLDG----FPDEKLRCPERQCRKD-NC 292
G+AG LC GR D L G F DE P + + +
Sbjct: 1999 SGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQP 2058
Query: 293 VTVPNSGQEDVDRDGIGDACDPDADGDG 320
V P E V R G C +GDG
Sbjct: 2059 VCTPPCAPEAVCRAGNSCECSLGYEGDG 2086
>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
sapiens]
Length = 1207
Score = 84.7 bits (208), Expect = 3e-16
Identities = 68/239 (28%), Positives = 92/239 (38%), Gaps = 54/239 (22%)
Query: 52 LRQQVREITFLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARC 111
L+ QV + L T + D Q + V CAP C CI A C
Sbjct: 796 LKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATC 855
Query: 112 GPCPAGFTGNGSHCTDVNECNAH-PCFPRV--RCINTSPGFRCEACPPGYSGPTHQGVGL 168
C GF G+G C+D++EC P P +CINT G+ C C GY QG G+
Sbjct: 856 -QCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCR-CSEGY-----QGDGI 908
Query: 169 AFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRF 228
C DI+EC+ G+H+C N+ C NT G + C +G
Sbjct: 909 H--------CLDIDECQLGEHSCGENASCTNTEGGYTC----------MCAGRLSEPGLI 950
Query: 229 CPDGSP-----------SECHEHADCVLERDG---------------SRSCVCAVGWAG 261
CPD +P S + ++C L DG +C C VG+ G
Sbjct: 951 CPDSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIG 1009
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/140 (29%), Positives = 51/140 (36%), Gaps = 39/140 (27%)
Query: 174 NKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFV-------GDQASGCQRRAQ 226
+++ C D+NEC H C C NT GS+ C C GFV Q C R
Sbjct: 350 DRKYCEDVNECAFWNHGCTLG--CKNTPGSYYC-TCPVGFVLLPDGKRCHQLVSCPRNVS 406
Query: 227 R--------------FCPDGSPSECHEHADCVLERDGSRSCVC-AVGWAGNGILC----G 267
FCP+GS VLERDG C + G LC
Sbjct: 407 ECSHDCVLTSEGPLCFCPEGS----------VLERDGKTCSGCSSPDNGGCSQLCVPLSP 456
Query: 268 RDTDLDGFPDEKLRCPERQC 287
+ D FP L+ E+ C
Sbjct: 457 VSWECDCFPGYDLQLDEKSC 476
Score = 32.3 bits (72), Expect = 1.7
Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 16/91 (17%)
Query: 231 DGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKD 290
D +P C +A C+ E + + +C C G+AG+G LC +D+D +C
Sbjct: 834 DCAPVGCSMYARCISEGEDA-TCQCLKGFAGDGKLC---SDID------------ECEMG 877
Query: 291 NCVTVPNSGQEDVDRDGIGDACDPDADGDGV 321
V P S + G C GDG+
Sbjct: 878 VPVCPPASSKCINTEGGYVCRCSEGYQGDGI 908
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 84.3 bits (207), Expect = 4e-16
Identities = 61/187 (32%), Positives = 86/187 (45%), Gaps = 36/187 (19%)
Query: 91 CAPG-FCFPGVACIQTESGARCGPCPAGFT---GNGSHCTDVNECNA--HPCFPRVRCIN 144
CA G C C + A C C +G+ G+ ++C D++EC A H C C+N
Sbjct: 395 CAEGPKCGENSECKNWNTKATC-ECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVN 453
Query: 145 TSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSF 204
+RC+ C PGY + + CT+ +EC +GQHNC N++C NT
Sbjct: 454 LPGLYRCD-CVPGY------------IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGH 500
Query: 205 QCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGI 264
C C+PG+VG +G RA FC +G C CV CVC G+ G+
Sbjct: 501 SC-TCKPGYVG---NGTICRA--FCEEG----CRYGGTCV----APNKCVCPSGFTGSH- 545
Query: 265 LCGRDTD 271
C +D D
Sbjct: 546 -CEKDID 551
Score = 60.5 bits (145), Expect = 6e-09
Identities = 67/250 (26%), Positives = 82/250 (32%), Gaps = 43/250 (17%)
Query: 64 NTVMECDACGMQQSVRTGLPSVRPLLHCAPG--FCFPGVACIQTESGARCGPCPAGFTGN 121
NT C+ SV+ + CA +C C+ RC P +
Sbjct: 411 NTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVD 470
Query: 122 GSHCTDVNECNA--HPCFPRVRCINTSPGFRCEACPPGYSGP-------THQGV--GLAF 170
CT+ +EC + H C C NT G C C PGY G +G G
Sbjct: 471 DFSCTEHDECGSGQHNCDENAICTNTVQGHSC-TCKPGYVGNGTICRAFCEEGCRYGGTC 529
Query: 171 AKANKQVCT----------DINECETGQHNCVPNSVCINTRGSFQC-GPCQPGFVGDQAS 219
NK VC DI+EC H C +S CIN G F C P P GD
Sbjct: 530 VAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGD--- 586
Query: 220 GCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDT-DLDGFPDE 278
CP + H L+ D C C G I C R D +
Sbjct: 587 ---------CPHEGGLK-HNGQVWTLKEDRCSVCSCKDG----KIFCRRTACDCQNPSAD 632
Query: 279 KLRCPERQCR 288
CPE R
Sbjct: 633 LFCCPECDTR 642
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 84.3 bits (207), Expect = 4e-16
Identities = 61/187 (32%), Positives = 86/187 (45%), Gaps = 36/187 (19%)
Query: 91 CAPG-FCFPGVACIQTESGARCGPCPAGFT---GNGSHCTDVNECNA--HPCFPRVRCIN 144
CA G C C + A C C +G+ G+ ++C D++EC A H C C+N
Sbjct: 395 CAEGPKCGENSECKNWNTKATC-ECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVN 453
Query: 145 TSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSF 204
+RC+ C PGY + + CT+ +EC +GQHNC N++C NT
Sbjct: 454 LPGLYRCD-CVPGY------------IRVDDFSCTEHDECGSGQHNCDENAICTNTVQGH 500
Query: 205 QCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGI 264
C C+PG+VG +G RA FC +G C CV CVC G+ G+
Sbjct: 501 SC-TCKPGYVG---NGTICRA--FCEEG----CRYGGTCV----APNKCVCPSGFTGSH- 545
Query: 265 LCGRDTD 271
C +D D
Sbjct: 546 -CEKDID 551
Score = 66.2 bits (160), Expect = 1e-10
Identities = 63/213 (29%), Positives = 78/213 (36%), Gaps = 42/213 (19%)
Query: 91 CAPGFCFPGVACIQ-TESGARCGP---------CPAGFTGNGSHCT-DVNECNAH--PCF 137
C PG+ G C E G R G CP+GFTG SHC D++EC+ C
Sbjct: 504 CKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTG--SHCEKDIDECSEGIIECH 561
Query: 138 PRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVC 197
RC+N + CE + T+ G + C DI+EC H C +S C
Sbjct: 562 NHSRCVNLPGWYHCECRSGFHDDGTYSLSG--------ESCIDIDECALRTHTCWNDSAC 613
Query: 198 INTRGSFQC-GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCA 256
IN G F C P P GD CP + H L+ D C C
Sbjct: 614 INLAGGFDCLCPSGPSCSGD------------CPHEGGLK-HNGQVWTLKEDRCSVCSCK 660
Query: 257 VGWAGNGILCGRDT-DLDGFPDEKLRCPERQCR 288
G I C R D + CPE R
Sbjct: 661 DG----KIFCRRTACDCQNPSADLFCCPECDTR 689
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 84.3 bits (207), Expect = 4e-16
Identities = 78/236 (33%), Positives = 99/236 (41%), Gaps = 36/236 (15%)
Query: 91 CAPG---FCFPGVACIQTESGARCGPCPAGFTGNGS--HCTDVNECNAHPCFPRVRCINT 145
CA G C PG C+ G RC C G+ + S +CTD NEC PC + RCIN
Sbjct: 848 CAAGATNVCGPGT-CVNLPDGYRC-VCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINR 905
Query: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQ 205
+ C C PGY+ LA + A Q C DINECE Q C NT GS+
Sbjct: 906 VGSYSC-FCYPGYT--------LATSGAT-QECQDINECE--QPGVCSGGQCTNTEGSYH 953
Query: 206 CGPCQPGFVGDQASGCQR----RAQRFCPDGSPSECHEHADCVLERDGSR----SCVCAV 257
C C G++ + CQ R CPDG C+ +G R SCV
Sbjct: 954 C-ECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVN 1012
Query: 258 GWAGNGILC-GRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDAC 312
G+ G+ T+L+G RC C + VT G +DVD +C
Sbjct: 1013 ECLTPGVCAHGKCTNLEG----SFRC---SCEQGYEVTSDEKGCQDVDECASRASC 1061
Score = 83.2 bits (204), Expect = 8e-16
Identities = 67/243 (27%), Positives = 92/243 (37%), Gaps = 68/243 (27%)
Query: 54 QQVREITFLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGP 113
+Q E+T + + D C + S TGL C+ TE C
Sbjct: 1037 EQGYEVTSDEKGCQDVDECASRASCPTGL-------------------CLNTEGSFACSA 1077
Query: 114 CPAGFTGN--GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGY------------- 158
C G+ N G+ C D++EC P C NT+ F C+ C GY
Sbjct: 1078 CENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVD 1137
Query: 159 ----------SGPTHQGVG-------LAFAKANKQVCTDINECETGQHNCVPNSVCINTR 201
G VG F AN VC D+NEC G+ +C P+ C+N+
Sbjct: 1138 ECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNEC-MGEEHCAPHGECLNSH 1196
Query: 202 GSFQCGPCQPGFV-GDQASGCQRRAQRFCPDGSPSECHEHADCV----LERDGSRSCVCA 256
GSF C C PGFV + + CQ EC CV + +GS +C+C
Sbjct: 1197 GSFFC-LCAPGFVSAEGGTSCQ----------DVDECATTDPCVGGHCVNTEGSFNCLCE 1245
Query: 257 VGW 259
G+
Sbjct: 1246 TGF 1248
Score = 77.4 bits (189), Expect = 5e-14
Identities = 71/248 (28%), Positives = 92/248 (37%), Gaps = 50/248 (20%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTG-NGSHCTDVNECNAHPCFPRVRCINTSPGFRC 151
PG C G C TE C C G+ HC D+NEC P RC+N+ + C
Sbjct: 937 PGVCSGG-QCTNTEGSYHC-ECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTC 994
Query: 152 EACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQP 211
AC GY G + C D+NEC T + C N GSF+C C+
Sbjct: 995 LACEEGYRGQSGS-------------CVDVNECLT--PGVCAHGKCTNLEGSFRCS-CEQ 1038
Query: 212 GF-VGDQASGCQRRAQRFCPDGSPSECHEHADC----VLERDGSRSC-VCAVG-WAGNGI 264
G+ V GCQ EC A C L +GS +C C G W
Sbjct: 1039 GYEVTSDEKGCQ----------DVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDG 1088
Query: 265 LCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVD----RDGIGDACDPDADGDG 320
D D FP CP C T + +D D +GD+C+ D D
Sbjct: 1089 TACEDLDECAFPGV---CPSGVCTN----TAGSFSCKDCDGGYRPSPLGDSCE---DVDE 1138
Query: 321 VPNEKDNC 328
+ + +C
Sbjct: 1139 CEDPQSSC 1146
Score = 70.1 bits (170), Expect = 7e-12
Identities = 109/474 (22%), Positives = 157/474 (33%), Gaps = 125/474 (26%)
Query: 99 GVACIQTESGARCGPCPAGFT-GNGSHCTDVNECNAHP-CFPRVRCINTSPGFRCEACPP 156
G C T +C CP GF NG+ C DVNEC C P C+N+ F C C P
Sbjct: 1148 GGECKNTVGSYQC-LCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFC-LCAP 1205
Query: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
G+ + C D++EC T CV C+NT GSF C C+ GF
Sbjct: 1206 GF-----------VSAEGGTSCQDVDECATTDP-CVGGH-CVNTEGSFNC-LCETGFQPS 1251
Query: 217 QASG-------CQRRAQRFC-------------------------PDG---------SPS 235
SG C+ C P+G + +
Sbjct: 1252 PESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDT 1311
Query: 236 ECHEHADCVLERDGSRSCVCAVGW-----------------------------AGNGILC 266
C H C DGS C+C G+ LC
Sbjct: 1312 MCGSHGFCD-NTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLC 1370
Query: 267 GRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKD 326
+DL+ + ++ C R +G + + GD D +K
Sbjct: 1371 LCASDLEEYDAQEGHCRPR-----------GAGGQSMSEAPTGDHAPAPTRMDCYSGQKG 1419
Query: 327 NCP----LVRNPDQRN---TDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDD--IDG 377
+ P L RN Q T WGDACD C S+ + + + G+G + G
Sbjct: 1420 HAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFG 1479
Query: 378 DRIRNQADNC----PRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGD-ACDS 432
+ AD C P + + + + G C+ + DHD D AC++
Sbjct: 1480 QTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACEN 1539
Query: 433 DQ--DQDGDGH---------QDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDND 475
+ + +G H S+ C +S ++ DHD D C ND
Sbjct: 1540 GECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTND 1593
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 22/105 (20%)
Query: 115 PAGFTG-NGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKA 173
PAGF G C +N C RC+ G+ C+ C G+ A
Sbjct: 1726 PAGFEGLQAEECGILNGCE------NGRCVRVREGYTCD-CFEGFQ-----------LDA 1767
Query: 174 NKQVCTDINECE--TGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
C D+NEC+ G + C NT GS++C C PG+V +
Sbjct: 1768 AHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC-HCSPGYVAE 1811
Score = 43.9 bits (102), Expect = 6e-04
Identities = 46/160 (28%), Positives = 62/160 (38%), Gaps = 24/160 (15%)
Query: 74 MQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGAR------CGPCPAGFTGNGSHCTD 127
++ SV T P P L +PG I SG P P G G +
Sbjct: 503 VENSVETRPP---PWLPASPGHSLWDSNNIPARSGEPPRPLPPAAPRPRGLLGR-CYLNT 558
Query: 128 VNECNAHPCFPRVR---CINTSPGF----RCEACPPGYSGPTHQGVGL----AFAKANKQ 176
VN A+P C + F C CPP + P + L + + N
Sbjct: 559 VNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLT 618
Query: 177 VCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
C DINEC T ++ C+NTRGS+ C C+PG + D
Sbjct: 619 HCQDINECLT--LGLCKDAECVNTRGSYLC-TCRPGLMLD 655
Score = 40.4 bits (93), Expect = 0.006
Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CTDVNECNAHPCFPRVRCINTSPGFR 150
PG C P C+ T G C C GF + SH C D +EC C C+NT F
Sbjct: 1494 PGLC-PNGRCLNTVPGYVC-LCNPGFHYDASHKKCEDHDECQDLAC-ENGECVNTEGSFH 1550
Query: 151 CEACPP 156
C PP
Sbjct: 1551 CFCSPP 1556
Score = 33.1 bits (74), Expect = 0.98
Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 12/82 (14%)
Query: 181 INECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSP---SEC 237
I+ C G N C+N ++C C PG+ +Q +C D + C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRC-VCSPGYQ-------LHPSQAYCTDDNECLRDPC 896
Query: 238 HEHADCVLERDGSRSCVCAVGW 259
C+ R GS SC C G+
Sbjct: 897 KGKGRCI-NRVGSYSCFCYPGY 917
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 84.3 bits (207), Expect = 4e-16
Identities = 68/199 (34%), Positives = 82/199 (41%), Gaps = 28/199 (14%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNEC--NAHPCFPRVRCINTSPG 148
P C G C G RC C GF T + C DV+EC N H C C NT
Sbjct: 1204 PRVCDQG-HCTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICL-HGDCENTKGS 1260
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
F C C GY + C+D++ECE G HNC ++ C+N GSF C
Sbjct: 1261 FVCH-CQLGY-----------MVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-R 1307
Query: 209 CQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGR 268
C PG+VGD G + C C DC L GS C C G+AG+G C
Sbjct: 1308 CLPGWVGD---GFECHDLDECV-SQEHRCSPRGDC-LNVPGSYRCTCRQGFAGDGFFC-- 1360
Query: 269 DTDLDGFPDEKLRCPERQC 287
D D + C QC
Sbjct: 1361 -EDRDECAENVDLCDNGQC 1378
Score = 72.4 bits (176), Expect = 1e-12
Identities = 53/169 (31%), Positives = 69/169 (40%), Gaps = 42/169 (24%)
Query: 102 CIQTESGARCGPCPAGFTGN-GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSG 160
C+ T S RC C G+T + C DV+EC + PC C+N + C C PG+
Sbjct: 424 CLPTPSSYRC-ECNVGYTQDVRGECIDVDECTSSPCH-HGDCVNIPGTYHCR-CYPGFQ- 479
Query: 161 PTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASG 220
A +Q C D++EC C C+NT GSFQC C GF
Sbjct: 480 ----------ATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQC-VCNAGF------- 520
Query: 221 CQRRAQRFCPDGSPSECHEHADCV----------LERDGSRSCVCAVGW 259
PDG C +H +C L DGS SC+C G+
Sbjct: 521 ------ELSPDG--KNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGF 561
Score = 71.2 bits (173), Expect = 3e-12
Identities = 62/197 (31%), Positives = 81/197 (41%), Gaps = 38/197 (19%)
Query: 86 RPLLH-CAPGFCFPGVACIQTESGARCGPCPAGFT--GNGSHCTDVNECNAHPCFPRVRC 142
R L H CA G CI + RC C AG+T + C D++EC+ P C
Sbjct: 2368 RMLAHLCAHG------ECINSLGSFRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFLC 2420
Query: 143 INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRG 202
NT F C +CP GY + + + C D++EC + QHNC +C+NT G
Sbjct: 2421 KNTKGSFLC-SCPRGY-----------LLEEDGRTCKDLDECTSRQHNC--QFLCVNTVG 2466
Query: 203 SFQCGPCQPGFVGDQASGCQRRAQRFCPD---GSPSECHEHADCVLERDGSRSCVCAVGW 259
+F C C PGF Q F D P C H C GS C C G+
Sbjct: 2467 AFTC-RCPPGFT-------QHHQACFDNDECSAQPGPCGAHGHC-HNTPGSFRCECHQGF 2517
Query: 260 --AGNGILCGRDTDLDG 274
+G C + DG
Sbjct: 2518 TLVSSGHGCEDVNECDG 2534
Score = 66.2 bits (160), Expect = 1e-10
Identities = 104/411 (25%), Positives = 150/411 (36%), Gaps = 73/411 (17%)
Query: 92 APGFCFPGVACIQTESGARCGPCPAGFTGNG--SHCTDVNECNAHPCFPR-VRCINTSPG 148
+P C G C+ T C P +G +C DV+EC P R C NT
Sbjct: 1035 SPDLCGQGT-CVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGS 1093
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
++C+ CPPG+ A C DI+EC C P+ C+N G+FQC
Sbjct: 1094 YKCQ-CPPGHE-----------LTAKGTACEDIDECSLSDGLC-PHGQCVNVIGAFQCS- 1139
Query: 209 CQPGFVG-DQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWA--GNGIL 265
C GF GC + +G C H + +GS C C G++ +G
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGG---CDVHC---INTEGSYRCSCGQGYSLMPDGRA 1193
Query: 266 CGRDTDLDGFPDEKLRCPE--RQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPN 323
C D+D C E R C + +C +P G + DG D D
Sbjct: 1194 C---ADVD-------ECEENPRVCDQGHCTNMP-GGHRCLCYDGFMATPDMRTCVD---- 1238
Query: 324 EKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQ 383
D C L + E+ G +C+ + T G D + ++ G +
Sbjct: 1239 -VDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSH 1294
Query: 384 ADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQD 443
A +C +P S +GD + C HD D C S + H+
Sbjct: 1295 A-SCLNIPGSFSCRCLPGWVGDGFE-C------------HDL--DECVSQE------HRC 1332
Query: 444 S-RDNCPTVPNSAQEDSDHDGQGDA--CDDDDDNDGVPDSRDNCRLVPNPG 491
S R +C VP S + GD C+D D+ D DN + + PG
Sbjct: 1333 SPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPG 1383
Score = 65.1 bits (157), Expect = 2e-10
Identities = 82/321 (25%), Positives = 114/321 (35%), Gaps = 66/321 (20%)
Query: 96 CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEA 153
C P C+ RC C GF G+G C D +EC N C +C+N G+RCE
Sbjct: 1332 CSPRGDCLNVPGSYRC-TCRQGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCE- 1388
Query: 154 CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
C G+ PT + + C D++EC G N C N G F+C C G+
Sbjct: 1389 CEMGFD-PTE----------DHRACQDVDECAQG--NLCAFGSCENLPGMFRC-ICNGGY 1434
Query: 214 VGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLD 273
D+ G C D +EC + +C+ + C+ G LC D +
Sbjct: 1435 ELDRGGG-------NCTD--INECADPVNCI-----NGVCINTPG----SYLCSCPQDFE 1476
Query: 274 GFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRN 333
P + C + R NC E DR G +C + G GV C L R
Sbjct: 1477 LNP-SGVGCVD--TRAGNCFL------ETHDRGDSGISCSAEI-GVGVTRASCCCSLGR- 1525
Query: 334 PDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIR---NQADNCPRV 390
WG+ C+ C + + G G +RI D C +
Sbjct: 1526 ---------AWGNPCELCPMANTTEYRTLCPGGEG------FQPNRITVILEDIDECQEL 1570
Query: 391 PNSDQKDSDGDGIGDACDNCP 411
P Q + G CP
Sbjct: 1571 PGLCQGGDCVNTFGSFQCECP 1591
Score = 64.7 bits (156), Expect = 3e-10
Identities = 55/186 (29%), Positives = 75/186 (40%), Gaps = 44/186 (23%)
Query: 97 FPGVACIQTES---GARCGP-------------CPAGFT-GNGSHCTDVNECNAHPCFPR 139
F G+ C+ T+ G CG C GF G C D++EC+ +P
Sbjct: 2119 FTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCA 2178
Query: 140 VRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSV-CI 198
RC NT + C CP GY+ + + +C D++EC GQ +C + C
Sbjct: 2179 FRCHNTEGSYLC-TCPAGYT-----------LREDGAMCRDVDECADGQQDCHARGMECK 2226
Query: 199 NTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHAD-CV----LERDGSRSC 253
N G+F C C PG SG C D +ECH D CV + GS C
Sbjct: 2227 NLIGTFAC-VCPPGMRPLPGSG------EGCTD--DNECHAQPDLCVNGRCVNTAGSFRC 2277
Query: 254 VCAVGW 259
C G+
Sbjct: 2278 DCDEGF 2283
Score = 63.9 bits (154), Expect = 5e-10
Identities = 98/402 (24%), Positives = 136/402 (33%), Gaps = 66/402 (16%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGFTGNGSH--CTDVNECNAHPCFPRVRCINTSPGFR 150
P C G C+ TE C C GF + C D++EC+ PC C N +
Sbjct: 1813 PNVCSHG-DCMDTEGSYMC-LCHRGFQASADQTLCMDIDECDRQPC-GNGTCKNIIGSYN 1869
Query: 151 CEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQ 210
C C PG+ TH G C D +EC T C+NT GSF C CQ
Sbjct: 1870 C-LCFPGFV-VTHNGD-----------CVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQ 1915
Query: 211 PGF-VGDQASGCQRRAQRFCPDGS--PSECHEHADCVLERDGSRSCVCAVGWAGNGILCG 267
GF + C + G+ P C +GS C+C G+ C
Sbjct: 1916 DGFELTADGKNCVDTNECLSLAGTCLPGTCQN-------LEGSFRCICPPGFQVQSDHC- 1967
Query: 268 RDTDLDGFPDEKLRCPERQCRKD----NCVTVP-----NSGQEDVDRDGIGDACDPDADG 318
D+D +E C C C+ P ++G D +A
Sbjct: 1968 --IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGK 2025
Query: 319 DGVPNE----KDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDD 374
VP K C + P + WGD C+ C + + ++ G G D
Sbjct: 2026 CSVPKAFNTTKTRCCCSKRPGEG------WGDPCELCPQEGSAAFQELCPFGHGAVPGPD 2079
Query: 375 IDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQ 434
+ + A+N N ++DG C+ CP DF G C D
Sbjct: 2080 DSREDVNECAENPGVCTNGVCVNTDG---SFRCE-CP-------FGYSLDFTGINC-VDT 2127
Query: 435 DQDGDGHQDSRDNCPTVPNS---AQEDSDHDGQGDACDDDDD 473
D+ GH + C V A D G C+D D+
Sbjct: 2128 DECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDE 2169
Score = 63.2 bits (152), Expect = 9e-10
Identities = 51/175 (29%), Positives = 78/175 (44%), Gaps = 31/175 (17%)
Query: 127 DVNECNAHPCF-PRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE 185
D++EC P CIN FRCE CP G++ + + LA C D++EC
Sbjct: 1721 DIDECGEIPAICANGICINQIGSFRCE-CPAGFN---YNSILLA--------CEDVDECG 1768
Query: 186 TGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVL 245
+ + C N+ CIN GS++C C G+ C R + C + P+ C H DC +
Sbjct: 1769 SRESPCQQNADCINIPGSYRC-KCTRGYKLSPGGACVGRNE--CRE-IPNVC-SHGDC-M 1822
Query: 246 ERDGSRSCVCAVGW--AGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNS 298
+ +GS C+C G+ + + LC D+D C + C C + S
Sbjct: 1823 DTEGSYMCLCHRGFQASADQTLC---MDID-------ECDRQPCGNGTCKNIIGS 1867
Score = 61.6 bits (148), Expect = 3e-09
Identities = 51/199 (25%), Positives = 73/199 (36%), Gaps = 43/199 (21%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C T+ C CP G+ +G C D++EC + + C+NT F C CPPG++
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCR-CPPGFT 2477
Query: 160 GPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQAS 219
+ Q C D +EC C + C NT GSF+C C GF +
Sbjct: 2478 -------------QHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSG 2523
Query: 220 -----------------GCQRRAQRF---CPDGSP-----SECHEHADCVLERDGSRSCV 254
GCQ + + CP G ++C + +C L S
Sbjct: 2524 HGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSAS 2583
Query: 255 CAVGWAGNGILCGRDTDLD 273
C G +C D D
Sbjct: 2584 CRNTLGGFRCVCPSGFDFD 2602
Score = 57.4 bits (137), Expect = 5e-08
Identities = 66/237 (27%), Positives = 84/237 (35%), Gaps = 46/237 (19%)
Query: 94 GFCFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRC 151
G C G C+ TE +C C AGF + +G +C D NEC C+N F C
Sbjct: 498 GLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSC 555
Query: 152 EACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQP 211
C PG+ C DI+EC+T CV N C NT GSF+C C
Sbjct: 556 -LCKPGF-----------LLAPGGHYCMDIDECQT-PGICV-NGHCTNTEGSFRC-QCLG 600
Query: 212 GF-VGDQASGCQRRAQRFCPDGSPSECH---EHADCVLERDGS---RSCVCAVGWAGNGI 264
G VG C R S C+ E C G+ C CA
Sbjct: 601 GLAVGTDGRVCVDTHVR-------STCYGAIEKGSCARPFPGTVTKSECCCA-------- 645
Query: 265 LCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGV 321
GF + CP + + + G RD A DP+ +GV
Sbjct: 646 -----NPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGV 697
Score = 53.9 bits (128), Expect = 5e-07
Identities = 40/115 (34%), Positives = 51/115 (44%), Gaps = 19/115 (16%)
Query: 102 CIQTESGARCGPCPAGFTGNG--SHCTDVNECN-AHPCFPRVRCINTSPGFRCEACPPGY 158
C G RC CP GFT + + C D NEC + P C NT GFRC CP G+
Sbjct: 2542 CQNQLGGYRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRC-VCPSGF 2599
Query: 159 SGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGF 213
Q +G C +++EC + C + C NT G F CG C G+
Sbjct: 2600 D--FDQALG---------GCQEVDECAGRRGPC--SYSCANTPGGFLCG-CPQGY 2640
Score = 52.8 bits (125), Expect = 1e-06
Identities = 66/254 (25%), Positives = 88/254 (34%), Gaps = 78/254 (30%)
Query: 89 LHCAPGFCFPGVACIQTESGARCGPCPAGFT--GNGSHCTDVNECNAHPCFPRVRCINTS 146
L C G+C Q G+ CP GF + C DV+EC + PC V C N +
Sbjct: 733 LLCDNGWC-------QNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGV-CRNLA 784
Query: 147 PGFRCEACPPGYSGPTH------------------------QGVGL-------------- 168
+ C+ P P+ QG L
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 169 -------------AFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVG 215
FA+ C D+NECE+ C PN C+NT GSF+C C G +
Sbjct: 845 PCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCVNTAGSFRC-ECPEGLML 902
Query: 216 DQASGCQRRAQRFCPDGSPSECH---EHADCVLERDGSRS---CVCAVGWAGNGILCGRD 269
D ASG R C D C + +C + G C C++G A G+ C
Sbjct: 903 D-ASG------RLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIG-AVWGVECEAC 954
Query: 270 TDLDGFPDEKLRCP 283
D + L CP
Sbjct: 955 PDPESLEFASL-CP 967
Score = 48.5 bits (114), Expect = 2e-05
Identities = 62/218 (28%), Positives = 81/218 (37%), Gaps = 55/218 (25%)
Query: 114 CPAGFTG-NGSHCTDVNECNAHP-CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFA 171
C GF G C DVNEC + P P RC+NT+ FRCE CP G
Sbjct: 855 CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCE-CPEG-----------LML 902
Query: 172 KANKQVCTDI-----------NECETGQHNCVPNSVCINTRGS---FQCGPCQPGFVGDQ 217
A+ ++C D+ +EC VC + G+ +C C +
Sbjct: 903 DASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEF 962
Query: 218 ASGCQRR---AQRFCPDGSP-----SECH------EHADCVLERDGSRSCVCAVGWAGNG 263
AS C R A R G P +EC H C GS C CA G+A
Sbjct: 963 ASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTC-RNTVGSFHCACAGGFA--- 1018
Query: 264 ILCGRD---TDLDGFPDEKLRCPERQCRKDNCVTVPNS 298
L ++ TD+D + R C + CV P S
Sbjct: 1019 -LDAQERNCTDID-----ECRISPDLCGQGTCVNTPGS 1050
Score = 47.8 bits (112), Expect = 4e-05
Identities = 58/229 (25%), Positives = 85/229 (37%), Gaps = 36/229 (15%)
Query: 93 PGFCFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHP--CFPRVRCINTSPG 148
PG C G C+ T +C CP G+ + + C D++EC+ H C P C NT
Sbjct: 1571 PGLC-QGGDCVNTFGSFQC-ECPPGYHLSEHTRICEDIDECSTHSGICGPGT-CYNTLGN 1627
Query: 149 FRCEACPPGYSGPT----------------HQGV---GLAFAKANKQVCTDINECETGQH 189
+ C CP Y + G LAF K C N +
Sbjct: 1628 YTC-VCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNR 1686
Query: 190 NCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDG 249
C I+ CG PGF+ D +G C + P+ C + C+ + G
Sbjct: 1687 PCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDE-CGE-IPAIC-ANGICI-NQIG 1742
Query: 250 SRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNS 298
S C C G+ N IL + D+D + C + +C+ +P S
Sbjct: 1743 SFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNA----DCINIPGS 1786
Score = 47.8 bits (112), Expect = 4e-05
Identities = 43/165 (26%), Positives = 59/165 (35%), Gaps = 65/165 (39%)
Query: 114 CPAGFT---GNGSHCTDVNECNAHPCF-PRVRCINTSPGFRCEACPPGYS---------- 159
CP G G+G CTD NEC+A P RC+NT+ FRC+ C G+
Sbjct: 2236 CPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCD-CDEGFQPSPTLTECHD 2294
Query: 160 --------------------------------------GPTHQGVGLAFAKANKQVC--- 178
GP + L A +++C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG 2354
Query: 179 -------TDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
D++EC H C + CIN+ GSF+C CQ G+ D
Sbjct: 2355 SGYTAEGRDVDECRMLAHLCA-HGECINSLGSFRC-HCQAGYTPD 2397
Score = 40.0 bits (92), Expect = 0.008
Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 28/211 (13%)
Query: 96 CFPGVACIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEA 153
C GV C+ + C C GF G +C D++EC C NT FRC+
Sbjct: 541 CVNGV-CLNEDGSFSC-LCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQ- 597
Query: 154 CPPGYSGPTHQGVGL-AFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCG-PCQP 211
C G + T V + ++ + C V S C G PCQ
Sbjct: 598 CLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQL 657
Query: 212 GFVGDQASGCQRRAQRFCPD--GSPSECHEHADCVLERD-----------GSRSCVCAVG 258
D A Q C G ++ + +C L+ + GS CVC +G
Sbjct: 658 CPAKDSA-----EFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLG 712
Query: 259 WAGNGILCGRD-TDLDGFPDEKLRCPERQCR 288
+ G+D TD+D L C C+
Sbjct: 713 YEAGA--SGKDCTDVDECALNSLLCDNGWCQ 741
Score = 37.0 bits (84), Expect = 0.068
Identities = 67/254 (26%), Positives = 88/254 (34%), Gaps = 56/254 (22%)
Query: 40 ETNAALQDVRELLRQQVREITFLKNT--VMECDACGMQQSVRTGLPSVRPLLHCA-PGFC 96
E + A QDV E + + +N + C G + R G + + CA P C
Sbjct: 1397 EDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGG-GNCTDINECADPVNC 1455
Query: 97 FPGVACIQTESGARCGPCPAGFTGN--GSHCTDVNECNAHPCF----------------- 137
GV CI T C CP F N G C D N CF
Sbjct: 1456 INGV-CINTPGSYLCS-CPQDFELNPSGVGCVDTRAGN---CFLETHDRGDSGISCSAEI 1510
Query: 138 ----PRVRC---INTSPGFRCEACPPG----YSGPTHQGVGLAFAKANKQVCTDINECET 186
R C + + G CE CP Y G G + + DI+EC+
Sbjct: 1511 GVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITV-ILEDIDECQE 1569
Query: 187 GQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHA----- 241
C C+NT GSFQC C PG+ + + R C D EC H+
Sbjct: 1570 LPGLCQGGD-CVNTFGSFQC-ECPPGYHLSEHT-------RICED--IDECSTHSGICGP 1618
Query: 242 DCVLERDGSRSCVC 255
G+ +CVC
Sbjct: 1619 GTCYNTLGNYTCVC 1632
Score = 31.2 bits (69), Expect = 3.7
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 4/49 (8%)
Query: 113 PCPAGFTGN--GSHCTDVNECNAHPCFPR-VRCINTSPGFRCEACPPGY 158
PC GF N C DV+EC A P + C+N F C CP G+
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCR-CPVGH 278
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 82.8 bits (203), Expect = 1e-15
Identities = 65/200 (32%), Positives = 84/200 (42%), Gaps = 34/200 (17%)
Query: 98 PGVACIQ----TESGARCGP---------CPAGFTGNGSHCTDVNEC--NAHPCFPRVRC 142
PG C ++ ARC P C +G+ G+G +C D NEC H C P C
Sbjct: 759 PGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVC 818
Query: 143 INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVP--NSVCINT 200
IN +RCE C GY + + + N CE G H C P + C++
Sbjct: 819 INLPGSYRCE-CRSGYEFADDRHTCIL-------ITPPANPCEDGSHTCAPAGQARCVHH 870
Query: 201 RGS-FQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW 259
GS F C C PG+ GD G Q C S + CH A C GS SC C G+
Sbjct: 871 GGSTFSCA-CLPGYAGD---GHQCTDVDEC---SENRCHPAATC-YNTPGSFSCRCQPGY 922
Query: 260 AGNGILCGRDTDLDGFPDEK 279
G+G C D+ P E+
Sbjct: 923 YGDGFQCIPDSTSSLTPCEQ 942
Score = 78.2 bits (191), Expect = 3e-14
Identities = 66/215 (30%), Positives = 84/215 (39%), Gaps = 43/215 (20%)
Query: 122 GSHCTDVNECNAHPCFPRVRCI-NTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTD 180
G+ C D +H C RC T + CE C GY G C D
Sbjct: 760 GNPCYD----GSHMCDTTARCHPGTGVDYTCE-CASGYQGDGRN-------------CVD 801
Query: 181 INECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEH 240
NEC TG H C PNSVCIN GS++C C+ G+ + + + P +P E H
Sbjct: 802 ENECATGFHRCGPNSVCINLPGSYRC-ECRSGY---EFADDRHTCILITPPANPCEDGSH 857
Query: 241 -------ADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCR-KDNC 292
A CV + SC C G+AG+G C TD+D C E +C C
Sbjct: 858 TCAPAGQARCVHHGGSTFSCACLPGYAGDGHQC---TDVD-------ECSENRCHPAATC 907
Query: 293 VTVPNSGQEDVDRDGIGDA--CDPDADGDGVPNEK 325
P S GD C PD+ P E+
Sbjct: 908 YNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQ 942
Score = 54.3 bits (129), Expect = 4e-07
Identities = 29/75 (38%), Positives = 35/75 (46%), Gaps = 6/75 (8%)
Query: 91 CAPGFCFPGVA-CIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGF 149
CAP G A C+ C G+ G+G CTDV+EC+ + C P C NT F
Sbjct: 859 CAPA----GQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSF 914
Query: 150 RCEACPPGYSGPTHQ 164
C C PGY G Q
Sbjct: 915 SCR-CQPGYYGDGFQ 928
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 82.0 bits (201), Expect = 2e-15
Identities = 56/172 (32%), Positives = 74/172 (43%), Gaps = 30/172 (17%)
Query: 102 CIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRC-EACPPGYSG 160
C CG C G+ G C DVNEC + C P C NT G++C + CP G +
Sbjct: 5206 CFNAIGSFHCG-CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMT- 5263
Query: 161 PTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASG 220
KA C DI+EC+ G H C N +C NTRGS++C C G+ ++ G
Sbjct: 5264 -----------KAENGTCIDIDECKDGTHQCRYNQICENTRGSYRC-VCPRGY---RSQG 5308
Query: 221 CQRRAQRFCPDGSPSECHE----HADCVLERDGSRSCVCAVG--WAGNGILC 266
R P +EC + A GS C+C G G+G C
Sbjct: 5309 VGR------PCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSC 5354
Score = 73.2 bits (178), Expect = 9e-13
Identities = 42/110 (38%), Positives = 54/110 (49%), Gaps = 17/110 (15%)
Query: 114 CPAGFTGNGSHCTDVNEC-NAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAK 172
CP G + C D++EC N C + C NT ++C CPPGY TH G
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDAC--QHECKNTFGSYQC-ICPPGYQ-LTHNG------- 5467
Query: 173 ANKQVCTDINECETGQHNCVPNSVCINTRGSFQC--GPCQPGFVGDQASG 220
+ C DI+EC +C PN +C N RGS+QC PC P + D SG
Sbjct: 5468 ---KTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSG 5514
Score = 70.1 bits (170), Expect = 7e-12
Identities = 53/154 (34%), Positives = 63/154 (40%), Gaps = 21/154 (13%)
Query: 72 CGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARC-GPCPAGFT-GNGSHCTDVN 129
CG + + + C C P C T G +C CP G T C D++
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDID 5274
Query: 130 EC--NAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETG 187
EC H C C NT +RC CP GY QGVG + C DINECE
Sbjct: 5275 ECKDGTHQCRYNQICENTRGSYRC-VCPRGYRS---QGVG--------RPCMDINECEQV 5322
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPG--FVGDQAS 219
C C NT GSF+C C PG +GD S
Sbjct: 5323 PKPCAHQ--CSNTPGSFKC-ICPPGQHLLGDGKS 5353
Score = 67.8 bits (164), Expect = 4e-11
Identities = 77/294 (26%), Positives = 116/294 (39%), Gaps = 51/294 (17%)
Query: 108 GARCGPCPAGFTGN--GSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQ 164
G R CP+GFT + G C D +EC A +PC C N + C +CP G +
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CHNAMGTYYC-SCPKGLT----- 5137
Query: 165 GVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC-GPCQPGFVGDQASGCQR 223
A+ + C DI+EC G+H C C NT GS++C C GF + G
Sbjct: 5138 ------IAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGF-RRTSDGLSC 5190
Query: 224 RAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCP 283
+ C + SP CH+ GS C C G+ G C D++ C
Sbjct: 5191 QDINECQESSP--CHQRC---FNAIGSFHCGCEPGYQLKGRKC---MDVN-------ECR 5235
Query: 284 ERQCRKDNCVTVPNSGQEDVD--RDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDE 341
+ CR D G + +D +G+ A +G + D C + T +
Sbjct: 5236 QNVCRPDQHCKNTRGGYKCIDLCPNGMTKA------ENGTCIDIDEC-------KDGTHQ 5282
Query: 342 DKWGDACDNCR-SQKNDDQKDTDQDGRGDACDDDIDGDRI-RNQADNCPRVPNS 393
++ C+N R S + + G G C D + +++ + A C P S
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGS 5336
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 81.6 bits (200), Expect = 2e-15
Identities = 68/213 (31%), Positives = 89/213 (41%), Gaps = 39/213 (18%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEACPPG 157
C T C C G+ +G C DVNEC +H C CINT FRC+
Sbjct: 190 CRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR---- 244
Query: 158 YSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP---CQPGFV 214
G + C DI+ECE+G HNC+P+ +C NT GSF+C P C+ GF+
Sbjct: 245 -----DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 215 GDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDG 274
D C + C S + C C+ +GS +C N CGR L+
Sbjct: 300 QDALGNCIDINE--CLSIS-APCPIGHTCI-NTEGSYTC------QKNVPNCGRGYHLN- 348
Query: 275 FPDEKLRC--------PERQCRKDN-CVTVPNS 298
+E RC P C K + CV P S
Sbjct: 349 --EEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/191 (27%), Positives = 73/191 (38%), Gaps = 34/191 (17%)
Query: 84 SVRPLLHCAPGF--CFPGVACIQTESGARCGP---CPAGFTGNG-SHCTDVNECNA--HP 135
S + + C G C P C T RC P C +GF + +C D+NEC + P
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAP 318
Query: 136 CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNS 195
C CINT + C+ P H C D++EC C
Sbjct: 319 CPIGHTCINTEGSYTCQKNVPNCGRGYH-------LNEEGTRCVDVDECAPPAEPCGKGH 371
Query: 196 VCINTRGSFQCGPCQPGFVGD-------QASGCQRRAQRFCPDGSPSECHEHADCVLERD 248
C+N+ GSF+C C+ G+ D + CQR R C +C
Sbjct: 372 RCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC----GHKCENTL------- 419
Query: 249 GSRSCVCAVGW 259
GS C C+VG+
Sbjct: 420 GSYLCSCSVGF 430
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 19/122 (15%)
Query: 121 NGSHCTDVNEC----NAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQ 176
+G C D++EC H C RCIN F+C GY N +
Sbjct: 475 DGVTCEDIDECALPTGGHIC--SYRCINIPGSFQCSCPSSGYR-----------LAPNGR 521
Query: 177 VCTDINECETGQHNCVPNSVCINTRGSFQC--GPCQPGFVGDQASGCQRRAQRFCPDGSP 234
C DI+EC TG HNC N C N +G F+C C + A+ ++ ++ P GS
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSS 581
Query: 235 SE 236
E
Sbjct: 582 KE 583
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/177 (29%), Positives = 68/177 (38%), Gaps = 53/177 (29%)
Query: 91 CAPGFCFPGVA--CI-----QTESGARCG------------PCPAGF--TGNGSHCTDVN 129
C G+ F G++ C+ Q G CG C GF + +G C D+N
Sbjct: 384 CKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 130 ECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE--TG 187
EC++ PC C N ++C C GY GV C DI+EC TG
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCY-CRRGYQLSDVDGV----------TCEDIDECALPTG 490
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCV 244
H C + CIN GSFQC C R P+G C + +CV
Sbjct: 491 GHIC--SYRCINIPGSFQC-------------SCPSSGYRLAPNG--RNCQDIDECV 530
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 81.6 bits (200), Expect = 2e-15
Identities = 68/213 (31%), Positives = 89/213 (41%), Gaps = 39/213 (18%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEACPPG 157
C T C C G+ +G C DVNEC +H C CINT FRC+
Sbjct: 190 CRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR---- 244
Query: 158 YSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP---CQPGFV 214
G + C DI+ECE+G HNC+P+ +C NT GSF+C P C+ GF+
Sbjct: 245 -----DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 215 GDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDG 274
D C + C S + C C+ +GS +C N CGR L+
Sbjct: 300 QDALGNCIDINE--CLSIS-APCPIGHTCI-NTEGSYTC------QKNVPNCGRGYHLN- 348
Query: 275 FPDEKLRC--------PERQCRKDN-CVTVPNS 298
+E RC P C K + CV P S
Sbjct: 349 --EEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/191 (27%), Positives = 73/191 (38%), Gaps = 34/191 (17%)
Query: 84 SVRPLLHCAPGF--CFPGVACIQTESGARCGP---CPAGFTGNG-SHCTDVNECNA--HP 135
S + + C G C P C T RC P C +GF + +C D+NEC + P
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAP 318
Query: 136 CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNS 195
C CINT + C+ P H C D++EC C
Sbjct: 319 CPIGHTCINTEGSYTCQKNVPNCGRGYH-------LNEEGTRCVDVDECAPPAEPCGKGH 371
Query: 196 VCINTRGSFQCGPCQPGFVGD-------QASGCQRRAQRFCPDGSPSECHEHADCVLERD 248
C+N+ GSF+C C+ G+ D + CQR R C +C
Sbjct: 372 RCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC----GHKCENTL------- 419
Query: 249 GSRSCVCAVGW 259
GS C C+VG+
Sbjct: 420 GSYLCSCSVGF 430
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/177 (29%), Positives = 68/177 (38%), Gaps = 53/177 (29%)
Query: 91 CAPGFCFPGVA--CI-----QTESGARCG------------PCPAGF--TGNGSHCTDVN 129
C G+ F G++ C+ Q G CG C GF + +G C D+N
Sbjct: 384 CKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 130 ECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE--TG 187
EC++ PC C N ++C C GY GV C DI+EC TG
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCY-CRRGYQLSDVDGV----------TCEDIDECALPTG 490
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCV 244
H C + CIN GSFQC C R P+G C + +CV
Sbjct: 491 GHIC--SYRCINIPGSFQC-------------SCPSSGYRLAPNG--RNCQDIDECV 530
Score = 58.2 bits (139), Expect = 3e-08
Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 17/90 (18%)
Query: 121 NGSHCTDVNEC----NAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQ 176
+G C D++EC H C RCIN F+C GY N +
Sbjct: 475 DGVTCEDIDECALPTGGHIC--SYRCINIPGSFQCSCPSSGYR-----------LAPNGR 521
Query: 177 VCTDINECETGQHNCVPNSVCINTRGSFQC 206
C DI+EC TG HNC N C N +G F+C
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 40.4 bits (93), Expect = 0.006
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 8/64 (12%)
Query: 102 CIQTESGARCGPCPAG---FTGNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEA--C 154
CI +C CP+ NG +C D++EC H C C N GFRC A C
Sbjct: 498 CINIPGSFQCS-CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFEC 556
Query: 155 PPGY 158
P Y
Sbjct: 557 PENY 560
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 81.6 bits (200), Expect = 2e-15
Identities = 68/213 (31%), Positives = 89/213 (41%), Gaps = 39/213 (18%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEACPPG 157
C T C C G+ +G C DVNEC +H C CINT FRC+
Sbjct: 190 CRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR---- 244
Query: 158 YSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP---CQPGFV 214
G + C DI+ECE+G HNC+P+ +C NT GSF+C P C+ GF+
Sbjct: 245 -----DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 215 GDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDG 274
D C + C S + C C+ +GS +C N CGR L+
Sbjct: 300 QDALGNCIDINE--CLSIS-APCPIGHTCI-NTEGSYTC------QKNVPNCGRGYHLN- 348
Query: 275 FPDEKLRC--------PERQCRKDN-CVTVPNS 298
+E RC P C K + CV P S
Sbjct: 349 --EEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/191 (27%), Positives = 73/191 (38%), Gaps = 34/191 (17%)
Query: 84 SVRPLLHCAPGF--CFPGVACIQTESGARCGP---CPAGFTGNG-SHCTDVNECNA--HP 135
S + + C G C P C T RC P C +GF + +C D+NEC + P
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAP 318
Query: 136 CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNS 195
C CINT + C+ P H C D++EC C
Sbjct: 319 CPIGHTCINTEGSYTCQKNVPNCGRGYH-------LNEEGTRCVDVDECAPPAEPCGKGH 371
Query: 196 VCINTRGSFQCGPCQPGFVGD-------QASGCQRRAQRFCPDGSPSECHEHADCVLERD 248
C+N+ GSF+C C+ G+ D + CQR R C +C
Sbjct: 372 RCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC----GHKCENTL------- 419
Query: 249 GSRSCVCAVGW 259
GS C C+VG+
Sbjct: 420 GSYLCSCSVGF 430
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/177 (29%), Positives = 68/177 (38%), Gaps = 53/177 (29%)
Query: 91 CAPGFCFPGVA--CI-----QTESGARCG------------PCPAGF--TGNGSHCTDVN 129
C G+ F G++ C+ Q G CG C GF + +G C D+N
Sbjct: 384 CKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 130 ECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE--TG 187
EC++ PC C N ++C C GY GV C DI+EC TG
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCY-CRRGYQLSDVDGV----------TCEDIDECALPTG 490
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCV 244
H C + CIN GSFQC C R P+G C + +CV
Sbjct: 491 GHIC--SYRCINIPGSFQC-------------SCPSSGYRLAPNG--RNCQDIDECV 530
Score = 58.2 bits (139), Expect = 3e-08
Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 17/90 (18%)
Query: 121 NGSHCTDVNEC----NAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQ 176
+G C D++EC H C RCIN F+C GY N +
Sbjct: 475 DGVTCEDIDECALPTGGHIC--SYRCINIPGSFQCSCPSSGYR-----------LAPNGR 521
Query: 177 VCTDINECETGQHNCVPNSVCINTRGSFQC 206
C DI+EC TG HNC N C N +G F+C
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRC 551
Score = 40.4 bits (93), Expect = 0.006
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 8/64 (12%)
Query: 102 CIQTESGARCGPCPAG---FTGNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEA--C 154
CI +C CP+ NG +C D++EC H C C N GFRC A C
Sbjct: 498 CINIPGSFQCS-CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFEC 556
Query: 155 PPGY 158
P Y
Sbjct: 557 PENY 560
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 81.6 bits (200), Expect = 2e-15
Identities = 68/213 (31%), Positives = 89/213 (41%), Gaps = 39/213 (18%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRCEACPPG 157
C T C C G+ +G C DVNEC +H C CINT FRC+
Sbjct: 190 CRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQR---- 244
Query: 158 YSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP---CQPGFV 214
G + C DI+ECE+G HNC+P+ +C NT GSF+C P C+ GF+
Sbjct: 245 -----DSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 215 GDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDG 274
D C + C S + C C+ +GS +C N CGR L+
Sbjct: 300 QDALGNCIDINE--CLSIS-APCPIGHTCI-NTEGSYTC------QKNVPNCGRGYHLN- 348
Query: 275 FPDEKLRC--------PERQCRKDN-CVTVPNS 298
+E RC P C K + CV P S
Sbjct: 349 --EEGTRCVDVDECAPPAEPCGKGHRCVNSPGS 379
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/191 (27%), Positives = 73/191 (38%), Gaps = 34/191 (17%)
Query: 84 SVRPLLHCAPGF--CFPGVACIQTESGARCGP---CPAGFTGNG-SHCTDVNECNA--HP 135
S + + C G C P C T RC P C +GF + +C D+NEC + P
Sbjct: 259 SCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAP 318
Query: 136 CFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNS 195
C CINT + C+ P H C D++EC C
Sbjct: 319 CPIGHTCINTEGSYTCQKNVPNCGRGYH-------LNEEGTRCVDVDECAPPAEPCGKGH 371
Query: 196 VCINTRGSFQCGPCQPGFVGD-------QASGCQRRAQRFCPDGSPSECHEHADCVLERD 248
C+N+ GSF+C C+ G+ D + CQR R C +C
Sbjct: 372 RCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC----GHKCENTL------- 419
Query: 249 GSRSCVCAVGW 259
GS C C+VG+
Sbjct: 420 GSYLCSCSVGF 430
Score = 63.5 bits (153), Expect = 7e-10
Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 30/129 (23%)
Query: 121 NGSHCTDVNEC----NAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQ 176
+G C D++EC H C RCIN F+C GY N +
Sbjct: 475 DGVTCEDIDECALPTGGHIC--SYRCINIPGSFQCSCPSSGYR-----------LAPNGR 521
Query: 177 VCTDINECETGQHNCVPNSVCINTRGSFQC--GPCQPGFVGDQASGCQRRAQRFCPDGSP 234
C DI+EC TG HNC N C N +G F+C C + A+ C+R
Sbjct: 522 NCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCER----------- 570
Query: 235 SECHEHADC 243
CHE+ +C
Sbjct: 571 LPCHENREC 579
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/177 (29%), Positives = 68/177 (38%), Gaps = 53/177 (29%)
Query: 91 CAPGFCFPGVA--CI-----QTESGARCG------------PCPAGF--TGNGSHCTDVN 129
C G+ F G++ C+ Q G CG C GF + +G C D+N
Sbjct: 384 CKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDIN 443
Query: 130 ECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE--TG 187
EC++ PC C N ++C C GY GV C DI+EC TG
Sbjct: 444 ECSSSPCSQE--CANVYGSYQCY-CRRGYQLSDVDGV----------TCEDIDECALPTG 490
Query: 188 QHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCV 244
H C + CIN GSFQC C R P+G C + +CV
Sbjct: 491 GHIC--SYRCINIPGSFQC-------------SCPSSGYRLAPNG--RNCQDIDECV 530
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 80.9 bits (198), Expect = 4e-15
Identities = 111/459 (24%), Positives = 158/459 (34%), Gaps = 80/459 (17%)
Query: 80 TGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPR 139
TG P + CAP C G C Q+ C GF G +V++C H C
Sbjct: 190 TGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE-VNVDDCPGHRCLNG 248
Query: 140 VRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCT-DINECETGQHNCVPNSVCI 198
C++ + C+ CPP ++G Q CT D++EC+ + C C
Sbjct: 249 GTCVDGVNTYNCQ-CPPEWTG---------------QFCTEDVDECQLQPNACHNGGTCF 292
Query: 199 NTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVG 258
NT G C C G+ G+ S + D + + C A C +R S C C +G
Sbjct: 293 NTLGGHSC-VCVNGWTGESCS-------QNIDDCATAVCFHGATC-HDRVASFYCACPMG 343
Query: 259 WAGNGILCGRDTDLDGFPDEKLRCPERQCRKDN-CVTVPNSGQEDVDRDGIGDACDPDAD 317
G+LC D C C +D C T P +G+ C P
Sbjct: 344 --KTGLLCHLDD----------ACVSNPCHEDAICDTNPVNGRAIC-------TCPPGFT 384
Query: 318 GDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGR---GDACDDD 374
G + D C + NP C++ N Q GR G C+ D
Sbjct: 385 GGACDQDVDECSIGANP-------------CEHLGRCVNTQGSFLCQCGRGYTGPRCETD 431
Query: 375 ID---GDRIRNQADNCPRVPNSDQKDSDGDGIGDAC----DNCPQKSNPDQADVDHDFV- 426
++ RNQA R+ G G C D C Q S V D V
Sbjct: 432 VNECLSGPCRNQATCLDRIGQFTCICMAG-FTGTYCEVDIDEC-QSSPCVNGGVCKDRVN 489
Query: 427 GDACDSDQDQDGDGHQDSRDNCPTVP--NSAQEDSDHDGQGDACDDDDDNDGVPDSRDNC 484
G +C G Q D C + P N A+ DG C + + + D+C
Sbjct: 490 GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDC 549
Query: 485 RLVPNPGQEDADRDGVGD---VCQDDFDADKVVDKIDVC 520
P+P DG+ C + + ++D C
Sbjct: 550 S--PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDEC 586
Score = 80.1 bits (196), Expect = 7e-15
Identities = 84/319 (26%), Positives = 113/319 (35%), Gaps = 64/319 (20%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSP--G 148
CA CF G C + C CP G TG H D C ++PC C +T+P G
Sbjct: 318 CATAVCFHGATCHDRVASFYCA-CPMGKTGLLCHLDDA--CVSNPCHEDAIC-DTNPVNG 373
Query: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
CPPG++G D++EC G + C C+NT+GSF C
Sbjct: 374 RAICTCPPGFTGGACD--------------QDVDECSIGANPCEHLGRCVNTQGSFLC-Q 418
Query: 209 CQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGR 268
C G+ G + C+ C G C A C L+R G +C+C G+ G C
Sbjct: 419 CGRGYTGPR---CETDVNE-CLSG---PCRNQATC-LDRIGQFTCICMAGFTGT--YCEV 468
Query: 269 DTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNC 328
D D +C+ CV N G +G C G + D C
Sbjct: 469 DID--------------ECQSSPCV---NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC 511
Query: 329 PLV--RN----PDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGD----------ACD 372
RN DQ + E + + + +N D D G AC
Sbjct: 512 ASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACA 571
Query: 373 DDIDGDRIRNQADNCPRVP 391
G R +Q D C P
Sbjct: 572 PGYTGTRCESQVDECRSQP 590
Score = 70.1 bits (170), Expect = 7e-12
Identities = 96/401 (23%), Positives = 131/401 (32%), Gaps = 106/401 (26%)
Query: 80 TGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPC---------------------PAGF 118
T LPS C PG+ G C Q E GPC P GF
Sbjct: 56 TQLPSREAACLCPPGWV--GERC-QLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGF 112
Query: 119 TGNGSHCTDVNECNAHPCFPRVRC-INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQV 177
G C+ + C + PC RC + F C +CPPGY G +
Sbjct: 113 --RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLC-SCPPGYQG--------------RSC 155
Query: 178 CTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSEC 237
+D++EC G+ C C+NT GSF+C C G+ G C+ A +PS C
Sbjct: 156 RSDVDECRVGE-PCRHGGTCLNTPGSFRC-QCPAGYTGPL---CENPA----VPCAPSPC 206
Query: 238 HEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQC-RKDNCVTVP 296
C D + C C G+ G C + D CP +C CV
Sbjct: 207 RNGGTCRQSGDLTYDCACLPGFEGQN--CEVNVD---------DCPGHRCLNGGTCVDGV 255
Query: 297 NSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDN---CRS 353
N+ C P+ G + D C L N AC N C +
Sbjct: 256 NT---------YNCQCPPEWTGQFCTEDVDECQLQPN-------------ACHNGGTCFN 293
Query: 354 QKNDDQKDTDQDGRGDACDDDIDG-------------DRIRNQADNCPRVPNSDQKDSDG 400
G++C +ID DR+ + CP D
Sbjct: 294 TLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDD 353
Query: 401 DGIGDAC-DNCPQKSNPDQ----ADVDHDFVGDACDSDQDQ 436
+ + C ++ +NP F G ACD D D+
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDE 394
Score = 65.1 bits (157), Expect = 2e-10
Identities = 52/184 (28%), Positives = 78/184 (42%), Gaps = 20/184 (10%)
Query: 79 RTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTD-VNECNAHPCF 137
RTG + + C C G C G C C G+ NG +C D V+EC + PC
Sbjct: 1076 RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGY--NGDNCEDDVDECASQPCQ 1132
Query: 138 PRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVC 197
CI+ + C +CPPG G + N+ C ++G C+ N C
Sbjct: 1133 HGGSCIDLVARYLC-SCPPGTLG--------VLCEINEDDCGPGPPLDSGP-RCLHNGTC 1182
Query: 198 INTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
++ G F+C C PG+ G + C+ C G+ H DC+ + G C+C
Sbjct: 1183 VDLVGGFRC-TCPPGYTGLR---CEADINE-CRSGACHAAHTR-DCLQDPGGGFRCLCHA 1236
Query: 258 GWAG 261
G++G
Sbjct: 1237 GFSG 1240
Score = 64.7 bits (156), Expect = 3e-10
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 30/172 (17%)
Query: 91 CA-PGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGF 149
CA P C P C C C G+TG D+N+C+ +PC C + F
Sbjct: 814 CAGPAPCGPHGICTNLAGSFSC-TCHGGYTGPSCD-QDINDCDPNPCLNGGSCQDGVGSF 871
Query: 150 RCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPC 209
C +C PG++GP + D++EC + + C P + C + SF C C
Sbjct: 872 SC-SCLPGFAGP--------------RCARDVDECLS--NPCGPGT-CTDHVASFTC-TC 912
Query: 210 QPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAG 261
PG+ G ++ PD SPS C CV + S SC+C G+ G
Sbjct: 913 PPGYGG-------FHCEQDLPDCSPSSCFNGGTCV-DGVNSFSCLCRPGYTG 956
Score = 57.8 bits (138), Expect = 4e-08
Identities = 52/192 (27%), Positives = 72/192 (37%), Gaps = 24/192 (12%)
Query: 81 GLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCT-DVNECNAHPCFPR 139
G + L C+P CF G C+ + C C G+TG +HC + + C + PC
Sbjct: 918 GFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC-LCRPGYTG--AHCQHEADPCLSRPCLHG 974
Query: 140 VRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCIN 199
C PGFRC C ++GP Q T ++ C + C C+
Sbjct: 975 GVCSAAHPGFRC-TCLESFTGP--------------QCQTLVDWC--SRQPCQNGGRCVQ 1017
Query: 200 TRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW 259
T C P G + D S R A C CV + D S CVC G
Sbjct: 1018 TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV-DEDSSHYCVCPEGR 1076
Query: 260 AGNGILCGRDTD 271
G+ C ++ D
Sbjct: 1077 TGSH--CEQEVD 1086
Score = 55.5 bits (132), Expect = 2e-07
Identities = 84/365 (23%), Positives = 115/365 (31%), Gaps = 95/365 (26%)
Query: 91 CAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFR 150
C+P C G C+ + C C G+TG + V+EC + PC +C++ +
Sbjct: 549 CSPDPCHHG-RCVDGIASFSCA-CAPGYTGTRCE-SQVDECRSQPCRHGGKCLDLVDKYL 605
Query: 151 CEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPN----SVCINTRGSFQC 206
C CP G +G CE +C N VC + + C
Sbjct: 606 CR-CPSGTTGV---------------------NCEVNIDDCASNPCTFGVCRDGINRYDC 643
Query: 207 GPCQPGFVG---------------DQASGCQRRAQRF---CPDGS-------PSECHEHA 241
CQPGF G + C F CP GS PS H
Sbjct: 644 -VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHE 702
Query: 242 DC----VLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPN 297
C + G CVC GW+G RC + R D C + P
Sbjct: 703 PCSHGICYDAPGGFRCVCEPGWSGP------------------RCSQSLAR-DACESQPC 743
Query: 298 SGQEDVDRDGIG--DACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQK 355
DG+G C P G C L+ +P N E G C++ Q
Sbjct: 744 RAGGTCSSDGMGFHCTCPPGVQG-------RQCELL-SPCTPNPCEH--GGRCESAPGQL 793
Query: 356 NDDQKDTDQDGRGDACDDDID---GDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQ 412
Q +G C D+D G C + S G G +CD
Sbjct: 794 --PVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDIN 851
Query: 413 KSNPD 417
+P+
Sbjct: 852 DCDPN 856
Score = 40.4 bits (93), Expect = 0.006
Identities = 37/120 (30%), Positives = 46/120 (38%), Gaps = 25/120 (20%)
Query: 96 CFPGVACIQTESGARCGPCPAGFTG------NGSHCTDVN-ECNAHPCFPRVRC--INTS 146
C GV C QT G RC CP G +G GS N C A PC C +
Sbjct: 1298 CPVGVPCQQTPRGPRCA-CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLA 1356
Query: 147 PGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQC 206
P FRC AC G++GP + A + + C P + C RG +C
Sbjct: 1357 PFFRC-ACAQGWTGPRCEAPAAAPEVSEEPRC--------------PRAACQAKRGDQRC 1401
Score = 33.9 bits (76), Expect = 0.57
Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 37/211 (17%)
Query: 106 ESGARCGPCPAGFTGNG----SHCTD----------VNECNAHPCFPRVRCINTSPGFRC 151
+ G +C P P G G HC C C V C T G RC
Sbjct: 1256 QHGGQCRPSPG--PGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRC 1313
Query: 152 EACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQP 211
ACPPG SGP+ + + A+ C G +C P + F+C C
Sbjct: 1314 -ACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGG--SCRPAPLA----PFFRCA-CAQ 1365
Query: 212 GFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTD 271
G+ G + A P+ S A C +R G + C G CG D
Sbjct: 1366 GWTGPRC-----EAPAAAPEVSEEPRCPRAACQAKR-GDQRCDRECNSPG----CGWD-- 1413
Query: 272 LDGFPDEKLRCPERQCRKDNCVTVPNSGQED 302
G + P RQC C + N+ + D
Sbjct: 1414 -GGDCSLSVGDPWRQCEALQCWRLFNNSRCD 1443
>gi|56550049 uromodulin precursor [Homo sapiens]
Length = 640
Score = 80.1 bits (196), Expect = 7e-15
Identities = 66/198 (33%), Positives = 84/198 (42%), Gaps = 48/198 (24%)
Query: 96 CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC---NAHPCFPRVRCINTSPGFRCE 152
C C + E+ C C GFTG+G C D++EC AH C C+NT F C
Sbjct: 35 CHSNATCTEDEAVTTC-TCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSC- 92
Query: 153 ACPPGYSGPTHQGVGLAFAKANKQVCTDINEC-ETGQHNCVPNSVCINTRGSFQCGPCQP 211
CP G+ G+G CTD++EC E G +C + C+N GS+ C C
Sbjct: 93 VCPEGFR--LSPGLG----------CTDVDECAEPGLSHCHALATCVNVVGSYLC-VCPA 139
Query: 212 GFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCA----------VGWA- 260
G+ GD C+ C SP C DCV E D + VCA W
Sbjct: 140 GYRGD-GWHCE------C---SPGSCGPGLDCVPEGD---ALVCADPCQAHRTLDEYWRS 186
Query: 261 ---GNGILCGRDTDLDGF 275
G G C DTDL G+
Sbjct: 187 TEYGEGYAC--DTDLRGW 202
Score = 66.6 bits (161), Expect = 8e-11
Identities = 49/143 (34%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 126 TDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINEC 184
TD +E C C C C G++G GL C D++EC
Sbjct: 24 TDTSEARWCSECHSNATCTEDEAVTTC-TCQEGFTGD-----GLT--------CVDLDEC 69
Query: 185 ET-GQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADC 243
G HNC NS C+NT GSF C C GF GC + C + S CH A C
Sbjct: 70 AIPGAHNCSANSSCVNTPGSFSC-VCPEGFRLSPGLGCTDVDE--CAEPGLSHCHALATC 126
Query: 244 VLERDGSRSCVCAVGWAGNGILC 266
V GS CVC G+ G+G C
Sbjct: 127 V-NVVGSYLCVCPAGYRGDGWHC 148
>gi|59850812 uromodulin precursor [Homo sapiens]
Length = 640
Score = 80.1 bits (196), Expect = 7e-15
Identities = 66/198 (33%), Positives = 84/198 (42%), Gaps = 48/198 (24%)
Query: 96 CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC---NAHPCFPRVRCINTSPGFRCE 152
C C + E+ C C GFTG+G C D++EC AH C C+NT F C
Sbjct: 35 CHSNATCTEDEAVTTC-TCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSC- 92
Query: 153 ACPPGYSGPTHQGVGLAFAKANKQVCTDINEC-ETGQHNCVPNSVCINTRGSFQCGPCQP 211
CP G+ G+G CTD++EC E G +C + C+N GS+ C C
Sbjct: 93 VCPEGFR--LSPGLG----------CTDVDECAEPGLSHCHALATCVNVVGSYLC-VCPA 139
Query: 212 GFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCA----------VGWA- 260
G+ GD C+ C SP C DCV E D + VCA W
Sbjct: 140 GYRGD-GWHCE------C---SPGSCGPGLDCVPEGD---ALVCADPCQAHRTLDEYWRS 186
Query: 261 ---GNGILCGRDTDLDGF 275
G G C DTDL G+
Sbjct: 187 TEYGEGYAC--DTDLRGW 202
Score = 66.6 bits (161), Expect = 8e-11
Identities = 49/143 (34%), Positives = 59/143 (41%), Gaps = 20/143 (13%)
Query: 126 TDVNECN-AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINEC 184
TD +E C C C C G++G GL C D++EC
Sbjct: 24 TDTSEARWCSECHSNATCTEDEAVTTC-TCQEGFTGD-----GLT--------CVDLDEC 69
Query: 185 ET-GQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADC 243
G HNC NS C+NT GSF C C GF GC + C + S CH A C
Sbjct: 70 AIPGAHNCSANSSCVNTPGSFSC-VCPEGFRLSPGLGCTDVDE--CAEPGLSHCHALATC 126
Query: 244 VLERDGSRSCVCAVGWAGNGILC 266
V GS CVC G+ G+G C
Sbjct: 127 V-NVVGSYLCVCPAGYRGDGWHC 148
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 79.3 bits (194), Expect = 1e-14
Identities = 68/225 (30%), Positives = 92/225 (40%), Gaps = 43/225 (19%)
Query: 91 CAPGF--CFPGVACIQTESGARCGP---CPAGFTGNGS-HCTDVNECNA--HPCFPRVRC 142
CA G C PG C T+ C C GF + +C D+NEC + PC P C
Sbjct: 768 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSC 827
Query: 143 INTSPGFRCEA----CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCI 198
INT + C+ C GY A + C D+NECETG H C VC
Sbjct: 828 INTVGSYTCQRNPLICARGYH-----------ASDDGTKCVDVNECETGVHRCGEGQVCH 876
Query: 199 NTRGSFQCGPCQPGFVGDQ-ASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
N GS++C C+ GF D GC + + G C + L GS C CA
Sbjct: 877 NLPGSYRC-DCKAGFQRDAFGRGCIDVNECWASPG--RLCQHTCENTL---GSYRCSCAS 930
Query: 258 GW--AGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ 300
G+ A +G C ++ C ++C ++ C + S Q
Sbjct: 931 GFLLAADGKRC----------EDVNECEAQRCSQE-CANIYGSYQ 964
Score = 75.5 bits (184), Expect = 2e-13
Identities = 72/250 (28%), Positives = 96/250 (38%), Gaps = 48/250 (19%)
Query: 87 PLLHCAPGFCFPGVACIQ---TESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPR 139
PL P C C Q T G+ C G+ +G C D+NEC + H C
Sbjct: 674 PLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRG 733
Query: 140 VRCINTSPGFRCE---ACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSV 196
C+NT F C C PGY+ + C D++EC G H C P +
Sbjct: 734 EHCVNTLGSFHCYKALTCEPGYALKDGE-------------CEDVDECAMGTHTCQPGFL 780
Query: 197 CINTRGSFQCGP---CQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSC 253
C NT+GSF C C GF+ D C + C S C C+ GS +C
Sbjct: 781 CQNTKGSFYCQARQRCMDGFLQDPEGNCVDINE--CTSLS-EPCRPGFSCI-NTVGSYTC 836
Query: 254 -----VCAVGW--AGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQED---- 302
+CA G+ + +G C D++ RC E Q C +P S + D
Sbjct: 837 QRNPLICARGYHASDDGTKC---VDVNECETGVHRCGEGQV----CHNLPGSYRCDCKAG 889
Query: 303 VDRDGIGDAC 312
RD G C
Sbjct: 890 FQRDAFGRGC 899
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 51/178 (28%)
Query: 102 CIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C T RC C +GF +G C DVNEC A C C N ++C C GY
Sbjct: 917 CENTLGSYRCS-CASGFLLAADGKRCEDVNECEAQRCSQE--CANIYGSYQCY-CRQGYQ 972
Query: 160 ----GPT-------HQGVGLAFA---------------------KANKQVCTDINECETG 187
G T QG G+ AN + C D++EC G
Sbjct: 973 LAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALG 1032
Query: 188 QHNCVPNSVCINTRGSFQC--GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADC 243
HNC C N +GSF+C C P +V + C+R + CH+ +C
Sbjct: 1033 THNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCER-----------TTCHDFLEC 1079
Score = 47.8 bits (112), Expect = 4e-05
Identities = 36/126 (28%), Positives = 46/126 (36%), Gaps = 19/126 (15%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRC--EACP 155
C+ +C G+T NG C DV+EC H C C N FRC CP
Sbjct: 998 CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1057
Query: 156 PGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINT-----RGSFQCGPCQ 210
P Y V ++ K + C D EC+ + T F+ GP
Sbjct: 1058 PNY-------VQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPA- 1109
Query: 211 PGFVGD 216
P F GD
Sbjct: 1110 PAFTGD 1115
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 79.3 bits (194), Expect = 1e-14
Identities = 68/225 (30%), Positives = 92/225 (40%), Gaps = 43/225 (19%)
Query: 91 CAPGF--CFPGVACIQTESGARCGP---CPAGFTGNGS-HCTDVNECNA--HPCFPRVRC 142
CA G C PG C T+ C C GF + +C D+NEC + PC P C
Sbjct: 815 CAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSC 874
Query: 143 INTSPGFRCEA----CPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCI 198
INT + C+ C GY A + C D+NECETG H C VC
Sbjct: 875 INTVGSYTCQRNPLICARGYH-----------ASDDGTKCVDVNECETGVHRCGEGQVCH 923
Query: 199 NTRGSFQCGPCQPGFVGDQ-ASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
N GS++C C+ GF D GC + + G C + L GS C CA
Sbjct: 924 NLPGSYRC-DCKAGFQRDAFGRGCIDVNECWASPG--RLCQHTCENTL---GSYRCSCAS 977
Query: 258 GW--AGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQ 300
G+ A +G C ++ C ++C ++ C + S Q
Sbjct: 978 GFLLAADGKRC----------EDVNECEAQRCSQE-CANIYGSYQ 1011
Score = 72.4 bits (176), Expect = 1e-12
Identities = 64/219 (29%), Positives = 86/219 (39%), Gaps = 44/219 (20%)
Query: 114 CPAGFTGNGSH-CTDVNEC--NAHPCFPRVRCINTSPGFRCE---ACPPGYSGPTHQGVG 167
C G+ N C D+NEC + H C C+NT F C C PGY+ +
Sbjct: 752 CADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGE--- 808
Query: 168 LAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP---CQPGFVGDQASGCQRR 224
C D++EC G H C P +C NT+GSF C C GF+ D C
Sbjct: 809 ----------CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDI 858
Query: 225 AQRFCPDGSPSECHEHADCVLERDGSRSC-----VCAVGW--AGNGILCGRDTDLDGFPD 277
+ C S C C+ GS +C +CA G+ + +G C D++
Sbjct: 859 NE--CTSLS-EPCRPGFSCI-NTVGSYTCQRNPLICARGYHASDDGTKC---VDVNECET 911
Query: 278 EKLRCPERQCRKDNCVTVPNSGQED----VDRDGIGDAC 312
RC E Q C +P S + D RD G C
Sbjct: 912 GVHRCGEGQV----CHNLPGSYRCDCKAGFQRDAFGRGC 946
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 51/178 (28%)
Query: 102 CIQTESGARCGPCPAGF--TGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYS 159
C T RC C +GF +G C DVNEC A C C N ++C C GY
Sbjct: 964 CENTLGSYRCS-CASGFLLAADGKRCEDVNECEAQRCSQE--CANIYGSYQCY-CRQGYQ 1019
Query: 160 ----GPT-------HQGVGLAFA---------------------KANKQVCTDINECETG 187
G T QG G+ AN + C D++EC G
Sbjct: 1020 LAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALG 1079
Query: 188 QHNCVPNSVCINTRGSFQC--GPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADC 243
HNC C N +GSF+C C P +V + C+R + CH+ +C
Sbjct: 1080 THNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCER-----------TTCHDFLEC 1126
Score = 47.8 bits (112), Expect = 4e-05
Identities = 36/126 (28%), Positives = 46/126 (36%), Gaps = 19/126 (15%)
Query: 102 CIQTESGARCGPCPAGFT--GNGSHCTDVNEC--NAHPCFPRVRCINTSPGFRC--EACP 155
C+ +C G+T NG C DV+EC H C C N FRC CP
Sbjct: 1045 CLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1104
Query: 156 PGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINT-----RGSFQCGPCQ 210
P Y V ++ K + C D EC+ + T F+ GP
Sbjct: 1105 PNY-------VQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPA- 1156
Query: 211 PGFVGD 216
P F GD
Sbjct: 1157 PAFTGD 1162
Score = 38.9 bits (89), Expect = 0.018
Identities = 35/134 (26%), Positives = 49/134 (36%), Gaps = 33/134 (24%)
Query: 90 HCAPGFCFPGVACIQTESGARCGP--------------CPAGFTGNGSHCTDVNECNAHP 135
HCA CFPG + + G C P + F+ S+ + +
Sbjct: 628 HCA---CFPGFSL--QDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNT 682
Query: 136 CFPRVRC---INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCV 192
C C +T G +C PGY+ A+ C D +EC G H+C
Sbjct: 683 CKDNGPCKQVCSTVGGSAICSCFPGYA-----------IMADGVSCEDQDECLMGAHDCS 731
Query: 193 PNSVCINTRGSFQC 206
C+NT GSF C
Sbjct: 732 RRQFCVNTLGSFYC 745
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 79.3 bits (194), Expect = 1e-14
Identities = 60/175 (34%), Positives = 78/175 (44%), Gaps = 23/175 (13%)
Query: 96 CFPGVACIQTESGARCGPCPAGFTGN---------GSHCTDVNEC--NAHPCFPRVRCIN 144
C C T C C GF + G C D++EC + PC P C N
Sbjct: 41 CPAYATCTNTVDSYYCA-CKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
Query: 145 TSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSF 204
S ++C +C G+S PT G K CTDINEC T C +S C+N+ GS+
Sbjct: 100 LSGRYKC-SCLDGFSSPT--GNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSY 155
Query: 205 QCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGW 259
C CQ GF+ + S C+ + C D P C EHA C G+ SC C G+
Sbjct: 156 SCS-CQVGFI-SRNSTCEDVDE--CAD--PRACPEHATC-NNTVGNYSCFCNPGF 203
Score = 63.9 bits (154), Expect = 5e-10
Identities = 65/218 (29%), Positives = 85/218 (38%), Gaps = 32/218 (14%)
Query: 24 SPLGSDLGPQMLRELQETNAALQDVRELLRQQV-REITFLKNTVMECDACGMQQSVRTGL 82
SP G+D P + N + D+ E L V E + N+ M +C Q +
Sbjct: 114 SPTGNDWVPG-----KPGNFSCTDINECLTSSVCPEHSDCVNS-MGSYSCSCQVGFISRN 167
Query: 83 PSVRPLLHCA-PGFCFPGVACIQTESGARCGPCPAGFTGNGSH---------CTDVNECN 132
+ + CA P C C T C C GF + H C D++EC
Sbjct: 168 STCEDVDECADPRACPEHATCNNTVGNYSCF-CNPGFESSSGHLSFQGLKASCEDIDECT 226
Query: 133 AHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCV 192
C C NT + C C PG++ Q L F + C DI+EC C
Sbjct: 227 -EMCPINSTCTNTPGSYFC-TCHPGFAPSNGQ---LNFTDQGVE-CRDIDECRQDPSTCG 280
Query: 193 PNSVCINTRGSFQCGPCQPGF----VGDQASG---CQR 223
PNS+C N GS+ CG C GF G Q G CQR
Sbjct: 281 PNSICTNALGSYSCG-CIAGFHPNPEGSQKDGNFSCQR 317
Score = 63.5 bits (153), Expect = 7e-10
Identities = 53/169 (31%), Positives = 68/169 (40%), Gaps = 22/169 (13%)
Query: 122 GSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDI 181
G++C D C A+ C NT + C AC G+ Q K C DI
Sbjct: 32 GNNCRDSTLCPAY-----ATCTNTVDSYYC-ACKQGFLSSNGQN----HFKDPGVRCKDI 81
Query: 182 NECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGC--QRRAQRFCPD----GSPS 235
+EC C PNS C N G ++C C GF + + C D + S
Sbjct: 82 DECSQSPQPCGPNSSCKNLSGRYKCS-CLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
Query: 236 ECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPE 284
C EH+DCV GS SC C VG+ C D+D D + CPE
Sbjct: 141 VCPEHSDCV-NSMGSYSCSCQVGFISRNSTC---EDVDECADPR-ACPE 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,746,340
Number of Sequences: 37866
Number of extensions: 1966470
Number of successful extensions: 9537
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 5866
Number of HSP's gapped (non-prelim): 1799
length of query: 757
length of database: 18,247,518
effective HSP length: 110
effective length of query: 647
effective length of database: 14,082,258
effective search space: 9111220926
effective search space used: 9111220926
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.