Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40217817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40217817 slit and trk like 1 protein [Homo sapiens]
(696 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40217817 slit and trk like 1 protein [Homo sapiens] 1419 0.0
gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens] 544 e-154
gi|27436867 slit and trk like 4 protein [Homo sapiens] 538 e-153
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens] 519 e-147
gi|40217825 slit and trk like 6 [Homo sapiens] 501 e-142
gi|40217820 slit and trk like 3 protein [Homo sapiens] 489 e-138
gi|188528675 slit homolog 1 [Homo sapiens] 135 2e-31
gi|11321571 slit homolog 3 [Homo sapiens] 125 2e-28
gi|4759146 slit homolog 2 [Homo sapiens] 118 2e-26
gi|194440719 chondroadherin-like [Homo sapiens] 108 1e-23
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 100 3e-21
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 99 1e-20
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 99 1e-20
gi|13194201 reticulon 4 receptor precursor [Homo sapiens] 94 3e-19
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 94 4e-19
gi|198041768 synleurin [Homo sapiens] 94 6e-19
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens] 92 2e-18
gi|139948432 adlican [Homo sapiens] 89 1e-17
gi|109150416 peroxidasin [Homo sapiens] 88 2e-17
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 88 2e-17
gi|225579152 insulin-like growth factor binding protein, acid la... 88 3e-17
gi|4826772 insulin-like growth factor binding protein, acid labi... 88 3e-17
>gi|40217817 slit and trk like 1 protein [Homo sapiens]
Length = 696
Score = 1419 bits (3674), Expect = 0.0
Identities = 696/696 (100%), Positives = 696/696 (100%)
Query: 1 MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQF 60
MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQF
Sbjct: 1 MLLWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQF 60
Query: 61 YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS 120
YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS
Sbjct: 61 YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS 120
Query: 121 FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPIT 180
FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPIT
Sbjct: 121 FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPIT 180
Query: 181 HLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVV 240
HLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVV
Sbjct: 181 HLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVV 240
Query: 241 CEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHAT 300
CEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHAT
Sbjct: 241 CEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHAT 300
Query: 301 PGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCN 360
PGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCN
Sbjct: 301 PGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCN 360
Query: 361 NRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFK 420
NRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFK
Sbjct: 361 NRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFK 420
Query: 421 NLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNN 480
NLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNN
Sbjct: 421 NLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNN 480
Query: 481 NLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPF 540
NLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPF
Sbjct: 481 NLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPF 540
Query: 541 KQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLA 600
KQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLA
Sbjct: 541 KQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLA 600
Query: 601 ETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASE 660
ETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASE
Sbjct: 601 ETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASE 660
Query: 661 INSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD 696
INSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD
Sbjct: 661 INSLQTVCDSSYWHNGPYNADGAHRVYDCGSHSLSD 696
>gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]
Length = 845
Score = 544 bits (1401), Expect = e-154
Identities = 289/655 (44%), Positives = 405/655 (61%), Gaps = 26/655 (3%)
Query: 22 DVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANF 81
D+CK + C C E E L+++CE KGFT++ P + Y LFL+GN LTRL+PNEF N+
Sbjct: 27 DICKIR-CLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNY 85
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
NAV+LH+ NNGL EI GAF GL+ +KRLH+NNNK++ R+ TFLGL+ LEYLQAD+N
Sbjct: 86 SNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLEILREDTFLGLESLEYLQADYNY 145
Query: 142 LRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQI 201
+ I+ GAF LNKL+VLILNDNL+ +LP+NVF++V +THLDLRGNRLK +P+ VLE I
Sbjct: 146 ISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMPFAGVLEHI 205
Query: 202 PGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLC 261
GI EI LE+NPW+CTCDLL LK WL+ I +G +VCE P RL GKD+ + T QDLC
Sbjct: 206 GGIMEIQLEENPWNCTCDLLPLKAWLDTI--TVFVGEIVCETPFRLHGKDVTQLTRQDLC 263
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRP 321
P K+ DSS A +T PT P P K +++ RP
Sbjct: 264 PRKSASDSSQRGSHA--DTHVQRLSPT----------MNPALNPTRAPKASRPPKMRNRP 311
Query: 322 TAAIATGSSRNK--PL-------ANSLPCPGGCSC-DHIPGSGLKMNCNNRNVSSLADLK 371
T + R P+ L CP C C +GL +NC R ++++DL+
Sbjct: 312 TPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQ 371
Query: 372 PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMD 431
PK ++ ++L+L N + ++ K+ ++Y +L LL LGNN IA ++ F NL LR LY++
Sbjct: 372 PKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLN 431
Query: 432 SNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
NYL+ L F GLQ+L+YL +EYN I+ I P TF+A+ L++L LNNNLLRSLP ++F
Sbjct: 432 GNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIF 491
Query: 492 AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G +L++L+L NN+F +LPV GVLDQL + IQIDL NPW+C+C I+ K W E S V
Sbjct: 492 GGTALTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPV 551
Query: 552 LMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLD 611
+++++ CE+P + L + ICP T+ S + N+ +SY +
Sbjct: 552 IINEVTCESPAKHAGEILKFLGREAICPDSPNLSDGTVLSMNHNTDTPRSLSVSPSSYPE 611
Query: 612 T-SRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINSLQ 665
+ V +SVL+ GLL+VF+ S G+ VF+L+ RK N++ +++S Q
Sbjct: 612 LHTEVPLSVLILGLLVVFILSVCFGAGLFVFVLKRRKGVPSVPRNTNNLDVSSFQ 666
>gi|27436867 slit and trk like 4 protein [Homo sapiens]
Length = 837
Score = 538 bits (1386), Expect = e-153
Identities = 289/672 (43%), Positives = 410/672 (61%), Gaps = 14/672 (2%)
Query: 1 MLLWILLLETSLCFAAGNVTGDVCKE--KICSCNEIEGDLHVDCEKKGFTSLQRFTAPTS 58
M LW+ L+ ++L ++ N D+ E +CSC +E L+V+CEK + P S
Sbjct: 1 MFLWLFLILSAL-ISSTNADSDISVEICNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWS 59
Query: 59 QFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKI 118
FYHL N L L+PN F NF +AVSLH+ NN L I GAFLGL +K+LH+NNN++
Sbjct: 60 NFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNEL 119
Query: 119 KSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP 178
K R TFLG+++LEYLQAD+NL++ I+ GAF L+KL+VLILNDNLIS LP N+F++
Sbjct: 120 KILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFAS 179
Query: 179 ITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGR 238
+THLD+RGNR++ LPY VLE I + E+ LEDNPW+C+CDLL LK WLEN+P N IG
Sbjct: 180 LTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGE 239
Query: 239 VVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLP-APPAQEETFAPGPLPTPFKTNGQED 297
+CE P+ L G+ L ET +Q+LCP+ D + PP+Q E P +T+
Sbjct: 240 AICETPSDLYGRLLKETNKQELCPMGTGSDFDVRILPPSQLENGYTTPNGHTTQTSLHRL 299
Query: 298 HATPGSAPNGGTKIPG---NWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGS- 353
P N +KI G + R + I + +R PL PCP C C P
Sbjct: 300 VTKPPKTTN-PSKISGIVAGKALSNRNLSQIVSYQTRVPPLT---PCPAPCFCKTHPSDL 355
Query: 354 GLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIAT 413
GL +NC +N+ S+++L PK N ++L + N I + S F D++ L LL LG+N I
Sbjct: 356 GLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITV 415
Query: 414 VENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKL 473
++ + F NL +LR LY++ N ++ L E F+GL NL+YL +EYN I+ I GTF++MP L
Sbjct: 416 IKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNL 475
Query: 474 RILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWEC 533
++L LNNNLL+SLPV +F+G L++L+L NN FMYLPV+GVLDQL S+ QIDL GNPW+C
Sbjct: 476 QLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDC 535
Query: 534 SCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHS 593
+C +V K W E+L +++ +LKCETPV F + L N+ +CP+L + S TS +
Sbjct: 536 TCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPA 595
Query: 594 KNSTGLAETGTHSNSYLDTSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKRSKRRD 653
T G + V +S+L+ +L+V + + F +LVF+LR K+ +
Sbjct: 596 PAITFTTPLGPIRSP--PGGPVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKH 653
Query: 654 ANSSASEINSLQ 665
+ S+Q
Sbjct: 654 EGLGNPDCGSMQ 665
>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
Length = 958
Score = 519 bits (1337), Expect = e-147
Identities = 286/698 (40%), Positives = 427/698 (61%), Gaps = 45/698 (6%)
Query: 1 MLLWILLLETSL---CFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPT 57
ML + TSL C + G++C + C C E +G L V CE +G SL + P
Sbjct: 22 MLQTLAFAVTSLVLSCAETIDYYGEIC-DNACPCEEKDGILTVSCENRGIISLSEISPPR 80
Query: 58 SQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNK 117
YHL L GN L RL+PNEF N+ A LH+ +N + +I GAF GL+ ++RLH+NNNK
Sbjct: 81 FPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNK 140
Query: 118 IKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV 177
++ R TFLGL++LEYLQ D+N + I+P AF L+ L+VLILNDNL+S+LP N+F++V
Sbjct: 141 LELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFV 200
Query: 178 PITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIG 237
P+THLDLRGNRLK LPY +L+ + + E+ LE+NPW+C+C+L+SLK+WL++I +AL+G
Sbjct: 201 PLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVG 260
Query: 238 RVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSL-PAPPAQEETFAPGPLPTPFKTNGQE 296
VVCE P RL G+DL+E ++Q+LCP + D + P P + TP N
Sbjct: 261 DVVCETPFRLHGRDLDEVSKQELCPRRLISDYEMRPQTPLSTTGYLH---TTPASVNSVA 317
Query: 297 DHAT----PGSAPNGGTKIPGNWQIKIRPTAAIAT---GSSRNKPLAN-------SLPCP 342
++ P P GT+ P + ++RPT+ + G S P L CP
Sbjct: 318 TSSSAVYKPPLKPPKGTRQPN--KPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECP 375
Query: 343 GGCSCD-HIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNL 401
CSC+ I GL +NC R + S+A+L+PK N ++++L +N I +R++ F++ L
Sbjct: 376 TACSCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYIAVVRRTDFLEATGL 435
Query: 402 ILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQL 461
LL LGNN I+ +++ F +L +LR LY++ N ++ LS E F GLQ+L+YL ++YN I+
Sbjct: 436 DLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIRE 495
Query: 462 ILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSI 521
I GTF+ +P L++L LNNNLL+++P VF+G++L +L+L +N+F LPV+GVLDQL S+
Sbjct: 496 IQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSL 555
Query: 522 IQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICP-- 579
IQIDLH NPW+C+C IV K W E+L VL+ ++ C+ P F D + ++ +CP
Sbjct: 556 IQIDLHDNPWDCTCDIVGMKLWVEQLKVGVLVDEVICKAPKKFAETDMRSIKSELLCPDY 615
Query: 580 -------------QLYARISPTLTSHSKNSTGL-AETGTHSNSYLDTSRVSISVLVPGLL 625
Q+ AR S + NSTG A G + S V +SVL+ LL
Sbjct: 616 SDVVVSTPTPSSIQVPARTSAVTPAVRLNSTGAPASLGAGGGA----SSVPLSVLILSLL 671
Query: 626 LVFVTSAFTVVGMLVFILRNRKRSKRRDANSSASEINS 663
LVF+ S F G+ V +++ RK+++ +++ S+++S
Sbjct: 672 LVFIMSVFVAAGLFVLVMKRRKKNQSDHTSTNNSDVSS 709
>gi|40217825 slit and trk like 6 [Homo sapiens]
Length = 841
Score = 501 bits (1290), Expect = e-142
Identities = 282/686 (41%), Positives = 402/686 (58%), Gaps = 35/686 (5%)
Query: 1 MLLWILLLETSL--CFAAGNVTGDVCK----EKICSCNEIEGDLHVDCEKKGFTSLQRFT 54
M LWI L +SL C + + T + + +C+C E +G + ++CE KG + +
Sbjct: 1 MKLWIHLFYSSLLACISLHSQTPVLSSRGSCDSLCNCEEKDGTMLINCEAKGIKMVSEIS 60
Query: 55 APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHIN 114
P S+ + L L N LT L N+F+ NA+S+H+ N + +I GAF GL L+K+LHIN
Sbjct: 61 VPPSRPFQLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHIN 120
Query: 115 NNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
+N ++ ++ TF GL++LE+LQAD N + I+P AF LN+L+VLILNDN I +LP N+F
Sbjct: 121 HNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIF 180
Query: 175 QYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNA 234
++VP+THLDLRGN+L+TLPY LE I I ++ LEDN W C CDLL LK WLEN+P +
Sbjct: 181 RFVPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQS 240
Query: 235 LIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAP-GPLPTPFKTN 293
+IG VVC +P +G L+ ++ +C P PP EE P G L
Sbjct: 241 IIGDVVCNSPPFFKGSILSRLKKESIC----------PTPPVYEEHEDPSGSL------- 283
Query: 294 GQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLP---CPGGCSCDHI 350
H S+ N I PT A KP + LP CP C+C +
Sbjct: 284 ----HLAATSSINDSRMSTKTTSILKLPTKAPGLIPYITKP-STQLPGPYCPIPCNCKVL 338
Query: 351 PGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNN 410
SGL ++C RN+ SL+DL+P N ++L L N IHS+ KS V+Y L +L LGNN
Sbjct: 339 SPSGLLIHCQERNIESLSDLRPPPQNPRKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNR 398
Query: 411 IATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAM 470
I +E +F NL L+ LY++ N+L LS+ F GL NLEYL +EYNAI+ ILPGTFN M
Sbjct: 399 IEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPM 458
Query: 471 PKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
PKL++L LNNNLL+ LP +F+GV L+K++L N F +LPV+ +LD L + QIDL NP
Sbjct: 459 PKLKVLYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNP 518
Query: 531 WECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARIS-PTL 589
W+CSC +V +QW ++L + D+ C +P + +K+ L+++ +CP L S PT
Sbjct: 519 WDCSCDLVGLQQWIQKLSKNTVTDDILCTSPGHLDKKELKALNSEILCPGLVNNPSMPTQ 578
Query: 590 TSHSKNSTGLAETGTHSNSYLD-TSRVSISVLVPGLLLVFVTSAFTVVGMLVFILRNRKR 648
TS+ +T T T T V +SVL+ GLL++F+T F G++V +L R+R
Sbjct: 579 TSYLMVTTPATTTNTADTILRSLTDAVPLSVLILGLLIMFITIVFCAAGIVVLVLHRRRR 638
Query: 649 SKRRDANSSASEINSLQTVCDSSYWH 674
K++ + + NS + S Y H
Sbjct: 639 YKKKQVDEQMRD-NSPVHLQYSMYGH 663
>gi|40217820 slit and trk like 3 protein [Homo sapiens]
Length = 977
Score = 489 bits (1260), Expect = e-138
Identities = 274/705 (38%), Positives = 419/705 (59%), Gaps = 35/705 (4%)
Query: 2 LLWILLLETSLCFAAGNVTGDVCKEKI-------CSCNEIEGDLHVDCEKKGFTSLQRFT 54
+LWI+LL T + E+I C C E H+ C+ KGFT++ + T
Sbjct: 14 MLWIILLSTIALGWTTPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQIT 73
Query: 55 APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHIN 114
S+ + L+L NS+ +L+ N F + NAVS+++ NN L +I GAF GL+++KRL+++
Sbjct: 74 EFWSRPFKLYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLH 133
Query: 115 NNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
NK+ FR TFLGL+ LEYLQAD+N+++ I+ GAF++L+KL VLILNDNLI LP N+F
Sbjct: 134 ENKLDVFRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLF 193
Query: 175 QYVPITHLDLRGNRLKTLPYEEVLEQI-PGIAEILLEDNPWDCTCDLLSLKEWLENIPKN 233
+ V +THLDLRGNRLK L Y +L+ I + E+ LE+NPW+CTC+++ LK WLE IP
Sbjct: 194 KAVSLTHLDLRGNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYT 253
Query: 234 ALIGRVVCEAPTRLQGKDLNETTEQDLCPL--KNRVDSSLPAP---PAQEETFAPGP--- 285
AL+G + CE P GKDL E + +LCPL + V++SL P ++E + P
Sbjct: 254 ALVGDITCETPFHFHGKDLREIRKTELCPLLSDSEVEASLGIPHSSSSKENAWPTKPSSM 313
Query: 286 LPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKP------LANSL 339
L + T ++ + P TK P + P+ + A N+P +
Sbjct: 314 LSSVHFTASSVEYKSSNKQPK-PTKQP---RTPRPPSTSQALYPGPNQPPIAPYQTRPPI 369
Query: 340 P--CPGGCSCD-HIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFV 396
P CP GC+C+ HI GL +NC R +++++L P+ N ++L+L N I I +S F
Sbjct: 370 PIICPTGCTCNLHINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNLIQKIYRSDFW 429
Query: 397 DYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEY 456
++ +L LL LGNN I+ V++ F NL +L+ L+++ N ++ L+ F GLQ+L YL E+
Sbjct: 430 NFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEF 489
Query: 457 NAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLD 516
N I+ I P F+ MP L++L LNNNLLR+LP D FAG SL++L+L NYF+YLPVAGVL+
Sbjct: 490 NVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVAGVLE 549
Query: 517 QLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDE 576
L +I+QIDL+ NPW+C+C +VPFKQW E + S ++ D+ C +P N +D + +
Sbjct: 550 HLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDVLCRSPENLTHRDVRTIELEV 609
Query: 577 ICPQLYARISPTLTSHSK-NSTGLAETGTHSNSYLDT---SRVSISVLVPGLLLVFVTSA 632
+CP++ ++P S ++ + L T ++ Y + V +SVL+ LL++F ++
Sbjct: 610 LCPEM-LHVAPAGESPAQPGDSHLIGAPTSASPYEFSPPGGPVPLSVLILSLLVLFFSAV 668
Query: 633 FTVVGMLVFIL-RNRKRSKRRDANSSASEINSLQTVCDSSYWHNG 676
F G+ ++L R RK+ R ++ +Q C + G
Sbjct: 669 FVAAGLFAYVLRRRRKKLPFRSKRQEGVDLTGIQMQCHRLFEDGG 713
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 135 bits (339), Expect = 2e-31
Identities = 154/650 (23%), Positives = 254/650 (39%), Gaps = 144/650 (22%)
Query: 3 LWILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYH 62
LW+LL AA + C +C+C VDC G ++ + ++
Sbjct: 18 LWLLLWA-----AAWRLGASACPA-LCTCTGTT----VDCHGTGLQAIPKNIPRNTE--R 65
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNK----- 117
L L+GN++TR+ N+FA L + N + + GAF ++ ++RL +N N+
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 118 -------------------IKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEV 158
I++ ++ F G DL+ LQ D N + I+ GAF+ L LEV
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 159 LILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTC 218
L LN+N I+T+P + F ++P +L+T L N C C
Sbjct: 186 LTLNNNNITTIPVSSFNHMP---------KLRT---------------FRLHSNHLFCDC 221
Query: 219 DLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQE 278
L L +WL P L + C P L+G ++ E + +
Sbjct: 222 HLAWLSQWLRQRPTIGLFTQ--CSGPASLRGLNVAEVQKSE------------------- 260
Query: 279 ETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANS 338
F +GQ + PT +++GS
Sbjct: 261 -----------FSCSGQGEAGRV-------------------PTCTLSSGS--------- 281
Query: 339 LPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDY 398
CP C+C +G+ ++C + ++++ P+ + E+ L N I SI F Y
Sbjct: 282 --CPAMCTC----SNGI-VDCRGKGLTAIPANLPE--TMTEIRLELNGIKSIPPGAFSPY 332
Query: 399 KNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNA 458
+ L +DL NN IA + + F+ L L L + N + L R F GL L+ L + N
Sbjct: 333 RKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 459 IQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQ 517
I I P F + L +L L +N ++SL F + ++ L L N F + D
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF-------ICDC 445
Query: 518 LTSIIQIDLHGNPWECS-CTIVPFKQWAERLGSEVLMSDLKCETPVNFF---RKDFMLLS 573
+ L NP E S ++ A + ++ +C +F +D+ L S
Sbjct: 446 NLKWLADFLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNS 505
Query: 574 ---NDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVSISVL 620
+D +CP + + S T + E S + L + IS+L
Sbjct: 506 ECNSDVVCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISIL 555
Score = 120 bits (300), Expect = 6e-27
Identities = 113/444 (25%), Positives = 179/444 (40%), Gaps = 67/444 (15%)
Query: 40 VDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVP 99
VDC KG T++ T L L+G + + P F+ + + + NN + EI P
Sbjct: 293 VDCRGKGLTAIPANLPETMTEIRLELNG--IKSIPPGAFSPYRKLRRIDLSNNQIAEIAP 350
Query: 100 GAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVL 159
AF GL+ + L + NKI + F GL L+ L + N + I P AFQDL L +L
Sbjct: 351 DAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLL 410
Query: 160 ILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCD 219
L DN I +L F + I + L NP+ C C+
Sbjct: 411 SLYDNKIQSLAKGTFT------------------------SLRAIQTLHLAQNPFICDCN 446
Query: 220 LLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEE 279
L L ++L P R C +P RL K + + + S A+E+
Sbjct: 447 LKWLADFLRTNPIETSGAR--CASPRRLANKRIGQ------------IKSKKFRCSAKEQ 492
Query: 280 TFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSL 339
F PG + D P K R A + SS +
Sbjct: 493 YFIPGTEDYQLNSECNSDVVCPH---------------KCRCEANVVECSSLK---LTKI 534
Query: 340 PCPGGCSCDHIPGSGLKMNCNNRNVSSL--ADLKPKLSNVQELFLRDNKIHSIRKSHFVD 397
P + IP S ++ NN +S L + KL++++++ L +NK+ I F
Sbjct: 535 P-------ERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEG 587
Query: 398 YKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
++ L L N + ++ + F+ L LR L + +N + + + F GL+N+ L++ N
Sbjct: 588 AASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDN 647
Query: 458 AIQLILPGTFNAMPKLRILILNNN 481
I + PG F+ + L L L N
Sbjct: 648 QITTVSPGAFDTLQSLSTLNLLAN 671
Score = 82.0 bits (201), Expect = 2e-15
Identities = 68/245 (27%), Positives = 103/245 (42%), Gaps = 20/245 (8%)
Query: 300 TPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNC 359
TPG + G P W + AA G+S CP C+C +G ++C
Sbjct: 4 TPGWGSSAGPVRPELWLLLW--AAAWRLGASA---------CPALCTC-----TGTTVDC 47
Query: 360 NNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
+ + ++ P+ N + L L N I I K+ F K L +L L N I VE F
Sbjct: 48 HGTGLQAIPKNIPR--NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAF 105
Query: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
++ +L L ++ N L L F Q L L++ NAIQ I F L+ L L+
Sbjct: 106 DDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLD 165
Query: 480 NNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIV 538
N + + F + L L+L+NN +PV+ + + + LH N C C +
Sbjct: 166 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSS-FNHMPKLRTFRLHSNHLFCDCHLA 224
Query: 539 PFKQW 543
QW
Sbjct: 225 WLSQW 229
Score = 80.5 bits (197), Expect = 5e-15
Identities = 102/419 (24%), Positives = 165/419 (39%), Gaps = 68/419 (16%)
Query: 23 VCKEKICSCNEIEGDLHVDCEKKGFTSL-QRFTAPTSQFYHLFLHGNSLTRL-FPNEFAN 80
VC K C C E ++ V+C T + +R T++ L L+ N ++ L F
Sbjct: 512 VCPHK-CRC---EANV-VECSSLKLTKIPERIPQSTAE---LRLNNNEISILEATGMFKK 563
Query: 81 FYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFN 140
+ +++ NN + EI GAF G V LH+ N+++S R F GLD L L N
Sbjct: 564 LTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNN 623
Query: 141 LLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQ 200
+ I +F L + +L L DN I+T+ F +
Sbjct: 624 RISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAF------------------------DT 659
Query: 201 IPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDL 260
+ ++ + L NP++C C L L WL + + G C+ P L+ L + D
Sbjct: 660 LQSLSTLNLLANPFNCNCQLAWLGGWLRK--RKIVTGNPRCQNPDFLRQIPLQDVAFPDF 717
Query: 261 -CPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTK--IPGNWQI 317
C LP P +E L T + + + A P P T+ + GN Q
Sbjct: 718 RCEEGQEEGGCLPRPQCPQECAC---LDTVVRCSNKHLRALPKGIPKNVTELYLDGN-QF 773
Query: 318 KIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLK-PKLSN 376
+ P S K L ++ +N +SSL++ +S
Sbjct: 774 TLVPGQL-----STFKYLQ-------------------LVDLSNNKISSLSNSSFTNMSQ 809
Query: 377 VQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYL 435
+ L L N + I F ++L LL L N+I+T++ F ++ L L + +N L
Sbjct: 810 LTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 868
Score = 67.8 bits (164), Expect = 3e-11
Identities = 62/244 (25%), Positives = 97/244 (39%), Gaps = 44/244 (18%)
Query: 83 NAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLL 142
N L+++ N +VPG + ++ + ++NNKI S +F + L L +N L
Sbjct: 762 NVTELYLDGNQF-TLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNAL 820
Query: 143 RDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIP 202
+ I P AFQ L L +L L+ N ISTL +F +
Sbjct: 821 QCIPPLAFQGLRSLRLLSLHGNDISTLQEGIF------------------------ADVT 856
Query: 203 GIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDL-- 260
++ + + NP C C L L W++ K I R C P ++GK L T +
Sbjct: 857 SLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIAR--CAGPQDMEGKLLLTTPAKKFEC 914
Query: 261 -----CPLKNRVDSSLPAPPAQEETFAPGPL-------PTPFKTNGQE---DHATPGSAP 305
++ + D L +P + T PL P+ +K E D + G
Sbjct: 915 QGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCE 974
Query: 306 NGGT 309
NGGT
Sbjct: 975 NGGT 978
Score = 62.0 bits (149), Expect = 2e-09
Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 8/143 (5%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C + C+N+++ +L PK NV EL+L N+ ++ +K
Sbjct: 734 CPQECAC-----LDTVVRCSNKHLRALPKGIPK--NVTELYLDGNQF-TLVPGQLSTFKY 785
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L L+DL NN I+++ N++F N+ L L + N L + F GL++L L++ N I
Sbjct: 786 LQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDIS 845
Query: 461 LILPGTFNAMPKLRILILNNNLL 483
+ G F + L L + N L
Sbjct: 846 TLQEGIFADVTSLSHLAIGANPL 868
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 125 bits (313), Expect = 2e-28
Identities = 128/528 (24%), Positives = 210/528 (39%), Gaps = 129/528 (24%)
Query: 6 LLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFL 65
L L +L C K C+C+ VDC G ++ R ++ L L
Sbjct: 16 LALALALASVLSGPPAVACPTK-CTCSAAS----VDCHGLGLRAVPRGIPRNAE--RLDL 68
Query: 66 HGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNK-------- 117
N++TR+ +FA N LH+E+N + I GAF L+ ++RL +N NK
Sbjct: 69 DRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELL 128
Query: 118 ----------------IKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLIL 161
I+ ++ F G+ D++ LQ D N + I+ GAF+ L LE+L L
Sbjct: 129 FQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTL 188
Query: 162 NDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLL 221
N+N IS + F ++P +++TL L N C C L
Sbjct: 189 NNNNISRILVTSFNHMP---------KIRTLR---------------LHSNHLYCDCHLA 224
Query: 222 SLKEWLENIPKNALIGR-VVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEET 280
L +WL + +G+ +C AP L+G ++ A ++E
Sbjct: 225 WLSDWLR---QRRTVGQFTLCMAPVHLRGFNV--------------------ADVQKKEY 261
Query: 281 FAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLP 340
P P H+ P S ANS+
Sbjct: 262 VCPAP------------HSEPPSCN------------------------------ANSIS 279
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C S ++C + + + P+ + E+ L N I +I F YK
Sbjct: 280 CPSPCTC-----SNNIVDCRGKGLMEIPANLPE--GIVEIRLEQNSIKAIPAGAFTQYKK 332
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L +D+ N I+ + + F+ L L L + N + +++ F GL +L+ L + N I
Sbjct: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKIN 392
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFM 507
+ TF + L +L L +N L+++ +FA + S+ L L N F+
Sbjct: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFV 440
Score = 120 bits (301), Expect = 4e-27
Identities = 120/512 (23%), Positives = 200/512 (39%), Gaps = 109/512 (21%)
Query: 85 VSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRD 144
V + +E N + I GAF + +KR+ I+ N+I F GL L L N + +
Sbjct: 310 VEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITE 369
Query: 145 IDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQIPG 203
I G F L L++L+LN N I+ L N FQ + + L L N+L+T+ + + +
Sbjct: 370 IAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTIS-KGLFAPLQS 428
Query: 204 IAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPL 263
I + L NP+ C C L L ++L++ P R C +P RL K +++ +
Sbjct: 429 IQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGAR--CSSPRRLANKRISQIKSK----- 481
Query: 264 KNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTA 323
F+ +G ED+
Sbjct: 482 -------------------------KFRCSGSEDYR------------------------ 492
Query: 324 AIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLR 383
S + L CP C C+ G ++C+N+ + + P+ V +L L
Sbjct: 493 -----SRFSSECFMDLVCPEKCRCE-----GTIVDCSNQKLVRIPSHLPEY--VTDLRLN 540
Query: 384 DNKIHSIRKSH-FVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREK 442
DN++ + + F NL ++L NN I V F ++ L + N L+T+
Sbjct: 541 DNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRV 600
Query: 443 FAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLH 502
F GL L+ L + N I + TF + +R+L L +N + ++
Sbjct: 601 FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTI---------------- 644
Query: 503 NNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPV 562
G L S+ I+L NP+ C+C + +W + ++ + +C+ P
Sbjct: 645 --------TPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRK--RRIVSGNPRCQKP- 693
Query: 563 NFFRK----------DFMLLSNDEICPQLYAR 584
FF K DF N+E QL R
Sbjct: 694 -FFLKEIPIQDVAIQDFTCDGNEESSCQLSPR 724
Score = 76.3 bits (186), Expect = 9e-14
Identities = 94/416 (22%), Positives = 167/416 (40%), Gaps = 63/416 (15%)
Query: 23 VCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFY-HLFLHGNSLTRLFPNE-FAN 80
VC EK C C EG + VDC + L R + ++ L L+ N ++ L F
Sbjct: 504 VCPEK-CRC---EGTI-VDCSNQ---KLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKK 555
Query: 81 FYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFN 140
N +++ NN + E+ GAF G V+ L + N++++ + F GL L+ L N
Sbjct: 556 LPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSN 615
Query: 141 LLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQ 200
L+ + F L+ + +L L DN I+T+ F
Sbjct: 616 LIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAF------------------------TT 651
Query: 201 IPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDL 260
+ ++ I L NP++C C L L +WL + + G C+ P L+ + + QD
Sbjct: 652 LVSLSTINLLSNPFNCNCHLAWLGKWLRK--RRIVSGNPRCQKPFFLKEIPIQDVAIQDF 709
Query: 261 CPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIR 320
N S +P E+ + T + + + A P P T++ ++
Sbjct: 710 TCDGNEESSCQLSPRCPEQCTC---METVVRCSNKGLRALPRGMPKDVTEL----YLEGN 762
Query: 321 PTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLK-PKLSNVQE 379
A+ S + L ++ +N ++S L + +S++
Sbjct: 763 HLTAVPRELSALRHLT-------------------LIDLSNNSISMLTNYTFSNMSHLST 803
Query: 380 LFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYL 435
L L N++ I F ++L +L L N+I++V +F +L L L + +N L
Sbjct: 804 LILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 75.1 bits (183), Expect = 2e-13
Identities = 61/228 (26%), Positives = 100/228 (43%), Gaps = 11/228 (4%)
Query: 317 IKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSN 376
++ R A+A S + P A + CP C+C S ++C+ + ++ P+ N
Sbjct: 12 VRARLALALALASVLSGPPA--VACPTKCTC-----SAASVDCHGLGLRAVPRGIPR--N 62
Query: 377 VQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLD 436
+ L L N I I K F KNL +L L +N ++ +E F++L L L ++ N L
Sbjct: 63 AERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQ 122
Query: 437 TLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-S 495
L F L L++ N IQ I F + ++ L L+NN + + F +
Sbjct: 123 VLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRD 182
Query: 496 LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQW 543
L L+L+NN + V + + I + LH N C C + W
Sbjct: 183 LEILTLNNNNISRILVTS-FNHMPKIRTLRLHSNHLYCDCHLAWLSDW 229
Score = 70.1 bits (170), Expect = 7e-12
Identities = 42/123 (34%), Positives = 69/123 (56%), Gaps = 3/123 (2%)
Query: 424 DLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLL 483
D+ LY++ N+L + RE + L++L +++ N+I ++ TF+ M L LIL+ N L
Sbjct: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
Query: 484 RSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQ 542
R +PV F G+ SL L+LH N +P G + LTS+ + L NP C C++ +
Sbjct: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVP-EGSFNDLTSLSHLALGTNPLHCDCSLRWLSE 870
Query: 543 WAE 545
W +
Sbjct: 871 WVK 873
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 8/143 (5%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C + C+N+ + +L PK +V EL+L N + ++ + ++
Sbjct: 725 CPEQCTCMETV-----VRCSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRE-LSALRH 776
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L L+DL NN+I+ + N TF N+ L L + N L + F GL++L L + N I
Sbjct: 777 LTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDIS 836
Query: 461 LILPGTFNAMPKLRILILNNNLL 483
+ G+FN + L L L N L
Sbjct: 837 SVPEGSFNDLTSLSHLALGTNPL 859
Score = 56.6 bits (135), Expect = 8e-08
Identities = 69/271 (25%), Positives = 95/271 (35%), Gaps = 66/271 (24%)
Query: 24 CKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYN 83
C E+ C+C E V C KG +L R L+L GN LT
Sbjct: 725 CPEQ-CTCMETV----VRCSNKGLRALPR--GMPKDVTELYLEGNHLTA----------- 766
Query: 84 AVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLR 143
VP L+ + + ++NN I TF + L L +N LR
Sbjct: 767 --------------VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLR 812
Query: 144 DIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPG 203
I AF L L VL L+ N IS++P F +
Sbjct: 813 CIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN------------------------DLTS 848
Query: 204 IAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPL 263
++ + L NP C C L L EW++ K I R C +P + + L TT
Sbjct: 849 LSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIAR--CSSPEPMADR-LLLTTPTHRFQC 905
Query: 264 KNRVDSSLPAPPAQEETFAPGPLPTPFKTNG 294
K VD ++ A L +P K NG
Sbjct: 906 KGPVDINIVAK-------CNACLSSPCKNNG 929
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 118 bits (295), Expect = 2e-26
Identities = 121/542 (22%), Positives = 212/542 (39%), Gaps = 121/542 (22%)
Query: 29 CSC-NEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSL 87
C+C N I VDC KG T + T + L N++ + P F+ + +
Sbjct: 277 CTCSNNI-----VDCRGKGLTEIPTNLPET--ITEIRLEQNTIKVIPPGAFSPYKKLRRI 329
Query: 88 HMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDP 147
+ NN + E+ P AF GL+ + L + NKI K F GL L+ L + N + +
Sbjct: 330 DLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRV 389
Query: 148 GAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEI 207
AFQDL+ L +L L DN + T+ F + I +
Sbjct: 390 DAFQDLHNLNLLSLYDNKLQTIAKGTF------------------------SPLRAIQTM 425
Query: 208 LLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRV 267
L NP+ C C L L ++L P R C +P RL K + + +
Sbjct: 426 HLAQNPFICDCHLKWLADYLHTNPIETSGAR--CTSPRRLANKRIGQ------------I 471
Query: 268 DSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIAT 327
S A+E+ F P G ED+ +K+ G+
Sbjct: 472 KSKKFRCSAKEQYFIP----------GTEDYR---------SKLSGD------------- 499
Query: 328 GSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKI 387
L CP C C+ G ++C+N+ ++ + + P+ + EL L +N+
Sbjct: 500 -------CFADLACPEKCRCE-----GTTVDCSNQKLNKIPEHIPQYT--AELRLNNNEF 545
Query: 388 HSIRKSH-FVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGL 446
+ + F L ++ NN I +E F+ + + + SN L+ + + F GL
Sbjct: 546 TVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGL 605
Query: 447 QNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYF 506
++L+ L + N I + +F + +R+L L +N + ++
Sbjct: 606 ESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTV-------------------- 645
Query: 507 MYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFR 566
G D L S+ ++L NP+ C+C + +W + ++ + +C+ P +F
Sbjct: 646 ----APGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRK--KRIVTGNPRCQKP--YFL 697
Query: 567 KD 568
K+
Sbjct: 698 KE 699
Score = 98.2 bits (243), Expect = 2e-20
Identities = 124/479 (25%), Positives = 197/479 (41%), Gaps = 82/479 (17%)
Query: 5 ILLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLF 64
+L L L A N CSC+ VDC S+ R ++ L
Sbjct: 8 MLSLSLGLVLAILNKVAPQACPAQCSCSGST----VDCHGLALRSVPRNIPRNTE--RLD 61
Query: 65 LHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQ 124
L+GN++TR+ +FA + L + N + I GAF L+ ++RL +N N ++ F +
Sbjct: 62 LNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPEL 121
Query: 125 TFLG------LD------------------DLEYLQADFNLLRDIDPGAFQDLNKLEVLI 160
FLG LD D++ LQ D+N + I+ GAF+ L LEVL
Sbjct: 122 LFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLT 181
Query: 161 LNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDL 220
LN+N I+ L F ++P +L+T L N C C L
Sbjct: 182 LNNNNITRLSVASFNHMP---------KLRT---------------FRLHSNNLYCDCHL 217
Query: 221 LSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEET 280
L +WL P+ L + C P+ L+G ++ E +++ V S + A +
Sbjct: 218 AWLSDWLRQRPRVGLYTQ--CMGPSHLRGHNVAEVQKREF------VCSGHQSFMAPSCS 269
Query: 281 FAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLP 340
P N + G T+IP N I T + +P
Sbjct: 270 VLHCPAACTCSNNIVDCRG------KGLTEIPTNLPETI-------TEIRLEQNTIKVIP 316
Query: 341 CPGGCSCDHIPGSGL-KMNCNNRNVSSLA-DLKPKLSNVQELFLRDNKIHSIRKSHFVDY 398
PG S P L +++ +N +S LA D L ++ L L NKI + KS F
Sbjct: 317 -PGAFS----PYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 399 KNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
+L LL L N I + + F++L +L L + N L T+++ F+ L+ ++ +++ N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 74.7 bits (182), Expect = 3e-13
Identities = 55/189 (29%), Positives = 86/189 (45%), Gaps = 32/189 (16%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP CSC SG ++C+ + S+ P+ N + L L N I I K+ F ++
Sbjct: 28 CPAQCSC-----SGSTVDCHGLALRSVPRNIPR--NTERLDLNGNNITRITKTDFAGLRH 80
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLD------------------------ 436
L +L L N I+T+E F++L +L L ++ N+L
Sbjct: 81 LRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQ 140
Query: 437 TLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-S 495
+ R+ F G +++ L ++YN I I G F A+ L +L LNNN + L V F +
Sbjct: 141 AIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPK 200
Query: 496 LSKLSLHNN 504
L LH+N
Sbjct: 201 LRTFRLHSN 209
Score = 69.3 bits (168), Expect = 1e-11
Identities = 45/143 (31%), Positives = 72/143 (50%), Gaps = 8/143 (5%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C + C+N+ + L P+ +V EL+L N+ + K +YK+
Sbjct: 727 CPTECTC-----LDTVVRCSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKE-LSNYKH 778
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L L+DL NN I+T+ N +F N+ L L + N L + F GL++L L++ N I
Sbjct: 779 LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDIS 838
Query: 461 LILPGTFNAMPKLRILILNNNLL 483
++ G FN + L L + N L
Sbjct: 839 VVPEGAFNDLSALSHLAIGANPL 861
Score = 68.9 bits (167), Expect = 1e-11
Identities = 97/417 (23%), Positives = 163/417 (39%), Gaps = 66/417 (15%)
Query: 24 CKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNE-FANFY 82
C EK C C EG VDC + + + L L+ N T L F
Sbjct: 506 CPEK-CRC---EGTT-VDCSNQKLNKIPEHIPQYTA--ELRLNNNEFTVLEATGIFKKLP 558
Query: 83 NAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLL 142
++ NN + +I GAF G V + + +N++++ + + F GL+ L+ L N +
Sbjct: 559 QLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRI 618
Query: 143 RDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIP 202
+ +F L+ + +L L DN I+T+ F + +
Sbjct: 619 TCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF------------------------DTLH 654
Query: 203 GIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDL-C 261
++ + L NP++C C L L EWL K + G C+ P L+ + + QD C
Sbjct: 655 SLSTLNLLANPFNCNCYLAWLGEWLRK--KRIVTGNPRCQKPYFLKEIPIQDVAIQDFTC 712
Query: 262 PLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTK--IPGNWQIKI 319
N +S P E L T + + + P P T+ + GN Q +
Sbjct: 713 DDGNDDNSCSPLSRCPTECTC---LDTVVRCSNKGLKVLPKGIPRDVTELYLDGN-QFTL 768
Query: 320 RPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLK-PKLSNVQ 378
P K L+N H+ ++ +N +S+L++ ++ +
Sbjct: 769 VP-----------KELSN---------YKHL----TLIDLSNNRISTLSNQSFSNMTQLL 804
Query: 379 ELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYL 435
L L N++ I F K+L LL L N+I+ V F +L L L + +N L
Sbjct: 805 TLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
Score = 68.2 bits (165), Expect = 3e-11
Identities = 60/236 (25%), Positives = 103/236 (43%), Gaps = 20/236 (8%)
Query: 334 PLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKS 393
P + L CP C+C S ++C + ++ + P+ + E+ L N I I
Sbjct: 266 PSCSVLHCPAACTC-----SNNIVDCRGKGLTEIPTNLPE--TITEIRLEQNTIKVIPPG 318
Query: 394 HFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLN 453
F YK L +DL NN I+ + + F+ L L L + N + L + F GL +L+ L
Sbjct: 319 AFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLL 378
Query: 454 VEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVA 512
+ N I + F + L +L L +N L+++ F+ + ++ + L N F
Sbjct: 379 LNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPF------ 432
Query: 513 GVLDQLTSIIQIDLHGNPWECS---CTIVPFKQWAERLGSEVLMSDLKCETPVNFF 565
+ D + LH NP E S CT P + +R+G ++ +C +F
Sbjct: 433 -ICDCHLKWLADYLHTNPIETSGARCT-SPRRLANKRIG-QIKSKKFRCSAKEQYF 485
Score = 58.5 bits (140), Expect = 2e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Query: 424 DLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLL 483
D+ LY+D N TL ++ + ++L +++ N I + +F+ M +L LIL+ N L
Sbjct: 755 DVTELYLDGNQF-TLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRL 813
Query: 484 RSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQ 542
R +P F G+ SL LSLH N +P G + L+++ + + NP C C +
Sbjct: 814 RCIPPRTFDGLKSLRLLSLHGNDISVVP-EGAFNDLSALSHLAIGANPLYCDCNMQWLSD 872
Query: 543 WAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQ------LYARISPTLTSHSKN 595
W + E ++ +C P K + + + Q + A+ +P L++ KN
Sbjct: 873 WVKSEYKEPGIA--RCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKN 929
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/227 (23%), Positives = 83/227 (36%), Gaps = 57/227 (25%)
Query: 29 CSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLH 88
C+C D V C KG L + L+L GN T L P E +N+ +
Sbjct: 731 CTCL----DTVVRCSNKGLKVLPK--GIPRDVTELYLDGNQFT-LVPKELSNYKH----- 778
Query: 89 MENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPG 148
+ + ++NN+I + Q+F + L L +N LR I P
Sbjct: 779 -------------------LTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPR 819
Query: 149 AFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEIL 208
F L L +L L+ N IS +P F + ++ +
Sbjct: 820 TFDGLKSLRLLSLHGNDISVVPEGAF------------------------NDLSALSHLA 855
Query: 209 LEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNET 255
+ NP C C++ L +W+++ K I R C P + K L T
Sbjct: 856 IGANPLYCDCNMQWLSDWVKSEYKEPGIAR--CAGPGEMADKLLLTT 900
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 108 bits (271), Expect = 1e-23
Identities = 135/520 (25%), Positives = 202/520 (38%), Gaps = 106/520 (20%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L L GN+L L P F +L++ +N L + AF GL V+ L +++N +
Sbjct: 139 LELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLA 198
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAF----QDLNKLEV-------------------- 158
+ GL L L N L+ + PG + L +LE+
Sbjct: 199 PEALAGLPALRRLSLHHNELQAL-PGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLR 257
Query: 159 -LILNDNLISTLPANVFQYVPITH-LDLRGNRLKTLPYEEVLEQIPG-IAEILLEDNPWD 215
L+L+ + L F + P H LDLRGN+L TLP Q PG + + L+ NP
Sbjct: 258 ELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPL----QGPGQLRRLRLQGNPLW 313
Query: 216 CTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPP 275
C C L EWL + + C+ P RL+G+ L+ DL P
Sbjct: 314 CGCQARPLLEWLA---RARVRSDGACQGPRRLRGEALDALRPWDL---------RCPGDA 361
Query: 276 AQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPL 335
AQEE + + A P + P G + PG + A+A
Sbjct: 362 AQEE-----------EELEERAVAGPRAPPRGPPRGPGEER-------AVA--------- 394
Query: 336 ANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHF 395
PCP C C +P S +C + ++ P S+ Q L LR N S+ ++ F
Sbjct: 395 ----PCPRACVC--VPESR-HSSCEGCGLQAVPRGFP--SDTQLLDLRRNHFPSVPRAAF 445
Query: 396 VDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVE 455
+L+ L L + IA +E L L +LY+ N L LS G L YL +E
Sbjct: 446 PGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLE 505
Query: 456 YN------------------------AIQLILPGTFNAMPKLRILILNNNLLRSLPVDVF 491
N A+ + PG LR + L+ N + + +
Sbjct: 506 RNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGAL 565
Query: 492 AGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
L KL L N +P G L+ L +++++ L GNP
Sbjct: 566 GPARELEKLHLDRNQLREVP-TGALEGLPALLELQLSGNP 604
Score = 82.0 bits (201), Expect = 2e-15
Identities = 66/215 (30%), Positives = 99/215 (46%), Gaps = 31/215 (14%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C CD+ S + C +N++ + D P+L+ Q L L+ N + I + F +
Sbjct: 33 CPQACICDN---SRRHVACRYQNLTEVPDAIPELT--QRLDLQGNLLKVIPAAAFQGVPH 87
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L LDL + + V F+ L L L + SN+L L +E GL +L L +E NA++
Sbjct: 88 LTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALE 147
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-------------------------S 495
+ PGTF A+ L L L +N L LP F G+ +
Sbjct: 148 ELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPA 207
Query: 496 LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNP 530
L +LSLH+N LP VL Q + +++L NP
Sbjct: 208 LRRLSLHHNELQALP-GPVLSQARGLARLELGHNP 241
Score = 69.7 bits (169), Expect = 9e-12
Identities = 53/193 (27%), Positives = 90/193 (46%), Gaps = 9/193 (4%)
Query: 61 YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS 120
+ L L N++ RL P + +++ N + E+ GA + +++LH++ N+++
Sbjct: 524 FSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLRE 583
Query: 121 FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNK-LEVLILNDNLISTLPANVFQYV-- 177
GL L LQ N LR + GAFQ + + L+ L LN + + + F +
Sbjct: 584 VPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGP 643
Query: 178 PITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIG 237
+ L L+ N+L+ LP L + + I L NP+ C C LL L WL + N +G
Sbjct: 644 GLQSLHLQKNQLRALP---ALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGL--NLRVG 698
Query: 238 RVVCEAPTRLQGK 250
C P +G+
Sbjct: 699 -ATCATPPNARGQ 710
Score = 65.9 bits (159), Expect = 1e-10
Identities = 61/214 (28%), Positives = 88/214 (41%), Gaps = 33/214 (15%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L +++ L L N + +R F L L+L +N + + F+ LL +RWL + N
Sbjct: 133 LGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHN 192
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTF-------------------------N 468
L L+ E AGL L L++ +N +Q LPG
Sbjct: 193 ALSVLAPEALAGLPALRRLSLHHNELQ-ALPGPVLSQARGLARLELGHNPLTYAGEEDGL 251
Query: 469 AMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLH 527
A+P LR L+L+ L++L FA L L L N LP QL ++ L
Sbjct: 252 ALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLR---RLRLQ 308
Query: 528 GNPWECSCTIVPFKQWAERLGSEVLMSDLKCETP 561
GNP C C P +W R + SD C+ P
Sbjct: 309 GNPLWCGCQARPLLEWLARAR---VRSDGACQGP 339
Score = 50.4 bits (119), Expect = 5e-06
Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 28/211 (13%)
Query: 27 KICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVS 86
+ C C + H CE G ++ R +Q L L N + F + VS
Sbjct: 398 RACVC--VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVS 453
Query: 87 LHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDID 146
LH+++ G+ E+ GA GL + L++++N++ G L YL + N +
Sbjct: 454 LHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVP 513
Query: 147 PGAFQDLNKLEVLILNDNLISTL-PANVFQYVPITHLDLRGNRLKTL------PYEEV-- 197
A + L L L L DN + L P ++ + + + L GNR+ + P E+
Sbjct: 514 GAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEK 573
Query: 198 ---------------LEQIPGIAEILLEDNP 213
LE +P + E+ L NP
Sbjct: 574 LHLDRNQLREVPTGALEGLPALLELQLSGNP 604
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 100 bits (250), Expect = 3e-21
Identities = 72/231 (31%), Positives = 112/231 (48%), Gaps = 26/231 (11%)
Query: 86 SLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDI 145
+LH+++N +H + AF + + L+++NN + + F GL L+ L N L +
Sbjct: 54 TLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSL 113
Query: 146 DPGAFQDLNKLEVLILNDNLISTLPANVFQ-YVPITHLDLRGNRLKTLPYEEVLEQIPGI 204
+ F L +L L L+ N IS LP ++ + + +T L ++ N+L+ L +LE +P +
Sbjct: 114 ESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLD-RALLESMPSV 172
Query: 205 AEILLEDNPWDCTCDLLSLKEWLEN-IPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPL 263
+LL+DN W C C LL LK WLE + K L ++CE+P +GKDL
Sbjct: 173 RLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDL----------- 221
Query: 264 KNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGN 314
L P E + P PLP P + Q PGSA + P N
Sbjct: 222 -------LRIP---HELYQPCPLPAPDPVSSQAQ--WPGSAHGVVLRPPEN 260
Score = 73.9 bits (180), Expect = 5e-13
Identities = 61/243 (25%), Positives = 115/243 (47%), Gaps = 34/243 (13%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C C S ++C+ + ++ + P + L L+DN+IH + F
Sbjct: 21 CPDKCYCQ---SSTNFVDCSQQGLAEIPSHLPP--QTRTLHLQDNQIHHLPAFAFRSVPW 75
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L+ L+L NN+ L L+ F GLQ+L+ LN+ N++
Sbjct: 76 LMTLNLSNNS------------------------LSNLAPGAFHGLQHLQVLNLTQNSLL 111
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDV-FAGVSLSKLSLHNNYFMYLPVAGVLDQLT 519
+ F+++P+LR L L++N + LP + +L+ L++ N L A +L+ +
Sbjct: 112 SLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRA-LLESMP 170
Query: 520 SIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSD-LKCETPVNFFRKDFMLLSND--E 576
S+ + L N W+C+C ++ K W E+ + ++D + CE+P + KD + + ++ +
Sbjct: 171 SVRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRIPHELYQ 230
Query: 577 ICP 579
CP
Sbjct: 231 PCP 233
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 99.4 bits (246), Expect = 1e-20
Identities = 67/239 (28%), Positives = 119/239 (49%), Gaps = 10/239 (4%)
Query: 356 KMNCNNRNVSSLA-DLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATV 414
++ +N ++S L + +L + L L N + + F NL L L +N+I+++
Sbjct: 255 RLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSL 314
Query: 415 ENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLR 474
+N F NL L+ L + N + +S F GL L L++ NA+Q + F + L+
Sbjct: 315 PDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQ 374
Query: 475 ILILNNNLLRSLPVDVFAGVS-LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWEC 533
+ L NN LR LP ++FA V+ L + L NN LP+ G+ D L + ++ L+ NPW C
Sbjct: 375 NISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRC 433
Query: 534 SCTIVPFKQW----AERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPT 588
I+P + W RLG++ + C +P N + ++++ + P ++ P+
Sbjct: 434 DSDILPLRNWLLLNQPRLGTDTVP---VCFSPANVRGQSLIIINVNVAVPSVHVPEVPS 489
Score = 90.9 bits (224), Expect = 4e-18
Identities = 60/196 (30%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
Query: 59 QFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKI 118
Q L L GNSL L F N L + +N + + F L+ ++ L ++ N+I
Sbjct: 276 QLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQI 335
Query: 119 KSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV- 177
F GL +L L N L+D+D F+ L L+ + L +N + LP N+F V
Sbjct: 336 SFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVN 395
Query: 178 PITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEW-LENIPKNALI 236
+ + L+ N+L+ LP + + + + E+ L DNPW C D+L L+ W L N P+
Sbjct: 396 GLMAIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTD 454
Query: 237 GRVVCEAPTRLQGKDL 252
VC +P ++G+ L
Sbjct: 455 TVPVCFSPANVRGQSL 470
Score = 70.5 bits (171), Expect = 5e-12
Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 10/187 (5%)
Query: 348 DHIPGSGLKMNCNNRNVSSLADLKPK----LSNVQELFLRDNKIHSIRKSHFVDYKNLIL 403
DH+ G K+N +SL + P+ L N+Q L L +N++ I F NL
Sbjct: 176 DHLVGL-TKLNLGK---NSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 231
Query: 404 LDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLIL 463
L L N I + F N +L+ LY+ +N++ L F L L L + N+++ +
Sbjct: 232 LALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELS 291
Query: 464 PGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSII 522
G F MP LR L L +N + SLP +VF+ + L L L N ++ G + LT +
Sbjct: 292 LGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFIS-PGAFNGLTELR 350
Query: 523 QIDLHGN 529
++ LH N
Sbjct: 351 ELSLHTN 357
Score = 68.6 bits (166), Expect = 2e-11
Identities = 65/229 (28%), Positives = 106/229 (46%), Gaps = 17/229 (7%)
Query: 310 KIPGNWQIKIRPTAAIATGSSRNKPLANS----LPCPGGCSCDHIPGSGLKMNCNNRNVS 365
+I N +I P A GS R LAN+ LP D + L N
Sbjct: 89 RIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSN------- 141
Query: 366 SLADLKP----KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKN 421
L ++P + SN++EL L N + I F L L+LG N++ + F++
Sbjct: 142 QLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQH 201
Query: 422 LLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNN 481
L +L+ L + N L + F GL NL+ L ++ N I L+ PG F+ L+ L L+NN
Sbjct: 202 LGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 261
Query: 482 LLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
+ LP +F + L++L+L N L + G+ + ++ ++ L+ N
Sbjct: 262 HISQLPPSIFMQLPQLNRLTLFGNSLKELSL-GIFGPMPNLRELWLYDN 309
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/121 (34%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Query: 70 LTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGL 129
+T L + F N ++L +E N L I PGAF L ++ L + NNK++ F GL
Sbjct: 71 ITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGL 130
Query: 130 DDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQY-VPITHLDLRGNR 188
D LE L N L I P F + L+ L L+ N + +P F + V +T L+L N
Sbjct: 131 DSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNS 190
Query: 189 L 189
L
Sbjct: 191 L 191
Score = 64.3 bits (155), Expect = 4e-10
Identities = 47/170 (27%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C ++ C + ++ P N L + + I + +S F++
Sbjct: 31 CPSECTCSRAS----QVECTGARIVAVPTPLPW--NAMSLQILNTHITELNESPFLNISA 84
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
LI L + N ++ + F+NL LR+L + +N L L F GL +LE L + N +
Sbjct: 85 LIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLL 144
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDVFAG-VSLSKLSLHNNYFMYL 509
I P F+ L+ L L+ N L +P F V L+KL+L N ++
Sbjct: 145 QIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHI 194
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 2/132 (1%)
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
+NA+SL + N + E+ FL + + L I N++ F L L YL N
Sbjct: 59 WNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNK 118
Query: 142 LRDIDPGAFQDLNKLEVLILNDN-LISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQ 200
L+ + G FQ L+ LE L+L+ N L+ PA+ Q + L L GN L+ +P + +
Sbjct: 119 LQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP-DGAFDH 177
Query: 201 IPGIAEILLEDN 212
+ G+ ++ L N
Sbjct: 178 LVGLTKLNLGKN 189
Score = 56.6 bits (135), Expect = 8e-08
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 2/151 (1%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L + N L+R+ P F N + L + NN L + G F GL ++ L +++N++ +
Sbjct: 88 LRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQ 147
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITH 181
F +L+ LQ N L I GAF L L L L N ++ + VFQ++ +
Sbjct: 148 PAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQV 207
Query: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
L L NRL +P + + + E+ L+ N
Sbjct: 208 LRLYENRLTDIPM-GTFDGLVNLQELALQQN 237
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 99.4 bits (246), Expect = 1e-20
Identities = 67/239 (28%), Positives = 119/239 (49%), Gaps = 10/239 (4%)
Query: 356 KMNCNNRNVSSLA-DLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATV 414
++ +N ++S L + +L + L L N + + F NL L L +N+I+++
Sbjct: 249 RLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSL 308
Query: 415 ENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLR 474
+N F NL L+ L + N + +S F GL L L++ NA+Q + F + L+
Sbjct: 309 PDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQ 368
Query: 475 ILILNNNLLRSLPVDVFAGVS-LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWEC 533
+ L NN LR LP ++FA V+ L + L NN LP+ G+ D L + ++ L+ NPW C
Sbjct: 369 NISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRC 427
Query: 534 SCTIVPFKQW----AERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPT 588
I+P + W RLG++ + C +P N + ++++ + P ++ P+
Sbjct: 428 DSDILPLRNWLLLNQPRLGTDTVP---VCFSPANVRGQSLIIINVNVAVPSVHVPEVPS 483
Score = 90.9 bits (224), Expect = 4e-18
Identities = 60/196 (30%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
Query: 59 QFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKI 118
Q L L GNSL L F N L + +N + + F L+ ++ L ++ N+I
Sbjct: 270 QLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQI 329
Query: 119 KSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV- 177
F GL +L L N L+D+D F+ L L+ + L +N + LP N+F V
Sbjct: 330 SFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVN 389
Query: 178 PITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEW-LENIPKNALI 236
+ + L+ N+L+ LP + + + + E+ L DNPW C D+L L+ W L N P+
Sbjct: 390 GLMAIQLQNNQLENLPL-GIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTD 448
Query: 237 GRVVCEAPTRLQGKDL 252
VC +P ++G+ L
Sbjct: 449 TVPVCFSPANVRGQSL 464
Score = 70.5 bits (171), Expect = 5e-12
Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 10/187 (5%)
Query: 348 DHIPGSGLKMNCNNRNVSSLADLKPK----LSNVQELFLRDNKIHSIRKSHFVDYKNLIL 403
DH+ G K+N +SL + P+ L N+Q L L +N++ I F NL
Sbjct: 170 DHLVGL-TKLNLGK---NSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 225
Query: 404 LDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLIL 463
L L N I + F N +L+ LY+ +N++ L F L L L + N+++ +
Sbjct: 226 LALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELS 285
Query: 464 PGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSII 522
G F MP LR L L +N + SLP +VF+ + L L L N ++ G + LT +
Sbjct: 286 LGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFIS-PGAFNGLTELR 344
Query: 523 QIDLHGN 529
++ LH N
Sbjct: 345 ELSLHTN 351
Score = 68.6 bits (166), Expect = 2e-11
Identities = 65/229 (28%), Positives = 106/229 (46%), Gaps = 17/229 (7%)
Query: 310 KIPGNWQIKIRPTAAIATGSSRNKPLANS----LPCPGGCSCDHIPGSGLKMNCNNRNVS 365
+I N +I P A GS R LAN+ LP D + L N
Sbjct: 83 RIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSN------- 135
Query: 366 SLADLKP----KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKN 421
L ++P + SN++EL L N + I F L L+LG N++ + F++
Sbjct: 136 QLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQH 195
Query: 422 LLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNN 481
L +L+ L + N L + F GL NL+ L ++ N I L+ PG F+ L+ L L+NN
Sbjct: 196 LGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNN 255
Query: 482 LLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
+ LP +F + L++L+L N L + G+ + ++ ++ L+ N
Sbjct: 256 HISQLPPSIFMQLPQLNRLTLFGNSLKELSL-GIFGPMPNLRELWLYDN 303
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/121 (34%), Positives = 60/121 (49%), Gaps = 1/121 (0%)
Query: 70 LTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGL 129
+T L + F N ++L +E N L I PGAF L ++ L + NNK++ F GL
Sbjct: 65 ITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGL 124
Query: 130 DDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQY-VPITHLDLRGNR 188
D LE L N L I P F + L+ L L+ N + +P F + V +T L+L N
Sbjct: 125 DSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNS 184
Query: 189 L 189
L
Sbjct: 185 L 185
Score = 64.3 bits (155), Expect = 4e-10
Identities = 47/170 (27%), Positives = 78/170 (45%), Gaps = 7/170 (4%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C ++ C + ++ P N L + + I + +S F++
Sbjct: 25 CPSECTCSRAS----QVECTGARIVAVPTPLPW--NAMSLQILNTHITELNESPFLNISA 78
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
LI L + N ++ + F+NL LR+L + +N L L F GL +LE L + N +
Sbjct: 79 LIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLL 138
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDVFAG-VSLSKLSLHNNYFMYL 509
I P F+ L+ L L+ N L +P F V L+KL+L N ++
Sbjct: 139 QIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHI 188
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 2/132 (1%)
Query: 82 YNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNL 141
+NA+SL + N + E+ FL + + L I N++ F L L YL N
Sbjct: 53 WNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNK 112
Query: 142 LRDIDPGAFQDLNKLEVLILNDN-LISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQ 200
L+ + G FQ L+ LE L+L+ N L+ PA+ Q + L L GN L+ +P + +
Sbjct: 113 LQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP-DGAFDH 171
Query: 201 IPGIAEILLEDN 212
+ G+ ++ L N
Sbjct: 172 LVGLTKLNLGKN 183
Score = 56.6 bits (135), Expect = 8e-08
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 2/151 (1%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L + N L+R+ P F N + L + NN L + G F GL ++ L +++N++ +
Sbjct: 82 LRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQ 141
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITH 181
F +L+ LQ N L I GAF L L L L N ++ + VFQ++ +
Sbjct: 142 PAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQV 201
Query: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
L L NRL +P + + + E+ L+ N
Sbjct: 202 LRLYENRLTDIPM-GTFDGLVNLQELALQQN 231
>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
Length = 473
Score = 94.4 bits (233), Expect = 3e-19
Identities = 76/281 (27%), Positives = 116/281 (41%), Gaps = 54/281 (19%)
Query: 29 CSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLH 88
C C E + C ++G ++ SQ +FLHGN ++ + F N L
Sbjct: 31 CVCYN-EPKVTTSCPQQGLQAVPVGIPAASQ--RIFLHGNRISHVPAASFRACRNLTILW 87
Query: 89 MENNGLHEIVPGAFLGLQLVKRLHINNN-KIKSFRKQTFLGLDDLEYLQADFNLLRDIDP 147
+ +N L I AF GL L+++L +++N +++S TF GL L L D L+++ P
Sbjct: 88 LHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGP 147
Query: 148 GAFQDLNKLEVLILNDNLISTLPANVFQYV-PITHLDLRGNRLKTLPYE----------- 195
G F+ L L+ L L DN + LP + F+ + +THL L GNR+ ++P
Sbjct: 148 GLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRL 207
Query: 196 ------------------------------------EVLEQIPGIAEILLEDNPWDCTCD 219
E L + + + L DNPW C C
Sbjct: 208 LLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCR 267
Query: 220 LLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDL 260
L WL+ ++ V C P RL G+DL DL
Sbjct: 268 ARPLWAWLQKFRGSS--SEVPCSLPQRLAGRDLKRLAANDL 306
Score = 80.1 bits (196), Expect = 6e-15
Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 57/288 (19%)
Query: 340 PCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYK 399
PCPG C C + P + +C + + ++ P S Q +FL N+I + + F +
Sbjct: 26 PCPGACVCYNEPK--VTTSCPQQGLQAVPVGIPAAS--QRIFLHGNRISHVPAASFRACR 81
Query: 400 NLILLDLGNNNIA-------------------------TVENNTFKNLLDLRWLYMDSNY 434
NL +L L +N +A +V+ TF L L L++D
Sbjct: 82 NLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCG 141
Query: 435 LDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV 494
L L F GL L+YL ++ NA+Q + TF + L L L+ N + S+P F G+
Sbjct: 142 LQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGL 201
Query: 495 -SLSKLSLHNNYFMY------------------------LPVAGVLDQLTSIIQIDLHGN 529
SL +L LH N + LP L L ++ + L+ N
Sbjct: 202 HSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTE-ALAPLRALQYLRLNDN 260
Query: 530 PWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEI 577
PW C C P W ++ S++ C P +D L+ +++
Sbjct: 261 PWVCDCRARPLWAWLQKFRGS--SSEVPCSLPQRLAGRDLKRLAANDL 306
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 94.0 bits (232), Expect = 4e-19
Identities = 77/285 (27%), Positives = 123/285 (43%), Gaps = 26/285 (9%)
Query: 6 LLLETSLCFAAGNVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFL 65
LL+ ++ G C + C+C V C + TS+ P + + L
Sbjct: 11 LLVSFAVICLVATPGGKACPRR-CACYM---PTEVHCTFRYLTSIPDSIPPNVE--RINL 64
Query: 66 HGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQT 125
NSL RL +F+ L + +NG+H I F LQ ++ L ++ NK++ +K T
Sbjct: 65 GYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDT 124
Query: 126 FLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPAN---------VFQY 176
F GL L L D N + I+P F LN L ++ L N ++ L + +F+
Sbjct: 125 FYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKI 184
Query: 177 VPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIP----- 231
I L L N L +LP +E++ +P + + L NPW C C L L +W++ P
Sbjct: 185 SFIKFLYLSDNFLTSLP-QEMVSYMPDLDSLYLHGNPWTCDCHLKWLSDWIQEKPDVIKC 243
Query: 232 -----KNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSL 271
++ +C P +GK L + K +DSSL
Sbjct: 244 KKDRSPSSAQQCPLCMNPRTSKGKPLAMVSAAAFQCAKPTIDSSL 288
Score = 93.2 bits (230), Expect = 7e-19
Identities = 63/214 (29%), Positives = 107/214 (50%), Gaps = 16/214 (7%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C+C ++P +++C R ++S+ D P NV+ + L N + + ++ F
Sbjct: 29 CPRRCAC-YMP---TEVHCTFRYLTSIPDSIPP--NVERINLGYNSLVRLMETDFSGLTK 82
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L LL L +N I T+ + TF +L L+ L M N + L ++ F GL++L L++++N I+
Sbjct: 83 LELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIE 142
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS---------LSKLSLHNNYFMYLPV 511
I P F + LR++ L N L L D F +S + L L +N+ LP
Sbjct: 143 FINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKISFIKFLYLSDNFLTSLP- 201
Query: 512 AGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAE 545
++ + + + LHGNPW C C + W +
Sbjct: 202 QEMVSYMPDLDSLYLHGNPWTCDCHLKWLSDWIQ 235
>gi|198041768 synleurin [Homo sapiens]
Length = 622
Score = 93.6 bits (231), Expect = 6e-19
Identities = 58/208 (27%), Positives = 110/208 (52%), Gaps = 7/208 (3%)
Query: 357 MNCNNRNVSSLADLK-PKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVE 415
++ +N N+ +++ L N+ L+L N + + + F K+L L L +N I ++
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 416 NNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRI 475
FK L +L +L + ++ + ++R+ F+G+ NL++L + +N ++ + TF+ + L
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIY 304
Query: 476 LILNNNLLRSLPVDVF--AGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWEC 533
L L+ N + S+ D F G SL L+L N L VL L+S+I + + NPWEC
Sbjct: 305 LKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALH-PRVLKPLSSLIHLQANSNPWEC 363
Query: 534 SCTIVPFKQWAERLGSEVLMSDLKCETP 561
+C ++ + W L S + ++ C+ P
Sbjct: 364 NCKLLGLRDW---LASSAITLNIYCQNP 388
Score = 86.7 bits (213), Expect = 7e-17
Identities = 55/215 (25%), Positives = 105/215 (48%), Gaps = 28/215 (13%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L L N++ R+ + F + N L++ +N L ++ AF L+ ++RL +++N I++ +
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITH 181
F GL +LEYL + +R++ F +N L+ LIL+ N + L ++ F + + +
Sbjct: 245 PFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIY 304
Query: 182 LDLRGNRL------------------------KTLPYEEVLEQIPGIAEILLEDNPWDCT 217
L L NR+ T + VL+ + + + NPW+C
Sbjct: 305 LKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECN 364
Query: 218 CDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDL 252
C LL L++WL + +A+ + C+ P ++G+ L
Sbjct: 365 CKLLGLRDWLAS---SAITLNIYCQNPPSMRGRAL 396
Score = 75.1 bits (183), Expect = 2e-13
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 27/220 (12%)
Query: 344 GCSCDHIPGSGLKMNCNNRNVSSLADLKPK----------------------LSNVQELF 381
GCS +G ++NC N +SS+ P+ L ++ L+
Sbjct: 31 GCSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALY 90
Query: 382 LRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSRE 441
L ++ I + FV ++L L L NN I ++ FK LL+LR LY+ N + + R
Sbjct: 91 LDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRG 150
Query: 442 KFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILIL-NNNLLRSLPVDVFAGVSLSKLS 500
F L +++YLN++ N + ++ GTF M LRIL L NNN+LR +L+ L
Sbjct: 151 VFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLY 210
Query: 501 LHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPF 540
L +N +P + + L S+ ++ L NP E I PF
Sbjct: 211 LGSNNLTKVP-SNAFEVLKSLRRLSLSHNPIE---AIQPF 246
Score = 67.4 bits (163), Expect = 4e-11
Identities = 46/174 (26%), Positives = 88/174 (50%), Gaps = 4/174 (2%)
Query: 40 VDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVP 99
++C G +S+ + ++ F L+L GN+++ + +E ++ V+L+++N+ + + P
Sbjct: 44 INCRNLGLSSIPKNFPESTVF--LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYP 101
Query: 100 GAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVL 159
AF+ L+ + L +NNN IK F GL +L L +N + + G F DL ++ L
Sbjct: 102 KAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYL 161
Query: 160 ILNDNLISTLPANVF-QYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
L N ++ L + F V + LDL N + + E + + +A + L N
Sbjct: 162 NLQRNRLTVLGSGTFVGMVALRILDLSNNNILRIS-ESGFQHLENLACLYLGSN 214
Score = 61.2 bits (147), Expect = 3e-09
Identities = 38/133 (28%), Positives = 64/133 (48%), Gaps = 1/133 (0%)
Query: 61 YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS 120
Y LFL+ N + RL P F N +L+++ N + + G F L V+ L++ N++
Sbjct: 111 YFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTV 170
Query: 121 FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PI 179
TF+G+ L L N + I FQ L L L L N ++ +P+N F+ + +
Sbjct: 171 LGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSL 230
Query: 180 THLDLRGNRLKTL 192
L L N ++ +
Sbjct: 231 RRLSLSHNPIEAI 243
Score = 58.2 bits (139), Expect = 3e-08
Identities = 38/152 (25%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L+L +++ ++P F + L + NN + + PG F GL ++ L++ N++
Sbjct: 89 LYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVP 148
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP-ITH 181
+ F L ++YL N L + G F + L +L L++N I + + FQ++ +
Sbjct: 149 RGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLAC 208
Query: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNP 213
L L N L +P E + + + L NP
Sbjct: 209 LYLGSNNLTKVP-SNAFEVLKSLRRLSLSHNP 239
>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
Length = 420
Score = 92.0 bits (227), Expect = 2e-18
Identities = 74/241 (30%), Positives = 116/241 (48%), Gaps = 18/241 (7%)
Query: 374 LSNVQELFLRDNK-IHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDS 432
L ++EL L DN+ + S+ F + L L L ++++ N F+ L+ L++LY+
Sbjct: 105 LQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQE 164
Query: 433 NYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFA 492
N L L + FA L NL +L + N ++L+ F + L L+L+ N L+ + F
Sbjct: 165 NSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFR 224
Query: 493 GVS-LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEV 551
G+S L+ L L NN LP + D L S+ + L+ NPW C C P W +R + V
Sbjct: 225 GLSRLTILYLFNNSLASLPGEALAD-LPSLEFLRLNANPWACDCRARPLWAWFQR--ARV 281
Query: 552 LMSDLKCETPVNFFRKDFMLL--SNDEICPQLYARISPTL-------TSHSKNSTGLAET 602
SD+ C TP +D L ++ + CP +PT S S + G+AE
Sbjct: 282 SSSDVTCATPPERQGRDLRALREADFQACPP----AAPTRPGSRARGNSSSNHLYGVAEA 337
Query: 603 G 603
G
Sbjct: 338 G 338
Score = 83.2 bits (204), Expect = 8e-16
Identities = 70/254 (27%), Positives = 104/254 (40%), Gaps = 38/254 (14%)
Query: 58 SQFYHLFLHGNSLTRLFPNEFANFYNAVSLHM-ENNGLHEIVPGAFLGLQLVKRLHINNN 116
S L+L N+L+ ++P F + L + +N L + P F GL+ ++ LH+
Sbjct: 82 SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRC 141
Query: 117 KIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQY 176
++ S F GL L+YL N L + F DL L L L+ N + L +VF+
Sbjct: 142 QLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRG 201
Query: 177 V-PITHLDLRGNRLK-------------TLPY----------EEVLEQIPGIAEILLEDN 212
+ + L L GNRL+ T+ Y E L +P + + L N
Sbjct: 202 LGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Query: 213 PWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDL--CPLKNRVDSS 270
PW C C L W + ++ V C P QG+DL E D CP
Sbjct: 262 PWACDCRARPLWAWFQRARVSS--SDVTCATPPERQGRDLRALREADFQACP-------- 311
Query: 271 LPAPPAQEETFAPG 284
PA P + + A G
Sbjct: 312 -PAAPTRPGSRARG 324
Score = 44.3 bits (103), Expect = 4e-04
Identities = 29/89 (32%), Positives = 44/89 (49%)
Query: 369 DLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWL 428
DL L+N+ LFL N++ + + F +L L L N + V F+ L L L
Sbjct: 173 DLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTIL 232
Query: 429 YMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
Y+ +N L +L E A L +LE+L + N
Sbjct: 233 YLFNNSLASLPGEALADLPSLEFLRLNAN 261
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 89.0 bits (219), Expect = 1e-17
Identities = 61/215 (28%), Positives = 105/215 (48%), Gaps = 16/215 (7%)
Query: 338 SLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVD 397
+L CP C+C ++P +++C R+++S+ K +V+ + L N I ++ ++ F
Sbjct: 24 ALACPHPCAC-YVPS---EVHCTFRSLASVPAGIAK--HVERINLGFNSIQALSETSFAG 77
Query: 398 YKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYN 457
L LL + N I ++ + ++L L+ N L ++ + GL NL L++++N
Sbjct: 78 LTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHN 137
Query: 458 AIQLILPGTFNAMPKLRILILNNNLLRSLP---------VDVFAGVSLSKLSLHNNYFMY 508
I+ I P FN + LR+L L NLL L +D F ++ L L N
Sbjct: 138 KIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLSTIRHLYLAENMVRT 197
Query: 509 LPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQW 543
LP A +L + + + L GNPW C C + F +W
Sbjct: 198 LP-ASMLRNMPLLENLYLQGNPWTCDCEMRWFLEW 231
Score = 79.0 bits (193), Expect = 1e-14
Identities = 54/192 (28%), Positives = 81/192 (42%), Gaps = 20/192 (10%)
Query: 39 HVDCEKKGFTSLQRFT----APTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGL 94
HV+ GF S+Q + A ++ L +HGN + + + + N L
Sbjct: 56 HVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKL 115
Query: 95 HEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLN 154
I GL + RLHI++NKI+ Q F GL L L + NLL + P F
Sbjct: 116 RVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFT 175
Query: 155 KLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPW 214
L+ F+ I HL L N ++TLP +L +P + + L+ NPW
Sbjct: 176 FLD---------------YFRLSTIRHLYLAENMVRTLP-ASMLRNMPLLENLYLQGNPW 219
Query: 215 DCTCDLLSLKEW 226
C C++ EW
Sbjct: 220 TCDCEMRWFLEW 231
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 25/221 (11%)
Query: 50 LQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVK 109
L+ A Q L L N + + P F N +L + NN + I GAF L+ +K
Sbjct: 54 LEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLK 113
Query: 110 RLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTL 169
L++ N+I+S +Q F GL LE L FN + +DP +FQ L KLE L L++N I+ L
Sbjct: 114 YLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHL 173
Query: 170 PANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLEN 229
F + + + + L+ N C C++L L + L+
Sbjct: 174 VPGTFNH------------------------LESMKRLRLDSNTLHCDCEILWLADLLKT 209
Query: 230 IPKNA-LIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDS 269
++ +CE P R+QG+ + T ++L + R+ S
Sbjct: 210 YAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPRITS 250
Score = 79.7 bits (195), Expect = 8e-15
Identities = 54/198 (27%), Positives = 91/198 (45%), Gaps = 32/198 (16%)
Query: 341 CPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKN 400
CP C C + C + + ++ + P+ S + LR N+I I+ F +N
Sbjct: 36 CPSRCLCFRTT-----VRCMHLLLEAVPAVAPQTSILD---LRFNRIREIQPGAFRRLRN 87
Query: 401 LILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQ 460
L L L NN I + + F++L +L++LY+ N + ++ R+ F GL +LE L + +N I+
Sbjct: 88 LNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIE 147
Query: 461 LILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTS 520
+ P +F +PKL L L+NN + L V G + L S
Sbjct: 148 TLDPDSFQHLPKLERLFLHNNRITHL------------------------VPGTFNHLES 183
Query: 521 IIQIDLHGNPWECSCTIV 538
+ ++ L N C C I+
Sbjct: 184 MKRLRLDSNTLHCDCEIL 201
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 88.2 bits (217), Expect = 2e-17
Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 3/203 (1%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L+L N++T L + FA+ N L ++ N L + G F + L + +N++++
Sbjct: 246 LWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVA 305
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYV-PITH 181
+ TF L +L L +N + + G F+DL +L L L N ++ L +FQ + +
Sbjct: 306 EGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLEL 365
Query: 182 LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVC 241
L L N+L TLP E + + + + L NPW C C L L WL+ L + C
Sbjct: 366 LSLSKNQLTTLP-EGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYC 424
Query: 242 EAPTRLQGKDLNETTEQDL-CPL 263
P L+G+ + E+ L CP+
Sbjct: 425 AGPAYLKGQVVPALNEKQLVCPV 447
Score = 82.0 bits (201), Expect = 2e-15
Identities = 65/214 (30%), Positives = 93/214 (43%), Gaps = 26/214 (12%)
Query: 373 KLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNL-----LDLRW 427
KL ++QELFL N I + F L L L N I + + F +L L L+W
Sbjct: 215 KLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQW 274
Query: 428 -------------------LYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFN 468
L + N L+T++ FA L NL L + YNAI + G F
Sbjct: 275 NMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFR 334
Query: 469 AMPKLRILILNNNLLRSLPVDVFAGVS-LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLH 527
+ +L L L +N L +L +F +S L LSL N LP G+ D ++ + LH
Sbjct: 335 DLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP-EGIFDTNYNLFNLALH 393
Query: 528 GNPWECSCTIVPFKQWAERLGSEVLMSDLKCETP 561
GNPW+C C + W ++ +L C P
Sbjct: 394 GNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGP 427
Score = 60.1 bits (144), Expect = 7e-09
Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 19/208 (9%)
Query: 340 PCPGGCSC---------DHIPGSGLKMNCNNRNV----SSLADLKPKL----SNVQELFL 382
PCP GC C + + L + +N+ +S L+ + N+ ++
Sbjct: 21 PCPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVF 80
Query: 383 RDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREK 442
+ ++ R F L L++ ++ + N F NL L L ++ N L+ L
Sbjct: 81 LNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGL 140
Query: 443 FAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSL 501
F L LE L+++ N +Q + F + L+ L L NLL LP ++F + SL L L
Sbjct: 141 FQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKL 200
Query: 502 HNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
NN LP GV +L S+ ++ L N
Sbjct: 201 SNNALSGLP-QGVFGKLGSLQELFLDSN 227
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/147 (31%), Positives = 66/147 (44%), Gaps = 6/147 (4%)
Query: 69 SLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLG 128
S T L F + N + N L + P AF GL ++ L + + + F
Sbjct: 60 SFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSN 119
Query: 129 LDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH---LDLR 185
L L L +FN+L + G FQ L LE L L N + LP +FQ P+TH L+L
Sbjct: 120 LTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQ--PLTHLKTLNLA 177
Query: 186 GNRLKTLPYEEVLEQIPGIAEILLEDN 212
N L LP EE+ + + + L +N
Sbjct: 178 QNLLAQLP-EELFHPLTSLQTLKLSNN 203
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 3/179 (1%)
Query: 356 KMNCNNRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATV 414
K+ N + +L + L L+ ++ L L+ N++ ++ + F +L L+L N +A +
Sbjct: 125 KLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQL 184
Query: 415 ENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLR 474
F L L+ L + +N L L + F L +L+ L ++ N I + P F+ + L
Sbjct: 185 PEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLE 244
Query: 475 ILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWE 532
L L N + LP+ +FA + +L+ LSL N LP AG+ ++ + L N E
Sbjct: 245 RLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLP-AGLFAHTPCLVGLSLTHNQLE 302
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/147 (28%), Positives = 70/147 (47%), Gaps = 2/147 (1%)
Query: 67 GNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTF 126
G+S L N F+N + L + N L + G F L ++ LH+ N++++ ++ F
Sbjct: 106 GSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLF 165
Query: 127 LGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF-QYVPITHLDLR 185
L L+ L NLL + F L L+ L L++N +S LP VF + + L L
Sbjct: 166 QPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLD 225
Query: 186 GNRLKTLPYEEVLEQIPGIAEILLEDN 212
N + LP +V Q+ + + L+ N
Sbjct: 226 SNNISELP-PQVFSQLFCLERLWLQRN 251
Score = 54.7 bits (130), Expect = 3e-07
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 2/157 (1%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L +++L + + ++ + F + +L L L N + + F++L L L++ N
Sbjct: 96 LPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGN 155
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
L L R F L +L+ LN+ N + + F+ + L+ L L+NN L LP VF
Sbjct: 156 QLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGK 215
Query: 494 V-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
+ SL +L L +N LP V QL + ++ L N
Sbjct: 216 LGSLQELFLDSNNISELP-PQVFSQLFCLERLWLQRN 251
Score = 53.5 bits (127), Expect = 6e-07
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 2/163 (1%)
Query: 51 QRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKR 110
+R P + L L N L +L F + +L + NN L + G F L ++
Sbjct: 162 RRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQE 221
Query: 111 LHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLP 170
L +++N I Q F L LE L N + + F L L L L N++ LP
Sbjct: 222 LFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLP 281
Query: 171 ANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDN 212
A +F + P + L L N+L+T+ E + + ++L N
Sbjct: 282 AGLFAHTPCLVGLSLTHNQLETVA-EGTFAHLSNLRSLMLSYN 323
>gi|225579152 insulin-like growth factor binding protein, acid
labile subunit isoform 1 precursor [Homo sapiens]
Length = 643
Score = 87.8 bits (216), Expect = 3e-17
Identities = 69/238 (28%), Positives = 100/238 (42%), Gaps = 42/238 (17%)
Query: 65 LHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQ 124
L GN L L F SLH+E + L I P F GL ++RL + +N + +Q
Sbjct: 407 LSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQ 466
Query: 125 TFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH--- 181
+ GL +L L N L + FQ L KLE L+L+ N ++ LPA+ P+
Sbjct: 467 SLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALG--PLQRAFW 524
Query: 182 LDLRGNRLKTLP-------------------YEEVLEQIPGIAEILLEDNPWDCTCDLLS 222
LD+ NRL+ LP Q PG+ + LE NPWDC C L +
Sbjct: 525 LDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGLERLWLEGNPWDCGCPLKA 584
Query: 223 LKEW-LEN-----------------IPKNALIGRVVCEAPTRLQGKDLNETTEQDLCP 262
L+++ L+N P + C +P + G DL + +E P
Sbjct: 585 LRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAP 642
Score = 70.9 bits (172), Expect = 4e-12
Identities = 57/168 (33%), Positives = 82/168 (48%), Gaps = 6/168 (3%)
Query: 367 LADLKPKL----SNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNL 422
LA L+P L + ++EL L N + +I+ + FV L L L N IA V F L
Sbjct: 244 LAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGL 303
Query: 423 LDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNL 482
LRWL + N + L + F GL L L + +NAI + P TF + L L L +N
Sbjct: 304 KALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNR 363
Query: 483 LRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
+R L F G+ L L+L +N + AG LT++ ++L GN
Sbjct: 364 IRQLAERSFEGLGQLEVLTLDHNQLQEVK-AGAFLGLTNVAVMNLSGN 410
Score = 68.9 bits (167), Expect = 1e-11
Identities = 59/198 (29%), Positives = 90/198 (45%), Gaps = 8/198 (4%)
Query: 1 MLLWILLLETSLCFA----AGNVTGDVCKEK-ICSCNEIEGDLHVDCEKKGFTSLQRFTA 55
+L W+ L SL A G G C +CS ++ +L V C + T L
Sbjct: 52 LLSWVALGPRSLEGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVP 111
Query: 56 PTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINN 115
+Q L+L GN+L+ + P F N + L+++ L + P A LGL+ + LH+
Sbjct: 112 GGTQA--LWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLER 169
Query: 116 NKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQ 175
N+++S TF L L N L ++ G F+ L L L L N ++ LP F+
Sbjct: 170 NQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFR 229
Query: 176 YV-PITHLDLRGNRLKTL 192
+ + L L GNRL L
Sbjct: 230 GLGSLRELVLAGNRLAYL 247
Score = 67.0 bits (162), Expect = 6e-11
Identities = 43/144 (29%), Positives = 77/144 (53%), Gaps = 1/144 (0%)
Query: 368 ADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRW 427
A++ +L +Q+L+L N I ++ F+ K L LDL +N +A + +TF LL LR
Sbjct: 273 ANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRV 332
Query: 428 LYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLP 487
L + N + +L F L LE L + +N I+ + +F + +L +L L++N L+ +
Sbjct: 333 LRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVK 392
Query: 488 VDVFAGV-SLSKLSLHNNYFMYLP 510
F G+ +++ ++L N LP
Sbjct: 393 AGAFLGLTNVAVMNLSGNCLRNLP 416
Score = 65.9 bits (159), Expect = 1e-10
Identities = 44/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L ++ L L N++ + + F L +L L +N IA++ TFK+L L L + N
Sbjct: 303 LKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHN 362
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
+ L+ F GL LE L +++N +Q + G F + + ++ L+ N LR+LP VF G
Sbjct: 363 RIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRG 422
Query: 494 VSLSKL-SLH 502
L KL SLH
Sbjct: 423 --LGKLHSLH 430
Score = 65.1 bits (157), Expect = 2e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 360 NNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
+NR L D P L ++ L L N I S+R F D L L LG+N I + +F
Sbjct: 313 HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF 372
Query: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
+ L L L +D N L + F GL N+ +N+ N ++ + F + KL L L
Sbjct: 373 EGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLE 432
Query: 480 NNLLRSLPVDVFAGVS-LSKLSLHNNYFMYLPVAGVLDQ----LTSIIQIDLHGN 529
+ L + F G+S L +L L +N + G+ +Q L ++++DL N
Sbjct: 433 GSCLGRIRPHTFTGLSGLRRLFLKDN-----GLVGIEEQSLWGLAELLELDLTSN 482
Score = 63.2 bits (152), Expect = 8e-10
Identities = 40/132 (30%), Positives = 71/132 (53%), Gaps = 1/132 (0%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L +++EL L N++ ++ + F L LDL N + ++ N F L L+ LY+D N
Sbjct: 231 LGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRN 290
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
+ ++ F GL+ L +L++ +N + +L TF + LR+L L++N + SL F
Sbjct: 291 LIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKD 350
Query: 494 VS-LSKLSLHNN 504
+ L +L L +N
Sbjct: 351 LHFLEELQLGHN 362
Score = 63.2 bits (152), Expect = 8e-10
Identities = 49/178 (27%), Positives = 82/178 (46%), Gaps = 26/178 (14%)
Query: 58 SQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNK 117
++ L L N+L + N F L+++ N + + PGAFLGL+ ++ L +++N+
Sbjct: 256 AELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNR 315
Query: 118 ------------------------IKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDL 153
I S R +TF L LE LQ N +R + +F+ L
Sbjct: 316 VAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGL 375
Query: 154 NKLEVLILNDNLISTLPANVF-QYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLE 210
+LEVL L+ N + + A F + ++L GN L+ LP E+V + + + LE
Sbjct: 376 GQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLP-EQVFRGLGKLHSLHLE 432
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L + L L + + IR F L L L +N + +E + L +L L + SN
Sbjct: 423 LGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSN 482
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
L L F GL LEYL + N + + + + L +++N L +LP + A
Sbjct: 483 QLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAP 542
Query: 494 VS-LSKLSLHNNYF-MYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWA 544
+ L LSL NN + P L++L L GNPW+C C + + +A
Sbjct: 543 LGRLRYLSLRNNSLRTFTPQPPGLERLW------LEGNPWDCGCPLKALRDFA 589
Score = 60.1 bits (144), Expect = 7e-09
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L L N + +L F L +++N L E+ GAFLGL V ++++ N +++
Sbjct: 357 LQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLP 416
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDN-LISTLPANVFQYVPITH 181
+Q F GL L L + + L I P F L+ L L L DN L+ +++ +
Sbjct: 417 EQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLE 476
Query: 182 LDLRGNRLKTLPY 194
LDL N+L LP+
Sbjct: 477 LDLTSNQLTHLPH 489
Score = 59.3 bits (142), Expect = 1e-08
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 29/215 (13%)
Query: 341 CPGGCSCDHIPGSG-LKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYK 399
CP C C + + L + C++RN++ L D P Q L+L N + S+ + F +
Sbjct: 79 CPAACVCSYDDDADELSVFCSSRNLTRLPDGVP--GGTQALWLDGNNLSSVPPAAFQNLS 136
Query: 400 NLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFA--------------- 444
+L L+L + ++E L +L L+++ N L +L+ FA
Sbjct: 137 SLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRL 196
Query: 445 ---------GLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS 495
GL +L LN+ +N++ ++ F + LR L+L N L L +F+G++
Sbjct: 197 SRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLA 256
Query: 496 -LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
L +L L N + A V QL + ++ L N
Sbjct: 257 ELRELDLSRNALRAIK-ANVFVQLPRLQKLYLDRN 290
Score = 57.4 bits (137), Expect = 4e-08
Identities = 43/138 (31%), Positives = 72/138 (52%), Gaps = 6/138 (4%)
Query: 380 LFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLS 439
L L +N++ + F +L L+LG N++A + + F+ L LR L + N L L
Sbjct: 189 LGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQ 248
Query: 440 REKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSK 498
F+GL L L++ NA++ I F +P+L+ L L+ NL+ ++ F G+ +L
Sbjct: 249 PALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRW 308
Query: 499 LSLHNNYFMYLPVAGVLD 516
L L +N VAG+L+
Sbjct: 309 LDLSHN-----RVAGLLE 321
Score = 52.8 bits (125), Expect = 1e-06
Identities = 38/117 (32%), Positives = 51/117 (43%)
Query: 62 HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 121
HL L N L L FA+ SL + NN L + G F GL + L++ N +
Sbjct: 164 HLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVL 223
Query: 122 RKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP 178
F GL L L N L + P F L +L L L+ N + + ANVF +P
Sbjct: 224 PDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 280
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/150 (29%), Positives = 70/150 (46%), Gaps = 2/150 (1%)
Query: 357 MNCNNRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVE 415
+ +N +S L D L L ++ +L L N + + + F +L L L N +A ++
Sbjct: 189 LGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQ 248
Query: 416 NNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRI 475
F L +LR L + N L + F L L+ L ++ N I + PG F + LR
Sbjct: 249 PALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRW 308
Query: 476 LILNNNLLRSLPVDVFAG-VSLSKLSLHNN 504
L L++N + L D F G + L L L +N
Sbjct: 309 LDLSHNRVAGLLEDTFPGLLGLRVLRLSHN 338
Score = 49.7 bits (117), Expect = 9e-06
Identities = 34/114 (29%), Positives = 54/114 (47%)
Query: 61 YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS 120
+ L L NSL L F + L + N L + P F GL ++ L ++ N +++
Sbjct: 211 WDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA 270
Query: 121 FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
+ F+ L L+ L D NL+ + PGAF L L L L+ N ++ L + F
Sbjct: 271 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTF 324
>gi|4826772 insulin-like growth factor binding protein, acid labile
subunit isoform 2 precursor [Homo sapiens]
Length = 605
Score = 87.8 bits (216), Expect = 3e-17
Identities = 69/238 (28%), Positives = 100/238 (42%), Gaps = 42/238 (17%)
Query: 65 LHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQ 124
L GN L L F SLH+E + L I P F GL ++RL + +N + +Q
Sbjct: 369 LSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQ 428
Query: 125 TFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITH--- 181
+ GL +L L N L + FQ L KLE L+L+ N ++ LPA+ P+
Sbjct: 429 SLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALG--PLQRAFW 486
Query: 182 LDLRGNRLKTLP-------------------YEEVLEQIPGIAEILLEDNPWDCTCDLLS 222
LD+ NRL+ LP Q PG+ + LE NPWDC C L +
Sbjct: 487 LDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGLERLWLEGNPWDCGCPLKA 546
Query: 223 LKEW-LEN-----------------IPKNALIGRVVCEAPTRLQGKDLNETTEQDLCP 262
L+++ L+N P + C +P + G DL + +E P
Sbjct: 547 LRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAP 604
Score = 70.9 bits (172), Expect = 4e-12
Identities = 57/168 (33%), Positives = 82/168 (48%), Gaps = 6/168 (3%)
Query: 367 LADLKPKL----SNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNL 422
LA L+P L + ++EL L N + +I+ + FV L L L N IA V F L
Sbjct: 206 LAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGL 265
Query: 423 LDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNL 482
LRWL + N + L + F GL L L + +NAI + P TF + L L L +N
Sbjct: 266 KALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNR 325
Query: 483 LRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
+R L F G+ L L+L +N + AG LT++ ++L GN
Sbjct: 326 IRQLAERSFEGLGQLEVLTLDHNQLQEVK-AGAFLGLTNVAVMNLSGN 372
Score = 68.9 bits (167), Expect = 1e-11
Identities = 59/198 (29%), Positives = 90/198 (45%), Gaps = 8/198 (4%)
Query: 1 MLLWILLLETSLCFA----AGNVTGDVCKEK-ICSCNEIEGDLHVDCEKKGFTSLQRFTA 55
+L W+ L SL A G G C +CS ++ +L V C + T L
Sbjct: 14 LLSWVALGPRSLEGADPGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVP 73
Query: 56 PTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINN 115
+Q L+L GN+L+ + P F N + L+++ L + P A LGL+ + LH+
Sbjct: 74 GGTQA--LWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLER 131
Query: 116 NKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQ 175
N+++S TF L L N L ++ G F+ L L L L N ++ LP F+
Sbjct: 132 NQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFR 191
Query: 176 YV-PITHLDLRGNRLKTL 192
+ + L L GNRL L
Sbjct: 192 GLGSLRELVLAGNRLAYL 209
Score = 67.0 bits (162), Expect = 6e-11
Identities = 43/144 (29%), Positives = 77/144 (53%), Gaps = 1/144 (0%)
Query: 368 ADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRW 427
A++ +L +Q+L+L N I ++ F+ K L LDL +N +A + +TF LL LR
Sbjct: 235 ANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRV 294
Query: 428 LYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLP 487
L + N + +L F L LE L + +N I+ + +F + +L +L L++N L+ +
Sbjct: 295 LRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVK 354
Query: 488 VDVFAGV-SLSKLSLHNNYFMYLP 510
F G+ +++ ++L N LP
Sbjct: 355 AGAFLGLTNVAVMNLSGNCLRNLP 378
Score = 65.9 bits (159), Expect = 1e-10
Identities = 44/130 (33%), Positives = 69/130 (53%), Gaps = 3/130 (2%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L ++ L L N++ + + F L +L L +N IA++ TFK+L L L + N
Sbjct: 265 LKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHN 324
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
+ L+ F GL LE L +++N +Q + G F + + ++ L+ N LR+LP VF G
Sbjct: 325 RIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRG 384
Query: 494 VSLSKL-SLH 502
L KL SLH
Sbjct: 385 --LGKLHSLH 392
Score = 65.1 bits (157), Expect = 2e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 360 NNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTF 419
+NR L D P L ++ L L N I S+R F D L L LG+N I + +F
Sbjct: 275 HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF 334
Query: 420 KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILN 479
+ L L L +D N L + F GL N+ +N+ N ++ + F + KL L L
Sbjct: 335 EGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLE 394
Query: 480 NNLLRSLPVDVFAGVS-LSKLSLHNNYFMYLPVAGVLDQ----LTSIIQIDLHGN 529
+ L + F G+S L +L L +N + G+ +Q L ++++DL N
Sbjct: 395 GSCLGRIRPHTFTGLSGLRRLFLKDN-----GLVGIEEQSLWGLAELLELDLTSN 444
Score = 63.2 bits (152), Expect = 8e-10
Identities = 40/132 (30%), Positives = 71/132 (53%), Gaps = 1/132 (0%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L +++EL L N++ ++ + F L LDL N + ++ N F L L+ LY+D N
Sbjct: 193 LGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRN 252
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
+ ++ F GL+ L +L++ +N + +L TF + LR+L L++N + SL F
Sbjct: 253 LIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKD 312
Query: 494 VS-LSKLSLHNN 504
+ L +L L +N
Sbjct: 313 LHFLEELQLGHN 324
Score = 63.2 bits (152), Expect = 8e-10
Identities = 49/178 (27%), Positives = 82/178 (46%), Gaps = 26/178 (14%)
Query: 58 SQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNK 117
++ L L N+L + N F L+++ N + + PGAFLGL+ ++ L +++N+
Sbjct: 218 AELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNR 277
Query: 118 ------------------------IKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDL 153
I S R +TF L LE LQ N +R + +F+ L
Sbjct: 278 VAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGL 337
Query: 154 NKLEVLILNDNLISTLPANVF-QYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLE 210
+LEVL L+ N + + A F + ++L GN L+ LP E+V + + + LE
Sbjct: 338 GQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLP-EQVFRGLGKLHSLHLE 394
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Query: 374 LSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSN 433
L + L L + + IR F L L L +N + +E + L +L L + SN
Sbjct: 385 LGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSN 444
Query: 434 YLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAG 493
L L F GL LEYL + N + + + + L +++N L +LP + A
Sbjct: 445 QLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAP 504
Query: 494 VS-LSKLSLHNNYF-MYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWA 544
+ L LSL NN + P L++L L GNPW+C C + + +A
Sbjct: 505 LGRLRYLSLRNNSLRTFTPQPPGLERLW------LEGNPWDCGCPLKALRDFA 551
Score = 60.1 bits (144), Expect = 7e-09
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Query: 63 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 122
L L N + +L F L +++N L E+ GAFLGL V ++++ N +++
Sbjct: 319 LQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLP 378
Query: 123 KQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDN-LISTLPANVFQYVPITH 181
+Q F GL L L + + L I P F L+ L L L DN L+ +++ +
Sbjct: 379 EQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLE 438
Query: 182 LDLRGNRLKTLPY 194
LDL N+L LP+
Sbjct: 439 LDLTSNQLTHLPH 451
Score = 59.3 bits (142), Expect = 1e-08
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 29/215 (13%)
Query: 341 CPGGCSCDHIPGSG-LKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYK 399
CP C C + + L + C++RN++ L D P Q L+L N + S+ + F +
Sbjct: 41 CPAACVCSYDDDADELSVFCSSRNLTRLPDGVP--GGTQALWLDGNNLSSVPPAAFQNLS 98
Query: 400 NLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFA--------------- 444
+L L+L + ++E L +L L+++ N L +L+ FA
Sbjct: 99 SLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRL 158
Query: 445 ---------GLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVS 495
GL +L LN+ +N++ ++ F + LR L+L N L L +F+G++
Sbjct: 159 SRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLA 218
Query: 496 -LSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGN 529
L +L L N + A V QL + ++ L N
Sbjct: 219 ELRELDLSRNALRAIK-ANVFVQLPRLQKLYLDRN 252
Score = 57.4 bits (137), Expect = 4e-08
Identities = 43/138 (31%), Positives = 72/138 (52%), Gaps = 6/138 (4%)
Query: 380 LFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLS 439
L L +N++ + F +L L+LG N++A + + F+ L LR L + N L L
Sbjct: 151 LGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQ 210
Query: 440 REKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSK 498
F+GL L L++ NA++ I F +P+L+ L L+ NL+ ++ F G+ +L
Sbjct: 211 PALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRW 270
Query: 499 LSLHNNYFMYLPVAGVLD 516
L L +N VAG+L+
Sbjct: 271 LDLSHN-----RVAGLLE 283
Score = 52.8 bits (125), Expect = 1e-06
Identities = 38/117 (32%), Positives = 51/117 (43%)
Query: 62 HLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSF 121
HL L N L L FA+ SL + NN L + G F GL + L++ N +
Sbjct: 126 HLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVL 185
Query: 122 RKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVP 178
F GL L L N L + P F L +L L L+ N + + ANVF +P
Sbjct: 186 PDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/150 (29%), Positives = 70/150 (46%), Gaps = 2/150 (1%)
Query: 357 MNCNNRNVSSLAD-LKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVE 415
+ +N +S L D L L ++ +L L N + + + F +L L L N +A ++
Sbjct: 151 LGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQ 210
Query: 416 NNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRI 475
F L +LR L + N L + F L L+ L ++ N I + PG F + LR
Sbjct: 211 PALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRW 270
Query: 476 LILNNNLLRSLPVDVFAG-VSLSKLSLHNN 504
L L++N + L D F G + L L L +N
Sbjct: 271 LDLSHNRVAGLLEDTFPGLLGLRVLRLSHN 300
Score = 49.7 bits (117), Expect = 9e-06
Identities = 34/114 (29%), Positives = 54/114 (47%)
Query: 61 YHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKS 120
+ L L NSL L F + L + N L + P F GL ++ L ++ N +++
Sbjct: 173 WDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRA 232
Query: 121 FRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF 174
+ F+ L L+ L D NL+ + PGAF L L L L+ N ++ L + F
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTF 286
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,959,204
Number of Sequences: 37866
Number of extensions: 1369724
Number of successful extensions: 7600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 226
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 4186
Number of HSP's gapped (non-prelim): 1642
length of query: 696
length of database: 18,247,518
effective HSP length: 109
effective length of query: 587
effective length of database: 14,120,124
effective search space: 8288512788
effective search space used: 8288512788
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.