Guide to the Human Genome
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Search of human proteins with 39777586

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
         (1386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...  2756   0.0  
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1...   614   e-175
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2...   598   e-170
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...   576   e-164
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...   460   e-129
gi|166851804 tudor domain containing 9 [Homo sapiens]                 313   1e-84
gi|38505213 YTH domain containing 2 [Homo sapiens]                    281   4e-75
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ...   256   1e-67
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ...   256   1e-67
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi...   240   6e-63
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi...   230   8e-60
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]   196   2e-49
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]    196   2e-49
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...   186   1e-46
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi...   182   3e-45
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi...   180   7e-45
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi...   165   3e-40
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi...   152   2e-36
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po...   136   2e-31
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom...   124   6e-28
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo...    88   7e-17
gi|109452587 family with sequence similarity 98, member B isofor...    53   2e-06
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    52   4e-06
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    52   4e-06
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     51   7e-06
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    51   7e-06
gi|195972866 keratin 10 [Homo sapiens]                                 50   2e-05
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi...    50   2e-05
gi|12056465 fibrillarin [Homo sapiens]                                 48   6e-05
gi|119395750 keratin 1 [Homo sapiens]                                  47   1e-04

>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
            sapiens]
          Length = 1386

 Score = 2756 bits (7144), Expect = 0.0
 Identities = 1386/1386 (100%), Positives = 1386/1386 (100%)

Query: 1    MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDD 60
            MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDD
Sbjct: 1    MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDD 60

Query: 61   GDDFCIFSESRRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQE 120
            GDDFCIFSESRRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQE
Sbjct: 61   GDDFCIFSESRRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQE 120

Query: 121  QDADAGSERGLSGEEEDDEPDCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFT 180
            QDADAGSERGLSGEEEDDEPDCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFT
Sbjct: 121  QDADAGSERGLSGEEEDDEPDCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFT 180

Query: 181  VSPFAVQKLSRYGFNTERCQAVLRMCDGDVGASLEHLLTQCFSETFGERMKISEAVNQIS 240
            VSPFAVQKLSRYGFNTERCQAVLRMCDGDVGASLEHLLTQCFSETFGERMKISEAVNQIS
Sbjct: 181  VSPFAVQKLSRYGFNTERCQAVLRMCDGDVGASLEHLLTQCFSETFGERMKISEAVNQIS 240

Query: 241  LDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQEN 300
            LDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQEN
Sbjct: 241  LDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQEN 300

Query: 301  SLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDASFLYELEIRFS 360
            SLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDASFLYELEIRFS
Sbjct: 301  SLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDASFLYELEIRFS 360

Query: 361  KDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESE 420
            KDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESE
Sbjct: 361  KDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESE 420

Query: 421  IVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEES 480
            IVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEES
Sbjct: 421  IVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEES 480

Query: 481  DEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQE 540
            DEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQE
Sbjct: 481  DEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQE 540

Query: 541  RQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQ 600
            RQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQ
Sbjct: 541  RQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQ 600

Query: 601  PRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQ 660
            PRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQ
Sbjct: 601  PRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQ 660

Query: 661  GVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITI 720
            GVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITI
Sbjct: 661  GVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITI 720

Query: 721  PGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVEEDLRLS 780
            PGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVEEDLRLS
Sbjct: 721  PGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVEEDLRLS 780

Query: 781  LHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVD 840
            LHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVD
Sbjct: 781  LHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVD 840

Query: 841  GKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFV 900
            GKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFV
Sbjct: 841  GKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFV 900

Query: 901  KPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQ 960
            KPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQ
Sbjct: 901  KPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQ 960

Query: 961  RKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSV 1020
            RKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSV
Sbjct: 961  RKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSV 1020

Query: 1021 FSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRC 1080
            FSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRC
Sbjct: 1021 FSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRC 1080

Query: 1081 LDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVR 1140
            LDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVR
Sbjct: 1081 LDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVR 1140

Query: 1141 ASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATG 1200
            ASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATG
Sbjct: 1141 ASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATG 1200

Query: 1201 EEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDG 1260
            EEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDG
Sbjct: 1201 EEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDG 1260

Query: 1261 YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRG 1320
            YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRG
Sbjct: 1261 YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRG 1320

Query: 1321 EFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIV 1380
            EFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIV
Sbjct: 1321 EFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIV 1380

Query: 1381 KLVTTQ 1386
            KLVTTQ
Sbjct: 1381 KLVTTQ 1386


>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
            [Homo sapiens]
          Length = 1008

 Score =  614 bits (1583), Expect = e-175
 Identities = 372/873 (42%), Positives = 528/873 (60%), Gaps = 71/873 (8%)

Query: 520  KICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQ 579
            K+ +  + K+   ++  +   R+ LP++  ++ ++NL+  HQV VISG TGCGKTTQ+ Q
Sbjct: 183  KLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQ 242

Query: 580  FILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGL--TVGYQIRLES-VKS 636
            FILD+ +         I+CTQPRRISAISVAERVA ERAE  G   + GYQIRL+S +  
Sbjct: 243  FILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPR 302

Query: 637  SATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQV 696
                +LYCTTG++L+ L+ D  L  VSHI++DE+HER  +SD L+ V+KD+++ R  L+V
Sbjct: 303  KQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKV 362

Query: 697  ILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQI 756
            ILMSATLNAE FS+YF +CP+I IPG TFPV ++ LED I   RYV +          Q 
Sbjct: 363  ILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQ----KEHRSQF 418

Query: 757  SKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIK 816
             +  ++   NR   EE E               K+  PD     ++L  RY   S S + 
Sbjct: 419  KRGFMQGHVNRQEKEEKEA------------IYKERWPDY---VRELRRRY---SASTVD 460

Query: 817  TMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNR 876
             + +M+ +KV+L LI AL+ +IV  +     GAILVFLPG   I  L++ L S  +F   
Sbjct: 461  VIEMMEDDKVDLNLIVALIRYIVLEEED---GAILVFLPGWDNISTLHDLLMSQVMF--- 514

Query: 877  RSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936
            +S++ +I PLHS + +  Q  VF + P GV KI+I+TNIAETSITIDDVVYVID GK+KE
Sbjct: 515  KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKE 574

Query: 937  KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996
              +D    + ++   +VS+ANA QRKGRAGRV  G C+HL+     +  L   QLPEI R
Sbjct: 575  THFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRAS-LLDDYQLPEILR 633

Query: 997  VPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLG 1056
             PLE+LCL+IKIL +     +    SRL++PP  +++  S   L +L AL   E LTPLG
Sbjct: 634  TPLEELCLQIKILRL---GGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLG 690

Query: 1057 YHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFA- 1115
             HLA LPV+  IGK++LFG++F CLDP LTIAASL+FK PFV P  K++ A+ ++ E A 
Sbjct: 691  VHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAK 750

Query: 1116 FANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGF 1175
               SD+L ++ A++GW+ + + G R   +YC + FLS   LQ + ++K QF E L   GF
Sbjct: 751  DTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF 810

Query: 1176 AREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKF 1235
                                 +    E+N N++N K+I A++CA LYP V +++   GK 
Sbjct: 811  VSS-----------------RNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKK 853

Query: 1236 QKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIR 1295
            +K              +K  TK DG V +HP SVN +   F   +L+YH K++TS +++ 
Sbjct: 854  RKM-------------VKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 900

Query: 1296 DCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLL 1355
            DC+ VS Y L LF GG +++Q    +  +++D+ WI F + + ++A LVKELR ELD LL
Sbjct: 901  DCTEVSPYCL-LFFGGDISIQKDNDQETIAVDE-WIVFQSPA-RIAHLVKELRKELDILL 957

Query: 1356 QDKIKNP-SIDL-CTCPRGSRIISTIVKLVTTQ 1386
            Q+KI++P  +D   T  R   ++S I+ L+ TQ
Sbjct: 958  QEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ 990



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 35/130 (26%), Positives = 50/130 (38%), Gaps = 21/130 (16%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDFCIFSESR 71
           G+ GG  SS GG GG          G GGGGGGGGGG                      R
Sbjct: 10  GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG-----------------GRGR 52

Query: 72  RPSRPSNSNISKGESRPKWKPKAKVPLQ---TLHMTSENQEKVKALLRDLQEQDADAGSE 128
            P       I    ++ + +   +   Q    +HM    +E++  LL  +Q ++ D  SE
Sbjct: 53  HPGHLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKN-DKESE 111

Query: 129 RGLSGEEEDD 138
             +S    +D
Sbjct: 112 AQISWFAPED 121


>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
            [Homo sapiens]
          Length = 994

 Score =  598 bits (1541), Expect = e-170
 Identities = 367/873 (42%), Positives = 517/873 (59%), Gaps = 85/873 (9%)

Query: 520  KICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQ 579
            K+ +  + K+   ++  +   R+ LP++  ++ ++NL+  HQV VISG TGCGKTTQ+ Q
Sbjct: 183  KLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQ 242

Query: 580  FILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGL--TVGYQIRLES-VKS 636
            FILD+ +         I+CTQPRRISAISVAERVA ERAE  G   + GYQIRL+S +  
Sbjct: 243  FILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPR 302

Query: 637  SATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQV 696
                +LYCTTG++L+ L+ D  L  VSHI++DE+HER  +SD L+ V+KD+++ R  L+V
Sbjct: 303  KQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKV 362

Query: 697  ILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQI 756
            ILMSATLNAE FS+YF +CP+I IPG TFPV ++ LED I   RYV +          Q 
Sbjct: 363  ILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQ----KEHRSQF 418

Query: 757  SKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIK 816
             +  ++   NR   EE E               K+  PD     ++L  RY   S S + 
Sbjct: 419  KRGFMQGHVNRQEKEEKEA------------IYKERWPDY---VRELRRRY---SASTVD 460

Query: 817  TMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNR 876
             + +M+ +KV+L LI AL+ +IV  +     GAILVFLPG   I  L++ L S  +F   
Sbjct: 461  VIEMMEDDKVDLNLIVALIRYIVLEEED---GAILVFLPGWDNISTLHDLLMSQVMF--- 514

Query: 877  RSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936
                           S  Q  VF + P GV KI+I+TNIAETSITIDDVVYVID GK+KE
Sbjct: 515  --------------KSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKE 560

Query: 937  KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996
              +D    + ++   +VS+ANA QRKGRAGRV  G C+HL+     +  L   QLPEI R
Sbjct: 561  THFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRAS-LLDDYQLPEILR 619

Query: 997  VPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLG 1056
             PLE+LCL+IKIL +     +    SRL++PP  +++  S   L +L AL   E LTPLG
Sbjct: 620  TPLEELCLQIKILRL---GGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLG 676

Query: 1057 YHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFA- 1115
             HLA LPV+  IGK++LFG++F CLDP LTIAASL+FK PFV P  K++ A+ ++ E A 
Sbjct: 677  VHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAK 736

Query: 1116 FANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGF 1175
               SD+L ++ A++GW+ + + G R   +YC + FLS   LQ + ++K QF E L   GF
Sbjct: 737  DTRSDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGF 796

Query: 1176 AREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKF 1235
                                 +    E+N N++N K+I A++CA LYP V +++   GK 
Sbjct: 797  VSS-----------------RNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKK 839

Query: 1236 QKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIR 1295
            +K              +K  TK DG V +HP SVN +   F   +L+YH K++TS +++ 
Sbjct: 840  RKM-------------VKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 886

Query: 1296 DCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLL 1355
            DC+ VS Y L LF GG +++Q    +  +++D+ WI F + + ++A LVKELR ELD LL
Sbjct: 887  DCTEVSPYCL-LFFGGDISIQKDNDQETIAVDE-WIVFQSPA-RIAHLVKELRKELDILL 943

Query: 1356 QDKIKNP-SIDL-CTCPRGSRIISTIVKLVTTQ 1386
            Q+KI++P  +D   T  R   ++S I+ L+ TQ
Sbjct: 944  QEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ 976



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 35/130 (26%), Positives = 50/130 (38%), Gaps = 21/130 (16%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDFCIFSESR 71
           G+ GG  SS GG GG          G GGGGGGGGGG                      R
Sbjct: 10  GRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRG-----------------GRGR 52

Query: 72  RPSRPSNSNISKGESRPKWKPKAKVPLQ---TLHMTSENQEKVKALLRDLQEQDADAGSE 128
            P       I    ++ + +   +   Q    +HM    +E++  LL  +Q ++ D  SE
Sbjct: 53  HPGHLKGREIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKN-DKESE 111

Query: 129 RGLSGEEEDD 138
             +S    +D
Sbjct: 112 AQISWFAPED 121


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
          Length = 1369

 Score =  576 bits (1484), Expect = e-164
 Identities = 355/941 (37%), Positives = 549/941 (58%), Gaps = 73/941 (7%)

Query: 459  PNNSFVSNQIPEVEKASESEESDEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAEN 518
            P + F++  + ++++  + ++   ++         ES+ NL        D+ A S+ + N
Sbjct: 487  PRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSD----EDFSALSLESAN 542

Query: 519  GK----ICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKT 574
             +    +   FR  Q++ ++Q +L+ERQ LP ++ R++I+  L++H+VVV++G TG GK+
Sbjct: 543  VEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKS 602

Query: 575  TQIPQFILDDSL-NGPPEKVANIICTQPRRISAISVAERVAKERAERVG-----LTVGYQ 628
            TQ+P F+L+D L N       NI+CTQPRRISA+S+A RV  E     G        GYQ
Sbjct: 603  TQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQ 662

Query: 629  IRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIV 688
            IR+ES    +TRLLYCTTGVLLR+L+ D  L  VSH+IVDEVHER+ +SDFLL++LK+I+
Sbjct: 663  IRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEIL 722

Query: 689  SQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSP 748
             +R  L +ILMSAT+++E FS YF  CP++ I GR++PV+ F LED I  T +VL+  S 
Sbjct: 723  QKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSE 782

Query: 749  YMRSMKQISKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYK 808
            Y +   +               EE E  + ++         ++ +P Q      L   Y+
Sbjct: 783  YCQKFLE---------------EEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQ 827

Query: 809  GVSKSVIKTMSIMDFEKVNLELIEALLEWI-VDGKHSYPPGAILVFLPGLAEIKMLYEQL 867
              S      +  M+  K+NL+LI  LL ++    +     GA+L+FLPGLA I+ LY+ L
Sbjct: 828  KYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLL 887

Query: 868  QSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVY 927
             ++  F    S R  +  LHS LS+++Q A F  PP GV KI+++TNIAET ITI DVV+
Sbjct: 888  SNDRRF---YSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVF 944

Query: 928  VIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLL 987
            VID+G+ KE +Y  S  M SL +TFVS+A+ALQR+GRAGRV  G CF ++T   +    +
Sbjct: 945  VIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERF-EGFM 1003

Query: 988  KQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALT 1047
               +PEI RVPLE+LCL I    + S    +   S+ ++PP    +  +   LR +GA  
Sbjct: 1004 DYSVPEILRVPLEELCLHIMKCNLGSP---EDFLSKALDPPQLQVISNAMNLLRKIGACE 1060

Query: 1048 PDE-RLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEE 1106
             +E +LTPLG HLA+LPV+V+IGK+++FG+IF CLDP  T+AA +  KSPF +P  +K+E
Sbjct: 1061 LNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDE 1120

Query: 1107 ANQKKLEFAFANSDYLALLQAYKGWQLSTKE-GVRASYNYCRQNFLSGRVLQEMASLKRQ 1165
            A+  K   A A+SD+L +  AY GW+ + +E G R+   YCR+NFL+   L  +  +K++
Sbjct: 1121 ADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQE 1180

Query: 1166 FTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNV 1225
              +L+   GF+           RA                + +   L+ A+L A LY NV
Sbjct: 1181 LIKLVKAAGFSSSTTSTSWEGNRA------------SQTLSFQEIALLKAVLVAGLYDNV 1228

Query: 1226 VQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHE 1285
             ++           T +V +  K A +  V    G   +HPSSVN  ++     +LLY E
Sbjct: 1229 GKI---------IYTKSVDVTEKLACI--VETAQGKAQVHPSSVNRDLQ--THGWLLYQE 1275

Query: 1286 KIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVK 1345
            KI+ +RV++R+ ++++ +P++LFGG   ++++Q  E ++S+ DGWI F  A  ++A + K
Sbjct: 1276 KIRYARVYLRETTLITPFPVLLFGG---DIEVQHRERLLSI-DGWIYF-QAPVKIAVIFK 1330

Query: 1346 ELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ 1386
            +LR  +D +L+ K++NP + L       +I+  I +L+ T+
Sbjct: 1331 QLRVLIDSVLRKKLENPKMSL----ENDKILQIITELIKTE 1367


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
          Length = 1270

 Score =  460 bits (1183), Expect = e-129
 Identities = 308/862 (35%), Positives = 454/862 (52%), Gaps = 110/862 (12%)

Query: 529  QASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNG 588
            +     Q+ILQER+ LP  +    IL  + ++ VV+I G TGCGKTTQ+PQFILDD +  
Sbjct: 373  EQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQN 432

Query: 589  PPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSA-TRLLYCTTG 647
                  NI+ TQPRRISA+SVAERVA ER E  G + GY +R ES+       +++CT G
Sbjct: 433  DRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVG 492

Query: 648  VLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAEL 707
            VLLR+LE    ++G+SH+IVDE+HER   +DFLL+VL+D+V   P ++++LMSAT++  +
Sbjct: 493  VLLRKLEA--GIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSM 550

Query: 708  FSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNR 767
            F +YF +CP+I + GRT+PV ++FLED I +T +V               K+K K  ++ 
Sbjct: 551  FCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPP------------KDKKKKDKDD 598

Query: 768  TAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVN 827
               E+  +D   +L   D+       P+ +L   QL                  + ++  
Sbjct: 599  DGGED--DDANCNLICGDEYG-----PETRLSMSQL------------------NEKETP 633

Query: 828  LELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLH 887
             ELIEALL++I   +    PGA+LVFLPG   I  + + L+ N  F    S+R  I PLH
Sbjct: 634  FELIEALLKYI---ETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFG---SHRYQILPLH 687

Query: 888  SSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMES 947
            S +  EEQ+ VF   P GVTK+I+STNIAETSITI+DVVYVIDS K K K + A   M +
Sbjct: 688  SQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTN 747

Query: 948  LEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIK 1007
                + S+ N  QRKGRAGRV  G CFHL +   +  +L     PE+ R PL ++ L IK
Sbjct: 748  YATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARF-ERLETHMTPEMFRTPLHEIALSIK 806

Query: 1008 ILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVR 1067
            +L +     +    ++ IEPP  D++  ++  LR+L AL  ++ LTPLG  LA LP++ R
Sbjct: 807  LLRL---GGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDELTPLGRILAKLPIEPR 863

Query: 1068 IGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFAN------SDY 1121
             GK+M+ G IF   D   TIAA+  F  PF++          K+L +   N      SD+
Sbjct: 864  FGKMMIMGCIFYVGDAICTIAAATCFPEPFIN--------EGKRLGYIHRNFAGNRFSDH 915

Query: 1122 LALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLR 1181
            +ALL  ++ W  +   G  A   +C    L+   L+     K Q  E+L + GF  + L 
Sbjct: 916  VALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLL 975

Query: 1182 AREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTG 1241
             +           V   TG + N +     ++ ++L   +YPNV   K            
Sbjct: 976  TQ-----------VFTNTGPDNNLD-----VVISLLAFGVYPNVCYHKE----------- 1008

Query: 1242 AVRMQPKSAELKFVTKNDGYVHIHPSSVN----YQVRHFDSPYLLYHEKIKTSRVFIRDC 1297
                     + K +T       IH SSVN     Q   + SP+ ++ EKI+T  +  +  
Sbjct: 1009 ---------KRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGM 1059

Query: 1298 SMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQD 1357
            ++V+   L+LF   +V    Q     + L D WI+ +  SH+ A  +  LR  ++ L+ +
Sbjct: 1060 TLVTPLQLLLFASKKVQSDGQ-----IVLVDDWIK-LQISHEAAACITGLRAAMEALVVE 1113

Query: 1358 KIKNPSIDLCTCPRGSRIISTI 1379
              K P+I     P   R+++ I
Sbjct: 1114 VTKQPAIISQLDPVNERMLNMI 1135



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 23/53 (43%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 2    SSSVRRKGKPGKGGG-KGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKA 53
            ++S R     G GGG +G SRGG  G S       SGG  G GG   GG R A
Sbjct: 1203 ANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGA 1255



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 8/55 (14%)

Query: 9    GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGG-------GGGGGGGGNRKASSR 56
            G   + GG   S GG GG  ++S  +GSGG GG       G G G GG  +  SR
Sbjct: 1170 GSGYRRGGSSYSGGGYGG-GYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSR 1223



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 23/53 (43%), Positives = 27/53 (50%), Gaps = 4/53 (7%)

Query: 3    SSVRRKGKPGKGGGKG---SSRG-GRGGRSHASKSHGSGGGGGGGGGGGGGNR 51
            S  RR G    GGG G   SS G G GG   ++ S  +G G G GGG  G +R
Sbjct: 1171 SGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSR 1223


>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score =  313 bits (801), Expect = 1e-84
 Identities = 209/652 (32%), Positives = 349/652 (53%), Gaps = 92/652 (14%)

Query: 544  LPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRR 603
            LP    +E +++L+  + VV+I G TG GK+TQ+PQ+ILD  +        +I+ TQPR+
Sbjct: 132  LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQR--SAYCSIVVTQPRK 189

Query: 604  ISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVS 663
            I A S+A  ++KERA  +G  VGYQ+ LE + +  TRL+Y TTGVLL+++    +L   +
Sbjct: 190  IGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFT 249

Query: 664  HIIVDEVHERTEESDFLLLVLKDIVSQRPG-LQVILMSATLNAELFSDYF--------NS 714
            HII+DEVHERTEE DFLLLV++ ++      ++V+LMSAT++ + F+DYF        N 
Sbjct: 250  HIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNP 309

Query: 715  CPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVE 774
              +  + G+   V+++                  Y+  ++ I   KL             
Sbjct: 310  AYIFEVEGKPHSVEEY------------------YLNDLEHIHHSKL------------- 338

Query: 775  EDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEAL 834
                 S HL ++  +   + +              V+ S+I+    +D ++   +     
Sbjct: 339  -----SPHLLEEPVITKDIYE--------------VAVSLIQMFDDLDMKESGNKAWSGA 379

Query: 835  LEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEE 894
             +++++        ++LVFLPGL EI  ++E L   SL + R      ++PLHSS++ EE
Sbjct: 380  -QFVLERS------SVLVFLPGLGEINYMHELL--TSLVHKRLQ----VYPLHSSVALEE 426

Query: 895  QQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVS 954
            Q  VF+ P  G  KII+STNIAE+S+T+ DV YVID    +    D     +SL  ++ S
Sbjct: 427  QNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWAS 486

Query: 955  QANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSA 1014
            + +  QRKGRAGRV+ G C+ L     +++ +    +PE+ R PL    L++K+L+M   
Sbjct: 487  KTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEP 546

Query: 1015 HNLQSVFSRLIEPPHTDSLRASKIRLRDLGALT----------PDERLTPLGYHLASLPV 1064
               +++ +  + PP    +  + + L+++GAL            D  LT LG  LA LPV
Sbjct: 547  ---RALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPV 603

Query: 1065 DVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFA-FANSDYLA 1123
            + ++GKL++ G +F CLD  L IAA+L+ K+ F  P+ +  +  + K+ F+  + SD +A
Sbjct: 604  NQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIA 663

Query: 1124 LLQAYKGWQLSTKEG----VRASYNYCRQNFLSGRVLQEMASLKRQFTELLS 1171
            L++A+K W+   + G     +   N+ R N++  + ++E+A L  +    +S
Sbjct: 664  LVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRIS 715


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score =  281 bits (718), Expect = 4e-75
 Identities = 186/502 (37%), Positives = 284/502 (56%), Gaps = 49/502 (9%)

Query: 822  DFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRR---- 877
            D EKV+L+LI  LL  I    HS   GA+L+FLPG  EI  L +++    LF+++R    
Sbjct: 600  DDEKVDLDLIMHLLYNIC---HSCDAGAVLIFLPGYDEIVGLRDRI----LFDDKRFADN 652

Query: 878  SNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEK 937
            ++R  +  LHS++ + +Q+ V   PPAGV KII+STNIAETSIT++DVV+VIDSGK+KEK
Sbjct: 653  THRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEK 712

Query: 938  RYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRV 997
             +DA   +  L+  ++S+A+A+QRKGRAGR   G+CF LF+   + + +L+ Q PE+ R+
Sbjct: 713  SFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQN-MLEFQTPELLRM 771

Query: 998  PLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGY 1057
            PL++LCL  K+L   +   +     +  EPP    +R +   L+ + A+   E LT LGY
Sbjct: 772  PLQELCLHTKLLAPVNC-PIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGY 830

Query: 1058 HLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEF--- 1114
            HLA LPV+  +GK++L   + +CLDP LTIA +LA++ PFV P     +A+QK+      
Sbjct: 831  HLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLP----TQASQKRAAMLCR 886

Query: 1115 ----AFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELL 1170
                A A SD++ALL+A++ WQ +  +G   +  +C +NFLS   ++ +  ++ Q    L
Sbjct: 887  KRFTAGAFSDHMALLRAFQAWQKARSDGWERA--FCEKNFLSQATMEIIIGMRTQLLGQL 944

Query: 1171 SDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKS 1230
               GF            RA+GG  + D      N+N+EN  ++ A L A +YPN+V V  
Sbjct: 945  RASGFV-----------RARGGGDIRD-----VNTNSENWAVVKAALVAGMYPNLVHVDR 988

Query: 1231 PEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVN-YQVRHFDSPYLLYHEKIKT 1289
                        VR  P S     V     Y  I P++     ++   + +L+Y E  + 
Sbjct: 989  ENLVLTGPKEKKVRFHPAS-----VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRA 1043

Query: 1290 SRVF-IRDCSMVSVYPLVLFGG 1310
             R+  IR CS V+   +++F G
Sbjct: 1044 HRIANIRCCSAVTPVTILVFCG 1065



 Score =  225 bits (573), Expect = 3e-58
 Identities = 133/295 (45%), Positives = 182/295 (61%), Gaps = 22/295 (7%)

Query: 513 SVHAENGKICK----------QFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQV 562
           +V AEN ++ K          Q  +K+   +F S    RQSLP +E++E I+ ++++++V
Sbjct: 155 AVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSF---RQSLPVFEKQEEIVKIIKENKV 211

Query: 563 VVISGMTGCGKTTQIPQFILDDSL-NGPPEKVANIICTQPRRISAISVAERVAKERAERV 621
           V+I G TG GKTTQIPQF+LDD   NG P     I CTQPRR++AI+VAERVA ER ER+
Sbjct: 212 VLIVGETGSGKTTQIPQFLLDDCFKNGIP---CRIFCTQPRRLAAIAVAERVAAERRERI 268

Query: 622 GLTVGYQIRLESVKSSATRLLYCTTGVLLRRL-EGDTALQGVSHIIVDEVHERTEESDFL 680
           G T+GYQIRLES  S  T L +CT GVLLR L  GD+ L  V+H+IVDEVHER   SDFL
Sbjct: 269 GQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFL 328

Query: 681 LLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTR 740
           L  L+D++ + P L++IL SA L+  LF  YF SCPVI I GR F V + FLED +  T 
Sbjct: 329 LTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTG 388

Query: 741 YVLQDGSPYMRSMKQISKEKLKARR----NRTAFEEVEEDLRLSLHLQDQDSVKD 791
           Y  ++   Y +  +Q  K++            +F+   +  R  L++ D+  + D
Sbjct: 389 YTNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLD 443


>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
            sapiens]
          Length = 1155

 Score =  256 bits (653), Expect = 1e-67
 Identities = 169/518 (32%), Positives = 278/518 (53%), Gaps = 33/518 (6%)

Query: 847  PGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGV 906
            PG IL FLPG  EIK + ++LQ          ++ +I P+HS++   +Q+A+F +PP GV
Sbjct: 629  PGGILCFLPGWQEIKGVQQRLQEAL---GMHESKYLILPVHSNIPMMDQKAIFQQPPVGV 685

Query: 907  TKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAG 966
             KI+++TNIAETSITI+D+V+V+DSG  KE+RYD    +  LE  +VS+AN +QR+GRAG
Sbjct: 686  RKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAG 745

Query: 967  RVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIE 1026
            R  SG  +HLF       +++  Q+PEI R PLE L L+ KI             S+ ++
Sbjct: 746  RCQSGFAYHLFPRSRL-EKMVPFQVPEILRTPLENLVLQAKI--HMPEKTAVEFLSKAVD 802

Query: 1027 PPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALT 1086
             P+  ++  + I L+++G L   E LT LG  LA +  D R+ K ++  +IFRCL P L 
Sbjct: 803  SPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLV 862

Query: 1087 IAASLAFKSPFVSPWDKKEEANQKKLEFAF-ANSDYLALLQAYKGWQLSTKEGVRAS-YN 1144
            + + L  + PF S    + E ++ K   +  + SD+LA ++A  GW+   +   R+S  N
Sbjct: 863  VVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN 921

Query: 1145 YCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEAN 1204
            Y  +N L    L+ +  L +QF+E +               E    G          + N
Sbjct: 922  YLEENLLYAPSLRFIHGLIKQFSENI--------------YEAFLVGKPSDCTLASAQCN 967

Query: 1205 SNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHI 1264
              +E  +L+  +L A LYPN++QV+  +GK  +      + +P S  + + TK+ G + +
Sbjct: 968  EYSEEEELVKGVLMAGLYPNLIQVR--QGKVTRQG----KFKPNS--VTYRTKS-GNILL 1018

Query: 1265 HPSSVNYQVRHFDSPYLLYHEKIKTS-RVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFV 1323
            H S++N +     S +L Y   +K++  VF+RD S V    ++L   G V+++       
Sbjct: 1019 HKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRAT 1078

Query: 1324 VSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKN 1361
            +SL D  +  +    +   L+KELR  L ++++  +++
Sbjct: 1079 ISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1116



 Score =  199 bits (506), Expect = 2e-50
 Identities = 103/202 (50%), Positives = 139/202 (68%), Gaps = 1/202 (0%)

Query: 537 ILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANI 596
           + QE   LP    R+TILN + +H VVVISG TGCGKTT+IPQ +L+  +        N+
Sbjct: 388 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 447

Query: 597 ICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSS-ATRLLYCTTGVLLRRLEG 655
           I TQPRRISA+SVA+RV+ E    +   VG+Q+RLES   S    LL+CT G+LLR+L+ 
Sbjct: 448 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 507

Query: 656 DTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSC 715
           + +L+GVSH+IVDEVHER   +DFLL++LK +    P L+++LMSAT + E FS YF  C
Sbjct: 508 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 567

Query: 716 PVITIPGRTFPVDQFFLEDAIA 737
           PVI +PG  +PV + +LED +A
Sbjct: 568 PVIKVPGFMYPVKEHYLEDILA 589


>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
            sapiens]
          Length = 1194

 Score =  256 bits (653), Expect = 1e-67
 Identities = 169/518 (32%), Positives = 278/518 (53%), Gaps = 33/518 (6%)

Query: 847  PGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGV 906
            PG IL FLPG  EIK + ++LQ          ++ +I P+HS++   +Q+A+F +PP GV
Sbjct: 668  PGGILCFLPGWQEIKGVQQRLQEAL---GMHESKYLILPVHSNIPMMDQKAIFQQPPVGV 724

Query: 907  TKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAG 966
             KI+++TNIAETSITI+D+V+V+DSG  KE+RYD    +  LE  +VS+AN +QR+GRAG
Sbjct: 725  RKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAG 784

Query: 967  RVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIE 1026
            R  SG  +HLF       +++  Q+PEI R PLE L L+ KI             S+ ++
Sbjct: 785  RCQSGFAYHLFPRSRL-EKMVPFQVPEILRTPLENLVLQAKI--HMPEKTAVEFLSKAVD 841

Query: 1027 PPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALT 1086
             P+  ++  + I L+++G L   E LT LG  LA +  D R+ K ++  +IFRCL P L 
Sbjct: 842  SPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLV 901

Query: 1087 IAASLAFKSPFVSPWDKKEEANQKKLEFAF-ANSDYLALLQAYKGWQLSTKEGVRAS-YN 1144
            + + L  + PF S    + E ++ K   +  + SD+LA ++A  GW+   +   R+S  N
Sbjct: 902  VVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN 960

Query: 1145 YCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEAN 1204
            Y  +N L    L+ +  L +QF+E +               E    G          + N
Sbjct: 961  YLEENLLYAPSLRFIHGLIKQFSENI--------------YEAFLVGKPSDCTLASAQCN 1006

Query: 1205 SNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHI 1264
              +E  +L+  +L A LYPN++QV+  +GK  +      + +P S  + + TK+ G + +
Sbjct: 1007 EYSEEEELVKGVLMAGLYPNLIQVR--QGKVTRQG----KFKPNS--VTYRTKS-GNILL 1057

Query: 1265 HPSSVNYQVRHFDSPYLLYHEKIKTS-RVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFV 1323
            H S++N +     S +L Y   +K++  VF+RD S V    ++L   G V+++       
Sbjct: 1058 HKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRAT 1117

Query: 1324 VSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKN 1361
            +SL D  +  +    +   L+KELR  L ++++  +++
Sbjct: 1118 ISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRS 1155



 Score =  199 bits (506), Expect = 2e-50
 Identities = 103/202 (50%), Positives = 139/202 (68%), Gaps = 1/202 (0%)

Query: 537 ILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANI 596
           + QE   LP    R+TILN + +H VVVISG TGCGKTT+IPQ +L+  +        N+
Sbjct: 427 VWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNV 486

Query: 597 ICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSS-ATRLLYCTTGVLLRRLEG 655
           I TQPRRISA+SVA+RV+ E    +   VG+Q+RLES   S    LL+CT G+LLR+L+ 
Sbjct: 487 IITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQS 546

Query: 656 DTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSC 715
           + +L+GVSH+IVDEVHER   +DFLL++LK +    P L+++LMSAT + E FS YF  C
Sbjct: 547 NPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGC 606

Query: 716 PVITIPGRTFPVDQFFLEDAIA 737
           PVI +PG  +PV + +LED +A
Sbjct: 607 PVIKVPGFMYPVKEHYLEDILA 628


>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapiens]
          Length = 1143

 Score =  240 bits (613), Expect = 6e-63
 Identities = 141/335 (42%), Positives = 191/335 (57%), Gaps = 13/335 (3%)

Query: 843  HSYPP---GAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVF 899
            H YPP   G +LVFL G+AEI  + E  Q+ +      + R V+ PLHS+LS  +Q  VF
Sbjct: 371  HKYPPEERGDLLVFLSGMAEISAVLEAAQTYA----SHTQRWVVLPLHSALSVADQDKVF 426

Query: 900  VKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANAL 959
               P GV K I+STNIAETS+TID + +V+DSGK+KE  YD    ++ L++ ++SQA+A 
Sbjct: 427  DVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAE 486

Query: 960  QRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQS 1019
            QRKGRAGR   GVCF L+    Y+       +PEI+RV L+ L L++K + +        
Sbjct: 487  QRKGRAGRTGPGVCFRLYAESDYD-AFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFP- 544

Query: 1020 VFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFR 1079
                 IEPP   SL  + + LRD GAL   E LTP+G  LA LPVDV IGK+++ GS+F 
Sbjct: 545  ----FIEPPPPASLETAILYLRDQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFS 600

Query: 1080 CLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGV 1139
             ++P LTIAA+L+ +SPF        E    +        D   L   +  W     E  
Sbjct: 601  LVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS 660

Query: 1140 RASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIG 1174
            R S  +CR+  +    L EMA+L+RQF ELL D G
Sbjct: 661  RNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHG 695



 Score =  188 bits (477), Expect = 4e-47
 Identities = 100/234 (42%), Positives = 151/234 (64%), Gaps = 9/234 (3%)

Query: 525 FRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDD 584
           F  KQA  +   + +ER +LP  +    IL  L++HQVVV++G TGCGK+TQ+PQ++L  
Sbjct: 143 FGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAA 202

Query: 585 SLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYC 644
             +       ++ CTQPRRI+ IS+A+RV  E   + G  VGYQIR ES +S+AT++++ 
Sbjct: 203 GFS-------HVACTQPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFL 255

Query: 645 TTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLN 704
           T G+LLR+++ + +L     +IVDEVHER   +DFLL VL+ ++  RP L+VILMSAT+N
Sbjct: 256 TVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATIN 315

Query: 705 AELFSDYFNSCPVITIPGRTFPVDQFF--LEDAIAVTRYVLQDGSPYMRSMKQI 756
             LFS YF++ PV+ +PGR FP+   +   E     ++    D  P++R ++ I
Sbjct: 316 ISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESI 369


>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
          Length = 1157

 Score =  230 bits (586), Expect = 8e-60
 Identities = 196/688 (28%), Positives = 318/688 (46%), Gaps = 85/688 (12%)

Query: 539  QERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIIC 598
            +ER  LP   E + I+  + +H +V++ G TG GKTTQ+PQF+ +   +     +     
Sbjct: 247  EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIG---V 303

Query: 599  TQPRRISAISVAERVAKER--AERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGD 656
            T+PRR++A+++++RVAKE   ++RV   V YQIR E   +  TR+ + T GVLL+ ++ D
Sbjct: 304  TEPRRVAAVAMSQRVAKEMNLSQRV---VSYQIRYEGNVTEETRIKFMTDGVLLKEIQKD 360

Query: 657  TALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPG----LQVILMSATLNAELFSD-- 710
              L     +I+DE HER+  +D L+ +L  IV+ R      L++++MSATL  E F+   
Sbjct: 361  FLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNP 420

Query: 711  --YFNSCPVITIPGRTFPVDQFF-----LED-------AIAVTRYVLQDGSPYMRSMKQI 756
              +    PVI +  R FPV   F     LED        +     +L  G   +    Q 
Sbjct: 421  RLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQA 480

Query: 757  SKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIK 816
                L  RR R AF       +     +  D  KD+V + +  FK+  AR K     V+ 
Sbjct: 481  EVHAL-CRRLRKAFPPSRARPQ-----EKDDDQKDSVEEMR-KFKKSRARAKKARAEVLP 533

Query: 817  TMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNR 876
             +++  +  +     +   E  VD +             G  +  +  +          +
Sbjct: 534  QINLDHYSVLPAGEGDEDREAEVDEEE------------GALDSDLDLDLGDGGQDGGEQ 581

Query: 877  RSNRCVIH--PLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKM 934
                  +H  PL+S L+ E+Q  VF  PP G    +++TN+AETS+TI  + YV+D GK+
Sbjct: 582  PDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKV 641

Query: 935  KEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEI 994
            K++ YD   G+ S   T+VSQA+A QR GRAGR   G C+ L++S  +     +   PEI
Sbjct: 642  KKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFG-DFEQFPPPEI 700

Query: 995  QRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDER--- 1051
             R P+E L L++K L +    N          PP  ++L A++  L  LGAL P ++   
Sbjct: 701  TRRPVEDLILQMKALNVEKVINFP-----FPTPPSVEALLAAEELLIALGALQPPQKAER 755

Query: 1052 ------------LTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVS 1099
                        +T LG  +A+ PV  R  K++       CL  A+TI AS+  +  F  
Sbjct: 756  VKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF-E 814

Query: 1100 PWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEG--------------VRASYNY 1145
              D+   ++++        +    + + + G   S K G                 +  +
Sbjct: 815  ELDRPAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQF 874

Query: 1146 CRQNFLSGRVLQEMASLKRQFTELLSDI 1173
            C  N L  + + E+  L+ Q T  ++ +
Sbjct: 875  CEANGLRYKAMMEIRRLRGQLTTAVNAV 902


>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
          Length = 1041

 Score =  196 bits (497), Expect = 2e-49
 Identities = 123/346 (35%), Positives = 187/346 (54%), Gaps = 11/346 (3%)

Query: 829  ELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHS 888
            + +EA +  ++    + PPG ILVFL G  EI+   E LQ        +    ++ P+++
Sbjct: 590  DYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYA 649

Query: 889  SLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESL 948
            +L S+ Q  +F   P G  K++++TNIAETS TI+ ++YV+D G  K+K Y+   GMESL
Sbjct: 650  NLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESL 709

Query: 949  EDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKI 1008
              T  S+A+A QR GRAGRVA+G CF L+T+  Y H+L +  +PEIQR  L  + L +K 
Sbjct: 710  TVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKS 769

Query: 1009 LEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRI 1068
            L     H+L  +    ++PP  ++L  +  +L  LGAL     LT  G  +A LPVD  +
Sbjct: 770  L---GIHDL--MHFDFLDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPML 824

Query: 1069 GKLMLFGSIFRCLDPALTIAASLAF-KSPFVSPWDKKEEANQKKLEFAFANSDYLALLQA 1127
             K++L    + C +  LT+AA L+   S F  P DK   A+  ++ F     D+L LL  
Sbjct: 825  SKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNV 884

Query: 1128 YKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDI 1173
            Y  W  S       S  +C +NF+  R ++    ++ Q   LL  +
Sbjct: 885  YTQWAES-----GYSSQWCCENFVQFRSMRRARDVREQLEGLLERV 925



 Score =  172 bits (437), Expect = 2e-42
 Identities = 91/201 (45%), Positives = 127/201 (63%), Gaps = 3/201 (1%)

Query: 531 SRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPP 590
           ++Q +SI   R+SLP +  RE +L  +  HQV++I G TG GKTTQIPQ++ ++      
Sbjct: 386 AQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKG 445

Query: 591 EKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLL 650
            K+A   CTQPRR++A+SVA RVA+E   ++G  VGY IR E   S  T L Y T G+LL
Sbjct: 446 MKIA---CTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLL 502

Query: 651 RRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSD 710
           R    +  L   S ++VDE HERT  +D L  ++KD+   RP L+V++ SAT++   FS 
Sbjct: 503 REFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFST 562

Query: 711 YFNSCPVITIPGRTFPVDQFF 731
           +F+  PV  IPGR FPVD F+
Sbjct: 563 FFDDAPVFRIPGRRFPVDIFY 583


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score =  196 bits (497), Expect = 2e-49
 Identities = 140/495 (28%), Positives = 242/495 (48%), Gaps = 66/495 (13%)

Query: 818  MSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEI----KMLYEQLQSNSLF 873
            + I+  ++   + ++A L  ++    + PPG ILVFL G  EI    ++LYE+++S    
Sbjct: 744  VEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLG-- 801

Query: 874  NNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGK 933
                    +I P++S+L SE Q  +F   P G  K++I+TNIAETS+TID + YV+D G 
Sbjct: 802  --PDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGF 859

Query: 934  MKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPE 993
            +K+K Y++  G++ L  T +SQA A QR GRAGR   G C+ L+T   Y  ++L   +PE
Sbjct: 860  VKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPE 919

Query: 994  IQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLT 1053
            IQR  L    L +K +     ++L S     ++ P  ++L  +  +L  LGAL  +  LT
Sbjct: 920  IQRTNLASTVLSLKAM---GINDLLSF--DFMDAPPMETLITAMEQLYTLGALDDEGLLT 974

Query: 1054 PLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLE 1113
             LG  +A  P++  + K+++      C +  LTI + L+ ++ F  P DK+  A+QKK +
Sbjct: 975  RLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAK 1034

Query: 1114 FAFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDI 1173
            F     D+L LL  Y  W+ +     + S  +C +NF+  R L+    +++Q        
Sbjct: 1035 FHQTEGDHLTLLAVYNSWKNN-----KFSNPWCYENFIQARSLRRAQDIRKQML------ 1083

Query: 1174 GFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEG 1233
                                G++D    +  S  ++   +   +C+  + N  + K P+ 
Sbjct: 1084 --------------------GIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAK-KDPQE 1122

Query: 1234 KFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVF 1293
             ++      V                  V+IHPSS  +   +    +++YHE + T++ +
Sbjct: 1123 GYRTLIDQQV------------------VYIHPSSALF---NRQPEWVVYHELVLTTKEY 1161

Query: 1294 IRDCSMVSVYPLVLF 1308
            +R+ + +    LV F
Sbjct: 1162 MREVTTIDPRWLVEF 1176



 Score =  151 bits (382), Expect = 4e-36
 Identities = 82/199 (41%), Positives = 125/199 (62%), Gaps = 4/199 (2%)

Query: 536 SILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVAN 595
           SIL++R+SLP ++ +E ++  +  +Q++++ G TG GKTTQI Q++ +            
Sbjct: 557 SILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSR----GK 612

Query: 596 IICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEG 655
           I CTQPRR++A+SVA+RV++E    +G  VGY IR E   S  T + Y T G+LLR    
Sbjct: 613 IGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLI 672

Query: 656 DTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSC 715
           D  L   + I++DE HERT  +D L  +LK  V +R  +++I+ SATL+A  FS YF   
Sbjct: 673 DPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEA 732

Query: 716 PVITIPGRTFPVDQFFLED 734
           P+ TIPGRT+PV+  + ++
Sbjct: 733 PIFTIPGRTYPVEILYTKE 751


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
          Length = 1227

 Score =  186 bits (472), Expect = 1e-46
 Identities = 128/468 (27%), Positives = 232/468 (49%), Gaps = 59/468 (12%)

Query: 829  ELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHS 888
            + +EA ++  +    S  PG IL+F+PG  +I++  +Q+  + L     +    + P++S
Sbjct: 722  DYVEAAVKQSLQVHLSGAPGDILIFMPGQEDIEVTSDQIVEH-LEELENAPALAVLPIYS 780

Query: 889  SLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESL 948
             L S+ Q  +F K P GV K I++TNIAETS+T+D +++VIDSG  K K ++   GM++L
Sbjct: 781  QLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDAL 840

Query: 949  EDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKI 1008
            +   +SQANA QR GRAGR   G CF L+T   Y ++LL   +PEIQR  L  + L +K 
Sbjct: 841  QIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKS 900

Query: 1009 LEMFSAHNLQSVFS-RLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVR 1067
            L       +Q +     ++PP  D++  S  +L  LGAL     LT  G  +   P+D  
Sbjct: 901  L------GVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPA 954

Query: 1068 IGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQA 1127
            + K+++      C    L I + L+  + F  P  ++EE++Q + +FA   SD+L  L  
Sbjct: 955  LSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNV 1014

Query: 1128 YKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEK 1187
            Y  W+ +    +     +C  +F+  + ++++  ++ Q  +++              +++
Sbjct: 1015 YLQWKNNNYSTI-----WCNDHFIHAKAMRKVREVRAQLKDIM--------------VQQ 1055

Query: 1188 RAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQP 1247
            R       L + G + +       ++   +CAA +    ++K   G++    TG      
Sbjct: 1056 RMS-----LASCGTDWD-------IVRKCICAAYFHQAAKLKG-IGEYVNIRTGMP---- 1098

Query: 1248 KSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIR 1295
                           H+HP+S  + +  +   Y++YHE + T++ +++
Sbjct: 1099 --------------CHLHPTSSLFGM-GYTPDYIVYHELVMTTKEYMQ 1131



 Score =  162 bits (411), Expect = 2e-39
 Identities = 90/229 (39%), Positives = 143/229 (62%), Gaps = 12/229 (5%)

Query: 506 RYDWQAKSVHAENGKICKQFRMKQASRQF---QSILQERQSLPAWEERETILNLLRKHQV 562
           + D++ +   A++ K     R  +AS +F   +SIL++RQ LP +  ++ +L ++R + +
Sbjct: 496 KVDYRTEQKFADHMK-----RKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSI 550

Query: 563 VVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVG 622
           V++ G TG GKTTQ+ Q++ +D           I CTQPRR++A+SVA+RV++E    +G
Sbjct: 551 VIVVGETGSGKTTQLTQYLHEDGYTD----YGMIGCTQPRRVAAMSVAKRVSEEMGGNLG 606

Query: 623 LTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLL 682
             VGY IR E   S  T + Y T G+LLR    +  L   S II+DE HER+  +D L  
Sbjct: 607 EEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFG 666

Query: 683 VLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFF 731
           +L+++V++R  L++I+ SAT++AE F+ +F + P+  IPGRTFPVD  F
Sbjct: 667 LLREVVARRSDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILF 715


>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
           sapiens]
          Length = 795

 Score =  182 bits (461), Expect = 3e-45
 Identities = 99/201 (49%), Positives = 134/201 (66%), Gaps = 5/201 (2%)

Query: 533 QFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILD--DSLNGPP 590
           ++  IL++R  LP WE ++   ++L +HQ  V+ G TG GKTTQIPQ+ ++   SL GP 
Sbjct: 126 RYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPK 185

Query: 591 EKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLL 650
             VA   CTQPRR++A+SVA+RVA E    +G  VGY IR E   S+ T L Y T G+LL
Sbjct: 186 RGVA---CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLL 242

Query: 651 RRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSD 710
           R    D  L+    II+DE HERT  +D L+ VLK++V QR  L+VI+MSATL+A  F  
Sbjct: 243 REAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQI 302

Query: 711 YFNSCPVITIPGRTFPVDQFF 731
           YF++CP++TIPGRT PV+ F+
Sbjct: 303 YFDNCPLLTIPGRTHPVEIFY 323



 Score =  169 bits (429), Expect = 1e-41
 Identities = 110/336 (32%), Positives = 175/336 (52%), Gaps = 16/336 (4%)

Query: 848  GAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPP---- 903
            G +L+FL G  EI    ++++              I PL+S+L  ++QQ +F  PP    
Sbjct: 350  GDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQ 409

Query: 904  --AGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQR 961
              A   K+++STNIAETS+TID VV+VID G  K+K Y+    +ESL  T +S+A+A QR
Sbjct: 410  NGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQR 469

Query: 962  KGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVF 1021
             GRAGR   G CF L+T   Y  ++     PEI R  L  + L++K L +        V 
Sbjct: 470  AGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDL-----VH 524

Query: 1022 SRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCL 1081
               ++PP  ++L  +   L  L AL  D  LT LG  +A  P+D ++ K+++    + C 
Sbjct: 525  FDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCS 584

Query: 1082 DPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRA 1141
            +  L+I A L+    FV P + K+ A++ K+ FA  + D+L LL  Y  ++ +       
Sbjct: 585  NEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQN-----HE 639

Query: 1142 SYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAR 1177
            S  +C  NF++ R L    ++++Q + ++      R
Sbjct: 640  SVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPR 675


>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
          Length = 703

 Score =  180 bits (457), Expect = 7e-45
 Identities = 135/475 (28%), Positives = 231/475 (48%), Gaps = 61/475 (12%)

Query: 829  ELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQL--QSNSLFNNRRSNRCVIHPL 886
            + I++ +E +V    +   G +L FL G  E++ +   L  Q+ +L          + P+
Sbjct: 256  DYIKSTVETVVKIHQTEGDGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPM 315

Query: 887  HSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGME 946
            ++ L S EQ  VF +    V K+I++TN+AETSITI  +VYVID G +K + Y+    +E
Sbjct: 316  YAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIE 375

Query: 947  SLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRI 1006
             L    VSQA+A QR GR GR  SG C+ L+T   ++ +L +  +PE+QR  L  + L++
Sbjct: 376  CLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQL 434

Query: 1007 KILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLT-PLGYHLASLPVD 1065
            K L + +           + PP   S+  +   L  LG L  D RLT PLG  +A  P++
Sbjct: 435  KALGIDNVLRF-----HFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLN 489

Query: 1066 VRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALL 1125
                K++L    F C    L+IAA +  ++ FV P ++K  A +   +FA    D+L +L
Sbjct: 490  PMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTML 549

Query: 1126 QAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREI 1185
              Y+ +    K+       +C+++FL+ + L   A+++ Q  +LL             ++
Sbjct: 550  NIYEAFIKHNKDS-----KWCQEHFLNYKGLVRAATVREQLKKLLVKF----------QV 594

Query: 1186 EKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRM 1245
             +++  GD                P L+   + +  + N  +           STGA R 
Sbjct: 595  PRKSSEGD----------------PDLVLRCIVSGFFANAARFH---------STGAYR- 628

Query: 1246 QPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMV 1300
                       ++D  +HIHP+SV Y  +     +++Y+E I+TS+ ++RD + +
Sbjct: 629  ---------TIRDDHELHIHPASVLYAEK--PPRWVIYNEVIQTSKYYMRDVTAI 672



 Score =  155 bits (393), Expect = 2e-37
 Identities = 90/212 (42%), Positives = 130/212 (61%), Gaps = 14/212 (6%)

Query: 536 SILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVAN 595
           SI Q+RQ LP ++ R  IL L+  +Q VVI G TGCGK+TQIPQ++ +         V  
Sbjct: 46  SIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVG- 104

Query: 596 IICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSS-ATRLLYCTTGVLLRRLE 654
              TQPRR++A++VA RVA+ER   +G  VGY IR +      ATR+ + T G+L+R + 
Sbjct: 105 --VTQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMM 162

Query: 655 GDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFN- 713
            D  L   S I++DE HERT  +D  + +LK I  +R  L++I+ SATL+A+ F D+FN 
Sbjct: 163 VDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQ 222

Query: 714 ---------SCPVITIPGRTFPVDQFFLEDAI 736
                    +C ++T+ GRTFPVD F+L+  +
Sbjct: 223 NETSDPARDTCVILTVEGRTFPVDIFYLQSPV 254


>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
          Length = 707

 Score =  165 bits (417), Expect = 3e-40
 Identities = 129/454 (28%), Positives = 221/454 (48%), Gaps = 62/454 (13%)

Query: 850  ILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKI 909
            ILVFL G  EI+ + +  +  +          ++ PL++SL   +Q  VF   P G  K+
Sbjct: 291  ILVFLTGQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKV 350

Query: 910  IISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVA 969
            IISTNIAETSITI  + YV+D+G +K K+Y+   G+E L    VS+  A QR GRAGR  
Sbjct: 351  IISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGRED 410

Query: 970  SGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPH 1029
            SG+C+ L+T   +  +  K  +PEIQR  L  + L++  +++ +           +  P 
Sbjct: 411  SGICYRLYTEDEF-EKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFD-----FMSKPS 464

Query: 1030 TDSLRASKIRLRDLGALTPDE---RLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALT 1086
             D ++A+  +L  LGAL   +    LTP+G  +A+ P++ +  K +L    F C +  LT
Sbjct: 465  PDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILT 524

Query: 1087 IAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRASYNYC 1146
            I + L+  S   +P  ++EE    + +F  +  D++ LL  Y+     T + +  + ++C
Sbjct: 525  IVSLLSVDSVLHNPPSRREEVQGVRKKFISSEGDHMTLLNIYR-----TFKNLGGNKDWC 579

Query: 1147 RQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSN 1206
            ++NF++ + +  +A                         E RAQ  D  L  +   A+S 
Sbjct: 580  KENFVNSKNMTLVA-------------------------EVRAQLRDICLKMSMPIASSR 614

Query: 1207 AENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHP 1266
             +  + +   L  +L+ +  +++ P+G +  T T     QP              V IHP
Sbjct: 615  GD-VESVRRCLAHSLFMSTAELQ-PDGTYATTDT----HQP--------------VAIHP 654

Query: 1267 SSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMV 1300
            SSV +   H     ++Y E + T++ ++RD  ++
Sbjct: 655  SSVLF---HCKPACVVYTELLYTNKCYMRDLCVI 685



 Score =  145 bits (367), Expect = 2e-34
 Identities = 83/207 (40%), Positives = 125/207 (60%), Gaps = 9/207 (4%)

Query: 530 ASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGP 589
           AS   +++  +R+SLP ++ R  +L  LR     V+ G TG GKTTQIPQ++ +  ++  
Sbjct: 60  ASPYPEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGIS-- 117

Query: 590 PEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVL 649
             +   I  TQPRR++AIS+A RV+ E+   +G  VGY +R + V S  TR+ + T G+L
Sbjct: 118 --RQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKFLTDGML 175

Query: 650 LRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRP-----GLQVILMSATLN 704
           LR    D+ L+  S +I+DE HERT  +D L  V+K    +R       L+VI+MSAT++
Sbjct: 176 LREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIVMSATMD 235

Query: 705 AELFSDYFNSCPVITIPGRTFPVDQFF 731
            +LFS YFN  PV+ + GR  P+  F+
Sbjct: 236 VDLFSQYFNGAPVLYLEGRQHPIQVFY 262


>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
          Length = 779

 Score =  152 bits (385), Expect = 2e-36
 Identities = 124/483 (25%), Positives = 231/483 (47%), Gaps = 60/483 (12%)

Query: 824  EKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIK----MLYEQLQSNSL---FNNR 876
            ++ N   I+A++E  +D   +   G ILVFL G  EI+    +L++  +S        + 
Sbjct: 249  DRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDT 308

Query: 877  RSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936
              +  +I P + S+++++Q+ +F+ PP G+ K +ISTNI+ TS+TID + YV+D G +K+
Sbjct: 309  TLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQ 368

Query: 937  KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996
              ++   G++ LE   +S++ ALQR GRAGR +SG CF +++   +N  +    +PEI+R
Sbjct: 369  LNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKR 428

Query: 997  VPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLG 1056
              L  + L +K L +        +    ++PP+   +  +  +L    A+     +T LG
Sbjct: 429  TSLTSVVLTLKCLAIHDV-----IRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLG 483

Query: 1057 YHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDK--KEEANQKKLEF 1114
              +   P+   +   ++  +   C D  L IAA L+ ++ F+ P D   ++EA Q+  E 
Sbjct: 484  LSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHREL 543

Query: 1115 AFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIG 1174
            A     +         ++     G  AS  +C+++++  R L     ++ Q  EL+    
Sbjct: 544  AAKAGGFNDFATLAVIFEQCKSSGAPAS--WCQKHWIHWRCLFSAFRVEAQLRELI---- 597

Query: 1175 FAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPK--LISAMLCAALYPNVVQVKSPE 1232
                    R++++++           +      E PK  ++   LCA  + NV   +   
Sbjct: 598  --------RKLKQQS-----------DFPKETFEGPKHEVLRRCLCAGYFKNV--ARRSV 636

Query: 1233 GKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRV 1292
            G+   T  G  R  P              VHIHPSS  ++ +     ++++HE + T++V
Sbjct: 637  GRTFCTVDG--RGSP--------------VHIHPSSALHE-QETKLEWIIFHEVLVTTKV 679

Query: 1293 FIR 1295
            + R
Sbjct: 680  YAR 682



 Score =  136 bits (342), Expect = 2e-31
 Identities = 73/194 (37%), Positives = 118/194 (60%), Gaps = 9/194 (4%)

Query: 543 SLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPR 602
           + P  ++R+ I+  +R +  ++++G TG GKTTQ+P+++ +   +    +   I  TQPR
Sbjct: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS----QHGMIGVTQPR 107

Query: 603 RISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGV 662
           +++AISVA+RVA+E    +G  VGYQ+R +   S  T + Y T G LL+ + GD  L   
Sbjct: 108 KVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKF 167

Query: 663 SHIIVDEVHERTEESDFLLLVLKDIV-----SQRPGLQVILMSATLNAELFSDYFNSCPV 717
           S II+DE HERT  +D L  +LK +      +++  L+V++MSAT+     S +F +CP+
Sbjct: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227

Query: 718 ITIPGRTFPVDQFF 731
             IPGR +PV + F
Sbjct: 228 FDIPGRLYPVREKF 241


>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
           polypeptide 40 [Homo sapiens]
          Length = 452

 Score =  136 bits (342), Expect = 2e-31
 Identities = 73/194 (37%), Positives = 118/194 (60%), Gaps = 9/194 (4%)

Query: 543 SLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPR 602
           + P  ++R+ I+  +R +  ++++G TG GKTTQ+P+++ +   +    +   I  TQPR
Sbjct: 52  TFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFS----QHGMIGVTQPR 107

Query: 603 RISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGV 662
           +++AISVA+RVA+E    +G  VGYQ+R +   S  T + Y T G LL+ + GD  L   
Sbjct: 108 KVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKF 167

Query: 663 SHIIVDEVHERTEESDFLLLVLKDIV-----SQRPGLQVILMSATLNAELFSDYFNSCPV 717
           S II+DE HERT  +D L  +LK +      +++  L+V++MSAT+     S +F +CP+
Sbjct: 168 SVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPI 227

Query: 718 ITIPGRTFPVDQFF 731
             IPGR +PV + F
Sbjct: 228 FDIPGRLYPVREKF 241



 Score =  117 bits (293), Expect = 8e-26
 Identities = 65/193 (33%), Positives = 116/193 (60%), Gaps = 7/193 (3%)

Query: 824  EKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIK----MLYEQLQSNSLFNNRRS- 878
            ++ N   I+A+++  +D   +   G ILVFL G  EI+    +L++  +S     + +  
Sbjct: 249  DRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDT 308

Query: 879  --NRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKE 936
              +  +I P + S+++++Q+ +F+ PP G+ K +ISTNI+ TS+TID + YV+D G +K+
Sbjct: 309  ILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQ 368

Query: 937  KRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQR 996
              ++   G++ LE   +S++ ALQR GRAGR +SG CF +++   +N  +    +PEI+R
Sbjct: 369  LNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKR 428

Query: 997  VPLEQLCLRIKIL 1009
              L  + L +K L
Sbjct: 429  TSLTSVVLTLKCL 441


>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
           sapiens]
          Length = 743

 Score =  124 bits (311), Expect = 6e-28
 Identities = 68/205 (33%), Positives = 120/205 (58%), Gaps = 2/205 (0%)

Query: 531 SRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPP 590
           S ++  +L+ER+ LP W+E+ + +  L ++Q+V++SG   CGK+ Q+PQ+  +  L+   
Sbjct: 49  SSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHY 108

Query: 591 EKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLL 650
           +    +ICTQ  + + + +A RVA E    +G  VGY I  E+  ++ T L YCT  +L 
Sbjct: 109 QH-GGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQ 167

Query: 651 RRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSD 710
           R +  +  L     II+D++HER+  +D LL +LKD++  RP L++I+ S+       + 
Sbjct: 168 REMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNS 227

Query: 711 YFNSCPVITIPGRTFPVDQFFLEDA 735
           Y+ + PVI +  +  PV+  +L +A
Sbjct: 228 YYGNVPVIEVKNK-HPVEVVYLSEA 251



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 88/367 (23%), Positives = 155/367 (42%), Gaps = 22/367 (5%)

Query: 818  MSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRR 877
            + ++   +   +  E++L  I +  HS   G I+VFL    +I+ + E +   S  N   
Sbjct: 243  VEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQGSNLNPDL 302

Query: 878  SNRCVIHPLHSSLSSEEQQAVFVKPPAGVTK--------IIISTNIAETSITIDDVVYVI 929
                V+ PL+      +++    KP     K        ++++T+  E  I  + V +VI
Sbjct: 303  GELVVV-PLYP-----KEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVI 356

Query: 930  DSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQ 989
            D G  + K Y+      SL    +SQ+ A  RK   G  +SG  F L+T    +  +   
Sbjct: 357  DVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPL 416

Query: 990  QLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPD 1049
            +  E+Q   L  + L +K +++    +        +  P  +SL  +   L  L AL  D
Sbjct: 417  KPAEMQEANLTSMVLFMKRIDIAGLGHCD-----FMNRPAPESLMQALEDLDYLAALDND 471

Query: 1050 ERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVS-PWDKKEEAN 1108
              L+  G  ++  P+D ++ K +L    F C+D  LTIAA +   + F   P   +E A 
Sbjct: 472  GNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAAL 531

Query: 1109 QKKLEFAFANSDYLALLQAYKGWQLST--KEGVRASYNYCRQNFLSGRVLQEMASLKRQF 1166
                 F     D+  L+  YK +Q +T           +CR  FL+   L+    ++ + 
Sbjct: 532  TCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAEL 591

Query: 1167 TELLSDI 1173
             E++  I
Sbjct: 592  LEIIKRI 598


>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
           sapiens]
          Length = 717

 Score = 87.8 bits (216), Expect = 7e-17
 Identities = 62/195 (31%), Positives = 103/195 (52%), Gaps = 5/195 (2%)

Query: 531 SRQFQSILQERQSLPAWEERETILNLLRKHQ--VVVISGMTGCGKTTQIPQFILDDSLNG 588
           S ++  +L++RQ+LP W  R T L  L  +   VV++SG  G GK+TQIPQ+  + +L  
Sbjct: 32  SSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALAR 91

Query: 589 PPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGV 648
             +K   +  TQP  ++A S+A RVA E    +G  VGY I  E      T L +C   +
Sbjct: 92  GFQK-GQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRL 150

Query: 649 LLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDI-VSQRPG-LQVILMSATLNAE 706
           LL+ +           +++DE  ER+  SD L  +L+D  + + PG L+V++++      
Sbjct: 151 LLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEP 210

Query: 707 LFSDYFNSCPVITIP 721
               ++ + P++ IP
Sbjct: 211 KLRAFWGNPPIVHIP 225



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 89/348 (25%), Positives = 144/348 (41%), Gaps = 24/348 (6%)

Query: 831  IEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQL--QSNSLFNNRRSNRCVIHPLHS 888
            +EA  + +++      PG +LVFLP   EI +  E L  +  SL       R +  PLH 
Sbjct: 245  VEAACQAVLELCRKELPGDVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVL--PLHP 302

Query: 889  SLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESL 948
                   QAV+    A   K++++  +A+ S ++  + +VIDSG      Y+     E  
Sbjct: 303  DCG-RAVQAVYEDMDA--RKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQ 359

Query: 949  EDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIK- 1007
                +S+  A  R+ RA     G C  L+       +      P +    L  L L +K 
Sbjct: 360  VLRPISKCQAEARRLRARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKR 419

Query: 1008 --ILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVD 1065
              I E    H         ++ P  ++L  +   L  L AL  D  L+ LG  L+  P+ 
Sbjct: 420  RQIAEPGECH--------FLDQPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLA 471

Query: 1066 VRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALL 1125
              + K +L    F C+D  LT+AA L     F  P    EEA  ++      + D+ +L+
Sbjct: 472  PELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEAALRR-ALEHTDGDHSSLI 530

Query: 1126 QAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDI 1173
            Q Y+ +  S      A   +C+   L+   L +   L+ +  EL+  I
Sbjct: 531  QVYEAFIQS-----GADEAWCQARGLNWAALCQAHKLRGELLELMQRI 573


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 28/50 (56%), Positives = 33/50 (66%), Gaps = 5/50 (10%)

Query: 7   RKGKPGKG--GGKGS--SRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRK 52
           R G  G+G  GG+G    RGG GGR +    +G GGGGGGGGGGGGG R+
Sbjct: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDP-YGGGGGGGGGGGGGGGYRR 432



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 26/44 (59%), Positives = 27/44 (61%), Gaps = 3/44 (6%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGG-GGGGGGNR 51
           G  G+GGG G   GGRGG        G GGGGGGG GGGGGG R
Sbjct: 343 GGGGRGGGGGG--GGRGGWGGGGGGWGGGGGGGGGWGGGGGGGR 384



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 25/48 (52%), Positives = 28/48 (58%), Gaps = 4/48 (8%)

Query: 6   RRKGKPGKGG----GKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           R++G  G+GG    G G  RGG GG        G GGG GGGGGGGGG
Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGG 375



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 22/41 (53%), Positives = 23/41 (56%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G  G GGG+G   GG G         G GGGGGGGGG GGG
Sbjct: 339 GGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGG 379



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 24/50 (48%), Positives = 24/50 (48%)

Query: 7   RKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSR 56
           R G  G GGG G   GG GG        G G GGGGGGGGG G      R
Sbjct: 335 RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGR 384



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 21/41 (51%), Positives = 22/41 (53%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G+ G GGG G    G GG        G GG GGGGGGG GG
Sbjct: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 21/48 (43%), Positives = 22/48 (45%)

Query: 14  GGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDG 61
           GGG+G   GG GG        G G GG GGGGGG G        W  G
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGG 379



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 20/40 (50%), Positives = 22/40 (55%)

Query: 8   KGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGG 47
           +G  G GGG+G   GG GG        G  GGGGGGG GG
Sbjct: 347 RGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 20/41 (48%), Positives = 20/41 (48%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G  G GG  G   GGRGG        G GG GG GG GG G
Sbjct: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRG 409



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 20/40 (50%), Positives = 20/40 (50%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNR 51
           G GGG G   GG GGR         GG GG GG GG G R
Sbjct: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 15/35 (42%), Positives = 15/35 (42%)

Query: 27  RSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDG 61
           R       G  GGGGGGGG GGG        W  G
Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG 362


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 22/41 (53%), Positives = 24/41 (58%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G PG  G   +S GG GG      +   GGGGGGGGGGGGG
Sbjct: 198 GAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGG 238



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 8/48 (16%)

Query: 2   SSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           S++    G  G GGG  +S GG GG        G GGGGGGG  G GG
Sbjct: 205 SAAASAGGAGGAGGGGPASAGGGGG--------GGGGGGGGGAAGAGG 244


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 22/41 (53%), Positives = 24/41 (58%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G PG  G   +S GG GG      +   GGGGGGGGGGGGG
Sbjct: 198 GAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGG 238



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 8/48 (16%)

Query: 2   SSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           S++    G  G GGG  +S GG GG        G GGGGGGG  G GG
Sbjct: 205 SAAASAGGAGGAGGGGPASAGGGGG--------GGGGGGGGGAAGAGG 244


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 37/89 (41%), Positives = 40/89 (44%), Gaps = 12/89 (13%)

Query: 8  KGKPGKGGGKGSSRGGRG---GRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDF 64
          KG  G GGG G   GG G   G   +    G GGGGGGGGGGGGG    + RI   G   
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRIL--GGVI 66

Query: 65 CIFSESRR-------PSRPSNSNISKGES 86
             SE+         P R   SNI   ES
Sbjct: 67 SAISEAAAQYNPEPPPPRTHYSNIEANES 95


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 37/89 (41%), Positives = 40/89 (44%), Gaps = 12/89 (13%)

Query: 8  KGKPGKGGGKGSSRGGRG---GRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDF 64
          KG  G GGG G   GG G   G   +    G GGGGGGGGGGGGG    + RI   G   
Sbjct: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRIL--GGVI 66

Query: 65 CIFSESRR-------PSRPSNSNISKGES 86
             SE+         P R   SNI   ES
Sbjct: 67 SAISEAAAQYNPEPPPPRTHYSNIEANES 95


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 34/82 (41%), Positives = 38/82 (46%), Gaps = 9/82 (10%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGG-GGGGGGNRKASSRIWDDGDDFCIF 67
           G  G G G GSS GG GG S      GS GGGGGG GGG  G   +S   +  G      
Sbjct: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGG------ 560

Query: 68  SESRRPSRPSNSNISKGESRPK 89
             S      S+S+ S GES  K
Sbjct: 561 --SSSGGHKSSSSGSVGESSSK 580



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 26/54 (48%), Positives = 27/54 (50%)

Query: 2   SSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
           SSS    G    G G GSS GG GG    S   GS  GGG GGG   G  K+SS
Sbjct: 517 SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSS 570



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 23/45 (51%), Positives = 24/45 (53%)

Query: 6   RRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN 50
           R  G  G G G GSS GG  G  H     GS GGG GGG  GGG+
Sbjct: 464 RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS 508



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 26/54 (48%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 3   SSVRRKGKPGKGG-GKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
           S +  +G  G GG G GS  GG GG S    S G G GGG GG  GGG    SS
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSS 504



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 23/47 (48%), Positives = 23/47 (48%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
           G  G   G GSS GG GG    S   G GGG  GGG  GGG    SS
Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSS 518



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 22/40 (55%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 12  GKGGGKG-SSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN 50
           G GGG G SS GG GG S    S G G GGG   GG GG+
Sbjct: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGS 525



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 2/49 (4%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGG--GGGNRKASS 55
           G    GGG G   GG  G  +   S G G  GGG GGG   GG+  +SS
Sbjct: 479 GGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSS 527



 Score = 39.3 bits (90), Expect = 0.027
 Identities = 19/42 (45%), Positives = 21/42 (50%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN 50
           G  G G G GSS GG  G  +   S   G GG   GG GGG+
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGS 534



 Score = 38.1 bits (87), Expect = 0.059
 Identities = 22/43 (51%), Positives = 22/43 (51%), Gaps = 2/43 (4%)

Query: 9   GKPGKGGGKGSSRGGR--GGRSHASKSHGSGGGGGGGGGGGGG 49
           G    GG  G S GG   GG S    S G GG GGGG GGG G
Sbjct: 90  GSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFG 132



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 15/21 (71%), Positives = 15/21 (71%)

Query: 29 HASKSHGSGGGGGGGGGGGGG 49
          H S S   GGGGGGG GGGGG
Sbjct: 10 HYSSSRSGGGGGGGGCGGGGG 30



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 19/41 (46%), Positives = 20/41 (48%)

Query: 8   KGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGG 48
           +G  G     GS  G  GG S    S G G  GGGG GGGG
Sbjct: 86  RGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGG 126



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 23/51 (45%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 2  SSSVRRKGKPGKGGGKGSSRGGRGGRS--HASKSHGSGGGGGGGGGGGGGN 50
          SSS         GGG G   GG GG S    S S GS GGG   GG  GG+
Sbjct: 6  SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGS 56



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 21/43 (48%), Positives = 22/43 (51%), Gaps = 1/43 (2%)

Query: 9   GKPGKGGGKGSSRGGR-GGRSHASKSHGSGGGGGGGGGGGGGN 50
           G  G   G GS  GG  GG S      G GG GGG GGG GG+
Sbjct: 96  GSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGD 138



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 9   GKPGKGG-GKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G  G GG G GS RG  G  S      GS GGG  GGG  GG
Sbjct: 73  GYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGG 114



 Score = 34.3 bits (77), Expect = 0.85
 Identities = 15/26 (57%), Positives = 19/26 (73%)

Query: 30 ASKSHGSGGGGGGGGGGGGGNRKASS 55
          +S+S G GGGGG GGGGG  + + SS
Sbjct: 13 SSRSGGGGGGGGCGGGGGVSSLRISS 38



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 18/33 (54%), Positives = 21/33 (63%), Gaps = 2/33 (6%)

Query: 27 RSHASKSHGSG--GGGGGGGGGGGGNRKASSRI 57
          R  +SK + S   GGGGGGGG GGG   +S RI
Sbjct: 4  RYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRI 36



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 24/55 (43%), Positives = 25/55 (45%), Gaps = 6/55 (10%)

Query: 3  SSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHG------SGGGGGGGGGGGGGNR 51
          SS+R     G  GG  SS G  GG      S G      SGG GG GG GGG  R
Sbjct: 32 SSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFR 86



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 6/54 (11%)

Query: 8  KGKPGKGGGKGS------SRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
          KG  G G   G       SRG  GG      S G GG GG GGG   G+  +SS
Sbjct: 40 KGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSS 93



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 18/41 (43%), Positives = 19/41 (46%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G  G  GG G   GG    S+ S S G   GG  GGG  GG
Sbjct: 69  GSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG 109



 Score = 32.0 bits (71), Expect = 4.2
 Identities = 18/47 (38%), Positives = 21/47 (44%)

Query: 14  GGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDD 60
           GG  G    G GG        G GGG GG GG   GN K + +  +D
Sbjct: 109 GGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLND 155



 Score = 31.6 bits (70), Expect = 5.5
 Identities = 19/54 (35%), Positives = 22/54 (40%)

Query: 2   SSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
           SSS    G    GGG G   G  GG S +   +G G   GG      G+   SS
Sbjct: 525 SSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESS 578


>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
           sapiens]
          Length = 305

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 34/99 (34%), Positives = 40/99 (40%), Gaps = 20/99 (20%)

Query: 12  GKGGGKGSSRGGRGGRSHAS---------------KSHGSGGGGGGG-----GGGGGGNR 51
           G GGG  SSRGGRGGR                    S+G  GGGGGG     GGGGGG+ 
Sbjct: 183 GGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSS 242

Query: 52  KASSRIWDDGDDFCIFSESRRPSRPSNSNISKGESRPKW 90
              S   +    F  +S+ +    P  S    G     W
Sbjct: 243 YGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSW 281



 Score = 38.9 bits (89), Expect = 0.035
 Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 14/59 (23%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGG--------------GGGGGGGNRKASSR 56
           G GGG  +  GG GG S+    +G+G GG G              GGGGGGG      R
Sbjct: 226 GGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGR 284



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 19/36 (52%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 10  KPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGG 45
           K G GGG G S  G  GRS++    G  GGGGG GG
Sbjct: 269 KSGGGGGGGGSSWG--GRSNSGPYRGGYGGGGGYGG 302



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 21/39 (53%), Positives = 22/39 (56%), Gaps = 6/39 (15%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN 50
           G GGG GSS GGR      S S    GG GGGGG GG +
Sbjct: 272 GGGGGGGSSWGGR------SNSGPYRGGYGGGGGYGGSS 304



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 22/56 (39%), Positives = 24/56 (42%), Gaps = 13/56 (23%)

Query: 14  GGGKGSSRGGR---------GGRSHASKSHG----SGGGGGGGGGGGGGNRKASSR 56
           GGG GSS GG          G  S    S+G     GGGGGGG   GG +     R
Sbjct: 236 GGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYR 291



 Score = 31.2 bits (69), Expect = 7.2
 Identities = 16/36 (44%), Positives = 18/36 (50%)

Query: 14  GGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G  K    GG GG S   +S+     GG GGGGG G
Sbjct: 266 GPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYG 301


>gi|12056465 fibrillarin [Homo sapiens]
          Length = 321

 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 29/58 (50%), Positives = 30/58 (51%), Gaps = 16/58 (27%)

Query: 10 KPG---KGGGKGS-----SRGGRGGRSHASKSHGSG--------GGGGGGGGGGGGNR 51
          KPG   +GGG G       RGGRGGR       G G        GGGGGGGGGGGG R
Sbjct: 2  KPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGR 59



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 23/55 (41%), Positives = 27/55 (49%)

Query: 8  KGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGD 62
          +G  G  GG+G   G  GGR       G G GGGGGGGGGGG  +        G+
Sbjct: 15 RGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGN 69



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 26/51 (50%), Positives = 29/51 (56%), Gaps = 2/51 (3%)

Query: 7  RKGKPGKGG-GKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSR 56
          R G+ G+GG G G  RGG G R       G GGGGGGGG GGGG     +R
Sbjct: 21 RGGRGGRGGFGGGRGRGG-GFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNR 70



 Score = 38.1 bits (87), Expect = 0.059
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 5/50 (10%)

Query: 6  RRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
          R +G+ G GGG G   GGRGG    S     GG  G G GG  GN+   +
Sbjct: 41 RGRGRGGGGGGGGGGGGGRGGGGFHS-----GGNRGRGRGGKRGNQSGKN 85


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 23/42 (54%), Positives = 25/42 (59%), Gaps = 3/42 (7%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN 50
           G  G GGG G   GGRG       S+GSGGG  G GGGGGG+
Sbjct: 537 GSYGSGGGGG---GGRGSYGSGGSSYGSGGGSYGSGGGGGGH 575



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 21/36 (58%), Positives = 22/36 (61%)

Query: 16  GKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNR 51
           G GS  GG GG      S+GSGGG  G GGGGGG R
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGR 549



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 25/53 (47%), Positives = 26/53 (49%), Gaps = 4/53 (7%)

Query: 1   MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGG----GGGGGG 49
           +S SV R G  G G G G   GG GG        G GG GGGG    G GGGG
Sbjct: 76  ISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGG 128



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 20/46 (43%), Positives = 22/46 (47%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKAS 54
           G  G GGG GS   G     +   S G GGG  GG G GGG+   S
Sbjct: 567 GSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGS 612



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 1/53 (1%)

Query: 9   GKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDG 61
           G  G G   G  RGG GG    S S G G GGG  GG  GG   +S  +   G
Sbjct: 576 GSYGSGSSSGGYRGGSGGGGGGS-SGGRGSGGGSSGGSIGGRGSSSGGVKSSG 627



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 23/45 (51%), Positives = 24/45 (53%), Gaps = 2/45 (4%)

Query: 12  GKGGGK-GSSRGGRGGR-SHASKSHGSGGGGGGGGGGGGGNRKAS 54
           G GGG  GS  GG GGR S+ S     G GGG  G GGGG    S
Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGS 577



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 24/50 (48%), Positives = 26/50 (52%), Gaps = 6/50 (12%)

Query: 12  GKGGGKGSSRGGRGGR-SHASKS-----HGSGGGGGGGGGGGGGNRKASS 55
           G GGG   S GG GG  S+ S S      G  GGGGGG  GG G+   SS
Sbjct: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSS 609



 Score = 39.7 bits (91), Expect = 0.020
 Identities = 22/47 (46%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 8   KGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKAS 54
           +G  G G G G S  G GG S+ S   G GGGGG G  G GG+   S
Sbjct: 518 RGGGGGGYGSGGSSYGSGGGSYGS---GGGGGGGRGSYGSGGSSYGS 561



 Score = 38.5 bits (88), Expect = 0.045
 Identities = 20/38 (52%), Positives = 20/38 (52%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G GG  G   GG G     S   G GGGG GGGG GGG
Sbjct: 105 GGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGG 142



 Score = 38.1 bits (87), Expect = 0.059
 Identities = 19/37 (51%), Positives = 19/37 (51%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGG 48
           G  GG G   GG GG        G GG GGGG GGGG
Sbjct: 102 GGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGG 138



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 19/38 (50%), Positives = 19/38 (50%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGG 49
           G  GG G   GG GG        G GG GGGG GGG G
Sbjct: 107 GGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 21/44 (47%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 12  GKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASS 55
           G GGG G S GGRG  S    S GS GG G   GG   +  +SS
Sbjct: 590 GSGGGGGGSSGGRG--SGGGSSGGSIGGRGSSSGGVKSSGGSSS 631



 Score = 34.7 bits (78), Expect = 0.65
 Identities = 31/74 (41%), Positives = 32/74 (43%), Gaps = 26/74 (35%)

Query: 2   SSSVRRKG-------KPGKGGGKGSSRGGRGGRS----HASKS----------HGSG--- 37
           SSS RR G         G GGG   + GG G RS      SKS           GSG   
Sbjct: 33  SSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGG 92

Query: 38  --GGGGGGGGGGGG 49
             GGGG GGGG GG
Sbjct: 93  GYGGGGFGGGGFGG 106



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 19/49 (38%), Positives = 21/49 (42%)

Query: 2   SSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGN 50
           SSS   +G  G GGG  S   G GG S      G G   GG    GG +
Sbjct: 582 SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSS 630



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 1/55 (1%)

Query: 2   SSSVRRKGKPGKGGGKGSSRGGRGGRSHAS-KSHGSGGGGGGGGGGGGGNRKASS 55
           SS   R G  G GGG    RG  GG S  S    GS  GG    GG    +  S+
Sbjct: 583 SSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVST 637



 Score = 31.2 bits (69), Expect = 7.2
 Identities = 14/27 (51%), Positives = 16/27 (59%)

Query: 28  SHASKSHGSGGGGGGGGGGGGGNRKAS 54
           SH + S G   GGGGGG G GG+   S
Sbjct: 508 SHTTISGGGSRGGGGGGYGSGGSSYGS 534


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,271,323
Number of Sequences: 37866
Number of extensions: 2440855
Number of successful extensions: 29076
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 375
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 16370
Number of HSP's gapped (non-prelim): 6037
length of query: 1386
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1271
effective length of database: 13,892,928
effective search space: 17657911488
effective search space used: 17657911488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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