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Search of human proteins with 38678524
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38678524 opsin 5 isoform 1 [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38678524 opsin 5 isoform 1 [Homo sapiens] 733 0.0
gi|71999146 opsin 5 isoform 2 [Homo sapiens] 381 e-106
gi|5730019 peropsin [Homo sapiens] 167 1e-41
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 159 5e-39
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 152 4e-37
gi|71999131 opsin 3 [Homo sapiens] 142 3e-34
gi|4506527 rhodopsin [Homo sapiens] 126 3e-29
gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H... 124 1e-28
gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ... 124 1e-28
gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa... 122 5e-28
gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s... 109 3e-24
gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s... 103 2e-22
gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s... 103 2e-22
gi|4557859 somatostatin receptor 2 [Homo sapiens] 88 1e-17
gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo s... 85 9e-17
gi|4557857 somatostatin receptor 1 [Homo sapiens] 83 4e-16
gi|149944554 somatostatin receptor 4 [Homo sapiens] 83 4e-16
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 82 1e-15
gi|4557865 somatostatin receptor 5 [Homo sapiens] 80 4e-15
gi|4557861 somatostatin receptor 3 [Homo sapiens] 79 8e-15
gi|4505513 opiate receptor-like 1 [Homo sapiens] 78 1e-14
gi|33286424 opiate receptor-like 1 [Homo sapiens] 78 1e-14
gi|157426873 tachykinin receptor 2 [Homo sapiens] 77 2e-14
gi|5174593 melatonin receptor 1A [Homo sapiens] 77 2e-14
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 75 7e-14
gi|167000885 galanin receptor 1 [Homo sapiens] 75 7e-14
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 75 9e-14
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 75 9e-14
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 74 3e-13
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 74 3e-13
>gi|38678524 opsin 5 isoform 1 [Homo sapiens]
Length = 354
Score = 733 bits (1891), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSR 60
MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSR
Sbjct: 1 MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSR 60
Query: 61 RKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGS 120
RKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGS
Sbjct: 61 RKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGS 120
Query: 121 LITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFG 180
LITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFG
Sbjct: 121 LITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFG 180
Query: 181 TSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRI 240
TSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRI
Sbjct: 181 TSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRI 240
Query: 241 HSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAM 300
HSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAM
Sbjct: 241 HSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAM 300
Query: 301 YNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE 354
YNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
Sbjct: 301 YNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE 354
>gi|71999146 opsin 5 isoform 2 [Homo sapiens]
Length = 189
Score = 381 bits (979), Expect = e-106
Identities = 189/189 (100%), Positives = 189/189 (100%)
Query: 166 MPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAK 225
MPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAK
Sbjct: 1 MPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAK 60
Query: 226 VKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 285
VKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI
Sbjct: 61 VKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 120
Query: 286 QLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSA 345
QLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSA
Sbjct: 121 QLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSA 180
Query: 346 VLEIHEEWE 354
VLEIHEEWE
Sbjct: 181 VLEIHEEWE 189
>gi|5730019 peropsin [Homo sapiens]
Length = 337
Score = 167 bits (424), Expect = 1e-41
Identities = 90/294 (30%), Positives = 152/294 (51%), Gaps = 8/294 (2%)
Query: 20 DGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCD 79
DG F+ E ++VA YL + G++S N VL + + K+ P + INLAV D
Sbjct: 16 DGSVFSQT---EHNIVAT-YLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTD 71
Query: 80 LGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLS 139
+G+S +G P + S W FG+ GC+ Y FFG S+ +T V++DRYL IC
Sbjct: 72 IGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPD 131
Query: 140 YGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVF 199
G + + W FW MP++G Y P+P G +CT++W S +
Sbjct: 132 VGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVS--Y 189
Query: 200 ILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICA 259
+ ++ ++P V+ + Y + +K + + ++ ++ +TK+++++
Sbjct: 190 TMTVIAINFIVPLTVMFYCYYHVTLSIKHHT--TSDCTESLNRDWSDQIDVTKMSVIMIC 247
Query: 260 GFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
FL+AW PY++V +W++FG P IP ++++ L AKS+ YNP IY V + KF
Sbjct: 248 MFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKF 301
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 159 bits (401), Expect = 5e-39
Identities = 90/292 (30%), Positives = 152/292 (52%), Gaps = 13/292 (4%)
Query: 32 ADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTI 91
A G + ++G+ GN V+Y R + PA + INLAV D +S P
Sbjct: 69 AHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFF 128
Query: 92 ISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKIC--YLSYGVWLKRKHA 149
S +W+FG GC +Y + G FG S+IT+TA++LDRYL I ++GV KR+ A
Sbjct: 129 TSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAA 188
Query: 150 YICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLL 209
++ L +W YA W+ P G YVPE TSC+ D+ +V + + + + F
Sbjct: 189 FV-LLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAV--RAYTMLLCCFVFF 245
Query: 210 LPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--------EMKLTKVAMLICAGF 261
LP +I++ Y+ I ++ + + + F + + L E K+ K+ +L+ F
Sbjct: 246 LPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLF 305
Query: 262 LIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
+++W PY+ V++ + G + +S VP ++AK++A++NPIIY + K+
Sbjct: 306 VLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKY 357
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 152 bits (384), Expect = 4e-37
Identities = 92/303 (30%), Positives = 155/303 (51%), Gaps = 24/303 (7%)
Query: 32 ADLVAGFYLTIIGILSTFGNGYVLYMSSR----------RKKKLR-PAEIMTINLAVCDL 80
A G + ++G+ GN V+Y R + + LR PA + INLAV D
Sbjct: 69 AHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDF 128
Query: 81 GISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKIC--YL 138
+S P S +W+FG GC +Y + G FG S+IT+TA++LDRYL I
Sbjct: 129 LMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
Query: 139 SYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQV 198
++GV KR+ A++ L +W YA W+ P G YVPE TSC+ D+ +V +
Sbjct: 189 TFGVASKRRAAFV-LLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAV--RA 245
Query: 199 FILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--------EMKL 250
+ + + F LP +I++ Y+ I ++ + + + F + + L E K+
Sbjct: 246 YTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKM 305
Query: 251 TKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVID 310
K+ +L+ F+++W PY+ V++ + G + +S VP ++AK++A++NPIIY +
Sbjct: 306 AKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITH 365
Query: 311 YKF 313
K+
Sbjct: 366 PKY 368
>gi|71999131 opsin 3 [Homo sapiens]
Length = 402
Score = 142 bits (359), Expect = 3e-34
Identities = 79/271 (29%), Positives = 136/271 (50%), Gaps = 5/271 (1%)
Query: 43 IGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFG 102
IG+L N VL + + ++ P ++ +N+++ DL +S+ G FT +SC + WV+
Sbjct: 51 IGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWD 110
Query: 103 WIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASF 162
+GC W G++G FG S+ T+T ++ +RY+++ + + A+ + IW Y+
Sbjct: 111 TVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARV---INFSWAWRAITYIWLYSLA 167
Query: 163 WTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKI 222
W PL+G Y+ + G CT+DW A+ F+L + CL++P VI Y I
Sbjct: 168 WAGAPLLGWNRYILDVHGLGCTVDWKSKDAN--DSSFVLFLFLGCLVVPLGVIAHCYGHI 225
Query: 223 IAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDS 282
+ ++ ++ E KL K+ L+ FL+ W+PY V+ G
Sbjct: 226 LYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHL 285
Query: 283 IPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
+ +S+V L AKS +YNP+IY + KF
Sbjct: 286 VTPTISIVSYLFAKSNTVYNPVIYVFMIRKF 316
>gi|4506527 rhodopsin [Homo sapiens]
Length = 348
Score = 126 bits (317), Expect = 3e-29
Identities = 76/287 (26%), Positives = 139/287 (48%), Gaps = 5/287 (1%)
Query: 30 WEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPF 89
W+ ++A + +I +L N LY++ + KK P + +NLAV DL + + G
Sbjct: 35 WQFSMLAAYMFLLI-VLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTS 93
Query: 90 TIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHA 149
T+ + +VFG GC G+ G +L ++ ++++RY+ +C HA
Sbjct: 94 TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHA 153
Query: 150 YICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLL 209
+ +A W A PL G Y+PE SC +D++ + V + F++ +
Sbjct: 154 IMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFT 213
Query: 210 LPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYA 269
+P +I F Y +++ V KE A ++ E ++T++ +++ FLI W+PYA
Sbjct: 214 IPMIIIFFCYGQLVFTV----KEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYA 269
Query: 270 VVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACC 316
V+ + + + +P AKSAA+YNP+IY +++ +F C
Sbjct: 270 SVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNC 316
>gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo
sapiens]
Length = 364
Score = 124 bits (311), Expect = 1e-28
Identities = 78/306 (25%), Positives = 146/306 (47%), Gaps = 7/306 (2%)
Query: 39 YLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHR 98
++ + I S F NG VL + + KK P + +NLAV DL +V+ ++++
Sbjct: 59 WMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGY 118
Query: 99 WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWA 158
+V G C G+ G L ++ +S +R++ +C V K A + +A W
Sbjct: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWI 178
Query: 159 YASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFS 218
+A+ WT P+ G Y P TSC D + + G Q +++ ++ C + P ++IV
Sbjct: 179 WAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLC 238
Query: 219 YVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFG 278
Y+++ +++ +K+ S+ E ++T++ +++ F W PYA + ++A
Sbjct: 239 YLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAAN 294
Query: 279 RPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVT 338
++ +P AKSA +YNP+IY ++ +F C L+ KK +G L + +
Sbjct: 295 PGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSAS 351
Query: 339 TVRKSS 344
SS
Sbjct: 352 KTEVSS 357
>gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo
sapiens]
Length = 364
Score = 124 bits (311), Expect = 1e-28
Identities = 78/306 (25%), Positives = 146/306 (47%), Gaps = 7/306 (2%)
Query: 39 YLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHR 98
++ + I S F NG VL + + KK P + +NLAV DL +V+ ++++
Sbjct: 59 WMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGY 118
Query: 99 WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWA 158
+V G C G+ G L ++ +S +R++ +C V K A + +A W
Sbjct: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWI 178
Query: 159 YASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFS 218
+A+ WT P+ G Y P TSC D + + G Q +++ ++ C + P ++IV
Sbjct: 179 WAAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLC 238
Query: 219 YVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFG 278
Y+++ +++ +K+ S+ E ++T++ +++ F W PYA + ++A
Sbjct: 239 YLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAAN 294
Query: 279 RPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVT 338
++ +P AKSA +YNP+IY ++ +F C L+ KK +G L + +
Sbjct: 295 PGYPFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSAS 351
Query: 339 TVRKSS 344
SS
Sbjct: 352 KTEVSS 357
>gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo
sapiens]
Length = 364
Score = 122 bits (306), Expect = 5e-28
Identities = 76/306 (24%), Positives = 147/306 (48%), Gaps = 7/306 (2%)
Query: 39 YLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHR 98
++ + S F NG VL + + KK P + +NLAV DL +V+ +I++
Sbjct: 59 WMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGY 118
Query: 99 WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWA 158
+V G C G+ G L ++ +S +R+L +C V K A + +A W
Sbjct: 119 FVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWI 178
Query: 159 YASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFS 218
+++ WT P+ G Y P TSC D + + G Q +++ ++ C ++P A+I+
Sbjct: 179 WSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLC 238
Query: 219 YVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFG 278
Y+++ +++ +K+ S+ E ++T++ +++ + + W PY + ++A
Sbjct: 239 YLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAAN 294
Query: 279 RPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVT 338
+ ++ +P AKSA +YNP+IY ++ +F C L+ KK +G L + +
Sbjct: 295 PGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSAS 351
Query: 339 TVRKSS 344
SS
Sbjct: 352 KTEVSS 357
>gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo
sapiens]
Length = 348
Score = 109 bits (273), Expect = 3e-24
Identities = 71/298 (23%), Positives = 137/298 (45%), Gaps = 7/298 (2%)
Query: 20 DGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCD 79
DG + W L A F T+ ++ N VL + R KK +P + +N++
Sbjct: 22 DGPQYHIAPVWAFYLQAAFMGTVF-LIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGG 80
Query: 80 LGISVVGK-PFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYL 138
+ + P + SC + +VFG C G+ G G + ++ ++ +RY+ IC
Sbjct: 81 FLLCIFSVFPVFVASCNGY-FVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKP 139
Query: 139 SYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQV 198
KHA + A W + P G ++PE SC DW+ +
Sbjct: 140 FGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSES 199
Query: 199 FILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLIC 258
+ + FC ++P ++I FSY +++ +K+ VA ++ E +++++ +++
Sbjct: 200 YTWFLFIFCFIVPLSLICFSYTQLLRALKA----VAAQQQESATTQKAEREVSRMVVVMV 255
Query: 259 AGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACC 316
F + ++PYA +++ R + ++L +P+ +KSA +YNPIIY ++ +F C
Sbjct: 256 GSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQAC 313
>gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo
sapiens]
Length = 295
Score = 103 bits (258), Expect = 2e-22
Identities = 70/276 (25%), Positives = 123/276 (44%), Gaps = 26/276 (9%)
Query: 34 LVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISV---VGKPFT 90
L G L + + N ++ + + P ++ ++LA+ D GIS+ V +
Sbjct: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSS 76
Query: 91 IISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAY 150
++ RW +G GC+ +G+ GF S+ + A++ RY C S W A
Sbjct: 77 LLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAW---NSAV 133
Query: 151 ICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLL 210
+ +W ++FW +PL+G G Y EP GT CTLD+ ++ F+ + FF +
Sbjct: 134 SLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAM 191
Query: 211 PTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAV 270
P + + SY + + ++ S L++ T A + L+ W PYA+
Sbjct: 192 PLFITITSY--------------SLMEQKLGKSGHLQVNTTLPARTL----LLGWGPYAI 233
Query: 271 VSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIY 306
+ +++ SI +L +VP L+AK N I Y
Sbjct: 234 LYLYAVIADVTSISPKLQMVPALIAKMVPTINAINY 269
>gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo
sapiens]
Length = 291
Score = 103 bits (257), Expect = 2e-22
Identities = 70/273 (25%), Positives = 120/273 (43%), Gaps = 24/273 (8%)
Query: 34 LVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIIS 93
L G L + + N ++ + + P ++ ++LA+ D GIS+ S
Sbjct: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISL-NALVAATS 75
Query: 94 CFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICL 153
RW +G GC+ +G+ GF S+ + A++ RY C S W A +
Sbjct: 76 SLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAW---NSAVSLV 132
Query: 154 AAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTA 213
+W ++FW +PL+G G Y EP GT CTLD+ ++ F+ + FF +P
Sbjct: 133 LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLF 190
Query: 214 VIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSV 273
+ + SY + + ++ S L++ T A + L+ W PYA++ +
Sbjct: 191 ITITSY--------------SLMEQKLGKSGHLQVNTTLPARTL----LLGWGPYAILYL 232
Query: 274 WSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIY 306
++ SI +L +VP L+AK N I Y
Sbjct: 233 YAVIADVTSISPKLQMVPALIAKMVPTINAINY 265
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 87.8 bits (216), Expect = 1e-17
Identities = 74/293 (25%), Positives = 129/293 (44%), Gaps = 26/293 (8%)
Query: 32 ADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTI 91
++ V F ++ I+ GN V+Y+ R K I +NLA+ D + ++G PF
Sbjct: 42 SNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIAD-ELFMLGLPFLA 100
Query: 92 ISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICY-LSYGVWLKRKHAY 150
+ W FG CR S+ +T +S+DRYL + + + W + + A
Sbjct: 101 MQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAK 160
Query: 151 ICLAAIWAYASFWTTMPLVGLGDYVPEPFG-TSCTLDWWLAQASVGGQVFILNILFFCLL 209
+ A+W S +P++ +G +SCT++W ++ FI+ L
Sbjct: 161 MITMAVWG-VSLLVILPIMIYAGLRSNQWGRSSCTINW-PGESGAWYTGFIIYTFILGFL 218
Query: 210 LPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYA 269
+P +I Y+ II KVKSS V S+ S E K+T++ ++ A F+ W+P+
Sbjct: 219 VPLTIICLCYLFIIIKVKSSGIRVG--SSKRKKS---EKKVTRMVSIVVAVFIFCWLPFY 273
Query: 270 VVSVWSAFGRPDSIPIQLSVVPTL---------LAKSAAMYNPIIYQVIDYKF 313
+ +V S+ + +S P L L + + NPI+Y + F
Sbjct: 274 IFNV-------SSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNF 319
>gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo
sapiens]
Length = 253
Score = 85.1 bits (209), Expect = 9e-17
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 6/196 (3%)
Query: 34 LVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIIS 93
L G L + + N ++ + + P ++ ++LA+ D GIS+ S
Sbjct: 17 LAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISL-NALVAATS 75
Query: 94 CFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICL 153
RW +G GC+ +G+ GF S+ + A++ RY C S W A +
Sbjct: 76 SLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAW---NSAVSLV 132
Query: 154 AAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTA 213
+W ++FW +PL+G G Y EP GT CTLD+ ++ F+ + FF +P
Sbjct: 133 LFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDY--SKGDRNFTSFLFTMSFFNFAMPLF 190
Query: 214 VIVFSYVKIIAKVKSS 229
+ + SY + K+ S
Sbjct: 191 ITITSYSLMEQKLGKS 206
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 82.8 bits (203), Expect = 4e-16
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 26/289 (8%)
Query: 34 LVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIIS 93
++ F +++ ++ GN V+Y+ R K I +NLA+ D + ++ PF + S
Sbjct: 59 ILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIAD-ELLMLSVPFLVTS 117
Query: 94 CFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKH-AYIC 152
W FG + CR S+ +T +S+DRY+ + + +R A +
Sbjct: 118 TLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVV 177
Query: 153 LAAIWAYASFWTTMPLVGLGDYVPEPFGT-SCTL------DWWLAQASVGGQVFILNILF 205
+W S +P+V GT +C + WL VG F+L
Sbjct: 178 NLGVWVL-SLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWL----VG---FVLYTFL 229
Query: 206 FCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAW 265
LLP I YV IIAK++ + + A + R S E K+T + M++ F+I W
Sbjct: 230 MGFLLPVGAICLCYVLIIAKMRMVALK-AGWQQRKRS----ERKITLMVMMVVMVFVICW 284
Query: 266 IPYAVVSVWSAFGRPDSIPI-QLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
+P+ VV + + F D + QLSV+ L + + NPI+Y + F
Sbjct: 285 MPFYVVQLVNVFAEQDDATVSQLSVI---LGYANSCANPILYGFLSDNF 330
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 82.8 bits (203), Expect = 4e-16
Identities = 73/306 (23%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 42 IIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVF 101
++ ++ GN V+++ R K I +NLAV D + ++ PF S W F
Sbjct: 56 LVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVAD-ELFMLSVPFVASSAALRHWPF 114
Query: 102 GWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICY-LSYGVWLKRKHAYICLAAIWAYA 160
G + CR S+ +T +S+DRY+ + + L + + A + +W A
Sbjct: 115 GSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWL-A 173
Query: 161 SFWTTMPLVGLGDYVPEPFG--TSCTLDW----WLAQASVGGQVFILNILFFCLLLPTAV 214
S T+P+ D P G +C L W W A VF++ LLP
Sbjct: 174 SLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSA-------VFVVYTFLLGFLLPVLA 226
Query: 215 IVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVW 274
I Y+ I+ K+++ + A + R S E K+T++ +++ F++ W+P+ VV +
Sbjct: 227 IGLCYLLIVGKMRAVALR-AGWQQRRRS----EKKITRLVLMVVVVFVLCWMPFYVVQLL 281
Query: 275 SAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF----------ACCQTGGLKAT 324
+ F S+ ++ V +L+ + + NPI+Y + F CC G
Sbjct: 282 NLF--VTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGA 339
Query: 325 KKKSLE 330
+++ L+
Sbjct: 340 EEEPLD 345
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 81.6 bits (200), Expect = 1e-15
Identities = 61/234 (26%), Positives = 107/234 (45%), Gaps = 12/234 (5%)
Query: 39 YLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHR 98
Y +II +L GN V+++ + K NLAV DL ++ + PFT+
Sbjct: 57 YCSII-LLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE 115
Query: 99 WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWA 158
W G + C +A S IT+T ++LDR+ I Y + ++ +++ + W
Sbjct: 116 WKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESK-ISKRISFLIIGLAWG 174
Query: 159 YASFWTTMPLVGLGDY-----VPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTA 213
++ + PL +Y +P+ +CT W + S+ G V+ L+ L +LP
Sbjct: 175 ISALLAS-PLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLG 233
Query: 214 VIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIP 267
+I FSY +I +K+K+ A D H K TK+ + + F ++W+P
Sbjct: 234 IISFSYTRIWSKLKNHVSPGAAND----HYHQRRQKTTKMLVCVVVVFAVSWLP 283
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 79.7 bits (195), Expect = 4e-15
Identities = 74/269 (27%), Positives = 117/269 (43%), Gaps = 19/269 (7%)
Query: 50 GNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWY 109
GN V+Y+ R K I +NLAV D+ + ++G PF W FG + CR
Sbjct: 57 GNTLVIYVVLRFAKMKTVTNIYILNLAVADV-LYMLGLPFLATQNAASFWPFGPVLCRLV 115
Query: 110 GWAGFFFGCGSLITMTAVSLDRYLKICY-LSYGVWLKRKHAYICLAAIWAYASFWTTMPL 168
S+ +T +S+DRYL + + LS W + + A + AA W S ++PL
Sbjct: 116 MTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVL-SLCMSLPL 174
Query: 169 VGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKS 228
+ D V E G +C W + G VFI+ P VI Y+ I+ KV++
Sbjct: 175 LVFAD-VQE--GGTCNASW-PEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRA 230
Query: 229 SSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAF----GRPDSIP 284
+ V R E K+T++ +++ F W+P+ V++ + P S
Sbjct: 231 AGVRVGCVRRR------SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAG 284
Query: 285 IQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
+ VV A S A NP++Y + F
Sbjct: 285 LYFFVVILSYANSCA--NPVLYGFLSDNF 311
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 78.6 bits (192), Expect = 8e-15
Identities = 77/313 (24%), Positives = 131/313 (41%), Gaps = 17/313 (5%)
Query: 6 TALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKL 65
+A P D L + P + L+ L+ YL ++ ++ GN V+Y+ R
Sbjct: 20 SAWPPDATLGNV--SAGPSPAGLAVSGVLIPLVYL-VVCVVGLLGNSLVIYVVLRHTASP 76
Query: 66 RPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMT 125
+ +NLA+ D + ++G PF W FG + CR S+ +T
Sbjct: 77 SVTNVYILNLALAD-ELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLT 135
Query: 126 AVSLDRYLKICYLSYGV-WLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCT 184
+S+DRYL + + + W A AA+W AS +P+V P G S
Sbjct: 136 VMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWV-ASAVVVLPVVVFSGV---PRGMSTC 191
Query: 185 LDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSH 244
W A+ FI+ P VI Y+ I+ KV+S+ + V +
Sbjct: 192 HMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV--WAPSCQRRR 249
Query: 245 VLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAF----GRPDSIPIQLSVVPTLLAKSAAM 300
E ++T++ + + A F++ W+P+ V+++ + P + VV A S A
Sbjct: 250 RSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCA- 308
Query: 301 YNPIIYQVIDYKF 313
NPI+Y + Y+F
Sbjct: 309 -NPILYGFLSYRF 320
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 78.2 bits (191), Expect = 1e-14
Identities = 85/333 (25%), Positives = 137/333 (41%), Gaps = 51/333 (15%)
Query: 4 NHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGIL------STFGNGYVLYM 57
NH+ LP PH L + S A L G +TI+G+ GN V+Y+
Sbjct: 28 NHSLLP-----PHLLLNA-------SHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYV 75
Query: 58 SSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFG 117
R K I NLA+ D + ++ PF W FG C+ ++
Sbjct: 76 ILRHTKMKTATNIYIFNLALADT-LVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNM 134
Query: 118 CGSLITMTAVSLDRYLKICYLSYGVWLK-RKHAYICLAAIWAYASFWTTMPLVGLGDYVP 176
S T+TA+S+DRY+ IC+ + ++ A AIWA AS +P+ +G
Sbjct: 135 FTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV-VGVPVAIMGSAQV 193
Query: 177 EPFGTSCTL------DWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVK--- 227
E C + D+W G VF + I F ++P VI Y +I +++
Sbjct: 194 EDEEIECLVEIPTPQDYW-------GPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVR 246
Query: 228 --SSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 285
S S+E D + ++T++ +++ A F+ W P V + G S
Sbjct: 247 LLSGSREK---DRNLR-------RITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSET 296
Query: 286 QLSVVP--TLLAKSAAMYNPIIYQVIDYKFACC 316
++++ T L + NPI+Y +D F C
Sbjct: 297 AVAILRFCTALGYVNSCLNPILYAFLDENFKAC 329
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 78.2 bits (191), Expect = 1e-14
Identities = 85/333 (25%), Positives = 137/333 (41%), Gaps = 51/333 (15%)
Query: 4 NHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGIL------STFGNGYVLYM 57
NH+ LP PH L + S A L G +TI+G+ GN V+Y+
Sbjct: 28 NHSLLP-----PHLLLNA-------SHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYV 75
Query: 58 SSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFG 117
R K I NLA+ D + ++ PF W FG C+ ++
Sbjct: 76 ILRHTKMKTATNIYIFNLALADT-LVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNM 134
Query: 118 CGSLITMTAVSLDRYLKICYLSYGVWLK-RKHAYICLAAIWAYASFWTTMPLVGLGDYVP 176
S T+TA+S+DRY+ IC+ + ++ A AIWA AS +P+ +G
Sbjct: 135 FTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV-VGVPVAIMGSAQV 193
Query: 177 EPFGTSCTL------DWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVK--- 227
E C + D+W G VF + I F ++P VI Y +I +++
Sbjct: 194 EDEEIECLVEIPTPQDYW-------GPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVR 246
Query: 228 --SSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPI 285
S S+E D + ++T++ +++ A F+ W P V + G S
Sbjct: 247 LLSGSREK---DRNLR-------RITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSET 296
Query: 286 QLSVVP--TLLAKSAAMYNPIIYQVIDYKFACC 316
++++ T L + NPI+Y +D F C
Sbjct: 297 AVAILRFCTALGYVNSCLNPILYAFLDENFKAC 329
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 77.4 bits (189), Expect = 2e-14
Identities = 72/298 (24%), Positives = 125/298 (41%), Gaps = 26/298 (8%)
Query: 29 SWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKP 88
SW+ L A YL ++ +++ GN V+++ ++ +NLA+ DL ++
Sbjct: 30 SWQLALWATAYLALV-LVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAA 88
Query: 89 FTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKH 148
F + + W FG C + S+ +MTA++ DRY+ I + + L
Sbjct: 89 FNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVH-PFQPRLSAPS 147
Query: 149 AYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASV------GGQVFILN 202
+A IW LV L P+ F ++ T+D + V GG+ +L
Sbjct: 148 TKAVIAGIW----------LVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLY 197
Query: 203 ---ILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEM-KLTKVAMLIC 258
++ LP AV+ +Y +I H + H+ M K K +L+
Sbjct: 198 HLVVIALIYFLPLAVMFVAY-SVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVV 256
Query: 259 AGFLIAWIPYAVVSVWSAFGRP---DSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313
F I W+PY + + +F Q+ + LA S+ MYNPIIY ++++F
Sbjct: 257 LTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRF 314
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 77.0 bits (188), Expect = 2e-14
Identities = 75/315 (23%), Positives = 133/315 (42%), Gaps = 21/315 (6%)
Query: 4 NHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKK 63
N +ALP + P DG ++ SW A +A + I ++ GN V+ R KK
Sbjct: 4 NGSALPNASQ-PVLRGDG----ARPSWLASALACVLIFTI-VVDILGNLLVILSVYRNKK 57
Query: 64 KLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLIT 123
I ++LAV DL +++ P ++S F + W G++ C+ G+ GS+
Sbjct: 58 LRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFN 117
Query: 124 MTAVSLDRYLKICY-LSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTS 182
+T ++++RY IC+ L Y K++ + IW + +P + G +P S
Sbjct: 118 ITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIW-LLTLAAVLPNLRAGTLQYDPRIYS 176
Query: 183 CTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHS 242
CT A + + ++ F L+P +++F Y++I V + V R
Sbjct: 177 CTF------AQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVK--PDRKPK 228
Query: 243 SHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDS----IPIQLSVVPTLLAKSA 298
+ + ++ F I W P + + + P S IP L V +A
Sbjct: 229 LKPQDFRNFVTMFVVFVLFAICWAPLNFIGL-AVASDPASMVPRIPEWLFVASYYMAYFN 287
Query: 299 AMYNPIIYQVIDYKF 313
+ N IIY +++ F
Sbjct: 288 SCLNAIIYGLLNQNF 302
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 75.5 bits (184), Expect = 7e-14
Identities = 74/344 (21%), Positives = 135/344 (39%), Gaps = 25/344 (7%)
Query: 29 SWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKP 88
+W+ L A Y T+I + S GN V+++ K+ +NLA + ++
Sbjct: 29 AWQIVLWAAAY-TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTV 87
Query: 89 FTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKH 148
+ W +G C+++ + S+ +MTAV+ DRY+ I + L
Sbjct: 88 VNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIH-PLQPRLSATA 146
Query: 149 AYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCL 208
+ + IW A P P C ++W + +V+ + +
Sbjct: 147 TKVVICVIWVLA-LLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205
Query: 209 LLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPY 268
LP VI ++Y ++ +S+ R H + K+ K+ +++ F I W+P+
Sbjct: 206 FLPLLVIGYAYT-VVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPF 264
Query: 269 AVVSVWSAFGRPD----SIPIQLSVVPTLLAKSAAMYNPIIYQVID--------YKFACC 316
+ + + PD Q+ + LA S+ MYNPIIY ++ + F CC
Sbjct: 265 HIFFL-LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCC 323
Query: 317 Q--TGG------LKATKKKSLEGFRLHTVTTVRKSSAVLEIHEE 352
+ G +K+T+ +G S V+ HEE
Sbjct: 324 PFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEE 367
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 75.5 bits (184), Expect = 7e-14
Identities = 62/277 (22%), Positives = 115/277 (41%), Gaps = 13/277 (4%)
Query: 42 IIGILSTFGNGYVLYMSSRRK--KKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRW 99
+I L GN V+ + +R K K + +NL++ DL + PF W
Sbjct: 42 LIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTW 101
Query: 100 VFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLK-RKHAYICLAAIWA 158
V G C++ + S+ T+ A+S+DRY+ I + L+ ++A + + IWA
Sbjct: 102 VLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWA 161
Query: 159 YASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFS 218
+ + G + P + + W + +++ F LLP +I F
Sbjct: 162 LSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHK--KAYVVCTFVFGYLLPLLLICFC 219
Query: 219 YVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFG 278
Y K++ + K ++ S + K + +++ F I+W+P+ ++ +W+ FG
Sbjct: 220 YAKVLNHLHKKLKNMSK------KSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFG 273
Query: 279 RPDSIPIQ--LSVVPTLLAKSAAMYNPIIYQVIDYKF 313
P + LA S + NPIIY + F
Sbjct: 274 VFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENF 310
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 75.1 bits (183), Expect = 9e-14
Identities = 89/330 (26%), Positives = 150/330 (45%), Gaps = 45/330 (13%)
Query: 41 TIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHR-- 98
++I ++ FGNG+VLY+ + K ++ INLAV DL + V P ++ + H+
Sbjct: 31 SMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADL-LCVCTLPLRVV-YYVHKGI 88
Query: 99 WVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWL--KRKHAYICLAAI 156
W+FG CR +A + S+ MTA+S R + I + + L ++K ++C+ I
Sbjct: 89 WLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCV-GI 147
Query: 157 WAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIV 216
W + T+ P + E T C Q V LF ++P +I+
Sbjct: 148 WIFV-ILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIII 206
Query: 217 FSYVKIIAKV--KSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVV-SV 273
Y II + KS K + SSH K + M++ A FL++++PY + ++
Sbjct: 207 VCYTMIILTLLKKSMKKNL--------SSH---KKAIGMIMVVTAAFLVSFMPYHIQRTI 255
Query: 274 WSAFGRPDSIP------IQLSVVPTL-LAKSAAMYNPIIYQVIDYKFACCQTGGLKATKK 326
F ++ P +Q SVV TL LA S ++P++Y F +
Sbjct: 256 HLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNF------------R 303
Query: 327 KSLEGFRLHTVTTV----RKSSAVLEIHEE 352
K L FR H++++V RK +++ E EE
Sbjct: 304 KRLSTFRKHSLSSVTYVPRKKASLPEKGEE 333
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 75.1 bits (183), Expect = 9e-14
Identities = 69/282 (24%), Positives = 117/282 (41%), Gaps = 34/282 (12%)
Query: 45 ILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWI 104
+L+ FGN V+ K+ P + +LA D + V PF+ + W FG
Sbjct: 44 VLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDS 103
Query: 105 GCRWYGWAGFFFGCGSLITMTAVSLDRYLKIC-YLSYGVWLKRKHAYICLAAIW------ 157
C+++ F SL + +S+DRY+ + L+Y + IC+ W
Sbjct: 104 YCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTY 163
Query: 158 AYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILN-----ILFFCLLLPT 212
+++ F+T G+ + V +A VGG LN + F +P
Sbjct: 164 SFSIFYTGANEEGIEELV-------------VALTCVGGCQAPLNQNWVLLCFLLFFIPN 210
Query: 213 AVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSH--------VLEMKLTKVAMLICAGFLIA 264
+VF Y KI K ++++ S+ SS E K K + A FL++
Sbjct: 211 VAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVS 270
Query: 265 WIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIY 306
W+PY V +V A+ + P ++ + ++AM NP+IY
Sbjct: 271 WLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAM-NPLIY 311
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 73.6 bits (179), Expect = 3e-13
Identities = 62/282 (21%), Positives = 114/282 (40%), Gaps = 9/282 (3%)
Query: 29 SWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKP 88
+W+ L A Y T+I + S GN V+++ K+ +NLA + ++
Sbjct: 29 AWQIVLWAAAY-TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTV 87
Query: 89 FTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKH 148
+ W +G C+++ + S+ +MTAV+ DRY+ I + L
Sbjct: 88 VNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIH-PLQPRLSATA 146
Query: 149 AYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCL 208
+ + IW A P P C ++W + +V+ + +
Sbjct: 147 TKVVICVIWVLA-LLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIY 205
Query: 209 LLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPY 268
LP VI ++Y ++ +S+ R H + K+ K+ +++ F I W+P+
Sbjct: 206 FLPLLVIGYAYT-VVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPF 264
Query: 269 AVVSVWSAFGRPD----SIPIQLSVVPTLLAKSAAMYNPIIY 306
+ + + PD Q+ + LA S+ MYNPIIY
Sbjct: 265 HIFFL-LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 73.6 bits (179), Expect = 3e-13
Identities = 66/283 (23%), Positives = 118/283 (41%), Gaps = 16/283 (5%)
Query: 41 TIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWV 100
+++ ++ GN V+++ R K I NLA+ D ++ PF + W
Sbjct: 67 SVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTT-MPFQSTVYLMNSWP 125
Query: 101 FGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICY----LSYGVWLKRKHAYICLAAI 156
FG + C+ ++ S+ T+T +S+DRY+ +C+ L + LK K IC I
Sbjct: 126 FGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINIC---I 182
Query: 157 WAYASFWTTMPLVGLGDYVPEPFGT-SCTLDWWLAQASVGGQVFILNILFFCLLLPTAVI 215
W +S +V G V E C+L + S + + F ++P +I
Sbjct: 183 WLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLII 242
Query: 216 VFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWS 275
+ Y +I ++KS V L ++T++ +++ A F++ W P + +
Sbjct: 243 IVCYTLMILRLKS----VRLLSGSREKDRNLR-RITRLVLVVVAVFVVCWTPIHIFILVE 297
Query: 276 AFGRPDSIPIQLS--VVPTLLAKSAAMYNPIIYQVIDYKFACC 316
A G LS L + + NPI+Y +D F C
Sbjct: 298 ALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRC 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.140 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,226,926
Number of Sequences: 37866
Number of extensions: 550814
Number of successful extensions: 2245
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 307
Number of HSP's that attempted gapping in prelim test: 1620
Number of HSP's gapped (non-prelim): 599
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.