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Search of human proteins with 38505226
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38505226 E2F family member 8 [Homo sapiens]
(867 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38505226 E2F family member 8 [Homo sapiens] 1719 0.0
gi|145580626 E2F transcription factor 7 [Homo sapiens] 390 e-108
gi|4503433 E2F transcription factor 3 [Homo sapiens] 60 7e-09
gi|12669911 E2F transcription factor 1 [Homo sapiens] 55 3e-07
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 54 8e-07
gi|4758226 E2F transcription factor 2 [Homo sapiens] 54 8e-07
gi|12669915 E2F transcription factor 4 [Homo sapiens] 53 1e-06
gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens] 52 2e-06
gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens] 52 2e-06
gi|45387951 transmembrane protein 108 [Homo sapiens] 52 3e-06
gi|210147493 transmembrane protein 108 [Homo sapiens] 52 3e-06
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] 51 4e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 50 1e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 47 6e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 47 6e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 47 6e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 47 6e-05
gi|109637795 E2F transcription factor 6 [Homo sapiens] 47 6e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 47 1e-04
gi|91982772 mucin 17 [Homo sapiens] 47 1e-04
gi|83367077 mucin 16 [Homo sapiens] 45 2e-04
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 45 2e-04
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 45 2e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 45 3e-04
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 44 6e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 6e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 44 6e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 44 8e-04
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 44 8e-04
gi|151301154 mucin 6, gastric [Homo sapiens] 44 8e-04
>gi|38505226 E2F family member 8 [Homo sapiens]
Length = 867
Score = 1719 bits (4451), Expect = 0.0
Identities = 867/867 (100%), Positives = 867/867 (100%)
Query: 1 MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPT 60
MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPT
Sbjct: 1 MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPT 60
Query: 61 ANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGL 120
ANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGL
Sbjct: 61 ANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGL 120
Query: 121 LCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTW 180
LCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTW
Sbjct: 121 LCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTW 180
Query: 181 HGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGH 240
HGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGH
Sbjct: 181 HGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGH 240
Query: 241 PDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHV 300
PDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHV
Sbjct: 241 PDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHV 300
Query: 301 EDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPV 360
EDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPV
Sbjct: 301 EDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPV 360
Query: 361 IHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIK 420
IHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIK
Sbjct: 361 IHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIK 420
Query: 421 TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVN 480
TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVN
Sbjct: 421 TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVN 480
Query: 481 AEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGL 540
AEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGL
Sbjct: 481 AEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGL 540
Query: 541 SPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAG 600
SPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAG
Sbjct: 541 SPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAG 600
Query: 601 ERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENS 660
ERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENS
Sbjct: 601 ERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENS 660
Query: 661 SALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALAS 720
SALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALAS
Sbjct: 661 SALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALAS 720
Query: 721 SHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQG 780
SHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQG
Sbjct: 721 SHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQG 780
Query: 781 RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMD 840
RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMD
Sbjct: 781 RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMD 840
Query: 841 FEGANKTSLGTLFVPQRKLEVSTEDVH 867
FEGANKTSLGTLFVPQRKLEVSTEDVH
Sbjct: 841 FEGANKTSLGTLFVPQRKLEVSTEDVH 867
>gi|145580626 E2F transcription factor 7 [Homo sapiens]
Length = 911
Score = 390 bits (1002), Expect = e-108
Identities = 338/947 (35%), Positives = 458/947 (48%), Gaps = 160/947 (16%)
Query: 4 EKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANL 63
+KEN+F + R KTP+K + P+ P+T P K + Q EPWTPTANL
Sbjct: 30 QKENIFVD-RSRMAPKTPIKNEPIDLSKQKKFTPERNPIT-PVKFVDRQQAEPWTPTANL 87
Query: 64 KMLISAVSPEIRNRDQKRGLFDNRSGLPEA-KDCIHEHLSGD----EFEKSQPSRKEKSL 118
KMLISA SP+IR+R++K+GLF +A D + + GD EFEK +PSRK+KSL
Sbjct: 88 KMLISAASPDIRDREKKKGLFRPIENKDDAFTDSLQLDVVGDSAVDEFEKQRPSRKQKSL 147
Query: 119 GLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRY 178
GLLC KFLARYP+YP I LDEVA L VERRRIYDIVNVLESLH+VSR+AKN+Y
Sbjct: 148 GLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQY 207
Query: 179 TWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPN 238
WHGRH+L KTL L+ +GEE KY EQ+ +++KE + + Y + + G
Sbjct: 208 GWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELD-----LIDYKFGE---RKKDGDP 259
Query: 239 GHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGED 298
+ ++ + ++S NSRKDKSLR+MSQKFVMLFLVS +IV+L+VAAKILI E+
Sbjct: 260 DSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILI-EE 318
Query: 299 HVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSS 358
+ D SKFKTK+RRLYDIANVL+SL LIKKVHVTEERGRKPAFKW GP
Sbjct: 319 SQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGP---------- 368
Query: 359 PVIHFTPSDLEVRRSSKENCAKNLFSTRG------KPNFTRHPSLIKLVKSIESDRRKIN 412
+ F+ SD E+ S + T G K RH S V++ E +RK+N
Sbjct: 369 --VDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGS-FNTVQASERIQRKVN 425
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
S PSSP + Q S + ++ LAA+ + ++E+ S K + S PV
Sbjct: 426 SEPSSPYR-----EEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPV 480
Query: 473 APLDPPVNAEMELTAPSLIQPL------------------GMVPLIPSPLSSAVPLILPQ 514
AP P ++ + E L P+ G V + + +SAV + P
Sbjct: 481 APF-PVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPA 539
Query: 515 APSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKAS 574
+G QP P L + A+GS D D S +
Sbjct: 540 LLAG-------QPL----VYVPSASLFMLYGSLQEGPASGSGSERD--------DRSSEA 580
Query: 575 ASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSG--SKKKFKEDLKGLENVSAT 632
+T S P+ +++ + R + E +KR S + G S K+ + S
Sbjct: 581 PATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPK 640
Query: 633 LFPSGYLIPLTQCSSLG-------------AESILS---------------GKENSSALS 664
+ IPL G A S++S KEN S
Sbjct: 641 TMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKE 700
Query: 665 PNHRIY---SSP--IAGVIPVTSSELT-------AVNFPSFHVTPLKLMVSPTSVAAVPV 712
P+ Y SP + G + S T + PSF V P ++ SP P+
Sbjct: 701 PSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSV-PCMVLPSP------PL 753
Query: 713 GNSPALAS-SHPVPIQN-----PSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIE 766
G P L S + P P+ + P++ VNF+L LG I+ QL P + + P S +
Sbjct: 754 GPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIA---QLLVGPTAVVNPKSSTLP 810
Query: 767 SVNVAPENAGTQQGRATNYDSPVPGQS-----QPN-----GQSVAVTGA-QQPVPVTPKG 815
S + P+ Q + + SPV +S QP G V+V Q PVPVTPK
Sbjct: 811 SAD--PQ----LQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKS 864
Query: 816 SQLV-AESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEV 861
Q E+FF+TPG P + N +S QR+LE+
Sbjct: 865 IQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSS------AQRRLEI 905
>gi|4503433 E2F transcription factor 3 [Homo sapiens]
Length = 465
Score = 60.5 bits (145), Expect = 7e-09
Identities = 36/104 (34%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 109 SQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLH 168
S+ +R + SLGLL KF+ P+ ++ L++ AE L V++RRIYDI NVLE +H
Sbjct: 174 SEKTRYDTSLGLLTKKFIQLLSQSPDGVLD----LNKAAEVLKVQKRRIYDITNVLEGIH 229
Query: 169 MVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKK 212
++ + +KN W G +L++ G L +K ++ +KK
Sbjct: 230 LIKKKSKNNVQWMG-CSLSEDGGMLAQCQGLSKEVTELSQEEKK 272
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 14/77 (18%)
Query: 254 RAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIR 313
++ S +R D SL ++++KF+ L S ++ L AA++L K + R
Sbjct: 171 KSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVL--------------KVQKR 216
Query: 314 RLYDIANVLSSLDLIKK 330
R+YDI NVL + LIKK
Sbjct: 217 RIYDITNVLEGIHLIKK 233
>gi|12669911 E2F transcription factor 1 [Homo sapiens]
Length = 437
Score = 55.1 bits (131), Expect = 3e-07
Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 12/112 (10%)
Query: 110 QPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHM 169
+ SR E SL L +FL + + V+ L+ AE L V++RRIYDI NVLE + +
Sbjct: 124 EKSRYETSLNLTTKRFLELLSHSADGVVD----LNWAAEVLKVQKRRIYDITNVLEGIQL 179
Query: 170 VSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFI 221
+++ +KN W G H G L+ + ++ + + +E EQ+ D +
Sbjct: 180 IAKKSKNHIQWLGSHTTVGVGGRLEGLTQD--------LRQLQESEQQLDHL 223
Score = 40.0 bits (92), Expect = 0.009
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 14/82 (17%)
Query: 249 PGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKF 308
PG ++ SR + SL + +++F+ L S +V L AA++L
Sbjct: 115 PGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVL-------------- 160
Query: 309 KTKIRRLYDIANVLSSLDLIKK 330
K + RR+YDI NVL + LI K
Sbjct: 161 KVQKRRIYDITNVLEGIQLIAK 182
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 53.5 bits (127), Expect = 8e-07
Identities = 102/431 (23%), Positives = 153/431 (35%), Gaps = 64/431 (14%)
Query: 468 PCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIP-----SPLSSAVPLILPQAPSGPSYA 522
P PV P D PV +P + P++P SP+ S P P P P+ +
Sbjct: 1315 PVVPVTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPADS 1374
Query: 523 IYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSL 582
+ T A + P TT S+ + D DT + ++ G +
Sbjct: 1375 PVVPVTSADSPLIP--------LTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPV 1426
Query: 583 LPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPL 642
+P G PA GS S G L VS P G ++P+
Sbjct: 1427 VPVTPA-GDPIVPVTPADTPGSPVTSA---DGPVVPVTTPDGPLVPVSP---PDGPVVPV 1479
Query: 643 TQCSSLGAESILSGKENSSALSPNHRIYSSPIAG--VIPVTSSEL-----TAVNFPSFHV 695
T + + + I A V+PVT +++ T N P HV
Sbjct: 1480 TSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHV 1539
Query: 696 TP-----------------------LKLMVSPTSVAAVP-VGNSPA----LASSHPVPIQ 727
T L + VSPT VP + + P +A S +P+
Sbjct: 1540 TSADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVT 1599
Query: 728 NPSSAIVNFTLQHLGLISPNVQLS-----ASPGSG-IVPVSPRIESVNVAPENAGTQQGR 781
S +V TL G + P + +P +G + PV+P ++ V+ A
Sbjct: 1600 PADSTVVPVTLAD-GPVVPVTSVDIPVVPVTPANGPVAPVTP-VDDPVVSVNPADGSVVP 1657
Query: 782 ATNYDSPVPGQSQPNGQSVAVTGAQQP-VPVTPKGSQLVAESFFRTPGGPTKPTSSSCMD 840
T+ D PV + +G V VT A P VPVTP S +V + +P P P S +
Sbjct: 1658 VTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTPADSPVVP 1717
Query: 841 FEGANKTSLGT 851
A+ S G+
Sbjct: 1718 VTSADTDSPGS 1728
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/168 (30%), Positives = 78/168 (46%), Gaps = 20/168 (11%)
Query: 677 VIPVTSSE-----LTAVNFPSFHVTPLKLMVSPTS----VAAVPVGNSPAL----ASSHP 723
V+PVTS++ +T + P VTP+ +VS T+ V V +SP + A S
Sbjct: 1257 VVPVTSADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPV 1316
Query: 724 VPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRAT 783
VP+ +V T SP V ++ + IVPV+P +S V+ A + T
Sbjct: 1317 VPVTPADGPVVPVTSAD----SPFVPVTPADDP-IVPVTPA-DSPIVSVTPAESPAIPVT 1370
Query: 784 NYDSPVPGQSQPNGQSVAVTGA-QQPVPVTPKGSQLVAESFFRTPGGP 830
DSPV + + + +T A + VPVTP G +V + TPG P
Sbjct: 1371 PADSPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSP 1418
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/167 (30%), Positives = 71/167 (42%), Gaps = 15/167 (8%)
Query: 677 VIPVTSSELTAV-----NFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHP-VPIQNPS 730
V+PVTS+++ V + P VT V+P S A PV P + P +P+
Sbjct: 467 VVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPV--VPVTPADSPFIPVTTAD 524
Query: 731 SAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVP 790
IV T ++S V + SP + P I V V P N T+ DSP
Sbjct: 525 DLIVPVTPADSPVLS--VTPAESPAIPVTPADSPI--VPVTPANGPVVP--VTSADSPFV 578
Query: 791 GQSQPNGQSVAVTGAQQPV-PVTPKGSQLVAESFFRTPGGPTKPTSS 836
+G V VT A PV PVTP S +++ + +P P P S
Sbjct: 579 PVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADS 625
Score = 45.4 bits (106), Expect = 2e-04
Identities = 54/171 (31%), Positives = 74/171 (43%), Gaps = 28/171 (16%)
Query: 679 PVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPV-----GNSPAL----ASSHPVPIQNP 729
PV S +T+ + P F VTP V P + A VPV G+ P + A S VP+ +
Sbjct: 2533 PVVS--VTSDDSPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSA 2590
Query: 730 SSAIVNFTLQHLGL--ISP--NVQLSASPG-SGIVPVSPRIESVNVAPENAGTQQGRATN 784
S + T + +SP ++ + +PG S +VPVSP V + T
Sbjct: 2591 DSPVFPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSPADSPVVL-----------VTP 2639
Query: 785 YDSPVPGQSQPNGQSVAVTGAQQP-VPVTPKGSQLVAESFFRTPGGPTKPT 834
D PV + NG V VT A P VPV P +V +S P PT
Sbjct: 2640 ADGPVVPVTPANGPVVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPT 2690
Score = 45.1 bits (105), Expect = 3e-04
Identities = 94/435 (21%), Positives = 149/435 (34%), Gaps = 70/435 (16%)
Query: 468 PCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIP--------SPLSSAVPLILPQAPSGP 519
P PV P D P+ + +P++ P++P SP+++A I+P +G
Sbjct: 987 PFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGD 1046
Query: 520 SYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAAN-DTSKASASTR 578
VT G P V T + D + D A S+
Sbjct: 1047 PIVPVTPADTPGSPVTSADG--PVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSA 1104
Query: 579 PGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGY 638
G ++P G P S ++ + + F V+ P
Sbjct: 1105 DGPVVPVTSADG-------PVAPVSSADGPVVPVTPADSPFIP-------VTTADDP--- 1147
Query: 639 LIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAG--VIPVTSSELTAVNFPSFHVT 696
++P+T S L+ + + P A V+PV+S++ V P
Sbjct: 1148 IVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFV--PVIPAD 1205
Query: 697 PLKLMVSPTSVAAVPVGN---------------SPALASSHPVPIQNPSSAIVNFTLQHL 741
L ++ S T V VPV S +A S +P+ S +V T
Sbjct: 1206 GLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADS 1265
Query: 742 GLISPNVQLSASPGSGIVPVSPRIESVN-----VAPENAGTQQGRATNYDSPVPGQSQPN 796
++ V + SP + PV P + V A + T+ DSPV + +
Sbjct: 1266 PVVP--VTPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTPAD 1323
Query: 797 GQSVAVTGAQQP-----------VPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGAN 845
G V VT A P VPVTP S +V+ + +P P P S + A+
Sbjct: 1324 GPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSAD 1383
Query: 846 K-----TSLGTLFVP 855
T+ G+ VP
Sbjct: 1384 SPLIPLTTAGSRVVP 1398
Score = 44.3 bits (103), Expect = 5e-04
Identities = 56/209 (26%), Positives = 83/209 (39%), Gaps = 36/209 (17%)
Query: 677 VIPVTSSE-----LTAVNFPSFHVTPLK---LMVSPTSVAAVPV--GNSPAL----ASSH 722
V+PVT ++ + + + P VTP + V+P VPV +SP + A
Sbjct: 377 VVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGR 436
Query: 723 PVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRA 782
VP+ IV T +P ++++ G + S I V V P +
Sbjct: 437 VVPVTAAGDPIVPVTPAD----TPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVP--V 490
Query: 783 TNYDSPVPGQSQPNGQSVAVTGAQQP-----------VPVTPKGSQLVAESFFRTPGGPT 831
T+ D PV S +G V VT A P VPVTP S +++ + +P P
Sbjct: 491 TSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPV 550
Query: 832 KPTSSSCMDFEGAN-----KTSLGTLFVP 855
P S + AN TS + FVP
Sbjct: 551 TPADSPIVPVTPANGPVVPVTSADSPFVP 579
Score = 44.3 bits (103), Expect = 5e-04
Identities = 55/186 (29%), Positives = 77/186 (41%), Gaps = 20/186 (10%)
Query: 677 VIPVTSSE-----LTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHP-VPIQNPS 730
V+PVT ++ +T+ + P VTP P + A PV P + P VP+
Sbjct: 908 VVPVTPTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPV--VPFTPADDPIVPVTPAD 965
Query: 731 SAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPV- 789
S +V+ T G + P AS S VPV+P + + V+ A + T DSPV
Sbjct: 966 SPVVSVTPAD-GPVVP----VASADSPFVPVTPADDPI-VSVTPAESPAIPVTQADSPVV 1019
Query: 790 PGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSL 849
P S S T + VPVT G +V + TPG P + TS
Sbjct: 1020 PVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPV-----TSA 1074
Query: 850 GTLFVP 855
+ FVP
Sbjct: 1075 DSPFVP 1080
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/174 (28%), Positives = 69/174 (39%), Gaps = 13/174 (7%)
Query: 672 SPIAGVIPVTSSEL--TAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNP 729
SP+ V P S+ + T + P HVTP V P + A PV + A S VP+
Sbjct: 186 SPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVV-TVASTDSPVVPVTPA 244
Query: 730 SSAIVNFTLQHLGLI------SPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRAT 783
IV T + SP V + + G +V S + V V P N A
Sbjct: 245 DDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFA- 303
Query: 784 NYDSPVPGQSQPNGQSVAVTGAQQP-VPVTPKGSQLVAESFFRTPGGPTKPTSS 836
D + V+VT A P VPVTP S +++ + +P P P S
Sbjct: 304 --DETIXXXXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADS 355
Score = 42.7 bits (99), Expect = 0.001
Identities = 55/195 (28%), Positives = 74/195 (37%), Gaps = 39/195 (20%)
Query: 677 VIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNF 736
VIPVT +E P+ VTP V P + A PV P A S VP+ S ++
Sbjct: 1996 VIPVTPAES-----PAIPVTPTDSPVVPVTSADSPV--IPVTADSPFVPVTPADSPVIPV 2048
Query: 737 TLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPN 796
T P +VPV+P I+ V T +SPV + +
Sbjct: 2049 T---------------PPDDLVVPVTP-IDCPVVPVTLVDCPVVSVTPANSPVDPVTPAD 2092
Query: 797 GQSVAVTGAQQPV-----------PVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGAN 845
G V VT A PV PVTP S +V+ + +P P P S + A+
Sbjct: 2093 GPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVASAD 2152
Query: 846 K-----TSLGTLFVP 855
T T+ VP
Sbjct: 2153 SPVVPVTPADTVVVP 2167
Score = 42.4 bits (98), Expect = 0.002
Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 24/189 (12%)
Query: 677 VIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPV-----GNSPAL----ASSHPVPIQ 727
V+PVTS++ P VTP +V P + A P+ +SP + A S +P+
Sbjct: 1655 VVPVTSADC-----PVVPVTPADGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVT 1709
Query: 728 NPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDS 787
S +V T SP ++++ G +VPV+ +S+ V A T+ D
Sbjct: 1710 PADSPVVPVTSADTD--SPGSPVTSADGP-VVPVTSA-DSLPVPVTPADGPVVPVTSADG 1765
Query: 788 PVPGQSQPNGQSVAVTGAQQP-VPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANK 846
PV S +G V VT A P VPVT V + +P P P + +
Sbjct: 1766 PVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPV----- 1820
Query: 847 TSLGTLFVP 855
TS + FVP
Sbjct: 1821 TSADSPFVP 1829
Score = 41.6 bits (96), Expect = 0.003
Identities = 106/434 (24%), Positives = 161/434 (37%), Gaps = 89/434 (20%)
Query: 467 GPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIP-----SPLSSAVPLILPQAPSGPSY 521
GP PV P D PV +P L L P +P SP+ P P P +
Sbjct: 585 GPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASAD 644
Query: 522 AIYLQPTQAHQ---SVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTR 578
+ ++ T A SVTP + SP + T + S D +T
Sbjct: 645 SPFVPVTPADDPIVSVTPAE--SPAIPVTQADSPVVPVTSADRPV---------IPVTTA 693
Query: 579 PGSLLPAPERQGAKSRTREPAGERGSKRAS----MLEDSGSKKKFKEDLKGLENVSATLF 634
G ++P G PA GS S ++ + + F V T
Sbjct: 694 DGRIVPV-TAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPF---------VPVTP- 742
Query: 635 PSGYLIPLTQCSSLGAESILSGKEN-----SSALSPNHRIYSS--PIAGV---------I 678
P G ++P+T S+ G + +S + +SA P + S+ P+ V +
Sbjct: 743 PDGPVVPVT--SADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAV 800
Query: 679 PVTSSE-----LTAVNFPSFHVTPLK---LMVSPTSVAAVPVGNS-----PALASSHPVP 725
PVTS++ + + P VTP + V+P + VPV ++ P + + PV
Sbjct: 801 PVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVV 860
Query: 726 IQNPSSAIV---------------NFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNV 770
+ + + +V + T+ L V P +VPV+P V
Sbjct: 861 VDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTP--TDCPV 918
Query: 771 AP-ENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQP-VPVTPKGSQLVAESFFRTPG 828
AP +A T DSP + +G V T A P VPVTP S +V+ TP
Sbjct: 919 APVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSV----TPA 974
Query: 829 -GPTKPTSSSCMDF 841
GP P +S+ F
Sbjct: 975 DGPVVPVASADSPF 988
Score = 40.8 bits (94), Expect = 0.005
Identities = 47/168 (27%), Positives = 70/168 (41%), Gaps = 28/168 (16%)
Query: 677 VIPVTSSE-----LTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPV-PIQNPS 730
V+PV S++ +T + P VTP + P + A PV P ++ PV P+
Sbjct: 978 VVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPV--VPVTSADRPVSPVTTAD 1035
Query: 731 SAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVP 790
IV T + G IVPV+P ++ +A T+ DSP
Sbjct: 1036 GRIVPVT---------------AAGDPIVPVTPA-DTPGSPVTSADGPVVPVTSADSPFV 1079
Query: 791 GQSQPNGQSVAVTGAQQPV-PVTPKGSQLVAESFFRTPGGPTKPTSSS 837
+ P+G V VT A PV PV+ +V + + GP P SS+
Sbjct: 1080 PVTPPDGPVVPVTSADGPVAPVSSADGPVVPVT---SADGPVAPVSSA 1124
Score = 40.4 bits (93), Expect = 0.007
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 12/153 (7%)
Query: 677 VIPVTSSE-----LTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSS 731
V PVT ++ +T + P F V+P V P + A +PV P A+ VP+ + S
Sbjct: 2285 VFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVPP-ANGSVVPVTSAGS 2343
Query: 732 AIVNFT----LQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDS 787
V L L + + + SP GI PV + V+ + + T DS
Sbjct: 2344 PFVPIIPADGLVVLDSSTDVLVVLVSPTDGI-PVPDLADDPVVSVTTSDSPVIPVTPTDS 2402
Query: 788 PVPGQSQPNGQSVAVTGAQQP-VPVTPKGSQLV 819
PV + +G V VT P VPVTP S ++
Sbjct: 2403 PVVPVAPADGPVVPVTSVDSPVVPVTPADSPVI 2435
Score = 38.9 bits (89), Expect = 0.021
Identities = 50/166 (30%), Positives = 68/166 (40%), Gaps = 33/166 (19%)
Query: 677 VIPVTSSEL-----TAVNFPSFHVTPLKLMVSP-TSVAAVPVGNSPALASSHPVPIQNPS 730
V+PVT++++ T+ + P VTP +V P TS +V V +PA VP+
Sbjct: 2464 VVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSADSVVVPATPA--DCPLVPVDPAD 2521
Query: 731 SAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVP 790
S IV FT ++S S S + PV+P SV V AG T D PV
Sbjct: 2522 SPIVLFTPYDNPVVSVT-----SDDSPVFPVTPADSSV-VPVTPAGVPVVPVTPGDGPV- 2574
Query: 791 GQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSS 836
VPVTP S +V + +P P P S
Sbjct: 2575 ------------------VPVTPADSLVVPVTSADSPVFPVTPADS 2602
Score = 35.8 bits (81), Expect = 0.18
Identities = 48/159 (30%), Positives = 68/159 (42%), Gaps = 24/159 (15%)
Query: 677 VIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHP-VPIQNPSSAIVN 735
V+PVTS V+ P VTP V P + PV P + P VP+ + S IV+
Sbjct: 1896 VVPVTS-----VDNPVVPVTPADNPVIPVTPVDDPV--VPVTPADDPIVPVTSADSPIVS 1948
Query: 736 FTLQHLGLI------SPNVQLSASPGSGIVPVSPR-IESVNVAPEN--------AGTQQG 780
T + SP + + AS S +VPV+P + V V P + A +
Sbjct: 1949 VTPADSPVFPVTPADSPVIPV-ASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAI 2007
Query: 781 RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLV 819
T DSPV + + + VT VPVTP S ++
Sbjct: 2008 PVTPTDSPVVPVTSADSPVIPVTADSPFVPVTPADSPVI 2046
Score = 34.7 bits (78), Expect = 0.39
Identities = 51/227 (22%), Positives = 89/227 (39%), Gaps = 31/227 (13%)
Query: 669 IYSSPIAG-VIPVTSSE-----LTAVNFPSFHVTPLK---LMVSPTSVAAVPVGNS---- 715
++ +P G V+PVT ++ + + + P VTP + V+P + VPV ++
Sbjct: 209 VHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVPVISADSPF 268
Query: 716 -PALASSHPVPIQNPSSAIV---------------NFTLQHLGLISPNVQLSASPGSGIV 759
P + + PV + + + +V + T+ V + IV
Sbjct: 269 VPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVTTADDPIV 328
Query: 760 PVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPV-PVTPKGSQL 818
PV+P +S ++ A + T DSP +G V VT A PV PVTP +
Sbjct: 329 PVTPA-DSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPV 387
Query: 819 VAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTED 865
V+ + +P P P + A+ + + V+T D
Sbjct: 388 VSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTAD 434
Score = 32.0 bits (71), Expect = 2.5
Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 17/164 (10%)
Query: 677 VIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPV-PIQNPSSAIVN 735
VIPVTS++ P +TP V P + A PV P + PV P+ + +V
Sbjct: 108 VIPVTSAD-----DPVVPITPADNPVVPVTSANGPV--IPVTPADSPVFPVASADGPVVP 160
Query: 736 FTLQHLGLISPNVQLSASPGSGIVPVSPRIESV-NVAPENAGTQQGRATNYDSPVPGQSQ 794
T SP ++ + S + PV+P + V P ++ T D PV +
Sbjct: 161 VTPAD----SPVFPVTPAD-SPLFPVTPADSPLFPVTPADSAAIP--VTPADGPVVHVTP 213
Query: 795 PNGQSVAVTGAQQP-VPVTPKGSQLVAESFFRTPGGPTKPTSSS 837
NG V VT A P V V S +V + P P P SS
Sbjct: 214 ANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSS 257
Score = 30.4 bits (67), Expect = 7.4
Identities = 41/176 (23%), Positives = 70/176 (39%), Gaps = 23/176 (13%)
Query: 695 VTPLKLMVSPTSVAAVPVGNS-----PALASSHPVPIQNPSSAIVNFTLQHLGLISP--- 746
V P+ ++V T + VPV + P + + V + + + +V G++ P
Sbjct: 26 VLPITVVVQ-TDGSVVPVTRAGSPFVPVIPADGLVVLDSSTDVLVVPVFPADGILVPDFA 84
Query: 747 -NVQLSASPGSGIV-PVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTG 804
N + +P +V PV+P +S + +A T D+PV + NG + VT
Sbjct: 85 DNPVVPVTPADDLVFPVTPA-DSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTP 143
Query: 805 AQQP-----------VPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSL 849
A P VPVTP S + + +P P P S A+ ++
Sbjct: 144 ADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPVTPADSAAI 199
>gi|4758226 E2F transcription factor 2 [Homo sapiens]
Length = 437
Score = 53.5 bits (127), Expect = 8e-07
Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 6/94 (6%)
Query: 110 QPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHM 169
+ +R + SLGLL KF+ + ++ L+ AE L+V++RRIYDI NVLE + +
Sbjct: 126 EKTRYDTSLGLLTKKFIYLLSESEDGVLD----LNWAAEVLDVQKRRIYDITNVLEGIQL 181
Query: 170 VSRLAKNRYTWHGRHNLNKTL--GTLKSIGEENK 201
+ + AKN W GR G + +G+E K
Sbjct: 182 IRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELK 215
Score = 45.4 bits (106), Expect = 2e-04
Identities = 74/319 (23%), Positives = 125/319 (39%), Gaps = 53/319 (16%)
Query: 260 SRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIA 319
+R D SL ++++KF+ L S ++ L AA++L D+ K RR+YDI
Sbjct: 128 TRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVL-------DVQK-------RRIYDIT 173
Query: 320 NVLSSLDLIKKVHVTEERGRKPAFKWTGPEI--SPNTSGSSPVIHFTPSDLEVRRSSKEN 377
NVL + LI+K K +W G + P G + +L + +
Sbjct: 174 NVLEGIQLIRK-------KAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQ 226
Query: 378 CAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKM 437
++ + + T + +L D R + + + KA P
Sbjct: 227 LIQS--CSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAP--------PQTR 276
Query: 438 AQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMEL-TAPSLIQPLGM 496
++ + L+ ++ ++V L +P +P + P+ + L +P QP
Sbjct: 277 LEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSS 336
Query: 497 V-PLIPSPLSSAVPLILP---QAPSGPSYAIYLQPTQAHQSV----------TPPQGLSP 542
P I P +S+VP P QAP PS L P +A S+ T Q LSP
Sbjct: 337 TDPSIMEPTASSVPAPAPTPQQAPPPPS----LVPLEATDSLLELPHPLLQQTEDQFLSP 392
Query: 543 TV-CTTHSSKATGSKDSTD 560
T+ C++ + S D D
Sbjct: 393 TLACSSPLISFSPSLDQDD 411
>gi|12669915 E2F transcription factor 4 [Homo sapiens]
Length = 413
Score = 53.1 bits (126), Expect = 1e-06
Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Query: 111 PSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMV 170
PSR EKSLGLL KF++ + ++ + D +A ++RRIYDI NVLE + ++
Sbjct: 15 PSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVR---QKRRIYDITNVLEGIGLI 71
Query: 171 SRLAKNRYTWHG 182
+ +KN W G
Sbjct: 72 EKKSKNSIQWKG 83
Score = 41.2 bits (95), Expect = 0.004
Identities = 76/342 (22%), Positives = 126/342 (36%), Gaps = 44/342 (12%)
Query: 260 SRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIA 319
SR +KSL +++ KFV L + ++ L++AA L RR+YDI
Sbjct: 16 SRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQK-------------RRIYDIT 62
Query: 320 NVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSG-SSPVIHFTPSDLEVRRSSKENC 378
NVL + LI E+ K + +W G NT + +I E+++ +E
Sbjct: 63 NVLEGIGLI-------EKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQREQELD 115
Query: 379 AKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMA 438
++ + N T L D + A + + + P P
Sbjct: 116 QHKVWVQQSIRNVTEDVQNSCLAYVTHEDICRC-FAGDTLLAIRAPSGTSLEVPIPE--- 171
Query: 439 QLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVA-PLDPPVNAEMELTAPSLIQPLGMV 497
L K Q+ +S +V + + PVA P+ PP + +A S PL
Sbjct: 172 GLNGQKKYQIHLKSVSGPIEVLLVNKEAWSSPPVAVPVPPPEDLLQSPSAVSTPPPLPKP 231
Query: 498 PLIPSPLSSA--VPLILPQAPSGPSYAIYLQPTQAHQSVTPPQG-------------LSP 542
L S +S P + P A G + + A +V+ G L P
Sbjct: 232 ALAQSQEASRPNSPQLTPTAVPGSAEVQGMAGPAAEITVSGGPGTDSKDSGELSSLPLGP 291
Query: 543 TVCTT---HSSKATGSKDSTDATTEKAANDTSKASASTRPGS 581
T T SS S S+ +++ ++N S +S+ P +
Sbjct: 292 TTLDTRPLQSSALLDSSSSSSSSSSSSSNSNSSSSSGPNPST 333
>gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]
Length = 345
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 12/138 (8%)
Query: 112 SRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVS 171
SR EKSLGLL KF++ + ++ D +A ++RRIYDI NVLE + ++
Sbjct: 49 SRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVR---QKRRIYDITNVLEGIDLIE 105
Query: 172 RLAKNRYTWHG---RHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKS--YSI 226
+ +KN W G N + + L+ + E + E +K++E +Q+ +++ ++
Sbjct: 106 KKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLE----LKERELDQQKLWLQQSIKNV 161
Query: 227 EDHIIKSNTGPNGHPDMC 244
D I + H D+C
Sbjct: 162 MDDSINNRFSYVTHEDIC 179
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 20/115 (17%)
Query: 255 AASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRR 314
A +SR +KSL +++ KFV L + ++ L+ AA L RR
Sbjct: 44 AGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQK-------------RR 90
Query: 315 LYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLE 369
+YDI NVL +DLI E+ K + +W G NT + + +++E
Sbjct: 91 IYDITNVLEGIDLI-------EKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIE 138
>gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]
Length = 346
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 12/138 (8%)
Query: 112 SRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVS 171
SR EKSLGLL KF++ + ++ D +A ++RRIYDI NVLE + ++
Sbjct: 49 SRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVR---QKRRIYDITNVLEGIDLIE 105
Query: 172 RLAKNRYTWHG---RHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKS--YSI 226
+ +KN W G N + + L+ + E + E +K++E +Q+ +++ ++
Sbjct: 106 KKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLE----LKERELDQQKLWLQQSIKNV 161
Query: 227 EDHIIKSNTGPNGHPDMC 244
D I + H D+C
Sbjct: 162 MDDSINNRFSYVTHEDIC 179
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 20/115 (17%)
Query: 255 AASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRR 314
A +SR +KSL +++ KFV L + ++ L+ AA L RR
Sbjct: 44 AGGGSSRHEKSLGLLTTKFVSLLQEAKDGVLDLKAAADTLAVRQK-------------RR 90
Query: 315 LYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLE 369
+YDI NVL +DLI E+ K + +W G NT + + +++E
Sbjct: 91 IYDITNVLEGIDLI-------EKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIE 138
>gi|45387951 transmembrane protein 108 [Homo sapiens]
Length = 575
Score = 51.6 bits (122), Expect = 3e-06
Identities = 97/405 (23%), Positives = 143/405 (35%), Gaps = 69/405 (17%)
Query: 491 IQPLGMVP--LIPSPLSS----AVPLILPQAPSGPSYAI--YLQPTQAHQSVTPPQGLSP 542
+ P G P ++ +P SS +V ++ P PS A PT + P +S
Sbjct: 40 VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTIST 99
Query: 543 TVCT-----THSSKATGSKDSTDATTEKAANDTSKASAS-----TRPGSLLPAPERQGAK 592
T + SS +TG + ATT + A+ T+P P +
Sbjct: 100 IAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPR 159
Query: 593 SRTREPAGERGSKRASMLEDS-------GSKKKFKEDLKGLENVSATLFPSGYLIPLTQC 645
+ TR P GS R S G + KE +G N S+T P G PL +
Sbjct: 160 TTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRG-RNPSST--PLGQKRPLGKI 216
Query: 646 SSLGAESILSGKE-NSSALSPNHRIY---SSPIAGVIPVTSSELTAVNFPSFHVTPLKLM 701
+ + E S L+P ++ SSP + T+ P
Sbjct: 217 FQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATT-------------VPSNTS 263
Query: 702 VSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPV 761
+PT+ + P + P L + Q S S A+ SG PV
Sbjct: 264 WAPTTTSLGPAKDKPGLRRA----AQGGGSTFT----------SQGGTPDATAASG-APV 308
Query: 762 SPRIESVNVAPENAGTQQGRATNYDS---PVPGQSQPNGQSVAV-TGAQQPVPVT----- 812
SP+ V + G Q ++ DS PG S+P S V T A P P
Sbjct: 309 SPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSV 368
Query: 813 PKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQR 857
SQ + + TP PT P+ S GA + ++ TL + R
Sbjct: 369 SAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDR 413
>gi|210147493 transmembrane protein 108 [Homo sapiens]
Length = 575
Score = 51.6 bits (122), Expect = 3e-06
Identities = 97/405 (23%), Positives = 143/405 (35%), Gaps = 69/405 (17%)
Query: 491 IQPLGMVP--LIPSPLSS----AVPLILPQAPSGPSYAI--YLQPTQAHQSVTPPQGLSP 542
+ P G P ++ +P SS +V ++ P PS A PT + P +S
Sbjct: 40 VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTIST 99
Query: 543 TVCT-----THSSKATGSKDSTDATTEKAANDTSKASAS-----TRPGSLLPAPERQGAK 592
T + SS +TG + ATT + A+ T+P P +
Sbjct: 100 IAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPR 159
Query: 593 SRTREPAGERGSKRASMLEDS-------GSKKKFKEDLKGLENVSATLFPSGYLIPLTQC 645
+ TR P GS R S G + KE +G N S+T P G PL +
Sbjct: 160 TTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRG-RNPSST--PLGQKRPLGKI 216
Query: 646 SSLGAESILSGKE-NSSALSPNHRIY---SSPIAGVIPVTSSELTAVNFPSFHVTPLKLM 701
+ + E S L+P ++ SSP + T+ P
Sbjct: 217 FQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATT-------------VPSNTS 263
Query: 702 VSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPV 761
+PT+ + P + P L + Q S S A+ SG PV
Sbjct: 264 WAPTTTSLGPAKDKPGLRRA----AQGGGSTFT----------SQGGTPDATAASG-APV 308
Query: 762 SPRIESVNVAPENAGTQQGRATNYDS---PVPGQSQPNGQSVAV-TGAQQPVPVT----- 812
SP+ V + G Q ++ DS PG S+P S V T A P P
Sbjct: 309 SPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSV 368
Query: 813 PKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQR 857
SQ + + TP PT P+ S GA + ++ TL + R
Sbjct: 369 SAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDR 413
>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
Length = 931
Score = 51.2 bits (121), Expect = 4e-06
Identities = 91/364 (25%), Positives = 139/364 (38%), Gaps = 44/364 (12%)
Query: 354 TSGSSPVIHFTPSDLEVRRSSKENCAKN----LFSTRGKPNFTRHPSLIKLVKSIESDRR 409
++GS+P + TPS+ + + EN T T S ++++ E R
Sbjct: 446 STGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRA 505
Query: 410 KINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSG-- 467
S SP + E K Q+ A+ +M ++Q R K++++ +
Sbjct: 506 --GSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQ 563
Query: 468 PCKPVAPLDPPVNAEMELTAPSLIQ-PLGMV-PLIPSPLSSAVPLILP--QAPSGPSYAI 523
P APL PV E ++ L Q PLG P PS + A I P AP PS +
Sbjct: 564 PAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVV 623
Query: 524 YLQ-------PTQAHQSVTPPQGLS-------PTVCTTHSSKATGSKDSTDATTEKA--- 566
+ P A Q + PQG S PT+ T +TG+ T + A
Sbjct: 624 KQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITD----STGTHLVLTVTNKNADSP 679
Query: 567 -ANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKG 625
+ S S++PGS PAP Q +P + E G ++ + K
Sbjct: 680 GLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKK-EPPGYEEAMSQQPKQ 738
Query: 626 LENVSATLFPSGYLIPLTQCSSLGAE----SILSGKENSSALSPNHRIYSSPIAGVIPVT 681
EN S++ L Q + A+ L GKE S + + SP+A P
Sbjct: 739 QENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKT----VCGSPLAAQ-PSP 793
Query: 682 SSEL 685
S+EL
Sbjct: 794 SAEL 797
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 49.7 bits (117), Expect = 1e-05
Identities = 105/477 (22%), Positives = 180/477 (37%), Gaps = 65/477 (13%)
Query: 395 PSLIK-LVKSIESDRRKIN-SAP-------SSPIKTNKAESSQNSAPFP-SKMAQLAAIC 444
P+L++ L+K + S +++ SAP SSP+ + S+P P + LA+
Sbjct: 1368 PTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPV 1427
Query: 445 KMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPL 504
+ S S + + + + P APL P++A + ++A P + + +
Sbjct: 1428 SSTVSVPLSSS---LPISVPTTLPAPASAPLTIPISAPLTVSASG--------PALLTSV 1476
Query: 505 SSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTE 564
+ + ++P AP PS L P+ A S + T + SS+ G T+
Sbjct: 1477 TPPLAPVVPAAPGPPS----LAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSS 1532
Query: 565 KAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLK 624
S + + P L+PA PA + S A S + +
Sbjct: 1533 HVPGLNSTVAPACSP-VLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMA 1591
Query: 625 GLENVSATLFPSGYLIPL-TQCSSLGAESILSGKEN-----SSALSPNHRIYS-SPIAGV 677
+ P+ L PL S GA +L+ + + + +P + S SP+
Sbjct: 1592 APQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAP 1651
Query: 678 IPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPV------GNSPALASS-------HPV 724
PV + T P+ +PL S ++A P G+SP+ S P
Sbjct: 1652 TPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711
Query: 725 PIQ----NPSSAIVNFTLQHLGL-----ISPNVQLSASPGSGIVPVSP----RIESVNVA 771
P Q P+S++V Q L L + P LS +P + P SP ++ +A
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771
Query: 772 PEN------AGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAES 822
P + A T +PVP Q++A+ A P + S +V+ S
Sbjct: 1772 PASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSAS 1828
Score = 41.2 bits (95), Expect = 0.004
Identities = 75/308 (24%), Positives = 113/308 (36%), Gaps = 30/308 (9%)
Query: 490 LIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLS-PTVCTTH 548
L+ G LI P + V LI AP+ + + P+ + P GLS P
Sbjct: 1241 LVSAGGQHHLISQP--AHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQV 1298
Query: 549 SSKATGSKDSTDATTEKAAND-----TSKASASTRPGSLLPAP-ERQGAKSRTREPAGER 602
+ +A D A A P S LPA + + R P
Sbjct: 1299 PPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTL 1358
Query: 603 GSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSA 662
G+ RA M + + K VSA+ + PLT S L S L G +S
Sbjct: 1359 GTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAA---PLTISSPLHVPSSLPGPASSPM 1415
Query: 663 LSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKL-MVSPTSVAAVPVGNSPALASS 721
PN +SP++ + V S ++ P+ P + P S + PAL +S
Sbjct: 1416 PIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTS 1475
Query: 722 HPVPIQ------------NPSSAIVNFTLQHLGL-ISPNVQLSASPGSGIV--PVSPRIE 766
P+ PS A + + LGL +P++ S +PG ++ P S +
Sbjct: 1476 VTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP 1535
Query: 767 SVN--VAP 772
+N VAP
Sbjct: 1536 GLNSTVAP 1543
Score = 32.0 bits (71), Expect = 2.5
Identities = 62/267 (23%), Positives = 97/267 (36%), Gaps = 30/267 (11%)
Query: 476 DPPVNAEMELTAPSLIQPL---GMVPLIPSPLSSAVPLILP---QAPSGPSYAIYLQPTQ 529
DP E + A +++P G PL P P+ PL+ P + P A L
Sbjct: 2893 DPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPG 2952
Query: 530 AHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPA--PE 587
S S T H S T T AN + + ST P P+
Sbjct: 2953 TISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPK 3012
Query: 588 RQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSS 647
+ ++ P +R S S+LE G ++ + +G E+ ++ G PLT+ +
Sbjct: 3013 NPPSPRPSQLPVLDRDS--TSVLESCGLGRRRQPQGQG-ESEGSSSDEDGSR-PLTRLAR 3068
Query: 648 LGAESI-LSGKENSSAL--------------SPNHRIYSSPIAGVIPVTSSELTAVNFPS 692
L E+ + G+++ ++ P + P+ + P S P
Sbjct: 3069 LRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLR---PG 3125
Query: 693 FHVTPLKLMVSPTSVAAVPVGNSPALA 719
V PL+ P A PVG SP LA
Sbjct: 3126 SLVPPLETEKLPRKRAGAPVGGSPGLA 3152
Score = 31.2 bits (69), Expect = 4.3
Identities = 74/357 (20%), Positives = 122/357 (34%), Gaps = 39/357 (10%)
Query: 465 RSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIY 524
R P + P P +AP+ I L +P P+S+ VP+ P I
Sbjct: 2428 RCSPARERVPRPAPRPRPTPASAPAAIPAL-----VPVPVSAPVPISAPN-------PIT 2475
Query: 525 LQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLP 584
+ P S PP + P C++ + + A T A +S LL
Sbjct: 2476 ILPVHILPSPPPPSQIPP--CSSPACTPPPACTPPPAHTPPPAQTCLVTPSSP---LLLG 2530
Query: 585 APERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQ 644
P + S T P G R + + + E S +L P L+P+
Sbjct: 2531 PPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPV-- 2588
Query: 645 CSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSP 704
A IL E + +L+P S+P S L A + P+
Sbjct: 2589 -----AVEILPVSEKNLSLTP-----SAP--------SLTLEAGSIPNGQEQEAPDSAEG 2630
Query: 705 TSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQH-LGLISPNVQLSASPGSGIVPVSP 763
T++ +P G L S ++ P SA + LQ L + +L+ + P P
Sbjct: 2631 TTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKP 2690
Query: 764 R-IESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLV 819
+ + + VA + + + SP + V + G P P G +++
Sbjct: 2691 QELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVL 2747
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 47.4 bits (111), Expect = 6e-05
Identities = 102/455 (22%), Positives = 158/455 (34%), Gaps = 82/455 (18%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
SAP++P + + P P+ + A + +++S + A + P KP
Sbjct: 254 SAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 473 --APLDPPVNAEMELT-------APSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
P +P E T AP+ +P P P+P + P P P P+
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTT 368
Query: 524 YLQP---TQAHQSVTPPQGLSPTVC------------TTHSSKATGSKDSTDATTEKAAN 568
+P T S T P+ +PT TT S T K+ + TT++ A
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 569 DTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLEN 628
T K A T P P ++ A + +EPA K A KE
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--------KEPAPTTPK 480
Query: 629 VSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAV 688
+A P L P T E + +P ++P + P T E T
Sbjct: 481 ETAPTTPK-KLTPTT-------------PEKLAPTTPEKPAPTTP-EELAPTTPEEPTP- 524
Query: 689 NFPSFHVTPLKLMVSPTSVAAVPVGNSPA-LASSHPVPI--QNPSSAIVNFTLQHLGLIS 745
TP + + AA PA P P + P+ T +
Sbjct: 525 ------TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-------A 571
Query: 746 PNVQLSASPGS--GIVPVSPRIES-VNVAPENAGTQQGRATNYDSPVP----GQSQPNGQ 798
P +P + P +P+ + +AP T++ +T D P P G + +
Sbjct: 572 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 799 SVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKP 833
A T ++P P TPKG+ A + + P PT P
Sbjct: 630 EPAPTTPKEPAPTTPKGT---APTTLKEP-APTTP 660
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/256 (21%), Positives = 89/256 (34%), Gaps = 25/256 (9%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P P+ + + P T+ P+ +
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPT 296
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKVQL 463
+ + + P P T E + + P P+ + A K + + + K
Sbjct: 297 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK-----EPAPTTPKEPAPT 351
Query: 464 ARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
A P P P +P E + +P P P+P ++ S P+
Sbjct: 352 APKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---------SAPTTTK 401
Query: 524 YLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLL 583
PT + T P+ SPT TT T K+ T +K A T K A T P
Sbjct: 402 EPAPTTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459
Query: 584 PAPERQGAKSRTREPA 599
P ++ A + +EPA
Sbjct: 460 PTTTKKPAPTTPKEPA 475
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 20/262 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFT--RHPSLIKLVKS 403
T E +P T+ S+P P+ ++ + + +T +P T + P+ +
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341
Query: 404 IESDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKV 461
+ + +AP P T E + + P P+ + + + +++S
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 401
Query: 462 QLA----RSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPS 517
+ A +S P P P P E T P +P P P+P + P P P
Sbjct: 402 EPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPK--EPAPTTPKKPAPTTPKEPA--PTTPK 456
Query: 518 GPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAST 577
P+ +P T P+ +PT T + T K T T EK A T + A T
Sbjct: 457 EPAPTTTKKPAP-----TTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 509
Query: 578 RPGSLLPAPERQGAKSRTREPA 599
P L P + + EPA
Sbjct: 510 TPEELAPTTPEEPTPTTPEEPA 531
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/263 (20%), Positives = 87/263 (33%), Gaps = 20/263 (7%)
Query: 348 PEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESD 407
P + PN+ S + V K ST GK T K +SIE
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-STDGKEKTTS----AKETQSIEKT 182
Query: 408 RRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSG 467
K + AP+S + ++ + P+ E S+ ++ + +S
Sbjct: 183 SAK-DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-KSA 240
Query: 468 PCKPVAPLDPPVNAEMELTAP------SLIQPLGMVPLIPSPLSSAVPL-----ILPQAP 516
P P P P + T P + +P P P+P ++ P P P
Sbjct: 241 PTTPKEPA--PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298
Query: 517 SGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAS 576
P+ +P P TT A +K+ T ++ A K A
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + T+EP+
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPS 381
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/274 (20%), Positives = 89/274 (32%), Gaps = 20/274 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P PS + + + +T KP T
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQK----VKV 461
+ AP++P + + + P K+ E+ + + +K
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTTPE 512
Query: 462 QLARSGPCKPV-------APLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPL-ILP 513
+LA + P +P AP P A P+ P P P + P P
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572
Query: 514 QAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKA 573
P G + +P P+ L+PT TT +T T + A T K
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPT--TTKEPTSTTCDKPAPTTPKGTAPTTPKE 630
Query: 574 SASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
A T P P + A + +EPA K A
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 664
Score = 38.9 bits (89), Expect = 0.021
Identities = 46/203 (22%), Positives = 72/203 (35%), Gaps = 17/203 (8%)
Query: 414 APSSPIK---TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCK 470
AP++P + T E + + P+ AA E + ++ P
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566
Query: 471 P--VAPLDPPVNAEMELTAPSLIQPLGMVP--LIPS----PLSSAVPLILPQAPSGPSYA 522
P AP P A L P+ P P L P+ P S+ P P G +
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 626
Query: 523 IYLQP---TQAHQSVTPPQGLSPTVC---TTHSSKATGSKDSTDATTEKAANDTSKASAS 576
+P T + T P+G +PT + K K+ TT+ + TS A
Sbjct: 627 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + ++PA
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPA 709
Score = 37.7 bits (86), Expect = 0.046
Identities = 45/224 (20%), Positives = 73/224 (32%), Gaps = 20/224 (8%)
Query: 384 STRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAI 443
+T+ P T+ P+ + + + P P T E + + P+
Sbjct: 392 TTKSAPTTTKEPA--------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443
Query: 444 CKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSP 503
E + ++ + P P P P E T P + P L P+
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTT 502
Query: 504 LSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATT 563
P+ P+ P+ L PT + TP P T ++ K+ T
Sbjct: 503 ---------PEKPA-PTTPEELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 564 EKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
++ A T K A T P P + A + +EPA K A
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Score = 37.0 bits (84), Expect = 0.079
Identities = 31/136 (22%), Positives = 46/136 (33%), Gaps = 7/136 (5%)
Query: 470 KPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLI-LPQAPSGPSYAIYLQPT 528
K +AP P+ P G P P + P P P G + +P
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 656
Query: 529 QAHQSVTPPQGLSPTVC------TTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSL 582
P+ L+PT T+ T K++ T ++ A T K A T P +
Sbjct: 657 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 716
Query: 583 LPAPERQGAKSRTREP 598
P + T+EP
Sbjct: 717 PPTTSEVSTPTTTKEP 732
Score = 31.6 bits (70), Expect = 3.3
Identities = 49/211 (23%), Positives = 78/211 (36%), Gaps = 27/211 (12%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
+AP++P T + + P K A E S+ + + P P
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 473 --APLDP--PVNAEMELTAPSLI-QPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQP 527
AP P P + TAP+ + +P P P+P A P GP+ +P
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKGPTSTTSDKP 684
Query: 528 ---TQAHQSVTPPQGLSPTV------CTTHSSKATGSKDSTDATTEKAA-------NDTS 571
T + T P+ +PT T + T S+ ST TT++ T
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 744
Query: 572 KASASTRPGSLLPAPERQGAKSRTREPAGER 602
+ SA P +L +P+ G + T+ PA +
Sbjct: 745 ELSAEPTPKALENSPKEPGVPT-TKTPAATK 774
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 47.4 bits (111), Expect = 6e-05
Identities = 102/455 (22%), Positives = 158/455 (34%), Gaps = 82/455 (18%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
SAP++P + + P P+ + A + +++S + A + P KP
Sbjct: 295 SAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 473 --APLDPPVNAEMELT-------APSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
P +P E T AP+ +P P P+P + P P P P+
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTT 409
Query: 524 YLQP---TQAHQSVTPPQGLSPTVC------------TTHSSKATGSKDSTDATTEKAAN 568
+P T S T P+ +PT TT S T K+ + TT++ A
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 569 DTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLEN 628
T K A T P P ++ A + +EPA K A KE
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--------KEPAPTTPK 521
Query: 629 VSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAV 688
+A P L P T E + +P ++P + P T E T
Sbjct: 522 ETAPTTPK-KLTPTT-------------PEKLAPTTPEKPAPTTP-EELAPTTPEEPTP- 565
Query: 689 NFPSFHVTPLKLMVSPTSVAAVPVGNSPA-LASSHPVPI--QNPSSAIVNFTLQHLGLIS 745
TP + + AA PA P P + P+ T +
Sbjct: 566 ------TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-------A 612
Query: 746 PNVQLSASPGS--GIVPVSPRIES-VNVAPENAGTQQGRATNYDSPVP----GQSQPNGQ 798
P +P + P +P+ + +AP T++ +T D P P G + +
Sbjct: 613 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 799 SVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKP 833
A T ++P P TPKG+ A + + P PT P
Sbjct: 671 EPAPTTPKEPAPTTPKGT---APTTLKEP-APTTP 701
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/256 (21%), Positives = 89/256 (34%), Gaps = 25/256 (9%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P P+ + + P T+ P+ +
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPT 337
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKVQL 463
+ + + P P T E + + P P+ + A K + + + K
Sbjct: 338 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK-----EPAPTTPKEPAPT 392
Query: 464 ARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
A P P P +P E + +P P P+P ++ S P+
Sbjct: 393 APKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---------SAPTTTK 442
Query: 524 YLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLL 583
PT + T P+ SPT TT T K+ T +K A T K A T P
Sbjct: 443 EPAPTTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500
Query: 584 PAPERQGAKSRTREPA 599
P ++ A + +EPA
Sbjct: 501 PTTTKKPAPTTPKEPA 516
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 20/262 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFT--RHPSLIKLVKS 403
T E +P T+ S+P P+ ++ + + +T +P T + P+ +
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382
Query: 404 IESDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKV 461
+ + +AP P T E + + P P+ + + + +++S
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 442
Query: 462 QLA----RSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPS 517
+ A +S P P P P E T P +P P P+P + P P P
Sbjct: 443 EPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPK--EPAPTTPKKPAPTTPKEPA--PTTPK 497
Query: 518 GPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAST 577
P+ +P T P+ +PT T + T K T T EK A T + A T
Sbjct: 498 EPAPTTTKKPAP-----TTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 550
Query: 578 RPGSLLPAPERQGAKSRTREPA 599
P L P + + EPA
Sbjct: 551 TPEELAPTTPEEPTPTTPEEPA 572
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/263 (20%), Positives = 87/263 (33%), Gaps = 20/263 (7%)
Query: 348 PEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESD 407
P + PN+ S + V K ST GK T K +SIE
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-STDGKEKTTS----AKETQSIEKT 223
Query: 408 RRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSG 467
K + AP+S + ++ + P+ E S+ ++ + +S
Sbjct: 224 SAK-DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-KSA 281
Query: 468 PCKPVAPLDPPVNAEMELTAP------SLIQPLGMVPLIPSPLSSAVPL-----ILPQAP 516
P P P P + T P + +P P P+P ++ P P P
Sbjct: 282 PTTPKEPA--PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339
Query: 517 SGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAS 576
P+ +P P TT A +K+ T ++ A K A
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + T+EP+
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPS 422
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/274 (20%), Positives = 89/274 (32%), Gaps = 20/274 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P PS + + + +T KP T
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQK----VKV 461
+ AP++P + + + P K+ E+ + + +K
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTTPE 553
Query: 462 QLARSGPCKPV-------APLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPL-ILP 513
+LA + P +P AP P A P+ P P P + P P
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613
Query: 514 QAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKA 573
P G + +P P+ L+PT TT +T T + A T K
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPT--TTKEPTSTTCDKPAPTTPKGTAPTTPKE 671
Query: 574 SASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
A T P P + A + +EPA K A
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 705
Score = 38.9 bits (89), Expect = 0.021
Identities = 46/203 (22%), Positives = 72/203 (35%), Gaps = 17/203 (8%)
Query: 414 APSSPIK---TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCK 470
AP++P + T E + + P+ AA E + ++ P
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607
Query: 471 P--VAPLDPPVNAEMELTAPSLIQPLGMVP--LIPS----PLSSAVPLILPQAPSGPSYA 522
P AP P A L P+ P P L P+ P S+ P P G +
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667
Query: 523 IYLQP---TQAHQSVTPPQGLSPTVC---TTHSSKATGSKDSTDATTEKAANDTSKASAS 576
+P T + T P+G +PT + K K+ TT+ + TS A
Sbjct: 668 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + ++PA
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPA 750
Score = 37.7 bits (86), Expect = 0.046
Identities = 45/224 (20%), Positives = 73/224 (32%), Gaps = 20/224 (8%)
Query: 384 STRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAI 443
+T+ P T+ P+ + + + P P T E + + P+
Sbjct: 433 TTKSAPTTTKEPA--------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484
Query: 444 CKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSP 503
E + ++ + P P P P E T P + P L P+
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTT 543
Query: 504 LSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATT 563
P+ P+ P+ L PT + TP P T ++ K+ T
Sbjct: 544 ---------PEKPA-PTTPEELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 564 EKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
++ A T K A T P P + A + +EPA K A
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Score = 37.0 bits (84), Expect = 0.079
Identities = 31/136 (22%), Positives = 46/136 (33%), Gaps = 7/136 (5%)
Query: 470 KPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLI-LPQAPSGPSYAIYLQPT 528
K +AP P+ P G P P + P P P G + +P
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 697
Query: 529 QAHQSVTPPQGLSPTVC------TTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSL 582
P+ L+PT T+ T K++ T ++ A T K A T P +
Sbjct: 698 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 757
Query: 583 LPAPERQGAKSRTREP 598
P + T+EP
Sbjct: 758 PPTTSEVSTPTTTKEP 773
Score = 31.6 bits (70), Expect = 3.3
Identities = 49/211 (23%), Positives = 78/211 (36%), Gaps = 27/211 (12%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
+AP++P T + + P K A E S+ + + P P
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 473 --APLDP--PVNAEMELTAPSLI-QPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQP 527
AP P P + TAP+ + +P P P+P A P GP+ +P
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKGPTSTTSDKP 725
Query: 528 ---TQAHQSVTPPQGLSPTV------CTTHSSKATGSKDSTDATTEKAA-------NDTS 571
T + T P+ +PT T + T S+ ST TT++ T
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 785
Query: 572 KASASTRPGSLLPAPERQGAKSRTREPAGER 602
+ SA P +L +P+ G + T+ PA +
Sbjct: 786 ELSAEPTPKALENSPKEPGVPT-TKTPAATK 815
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 47.4 bits (111), Expect = 6e-05
Identities = 102/455 (22%), Positives = 158/455 (34%), Gaps = 82/455 (18%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
SAP++P + + P P+ + A + +++S + A + P KP
Sbjct: 347 SAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 473 --APLDPPVNAEMELT-------APSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
P +P E T AP+ +P P P+P + P P P P+
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTT 461
Query: 524 YLQP---TQAHQSVTPPQGLSPTVC------------TTHSSKATGSKDSTDATTEKAAN 568
+P T S T P+ +PT TT S T K+ + TT++ A
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 569 DTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLEN 628
T K A T P P ++ A + +EPA K A KE
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--------KEPAPTTPK 573
Query: 629 VSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAV 688
+A P L P T E + +P ++P + P T E T
Sbjct: 574 ETAPTTPK-KLTPTT-------------PEKLAPTTPEKPAPTTP-EELAPTTPEEPTP- 617
Query: 689 NFPSFHVTPLKLMVSPTSVAAVPVGNSPA-LASSHPVPI--QNPSSAIVNFTLQHLGLIS 745
TP + + AA PA P P + P+ T +
Sbjct: 618 ------TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-------A 664
Query: 746 PNVQLSASPGS--GIVPVSPRIES-VNVAPENAGTQQGRATNYDSPVP----GQSQPNGQ 798
P +P + P +P+ + +AP T++ +T D P P G + +
Sbjct: 665 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAPTTPK 722
Query: 799 SVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKP 833
A T ++P P TPKG+ A + + P PT P
Sbjct: 723 EPAPTTPKEPAPTTPKGT---APTTLKEP-APTTP 753
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/256 (21%), Positives = 89/256 (34%), Gaps = 25/256 (9%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P P+ + + P T+ P+ +
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPT 389
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKVQL 463
+ + + P P T E + + P P+ + A K + + + K
Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK-----EPAPTTPKEPAPT 444
Query: 464 ARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
A P P P +P E + +P P P+P ++ S P+
Sbjct: 445 APKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---------SAPTTTK 494
Query: 524 YLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLL 583
PT + T P+ SPT TT T K+ T +K A T K A T P
Sbjct: 495 EPAPTTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 584 PAPERQGAKSRTREPA 599
P ++ A + +EPA
Sbjct: 553 PTTTKKPAPTTPKEPA 568
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 20/262 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFT--RHPSLIKLVKS 403
T E +P T+ S+P P+ ++ + + +T +P T + P+ +
Sbjct: 375 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434
Query: 404 IESDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKV 461
+ + +AP P T E + + P P+ + + + +++S
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 494
Query: 462 QLA----RSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPS 517
+ A +S P P P P E T P +P P P+P + P P P
Sbjct: 495 EPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPK--EPAPTTPKKPAPTTPKEPA--PTTPK 549
Query: 518 GPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAST 577
P+ +P T P+ +PT T + T K T T EK A T + A T
Sbjct: 550 EPAPTTTKKPAP-----TTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 602
Query: 578 RPGSLLPAPERQGAKSRTREPA 599
P L P + + EPA
Sbjct: 603 TPEELAPTTPEEPTPTTPEEPA 624
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/263 (20%), Positives = 87/263 (33%), Gaps = 20/263 (7%)
Query: 348 PEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESD 407
P + PN+ S + V K ST GK T K +SIE
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-STDGKEKTTS----AKETQSIEKT 275
Query: 408 RRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSG 467
K + AP+S + ++ + P+ E S+ ++ + +S
Sbjct: 276 SAK-DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-KSA 333
Query: 468 PCKPVAPLDPPVNAEMELTAP------SLIQPLGMVPLIPSPLSSAVPL-----ILPQAP 516
P P P P + T P + +P P P+P ++ P P P
Sbjct: 334 PTTPKEPA--PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 517 SGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAS 576
P+ +P P TT A +K+ T ++ A K A
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + T+EP+
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPS 474
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/274 (20%), Positives = 89/274 (32%), Gaps = 20/274 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P PS + + + +T KP T
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQK----VKV 461
+ AP++P + + + P K+ E+ + + +K
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTTPE 605
Query: 462 QLARSGPCKPV-------APLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPL-ILP 513
+LA + P +P AP P A P+ P P P + P P
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665
Query: 514 QAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKA 573
P G + +P P+ L+PT TT +T T + A T K
Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPT--TTKEPTSTTCDKPAPTTPKGTAPTTPKE 723
Query: 574 SASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
A T P P + A + +EPA K A
Sbjct: 724 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 757
Score = 38.9 bits (89), Expect = 0.021
Identities = 46/203 (22%), Positives = 72/203 (35%), Gaps = 17/203 (8%)
Query: 414 APSSPIK---TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCK 470
AP++P + T E + + P+ AA E + ++ P
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659
Query: 471 P--VAPLDPPVNAEMELTAPSLIQPLGMVP--LIPS----PLSSAVPLILPQAPSGPSYA 522
P AP P A L P+ P P L P+ P S+ P P G +
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719
Query: 523 IYLQP---TQAHQSVTPPQGLSPTVC---TTHSSKATGSKDSTDATTEKAANDTSKASAS 576
+P T + T P+G +PT + K K+ TT+ + TS A
Sbjct: 720 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + ++PA
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPA 802
Score = 37.7 bits (86), Expect = 0.046
Identities = 45/224 (20%), Positives = 73/224 (32%), Gaps = 20/224 (8%)
Query: 384 STRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAI 443
+T+ P T+ P+ + + + P P T E + + P+
Sbjct: 485 TTKSAPTTTKEPA--------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536
Query: 444 CKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSP 503
E + ++ + P P P P E T P + P L P+
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTT 595
Query: 504 LSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATT 563
P+ P+ P+ L PT + TP P T ++ K+ T
Sbjct: 596 ---------PEKPA-PTTPEELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 564 EKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
++ A T K A T P P + A + +EPA K A
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 688
Score = 37.0 bits (84), Expect = 0.079
Identities = 31/136 (22%), Positives = 46/136 (33%), Gaps = 7/136 (5%)
Query: 470 KPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLI-LPQAPSGPSYAIYLQPT 528
K +AP P+ P G P P + P P P G + +P
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749
Query: 529 QAHQSVTPPQGLSPTVC------TTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSL 582
P+ L+PT T+ T K++ T ++ A T K A T P +
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809
Query: 583 LPAPERQGAKSRTREP 598
P + T+EP
Sbjct: 810 PPTTSEVSTPTTTKEP 825
Score = 31.6 bits (70), Expect = 3.3
Identities = 49/211 (23%), Positives = 78/211 (36%), Gaps = 27/211 (12%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
+AP++P T + + P K A E S+ + + P P
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 722
Query: 473 --APLDP--PVNAEMELTAPSLI-QPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQP 527
AP P P + TAP+ + +P P P+P A P GP+ +P
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKGPTSTTSDKP 777
Query: 528 ---TQAHQSVTPPQGLSPTV------CTTHSSKATGSKDSTDATTEKAA-------NDTS 571
T + T P+ +PT T + T S+ ST TT++ T
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 572 KASASTRPGSLLPAPERQGAKSRTREPAGER 602
+ SA P +L +P+ G + T+ PA +
Sbjct: 838 ELSAEPTPKALENSPKEPGVPT-TKTPAATK 867
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 47.4 bits (111), Expect = 6e-05
Identities = 102/455 (22%), Positives = 158/455 (34%), Gaps = 82/455 (18%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
SAP++P + + P P+ + A + +++S + A + P KP
Sbjct: 388 SAPTTP---KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 473 --APLDPPVNAEMELT-------APSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
P +P E T AP+ +P P P+P + P P P P+
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--PTTPKEPAPTT 502
Query: 524 YLQP---TQAHQSVTPPQGLSPTVC------------TTHSSKATGSKDSTDATTEKAAN 568
+P T S T P+ +PT TT S T K+ + TT++ A
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 569 DTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLEN 628
T K A T P P ++ A + +EPA K A KE
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP--------KEPAPTTPK 614
Query: 629 VSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAV 688
+A P L P T E + +P ++P + P T E T
Sbjct: 615 ETAPTTPK-KLTPTT-------------PEKLAPTTPEKPAPTTP-EELAPTTPEEPTP- 658
Query: 689 NFPSFHVTPLKLMVSPTSVAAVPVGNSPA-LASSHPVPI--QNPSSAIVNFTLQHLGLIS 745
TP + + AA PA P P + P+ T +
Sbjct: 659 ------TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-------A 705
Query: 746 PNVQLSASPGS--GIVPVSPRIES-VNVAPENAGTQQGRATNYDSPVP----GQSQPNGQ 798
P +P + P +P+ + +AP T++ +T D P P G + +
Sbjct: 706 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAPTTPK 763
Query: 799 SVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKP 833
A T ++P P TPKG+ A + + P PT P
Sbjct: 764 EPAPTTPKEPAPTTPKGT---APTTLKEP-APTTP 794
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/256 (21%), Positives = 89/256 (34%), Gaps = 25/256 (9%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P P+ + + P T+ P+ +
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTTKSAPT 430
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKVQL 463
+ + + P P T E + + P P+ + A K + + + K
Sbjct: 431 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK-----EPAPTTPKEPAPT 485
Query: 464 ARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAI 523
A P P P +P E + +P P P+P ++ S P+
Sbjct: 486 APKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK---------SAPTTTK 535
Query: 524 YLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLL 583
PT + T P+ SPT TT T K+ T +K A T K A T P
Sbjct: 536 EPAPTTTKSAPTTPKEPSPT--TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 584 PAPERQGAKSRTREPA 599
P ++ A + +EPA
Sbjct: 594 PTTTKKPAPTTPKEPA 609
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/262 (22%), Positives = 96/262 (36%), Gaps = 20/262 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFT--RHPSLIKLVKS 403
T E +P T+ S+P P+ ++ + + +T +P T + P+ +
Sbjct: 416 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475
Query: 404 IESDRRKINSAPSSPIKTNKAESSQNSA--PFPSKMAQLAAICKMQLEEQSSESRQKVKV 461
+ + +AP P T E + + P P+ + + + +++S
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 535
Query: 462 QLA----RSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPS 517
+ A +S P P P P E T P +P P P+P + P P P
Sbjct: 536 EPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPK--EPAPTTPKKPAPTTPKEPA--PTTPK 590
Query: 518 GPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAST 577
P+ +P T P+ +PT T + T K T T EK A T + A T
Sbjct: 591 EPAPTTTKKPAP-----TTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 643
Query: 578 RPGSLLPAPERQGAKSRTREPA 599
P L P + + EPA
Sbjct: 644 TPEELAPTTPEEPTPTTPEEPA 665
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/263 (20%), Positives = 87/263 (33%), Gaps = 20/263 (7%)
Query: 348 PEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESD 407
P + PN+ S + V K ST GK T K +SIE
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT-STDGKEKTTS----AKETQSIEKT 316
Query: 408 RRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSG 467
K + AP+S + ++ + P+ E S+ ++ + +S
Sbjct: 317 SAK-DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-KSA 374
Query: 468 PCKPVAPLDPPVNAEMELTAP------SLIQPLGMVPLIPSPLSSAVPL-----ILPQAP 516
P P P P + T P + +P P P+P ++ P P P
Sbjct: 375 PTTPKEPA--PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 517 SGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAS 576
P+ +P P TT A +K+ T ++ A K A
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + T+EP+
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPS 515
Score = 38.9 bits (89), Expect = 0.021
Identities = 57/274 (20%), Positives = 89/274 (32%), Gaps = 20/274 (7%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T E +P T+ S+P PS + + + +T KP T
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQK----VKV 461
+ AP++P + + + P K+ E+ + + +K
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP------EKLAPTTPEKPAPTTPE 646
Query: 462 QLARSGPCKPV-------APLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPL-ILP 513
+LA + P +P AP P A P+ P P P + P P
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706
Query: 514 QAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKA 573
P G + +P P+ L+PT TT +T T + A T K
Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPT--TTKEPTSTTCDKPAPTTPKGTAPTTPKE 764
Query: 574 SASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
A T P P + A + +EPA K A
Sbjct: 765 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 798
Score = 38.9 bits (89), Expect = 0.021
Identities = 46/203 (22%), Positives = 72/203 (35%), Gaps = 17/203 (8%)
Query: 414 APSSPIK---TNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCK 470
AP++P + T E + + P+ AA E + ++ P
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700
Query: 471 P--VAPLDPPVNAEMELTAPSLIQPLGMVP--LIPS----PLSSAVPLILPQAPSGPSYA 522
P AP P A L P+ P P L P+ P S+ P P G +
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760
Query: 523 IYLQP---TQAHQSVTPPQGLSPTVC---TTHSSKATGSKDSTDATTEKAANDTSKASAS 576
+P T + T P+G +PT + K K+ TT+ + TS A
Sbjct: 761 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820
Query: 577 TRPGSLLPAPERQGAKSRTREPA 599
T P P ++ A + ++PA
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPA 843
Score = 37.7 bits (86), Expect = 0.046
Identities = 45/224 (20%), Positives = 73/224 (32%), Gaps = 20/224 (8%)
Query: 384 STRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAI 443
+T+ P T+ P+ + + + P P T E + + P+
Sbjct: 526 TTKSAPTTTKEPA--------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577
Query: 444 CKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSP 503
E + ++ + P P P P E T P + P L P+
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTT 636
Query: 504 LSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATT 563
P+ P+ P+ L PT + TP P T ++ K+ T
Sbjct: 637 ---------PEKPA-PTTPEELAPTTPEEP-TPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Query: 564 EKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRA 607
++ A T K A T P P + A + +EPA K A
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 729
Score = 37.0 bits (84), Expect = 0.079
Identities = 31/136 (22%), Positives = 46/136 (33%), Gaps = 7/136 (5%)
Query: 470 KPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLI-LPQAPSGPSYAIYLQPT 528
K +AP P+ P G P P + P P P G + +P
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790
Query: 529 QAHQSVTPPQGLSPTVC------TTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSL 582
P+ L+PT T+ T K++ T ++ A T K A T P +
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850
Query: 583 LPAPERQGAKSRTREP 598
P + T+EP
Sbjct: 851 PPTTSEVSTPTTTKEP 866
Score = 31.6 bits (70), Expect = 3.3
Identities = 49/211 (23%), Positives = 78/211 (36%), Gaps = 27/211 (12%)
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
+AP++P T + + P K A E S+ + + P P
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 763
Query: 473 --APLDP--PVNAEMELTAPSLI-QPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQP 527
AP P P + TAP+ + +P P P+P A P GP+ +P
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKGPTSTTSDKP 818
Query: 528 ---TQAHQSVTPPQGLSPTV------CTTHSSKATGSKDSTDATTEKAA-------NDTS 571
T + T P+ +PT T + T S+ ST TT++ T
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 572 KASASTRPGSLLPAPERQGAKSRTREPAGER 602
+ SA P +L +P+ G + T+ PA +
Sbjct: 879 ELSAEPTPKALENSPKEPGVPT-TKTPAATK 908
>gi|109637795 E2F transcription factor 6 [Homo sapiens]
Length = 281
Score = 47.4 bits (111), Expect = 6e-05
Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 9/106 (8%)
Query: 108 KSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESL 167
K + R + SL L KF+ + P ++ L++VA +L V +RR+YDI NVL+ +
Sbjct: 58 KVKRPRFDVSLVYLTRKFMDLVRSAPGGILD----LNKVATKLGVRKRRVYDITNVLDGI 113
Query: 168 HMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKE 213
+V + +KN W G L ++ ++ K E++ + E
Sbjct: 114 DLVEKKSKNHIRWIG-----SDLSNFGAVPQQKKLQEELSDLSAME 154
Score = 37.7 bits (86), Expect = 0.046
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 28/170 (16%)
Query: 264 KSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKI----RRLYDIA 319
K+L+V +F + + T + + L +A I LD +K TK+ RR+YDI
Sbjct: 55 KALKVKRPRFDVSLVYLTRKFMDLVRSAPGGI-------LDLNKVATKLGVRKRRVYDIT 107
Query: 320 NVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSP---VIHFTPSDLEVRRSSKE 376
NVL +DL+ E+ K +W G ++S G+ P + SDL + +
Sbjct: 108 NVLDGIDLV-------EKKSKNHIRWIGSDLS--NFGAVPQQKKLQEELSDLSAMEDALD 158
Query: 377 ----NCAKNLFS-TRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKT 421
+CA+ LF T K N + + SI++ +I A +P +T
Sbjct: 159 ELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIAVKAPAET 208
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 46.6 bits (109), Expect = 1e-04
Identities = 54/237 (22%), Positives = 85/237 (35%), Gaps = 29/237 (12%)
Query: 403 SIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQL-------------- 448
S +SD + + APS P T K S++ + S + AA K +
Sbjct: 365 SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSS 424
Query: 449 ---EEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLS 505
EE SS +K K K VA P A+ L+ P+ P G S
Sbjct: 425 SSEEESSSSEEEKTK---------KMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDS 475
Query: 506 SAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEK 565
S+ + A+ +P + P + S SS ++ S DS++ EK
Sbjct: 476 SSSE---EEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Query: 566 AANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKED 622
S + + + G ++ E E K A ++ SGS KK K++
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQN 589
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 46.6 bits (109), Expect = 1e-04
Identities = 85/353 (24%), Positives = 129/353 (36%), Gaps = 46/353 (13%)
Query: 527 PTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAS--TRPGSLLP 584
PT + PP P TT +S + +T A T S+AS+S T G+ +P
Sbjct: 1917 PTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMP 1976
Query: 585 APE-RQGAKSRTREPAGER--GSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIP 641
P +G+ T P S AS L + P P
Sbjct: 1977 TPAYSEGSTPLTSMPLSTTLVVSSEASTLSTT---------------------PVDTSTP 2015
Query: 642 LTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLM 701
T + + +G + +P+ R ++P+AG +PV+++ + + + TP+
Sbjct: 2016 ATTSTEGSSSPTTAGGTSIQTSTPSER--TTPLAG-MPVSTTLVVSSEGNTLSTTPVD-- 2070
Query: 702 VSPTSVAAVPVGNSPALASSHPVPIQNPSSA---IVNFTLQHLGLISPNVQ-LSASPGSG 757
S T V +S A A + I PS + + L + SP LS +P
Sbjct: 2071 -SKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDS 2129
Query: 758 IVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGA---QQPVPV--- 811
PV E + GT +T D P S P +V + A PV
Sbjct: 2130 NSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTS 2189
Query: 812 TPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANK-TSLGTLFVPQRKLEVST 863
TP + A S T G + PTS+ EG+ TS+ +P E ST
Sbjct: 2190 TPVTNSTEARSSPTTSEGTSMPTSTPS---EGSTPFTSMPVSTMPVVTSEAST 2239
Score = 45.8 bits (107), Expect = 2e-04
Identities = 121/571 (21%), Positives = 195/571 (34%), Gaps = 99/571 (17%)
Query: 353 NTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHP------SLIKLVKSIES 406
+T ++PV TP SS A+ P R P S + + S S
Sbjct: 2946 STLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAS 3005
Query: 407 DRRKINSAPSSPIKTNKAESS----------------QNSAPFPSKMAQLAAICKMQLEE 450
+ + S+P+ T+ SS + S P S + +
Sbjct: 3006 TLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEAST 3065
Query: 451 QSS---ESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSA 507
S+ +S V S P P++ E + P L VP+ +P++S+
Sbjct: 3066 LSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTP-----LTGVPVSTTPVTSS 3120
Query: 508 VPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLS-PTVCTTHSSK-----------ATGS 555
L P S + T+AH S T +G S PT + S S
Sbjct: 3121 AISTLSTTPVDTSTPVTTS-TEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSS 3179
Query: 556 KDSTDA-----TTEKAANDTSKASASTRPGSLLP-APERQGAKSRTREPAGER--GSKRA 607
+DST + T+ T S++T G+ +P + +G T P S A
Sbjct: 3180 EDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA 3239
Query: 608 SMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNH 667
S+L + P PLT +S A S E +S +
Sbjct: 3240 SILSTT---------------------PVDSNTPLT--TSTEASSSPPTAEGTSMPT--- 3273
Query: 668 RIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVP---VGNSPALASSHPV 724
S+P G P+TS ++ S + L + TS +SP +A +
Sbjct: 3274 ---STPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM 3330
Query: 725 PIQN---PSSAIVNFTLQHLGLISPNVQ-LSASPGSGIVPVSPRIESVNVAPENA-GTQQ 779
P S+ + N + ++S LS +P PV+ E+ +++P A GT
Sbjct: 3331 PTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEA-SLSPTTAEGTSI 3389
Query: 780 GRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPT------KP 833
++ + P S P + V+ + TP S + + PT P
Sbjct: 3390 PTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLP 3449
Query: 834 TSSSCMDFEGANKTSLGTL-FVPQRKLEVST 863
TS++ EG+ S+ L P E ST
Sbjct: 3450 TSTTS---EGSTPLSIMPLSTTPVASSEAST 3477
Score = 44.7 bits (104), Expect = 4e-04
Identities = 108/513 (21%), Positives = 170/513 (33%), Gaps = 86/513 (16%)
Query: 353 NTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKIN 412
+T ++PV P SS A+ P+ P LV ++ + +
Sbjct: 2887 STLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAS 2946
Query: 413 SAPSSPIKTN-----KAESSQN-------SAPFPSKMAQLAAICKMQLEEQSSESRQKVK 460
+ ++P+ T AE+S + S P + + + M + S +
Sbjct: 2947 TLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAST 3006
Query: 461 VQLARSGPCKPVAPL----DPPVNAE---MELTAPSLIQPLGMVPLIPSPLSSAVPLILP 513
+ + PV P AE + ++ PS G PL P+S+ P+ +P
Sbjct: 3007 LSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSE----GSTPLTSIPVSTT-PVAIP 3061
Query: 514 QAPSGPSYAI-----YLQPTQAHQSVTPPQGLSPTVCTTH--SSKATGSKDSTDATTEKA 566
+A + + + + T+ S TP +G S + T S+ TG ST T A
Sbjct: 3062 EASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSA 3121
Query: 567 ANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGL 626
+ S T P A S P G+ + GS
Sbjct: 3122 ISTLSTTPVDTST----PVTTSTEAHS---SPTTSEGTSMPTSTPSEGST---------- 3164
Query: 627 ENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSS--- 683
PLT + ++L S LS S+P+ TSS
Sbjct: 3165 --------------PLTY---MPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTA 3207
Query: 684 ELTAV--NFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHL 741
E T++ + PS +TPL +VPV N+P +S + P + T
Sbjct: 3208 EGTSIPTSTPSEGMTPL---------TSVPVSNTPVASSEASILSTTPVDSNTPLTTSTE 3258
Query: 742 GLISPNVQLSAS-----PGSGIVPV-SPRIESVNVAPENAGTQQGRATNYDSPVPGQSQP 795
SP S P G P+ S + + VA T + +PV SQ
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318
Query: 796 NGQSVAVTGAQQPVPVTPKGS-QLVAESFFRTP 827
+ G P +GS L SF TP
Sbjct: 3319 SSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTP 3351
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/357 (20%), Positives = 145/357 (40%), Gaps = 23/357 (6%)
Query: 493 PLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKA 552
PL +P+ +P++++ L P + + + T S TP +G S + +T S +
Sbjct: 1456 PLKSIPVSNTPVANSEASTLSTTPVDSNSPV-VTSTAVSSSPTPAEGTSIAI-STPSEGS 1513
Query: 553 TGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLED 612
T +TT A+++ + S + S Q + S P G+ +
Sbjct: 1514 TALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSS----PTTADGTSMQTSTYS 1569
Query: 613 SGSKKKFKEDLKGLENVS--ATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIY 670
GS + + VS A + + TQ ++ E+ S S+++ +
Sbjct: 1570 EGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTA-STEASSSTTAEGSSMTISTPSE 1628
Query: 671 SSPIAGVIPVTSSELTAVNFPSFHVTPLKL---MVSPTSVAAVPVGNSPALASSHPVPIQ 727
SP+ IPV+++ + + + TP+ +++ T V++ P +PA +S P
Sbjct: 1629 GSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSP---TPAEGTSMPTSTY 1685
Query: 728 NPS-SAIVNFTLQHLGLISPNVQ-LSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNY 785
+ + + T++ + S + LS +P PV+ E+ + + GT +T
Sbjct: 1686 TEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPS 1745
Query: 786 D-----SPVPGQSQPNGQSVAVTGAQQPVPV-TPKGSQLVAESFFRTPGGPTKPTSS 836
+ + +P + P S A T + P+ TP + A S T G + PTS+
Sbjct: 1746 EGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTST 1802
Score = 40.0 bits (92), Expect = 0.009
Identities = 107/524 (20%), Positives = 178/524 (33%), Gaps = 60/524 (11%)
Query: 353 NTSGSSPVIHFTPSDLEVRRSSKENCAKNLFS-----TRGKPNFTRHPSLIKLVKSIESD 407
+T ++PV TP +S A+ T G T P LV S E+
Sbjct: 647 STLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEAS 706
Query: 408 RRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSG 467
+S T E+S S+P + A + E + + V L S
Sbjct: 707 TLSTTPVDTSTPVTTSTEAS--SSPTTADGASMPT--STPSEGSTPLTSMPVSKTLLTSS 762
Query: 468 PCKPVA--PLDPPVNAEMELTA---PSLIQPLGM---VPLIPSPLSSAVPLILPQAPSGP 519
++ PLD + A P+ + M P SPL +++P+ + S
Sbjct: 763 EASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE 822
Query: 520 SYAIYLQP----------TQAHQSVTPPQGLS-PTVCTTHSSKATGSKDSTDATTEKAAN 568
+ + P T+ S TP +G S PT +T+S T +TT A +
Sbjct: 823 ASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPT--STYSEGRTPLTSMPVSTTLVATS 880
Query: 569 DTSKASAS--------TRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFK 620
S S + T +P S GE GS + + DS +
Sbjct: 881 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGE-GSTPLTSMPDSTTPVVSS 939
Query: 621 EDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPV 680
E +SAT P P+T +S A S + E +S + S+P G P+
Sbjct: 940 E----ARTLSAT--PVDTSTPVT--TSTEATSSPTTAEGTSIPT------STPSEGTTPL 985
Query: 681 TSSELT---AVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFT 737
TS+ ++ N + ++ + + + + P A +P PS T
Sbjct: 986 TSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT 1045
Query: 738 LQHLGLI----SPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQS 793
+ S LS +P PV+ ++ + + GT +T + P S
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105
Query: 794 QPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSS 837
P + V+ + TP + + + PT +S
Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTS 1149
Score = 40.0 bits (92), Expect = 0.009
Identities = 99/444 (22%), Positives = 154/444 (34%), Gaps = 60/444 (13%)
Query: 478 PVNAEMELTAPSLIQPLGMVPLIPSPLS--SAVPLILPQAPSGPSYAIYLQPTQAHQSVT 535
P + E + P P+ +P++ S S SA P + P S PT A +
Sbjct: 2211 PTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATP-VDTSTPVTTSTEATSSPTTAEGTSI 2269
Query: 536 PPQGLSP------TVCTTHSSKATGSKDSTDATTEKAAND--TSKASASTRP----GSLL 583
P LS ++ +H+ A S+ ST +TT +N T+ AS+ P G+ +
Sbjct: 2270 PTSTLSEGTTPLTSIPVSHTLVAN-SEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSM 2328
Query: 584 P-APERQGAKSRTREPAG-------ERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFP 635
P + +G TR P E + + + S + + T P
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388
Query: 636 -SGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTA------V 688
S Y T +S+ ++ +S S S+P+ +SS TA
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPT 2448
Query: 689 NFPSFHVTPLKLM-VSPTSVAAVPVG--------------------NSPALASSHPVPIQ 727
+ PS TPL M VS T V + G +SP A VPI
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIS 2508
Query: 728 NPSSA---IVNFTLQHLGLISPNVQ-LSASPGSGIVPVSPRIESVNVAPENAGTQQGRAT 783
S + + + + SP LS +P PV E + A GT +T
Sbjct: 2509 TASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTST 2568
Query: 784 NYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSC-MDFE 842
+ P +S P + + TP + + + T PT +S +
Sbjct: 2569 YSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP 2628
Query: 843 GANKTSLGTLFV---PQRKLEVST 863
TSL ++ V P E ST
Sbjct: 2629 SEVSTSLTSILVSTMPVASSEAST 2652
Score = 39.7 bits (91), Expect = 0.012
Identities = 68/319 (21%), Positives = 124/319 (38%), Gaps = 33/319 (10%)
Query: 528 TQAHQSVTPPQ-GLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAP 586
T SVT G+S T T S+ T S+ ++D+TT ++ +S +T G+ +P
Sbjct: 92 TSIESSVTSDTPGVSSTRMTPTESRTT-SESTSDSTTLFPSSTEDTSSPTTPEGTDVPMS 150
Query: 587 ERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCS 646
P+ E S + + + L E ++ + PLT +
Sbjct: 151 T----------PSEESISSTMAFVSTA--------PLPSFEAYTSLTYKVDMSTPLT--T 190
Query: 647 SLGAESILSGKENSSALSPNHRIYSSPI----AGVIPVTSSE-LTAVNFPSFHVTPLKLM 701
S A S + E+++ + S+P+ A + V SSE +T + P TP+ +
Sbjct: 191 STQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS 250
Query: 702 VSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQ-LSASPGSGIVP 760
+S G P+L++S P S+ + L + ++S LS +P + +P
Sbjct: 251 AQASSSPTTAEG--PSLSNSAP---SGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIP 305
Query: 761 VSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVA 820
V E+ + GT +T + P S P T + +TP + +
Sbjct: 306 VITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLV 365
Query: 821 ESFFRTPGGPTKPTSSSCM 839
+ PT ++S +
Sbjct: 366 TTSTEPSSLPTTAEATSML 384
Score = 38.9 bits (89), Expect = 0.021
Identities = 101/506 (19%), Positives = 168/506 (33%), Gaps = 68/506 (13%)
Query: 346 TGPEISPNTS--GSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKS 403
T P +S S ++PV TP +S A+ + P+ + P +KS
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP-----LKS 1459
Query: 404 IESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQL 463
I + ++ +S + T +S+ S + A+ SS +
Sbjct: 1460 IPVSNTPVANSEASTLSTTPVDSN-------SPVVTSTAV--------SSSPTPAEGTSI 1504
Query: 464 ARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPS-PLSSAVPLILPQAPSGPSYA 522
A S P + L + A S I L P + S P+++ QA S P+ A
Sbjct: 1505 AISTPSEGSTALTS-IPVSTTTVASSEINSLSTTPAVTSTPVTT-----YSQASSSPTTA 1558
Query: 523 --IYLQPTQAHQSVTPPQGLSPTVCTTHSSKAT-------GSKDSTDATTEKAANDTSKA 573
+Q + + TP L + SS+A SK A+TE +++ T++
Sbjct: 1559 DGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEG 1618
Query: 574 SASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLEN-VSAT 632
S+ T +P T A S ++ DS S ++ T
Sbjct: 1619 SSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGT 1678
Query: 633 LFP-SGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFP 691
P S Y T +S+ + S LS S+P+ SS T+
Sbjct: 1679 SMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTS 1738
Query: 692 SFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLS 751
+ TP + T + ++PV +P L+S LS
Sbjct: 1739 MPNSTPSE---GTTPLTSIPVSTTPVLSSEAST-------------------------LS 1770
Query: 752 ASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPV 811
A+P PV+ E+ + GT +T + P S P ++ +
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLST 1830
Query: 812 TPKGSQLVAESFFRTPGGPTKPTSSS 837
TP S + PT +S
Sbjct: 1831 TPVDSNSPVVTSTAVSSSPTPAEGTS 1856
Score = 38.5 bits (88), Expect = 0.027
Identities = 113/552 (20%), Positives = 193/552 (34%), Gaps = 79/552 (14%)
Query: 353 NTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKIN 412
+T ++PV TP SS A+ P+ P V + +
Sbjct: 2415 STHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAG 2474
Query: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472
+ ++P+ T+ ++ A S A + + S S + ++ + P
Sbjct: 2475 TLSTTPVDTSTPMTTSTEA---SSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPE 2531
Query: 473 A------PLDP--PVNAEMELTA----------PSLIQPLGMVPLIPSPLSSAVPLILPQ 514
A P+D PV E+++ P+ G PL P+S+
Sbjct: 2532 ASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTK------- 2584
Query: 515 APSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKAS 574
P S A L T S+ T T SS T +KD++ + + TS S
Sbjct: 2585 -PLASSEASTLSTTPVDTSIPV------TTSTETSSSPTTAKDTSMPISTPSEVSTSLTS 2637
Query: 575 ASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLF 634
S +P + A + + P R +++ S +G ++T
Sbjct: 2638 ILV---STMPVASSE-ASTLSTTPVDTR-----TLVTTSTGTSSSPTTAEGSSMPTST-- 2686
Query: 635 PSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTA------V 688
P PLT L + ++L+ E +S LS S+P+ +SS TA +
Sbjct: 2687 PGERSTPLTNI--LVSTTLLANSE-ASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRI 2743
Query: 689 NFPSFHVTPL-KLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPN 747
+ PS TPL ++VS VA+ A +P+ + A + T + + +
Sbjct: 2744 STPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTS 2803
Query: 748 VQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQ 807
S +PV+ VA AGT + +PV ++ + G
Sbjct: 2804 TPSETSTPLTSMPVN----HTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVV 2859
Query: 808 PVPVTPKGSQLV--------------AESFFRTPGGPTKPTSSSCMDFEGANK--TSLGT 851
P+ +GS L+ A + TP + P ++S EG++ T+ GT
Sbjct: 2860 PISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTST---EGSSSPTTAEGT 2916
Query: 852 LFVPQRKLEVST 863
EVST
Sbjct: 2917 SMPISTPSEVST 2928
Score = 38.1 bits (87), Expect = 0.036
Identities = 107/533 (20%), Positives = 186/533 (34%), Gaps = 58/533 (10%)
Query: 346 TGPEISPN--TSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKS 403
T P +S T ++PV TP +S A+ P+ P V
Sbjct: 933 TTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSH 992
Query: 404 IESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSE-SRQKVKVQ 462
+ ++ ++P+ +N ++ A P A+ ++ E S+ +R V
Sbjct: 993 TLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTT 1052
Query: 463 LARSGPCKPVA--PLDP--PVNAEMELTA----------PSLIQPLGMVPLIPSPLSSAV 508
+ S ++ P D PV + ++ P+ G PL P+S+ +
Sbjct: 1053 MVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRL 1112
Query: 509 PL-----ILPQAPSGPSYAIYLQPTQAHQSVTPPQGLS-----PTVCTTHSSKATGSKD- 557
+ L P S + T+A S T +G S P+ TT + S
Sbjct: 1113 VVSSEASTLSTTPVDTSIPVTTS-TEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTL 1171
Query: 558 --STDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGS 615
S++A T SK +T + P P + T P GER + SM
Sbjct: 1172 VVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP-GERSTPLTSM------ 1224
Query: 616 KKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIA 675
+ E + + P P+T + + + ++L + S +
Sbjct: 1225 -PVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA---EGTSLPTSTTSEGSTLL 1280
Query: 676 GVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPI----QNPSS 731
IPV+++ +T+ + TP+ + V +PA +S P + P +
Sbjct: 1281 TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLT 1340
Query: 732 AI-VNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVP 790
+I VN TL IS LS +P PV+ E+ + + GT + + P
Sbjct: 1341 SIPVNTTLVASSAISI---LSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP 1397
Query: 791 GQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEG 843
S P + V+ + TP + TPG + +SS EG
Sbjct: 1398 LTSIPVSTTPVVSSEASTLSATPVDTS--------TPGTTSAEATSSPTTAEG 1442
Score = 37.7 bits (86), Expect = 0.046
Identities = 77/411 (18%), Positives = 145/411 (35%), Gaps = 51/411 (12%)
Query: 478 PVNAEMELTAPSLIQPLGMVPLIPS--------PLSSAVPLILP-QAPSGPSYA--IYLQ 526
P A E + P PL ++ S P+ ++ P + S P+ A +Q
Sbjct: 1976 PTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQ 2035
Query: 527 PTQAHQSVTPPQGLSPTVCTTHSSKA-TGSKDSTDATTEKAANDTSKASASTRPGSLLPA 585
+ + TP G+ + SS+ T S D+ T+ + + +SA+ S+ +
Sbjct: 2036 TSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTIS 2095
Query: 586 PERQGAKSRTREPAGER--GSKRASMLE----DSGSKKKFKEDLKG--LENVSATLFPSG 637
+G+ T P S AS L DS S ++ + ++ S
Sbjct: 2096 APSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTST 2155
Query: 638 YLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVN-------- 689
Y T +S+ + + S LS S+P+ SS T+
Sbjct: 2156 YSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP 2215
Query: 690 ------FPSFHVTPLKLMVSPTS-VAAVPVG------------NSPALASSHPVP---IQ 727
F S V+ + ++ S S ++A PV +SP A +P +
Sbjct: 2216 SEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 2275
Query: 728 NPSSAIVNFTLQHLGLISPNVQ-LSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYD 786
++ + + + H + + V LS +P P + E+ + P GT +T+ +
Sbjct: 2276 EGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSE 2335
Query: 787 SPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSS 837
P P ++ + + TP + ++ + PT +S
Sbjct: 2336 GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTS 2386
Score = 36.2 bits (82), Expect = 0.14
Identities = 108/525 (20%), Positives = 181/525 (34%), Gaps = 66/525 (12%)
Query: 357 SSPVIHFTPSDLEVRRSSKENCAK-----NLFSTRGKPNFTRHPSLIKLVKSIESDRRKI 411
++PV TP + + SS A+ N + G TR P + LV S E+
Sbjct: 238 TTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLST 297
Query: 412 NSAPSS-PIKTNKAESS----------------QNSAPFPSKMAQLAAICKMQLEEQSSE 454
A ++ P+ T+ SS + S P S A + E S+
Sbjct: 298 TPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVAT---SEMSTL 354
Query: 455 SRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLS--------- 505
S V + +P + P AE S + G PL P+S
Sbjct: 355 SITPVDTSTLVTTSTEPSSL---PTTAEATSMLTSTLSE-GSTPLTNMPVSTILVASSEA 410
Query: 506 ---SAVPLILPQAPSGPSYAIYLQPTQAHQSV---TPPQGLSPTVCTTHSSKATGSKDST 559
S +P+ + S A T S+ TP +G +P S+ S +++
Sbjct: 411 STTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEAS 470
Query: 560 DATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKF 619
+ +T + T + + ST S P E + T GS + + S
Sbjct: 471 NLSTTPVDSKT-QVTTSTEASSSPPTAEVNSMPTSTPS----EGSTPLTSMSVSTMPVAS 525
Query: 620 KEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIP 679
E +S T P P+T S + S + +P+ S+P+ + P
Sbjct: 526 SE----ASTLSTT--PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEG--STPLTNM-P 576
Query: 680 VTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQ 739
V++ + + + TP T+ + ++ A +S P + +
Sbjct: 577 VSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSV 636
Query: 740 HLGLISPNVQ--LSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQP-- 795
L++ + LS +P PV+ E+ + + GT +T + P S P
Sbjct: 637 STTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVN 696
Query: 796 ---NGQSVAVTGAQQPVPV-TPKGSQLVAESFFRTPGGPTKPTSS 836
S A T + PV TP + A S T G + PTS+
Sbjct: 697 TTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTST 741
Score = 33.9 bits (76), Expect = 0.67
Identities = 71/359 (19%), Positives = 138/359 (38%), Gaps = 39/359 (10%)
Query: 478 PVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPP 537
P ++ E T P P+ P++ S +++ L P S + T+A S T
Sbjct: 3390 PTSSPSEGTTPLASMPVSTTPVVSSEVNT-----LSTTPVD-SNTLVTTSTEASSSPTIA 3443
Query: 538 QGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTRE 597
+G S TT S +T +TT A+++ S S + S P + + +
Sbjct: 3444 EGTSLPTSTT-SEGSTPLSIMPLSTTPVASSEASTLSTTPVDTS---TPVTTSSPTNSSP 3499
Query: 598 PAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGK 657
E S S + + L N+ + P + ++ S+L +
Sbjct: 3500 TTAEVTSMPTSTAGEGSTP---------LTNMPVSTTP----VASSEASTLSTTPV---- 3542
Query: 658 ENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPA 717
++++ ++ + + SSP + VT+ ++ + S +T + L + + + ++P+
Sbjct: 3543 DSNTFVTSSSQASSSP--ATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600
Query: 718 LASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGT 777
+ S PV S++ T + + + S I+PVS + +V AGT
Sbjct: 3601 VDRSTPVTTSTQSNSTP--TPPEVITLPMSTPSEVSTPLTIMPVS----TTSVTISEAGT 3654
Query: 778 QQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSS 836
+ +PV +Q + V G P+ +GS + P T+ TSS
Sbjct: 3655 ASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLT----TMPVSTTRVTSS 3709
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 45.4 bits (106), Expect = 2e-04
Identities = 87/420 (20%), Positives = 145/420 (34%), Gaps = 58/420 (13%)
Query: 405 ESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLA 464
E R + +SP T AE + + PS + L+ +++S+ K L
Sbjct: 7007 EISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLT---LDTSTTKSQAKTHSTLT 7063
Query: 465 RSGPCKPVAPLDPPVNAEMEL-TAPSLIQPLGMVPLI-------PSPLSSAVPLILPQAP 516
+ P + L +M ++PSL P + L+ P P+SS +P+ + +P
Sbjct: 7064 QRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSP 7123
Query: 517 SGPSYAIYLQPTQA----HQSVTPPQGLSPTVCTTHSSKATGSKDSTD------ATTEKA 566
+ + P H S P + T + T KD+T+ +T A
Sbjct: 7124 LPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAA 7183
Query: 567 ANDTSKASASTRPGSLLPAPERQGAKS---------------------RTREPAGERGSK 605
+N +S P S L E A S T E S
Sbjct: 7184 SNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISS 7243
Query: 606 RASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSA--L 663
+ L ++GS + ++ +S + I T+ +S SI E++ +
Sbjct: 7244 LSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEI 7303
Query: 664 SPNHRIYSSPIAGVIPVTSSELTAVNFPS-------------FHVTPLKLMVSPTSVAAV 710
S +I P + ++ SSE+T S TP ++ T +
Sbjct: 7304 STTRKIIKFPTSPIL-AESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRL 7362
Query: 711 PVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNV 770
P L S + PSS V T +S + +S SP S +P S S +V
Sbjct: 7363 PHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASV 7422
Score = 39.7 bits (91), Expect = 0.012
Identities = 93/430 (21%), Positives = 162/430 (37%), Gaps = 85/430 (19%)
Query: 422 NKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNA 481
N+ E S SAP+ ++M +S S +K + S + + LD +N
Sbjct: 3870 NEKEKSTPSAPWITEM-------------MNSVSEDTIKEVTSSSSVLRTLNTLD--INL 3914
Query: 482 EMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLS 541
E T+ + + PS ++ I P + + A S P S
Sbjct: 3915 ESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSAS 3974
Query: 542 -----PTVCTTHSSKATGSK------DSTDATTEKAANDTSKA--------SASTRPGSL 582
P V T+ +A S +ST A TE + T + ++ST S+
Sbjct: 3975 SKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSI 4034
Query: 583 LPAPERQGAKSRTREPAGE-RGSKRAS---MLEDSGSKKKFKEDLKGLENVSATLFPSGY 638
+ +P G+ + T+ P E SKR S + + S E + L N A + SG
Sbjct: 4035 ISSP---GSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPA-MTESGG 4090
Query: 639 LIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAV---------- 688
+I Q S GA S+ + ++SA + +P+A T SE T +
Sbjct: 4091 MILAMQTSPPGATSLSAPTLDTSATAS---WTGTPLATTQRFTYSEKTTLFSKGPEDTSQ 4147
Query: 689 --------NFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQH 740
S + P+ SP+++ G+SP SS P P +++
Sbjct: 4148 PSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSP---SSTP-----PVTSVFLSETSG 4199
Query: 741 LGLISPNVQLSASPGSGIVP--------------VSPRIESVNVAPENAGTQQGRATNYD 786
LG + ++S PG+ + P S ++++ + + A T ++
Sbjct: 4200 LGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEY 4259
Query: 787 SPVPGQSQPN 796
SP+PG ++P+
Sbjct: 4260 SPIPGHTKPS 4269
Score = 36.6 bits (83), Expect = 0.10
Identities = 119/544 (21%), Positives = 191/544 (35%), Gaps = 54/544 (9%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSK---ENCAKNLFSTRGKPNFTRHPSLIKLVK 402
TG + +S +S S + R+S ++ + S+ G + + H + K
Sbjct: 2756 TGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFS 2815
Query: 403 SIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQ 462
S+ S I TN+ ++Q++AP + +A + +S S K
Sbjct: 2816 SLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFAS 2875
Query: 463 LARSGPC----KPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSG 518
L + P + + ++ + SL P + IP +S L ++P
Sbjct: 2876 LTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK 2935
Query: 519 PSYAIYLQPTQA-----HQSV----TPPQGLSPTVCTTHSSKAT-GSKDSTDATTEKAAN 568
A + T+A QS TP SP++ T G+ D A+ +
Sbjct: 2936 NPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYP 2995
Query: 569 DTSKASA---STRPGSLLPAPERQGAKSR---TREPAGERGSKRASMLEDSGSKKKFKED 622
D SKAS+ ST S L G +R + P K S L + S +
Sbjct: 2996 DPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSL 3055
Query: 623 LKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTS 682
G S P+ + T +L S L N S P S IA T+
Sbjct: 3056 FLG---PSMARQPNILVHLQTSALTLSPTSTL----NMSQEEPPELTSSQTIAEEEGTTA 3108
Query: 683 SELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLG 742
T PS T L + SPT A + ASS VP + + TL
Sbjct: 3109 ETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTI 3168
Query: 743 LIS------------PNVQLSASPGSGIVPVSPRIES---VNVAPENAGTQQGRATNYDS 787
+S P + +SP +G P SP + + + + E + + + R+T +S
Sbjct: 3169 KMSSQAAQGNSTWPAPAEETGSSP-AGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNS 3227
Query: 788 P--VPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGAN 845
P P + P +V +PV + + S P G T PT S +
Sbjct: 3228 PWKTPETTVPMETTV------EPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATE 3281
Query: 846 KTSL 849
+ SL
Sbjct: 3282 RVSL 3285
Score = 36.2 bits (82), Expect = 0.14
Identities = 101/477 (21%), Positives = 177/477 (37%), Gaps = 65/477 (13%)
Query: 353 NTSGSSPVIHFTPSDLEVRRSSKENCAKNLFST-RGKPNFTRHPSLIKLVKSIESDRRKI 411
+TS + P + +P + E R + + A+ + R PNF+ H S
Sbjct: 10662 DTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHES--------------- 10706
Query: 412 NSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKP 471
++ PS I T+ + ++ P + + Q+ ++ + G K
Sbjct: 10707 DATPS--IATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKT 10764
Query: 472 VAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLI------LPQAPSGPSYAIYL 525
+A L A+ P+ + L+ S ++S L +P P+ + L
Sbjct: 10765 IASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSL 10824
Query: 526 QPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKA----SASTR-PG 580
VT P SPTV T S D+T + T ++S A + ST PG
Sbjct: 10825 --------VTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPG 10876
Query: 581 SLLPAPERQGAKSRTREP-----AGE---RGSKRASMLEDSGSKKKFKEDLKGLENVSAT 632
+ P A T P GE S S E++ S G+ V +
Sbjct: 10877 VVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTS 10936
Query: 633 LFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYS-SPIAGVIPVTSSELTAVNFP 691
L S + T L L E + +++ +H + S + V+P +T++
Sbjct: 10937 LVTSSRAVTSTTIPILTFS--LGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVAS 10994
Query: 692 SFHVTPLKLMVSPT-SVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQL 750
S VT L PT +++ +P++A+SH SS + + + G+++ V
Sbjct: 10995 SRAVTSTTL---PTLTLSPGEPETTPSMATSHGA---EASSTVPTVSPEVPGVVTSLVTS 11048
Query: 751 SASPGSGIVPVSPRIESVNVAPENAGTQQGRATNY----DSPVPGQSQPNGQSVAVT 803
S+ S +P ++ ++P T AT++ S VP + G S VT
Sbjct: 11049 SSGVNSTSIP------TLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVT 11099
Score = 35.4 bits (80), Expect = 0.23
Identities = 68/323 (21%), Positives = 114/323 (35%), Gaps = 46/323 (14%)
Query: 546 TTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPA--GERG 603
TT T S + S S++T L A AK R E G +
Sbjct: 2056 TTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQN 2115
Query: 604 SKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSAL 663
+ +++ D+ S E G S P ++ + S +SG + S
Sbjct: 2116 TAASTLNTDASSVTGLSETPVGASISSEVPLPM----------AITSRSDVSGLTSESTA 2165
Query: 664 SPNHRIYSSPIAGV-IPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSH 722
+P+ SS AG + T S T+ + SF + VS +P+G+ P +
Sbjct: 2166 NPSLGTASS--AGTKLTRTISLPTSESLVSFRMNKDPWTVS------IPLGSHPTTNTET 2217
Query: 723 PVPIQNP--------SSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPEN 774
+P+ + +S +++ I P V S SP + + +S E +
Sbjct: 2218 SIPVNSAGPPGLSTVASDVIDTPSDGAESI-PTVSFSPSPDTEVTTISHFPEKTTHSFRT 2276
Query: 775 AGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPV---------TPKGSQLVAESFFR 825
+ T+ +P+PG + S TGA + + P S +V + F
Sbjct: 2277 ISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASF- 2335
Query: 826 TPGGPTKPTSSSCMDFEGANKTS 848
TS+ +D E KTS
Sbjct: 2336 ------TETSTVSLDNETTVKTS 2352
Score = 35.4 bits (80), Expect = 0.23
Identities = 36/168 (21%), Positives = 71/168 (42%), Gaps = 8/168 (4%)
Query: 701 MVSPTSVAAVPVGN-SPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIV 759
++SP+ + PV + SP S P+P+ ++++ T LG SP S+ P
Sbjct: 5634 LMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLS-- 5691
Query: 760 PVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLV 819
SP E + + A T+ A+ + + G S++ +Q VP S+
Sbjct: 5692 --SPTQERLTTYKDTAHTEAMHASMHTNTAVANV---GTSISGHESQSSVPADSHTSKAT 5746
Query: 820 AESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH 867
+ G T ++S+ FE +T + +P + ++E+++
Sbjct: 5747 SPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEIN 5794
Score = 34.7 bits (78), Expect = 0.39
Identities = 58/290 (20%), Positives = 105/290 (36%), Gaps = 57/290 (19%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCA------KNLFSTRGKPNFTRHPSLIK 399
+ P + +T G + V+ TP+ LE RR E + + + G + T+ +++
Sbjct: 7794 SSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLS 7853
Query: 400 LVKS---IESDRRKINSAP--------------------SSPIKTNKAESSQNSAPFP-- 434
V + E + + S P +SP+ T AE + N+ P
Sbjct: 7854 KVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLG 7913
Query: 435 ----------SKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEME 484
+ + + + S S+ L R GP + V+ + PP+ +E
Sbjct: 7914 ATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMST---LMRRGP-EDVSWMSPPL---LE 7966
Query: 485 LTAPSLIQPLGMVPLIPSPLSSAVPLILPQAP--------SGPSYAIYLQPTQAHQSVTP 536
T PS PSP+SS +P + +P SG + + +
Sbjct: 7967 KTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNS 8026
Query: 537 PQGLSPT-VCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPA 585
P LS T V +S+ T + T ++ + D +S+ S + A
Sbjct: 8027 PANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLA 8076
Score = 31.6 bits (70), Expect = 3.3
Identities = 105/500 (21%), Positives = 179/500 (35%), Gaps = 82/500 (16%)
Query: 388 KPNFTRHPSLIKLVKSIESDR-RKINSAPSSPIKTNKAESSQN---------SAPFPSKM 437
KP++T S+I S++S R+ S +P+ T SS S P +
Sbjct: 669 KPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIP--L 726
Query: 438 AQLAAICKMQLEEQSSESRQKVKVQLARSGP-----CKPVAPLDPPVNAEMELTAPSLIQ 492
A++ + ++ S+ S K + P KP + + + T+P ++
Sbjct: 727 LSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVR 786
Query: 493 PLGMVPLIPSP----LSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLS-PTVC-- 545
PSP + +V + A + S I+ T +S P LS P+V
Sbjct: 787 NATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGV 846
Query: 546 -TTHSSKATG-----SKDSTDATTEKAAND---------TSKASASTRPGSLLPA----P 586
TT SS S + T+ T+ + + T+ AS S P + P P
Sbjct: 847 KTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSV-PTPVFPTMDTWP 905
Query: 587 ERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSAT--------LFPSGY 638
R S + + R + S+ +GS L G +S T P
Sbjct: 906 TRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQST 965
Query: 639 LIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSS-ELTAVNFPSFHVTP 697
P T + ++SA S + + S P TSS E T++ PS +
Sbjct: 966 TWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTS--PATSSMEATSIREPSTTILT 1023
Query: 698 LKLMVSPTSVAA----VPVGNS----PALASSH-PVPIQNPSSAIVNFTLQHLGL---IS 745
+ P S+A +P+G L +SH P+ S ++FT+ + +S
Sbjct: 1024 TETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVS 1083
Query: 746 PNVQLSASPGSGIVPVSPRIESVNV---------------APENAGTQQGRATNYDSPVP 790
P+ + A+ S S +++ + +A T Q AT+ SP P
Sbjct: 1084 PSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDP 1143
Query: 791 GQSQPNGQSVAVTGAQQPVP 810
G ++ + + P P
Sbjct: 1144 GSARSTWLGILSSSPSSPTP 1163
Score = 31.6 bits (70), Expect = 3.3
Identities = 48/167 (28%), Positives = 70/167 (41%), Gaps = 30/167 (17%)
Query: 673 PIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVP--------VGNSPALASSHPV 724
P IP+T++E T+ SF TPL + ++ S+ VP N AL
Sbjct: 2645 PDTPAIPLTATEPTSSLATSFDSTPL-VTIASDSLGTVPETTLTMSETSNGDALVLK--- 2700
Query: 725 PIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIE-SVNVAPEN--AGTQQGR 781
+ NP +I T+Q + SP S SP + P + E S+ VA AGT
Sbjct: 2701 TVSNPDRSIPGITIQGV-TESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTT--- 2756
Query: 782 ATNYDSPVPGQSQPNGQSVAVTGAQ------QPVPVTPKGSQLVAES 822
S V QS N ++ A+ + +P+T GSQ +A S
Sbjct: 2757 ----GSLVFSQSSENSETTALVDSSAGLERASVMPLT-TGSQGMASS 2798
Score = 30.4 bits (67), Expect = 7.4
Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Query: 705 TSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPR 764
TS A+ V +S + +P+S++V T Q LG++S + S S G + S +
Sbjct: 43 TSTGAIVVTEHTLPFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRG---MTHSEQ 99
Query: 765 IESVNVAPENAGTQQGRATNY--DSPVPGQSQPNGQSVAVTG 804
S +++P+ GT + NY S V G S P ++ + G
Sbjct: 100 RTSPSLSPQVNGTP---SRNYPATSMVSGLSSPRTRTSSTEG 138
Score = 30.0 bits (66), Expect = 9.7
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 15/79 (18%)
Query: 703 SPTSVAAVPVGNS----PALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGI 758
SP SV +S PA+ S PVP P S S V L++ P SG+
Sbjct: 6501 SPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRP-----------SSPVHLTSLPTSGL 6549
Query: 759 VPVSPRIESVNVAPENAGT 777
V + + SV P N G+
Sbjct: 6550 VKTTDMLASVASLPPNLGS 6568
Score = 30.0 bits (66), Expect = 9.7
Identities = 29/129 (22%), Positives = 56/129 (43%), Gaps = 8/129 (6%)
Query: 660 SSALSPNHRIYSSPIAGVIP----VTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNS 715
SS+L P+ + S P++ +P T S +T++ PS +T L SP + P S
Sbjct: 6802 SSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLS 6861
Query: 716 PALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSAS-PGSGIVPVSPRIESVNVAPEN 774
++SH + + + + + NV+ ++S GS ++ ++ AP +
Sbjct: 6862 ---STSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMD 6918
Query: 775 AGTQQGRAT 783
+ G T
Sbjct: 6919 TTSTMGHTT 6927
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 45.4 bits (106), Expect = 2e-04
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 25/188 (13%)
Query: 411 INSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCK 470
+N P + T SQ++ P K++ L + E+ ++ + + PC
Sbjct: 245 VNKDPELGVGTLPEHDSQDAGPIVPKISGL----ERSQEKSQDCCKEPIFEPVVLKDPCP 300
Query: 471 PVAPLDPPVNAEMELTAPS----LIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQ 526
VA P E +L APS L+Q P P PLS+ Q P GP A LQ
Sbjct: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQ-PPPLST-------QPPQGPPEA-QLQ 351
Query: 527 PTQAHQSVTPPQGLSPT--------VCTTHSSKATGSKDSTDATTEKAANDTSKASASTR 578
P Q PP+ SPT H S + S+ + + + ++ +S S+
Sbjct: 352 PAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSST 411
Query: 579 PGSLLPAP 586
P PAP
Sbjct: 412 PAKTQPAP 419
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 45.4 bits (106), Expect = 2e-04
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 25/188 (13%)
Query: 411 INSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCK 470
+N P + T SQ++ P K++ L + E+ ++ + + PC
Sbjct: 245 VNKDPELGVGTLPEHDSQDAGPIVPKISGL----ERSQEKSQDCCKEPIFEPVVLKDPCP 300
Query: 471 PVAPLDPPVNAEMELTAPS----LIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQ 526
VA P E +L APS L+Q P P PLS+ Q P GP A LQ
Sbjct: 301 QVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQ-PPPLST-------QPPQGPPEA-QLQ 351
Query: 527 PTQAHQSVTPPQGLSPT--------VCTTHSSKATGSKDSTDATTEKAANDTSKASASTR 578
P Q PP+ SPT H S + S+ + + + ++ +S S+
Sbjct: 352 PAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSST 411
Query: 579 PGSLLPAP 586
P PAP
Sbjct: 412 PAKTQPAP 419
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 45.1 bits (105), Expect = 3e-04
Identities = 92/403 (22%), Positives = 140/403 (34%), Gaps = 60/403 (14%)
Query: 472 VAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPL----ILPQAP-SGPSYAIYLQ 526
+AP + PV T P + P+ PSP ++ PL + P+ P S PS ++
Sbjct: 683 LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA 742
Query: 527 PTQ---------AHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASAST 577
T +H S P SP C T S A+ + S+ T A+ S S
Sbjct: 743 GTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATA-SSKGTLTYLADSPSPLGVSV 801
Query: 578 RPGSLLPAPERQGAKSRTREPAGERGSK----RASMLEDSGSKKKFKEDL---------- 623
P + P ++ A T P G S AS L ++ + +D
Sbjct: 802 SPQTKRPPTKKGSAGPDT--PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP 859
Query: 624 --KGLENVSAT--LFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIP 679
KG SA L P G +P + + ++ KE + +P +P +
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK----QAPALSMTS 915
Query: 680 VTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQ 739
+ + A P +PT AA P SP + P P P+
Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPPAATP--PSPKGGPATPSPKWAPTPPAATPPSP 973
Query: 740 HLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQS 799
G +P+ + + +P + P SP+ +P+ A T P P G
Sbjct: 974 KGGPATPSPKGAPTPPAA-TPPSPKGGPATPSPKGAPT---------PPAVTPPSPKGSP 1023
Query: 800 VAV---TGAQQP---VPVTPKGSQLVAESFFRTPGGPTKPTSS 836
A GA P P +PKGS G PT P ++
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATP---LPKGAPTTPAAT 1063
Score = 37.4 bits (85), Expect = 0.061
Identities = 91/426 (21%), Positives = 147/426 (34%), Gaps = 77/426 (18%)
Query: 415 PSSPIKTNKAESSQNSA-PFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVA 473
P SP S+ N A PFPS + I LE +S + L + P A
Sbjct: 48 PCSPAPQQCPLSAANQASPFPSP----STIASTPLEVPFPQSSSGTALPLGTA----PEA 99
Query: 474 PLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQ-PTQAHQ 532
P P+LI P P+ P+ L+ A P+I P PS + L A
Sbjct: 100 PT----------FLPNLIGP----PISPAALALASPMIAPTLKGTPSSSAPLALVALAPH 145
Query: 533 SVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAK 592
SV P + T+ S A S + A K + + P ++P P+
Sbjct: 146 SVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPK----- 200
Query: 593 SRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAES 652
T P + + S + G+ ++ T + I Q S
Sbjct: 201 -GTPSPPCIVSTVPYHCVTPMASIQ------SGVASLPQTTPTTTLAIASPQVKDTTISS 253
Query: 653 ILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPV 712
+L +N +LS P++ P + L+ + P VT + P + P+
Sbjct: 254 VLISPQNPGSLS-----LKGPVS---PPAALSLSTQSLPV--VTSSQKTAGPNTPPDFPI 303
Query: 713 GNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAP 772
SH P+ S ++Q LG P+ LS P +++++V
Sbjct: 304 S-----LGSHLAPLHQSSFG----SVQLLGQTGPSA-LS----------DPTVKTISVDH 343
Query: 773 ENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQP-----------VPVTPKGSQLVAE 821
+ G + P+P +++ +VA P + +P GS VA
Sbjct: 344 SSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVAT 403
Query: 822 SFFRTP 827
SF +P
Sbjct: 404 SFSLSP 409
Score = 36.6 bits (83), Expect = 0.10
Identities = 37/135 (27%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Query: 703 SPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVS 762
+PT+ AA P SP + P P P+ GL +P + + +P + P S
Sbjct: 1240 APTTPAATPP--SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV-VTPPS 1296
Query: 763 PRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSV--AVTGAQQPVPVTPKGSQLVA 820
P+ P+ A T PG P G AVT P +PKG+ +
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT------PPSPKGTPTLP 1350
Query: 821 ESFFRTPGGPTKPTS 835
+ + GGPT P+S
Sbjct: 1351 ATTPSSKGGPTTPSS 1365
Score = 35.8 bits (81), Expect = 0.18
Identities = 64/267 (23%), Positives = 108/267 (40%), Gaps = 33/267 (12%)
Query: 347 GPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIES 406
GP+ + +S +SP I PS AKN ++G P T P+ + V+ S
Sbjct: 1703 GPQ-TKKSSATSPPICPDPS------------AKN--GSKG-PLSTVAPAPLLPVQKDSS 1746
Query: 407 DRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARS 466
K A SP S+ S P + + + K + S+ V + LA S
Sbjct: 1747 KTAKGKDASHSPKGPLAPPESKASTPLTAAAFE-KVLPKPESASVSAAPSPPVSLPLAPS 1805
Query: 467 GPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSG--PSYAIY 524
PV L P + ++P L+ PL P+ +PLI P+ SG P ++
Sbjct: 1806 ----PVPTLPP--KQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859
Query: 525 LQ---PTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGS 581
+ P A V P P T ++K +G++ +D + + S A+T+
Sbjct: 1860 VNMPTPKSAGIPVPTPSAKQP---VTKNNKGSGTESDSDESVPELEEQDS-TQATTQQAQ 1915
Query: 582 LLPAPE-RQGAKSRTREPAGERGSKRA 607
L A E + S+ ++ E+ +++A
Sbjct: 1916 LAAAAEIDEEPVSKAKQSRSEKKARKA 1942
Score = 30.0 bits (66), Expect = 9.7
Identities = 75/324 (23%), Positives = 116/324 (35%), Gaps = 63/324 (19%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLE---VRRSSKENCAKNLF--STRGKPNFTR-HPSLIK 399
T P ++P + +P + T + SSKE S +G P T P
Sbjct: 1334 TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Query: 400 LVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLA-AICKMQLEEQSSESRQK 458
+ S + D P SP K ++ A PSK A+ + L++ + S K
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 459 --VKVQLARSGPCKPV----APLDPPVNAEMELT-----APSLIQPLGMVPLIPSPLSSA 507
++ P P +P +PP ++ + AP+ P+G P +P+ + S+
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG-APTLPAVIPSS 1512
Query: 508 VPLILPQAPSG------PSYAIYLQPTQAHQSVTPPQGLSPTVCT--------------- 546
P +P PS P+ + + T A ++ P + L P T
Sbjct: 1513 -PKEVPATPSSRRDPIAPTATLLSKKTPA--TLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
Query: 547 ---THSSKATGSKDSTDATTEKAA------------NDTSKASASTRPGSLLPAPERQGA 591
T SSK S + +T K A S A T P P+PE+ A
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Query: 592 KSRTREPAGERGSK--RASMLEDS 613
T P G S S L+DS
Sbjct: 1630 ---TPAPKGTPTSPPVTPSSLKDS 1650
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 43.9 bits (102), Expect = 6e-04
Identities = 96/431 (22%), Positives = 165/431 (38%), Gaps = 57/431 (13%)
Query: 416 SSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQL-------ARSGP 468
S+P+ + + S P + + CKM E++S R KV A P
Sbjct: 981 SAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPP 1040
Query: 469 CKPVAPLDP--PVNAEME--LTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIY 524
P AP P P+N++ + L P L+ PL +P I + +AP P +
Sbjct: 1041 TVPEAPAPPQKPLNSQSQKHLAPPPLLSPL--LPSIKPTVRKTRQDGSQEAPEAP-LSSE 1097
Query: 525 LQPTQAHQSVTPPQG--LSPTVCTT-----HSSKATGSKDSTDATTEKAANDTSKASAST 577
L+P + + ++P T+ H S +T + T++ + T+++S T
Sbjct: 1098 LEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKT 1157
Query: 578 RPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDL--KGLENVSATLFP 635
+ APE Q + S T +P + + + S S K E + LE +T
Sbjct: 1158 PEPVVPTAPELQPSTS-TDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTD 1216
Query: 636 SGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHV 695
P+T S +++ K SS +P + ++P + P TS++ + P++
Sbjct: 1217 R----PVT--SEPTSQATRGRKNRSSVKTPEPVVPTAP--ELQPSTSTDQPVTSEPTYQA 1268
Query: 696 TPLKLMVSPTSVAAVPVGNSPALASS-------HPVPIQNPSSAIVNF----TLQHLGLI 744
T + S V +P L S P P + + N T + +
Sbjct: 1269 TRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPT 1328
Query: 745 SPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVP--GQSQPNGQSVAV 802
+P +Q+S S PV+P+ S + T N +S VP + P+
Sbjct: 1329 APELQISTSTDQ---PVTPKPTS---RTTRSRTNMSSVKNPESTVPIAPELPPS------ 1376
Query: 803 TGAQQPVPVTP 813
T +QPV P
Sbjct: 1377 TSTEQPVTPEP 1387
Score = 39.7 bits (91), Expect = 0.012
Identities = 111/538 (20%), Positives = 178/538 (33%), Gaps = 81/538 (15%)
Query: 346 TGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIE 405
T PE+ P+TS PV S + R S+ + K T P+ ++L S
Sbjct: 1164 TAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSV---------KTPETVVPTALELQPSTS 1214
Query: 406 SDRRKINSAPSSPIKTNKAESSQNSAPFP--SKMAQLAAICKMQLEEQSSESRQKVKVQL 463
+D R + S P+S + S P P +L S + Q + +
Sbjct: 1215 TD-RPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRK 1273
Query: 464 ARSG--PCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSY 521
RS +PV P P + P +P + +SS V P+ P
Sbjct: 1274 NRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSS-VKTPETVVPTAPEL 1332
Query: 522 AIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDAT------------------- 562
I T Q VTP PT TT S S + ++T
Sbjct: 1333 QI---STSTDQPVTP----KPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTP 1385
Query: 563 --TEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFK 620
T +A S+ P +L+P + + T +P + +A+ + S K
Sbjct: 1386 EPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTP 1445
Query: 621 EDL----KGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAG 676
E + L+ ++T P + P + + S + + P + +
Sbjct: 1446 ETVVPTAPELQPSTSTDQP---VTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASAST 1502
Query: 677 VIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNF 736
PVTS + + + +K +P +V P+ ++ PV + S A
Sbjct: 1503 DQPVTSEPTSRTTRGRKNRSSVK---TPETVVPAAPELQPSTSTDQPVTPEPTSRATRGR 1559
Query: 737 TLQHLGLISPNVQLSASPGSGIVPVSPRIESVN-----VAPENAGTQQGRATNYDS---- 787
T + S IVP++P ++ V PE TN S
Sbjct: 1560 TNRS----------SVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTP 1609
Query: 788 --PVPGQSQPNGQSVAVTGAQQPVPVTPK-GSQLVAESFFRTPGGPTKPTSSSCMDFE 842
VP +P+ T Q PVTPK S+ R+ KP + D E
Sbjct: 1610 EPVVPTAPEPH----PTTSTDQ--PVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLE 1661
Score = 30.4 bits (67), Expect = 7.4
Identities = 37/149 (24%), Positives = 60/149 (40%), Gaps = 22/149 (14%)
Query: 526 QPTQAHQSVTPPQGLSPTVCTTHSSKATGS---------------KDSTDATTEKAANDT 570
+PTQA +TPPQ L P+ C S + TG+ ++S D+ T+
Sbjct: 717 EPTQAFM-LTPPQELGPSHC---SFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHL 772
Query: 571 SKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVS 630
P +P + + T EP G +G R ++ + G K+ E + G E
Sbjct: 773 EAYGPCLSPPRAIPGDQHPESPVHT-EPMGIQGRGRQTVDKVMGIPKETAERV-GPER-G 829
Query: 631 ATLFPSGYLIPLTQCSSLGAESILSGKEN 659
+ L+P Q G E + GK++
Sbjct: 830 PLERETEKLLPERQTDVTGEEELTKGKQD 858
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 43.9 bits (102), Expect = 6e-04
Identities = 75/309 (24%), Positives = 109/309 (35%), Gaps = 37/309 (11%)
Query: 474 PLDPPVNAEMELTA-----PSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPT 528
P+ PP NA L A P L PL + P PSP + LP P+ P P+
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAP--PSPSAPPSLQTLPSPPATP-------PS 366
Query: 529 QAHQSV-TPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGS-LLPAP 586
QA S+ TPP P++ T + S S + S A+T GS L A
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 587 ERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCS 646
S + A R + + L + +L P+ + PL+
Sbjct: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA--VSPLSSPL 484
Query: 647 SLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTS 706
++ LS + S +P + P+ T S L P L P S
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLE-----TQSSL----------APPSLQTPPAS 529
Query: 707 VAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIE 766
+ P+ N P+LA P P+Q S+ + L+ +P L A P P
Sbjct: 530 LTTPPLENLPSLA---PPPLQTASAPLTTPHLETPPCPAP-CPLQAPPSPLTTPPPETPS 585
Query: 767 SVNVAPENA 775
S+ P A
Sbjct: 586 SIATPPPQA 594
Score = 38.5 bits (88), Expect = 0.027
Identities = 94/379 (24%), Positives = 136/379 (35%), Gaps = 59/379 (15%)
Query: 471 PVAPLDPPVNAEMELTAPSLIQP--LGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPT 528
P P PP A +T P + P L +P I P S P + QAP P + L
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL--QAPPSP---LALSSL 412
Query: 529 QAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLP-APE 587
QA S+ SPT+ THS T S T A+ ++ +RP S P +P
Sbjct: 413 QATTSLG-----SPTLQATHSF-LTMSPRQTQAS----------LTSPSRPASTPPDSPP 456
Query: 588 RQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSS 647
Q S P + + L + S + L+ +S+ S P SS
Sbjct: 457 LQAPLSLPASPPLQ------TSLSPAVSPLSSPLTIHPLQALSSLASHS----PQAPLSS 506
Query: 648 LGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSP--T 705
L I+ E S+L+P P P + + N PS PL+ +P T
Sbjct: 507 L----IMPPLETQSSLAP-------PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 706 SVAAVPVGNSPALASSHPVPI-----QNPSSAIVNFTLQHLGLISPNVQ-LSASPGSGIV 759
P +P + P P+ + PSS L SP +Q L + P S +
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615
Query: 760 PVSPRIESVNVAPENAGTQQGRATNYDSPV--PGQSQPNGQSVAVTGAQQPVPVTPKGSQ 817
P+ P A+ SP+ P PN +V + A P +P S
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA----PFSPPPSP 671
Query: 818 LVAESFFRTPGGPTKPTSS 836
V F P P+++
Sbjct: 672 PVQAPFSPPASPPVSPSAT 690
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 43.9 bits (102), Expect = 6e-04
Identities = 72/323 (22%), Positives = 125/323 (38%), Gaps = 32/323 (9%)
Query: 353 NTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKIN 412
N +GS P+ L R + NL S R + + + DR +
Sbjct: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP--LSAYERVSGRTSPPLLDRARSR 2408
Query: 413 SAPSSPIKTNKAESSQNSAPFPS-KMAQLAAICKMQLEEQSSESRQKVKVQLARSGPC-- 469
+ PS+P +++ + AP PS +M Q A + L + R V + C
Sbjct: 2409 TPPSAP---SQSRMTSERAPSPSSRMGQ--APSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
Query: 470 ---KPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSG---PSYAI 523
PVA + + T S GM+ +P+P + P A +G PS
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS-VPAPGVPHSDVGEPPASTGAQQPSALA 2522
Query: 524 YLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLL 583
LQP + +S SS ++ S S+ +++ +++ +S +S+S GS L
Sbjct: 2523 ALQPAKERRS--------------SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
Query: 584 PA-PERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPL 642
P PE + + PA + + E + +K+K + + S++ S
Sbjct: 2569 PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS 2628
Query: 643 TQCSSLGAESILSGKENSSALSP 665
+ SS + S S +SS+ SP
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSP 2651
Score = 35.0 bits (79), Expect = 0.30
Identities = 40/183 (21%), Positives = 77/183 (42%), Gaps = 24/183 (13%)
Query: 491 IQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSS 550
+QP + +PSP + + P P+ A + + + S + ++ SS
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS---------SSSSSSSS 2620
Query: 551 KATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPER-QGAKSRTREPAGERGSKRASM 609
++ S S+ +++ +++ +S +S+S+ P P P+ S + P GER S+
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR---- 2676
Query: 610 LEDSGSKKKFKEDLKGLENVSATLF----PSGYLIPLTQCSSLGAESILSGKENSSALSP 665
S +K + L+ ++S + PS P Q SS G+ S SP
Sbjct: 2677 -----SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR-SP 2730
Query: 666 NHR 668
+H+
Sbjct: 2731 SHK 2733
Score = 32.7 bits (73), Expect = 1.5
Identities = 109/511 (21%), Positives = 179/511 (35%), Gaps = 65/511 (12%)
Query: 337 RGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRG-KPNFTRHP 395
R R PA + +P G S TP+ R S+ + +R + +R
Sbjct: 648 RSRTPARRGRSRSRTPARRGRSR--SRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR 705
Query: 396 SLIKLVKSIESDRRKINSAPSSPIKTNKAESSQ-----NSAPFPSKMAQLAAICKMQLEE 450
SL++ +S ++ + SS + NK+ +SQ NS+P K +++++ L
Sbjct: 706 SLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP-EMKKSRISSRRSRSLSS 764
Query: 451 QSSESRQKVKVQ--LARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAV 508
S+++ ++ ++ L+ S PC PP + + P + P S SS+
Sbjct: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP---KAKSRTPPRRSRSSSSP 821
Query: 509 PLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAAN 568
P P Q+H S +P H +G+ + T AN
Sbjct: 822 P---------PKQKSKTPSRQSHSSSSP-----------HPKVKSGTPPRQGSITSPQAN 861
Query: 569 DTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLEN 628
+ S P PE KSRT GS + + ++
Sbjct: 862 EQSVTPQRRSCFESSPDPE---LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPK 918
Query: 629 VSATLFP-----SGYLIP-----LTQCSSLGAESILSGKENSSALSP--NHRIYSSPIAG 676
V A + P SG P ++ + + S+ S L P +H SSP
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK 978
Query: 677 VIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNF 736
V P T + S ++P P A P G S + S P P + ++V
Sbjct: 979 VKPETPPRQS----HSGSISPY-----PKVKAQTPPGPSLS-GSKSPCPQEKSKDSLVQS 1028
Query: 737 TLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPN 796
L L + V+ S PG VS S+ + ++ T ++ SP QS
Sbjct: 1029 CPGSLSLCA-GVKSSTPPGESYFGVS----SLQLKGQSQ-TSPDHRSDTSSPEVRQSHSE 1082
Query: 797 GQSVAVTGAQQPVPVTPKGSQLVAESFFRTP 827
S+ P + S V E R+P
Sbjct: 1083 SPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
Score = 31.2 bits (69), Expect = 4.3
Identities = 60/287 (20%), Positives = 100/287 (34%), Gaps = 32/287 (11%)
Query: 555 SKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSG 614
S+ T T + + + R S P R+ ++SRT +R R+ +
Sbjct: 1994 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRR 2053
Query: 615 SKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPI 674
S+ + +G S T P + + S+ G+ S + SA P R +S
Sbjct: 2054 SRSRTPRTARGKR--SLTRSPPA----IRRRSASGSSS----DRSRSATPPATRNHSGSR 2103
Query: 675 AGVIPVTSSELTAVNFPSFHVTPLKL-----MVSPTSVAAVPV------GNSPALASSHP 723
+ + SS ++ + PS TPL M+ P + P+ G S
Sbjct: 2104 TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPR 2163
Query: 724 VPIQNPSSAIVNFTLQHLGLISPNVQLSAS---PGSGIVPVSPRIESVNVAPENAGTQQG 780
+P +S N + L + L + P ++ R+ V +
Sbjct: 2164 IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTA 2223
Query: 781 RATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTP 827
A N S +P S + A+ A P P L A+S RTP
Sbjct: 2224 PAANLASRIPAAS-----AAAMNLASARTPAIPTAVNL-ADS--RTP 2262
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 43.5 bits (101), Expect = 8e-04
Identities = 84/330 (25%), Positives = 118/330 (35%), Gaps = 45/330 (13%)
Query: 501 PSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTD 560
PS A P Q S P QP + Q PP SP + S S
Sbjct: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 561 ATTEKAANDTSKASASTRPG-------SLLPAPE----RQGAKSRTREPAGERGSK---- 605
++ A + +P + P P+ +Q A S+ R P + S+
Sbjct: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
Query: 606 -RASMLEDSGSKKKFKEDLKGLENVSATLFPSGY--LIPLTQCSSLGAESILSGKENSSA 662
+AS S K +ED+ N+S PS L +G E LS ++S
Sbjct: 610 SQASSAPSMTSSKGGQEDM----NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSG 665
Query: 663 LSPNHRIYSSPIAGVI-PVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGN-SPALAS 720
+S + S+P P TS L + PS +P+ SP SVA G SPA
Sbjct: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVG---SPASVAQSRSGPLSPAAVP 720
Query: 721 SHPVPIQNPS---------SAIVNFTLQHLGLISPNVQL----SASPGSGIVPVSPRIES 767
+ +P + PS S + Q G + N Q+ S PGS + SPR S
Sbjct: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSAL---SPRQPS 777
Query: 768 VNVAPENAGTQQGRATNYDSPVPGQSQPNG 797
G+ Q + P GQ P G
Sbjct: 778 GGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 43.5 bits (101), Expect = 8e-04
Identities = 84/330 (25%), Positives = 118/330 (35%), Gaps = 45/330 (13%)
Query: 501 PSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTD 560
PS A P Q S P QP + Q PP SP + S S
Sbjct: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 561 ATTEKAANDTSKASASTRPG-------SLLPAPE----RQGAKSRTREPAGERGSK---- 605
++ A + +P + P P+ +Q A S+ R P + S+
Sbjct: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
Query: 606 -RASMLEDSGSKKKFKEDLKGLENVSATLFPSGY--LIPLTQCSSLGAESILSGKENSSA 662
+AS S K +ED+ N+S PS L +G E LS ++S
Sbjct: 610 SQASSAPSMTSSKGGQEDM----NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSG 665
Query: 663 LSPNHRIYSSPIAGVI-PVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGN-SPALAS 720
+S + S+P P TS L + PS +P+ SP SVA G SPA
Sbjct: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS--PSPVG---SPASVAQSRSGPLSPAAVP 720
Query: 721 SHPVPIQNPS---------SAIVNFTLQHLGLISPNVQL----SASPGSGIVPVSPRIES 767
+ +P + PS S + Q G + N Q+ S PGS + SPR S
Sbjct: 721 GNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSAL---SPRQPS 777
Query: 768 VNVAPENAGTQQGRATNYDSPVPGQSQPNG 797
G+ Q + P GQ P G
Sbjct: 778 GGQIHTGMGSYQQNSMGSYGPQGGQYGPQG 807
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 43.5 bits (101), Expect = 8e-04
Identities = 110/533 (20%), Positives = 183/533 (34%), Gaps = 90/533 (16%)
Query: 346 TGPEISPNTSGSSPV-----IHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKL 400
T P I+P TSG+S + TP+ L SS + ST T +P+ +
Sbjct: 1498 TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST---TTITPNPTSTRT 1554
Query: 401 VKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVK 460
+ +S P P T+ + S+PF S A K
Sbjct: 1555 RTPVAHTNSATSSRPPPPFTTHSPPT--GSSPFSSTGPMTATSFK--------------- 1597
Query: 461 VQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPS 520
P + + T P+ + P + PS + P A S
Sbjct: 1598 ------------TTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITP---THAQMATS 1642
Query: 521 YAIYLQPTQAHQSVTPPQGL----------SPTVCTTHSSKATGSKDSTDATTEKAANDT 570
+I+ PT ++ PP L + T+ T+ +S+A S ++ +T ++ +
Sbjct: 1643 ASIHSMPT---GTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTS 1699
Query: 571 SKASA---STRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLE 627
S A ST ++ P P G T +G S S S K L
Sbjct: 1700 STHHAEATSTSTTNITPNPTSTGTPPMTVTTSG------TSQSRSSFSTAKTSTSLH--S 1751
Query: 628 NVSATLFPSGYLIPLTQCSSLGAESILSGKEN--------SSALSPNHRIYSSPIAGVIP 679
+ S+T P + T +S+ +G +S+ P SP G P
Sbjct: 1752 HTSSTHHPE---VTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTP 1808
Query: 680 VTSS-ELTAVNFPSFHVTPLKLMVSPTSVAAVP-VGNSPALASSHPVPIQNPSSAIVNFT 737
++S+ +TA +F + P T VP S S+H V I + + +
Sbjct: 1809 ISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSAS 1868
Query: 738 LQHL--GLISPNVQLSASPGSGIV-PVSPRIESVNVAPENAGTQQ--------GRATNYD 786
+ + G I P + A+ + P++P + +P + T + +T++
Sbjct: 1869 IHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHP 1928
Query: 787 SPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPT--KPTSSS 837
P + TG + PV T S + F T PT P SS+
Sbjct: 1929 EVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST 1981
Score = 42.0 bits (97), Expect = 0.002
Identities = 77/379 (20%), Positives = 123/379 (32%), Gaps = 41/379 (10%)
Query: 468 PCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQP 527
P +P A E T P P SP+ S P+ + +Y P
Sbjct: 1380 PTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTY-----P 1434
Query: 528 TQAHQSVTPPQGLSP-----------TVCT-THSSKATGSKDSTDATTEKAANDTSKASA 575
T +H T P + P TV T TH+ AT + + + T T KA+
Sbjct: 1435 TPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATG 1494
Query: 576 STRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFP 635
ST AP S T + + + S + ++ + T P
Sbjct: 1495 STH-----TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549
Query: 636 SGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSEL---TAVNFPS 692
+ T+ S S + + + SSP + P+T++ T PS
Sbjct: 1550 TS---TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPS 1606
Query: 693 FHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSA 752
T L V P S + V + +H Q +SA ++ G I P L A
Sbjct: 1607 HPQTTLPTHVPPFSTSLVTPSTHTVITPTH---AQMATSASIH--SMPTGTIPPPTTLKA 1661
Query: 753 SPGSGIVP--------VSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTG 804
+ + P S + S+N A + ++ + + S N +
Sbjct: 1662 TGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST 1721
Query: 805 AQQPVPVTPKGSQLVAESF 823
P+ VT G+ SF
Sbjct: 1722 GTPPMTVTTSGTSQSRSSF 1740
Score = 31.6 bits (70), Expect = 3.3
Identities = 76/358 (21%), Positives = 119/358 (33%), Gaps = 66/358 (18%)
Query: 418 PIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDP 477
P+ + +SQ + F + A + I Q+S SR P P+ P
Sbjct: 2063 PMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRP----------PSSPITTQLP 2112
Query: 478 PVNAEME--LTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVT 535
+++ T L P PS +SS VP +H S
Sbjct: 2113 HLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVP-------------------SSHSS-- 2151
Query: 536 PPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRT 595
PQ SP+V T+ S + +T ++ ++ T +AS L P+ R
Sbjct: 2152 -PQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRA 2210
Query: 596 REPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILS 655
P S L + L + S FPS P T S+ A + S
Sbjct: 2211 TLPHTISSPFTLSALLPISTVTVSPTPSSHLAS-STIAFPS---TPRTTASTHTAPAFSS 2266
Query: 656 GKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNS 715
S + S R+ P +G + +TS V +P
Sbjct: 2267 QSTTSRSTSLTTRV---PTSGFVSLTS-----------------------GVTGIPTSPV 2300
Query: 716 PALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPE 773
L + HP P +P++ + +L G + +S S G+ P SP + SV E
Sbjct: 2301 TNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVS-SLGTP-TPTSPGVCSVREQQE 2356
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,096,502
Number of Sequences: 37866
Number of extensions: 1889069
Number of successful extensions: 8056
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 6782
Number of HSP's gapped (non-prelim): 1364
length of query: 867
length of database: 18,247,518
effective HSP length: 111
effective length of query: 756
effective length of database: 14,044,392
effective search space: 10617560352
effective search space used: 10617560352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.