Guide to the Human Genome
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Search of human proteins with 124249376

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|124249376 proline rich 21 [Homo sapiens]
         (389 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|124249376 proline rich 21 [Homo sapiens]                           839   0.0  
gi|239748030 PREDICTED: hypothetical protein XP_002346496 [Homo ...   378   e-105
gi|239750721 PREDICTED: hypothetical protein, partial [Homo sapi...    79   7e-15
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ...    79   7e-15
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               74   3e-13
gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo ...    72   9e-13
gi|239753972 PREDICTED: hypothetical protein [Homo sapiens]            69   6e-12
gi|116284392 mucin 2 precursor [Homo sapiens]                          67   4e-11
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    64   3e-10
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    64   3e-10
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            63   5e-10
gi|239755199 PREDICTED: hypothetical protein [Homo sapiens]            59   7e-09
gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo ...    58   1e-08
gi|193788649 retinoic acid induced 2 [Homo sapiens]                    57   3e-08
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             57   4e-08
gi|239755446 PREDICTED: hypothetical protein [Homo sapiens]            57   4e-08
gi|239749927 PREDICTED: hypothetical protein [Homo sapiens]            57   4e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   8e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    55   8e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    54   3e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   4e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          53   4e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          53   4e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          53   4e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    53   5e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  52   7e-07
gi|55750041 atrophin-1 [Homo sapiens]                                  52   7e-07
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               50   3e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             50   5e-06
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    49   8e-06

>gi|124249376 proline rich 21 [Homo sapiens]
          Length = 389

 Score =  839 bits (2167), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS 60
           MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS
Sbjct: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS 60

Query: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120
           STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL
Sbjct: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120

Query: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRP 180
           HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRP
Sbjct: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRP 180

Query: 181 FVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHA 240
           FVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHA
Sbjct: 181 FVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHA 240

Query: 241 SSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPT 300
           SSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPT
Sbjct: 241 SSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPT 300

Query: 301 ALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKSLHLRLFSHSSCLVGFSQ 360
           ALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKSLHLRLFSHSSCLVGFSQ
Sbjct: 301 ALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKSLHLRLFSHSSCLVGFSQ 360

Query: 361 QGNVLLLSARATFNTCLLVSNMYFLIISY 389
           QGNVLLLSARATFNTCLLVSNMYFLIISY
Sbjct: 361 QGNVLLLSARATFNTCLLVSNMYFLIISY 389


>gi|239748030 PREDICTED: hypothetical protein XP_002346496 [Homo
           sapiens]
          Length = 221

 Score =  378 bits (970), Expect = e-105
 Identities = 184/221 (83%), Positives = 190/221 (85%), Gaps = 1/221 (0%)

Query: 169 HGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPS 228
           H  SS  LHPRPF+H  S T     LF HG SS  LHP PF+H SSP AL P LFTHGPS
Sbjct: 2   HACSSTALHPRPFIHGFSFTTFLQQLFPHG-SSTALHPWPFIHGSSPMALHPRLFTHGPS 60

Query: 229 SMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPL 288
           S  LHP PF H SSP +L P LFTH PSSMPLHPRPF+HASSPTALRPCLFTHGPSSMPL
Sbjct: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120

Query: 289 HPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKSLHLRL 348
           HPRPFVHASSPTAL PCLFTHGPSSMPLHPRPF+HASSSTSLHPRPFIHASSSKSLHLRL
Sbjct: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSSTSLHPRPFIHASSSKSLHLRL 180

Query: 349 FSHSSCLVGFSQQGNVLLLSARATFNTCLLVSNMYFLIISY 389
           FSHSSCLVGFSQQGNVLLLSARATFNTCLLV+NMYFLIISY
Sbjct: 181 FSHSSCLVGFSQQGNVLLLSARATFNTCLLVANMYFLIISY 221



 Score =  370 bits (951), Expect = e-103
 Identities = 173/197 (87%), Positives = 177/197 (89%), Gaps = 14/197 (7%)

Query: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS 60
           MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS
Sbjct: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS 60

Query: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120
           STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL
Sbjct: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120

Query: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRP 180
           HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASS T+              LHPRP
Sbjct: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSSTS--------------LHPRP 166

Query: 181 FVHASSPTALRPCLFTH 197
           F+HASS  +L   LF+H
Sbjct: 167 FIHASSSKSLHLRLFSH 183



 Score =  290 bits (742), Expect = 2e-78
 Identities = 140/182 (76%), Positives = 147/182 (80%), Gaps = 1/182 (0%)

Query: 32  SSTALHPWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMP 91
           SSTALHP PFIHG S      +LF HG SSTALHP PF HGSSPM+LHPRLFTH PSS  
Sbjct: 5   SSTALHPRPFIHGFSFTTFLQQLFPHG-SSTALHPWPFIHGSSPMALHPRLFTHGPSSTA 63

Query: 92  LHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPR 151
           LHP PF H SSP +L P LFTH PSSMPLHPRPFVHASSPTAL PCLFTHGPSSMPLHPR
Sbjct: 64  LHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPR 123

Query: 152 PFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVH 211
           PF+HASSPTALPPCLFTHGPSSMPLHPRPF+HASS T+L P  F H  SS  LH R F H
Sbjct: 124 PFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSSTSLHPRPFIHASSSKSLHLRLFSH 183

Query: 212 AS 213
           +S
Sbjct: 184 SS 185



 Score =  281 bits (719), Expect = 7e-76
 Identities = 137/185 (74%), Positives = 144/185 (77%), Gaps = 1/185 (0%)

Query: 85  HSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPS 144
           H+ SS  LHPRPF+H  S T     LF HG SS  LHP PF+H SSP AL P LFTHGPS
Sbjct: 2   HACSSTALHPRPFIHGFSFTTFLQQLFPHG-SSTALHPWPFIHGSSPMALHPRLFTHGPS 60

Query: 145 SMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 204
           S  LHP PF H SSP +L P LFTH PSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL
Sbjct: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120

Query: 205 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRP 264
           HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPF+HASS T+L P  F H  SS  LH R 
Sbjct: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSSTSLHPRPFIHASSSKSLHLRL 180

Query: 265 FLHAS 269
           F H+S
Sbjct: 181 FSHSS 185



 Score =  248 bits (634), Expect = 5e-66
 Identities = 125/183 (68%), Positives = 133/183 (72%), Gaps = 15/183 (8%)

Query: 57  HGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPS 116
           H  SSTALHP PF HG S  +   +LF H  SS  LHP PF+H SSP AL P LFTHGPS
Sbjct: 2   HACSSTALHPRPFIHGFSFTTFLQQLFPHG-SSTALHPWPFIHGSSPMALHPRLFTHGPS 60

Query: 117 SMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPL 176
           S  LHP PF H SSP +L P LFTH PSSMPLHPRPF+HASSPTAL PCLFTHGPSSMPL
Sbjct: 61  STALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 120

Query: 177 HPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF--------------VHASSPTALPPCL 222
           HPRPFVHASSPTAL PCLFTHGPSSMPLHPRPF              +HASS  +L   L
Sbjct: 121 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSSTSLHPRPFIHASSSKSLHLRL 180

Query: 223 FTH 225
           F+H
Sbjct: 181 FSH 183



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 18/32 (56%), Positives = 22/32 (68%)

Query: 322 VHASSSTSLHPRPFIHASSSKSLHLRLFSHSS 353
           +HA SST+LHPRPFIH  S  +   +LF H S
Sbjct: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGS 32


>gi|239750721 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 230

 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 72/256 (28%), Positives = 113/256 (44%), Gaps = 39/256 (15%)

Query: 110 LFTHGPSSMPLHPR--PFVHASSPTALPPCLFTHGPSSMPLHP--RPFLHASSPTALPPC 165
           L  H    + +HP   PF+H        PC+  H P    +HP   P +H S   ++ PC
Sbjct: 1   LSIHPSIHLSIHPSIYPFIH--------PCI--HPPICSSIHPSIHPSIHPSIHLSIHPC 50

Query: 166 LFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPC-- 221
           +  H P    +HP   +H S+   +   +     +S+ LHP   P +H S  T +     
Sbjct: 51  I--HPPICSSIHPS--IHPSTYLFIHLSMHPSIHASIHLHPSIHPSIHPSIHTYMHTSTY 106

Query: 222 LFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTH 281
           LF H    + +HP   +H S   ++ P + +   +S+ L   P  HAS    + P +  H
Sbjct: 107 LFIH----LSMHPSIHIHPSICPSIHPSIHSSIHASIHLSVHPSFHASIHPCIHPSM--H 160

Query: 282 GPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHPR--PFVHASSSTSLHPRPFIH 337
             + + +HP   P +HAS    +   +F      + +HP   P +HAS   S+HP   IH
Sbjct: 161 PSTYLFIHPSMHPSIHASIHPPICSSIFP-----LFIHPSLYPSIHASIHLSVHPS--IH 213

Query: 338 ASSSKSLHLRLFSHSS 353
            S   S+HL   S+ S
Sbjct: 214 PSIHPSIHLSFLSYPS 229



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 60/239 (25%), Positives = 99/239 (41%), Gaps = 59/239 (24%)

Query: 42  IHGSSPMALHPRLFT------HGPSSTALHPC--PFTHGSSPMSLHPRLFTHSPSSMPLH 93
           IH S  +++HP ++       H P  +++HP   P  H S  +S+HP +  H P    +H
Sbjct: 3   IHPSIHLSIHPSIYPFIHPCIHPPICSSIHPSIHPSIHPSIHLSIHPCI--HPPICSSIH 60

Query: 94  P--------------RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTAL--P 135
           P               P +HA                S+ LHP   P +H S  T +   
Sbjct: 61  PSIHPSTYLFIHLSMHPSIHA----------------SIHLHPSIHPSIHPSIHTYMHTS 104

Query: 136 PCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLF 195
             LF H    + +HP   +H S   ++ P + +   +S+ L   P  HAS    + P + 
Sbjct: 105 TYLFIH----LSMHPSIHIHPSICPSIHPSIHSSIHASIHLSVHPSFHASIHPCIHPSM- 159

Query: 196 THGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHPR--PFVHASSPTALRPCL 250
            H  + + +HP   P +HAS    +   +F      + +HP   P +HAS   ++ P +
Sbjct: 160 -HPSTYLFIHPSMHPSIHASIHPPICSSIF-----PLFIHPSLYPSIHASIHLSVHPSI 212



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 49/199 (24%), Positives = 80/199 (40%), Gaps = 40/199 (20%)

Query: 1   MHACSSTALHP------RPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRL 54
           +H      +HP       P IH  ++      + P     ++H  P IH S    +HP +
Sbjct: 43  IHLSIHPCIHPPICSSIHPSIHPSTYLFIHLSMHP-SIHASIHLHPSIHPS----IHPSI 97

Query: 55  FTHGPSST------ALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRP 108
            T+  +ST      ++HP    H S   S+HP + +   +S+ L   P  HAS    + P
Sbjct: 98  HTYMHTSTYLFIHLSMHPSIHIHPSICPSIHPSIHSSIHASIHLSVHPSFHASIHPCIHP 157

Query: 109 CLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCL 166
            +  H  + + +HP   P +HAS                  +HP P   +  P  + P L
Sbjct: 158 SM--HPSTYLFIHPSMHPSIHAS------------------IHP-PICSSIFPLFIHPSL 196

Query: 167 FTHGPSSMPLHPRPFVHAS 185
           +    +S+ L   P +H S
Sbjct: 197 YPSIHASIHLSVHPSIHPS 215



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 40/147 (27%), Positives = 61/147 (41%), Gaps = 34/147 (23%)

Query: 222 LFTHGPSSMPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHASSPTALRPC 277
           L  H    + +HP   PF+H        PC+  H P    +HP   P +H S   ++ PC
Sbjct: 1   LSIHPSIHLSIHPSIYPFIH--------PCI--HPPICSSIHPSIHPSIHPSIHLSIHPC 50

Query: 278 LFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIH 337
           +  H P    +HP   +H S+       LF H      L   P +HAS    +H  P IH
Sbjct: 51  I--HPPICSSIHPS--IHPST------YLFIH------LSMHPSIHAS----IHLHPSIH 90

Query: 338 ASSSKSLHLRLFSHSSCLVGFSQQGNV 364
            S   S+H  + + +   +  S   ++
Sbjct: 91  PSIHPSIHTYMHTSTYLFIHLSMHPSI 117



 Score = 29.6 bits (65), Expect = 4.9
 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 8/79 (10%)

Query: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPS 60
           +H C   ++HP  ++       F+          ++HP P      P+ +HP L+    +
Sbjct: 151 IHPCIHPSMHPSTYL-------FIHPSMHPSIHASIHP-PICSSIFPLFIHPSLYPSIHA 202

Query: 61  STALHPCPFTHGSSPMSLH 79
           S  L   P  H S   S+H
Sbjct: 203 SIHLSVHPSIHPSIHPSIH 221


>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
           sapiens]
          Length = 828

 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 72/252 (28%), Positives = 109/252 (43%), Gaps = 50/252 (19%)

Query: 36  LHPWPFIHGSSPMALHPRLFTHGPSSTALHPC--PFTHGSSPMSLHPRL--FTHSPSSMP 91
           +HP P    +   ++HP +  H P+  ++HP   P TH S  +  HP +   TH P   P
Sbjct: 21  IHP-PLHPPTHSPSIHPSI--HPPTHPSIHPSIHPPTHPS--IHTHPPIHPHTHPPIHPP 75

Query: 92  LHP--RPFVHASSPTALRPCLF------THGPSSMPLHPRPFVHASSPTALPPCLFTHGP 143
            HP   P +H S   +L P         TH P+   +HP   +H S+   + P +  H  
Sbjct: 76  THPSIHPLIHPSIHPSLHPPTHSSIHPSTHPPTHSSIHPS--IHPSTHPLIHPSI--HPS 131

Query: 144 SSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFT--HGPSS 201
           +   +HP    H S+   + P +  H P+  P+HP   +H  +     P + +  H P+ 
Sbjct: 132 THSSIHPPTHSHPSTHPLIHPSI--HPPTHSPIHPS--IHPPTHPPTHPSIHSSIHLPTH 187

Query: 202 MPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHP--RPFVHASSPTA-----LRPCLFT 252
             +HP    F+H S           H P+  P+HP   PF+H S  +A     + P L T
Sbjct: 188 SSIHPPTHSFIHPS----------IHPPTHSPIHPLTHPFIHPSDSSAASAGGVGPALQT 237

Query: 253 HGPSSMPLHPRP 264
                M  HPRP
Sbjct: 238 R----MSGHPRP 245



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 63/232 (27%), Positives = 97/232 (41%), Gaps = 48/232 (20%)

Query: 131 PTALPPCLFTHGPSSMP-LHP--RPFLHASSPTALPPCLFTHGP----SSMPLHP--RPF 181
           P   PP   TH PS  P +HP   P +H S      P + TH P    +  P+HP   P 
Sbjct: 23  PPLHPP---THSPSIHPSIHPPTHPSIHPSIHPPTHPSIHTHPPIHPHTHPPIHPPTHPS 79

Query: 182 VHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHAS 241
           +H     ++ P L  H P+   +HP                 TH P+   +HP   +H S
Sbjct: 80  IHPLIHPSIHPSL--HPPTHSSIHPS----------------THPPTHSSIHPS--IHPS 119

Query: 242 SPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTA 301
           +   + P +  H  +   +HP    H S+   + P +  H P+  P+HP   +H  +   
Sbjct: 120 THPLIHPSI--HPSTHSSIHPPTHSHPSTHPLIHPSI--HPPTHSPIHPS--IHPPTHPP 173

Query: 302 LRPCLFT--HGPSSMPLHP------RPFVHASSSTSLHP--RPFIHASSSKS 343
             P + +  H P+   +HP       P +H  + + +HP   PFIH S S +
Sbjct: 174 THPSIHSSIHLPTHSSIHPPTHSFIHPSIHPPTHSPIHPLTHPFIHPSDSSA 225



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 72/247 (29%), Positives = 111/247 (44%), Gaps = 62/247 (25%)

Query: 1   MHACSSTALHPRPFIHGFSFTTFLQQLFPHGSSTALHP--WPFIHGSSPMALHPRLFTHG 58
           +H  +  ++H  P IH            PH +   +HP   P IH     ++HP L  H 
Sbjct: 50  IHPPTHPSIHTHPPIH------------PH-THPPIHPPTHPSIHPLIHPSIHPSL--HP 94

Query: 59  PSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSM 118
           P+ +++HP   TH  +  S+HP +    PS+ PL   P +H S+ +++ P   +H PS+ 
Sbjct: 95  PTHSSIHPS--THPPTHSSIHPSIH---PSTHPLI-HPSIHPSTHSSIHPPTHSH-PSTH 147

Query: 119 PLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHP 178
           PL   P +H  + + + P +  H P+  P HP   +H+S           H P+   +HP
Sbjct: 148 PLI-HPSIHPPTHSPIHPSI--HPPTHPPTHPS--IHSS----------IHLPTHSSIHP 192

Query: 179 --RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTA-----LPPCLFTHGPSS 229
               F+H S           H P+  P+HP   PF+H S  +A     + P L T     
Sbjct: 193 PTHSFIHPS----------IHPPTHSPIHPLTHPFIHPSDSSAASAGGVGPALQTR---- 238

Query: 230 MPLHPRP 236
           M  HPRP
Sbjct: 239 MSGHPRP 245



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 60/195 (30%), Positives = 87/195 (44%), Gaps = 34/195 (17%)

Query: 159 PTALPPCLFTHGPSSMP-LHP--RPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSP 215
           P   PP   TH PS  P +HP   P +H S      P + TH P    +HP      + P
Sbjct: 23  PPLHPP---THSPSIHPSIHPPTHPSIHPSIHPPTHPSIHTHPP----IHPH-----THP 70

Query: 216 TALPPCLFTHGPSSMPL-HP--RPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPT 272
              PP   TH PS  PL HP   P +H  + +++ P   TH P+   +HP   +H S+  
Sbjct: 71  PIHPP---TH-PSIHPLIHPSIHPSLHPPTHSSIHPS--THPPTHSSIHPS--IHPSTHP 122

Query: 273 ALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSL 330
            + P +  H  +   +HP    H S+   + P +  H P+  P+HP   P  H  +  S+
Sbjct: 123 LIHPSI--HPSTHSSIHPPTHSHPSTHPLIHPSI--HPPTHSPIHPSIHPPTHPPTHPSI 178

Query: 331 HPRPFIHASSSKSLH 345
           H    IH  +  S+H
Sbjct: 179 HSS--IHLPTHSSIH 191


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 72/251 (28%), Positives = 97/251 (38%), Gaps = 35/251 (13%)

Query: 87  PSSMPLHPRPFVHASSPTALRP-CLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSS 145
           P  +   P P ++   P    P  L    P  +PL P P      PT   P     GP  
Sbjct: 227 PPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMP------PTGPAPS----GPPG 276

Query: 146 MPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLH 205
            P  P P     +P   PP    H P+S    P P VH  +P    P    H P+S    
Sbjct: 277 PPQLPPP-----APGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHP 331

Query: 206 PRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPR-- 263
           P P VH  +P   PP    H P+     P P VH      + P      P++  +HP+  
Sbjct: 332 PAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAP 391

Query: 264 ------PFLHASSPTALRPCLFTHGPSSMPLHPR-PFVHASS---------PTALRPCLF 307
                 P +H  +P  + P      PS+  +HP+ P VH S+         P  LRP L 
Sbjct: 392 GVHPPAPGMHPQAP-GVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLP 450

Query: 308 THGPSSMPLHP 318
           + GP ++P  P
Sbjct: 451 SEGPGNIPPPP 461



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 65/223 (29%), Positives = 87/223 (39%), Gaps = 25/223 (11%)

Query: 114 GPSSMPLHPRPFVHASSPTA-LPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPS 172
           GP  +   P P ++   P   LP  L    P  +PL P P      PT   P     GP 
Sbjct: 226 GPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMP------PTGPAPS-GPPGPP 278

Query: 173 SMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPL 232
            +P  P P VH  +P         H P+S    P P VH  +P   PP    H P+S   
Sbjct: 279 QLP-PPAPGVHPPAPVV-------HPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH 330

Query: 233 HPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPR- 291
            P P VH  +P    P    H P+     P P +H      + P        +  +HP  
Sbjct: 331 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHP-------QAPGVHPAA 383

Query: 292 PFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRP 334
           P VH  +P    P    H P +  +HP+P     S+  +HP+P
Sbjct: 384 PAVHPQAPGVHPPAPGMH-PQAPGVHPQPPGVHPSAPGVHPQP 425



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 63/202 (31%), Positives = 85/202 (42%), Gaps = 28/202 (13%)

Query: 66  PCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF 125
           P P  H  +P+        H P+S    P P VH  +P    P    H P+S        
Sbjct: 283 PAPGVHPPAPV-------VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSG------- 328

Query: 126 VHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPR-PFVHA 184
           VH  +P   PP    H P+       P +H  +P   PP    H P S  +HP+ P VH 
Sbjct: 329 VHPPAPGVHPPAPGVHPPA-------PGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHP 381

Query: 185 SSPTALRPCLFTHGPSSMPLHPR-PFVHASSPTALPPCLFTHGPSSMPLHP-RPFVHASS 242
           ++P A+ P      P +  +HP+ P VH   P   P     H P    +HP  P VH  +
Sbjct: 382 AAP-AVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVH-PQPPGVHPSNPGVHPPT 439

Query: 243 --PTALRPCLFTHGPSSMPLHP 262
             P  LRP L + GP ++P  P
Sbjct: 440 PMPPMLRPPLPSEGPGNIPPPP 461



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 62/206 (30%), Positives = 82/206 (39%), Gaps = 34/206 (16%)

Query: 135 PPCLFTHGPSSMPLHPRPFLHASSPTA-LPPCLFTHGPSSMPLHPRPFVHASSPTALRPC 193
           PP L   GP  +   P P ++   P   LP  L    P  +PL P P      PT   P 
Sbjct: 220 PPSL-PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMP------PTGPAPS 272

Query: 194 LFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTH 253
               GP   P  P P     +P   PP    H P+S    P P VH  +P    P    H
Sbjct: 273 ----GPPGPPQLPPP-----APGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVH 323

Query: 254 GPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSS 313
            P+S    P P +H  +P    P    H P+       P VH  +P         H P S
Sbjct: 324 PPTSGVHPPAPGVHPPAPGVHPPAPGVHPPA-------PGVHPPAPG-------VHPPPS 369

Query: 314 MPLHPR-PFVHASSSTSLHPR-PFIH 337
             +HP+ P VH  ++ ++HP+ P +H
Sbjct: 370 AGVHPQAPGVH-PAAPAVHPQAPGVH 394



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 53/180 (29%), Positives = 72/180 (40%), Gaps = 18/180 (10%)

Query: 163 PPCLFTHGPSSMPLHPRPFVHASSPTALRP-CLFTHGPSSMPLHPRPFVHASSPTALPPC 221
           PP L   GP  +   P P ++   P    P  L    P  +PL P P     +P+  P  
Sbjct: 220 PPSL-PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPT-GPAPSGPP-- 275

Query: 222 LFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTH 281
               GP  +P  P P VH  +P         H P+S    P P +H  +P    P    H
Sbjct: 276 ----GPPQLP-PPAPGVHPPAPVV-------HPPASGVHPPAPGVHPPAPGVHPPAPGVH 323

Query: 282 GPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPR-PFIHASS 340
            P+S    P P VH  +P    P    H P+     P P VH   S  +HP+ P +H ++
Sbjct: 324 PPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAA 383


>gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo
           sapiens]
          Length = 475

 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 79/276 (28%), Positives = 114/276 (41%), Gaps = 66/276 (23%)

Query: 28  FPH----GSSTAL-----HPWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPM-- 76
           FPH    GSS AL     H W            P   THGP S+   P    H  S +  
Sbjct: 17  FPHKMPGGSSEALGTVRCHCWC-----------PHNGTHGPHSSGFQP----HNRSGLRV 61

Query: 77  -----SLHPRLFTHSPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVH 127
                S+HP +  H     P+HP   P +H+S+  ++   +  H  +   +HP   P VH
Sbjct: 62  NKGAASIHPPIHLH--IHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVH 119

Query: 128 ASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPC-LFTHGPSSMPLHP--RPFVHA 184
            S+  ++ P   TH  +   +H  PF+H   P   PP  L  H P    +HP   P +H 
Sbjct: 120 PSNHPSVHPS--THPSTHPSIH--PFIH---PPVHPPIHLHIHPPIHPSVHPSTHPLIHP 172

Query: 185 SSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASS 242
               ++ P +  H  + +  HP  RP VH S+  +  P +  H P   P+HP   +H S 
Sbjct: 173 PIHPSIHPPI--HPSTHLSTHPSIRPPVHPSTHPSTHPLI--HPPIHPPIHPS--IHPS- 225

Query: 243 PTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCL 278
                    TH P+  P+ P P  H S   +   C+
Sbjct: 226 ---------THPPTHPPV-PHPSTHPSIHPSYMGCI 251



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 67/233 (28%), Positives = 101/233 (43%), Gaps = 42/233 (18%)

Query: 112 THGPSSMPLHPRPF----VHASSPTALPPC-LFTHGPSSMPLHPRPFLHASSPTALPPCL 166
           THGP S    P       V+  + +  PP  L  H P    +HP   +H+S+  ++   +
Sbjct: 43  THGPHSSGFQPHNRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPP--MHSSTHPSIHLFI 100

Query: 167 FTHGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPC-LF 223
             H  +   +HP   P VH S+  ++ P   TH  +   +HP  F+H   P   PP  L 
Sbjct: 101 HIHSSTHPSIHPFIHPSVHPSNHPSVHPS--THPSTHPSIHP--FIH---PPVHPPIHLH 153

Query: 224 THGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHASSPTALRPCLF 279
            H P    +HP   P +H     ++ P +  H  + +  HP  RP +H S+  +  P + 
Sbjct: 154 IHPPIHPSVHPSTHPLIHPPIHPSIHPPI--HPSTHLSTHPSIRPPVHPSTHPSTHPLI- 210

Query: 280 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHP 332
            H P   P+HP   +H S          TH P+    HP P  H S+  S+HP
Sbjct: 211 -HPPIHPPIHPS--IHPS----------THPPT----HP-PVPHPSTHPSIHP 245



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 41/192 (21%)

Query: 168 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP------RPFVHASSPTALPPC 221
           THGP S    P    + S     +     H P  + +HP       P +H+S+  ++   
Sbjct: 43  THGPHSSGFQPH---NRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99

Query: 222 LFTHGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLF 279
           +  H  +   +HP   P VH S+  ++ P   TH  +   +HP  F+H            
Sbjct: 100 IHIHSSTHPSIHPFIHPSVHPSNHPSVHPS--THPSTHPSIHP--FIHPP---------- 145

Query: 280 THGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP--R 333
            H P  + +HP   P VH S+   + P          P+HP   P +H S+  S HP  R
Sbjct: 146 VHPPIHLHIHPPIHPSVHPSTHPLIHP----------PIHPSIHPPIHPSTHLSTHPSIR 195

Query: 334 PFIHASSSKSLH 345
           P +H S+  S H
Sbjct: 196 PPVHPSTHPSTH 207



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 61/195 (31%), Positives = 84/195 (43%), Gaps = 32/195 (16%)

Query: 9   LHP--RPFIHGFSFTTFLQQLFPHGSSTALHP--WPFIHGSSPMALHPRLFTHGPSSTAL 64
           +HP   P +H  +  +    LF H  S+  HP   PFIH S   + HP          ++
Sbjct: 80  IHPSIHPPMHSSTHPSI--HLFIHIHSST-HPSIHPFIHPSVHPSNHP----------SV 126

Query: 65  HPCPFTHGSSPMSLHPRLFTHSPSSMP--LHPRPFVHASSPTALRPCLFTHGPSSMPLHP 122
           HP   TH S+  S+HP  F H P   P  LH  P +H S   +  P +  H P    +HP
Sbjct: 127 HPS--THPSTHPSIHP--FIHPPVHPPIHLHIHPPIHPSVHPSTHPLI--HPPIHPSIHP 180

Query: 123 --RPFVHASS-PTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPR 179
              P  H S+ P+  PP   +  PS+ PL   P      P+  P    TH P+  P+ P 
Sbjct: 181 PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPS---THPPTHPPV-PH 236

Query: 180 PFVHASSPTALRPCL 194
           P  H S   +   C+
Sbjct: 237 PSTHPSIHPSYMGCI 251



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 29/133 (21%)

Query: 224 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHASSPTALRPC--LF 279
           THGP S    P    + S     +     H P  + +HP   P +H    ++  P   LF
Sbjct: 43  THGPHSSGFQPH---NRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99

Query: 280 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP--RPF 335
            H  SS      PF+H S                  +HP   P VH S+  S HP   PF
Sbjct: 100 IHIHSSTHPSIHPFIHPS------------------VHPSNHPSVHPSTHPSTHPSIHPF 141

Query: 336 IHASSSKSLHLRL 348
           IH      +HL +
Sbjct: 142 IHPPVHPPIHLHI 154



 Score = 32.7 bits (73), Expect = 0.57
 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%)

Query: 280 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP--RPF 335
           THGP S    P    + S     +     H P  + +HP   P +H    +S HP    F
Sbjct: 43  THGPHSSGFQPH---NRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99

Query: 336 IHASSSKSLHLRLFSHSS 353
           IH  SS    +  F H S
Sbjct: 100 IHIHSSTHPSIHPFIHPS 117


>gi|239753972 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 298

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 77/256 (30%), Positives = 113/256 (44%), Gaps = 58/256 (22%)

Query: 30  HGSST--ALHPWPF--IHGSSPMALHPRLFTHGP----SSTALHPC--PFTHGSSPMSLH 79
           H SST   +HP     IH S+ + +HP   TH P    ++  +HP   P  H S+  ++H
Sbjct: 53  HPSSTHPPIHPSTHLPIHPSTHLPIHPS--THPPIHPSTNPPIHPSTNPPIHPSTHPTIH 110

Query: 80  PRLFTHSPSS-MPLHP------RPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPT 132
           P   TH PS+ +P+HP       PF+H  +   + P      P+  P+HP       S  
Sbjct: 111 PS--THPPSTYLPIHPSAHPLIHPFIHPLTHLFIHP-----PPTHSPIHPP----THSSI 159

Query: 133 ALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHP--RPFVHASSPTAL 190
            LP  L  + P+   +HP P  H   P+  PP           +HP   P +H S+ T+ 
Sbjct: 160 HLPTHLSIYPPTYPSIHPPPTPH---PSIHPP-----------IHPSTHPLIHPSTHTST 205

Query: 191 RPCLFTHGPSSMPLHPRPFVHAS-SPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPC 249
            P   TH P+  P +P   +H+S  P   PP   TH  +  P+H     H S+  +  P 
Sbjct: 206 HPP--THPPTHPPSNPS--IHSSIHPPIHPP---THPSTHPPIHSS--THPSTYFSTHPP 256

Query: 250 LFTHGPSSMPLHPRPF 265
           L +  P  +    RPF
Sbjct: 257 LLS--PKVLQKAFRPF 270



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 57/232 (24%)

Query: 145 SMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPF--VHASSPTALRPCLFTHGPSSM 202
           + P HP   +H SS    PP    H  + +P+HP     +H S+   + P       ++ 
Sbjct: 45  NQPTHPT--IHPSSTH--PPI---HPSTHLPIHPSTHLPIHPSTHPPIHPS------TNP 91

Query: 203 PLHP--RPFVHASSPTALPPCLFTHGPSS-MPLHP------RPFVHASSPTALRPCLFTH 253
           P+HP   P +H S+   + P   TH PS+ +P+HP       PF+H  +   + P     
Sbjct: 92  PIHPSTNPPIHPSTHPTIHPS--THPPSTYLPIHPSAHPLIHPFIHPLTHLFIHP----- 144

Query: 254 GPSSMPLHPRPFLHASSPT----------ALRPCLFTHGPSSMPLHP--RPFVHASSPTA 301
            P+  P+HP        PT          ++ P    H     P+HP   P +H S+ T+
Sbjct: 145 PPTHSPIHPPTHSSIHLPTHLSIYPPTYPSIHPPPTPHPSIHPPIHPSTHPLIHPSTHTS 204

Query: 302 LRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP------RPFIHASSSKSLH 345
                 TH P+  P HP   P +H+S    +HP       P IH+S+  S +
Sbjct: 205 ------THPPTHPPTHPPSNPSIHSSIHPPIHPPTHPSTHPPIHSSTHPSTY 250



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 52/197 (26%), Positives = 77/197 (39%), Gaps = 35/197 (17%)

Query: 1   MHACSSTALHP--RPFIHGFSFTTFLQQLFPHGSSTALHP------WPFIHGSSPMALHP 52
           +H  ++  +HP   P IH  +  T      P  +   +HP       PFIH  + + +HP
Sbjct: 85  IHPSTNPPIHPSTNPPIHPSTHPTIHPSTHPPSTYLPIHPSAHPLIHPFIHPLTHLFIHP 144

Query: 53  RLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFT 112
                 P+ + +HP   TH S  +  H  L  + P+   +HP P  H S    + P    
Sbjct: 145 P-----PTHSPIHPP--THSSIHLPTH--LSIYPPTYPSIHPPPTPHPS----IHP---- 187

Query: 113 HGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHG 170
                 P+HP   P +H S+ T+  P   TH P+  P +P        P   P    TH 
Sbjct: 188 ------PIHPSTHPLIHPSTHTSTHPP--THPPTHPPSNPSIHSSIHPPIHPPTHPSTHP 239

Query: 171 PSSMPLHPRPFVHASSP 187
           P     HP  +     P
Sbjct: 240 PIHSSTHPSTYFSTHPP 256


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 71/282 (25%), Positives = 97/282 (34%), Gaps = 20/282 (7%)

Query: 59   PSSTALHPCPFTHGSSPMSL-HPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSS 117
            P ST   P P T  S P +   P   T SP +      P     SP    P       ++
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516

Query: 118  MPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLH 177
            +P    P    ++ T  PP      P++ P+ P      +S T LPP      P +    
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-----PTSTTTLPPTTTPSPPPTTTTT 1571

Query: 178  PRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPF 237
            P P    S PT   P   T   ++ P    P    ++ T  PP      P++ P+ P   
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP--- 1628

Query: 238  VHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHAS 297
               +S T L P      P +    P P    S PT   P      P +    P P    S
Sbjct: 1629 --PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP----SPPITTTTTPPPTTTPS 1682

Query: 298  SPTALRP-----CLFTHGPSSMPLHPRPFVHASSSTSLHPRP 334
            SP    P      + T  P++ P  P       SST+    P
Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 73/292 (25%), Positives = 101/292 (34%), Gaps = 21/292 (7%)

Query: 56   THGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGP 115
            T  P +T   P P +  + P +  P   T + ++ P    P    ++ T   P      P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 116  SSMPLHPRPFVHASSPTAL--PPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSS 173
             S    P P    S PT    PP      P++    P P    S PT  P    T   S+
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP---ITPPAST 1514

Query: 174  MPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMP 231
              L P      ++P+       T  P++ P  P   P    +S T LPP      P +  
Sbjct: 1515 TTLPP-----TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1569

Query: 232  LHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHP- 290
              P P    S PT   P      P+     P P    S PT       T  P++ P  P 
Sbjct: 1570 TTPPPTTTPSPPTTTTP----SPPTITTTTPPPTTTPSPPTTTTT---TPPPTTTPSPPT 1622

Query: 291  -RPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSS 341
              P    +S T L P      P +    P P    S  T+  P P I  +++
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674



 Score = 37.0 bits (84), Expect = 0.030
 Identities = 42/173 (24%), Positives = 59/173 (34%), Gaps = 14/173 (8%)

Query: 165  CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSP----TALPP 220
            C+ T  P +    P P    +S T L P      P++    P P    S P    T  PP
Sbjct: 1395 CITTPSPPTTTPSPPP----TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450

Query: 221  CLFTHGPSSMPLHPRPFVHASSPTAL-RPCLFTHGPSSMPLHPRPFLHASSPTALRPCLF 279
                  P S    P P    S PT    P   T  P +      P     SP    P   
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 280  THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHP 332
                +++P    P    ++ T   P      P++ P+ P      +S+T+L P
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-----PTSTTTLPP 1558


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 82/286 (28%), Positives = 117/286 (40%), Gaps = 41/286 (14%)

Query: 40  PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMP-LHPRPFV 98
           P +  SSP  L P   ++ P+ T  +    T  S+P        T +PSS P L P+P +
Sbjct: 40  PTLTPSSPPTLTP---SNTPTLTPSNTPTLTPSSTP--------TLTPSSTPTLTPQPIL 88

Query: 99  HASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASS 158
             SS            P+  P  P     +++PT  P    T  PS+ P        +S+
Sbjct: 89  TRSST-----------PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT----LTPSST 133

Query: 159 PTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHG-PSSMPLHPRPFVHASSPTA 217
           PT  P    T  PSS P+  R      +P++ RP L     P+  P        +S+PT 
Sbjct: 134 PTLTPSSTPTLTPSSRPILTRSSTPTLTPSS-RPILTRSSTPTLTPSSTPTLTPSSTPTL 192

Query: 218 LPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLF-----THGPSSMPLHPR---PFLHAS 269
            P    T  PSS P+  R      +P++ RP L      T  PSS P+  R   P L  S
Sbjct: 193 TPSSTPTLTPSSRPILTRSSTPTLTPSS-RPILTPSSTPTLTPSSRPILTRSSTPTLTPS 251

Query: 270 SPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMP 315
           S   L P   ++ P+  P +      +++PT       T  PSS P
Sbjct: 252 STPTLTP---SNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTP 294



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 81/271 (29%), Positives = 116/271 (42%), Gaps = 53/271 (19%)

Query: 84  THSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGP 143
           +++P+  P  P     +S+PT          PSS P+  R    +S+PT  P    T  P
Sbjct: 5   SNTPTLTPSSPPTLTPSSTPTLT--------PSSQPILTR----SSTPTLTPSSPPTLTP 52

Query: 144 SSMPLHPRPFLHASSPTALPPCLFTHGPSSMP-LHPRPFVHASSPTALRPCLFTHGPSSM 202
           S+ P        +++PT  P    T  PSS P L P+P +  SS   L P   +  P+  
Sbjct: 53  SNTPT----LTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTP---SSPPTLT 105

Query: 203 PLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP 262
           P +      +++PT  P    T  PSS P        +S+PT          PSS P+  
Sbjct: 106 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPT----LTPSSTPTLT--------PSSRPILT 153

Query: 263 RPFLHASSPTALRPCLFTHGPSSMPLHPR----PFVHASSPTALRPCLFTHGPSSMP-LH 317
           R    +S+PT          PSS P+  R        +S+PT       T  PSS P L 
Sbjct: 154 R----SSTPTLT--------PSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 201

Query: 318 P--RPFVHASSSTSLHP--RPFIHASSSKSL 344
           P  RP +  SS+ +L P  RP +  SS+ +L
Sbjct: 202 PSSRPILTRSSTPTLTPSSRPILTPSSTPTL 232


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 82/286 (28%), Positives = 117/286 (40%), Gaps = 41/286 (14%)

Query: 40  PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMP-LHPRPFV 98
           P +  SSP  L P   ++ P+ T  +    T  S+P        T +PSS P L P+P +
Sbjct: 40  PTLTPSSPPTLTP---SNTPTLTPSNTPTLTPSSTP--------TLTPSSTPTLTPQPIL 88

Query: 99  HASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASS 158
             SS            P+  P  P     +++PT  P    T  PS+ P        +S+
Sbjct: 89  TRSST-----------PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPT----LTPSST 133

Query: 159 PTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHG-PSSMPLHPRPFVHASSPTA 217
           PT  P    T  PSS P+  R      +P++ RP L     P+  P        +S+PT 
Sbjct: 134 PTLTPSSTPTLTPSSRPILTRSSTPTLTPSS-RPILTRSSTPTLTPSSTPTLTPSSTPTL 192

Query: 218 LPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLF-----THGPSSMPLHPR---PFLHAS 269
            P    T  PSS P+  R      +P++ RP L      T  PSS P+  R   P L  S
Sbjct: 193 TPSSTPTLTPSSRPILTRSSTPTLTPSS-RPILTPSSTPTLTPSSRPILTRSSTPTLTPS 251

Query: 270 SPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMP 315
           S   L P   ++ P+  P +      +++PT       T  PSS P
Sbjct: 252 STPTLTP---SNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTP 294



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 81/271 (29%), Positives = 116/271 (42%), Gaps = 53/271 (19%)

Query: 84  THSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGP 143
           +++P+  P  P     +S+PT          PSS P+  R    +S+PT  P    T  P
Sbjct: 5   SNTPTLTPSSPPTLTPSSTPTLT--------PSSQPILTR----SSTPTLTPSSPPTLTP 52

Query: 144 SSMPLHPRPFLHASSPTALPPCLFTHGPSSMP-LHPRPFVHASSPTALRPCLFTHGPSSM 202
           S+ P        +++PT  P    T  PSS P L P+P +  SS   L P   +  P+  
Sbjct: 53  SNTPT----LTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTP---SSPPTLT 105

Query: 203 PLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP 262
           P +      +++PT  P    T  PSS P        +S+PT          PSS P+  
Sbjct: 106 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPT----LTPSSTPTLT--------PSSRPILT 153

Query: 263 RPFLHASSPTALRPCLFTHGPSSMPLHPR----PFVHASSPTALRPCLFTHGPSSMP-LH 317
           R    +S+PT          PSS P+  R        +S+PT       T  PSS P L 
Sbjct: 154 R----SSTPTLT--------PSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 201

Query: 318 P--RPFVHASSSTSLHP--RPFIHASSSKSL 344
           P  RP +  SS+ +L P  RP +  SS+ +L
Sbjct: 202 PSSRPILTRSSTPTLTPSSRPILTPSSTPTL 232


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 68/236 (28%), Positives = 93/236 (39%), Gaps = 19/236 (8%)

Query: 80  PRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLF 139
           P L   SP ++     P +   S   L PC     P+  P +      +S+PT  P    
Sbjct: 52  PTLTPSSPPTLTPSNTPTLTPCSTPTLTPC---STPTLTPSNTPTLTPSSTPTLTPSSTP 108

Query: 140 THGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGP 199
           T  PSS P        +S+PT  P    T  PSS P   R    +S+PT       T  P
Sbjct: 109 TLTPSSTPT----LTPSSTPTLTPSSTPTLTPSSTPTLTR----SSTPTLTPSSTPTLTP 160

Query: 200 SSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMP 259
           SS P        +S+PT  P    T  PSS P+  R      +P++      +  P+  P
Sbjct: 161 SSTPT----LTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTP 216

Query: 260 LHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMP 315
            +    + +S+PT       T  PSS P   R    +S+PT       T  PSS P
Sbjct: 217 SNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTR----SSTPTLTPSSTPTLTPSSTP 268



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 71/248 (28%), Positives = 98/248 (39%), Gaps = 31/248 (12%)

Query: 40  PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVH 99
           P +  SSP  L P       ++  L PC  T   +P S        +P+  P +      
Sbjct: 52  PTLTPSSPPTLTPS------NTPTLTPCS-TPTLTPCS--------TPTLTPSNTPTLTP 96

Query: 100 ASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSP 159
           +S+PT       T  PSS P        +S+PT  P    T  PSS P   R    +S+P
Sbjct: 97  SSTPTLTPSSTPTLTPSSTPT----LTPSSTPTLTPSSTPTLTPSSTPTLTR----SSTP 148

Query: 160 TALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALP 219
           T  P    T  PSS P        +S+PT       T  PSS P+  R      +P++ P
Sbjct: 149 TLTPSSTPTLTPSSTPT----LTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTP 204

Query: 220 PCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLF 279
               +  P+  P +    + +S+PT       T  PSS P   R    +S+PT       
Sbjct: 205 TLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTR----SSTPTLTPSSTP 260

Query: 280 THGPSSMP 287
           T  PSS P
Sbjct: 261 TLTPSSTP 268



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 72/244 (29%), Positives = 96/244 (39%), Gaps = 40/244 (16%)

Query: 114 GPSSMPLHPR----PFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTH 169
           G  + P  PR    P +  SSP  L P   ++ P+  P         S+PT  P    T 
Sbjct: 38  GEMTGPYGPREMGTPTLTPSSPPTLTP---SNTPTLTPCSTPTLTPCSTPTLTPSNTPTL 94

Query: 170 GPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSS 229
            PSS P        +S+PT          PSS P        +S+PT  P    T  PSS
Sbjct: 95  TPSSTPT----LTPSSTPTLT--------PSSTPT----LTPSSTPTLTPSSTPTLTPSS 138

Query: 230 MPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLH 289
            P   R    +S+PT       T  PSS P        +S+PT       T  PSS P+ 
Sbjct: 139 TPTLTR----SSTPTLTPSSTPTLTPSSTPT----LTPSSTPTLTPSSTPTLTPSSRPIL 190

Query: 290 PR----PFVHASSPTALRPCLFTHGPSSMPL---HPRPFVHASSSTSLHP--RPFIHASS 340
            R        +S+PT       T  PS+ P       P +  SS+ +L P  RP +  SS
Sbjct: 191 TRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSS 250

Query: 341 SKSL 344
           + +L
Sbjct: 251 TPTL 254


>gi|239755199 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 279

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 65/207 (31%), Positives = 88/207 (42%), Gaps = 45/207 (21%)

Query: 68  PFTHGSSPMSLHPRLFTHSPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--R 123
           P  H S   S HP          P+HP   P +H S    + P +  H P+   +HP   
Sbjct: 49  PSIHPSIHPSTHP----------PIHPSIHPSIHPSIHPPVHPSI--HPPTRPSIHPSIH 96

Query: 124 PFVHASSPTALPPCLFTHGPSSMPLHPR--PFLHASSPTALPPCL--FTHGPSSMPLHPR 179
           P VH S+  +      TH     P+HP   P +H S+  ++ P +  F H     P HP 
Sbjct: 97  PPVHLSTHPS------THPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPTHPS 150

Query: 180 PFVHASS-PTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHPRP 236
             +HAS+ P    P   TH P+    HP   P +H   P A PP    H     P HP  
Sbjct: 151 --IHASTHPLIHHPS--THPPTHPSTHPSIHPTIH---PRAHPP---IHPSIHSPTHPS- 199

Query: 237 FVHASSPTALRPCLFTHGPSSMP-LHP 262
            +H S+  +  P   TH PS+ P +HP
Sbjct: 200 -IHPSTHPSTHP--LTH-PSTYPSIHP 222



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 54/168 (32%), Positives = 74/168 (44%), Gaps = 26/168 (15%)

Query: 198 GPSSMP-LHP--RPFVHASSPTALPPCLFTHGPSSMPLHP--RPFVHAS--SPTALRPCL 250
           GPS  P +HP   P +H S   ++ P +  H P    +HP  RP +H S   P  L    
Sbjct: 48  GPSIHPSIHPSTHPPIHPSIHPSIHPSI--HPPVHPSIHPPTRPSIHPSIHPPVHLSTHP 105

Query: 251 FTHGPSSMPLHPR--PFLHASSPTALRPCL--FTHGPSSMPLHPRPFVHASS-PTALRPC 305
            TH     P+HP   P +H S+  ++ P +  F H     P HP   +HAS+ P    P 
Sbjct: 106 STHPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPTHPS--IHASTHPLIHHPS 163

Query: 306 LFTHGPSSMPLHP--RPFVHASSSTSLHP------RPFIHASSSKSLH 345
             TH P+    HP   P +H  +   +HP       P IH S+  S H
Sbjct: 164 --THPPTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSIHPSTHPSTH 209



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 60/187 (32%), Positives = 83/187 (44%), Gaps = 43/187 (22%)

Query: 36  LHP--WPFIHGSSPMALHPRLFTHGPSSTALHPCPF------THGSSPMSLHPRLFTHSP 87
           +HP   P IH S    +HP +  H P+  ++HP         TH S+  S+HP       
Sbjct: 63  IHPSIHPSIHPSIHPPVHPSI--HPPTRPSIHPSIHPPVHLSTHPSTHPSIHP------- 113

Query: 88  SSMPLHPR--PFVHASSPTALRPCL--FTHGPSSMPLHPRPFVHASS-PTALPPCLFTHG 142
              P+HP   P +H S+  ++ P +  F H     P HP   +HAS+ P    P   TH 
Sbjct: 114 ---PIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPTHPS--IHASTHPLIHHPS--THP 166

Query: 143 PSSMPLHP--RPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPS 200
           P+    HP   P +H   P A PP    H     P HP   +H S+  +  P   TH PS
Sbjct: 167 PTHPSTHPSIHPTIH---PRAHPP---IHPSIHSPTHPS--IHPSTHPSTHP--LTH-PS 215

Query: 201 SMP-LHP 206
           + P +HP
Sbjct: 216 TYPSIHP 222



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 38/114 (33%), Positives = 53/114 (46%), Gaps = 13/114 (11%)

Query: 254 GPSSMP-LHP--RPFLHASSPTALRPCLFTHGPSSMPLHP--RPFVHAS--SPTALRPCL 306
           GPS  P +HP   P +H S   ++ P +  H P    +HP  RP +H S   P  L    
Sbjct: 48  GPSIHPSIHPSTHPPIHPSIHPSIHPSI--HPPVHPSIHPPTRPSIHPSIHPPVHLSTHP 105

Query: 307 FTHGPSSMPLHPR--PFVHASSSTSLHP--RPFIHASSSKSLHLRLFSHSSCLV 356
            TH     P+HP   P +H S+  S+HP   PFIH S     H  + + +  L+
Sbjct: 106 STHPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPTHPSIHASTHPLI 159



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 27/114 (23%)

Query: 1   MHACSSTALHP--RPFIHGF-------SFTTFLQQLFPHGSS-----TALHP--WPFIHG 44
           +H  +  ++HP   PFIH         S       L  H S+      + HP   P IH 
Sbjct: 123 IHLSTHPSIHPPIHPFIHPSIHPPTHPSIHASTHPLIHHPSTHPPTHPSTHPSIHPTIHP 182

Query: 45  SSPMALHPRLFTHGPSSTALHPC------PFTHGSSPMSLHPRLFTHSPSSMPL 92
            +   +HP +  H P+  ++HP       P TH S+  S+HP   T  P + PL
Sbjct: 183 RAHPPIHPSI--HSPTHPSIHPSTHPSTHPLTHPSTYPSIHP---TIHPLTYPL 231


>gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo
           sapiens]
          Length = 217

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 46/171 (26%), Positives = 76/171 (44%), Gaps = 22/171 (12%)

Query: 176 LHPRP--FVHASSPTALRPCLFTHGPSSMPLHPRPF--VHASSPTALPPCLF--THGPSS 229
           +HP    F+H S   ++ PC+  H P+   +HP  +  +H S    + P +   TH    
Sbjct: 9   IHPSTHIFIHPSIHPSIHPCI--HPPTYSSIHPPTYSSIHPSVHPHIHPSIHPSTHPHIH 66

Query: 230 MPLHPR-PFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPL 288
             +HP  P +H S   ++RP  ++       +HP    H S   ++ P +  H   S  +
Sbjct: 67  PSIHPSIPSIHPSIHPSIRPSTYSS------IHPST--HISIHPSIHPSIHLHIHPSTHI 118

Query: 289 HPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPR--PFIH 337
              P +H+S   +  P +    PS  PL   P +H S+   +HP+  P IH
Sbjct: 119 FIHPSIHSSIHASTHPHIH---PSIYPLFIHPSIHPSTHPPIHPQIHPSIH 166



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 53/203 (26%), Positives = 84/203 (41%), Gaps = 44/203 (21%)

Query: 36  LHP--WPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLH 93
           +HP  + FIH S+ + +HP +        ++HPC   H  +  S+HP  ++    S+  H
Sbjct: 1   MHPSIYIFIHPSTHIFIHPSIHP------SIHPC--IHPPTYSSIHPPTYSSIHPSVHPH 52

Query: 94  PRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSSMPLHPR 151
             P +H S+   + P +    PS   +HP   P +  S+ +++ P   TH      +HP 
Sbjct: 53  IHPSIHPSTHPHIHPSIH---PSIPSIHPSIHPSIRPSTYSSIHPS--THISIHPSIHPS 107

Query: 152 PFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVH 211
             LH    T +    F H          P +H+S   +  P +    PS  PL   P +H
Sbjct: 108 IHLHIHPSTHI----FIH----------PSIHSSIHASTHPHIH---PSIYPLFIHPSIH 150

Query: 212 ASSPTALPPCLFTHGPSSMPLHP 234
            S          TH P    +HP
Sbjct: 151 PS----------THPPIHPQIHP 163



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 11/129 (8%)

Query: 232 LHPRP--FVHASSPTALRPCLFTHGPSSMPLHPRPF--LHASSPTALRPCLF--THGPSS 285
           +HP    F+H S   ++ PC+  H P+   +HP  +  +H S    + P +   TH    
Sbjct: 9   IHPSTHIFIHPSIHPSIHPCI--HPPTYSSIHPPTYSSIHPSVHPHIHPSIHPSTHPHIH 66

Query: 286 MPLHPR-PFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRP--FIHASSSK 342
             +HP  P +H S   ++RP  ++    S  +   P +H S    +HP    FIH S   
Sbjct: 67  PSIHPSIPSIHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHIFIHPSIHS 126

Query: 343 SLHLRLFSH 351
           S+H     H
Sbjct: 127 SIHASTHPH 135



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 21/157 (13%)

Query: 1   MHACSSTALHPRPF--IHGFSFTTFLQQLFPH-----GSSTALHPWPFIHGSSPMALHPR 53
           +H      +HP  +  IH  ++++    + PH       ST  H  P IH S P ++HP 
Sbjct: 21  IHPSIHPCIHPPTYSSIHPPTYSSIHPSVHPHIHPSIHPSTHPHIHPSIHPSIP-SIHPS 79

Query: 54  LFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTH 113
           +      ST     P TH S   S+HP +  H   S  +   P +H+S   +  P +   
Sbjct: 80  IHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHIFIHPSIHSSIHASTHPHIH-- 137

Query: 114 GPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHP 150
            PS  PL   P +H S          TH P    +HP
Sbjct: 138 -PSIYPLFIHPSIHPS----------THPPIHPQIHP 163



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 24/156 (15%)

Query: 204 LHPRP--FVHASSPTALPPCLFTHGPSSMPLHPRPF--VHASSPTALRPCLF--THGPSS 257
           +HP    F+H S   ++ PC+  H P+   +HP  +  +H S    + P +   TH    
Sbjct: 9   IHPSTHIFIHPSIHPSIHPCI--HPPTYSSIHPPTYSSIHPSVHPHIHPSIHPSTHPHIH 66

Query: 258 MPLHPR-PFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL 316
             +HP  P +H S   ++RP  ++       +HP    H S   ++ P +  H   S  +
Sbjct: 67  PSIHPSIPSIHPSIHPSIRPSTYSS------IHPS--THISIHPSIHPSIHLHIHPSTHI 118

Query: 317 HPRPFVHASSSTSLHPR-------PFIHASSSKSLH 345
              P +H+S   S HP         FIH S   S H
Sbjct: 119 FIHPSIHSSIHASTHPHIHPSIYPLFIHPSIHPSTH 154


>gi|193788649 retinoic acid induced 2 [Homo sapiens]
          Length = 530

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 63/206 (30%), Positives = 73/206 (35%), Gaps = 29/206 (14%)

Query: 78  LHPRLFTHSPSSMPLHPRPFVHASSPTALRP------CLFTHGPSSMP--LHPRPFVHAS 129
           L P     SP  MP+H +  V  SS   L P       + T GP  +P  L    F H +
Sbjct: 78  LQPLCLGESPVVMPIHMQ--VEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLN 135

Query: 130 SPTALP---PCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHA-- 184
           SP  LP   PC      SS  +H   F  A  P A P  L    PS       PF     
Sbjct: 136 SPLVLPQEAPC------SSSTIHNNLFQGAEDPEAQPQLLDLRIPSQPQEPTLPFEAVLQ 189

Query: 185 ---SSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLH-----PRP 236
               S   L P      P   P+ P+PF    SP   P  L    P  +PL      P P
Sbjct: 190 NLFPSQGTLGPPPCQPPPGYAPVPPQPFSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIP 249

Query: 237 FVHASSPTALRPCLFTHGPSSMPLHP 262
                S  +     F   PSS  LHP
Sbjct: 250 IPMPQSSESKFSSSFPKPPSSFGLHP 275



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 60/208 (28%), Positives = 71/208 (34%), Gaps = 29/208 (13%)

Query: 132 TALPPCLFTHGPSSMPLHPRPFLHASSPTALPP------CLFTHGPSSMP--LHPRPFVH 183
           T L P      P  MP+H +  +  SS   L P       + T GP  +P  L    F H
Sbjct: 76  TVLQPLCLGESPVVMPIHMQ--VEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQH 133

Query: 184 ASSPTAL---RPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHA 240
            +SP  L    PC      SS  +H   F  A  P A P  L    PS       PF   
Sbjct: 134 LNSPLVLPQEAPC------SSSTIHNNLFQGAEDPEAQPQLLDLRIPSQPQEPTLPFEAV 187

Query: 241 -----SSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLH-----P 290
                 S   L P      P   P+ P+PF    SP      L    P  +PL      P
Sbjct: 188 LQNLFPSQGTLGPPPCQPPPGYAPVPPQPFSSPLSPLVPPATLLVPYPVIVPLPVPVPIP 247

Query: 291 RPFVHASSPTALRPCLFTHGPSSMPLHP 318
            P     S  +     F   PSS  LHP
Sbjct: 248 IPIPMPQSSESKFSSSFPKPPSSFGLHP 275



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 42/149 (28%), Positives = 52/149 (34%), Gaps = 15/149 (10%)

Query: 41  FIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPR-PFVH 99
           F H +SP+ L         SS+ +H   F     P +  P+L      S P  P  PF  
Sbjct: 131 FQHLNSPLVLPQEAPC---SSSTIHNNLFQGAEDPEA-QPQLLDLRIPSQPQEPTLPFEA 186

Query: 100 A-----SSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLH----- 149
                  S   L P      P   P+ P+PF    SP   P  L    P  +PL      
Sbjct: 187 VLQNLFPSQGTLGPPPCQPPPGYAPVPPQPFSSPLSPLVPPATLLVPYPVIVPLPVPVPI 246

Query: 150 PRPFLHASSPTALPPCLFTHGPSSMPLHP 178
           P P     S  +     F   PSS  LHP
Sbjct: 247 PIPIPMPQSSESKFSSSFPKPPSSFGLHP 275


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 86/307 (28%), Positives = 118/307 (38%), Gaps = 51/307 (16%)

Query: 59   PSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLH-PRPFVHASSPTALRPCLFTHGPSS 117
            P S        T  SS +S + R    SPS  P   P P +     T L P +  H P++
Sbjct: 1119 PESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTT 1178

Query: 118  MPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLH 177
               HP    H   PT +        P++ P   +PF   +  T +P    T         
Sbjct: 1179 P--HPTTTPH---PTTITHSTMIPDPTTTP---QPFTTITHSTMIPDPTTT--------- 1221

Query: 178  PRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHAS---SPTALPPCLFTHGPSSMPLHP 234
            P+PF      T   P   T  P++ P HP    H++    PT  P    T  P++MP HP
Sbjct: 1222 PQPFTTMQPTTT--PHSTTPHPTTTP-HPTTITHSTMIPDPTTTPQPFTTMQPTTMP-HP 1277

Query: 235  RPFVHASSPTALRPCLFTHGPSSMPLHPR--------PFLHASSPTALRPCLFTHGPSSM 286
                H   PT       T  P++ P HP         P+   +      P   T  PSS 
Sbjct: 1278 TTTPH---PTTTPHPTTTPHPTTTP-HPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSST 1333

Query: 287  PLHPRPFVHASSPTALRPCLF--THGPSSMP-LHPR-----PFVHASSST--SLHPRPFI 336
            P+        S PT+L   L   T  P+  P LHP+     P  H S+S   +L P P +
Sbjct: 1334 PV----ITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPAL 1389

Query: 337  HASSSKS 343
             +S S+S
Sbjct: 1390 ESSPSRS 1396



 Score = 36.6 bits (83), Expect = 0.040
 Identities = 61/256 (23%), Positives = 89/256 (34%), Gaps = 45/256 (17%)

Query: 115  PSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSP--TALPPCLFTHGPS 172
            P++  L P      +     PP L  HG +  P  P P      P  T   P   + GPS
Sbjct: 953  PTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPS 1012

Query: 173  SMPLHPRPFVHASSPTALRPC------LFTHGPSSMPLHPRP--------------FVHA 212
            + P  P P + + S   L P         +  P + P  P P              F  +
Sbjct: 1013 ASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALS 1072

Query: 213  SSPTALPPCLFTHGPSSMPLHPRPFVHASSP------TALRPC--LFTHGPSSMPLHPRP 264
            +  +++ P L T  PS  PL   P    S P      T+L P         ++  L   P
Sbjct: 1073 TPDSSVVPAL-TPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTP 1131

Query: 265  FLHASSPTALRPCLFTHGPSSMP-LHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVH 323
            +    S  +  P      PS  P   P P +     T L P +  H P++    P P   
Sbjct: 1132 YSSTVSEYSRSP---DPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTT----PHP--- 1181

Query: 324  ASSSTSLHPRPFIHAS 339
               +T+ HP    H++
Sbjct: 1182 ---TTTPHPTTITHST 1194


>gi|239755446 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 394

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 27/200 (13%)

Query: 152 PFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFT--HGPSSMPLHP--R 207
           P +H S  + + P +    PS  P    P +H+S+  ++ P +    H P+   +HP   
Sbjct: 114 PSIHPSINSFIHPSMH---PSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIH 170

Query: 208 PFVHASSPTALPPCLFTHGPSSMPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHPRPF 265
           PF+H S    + P +      S+ +HP   P ++ S   ++ P    H     P+HP   
Sbjct: 171 PFIHPS----IHPSIHLSIHQSI-IHPLIYPLIYLSIHPSIHPSF--HASIYPPIHPS-- 221

Query: 266 LHASSPTALRPCLF--THGPSSMPLHP-RPFVHASSPTALRPCLFTHGPSSMP-LHPRPF 321
           +H S+  ++ P +    H P  +  H   P VH+S  +++   +    PS+ P +HP   
Sbjct: 222 IHLSTHLSIHPPIHPSVHSPIHLSTHSIHPSVHSSIHSSIHSSIH---PSTHPSIHP--L 276

Query: 322 VHASSSTSLHPRPFIHASSS 341
           +H S   S+HP  F  A+ S
Sbjct: 277 IHPSIHLSIHPENFYEAALS 296



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 64/234 (27%), Positives = 102/234 (43%), Gaps = 53/234 (22%)

Query: 32  SSTALHPW--PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSS 89
           S  ++HP    FIH S   ++HP  F H P+   +H    TH S   S+HP +  H P+ 
Sbjct: 112 SHPSIHPSINSFIHPSMHPSIHP--FIHPPT---IHSS--THPSIHPSIHPSI--HPPTH 162

Query: 90  MPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSS 145
             +HP   PF+H S    + P +      S+ +HP   P ++ S   ++ P    H    
Sbjct: 163 PSIHPSIHPFIHPS----IHPSIHLSIHQSI-IHPLIYPLIYLSIHPSIHPSF--HASIY 215

Query: 146 MPLHPRPFLHASSPTALPPCLF--THGPSSMPLHP-RPFVHASSPTALRPCLFTHGPSSM 202
            P+HP   +H S+  ++ P +    H P  +  H   P VH+S  +++   +    PS+ 
Sbjct: 216 PPIHPS--IHLSTHLSIHPPIHPSVHSPIHLSTHSIHPSVHSSIHSSIHSSIH---PSTH 270

Query: 203 P-LHP--RPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHA--SSPTALRPCLF 251
           P +HP   P +H S                  +HP  F  A  S+ +  R C+F
Sbjct: 271 PSIHPLIHPSIHLS------------------IHPENFYEAALSTKSTSRMCIF 306



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 17/87 (19%)

Query: 264 PFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVH 323
           P +H S  + + P +    PS  P    P +H+S+  ++ P +             P +H
Sbjct: 114 PSIHPSINSFIHPSMH---PSIHPFIHPPTIHSSTHPSIHPSI------------HPSIH 158

Query: 324 ASSSTSLHP--RPFIHASSSKSLHLRL 348
             +  S+HP   PFIH S   S+HL +
Sbjct: 159 PPTHPSIHPSIHPFIHPSIHPSIHLSI 185



 Score = 32.7 bits (73), Expect = 0.57
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 7/66 (10%)

Query: 292 PFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHP--RPFIHASSSKSLH--LR 347
           P +H S  + + P +    PS  P    P +H+S+  S+HP   P IH  +  S+H  + 
Sbjct: 114 PSIHPSINSFIHPSMH---PSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIH 170

Query: 348 LFSHSS 353
            F H S
Sbjct: 171 PFIHPS 176


>gi|239749927 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 61/230 (26%), Positives = 103/230 (44%), Gaps = 44/230 (19%)

Query: 32  SSTALHPW--PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSS 89
           S  ++HP    FIH S   ++HP  F H P+   +H    TH S   S+HP +  H P+ 
Sbjct: 12  SHPSIHPSINSFIHPSMHPSIHP--FIHPPT---IHSS--THPSIHPSIHPSI--HPPTH 62

Query: 90  MPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALPPCLFTHGPSS 145
             +HP   PF+H S    + P +      S+ +HP   P ++ S   ++ P    H    
Sbjct: 63  PSIHPSIHPFIHPS----IHPSIHLSIHQSI-IHPLIYPLIYLSIHPSIHPSF--HASIY 115

Query: 146 MPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPF--VHASSPTALRPCLFTHGPSSMP 203
            P+HP   +H S+  ++ P          P+HP     +H S+  ++ P + +   SS+ 
Sbjct: 116 PPIHPS--IHLSTHLSIHP----------PIHPSVHSPIHLSTHLSIHPSVHSSIHSSI- 162

Query: 204 LHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHA--SSPTALRPCLF 251
                 +H S+  ++ P +  H    + +HP  F  A  S+ +  R C+F
Sbjct: 163 ---HSSIHPSTHPSIHPLI--HPSIHLSIHPENFYEAALSTKSTSRMCIF 207



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 53/201 (26%), Positives = 91/201 (45%), Gaps = 28/201 (13%)

Query: 152 PFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFT--HGPSSMPLHP--R 207
           P +H S  + + P +    PS  P    P +H+S+  ++ P +    H P+   +HP   
Sbjct: 14  PSIHPSINSFIHPSMH---PSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIH 70

Query: 208 PFVHASSPTALPPCLFTHGPSSMPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHPRPF 265
           PF+H S    + P +      S+ +HP   P ++ S   ++ P    H     P+HP   
Sbjct: 71  PFIHPS----IHPSIHLSIHQSI-IHPLIYPLIYLSIHPSIHPSF--HASIYPPIHPS-- 121

Query: 266 LHASSPTALRPCLF--THGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMP-LHPRP 320
           +H S+  ++ P +    H P  +  H    P VH+S  +++   +    PS+ P +HP  
Sbjct: 122 IHLSTHLSIHPPIHPSVHSPIHLSTHLSIHPSVHSSIHSSIHSSIH---PSTHPSIHP-- 176

Query: 321 FVHASSSTSLHPRPFIHASSS 341
            +H S   S+HP  F  A+ S
Sbjct: 177 LIHPSIHLSIHPENFYEAALS 197



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 48/186 (25%), Positives = 83/186 (44%), Gaps = 32/186 (17%)

Query: 180 PFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFT--HGPSSMPLHP--R 235
           P +H S  + + P +    PS  P    P +H+S+  ++ P +    H P+   +HP   
Sbjct: 14  PSIHPSINSFIHPSMH---PSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIH 70

Query: 236 PFVHASSPTALRPCLFTHGPSSMPLHPR--PFLHASSPTALRPCLFTHGPSSMPLHPRPF 293
           PF+H S    + P +      S+ +HP   P ++ S   ++ P    H     P+HP   
Sbjct: 71  PFIHPS----IHPSIHLSIHQSI-IHPLIYPLIYLSIHPSIHPSF--HASIYPPIHPS-- 121

Query: 294 VHASSPTALRPCLF--THGP----SSMPLHP--RPFVHASSSTSLHP------RPFIHAS 339
           +H S+  ++ P +    H P    + + +HP     +H+S  +S+HP       P IH S
Sbjct: 122 IHLSTHLSIHPPIHPSVHSPIHLSTHLSIHPSVHSSIHSSIHSSIHPSTHPSIHPLIHPS 181

Query: 340 SSKSLH 345
              S+H
Sbjct: 182 IHLSIH 187



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 22/156 (14%)

Query: 208 PFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFT--HGPSSMPLHP--R 263
           P +H S  + + P +    PS  P    P +H+S+  ++ P +    H P+   +HP   
Sbjct: 14  PSIHPSINSFIHPSMH---PSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIH 70

Query: 264 PFLHASSPTALRPCLFTHGPSSMPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHPRPF 321
           PF+H S    + P +      S+ +HP   P ++ S   ++ P    H     P+HP   
Sbjct: 71  PFIHPS----IHPSIHLSIHQSI-IHPLIYPLIYLSIHPSIHPSF--HASIYPPIHPS-- 121

Query: 322 VHASSSTSLHP--RPFIHASSSKSLHLRLFS--HSS 353
           +H S+  S+HP   P +H+    S HL +    HSS
Sbjct: 122 IHLSTHLSIHPPIHPSVHSPIHLSTHLSIHPSVHSS 157



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 30/170 (17%)

Query: 1   MHACSSTALHP------RPFIHGFSFTTFLQQLFPHGSSTALHP--WPFIHGSSPMALHP 52
           +H     ++HP       P IH F   +    +      + +HP  +P I+ S   ++HP
Sbjct: 49  IHPSIHPSIHPPTHPSIHPSIHPFIHPSIHPSIHLSIHQSIIHPLIYPLIYLSIHPSIHP 108

Query: 53  RLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPF--VHASSPTALRPCL 110
               H      +HP    H S+ +S+HP          P+HP     +H S+  ++ P +
Sbjct: 109 SF--HASIYPPIHPS--IHLSTHLSIHP----------PIHPSVHSPIHLSTHLSIHPSV 154

Query: 111 FTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPT 160
            +   SS+       +H S+  ++ P +  H    + +HP  F  A+  T
Sbjct: 155 HSSIHSSI----HSSIHPSTHPSIHPLI--HPSIHLSIHPENFYEAALST 198


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 91/304 (29%), Positives = 118/304 (38%), Gaps = 45/304 (14%)

Query: 45  SSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHP-----RLFTHSP----SSMPLHPR 95
           S P+     L    P  T+L P   +  SSP+++HP      L +HSP    SS+ + P 
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512

Query: 96  PFVHASSPTALR--PCLFTHGP-SSMP-LHPRPFVHASSPTALP---------PCLFTHG 142
               + +P +L+  P   T  P  ++P L P P   AS+P   P         PC     
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572

Query: 143 PSSMPLHP--RPFLHASSPTALPPCLFT---HGPSSMPLHP--RPFVHASSPTALRPCLF 195
           PS +   P   P   A+ P   PP L +    G  S PL P   P   A    AL P   
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632

Query: 196 THG-PSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHAS-SPTALRPCLFTH 253
               P+S PL P       +P AL   L    P S P  P P V A  SP A  P     
Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVHLL-QAPFSPP--PSPPVQAPFSPPASPPV---- 685

Query: 254 GPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSPTALRPCLFTHGP 311
            PS+ P    P   A+ P  + P      P+S P+ P   P   A  P A  P      P
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPP----SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 312 SSMP 315
            + P
Sbjct: 742 PASP 745



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 91/333 (27%), Positives = 121/333 (36%), Gaps = 53/333 (15%)

Query: 46  SPMALHPRLFTHGPSSTALHPC---PFTHGSSPMSLHPRLFTHSPSSMPLH--PRPFVHA 100
           SP+A  P      P   AL P    P    S P+S        +P+++ +H    PF   
Sbjct: 612 SPLATPP---PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668

Query: 101 SSPTALRPCLFTHGPSSMPLHPRPFVHASSPTAL----------PPCLFTHGPSSMPLHP 150
            SP    P      P+S P+ P     + +P +L          PP      PS+ P   
Sbjct: 669 PSPPVQAPF---SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725

Query: 151 RPFLHASSPTALPPCLFTHGPSSMPLHPRPFVH---ASSPTALRPCLFTHGPSSMPLHPR 207
            P   A+ P  +PP      P S    P P V    A+ P  + P      P+S+P+ P 
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP----SPPASLPMSPL 781

Query: 208 PFVHASSPTALPPCLFTHGPSSMPLHPRPFVHAS--SPTALRPC--LFTHGPSSMPLHPR 263
               A  P   PP L T    ++P  P  F   +  SP+A  P   L T  P + P+   
Sbjct: 782 ----AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837

Query: 264 PFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSP---TALRPCLFTHGPSSMPLHPRP 320
           P L         P L    P   P  P P    S P    AL P     GP      P P
Sbjct: 838 PLLQVPPSPPASPTL--QAPRRPPT-PGPDTSVSGPRLTLALAP-----GP------PPP 883

Query: 321 FVHASSSTSLHPRPFIHASSSKSLHLRLFSHSS 353
              + SST   P    H+SS+ S    L  + S
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 75/261 (28%), Positives = 97/261 (37%), Gaps = 41/261 (15%)

Query: 75  PMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTAL 134
           P+S  P L T SPS     P P        A  P   T  PS     P P     SP+A 
Sbjct: 298 PLSSSP-LATPSPSGTKARPVP----PPDNAATPLPATLPPSPPLATPLPLA-PPSPSAP 351

Query: 135 PPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHA-SSPTALRPC 193
           P       P + P    P    + P   PP L T  P  +P       H+ +SP+   P 
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP-------HSLTSPSLQAP- 403

Query: 194 LFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTH 253
                PS + L     + A++    P    TH  S + + PR    AS  +  RP   + 
Sbjct: 404 -----PSPLALSS---LQATTSLGSPTLQATH--SFLTMSPRQ-TQASLTSPSRPA--ST 450

Query: 254 GPSSMPLHPRPFLHASSP--TALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGP 311
            P S PL     L AS P  T+L P +    P S PL   P    SS       L +H P
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAV---SPLSSPLTIHPLQALSS-------LASHSP 500

Query: 312 SSMPLHPRPFVHASSSTSLHP 332
            + PL         + +SL P
Sbjct: 501 QA-PLSSLIMPPLETQSSLAP 520


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 88/319 (27%), Positives = 106/319 (33%), Gaps = 49/319 (15%)

Query: 27   LFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHS 86
            L P      L P P     SP    P L +  P    L P P     SP S  P L    
Sbjct: 788  LSPQAEGPHLSPQPEELHLSPQTEEPHL-SPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846

Query: 87   PSSM--------PLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCL 138
              S         PL PRP      P           P  +PL P P   + SP    P L
Sbjct: 847  EESHLSPELEKPPLSPRPEKPPEEPGQCP------APEELPLFPPPGEPSLSPLLGEPAL 900

Query: 139  FTHGPSSMPLHPRPF---LHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLF 195
                P   PL P P    L  S   +L P L    P   PL P   + A++P AL P   
Sbjct: 901  SE--PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP--IITAAAPPALSPL-- 954

Query: 196  THGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGP 255
              G    P   +      SP A P           P+ P P  + + P  + P +    P
Sbjct: 955  --GELEYPFGAKGDSDPESPLAAPIL-------ETPISPPPEANCTDPEPVPPMILPPSP 1005

Query: 256  SSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTA--LRPCLFTHGPSS 313
             S P+ P      +SP  + P      P   PL     V  +SP +    P L    PS 
Sbjct: 1006 GS-PVGP------ASPILMEPL----PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS- 1053

Query: 314  MPLHP-RPFVHASSSTSLH 331
             PL P    V  S    LH
Sbjct: 1054 -PLSPIGKVVGVSDEAELH 1071



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 81/309 (26%), Positives = 104/309 (33%), Gaps = 49/309 (15%)

Query: 59  PSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRP-FVHASSPTALRPCL------- 110
           P  + L P P    +SP     RL +  P  +P  P P  +H S P    P         
Sbjct: 444 PEESPLSPPPEESPTSPPPEASRL-SPPPEELPASPLPEALHLSRPLEESPLSPPPEESP 502

Query: 111 FTHGPSSMPLHPRPFVHASSPTALPP-----CLFTHGPSSMPLHPRPFLHA-------SS 158
            +  P S P  P      S P   PP        +  P + PL P PF  +         
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP-PFEESPLSPPPEEL 561

Query: 159 PTALPP--CLFTHGPSSMPLHPRPFVHASSPTALRPCLF--------THGPSSMPLHPRP 208
           PT+ PP     +  P   P+ P P     SP      LF        +  P   PL P P
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621

Query: 209 FVHASSPTALPP--CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFL 266
                SP   PP     +  P   P+ P P V   SP  +   L +  P   PL P P  
Sbjct: 622 EASRLSP---PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL-SPPPEESPLSPPP-- 675

Query: 267 HASSPTALRP--CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHA 324
              SPT+  P     +  P   P  P P    +SP      +      S+PL   P +  
Sbjct: 676 -EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM------SLPLEESPLLPL 728

Query: 325 SSSTSLHPR 333
                L PR
Sbjct: 729 PEEPQLCPR 737



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 71/273 (26%), Positives = 88/273 (32%), Gaps = 41/273 (15%)

Query: 72  GSSPMSLHPRLFTHSPSSMPLHPRPFVH------ASSPTALRP--CLFTHGPSSMPLHPR 123
           G + + L P+L       MPL P P           SPT+  P     +  P  +P  P 
Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479

Query: 124 P-FVHAS-----SPTALPP--CLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMP 175
           P  +H S     SP + PP     +  P S P  P      S P   PP      P S P
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP 539

Query: 176 LHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPR 235
               P       + L P      P  +P  P P     SP           P   P+ P 
Sbjct: 540 PEASPLSPPFEESPLSP-----PPEELPTSPPPEASRLSPP----------PEESPMSPP 584

Query: 236 PFVHASSPTALRPCLF--------THGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMP 287
           P     SP      LF        +  P   PL P P     SP        +  P   P
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP-EDSPMSPPPEESP 643

Query: 288 LHPRPFVHASSPTALRPCLFTHGPSSMPLHPRP 320
           + P P V   SP  +   L +  P   PL P P
Sbjct: 644 MSPPPEVSRLSPLPVVSRL-SPPPEESPLSPPP 675



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 98/327 (29%), Positives = 116/327 (35%), Gaps = 81/327 (24%)

Query: 35   ALH----PWPFIHGSSPMALHPRLFTHGPSSTA---------LHPCPFTHGSSPMSLHP- 80
            ALH    P P   GS P A  P +F   P++ A         L P     GS P    P 
Sbjct: 2101 ALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP---PAGSVPGPDSPG 2157

Query: 81   RLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFT 140
             LF   P  +P      V +  P  L P        + PL PR       PTA P     
Sbjct: 2158 ELFLKLPPQVPAQ----VPSQDPFGLAP--------AYPLEPR------FPTAPPTYPPY 2199

Query: 141  HGPSSMPLHPRPFLHASS-PTALPPCLFTHGPSSMPLH----PRPFVHASSPTALRPCL- 194
              P+  P  P P L ASS P A  P  F   P   P H    P PF+    P+     + 
Sbjct: 2200 PSPTGAPAQP-PMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVP 2258

Query: 195  ----FTHGPSSMPL-HPRPF-------------VHASSPTALPPCL-FTHGPSSMPLHPR 235
                   G +S PL  P PF             + ASSP+  PP L F   PSS      
Sbjct: 2259 ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSG----- 2313

Query: 236  PFVHASSPTALRPCLFTHGPSSMPLHPRPF-LHASSP-TALRPCLFTHGPSSMPLHPRPF 293
               H        P +F       PL PR   +   SP   LRP      P +  L P P 
Sbjct: 2314 --THLGGLELKTPDVF-----KAPLTPRASQVEPQSPGLGLRP---QEPPPAQALAPSPP 2363

Query: 294  VHASSPTALRPCLFTHGPSSMPLHPRP 320
             H   P   RP  +T   +  PL PRP
Sbjct: 2364 SH---PDIFRPGSYTDPYAQPPLTPRP 2387



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 79/273 (28%), Positives = 96/273 (35%), Gaps = 63/273 (23%)

Query: 86   SPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLH----PRPFVHASSPT----ALP-- 135
            SP+  P  P     +S P A +P  F   P   P H    P PF+    P+    A+P  
Sbjct: 2201 SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPES 2260

Query: 136  PCLFTHGPSSMPLHPRPF-------------LHASSPTALPPCL-FTHGPSS-------- 173
            P +     S   L P PF             L ASSP+  PP L F   PSS        
Sbjct: 2261 PGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320

Query: 174  --------MPLHPRPF-VHASSP-TALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLF 223
                     PL PR   V   SP   LRP      P +  L P P    S P    P  +
Sbjct: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRP---QEPPPAQALAPSP---PSHPDIFRPGSY 2374

Query: 224  THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGP 283
            T   +  PL PRP      P     C     P S+P  P   + AS          +   
Sbjct: 2375 TDPYAQPPLTPRP-----QPPPPESCC-ALPPRSLPSDPFSRVPASPQ--------SQSS 2420

Query: 284  SSMPLHPRPF-VHASSPTALRPCLFTHGPSSMP 315
            S  PL PRP    A  P+ + P   +  P S P
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 66/252 (26%), Positives = 86/252 (34%), Gaps = 50/252 (19%)

Query: 29   PHGSSTALHPWPFIHGSSPMALHPRLFTHG--PSSTALHPCPFTHGSSPMSLHPRLFTHS 86
            P      L P P     SP+   P L   G  P S      P +    P SL P+L    
Sbjct: 875  PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP-SLSPQLMPPD 933

Query: 87   PSSMPLHPRPFVHASSPTALRPCLFTHGPSSM-----------------PLHPRPFVHAS 129
            P   PL P   + A++P AL P      P                    P+ P P  + +
Sbjct: 934  PLPPPLSP--IITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT 991

Query: 130  SPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTA 189
             P  +PP +    P S P+ P      +SP  + P      P   PL     V  +SP +
Sbjct: 992  DPEPVPPMILPPSPGS-PVGP------ASPILMEPL----PPQCSPLLQHSLVPQNSPPS 1040

Query: 190  LRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPS-SMPLHPRPFVHASSP--TAL 246
               C     P ++PL        S P+ L P     G S    LH       S P   AL
Sbjct: 1041 --QC----SPPALPL--------SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPAL 1086

Query: 247  RPCLFTHGPSSM 258
             P   +  PS M
Sbjct: 1087 EPSATSPLPSPM 1098



 Score = 35.8 bits (81), Expect = 0.068
 Identities = 72/251 (28%), Positives = 87/251 (34%), Gaps = 44/251 (17%)

Query: 37   HPWPFIHGS--SPMA---LHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRL-FTHSPSSM 90
            HP  F  GS   P A   L PR     P S    P P +  S P S  P    + S S  
Sbjct: 2365 HPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP-PRSLPSDPFSRVPASPQSQSSSQS 2423

Query: 91   PLHPRPF-VHASSPTALRPCLFTHGPSSMP-LHPR---PF--VHASSPTALPPCLFTHG- 142
            PL PRP    A  P+ + P   +  P S P   P+   PF  +H       P   F  G 
Sbjct: 2424 PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGS 2483

Query: 143  -----------PSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALR 191
                       P+++P  P   LHA  P+  PP  F   P +       FV   SP    
Sbjct: 2484 LAHTSLGAGGFPAALPAGPAGELHAKVPSGQPP-NFVRSPGT-----GAFVGTPSPMRFT 2537

Query: 192  PCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLF 251
                   PS  P  P+P         LPP    HG +S    P P +     T       
Sbjct: 2538 FPQAVGEPSLKPPVPQP--------GLPP---PHGINS-HFGPGPTLGKPQSTNYTVATG 2585

Query: 252  THGPSSMPLHP 262
               PS  PL P
Sbjct: 2586 NFHPSGSPLGP 2596



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 9/98 (9%)

Query: 40   PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVH 99
            P  H SSP AL P L   G     + P   +  +   S      TH    + +   P   
Sbjct: 4005 PLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPS------THQGGPLAIGTTPESM 4058

Query: 100  ASSPTALRPCLFTHGPSSMPL-HPRPFVHASSPTALPP 136
            A+ P  ++P L   G S + L  P+P    SS    PP
Sbjct: 4059 ATEPGEVKPSL--SGDSQLLLVQPQPQPQPSSLQLQPP 4094


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 75/282 (26%), Positives = 101/282 (35%), Gaps = 47/282 (16%)

Query: 56   THGPSSTALHPCPFTHGSSPMSLH----PRLFTHSPSSM--------PLHPRP------F 97
            TH P+  +    P     +P+S      P   T +PS +        P  P P       
Sbjct: 853  THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912

Query: 98   VHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHAS 157
            + +SSP   R    T  P  +P  P P    + P A PP      P   P  P P    +
Sbjct: 913  MTSSSPKKARA---TPAPKGIPASPSPKGAPTPPAATPP-----SPKGGPATPSPKWAPT 964

Query: 158  SPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTA 217
             P A PP      P   P  P P    + P A  P      P   P  P P     +PT 
Sbjct: 965  PPAATPP-----SPKGGPATPSPKGAPTPPAATPP-----SPKGGPATPSP---KGAPT- 1010

Query: 218  LPPCLFTHGPSSMPLHPRPFVH-ASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRP 276
             PP +    P   P    PF   AS+P A  P      P++ PL   P    ++P A  P
Sbjct: 1011 -PPAVTPPSPKGSPA-ATPFPKGASTPPAATPPSPKGSPAATPL---PKGAPTTPAATLP 1065

Query: 277  CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP 318
                 GP++  L   P   A++P + +    T  P   P+ P
Sbjct: 1066 SP-KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 72/274 (26%), Positives = 104/274 (37%), Gaps = 40/274 (14%)

Query: 46   SPMALHPRLFTHGPSSTALHPCPFTHGSS-PMSLHPRLFTHSPSSMPLHPRPFVHASSPT 104
            +P A+ P      P++T     PF  G+S P +  P     SP++ PL   P    ++P 
Sbjct: 1010 TPPAVTPPSPKGSPAAT-----PFPKGASTPPAATPPSPKGSPAATPL---PKGAPTTPA 1061

Query: 105  ALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPP 164
            A  P      P   P  P      + P A PP      P   P  P P      P A PP
Sbjct: 1062 ATLP-----SPKGGPATPSLKGAPTPPAATPP-----SPKGGPATPSPKGAPMPPAATPP 1111

Query: 165  CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFT 224
                 G ++ P    P   A++P + +  L T  P   P  P     A++P +    L T
Sbjct: 1112 SP-KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP-----AATPPSPKGGLAT 1165

Query: 225  HGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPS 284
              P   P  P     A++P + +  L T  P   P  P     A++P + +  L T  P 
Sbjct: 1166 PPPKGAPTTP-----AATPPSPKGGLATPSPKGAPTTP-----AATPPSPKGGLATPSPK 1215

Query: 285  SMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP 318
              P  P     A++P + +  L T  P   P  P
Sbjct: 1216 GAPTTP-----AATPPSPKGGLATPSPKGAPTTP 1244



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 70/289 (24%), Positives = 93/289 (32%), Gaps = 38/289 (13%)

Query: 59   PSSTALHP-CPFTHGSSPMSLHPRLFTHSPSSMPLHPRP--------FVHASSPTALRPC 109
            P++T L    P T       + P +   SP   P  P P           ASSP A+ P 
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS 1588

Query: 110  LFTHGPSSMPLHPRPFVHASSP--TALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLF 167
             +   PS   L   P V + SP     PP +    P   P  P P    +SP   P  L 
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLK 1648

Query: 168  THGPS----------SMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTA 217
                S          ++P   +       PTAL+  L    P S P+        ++PT 
Sbjct: 1649 DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI-------ITAPTR 1701

Query: 218  LPPCLFTHGPSSMPLHPRPFVHAS-----SPTALRPCLFTHGPSSMPLHPRPFLHASSPT 272
              P       +S P+ P P          S  A  P L     SS     +   H+    
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761

Query: 273  ALRPCLFTHGPSSMPLHPRPFVHA-SSPTALRPCLFTHGPSSMPLHPRP 320
               P       +S PL    F      P +         P S+PL P P
Sbjct: 1762 LAPP----ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 74/330 (22%), Positives = 101/330 (30%), Gaps = 57/330 (17%)

Query: 46   SPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTA 105
            +P  + P     GP+++     P    ++P S      T  P   P  P   V   SP  
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA--VTPPSPKG 1345

Query: 106  LRPCLFTHGPSSM--PLHPRPFVHASSPTALP-----PCLFTHGPSSMPLHPRPFLHASS 158
              P L    PSS   P  P      + P A P     P +    P   P  P P    +S
Sbjct: 1346 T-PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404

Query: 159  PTALP-------PCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVH 211
            P  +P           T   ++ P        A +P +L+    T  P   P  P     
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464

Query: 212  ASSPTALPPC----------LFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLH 261
             + P   PP             +  P   P  P P     +PT   P +    P  +P  
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM---GAPTL--PAVIPSSPKEVPAT 1519

Query: 262  PRPFLHASSPTA-----------------LRPCLFTHGPSSMPLHPRP--------FVHA 296
            P       +PTA                 + P +    P   P  P P           A
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579

Query: 297  SSPTALRPCLFTHGPSSMPLHPRPFVHASS 326
            SSP A+ P  +   PS   L   P V + S
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 48/169 (28%), Positives = 61/169 (36%), Gaps = 25/169 (14%)

Query: 143 PSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSM 202
           P S  L     L    PT  PPC  +  P   PL        S+     P       +S 
Sbjct: 27  PMSSALSVTAALGQPGPTLPPPC--SPAPQQCPL--------SAANQASPFPSPSTIAST 76

Query: 203 PLHPRPFVHASSPTALPPCLFTHGPSSMP--LHP--RPFVHASSPTALRPCLFTHGPSSM 258
           PL   PF  +SS TALP       P+ +P  + P   P   A +   + P L     SS 
Sbjct: 77  PLEV-PFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA 135

Query: 259 PLHPRPFLHASSP------TALRPCLFTHGPSSMPLHPRPFVHASSPTA 301
           PL     L A +P      +A  P L T  PS         +  S+P A
Sbjct: 136 PL----ALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 96/345 (27%), Positives = 116/345 (33%), Gaps = 42/345 (12%)

Query: 29  PHGSSTALHPWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHG-SSPMSLHPRLFTHSP 87
           PH SS        +  + P    P      PS  A  P   T    SP       F  SP
Sbjct: 325 PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384

Query: 88  SSMPLHPRPFVHASSPTALRPCLFTHGP-SSMPLHPRPFVHASSPTAL-----------P 135
              PL   P   A    AL P      P +S PL P       +P AL           P
Sbjct: 385 PLSPLATPP-PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443

Query: 136 PCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLF 195
           P      P S P  P     A+ P+  PP L     ++ PL   P   AS P  + P   
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSL-----AAPPLQVPPSPPASPP--MSPSAT 496

Query: 196 THGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHAS--SPTALRPC--LF 251
               +  PL   P   A  P   PP L T    ++P  P  F   +  SP+A  P   L 
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556

Query: 252 THGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSP---TALRPCLFT 308
           T  P + P+   P L         P L    P   P  P P    S P    AL P    
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTL--QAPRRPPT-PGPDTSVSGPRLTLALAP---- 609

Query: 309 HGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKSLHLRLFSHSS 353
            GP      P P   + SST   P    H+SS+ S    L  + S
Sbjct: 610 -GP------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 647


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 85/303 (28%), Positives = 101/303 (33%), Gaps = 49/303 (16%)

Query: 52  PRLFTHGP--SSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPC 109
           P+L T GP  S+TA+ P     GS   S  P     +    P  P P  H     AL P 
Sbjct: 205 PQLPTPGPTPSATAVPP----QGSPTASQAP-----NQPQAPTAPVPHTHIQQAPALHP- 254

Query: 110 LFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTH 169
                    P  P P  H S    L P   + G  S P H +P LH   P    P     
Sbjct: 255 -------QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG--PHSLQA 305

Query: 170 GP-SSMPLHPRPF------VHASSPTALRP-CLFTHGPSSMPLHPRPFVHASSP--TALP 219
           GP    P  P+PF          +P    P   + H    +P           P    LP
Sbjct: 306 GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 365

Query: 220 PCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF---LHASSPTALRP 276
           P      P +MP H +P      P    P    H P      P PF    +   P AL+P
Sbjct: 366 P-----APLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLS--GPSPFSMNANLPPPPALKP 417

Query: 277 --CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLH--- 331
              L TH P S    P   +  S P    P        S  L P P  H    T LH   
Sbjct: 418 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--PPTGLHQVA 475

Query: 332 PRP 334
           P+P
Sbjct: 476 PQP 478



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 74/286 (25%), Positives = 87/286 (30%), Gaps = 45/286 (15%)

Query: 38  PWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPL--HPR 95
           P P  H S    L P   + G  S   H  P  HG  P         HS  + PL  HP 
Sbjct: 260 PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG------PHSLQAGPLLQHPG 313

Query: 96  PFVHASSPTALRPCLFTHGPSSMPLHPR---PFVHASSPTALPPCLFTHGPSSMPLHPRP 152
           P      P  L P   + G + +   P    P      P +         P   PL P P
Sbjct: 314 P----PQPFGLPP-QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368

Query: 153 FLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHA 212
               + P   PP       + +P  P P  H   P    P  F+   +  P         
Sbjct: 369 L---AMPHIKPP-----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP--------- 411

Query: 213 SSPTALPP--CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASS 270
             P AL P   L TH P S    P   +  S P    P        S  L P P  H   
Sbjct: 412 --PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--P 467

Query: 271 PTALRPCLFTHGPSSMPLHPRPFVHASSPTALRP-CLFTHGPSSMP 315
           PT L            P    PFV    P    P C  T  P + P
Sbjct: 468 PTGLHQV-----APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 508



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 42/149 (28%), Positives = 46/149 (30%), Gaps = 19/149 (12%)

Query: 154 LHASSPTALPPCLFTHGPSSMPLH--------PRPFVHASSPTALRPCLFTHGPSSMPLH 205
           L A  P    P   T  PSS P          P P   A  P               P  
Sbjct: 180 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTA 239

Query: 206 PRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF 265
           P P  H     AL P          P  P P  H S    L+P   + G  S P H +P 
Sbjct: 240 PVPHTHIQQAPALHP--------QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 291

Query: 266 LHASSPTALRPCLFTHGP-SSMPLHPRPF 293
           LH   P    P     GP    P  P+PF
Sbjct: 292 LHGQGPPG--PHSLQAGPLLQHPGPPQPF 318


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 85/303 (28%), Positives = 101/303 (33%), Gaps = 49/303 (16%)

Query: 52   PRLFTHGP--SSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPC 109
            P+L T GP  S+TA+ P     GS   S  P     +    P  P P  H     AL P 
Sbjct: 759  PQLPTPGPTPSATAVPP----QGSPTASQAP-----NQPQAPTAPVPHTHIQQAPALHP- 808

Query: 110  LFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTH 169
                     P  P P  H S    L P   + G  S P H +P LH   P    P     
Sbjct: 809  -------QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG--PHSLQA 859

Query: 170  GP-SSMPLHPRPF------VHASSPTALRP-CLFTHGPSSMPLHPRPFVHASSP--TALP 219
            GP    P  P+PF          +P    P   + H    +P           P    LP
Sbjct: 860  GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919

Query: 220  PCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF---LHASSPTALRP 276
            P      P +MP H +P      P    P    H P      P PF    +   P AL+P
Sbjct: 920  P-----APLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLS--GPSPFSMNANLPPPPALKP 971

Query: 277  --CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLH--- 331
               L TH P S    P   +  S P    P        S  L P P  H    T LH   
Sbjct: 972  LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--PPTGLHQVA 1029

Query: 332  PRP 334
            P+P
Sbjct: 1030 PQP 1032



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 74/286 (25%), Positives = 87/286 (30%), Gaps = 45/286 (15%)

Query: 38   PWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPL--HPR 95
            P P  H S    L P   + G  S   H  P  HG  P         HS  + PL  HP 
Sbjct: 814  PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG------PHSLQAGPLLQHPG 867

Query: 96   PFVHASSPTALRPCLFTHGPSSMPLHPR---PFVHASSPTALPPCLFTHGPSSMPLHPRP 152
            P      P  L P   + G + +   P    P      P +         P   PL P P
Sbjct: 868  P----PQPFGLPP-QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922

Query: 153  FLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHA 212
                + P   PP       + +P  P P  H   P    P  F+   +  P         
Sbjct: 923  L---AMPHIKPP-----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP--------- 965

Query: 213  SSPTALPP--CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASS 270
              P AL P   L TH P S    P   +  S P    P        S  L P P  H   
Sbjct: 966  --PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--P 1021

Query: 271  PTALRPCLFTHGPSSMPLHPRPFVHASSPTALRP-CLFTHGPSSMP 315
            PT L            P    PFV    P    P C  T  P + P
Sbjct: 1022 PTGLHQV-----APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 1062



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 42/149 (28%), Positives = 46/149 (30%), Gaps = 19/149 (12%)

Query: 154 LHASSPTALPPCLFTHGPSSMPLH--------PRPFVHASSPTALRPCLFTHGPSSMPLH 205
           L A  P    P   T  PSS P          P P   A  P               P  
Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTA 793

Query: 206 PRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF 265
           P P  H     AL P          P  P P  H S    L+P   + G  S P H +P 
Sbjct: 794 PVPHTHIQQAPALHP--------QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 845

Query: 266 LHASSPTALRPCLFTHGP-SSMPLHPRPF 293
           LH   P    P     GP    P  P+PF
Sbjct: 846 LHGQGPPG--PHSLQAGPLLQHPGPPQPF 872


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 85/303 (28%), Positives = 101/303 (33%), Gaps = 49/303 (16%)

Query: 52   PRLFTHGP--SSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPC 109
            P+L T GP  S+TA+ P     GS   S  P     +    P  P P  H     AL P 
Sbjct: 759  PQLPTPGPTPSATAVPP----QGSPTASQAP-----NQPQAPTAPVPHTHIQQAPALHP- 808

Query: 110  LFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTH 169
                     P  P P  H S    L P   + G  S P H +P LH   P    P     
Sbjct: 809  -------QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG--PHSLQA 859

Query: 170  GP-SSMPLHPRPF------VHASSPTALRP-CLFTHGPSSMPLHPRPFVHASSP--TALP 219
            GP    P  P+PF          +P    P   + H    +P           P    LP
Sbjct: 860  GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919

Query: 220  PCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF---LHASSPTALRP 276
            P      P +MP H +P      P    P    H P      P PF    +   P AL+P
Sbjct: 920  P-----APLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLS--GPSPFSMNANLPPPPALKP 971

Query: 277  --CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLH--- 331
               L TH P S    P   +  S P    P        S  L P P  H    T LH   
Sbjct: 972  LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--PPTGLHQVA 1029

Query: 332  PRP 334
            P+P
Sbjct: 1030 PQP 1032



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 74/286 (25%), Positives = 87/286 (30%), Gaps = 45/286 (15%)

Query: 38   PWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPL--HPR 95
            P P  H S    L P   + G  S   H  P  HG  P         HS  + PL  HP 
Sbjct: 814  PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG------PHSLQAGPLLQHPG 867

Query: 96   PFVHASSPTALRPCLFTHGPSSMPLHPR---PFVHASSPTALPPCLFTHGPSSMPLHPRP 152
            P      P  L P   + G + +   P    P      P +         P   PL P P
Sbjct: 868  P----PQPFGLPP-QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922

Query: 153  FLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHA 212
                + P   PP       + +P  P P  H   P    P  F+   +  P         
Sbjct: 923  L---AMPHIKPP-----PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP--------- 965

Query: 213  SSPTALPP--CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASS 270
              P AL P   L TH P S    P   +  S P    P        S  L P P  H   
Sbjct: 966  --PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH--P 1021

Query: 271  PTALRPCLFTHGPSSMPLHPRPFVHASSPTALRP-CLFTHGPSSMP 315
            PT L            P    PFV    P    P C  T  P + P
Sbjct: 1022 PTGLHQV-----APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGP 1062



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 42/149 (28%), Positives = 46/149 (30%), Gaps = 19/149 (12%)

Query: 154 LHASSPTALPPCLFTHGPSSMPLH--------PRPFVHASSPTALRPCLFTHGPSSMPLH 205
           L A  P    P   T  PSS P          P P   A  P               P  
Sbjct: 734 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTA 793

Query: 206 PRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPF 265
           P P  H     AL P          P  P P  H S    L+P   + G  S P H +P 
Sbjct: 794 PVPHTHIQQAPALHP--------QRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP 845

Query: 266 LHASSPTALRPCLFTHGP-SSMPLHPRPF 293
           LH   P    P     GP    P  P+PF
Sbjct: 846 LHGQGPPG--PHSLQAGPLLQHPGPPQPF 872


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 98/347 (28%), Positives = 117/347 (33%), Gaps = 45/347 (12%)

Query: 27  LFPHGSSTALHPWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHG-SSPMSLHPRLFTH 85
           L P  SS    P P    + P    P      PS  A  P   T    SP       F  
Sbjct: 287 LGPLSSSPLATPSP---SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343

Query: 86  SPSSMPLHPRPFVHASSPTALRPCLFTHGP-SSMPLHPRPFVHASSPTAL---------- 134
           SP   PL   P   A    AL P      P +S PL P       +P AL          
Sbjct: 344 SPPLSPLATPP-PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402

Query: 135 -PPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPC 193
            PP      P S P  P     A+ P+  PP L     ++ PL   P   AS P  + P 
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL-----AAPPLQVPPSPPASPP--MSPS 455

Query: 194 LFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHAS--SPTALRPC-- 249
                 +  PL   P   A  P   PP L T    ++P  P  F   +  SP+A  P   
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515

Query: 250 LFTHGPSSMPLHPRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSP---TALRPCL 306
           L T  P + P+   P L         P L    P   P  P P    S P    AL P  
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTL--QAPRRPPT-PGPDTSVSGPRLTLALAP-- 570

Query: 307 FTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKSLHLRLFSHSS 353
              GP      P P   + SST   P    H+SS+ S    L  + S
Sbjct: 571 ---GP------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 75/298 (25%), Positives = 116/298 (38%), Gaps = 48/298 (16%)

Query: 51  HPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCL 110
           HP+L+  G       P     G    S         P+    HP P    ++P ++    
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASS-----VGGPNGGKQHPPP----TTPISVSSSG 266

Query: 111 FTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHP--RPFLHASSPTALPPCLFT 168
            +  P + P    P    + P+A PP  F H   ++P  P  RP  +AS   A PP L  
Sbjct: 267 ASGAPPTKP-PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNAS---ASPPGL-- 320

Query: 169 HGPSSMPLH-PRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGP 227
            G   +P H P P         L P     GP   P        A SP +LPP       
Sbjct: 321 -GAQPLPGHLPSPHAMGQGMGGLPP-----GPEKGP------TLAPSPHSLPPA-----S 363

Query: 228 SSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHA--SSPTALRPCLFTHGPSS 285
           SS P  P  F ++SS ++      +   SS    P P   A  S P +  P      P+S
Sbjct: 364 SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP------PTS 417

Query: 286 MPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKS 343
           + +  +P  + + P+     +++ GP   P    P+    ++++ HP PF  ++ ++S
Sbjct: 418 LSVSNQPPKY-TQPSLPSQAVWSQGPPPPP----PYGRLLANSNAHPGPFPPSTGAQS 470



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 72/273 (26%), Positives = 99/273 (36%), Gaps = 55/273 (20%)

Query: 91  PLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTAL-----PPC--LFTHGP 143
           P HP P      P + +P   T         P P V   +PT       PP   +F   P
Sbjct: 158 PYHPPPLF----PPSPQPPDSTPRQPEASFEPHPSV---TPTGYHAPMEPPTSRMFQAPP 210

Query: 144 SSMPLHPRPFLHASSPTALPPCL---------FTHGPSSMPLHPRPFVHASSPTALRPCL 194
            + P HP+ +   +      P +            GP+    HP P    ++P ++    
Sbjct: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP----TTPISVSSSG 266

Query: 195 FTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHP--RPFVHAS-SPTALRPCLF 251
            +  P + P    P    + P+A PP  F H   ++P  P  RP  +AS SP  L     
Sbjct: 267 ASGAPPTKP-PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL----- 320

Query: 252 THGPSSMPLH-PRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHG 310
             G   +P H P P         L P     GP   P        A SP +L P      
Sbjct: 321 --GAQPLPGHLPSPHAMGQGMGGLPP-----GPEKGP------TLAPSPHSLPPA----- 362

Query: 311 PSSMPLHPRPFVHASSSTSLHPRPFIHASSSKS 343
            SS P  P  F ++SSS+S        +SSS S
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 71/262 (27%), Positives = 95/262 (36%), Gaps = 42/262 (16%)

Query: 112 THGPSSMPLHPRPFVHASSPTALPPCLFTHGP-SSMPLHPRPFLHASSPTALPPC--LFT 168
           + GP+  P HP P      P+  PP      P +S   HP            PP   +F 
Sbjct: 152 SQGPAR-PYHPPPLF---PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQ 207

Query: 169 HGPSSMPLHPRPFVHASSPTALRPCL---------FTHGPSSMPLHPRPF----VHASSP 215
             P + P HP+ +   +      P +            GP+    HP P     V +S  
Sbjct: 208 APPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267

Query: 216 TALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHAS-SPT 272
           +  PP   T  P++      P    + P+A  P  F H   ++P  P  RP  +AS SP 
Sbjct: 268 SGAPP---TKPPTT------PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPP 318

Query: 273 ALRPCLFTHGPSSMPLH-PRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLH 331
            L       G   +P H P P         L P     GP+  P  P     ASSS    
Sbjct: 319 GL-------GAQPLPGHLPSPHAMGQGMGGLPPGP-EKGPTLAP-SPHSLPPASSSAPAP 369

Query: 332 PRPFIHASSSKSLHLRLFSHSS 353
           P  F ++SSS S      S SS
Sbjct: 370 PMRFPYSSSSSSSAAASSSSSS 391



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 68/240 (28%), Positives = 86/240 (35%), Gaps = 40/240 (16%)

Query: 25  QQLFPHGSSTALHPWPFIH---GSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPR 81
           QQ   HG+S    P  F H   G S    HP  +   PS  +L P P      P      
Sbjct: 499 QQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP--YAMSPSLGSLRPYPPGPAHLPPPHSQV 556

Query: 82  LFTHS-PSSMPLHPRPFVHASSPTALRPCLF---THGPSSMP--LHPRPFVHASSPTALP 135
            ++ + P+  P+       +S+     PC     + GP   P    P P V  SS T L 
Sbjct: 557 SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT-LS 615

Query: 136 PCLFTHGPS------SMPLHPRPF-LHASSP----TALPPCLFTHGPSSMPLHPRPFVHA 184
             + T   S      + P  P P+   A SP    TA PP      P S      P    
Sbjct: 616 TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG 675

Query: 185 SSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMP-LHPRPFVHASSP 243
           +SP A        GP +     +P      P  LPP     GPS +P L P P   AS P
Sbjct: 676 TSPPA--------GPGTF----KPGSPTVGPGPLPPA----GPSGLPSLPPPPAAPASGP 719


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 75/298 (25%), Positives = 116/298 (38%), Gaps = 48/298 (16%)

Query: 51  HPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCL 110
           HP+L+  G       P     G    S         P+    HP P    ++P ++    
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASS-----VGGPNGGKQHPPP----TTPISVSSSG 266

Query: 111 FTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHP--RPFLHASSPTALPPCLFT 168
            +  P + P    P    + P+A PP  F H   ++P  P  RP  +AS   A PP L  
Sbjct: 267 ASGAPPTKP-PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNAS---ASPPGL-- 320

Query: 169 HGPSSMPLH-PRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGP 227
            G   +P H P P         L P     GP   P        A SP +LPP       
Sbjct: 321 -GAQPLPGHLPSPHAMGQGMGGLPP-----GPEKGP------TLAPSPHSLPPA-----S 363

Query: 228 SSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHA--SSPTALRPCLFTHGPSS 285
           SS P  P  F ++SS ++      +   SS    P P   A  S P +  P      P+S
Sbjct: 364 SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP------PTS 417

Query: 286 MPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFIHASSSKS 343
           + +  +P  + + P+     +++ GP   P    P+    ++++ HP PF  ++ ++S
Sbjct: 418 LSVSNQPPKY-TQPSLPSQAVWSQGPPPPP----PYGRLLANSNAHPGPFPPSTGAQS 470



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 72/273 (26%), Positives = 99/273 (36%), Gaps = 55/273 (20%)

Query: 91  PLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTAL-----PPC--LFTHGP 143
           P HP P      P + +P   T         P P V   +PT       PP   +F   P
Sbjct: 158 PYHPPPLF----PPSPQPPDSTPRQPEASFEPHPSV---TPTGYHAPMEPPTSRMFQAPP 210

Query: 144 SSMPLHPRPFLHASSPTALPPCL---------FTHGPSSMPLHPRPFVHASSPTALRPCL 194
            + P HP+ +   +      P +            GP+    HP P    ++P ++    
Sbjct: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP----TTPISVSSSG 266

Query: 195 FTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHP--RPFVHAS-SPTALRPCLF 251
            +  P + P    P    + P+A PP  F H   ++P  P  RP  +AS SP  L     
Sbjct: 267 ASGAPPTKP-PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL----- 320

Query: 252 THGPSSMPLH-PRPFLHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHG 310
             G   +P H P P         L P     GP   P        A SP +L P      
Sbjct: 321 --GAQPLPGHLPSPHAMGQGMGGLPP-----GPEKGP------TLAPSPHSLPPA----- 362

Query: 311 PSSMPLHPRPFVHASSSTSLHPRPFIHASSSKS 343
            SS P  P  F ++SSS+S        +SSS S
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 71/262 (27%), Positives = 95/262 (36%), Gaps = 42/262 (16%)

Query: 112 THGPSSMPLHPRPFVHASSPTALPPCLFTHGP-SSMPLHPRPFLHASSPTALPPC--LFT 168
           + GP+  P HP P      P+  PP      P +S   HP            PP   +F 
Sbjct: 152 SQGPAR-PYHPPPLF---PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQ 207

Query: 169 HGPSSMPLHPRPFVHASSPTALRPCL---------FTHGPSSMPLHPRPF----VHASSP 215
             P + P HP+ +   +      P +            GP+    HP P     V +S  
Sbjct: 208 APPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267

Query: 216 TALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHAS-SPT 272
           +  PP   T  P++      P    + P+A  P  F H   ++P  P  RP  +AS SP 
Sbjct: 268 SGAPP---TKPPTT------PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPP 318

Query: 273 ALRPCLFTHGPSSMPLH-PRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLH 331
            L       G   +P H P P         L P     GP+  P  P     ASSS    
Sbjct: 319 GL-------GAQPLPGHLPSPHAMGQGMGGLPPGP-EKGPTLAP-SPHSLPPASSSAPAP 369

Query: 332 PRPFIHASSSKSLHLRLFSHSS 353
           P  F ++SSS S      S SS
Sbjct: 370 PMRFPYSSSSSSSAAASSSSSS 391



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 68/240 (28%), Positives = 86/240 (35%), Gaps = 40/240 (16%)

Query: 25  QQLFPHGSSTALHPWPFIH---GSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPR 81
           QQ   HG+S    P  F H   G S    HP  +   PS  +L P P      P      
Sbjct: 499 QQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP--YAMSPSLGSLRPYPPGPAHLPPPHSQV 556

Query: 82  LFTHS-PSSMPLHPRPFVHASSPTALRPCLF---THGPSSMP--LHPRPFVHASSPTALP 135
            ++ + P+  P+       +S+     PC     + GP   P    P P V  SS T L 
Sbjct: 557 SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT-LS 615

Query: 136 PCLFTHGPS------SMPLHPRPF-LHASSP----TALPPCLFTHGPSSMPLHPRPFVHA 184
             + T   S      + P  P P+   A SP    TA PP      P S      P    
Sbjct: 616 TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG 675

Query: 185 SSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMP-LHPRPFVHASSP 243
           +SP A        GP +     +P      P  LPP     GPS +P L P P   AS P
Sbjct: 676 TSPPA--------GPGTF----KPGSPTVGPGPLPPA----GPSGLPSLPPPPAAPASGP 719


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 78/314 (24%), Positives = 111/314 (35%), Gaps = 34/314 (10%)

Query: 45  SSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPT 104
           +SP   H  +   GP+ T L P      S+  +L P L   S       PRP   A+ P+
Sbjct: 303 TSPTNPHQHMAVGGPAQTPLLPAKL---SASNALDPML-PASVGGSTRTPRPA--AAQPS 356

Query: 105 ALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHASSPTALPP 164
             +    T  P S+P  P     +  P   P       PSS      P      PT+ P 
Sbjct: 357 --QKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPV 414

Query: 165 CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPL------HPRPFVHASSPTAL 218
                 P+  P+   P +    P + RP   T   S  P+        +   HAS P + 
Sbjct: 415 PARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASA 474

Query: 219 PPCLFTHGP------SSMPLHPRPFVHASSP--TALRPCLFTHGPSSMPLHPRPFLHASS 270
                TH P      SS P        ++ P  T + P   T  P + P  P P    S+
Sbjct: 475 RTS--THKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTP---GSA 529

Query: 271 PTALRPCLFTH-----GPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHAS 325
           PT  +  + +      GP S P  P P     +   +     T  PS  P  P+P    +
Sbjct: 530 PTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPS--PRQPQPSQQTT 587

Query: 326 SSTSLHPRPFIHAS 339
            +  L P  F+ +S
Sbjct: 588 PALVLAPAQFLSSS 601


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 68/314 (21%), Positives = 114/314 (36%), Gaps = 17/314 (5%)

Query: 40   PFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVH 99
            P     SP    P+  ++ P+S +  P   ++  +  +  P   ++SP+S    P    +
Sbjct: 1598 PAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSY 1657

Query: 100  ASSPTALRPCLFTHGPSSMPLHPR-PFVHASSPTALP--PCLFTHGPSSMPLHPR----- 151
            + +  +  P   ++ P+S    P  P    +SP+  P  P      PS  P  P      
Sbjct: 1658 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1717

Query: 152  PFLHASSPTALP--PCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPR-- 207
            P    +SP+  P  P      PS  P  P     + + T   P      PS  P  P   
Sbjct: 1718 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYT 1777

Query: 208  PFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLH 267
            P     SPT+  P      PS  P  P    ++ S     P   T+ PSS    P    +
Sbjct: 1778 PTSPNYSPTS--PSYSPTSPSYSPTSPS---YSPSSPRYTPQSPTYTPSSPSYSPSSPSY 1832

Query: 268  ASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSS 327
            + +     P   ++ PSS    P    ++ +     P    + P+S    P    ++ +S
Sbjct: 1833 SPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTS 1892

Query: 328  TSLHPRPFIHASSS 341
             +  P   ++  +S
Sbjct: 1893 PTYSPTSPVYTPTS 1906



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 72/290 (24%), Positives = 107/290 (36%), Gaps = 28/290 (9%)

Query: 57   HGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGPS 116
            + P+S +  P   ++  +  S  P   ++SP+S    P    ++ +  +  P   ++ P+
Sbjct: 1636 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1695

Query: 117  SMPLHP-RPFVHASSPTALP--PCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSS 173
            S    P  P    +SP+  P  P      PS  P  P     + SPT+  P      P+ 
Sbjct: 1696 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-----SYSPTS--PSYSPTSPNY 1748

Query: 174  MPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHPR--PFVHASSPTALPPCLFTHGPSS 229
             P  P   P   + SPT+  P      P+  P  P   P   + SPT+  P      PS 
Sbjct: 1749 SPTSPNYTPTSPSYSPTS--PSYSPTSPNYTPTSPNYSPTSPSYSPTS--PSYSPTSPSY 1804

Query: 230  MPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPR-----PFLHASSP--TALRPCLFTHG 282
             P  PR    + + T   P      PS  P  P+     P    SSP  T   P      
Sbjct: 1805 SPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTS 1864

Query: 283  PSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHP 332
            P   P  P+     +SPT   P    + P+S    P   V+  +S    P
Sbjct: 1865 PKYSPTSPK--YSPTSPT-YSPTTPKYSPTSPTYSPTSPVYTPTSPKYSP 1911



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 73/308 (23%), Positives = 116/308 (37%), Gaps = 28/308 (9%)

Query: 56   THGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGP 115
            ++ P+S +  P   ++  +  S  P   ++SP+S    P    ++ +  +  P   ++ P
Sbjct: 1663 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1722

Query: 116  SSMPLHP-RPFVHASSPTALPPCLFTHGPSSMPLHPR--PFLHASSPTALPPCLFTHGPS 172
            +S    P  P    +SP+  P       P+  P  P   P   + SPT+  P      P+
Sbjct: 1723 TSPSYSPTSPSYSPTSPSYSPT-----SPNYSPTSPNYTPTSPSYSPTS--PSYSPTSPN 1775

Query: 173  SMPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSM 230
              P  P   P   + SPT+  P      PS  P  PR    + + T   P      PS  
Sbjct: 1776 YTPTSPNYSPTSPSYSPTS--PSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYS 1833

Query: 231  PLHPR-----PFVHASSP--TALRPCLFTHGPSSMPLHPR--PFLHASSPTALR--PCLF 279
            P  P+     P    SSP  T   P      P   P  P+  P     SPT  +  P   
Sbjct: 1834 PTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSP 1893

Query: 280  THGPSSMPLHP-RPFVHASSPT--ALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFI 336
            T+ P+S    P  P    +SPT     P      P+  P  P+   ++ +S    P    
Sbjct: 1894 TYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPT 1953

Query: 337  HASSSKSL 344
            ++ +S ++
Sbjct: 1954 YSLTSPAI 1961



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 66/289 (22%), Positives = 107/289 (37%), Gaps = 17/289 (5%)

Query: 56   THGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLFTHGP 115
            ++ P+S +  P   ++  +  S  P   ++SP+S    P    ++ +  +  P   ++ P
Sbjct: 1649 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1708

Query: 116  SSMPLHPR-PFVHASSPTALP--PCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPS 172
            +S    P  P    +SP+  P  P      PS  P  P     + + T   P      PS
Sbjct: 1709 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPS 1768

Query: 173  SMPLHPR--PFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSM 230
              P  P   P     SPT+  P      PS  P  P    ++ S     P   T+ PSS 
Sbjct: 1769 YSPTSPNYTPTSPNYSPTS--PSYSPTSPSYSPTSPS---YSPSSPRYTPQSPTYTPSSP 1823

Query: 231  PLHP-RPFVHASSP--TALRPCLFTHGPSSMPLHPR--PFLHASSPTALR--PCLFTHGP 283
               P  P    +SP  T   P      P   P  P+  P     SPT+ +  P   T+ P
Sbjct: 1824 SYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSP 1883

Query: 284  SSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHP 332
            ++    P    ++ +     P    + P+S    P    ++ +S +  P
Sbjct: 1884 TTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSP 1932



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 81/325 (24%), Positives = 124/325 (38%), Gaps = 32/325 (9%)

Query: 31   GSSTALHPWPFIHGSSPM--ALHPRLFTH-GPSSTALHPCPFTHGSSPMSLHPRLFTHSP 87
            G S A+ PW    G++P   A  P + +   P +    P   +  S     +   ++ +P
Sbjct: 1512 GISPAMTPWN--QGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTP 1569

Query: 88   SS--MPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHAS---SPTALPPCLFTHG 142
             S   P    P++  S   A+ P      P+  P  P  +   S   SPT+  P      
Sbjct: 1570 GSPGSPGPSSPYI-PSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTS--PSYSPTS 1626

Query: 143  PSSMPLHPR--PFLHASSPTA--LPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHG 198
            PS  P  P   P   + SPT+    P   ++ P+S    P    ++ +  +  P   ++ 
Sbjct: 1627 PSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1686

Query: 199  PSSMPLHP-RPFVHASSPTALP--PCLFTHGPSSMPLHP--RPFVHASSPTALRPCLFTH 253
            P+S    P  P    +SP+  P  P      PS  P  P   P   + SPT+  P     
Sbjct: 1687 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS--PSYSPT 1744

Query: 254  GPSSMPLHPR--PFLHASSPTALRPCLFTHGPSSMPLHPR--PFVHASSPT--ALRPCLF 307
             P+  P  P   P   + SPT+  P      P+  P  P   P   + SPT  +  P   
Sbjct: 1745 SPNYSPTSPNYTPTSPSYSPTS--PSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP 1802

Query: 308  THGPSSMPLHPRPFVHASSSTSLHP 332
            ++ PSS    P+   +  SS S  P
Sbjct: 1803 SYSPSSPRYTPQSPTYTPSSPSYSP 1827



 Score = 32.3 bits (72), Expect = 0.75
 Identities = 37/151 (24%), Positives = 58/151 (38%), Gaps = 10/151 (6%)

Query: 52   PRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPFVHASSPTALRPCLF 111
            P+  T+ PSS +  P   ++  +     P   ++SPSS    P    ++ +     P   
Sbjct: 1813 PQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSP 1872

Query: 112  THGPSSMPLHP-RPFVHASSPTALP--PCLFTHGPSSMPLHP-----RPFLHASSPTALP 163
             + P+S    P  P    +SPT  P  P      P   P  P      P    +SPT  P
Sbjct: 1873 KYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSP 1932

Query: 164  --PCLFTHGPSSMPLHPRPFVHASSPTALRP 192
              P   T+ P+S    P    ++ +  A+ P
Sbjct: 1933 TSPKGSTYSPTSPGYSPTSPTYSLTSPAISP 1963



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 36/187 (19%), Positives = 74/187 (39%), Gaps = 5/187 (2%)

Query: 158  SPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPR-PFVHASSPT 216
            SP   P    T G    P    P++  S   A+ P   ++ P+S    PR P  +     
Sbjct: 1558 SPGYSPAWSPTPGSPGSPGPSSPYI-PSPGGAMSP---SYSPTSPAYEPRSPGGYTPQSP 1613

Query: 217  ALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRP 276
            +  P   ++ P+S    P    ++ +  +  P   ++ P+S    P    ++ +  +  P
Sbjct: 1614 SYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1673

Query: 277  CLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHPRPFI 336
               ++ P+S    P    ++ +  +  P   ++ P+S    P    ++ +S S  P    
Sbjct: 1674 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1733

Query: 337  HASSSKS 343
            ++ +S S
Sbjct: 1734 YSPTSPS 1740


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 66/262 (25%), Positives = 92/262 (35%), Gaps = 57/262 (21%)

Query: 38  PWPFIHGSSPMALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSMPLHPRPF 97
           P P +HG+      P   +         P     G +P+ + P        + P  P P 
Sbjct: 280 PPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP--------TPPPPPPPL 331

Query: 98  VHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFLHAS 157
             A S ++LR  + +  P  +P  P P   A    A+PP      P+ + + P   LH +
Sbjct: 332 PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPP-----PPAPLQIAP-GVLHPA 385

Query: 158 SPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTA 217
            P   PP           + P P V  ++P             ++P+HP P         
Sbjct: 386 PPPIAPPL----------VQPSPPVARAAPVC----------ETVPVHPLP---QGEVQG 422

Query: 218 LPPCLFTHGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPC 277
           LPP      P   P  P P +  SSP  +      H PS   LHP P       TA  P 
Sbjct: 423 LPP------PPPPPPLPPPGIRPSSPVTV--TALAHPPSG--LHPTP------STAPGP- 465

Query: 278 LFTHGPSSMPLHPRPFVHASSP 299
              H P   P  P   + AS P
Sbjct: 466 ---HVPLMPPSPPSQVIPASEP 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,884,504
Number of Sequences: 37866
Number of extensions: 1609745
Number of successful extensions: 8886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 349
Number of HSP's that attempted gapping in prelim test: 6043
Number of HSP's gapped (non-prelim): 1576
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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