Guide to the Human Genome
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Search of human proteins with 38348366

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38348366 suprabasin [Homo sapiens]
         (247 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38348366 suprabasin [Homo sapiens]                                 497   e-141
gi|57864582 hornerin [Homo sapiens]                                    49   5e-06
gi|60097902 filaggrin [Homo sapiens]                                   40   0.002
gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Ho...    40   0.002
gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a ...    40   0.002
gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b...    40   0.002
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    39   0.003
gi|171916097 repetin [Homo sapiens]                                    39   0.004
gi|186928825 dermokine isoform 3 precursor [Homo sapiens]              38   0.009
gi|239746652 PREDICTED: hypothetical protein [Homo sapiens]            37   0.021
gi|62122917 filaggrin family member 2 [Homo sapiens]                   36   0.035
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                   33   0.18 
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      33   0.23 
gi|18702331 OTU domain containing 7A [Homo sapiens]                    33   0.23 
gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [H...    33   0.30 
gi|169216749 PREDICTED: similar to Putative paraneoplastic antig...    33   0.30 
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    32   0.39 
gi|19923838 solute carrier family 13 (sodium/sulfate symporters)...    32   0.67 
gi|16262452 cingulin [Homo sapiens]                                    32   0.67 
gi|186928829 dermokine isoform 4 precursor [Homo sapiens]              31   0.87 
gi|186928827 dermokine isoform 5 precursor [Homo sapiens]              31   0.87 
gi|33504489 dermokine isoform 2 precursor [Homo sapiens]               31   0.87 
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         31   0.87 
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   31   1.1  
gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]             31   1.1  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     30   1.5  
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...    30   1.5  
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ...    30   1.5  
gi|119220598 apolipoprotein B48 receptor [Homo sapiens]                30   1.5  
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                    30   1.9  

>gi|38348366 suprabasin [Homo sapiens]
          Length = 247

 Score =  497 bits (1279), Expect = e-141
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 1   MHLARLVGSCSLLLLLGALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITH 60
           MHLARLVGSCSLLLLLGALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITH
Sbjct: 1   MHLARLVGSCSLLLLLGALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITH 60

Query: 61  AGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVN 120
           AGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVN
Sbjct: 61  AGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVN 120

Query: 121 NAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQA 180
           NAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQA
Sbjct: 121 NAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQA 180

Query: 181 GKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGASVNTPFINLPALWR 240
           GKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGASVNTPFINLPALWR
Sbjct: 181 GKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGASVNTPFINLPALWR 240

Query: 241 SVANIMP 247
           SVANIMP
Sbjct: 241 SVANIMP 247


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 46/206 (22%), Positives = 75/206 (36%), Gaps = 9/206 (4%)

Query: 17   GALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMG 76
            G+ SGW++S  P E    G + GL + E   G++      G +             S   
Sbjct: 2438 GSGSGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 2496

Query: 77   SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGK-EAEKLGHGVNNAAGQA----GKEAD 131
            S  G+      Q  +HG        + G G+ G    +  GHG   +  +     G+   
Sbjct: 2497 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556

Query: 132  KAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAG--QAGKELQNAHN 189
             + +   +G H +G   E  G G + ++        + G G+ H++G  Q G     +  
Sbjct: 2557 GSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2615

Query: 190  GVNQASKEANQLLNGNHQSGSSSHQG 215
            G    S   +    G H SGS    G
Sbjct: 2616 GERHGSSSGSSSHYGQHGSGSRQSSG 2641



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 46/206 (22%), Positives = 74/206 (35%), Gaps = 9/206 (4%)

Query: 17   GALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMG 76
            G+ SGW++S  P E    G + GL + E   G++      G +             S   
Sbjct: 1968 GSGSGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQS 2026

Query: 77   SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGK-EAEKLGHGVNNAAGQA----GKEAD 131
            S  G+      Q  +HG        + G G+ G    +  GHG   +  +     G+   
Sbjct: 2027 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2086

Query: 132  KAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAG--QAGKELQNAHN 189
             + +   +G H  G   E  G G + ++        + G G+ H++G  Q G     +  
Sbjct: 2087 GSGRSSSSGQHGPGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2145

Query: 190  GVNQASKEANQLLNGNHQSGSSSHQG 215
            G    S   +    G H SGS    G
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGSRQSSG 2171



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/203 (22%), Positives = 73/203 (35%), Gaps = 9/203 (4%)

Query: 20   SGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHT 79
            SGW++S  P E    G + GL + E   G++      G +             S   S  
Sbjct: 1031 SGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1089

Query: 80   GKELDKGVQGLNHGMDKVAHEINHGIGQAGK-EAEKLGHGVNNAAGQA----GKEADKAV 134
            G+      Q  +HG        + G G+ G    +  GHG   +  +     G+    + 
Sbjct: 1090 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG 1149

Query: 135  QGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAG--QAGKELQNAHNGVN 192
            +   +G H +G   E  G G + ++        + G G+ H++G  Q G     +  G  
Sbjct: 1150 RSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208

Query: 193  QASKEANQLLNGNHQSGSSSHQG 215
              S   +    G H SGS    G
Sbjct: 1209 HGSSSGSSSHYGQHGSGSRQSSG 1231



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 45/206 (21%), Positives = 74/206 (35%), Gaps = 9/206 (4%)

Query: 17   GALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMG 76
            G+ SGW++S  P E      + GL + E   G++      G +             S   
Sbjct: 1498 GSGSGWSSSRGPYESG-SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556

Query: 77   SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGK-EAEKLGHGVNNAAGQA----GKEAD 131
            S  G+      Q  +HG        + G G+ G    +  GHG   +  +     G+   
Sbjct: 1557 SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 1616

Query: 132  KAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAG--QAGKELQNAHN 189
             + +   +G H +G   E  G G + ++        + G G+ H++G  Q G     +  
Sbjct: 1617 GSGRSSSSGQHGSGL-GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1675

Query: 190  GVNQASKEANQLLNGNHQSGSSSHQG 215
            G    S   +    G H SGS    G
Sbjct: 1676 GERHGSSSRSSSRYGQHGSGSRQSSG 1701



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 44/203 (21%), Positives = 77/203 (37%), Gaps = 18/203 (8%)

Query: 35  GINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGM 94
           G  +  S + +  G +  G  SG  H+  + +      S   S +G+      Q  ++G 
Sbjct: 347 GFGQHESGSGQSSGYSKHGSGSG--HSSSQGQH--GSTSGQASSSGQHGSSSRQSSSYGQ 402

Query: 95  DKVAHEINHGIGQ-AGKEAEKLGHGVNNAAGQAGKEADKAVQGF----HTGVHQAGKEAE 149
            + A   + G GQ +    +  GHG   +       + +   GF     +G + +G    
Sbjct: 403 HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS 462

Query: 150 KLGQGVNHAADQAGKEVEKLGQGAHHAAG--QAGKELQNAHNGVNQASKEANQLLNGNHQ 207
             G G + ++ +      + G G+ H++G  Q G     +  G  Q S   +    G H 
Sbjct: 463 S-GFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHG 521

Query: 208 SGS------SSHQGGATTTPLAS 224
           SGS      S H  G+  +P  S
Sbjct: 522 SGSRQSLGHSRHGSGSGQSPSPS 544



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 47/211 (22%), Positives = 74/211 (35%), Gaps = 15/211 (7%)

Query: 20  SGWAASDDPIEKVIEGINRGLSNAEREVGKALD----GINSGITHAGREVEKVFNGLSNM 75
           SG ++S  P E    G + GL + E   G++      G +SG +    +        S+ 
Sbjct: 565 SGRSSSRGPYESG-SGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623

Query: 76  GSH---TGKELDKGVQGLNHGMDKVAHEINHGIGQA---GKEAEKLGHGVNNAAGQAGKE 129
           G H   +G+    G  G          +   G GQ+   G+     GH  +++ GQ G  
Sbjct: 624 GQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH--SSSYGQHGSG 681

Query: 130 AD-KAVQGFHTGVH-QAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNA 187
           +   +  G H  V  Q+     K G G +    Q G           H +          
Sbjct: 682 SGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741

Query: 188 HNGVNQASKEANQLLNGNHQSGSSSHQGGAT 218
           H   +  S    Q  +G+HQS     QG  +
Sbjct: 742 HGSSSGLSSSYGQHGSGSHQSSGHGRQGSGS 772



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 36/152 (23%), Positives = 52/152 (34%), Gaps = 14/152 (9%)

Query: 76  GSHTGKELDKGVQGLNHGMDKVAHEINHGIGQA---GKEAEKLGHGVN---NAAGQ---A 126
           GS +G     G  G              G GQA   G+     G G +   +A+G     
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQ 841

Query: 127 GKEADKAVQGFHTGVHQAGK-EAEKLGQ--GVNHAADQAGKEVEKLGQGAHHAAGQAGKE 183
           G+    + Q   +G H +   ++   GQ    +H A   G+     GQ   H  GQ G  
Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGH--GQRGSG 899

Query: 184 LQNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
              + +     S       +G H SGS    G
Sbjct: 900 SGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG 931



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 33/151 (21%), Positives = 49/151 (32%), Gaps = 9/151 (5%)

Query: 66  EKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQ 125
           E +   LS     +G+      Q  ++G        + G GQ G      G G +   GQ
Sbjct: 153 ESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGS-----GSGQSPNYGQ 207

Query: 126 AGKEADKAVQGFHTGVHQAGK-EAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKEL 184
            G  +    Q      H +G  ++    Q  + +   +G      G G     GQ G   
Sbjct: 208 HGSGSG---QSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRS 264

Query: 185 QNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
             +  G    S   +    G H SGS    G
Sbjct: 265 GQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 20/164 (12%)

Query: 76  GSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAV- 134
           G+ TG     G QG +H  ++      H   Q G++  + GH  ++  G+ G   +++V 
Sbjct: 486 GTSTG-----GRQGSHH--EQARDSSRHSASQEGQDTIR-GHPGSSRGGRQGSHHEQSVN 537

Query: 135 QGFHTGVHQA-----GKEAEKLGQGVNHAADQAGKEVEKLGQGA------HHAAGQAGKE 183
           +  H+G H +     G+     GQ  + +A +  +  E+ G G       HH A      
Sbjct: 538 RSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADS 597

Query: 184 LQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
            +++  G  Q+S        G+  S  S  QG +  +   SG++
Sbjct: 598 SRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 641



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 33/152 (21%), Positives = 66/152 (43%), Gaps = 15/152 (9%)

Query: 88   QGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAV-QGFHTGVHQA-- 144
            QG +H  ++      H   Q G++  + GH  ++  G+ G   +++V +  H+G H +  
Sbjct: 3411 QGSHH--EQARDSSRHSASQEGQDTIR-GHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHT 3467

Query: 145  ---GKEAEKLGQGVNHAADQAGKEVEKLGQGA------HHAAGQAGKELQNAHNGVNQAS 195
               G+     GQ  + +A +  +  E+ G G+      HH A       +++ +G  Q++
Sbjct: 3468 TSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSA 3527

Query: 196  KEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
                    G+  S  S  QG +  +   SG++
Sbjct: 3528 GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 3559



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 37/200 (18%), Positives = 73/200 (36%), Gaps = 8/200 (4%)

Query: 34   EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLN-- 91
            E  +RG + +  E  ++  G   G  H  +  +   +     G  +    D G +G +  
Sbjct: 1983 ESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGS 2042

Query: 92   HGMDKVAHEIN---HGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQG-FHTGVHQAGKE 147
               D   H  +     +   GK          +A GQ+G+ + ++    +    H+  + 
Sbjct: 2043 QASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSES 2102

Query: 148  AEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQ 207
                GQ       + G   ++    + H+A Q G++    H G ++  ++ +       +
Sbjct: 2103 TH--GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDR 2160

Query: 208  SGSSSHQGGATTTPLASGAS 227
            SG S      TT+   S AS
Sbjct: 2161 SGHSGSHHSHTTSQGRSDAS 2180



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 19/183 (10%)

Query: 43   AEREVGKALDGINSGITHAGREVEKVFNGLSNMGSH--TGKELDKGVQGLNHGMDKVAHE 100
            + +E  +   G  SG  H+G  + +V     +  SH  TG    +G QG  H  ++    
Sbjct: 2719 SHQESARGRSGETSG--HSGSFLYQVSTHEQSESSHGWTGPST-RGRQGSRH--EQAQDS 2773

Query: 101  INHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF-HTGVHQA-----GKEAEKLGQG 154
              H   Q G++  + GH  ++  G+ G   + +V    H+G H +     G+     GQ 
Sbjct: 2774 SRHSASQDGQDTIR-GHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS 2832

Query: 155  VNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQS---GSS 211
             + +A +  +  E+ G G+ H+  +  +   + H  +++ S+       G+ +S   GSS
Sbjct: 2833 GSRSASRTTRNEEQSGDGSRHSGSRHHE--ASTHADISRHSQAVQGQSEGSRRSRRQGSS 2890

Query: 212  SHQ 214
              Q
Sbjct: 2891 VSQ 2893



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 38/202 (18%), Positives = 75/202 (37%), Gaps = 13/202 (6%)

Query: 34  EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLN-- 91
           E  +RG + +  E  ++  G   G  H  +  +   +  +  G  +    D+G +G +  
Sbjct: 362 ETSSRGQTASSHEQARSSPGERHGSGHQ-QSADSSRHSATGRGQASSAVSDRGHRGSSGS 420

Query: 92  HGMDKVAHEINH------GIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAG 145
              D   H  N       G G+AG   +         +G+    +  ++  +    H+  
Sbjct: 421 QASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSL--YQVSTHEQP 478

Query: 146 KEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGN 205
             A   G+       + G   E+    + H+A Q G++    H G ++  ++ +      
Sbjct: 479 DSAH--GRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSV 536

Query: 206 HQSGSSSHQGGATTTPLASGAS 227
           ++SG S      TT+   S AS
Sbjct: 537 NRSGHSGSHHSHTTSQGRSDAS 558



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 34/154 (22%), Positives = 65/154 (42%), Gaps = 15/154 (9%)

Query: 86   GVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAV-QGFHTGVHQA 144
            G QG ++  D+      H   Q G++  + GH   +  G+ G   +++V +  H+G H +
Sbjct: 2113 GRQGSHY--DQAQDSSRHSASQEGQDTIR-GHPGPSRGGRQGSHQEQSVDRSGHSGSHHS 2169

Query: 145  -----GKEAEKLGQGVNHAADQAGKEVEKLGQGA------HHAAGQAGKELQNAHNGVNQ 193
                 G+     GQ  + +A +   + E+ G G+      HH A       +++  G  Q
Sbjct: 2170 HTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ 2229

Query: 194  ASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
            +S        G+  S  S  +G +  +   SG++
Sbjct: 2230 SSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSA 2263



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 35/168 (20%), Positives = 65/168 (38%), Gaps = 6/168 (3%)

Query: 60   HAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGV 119
            H+G    +  + + + G H G    +      H  D     ++   GQAG   +      
Sbjct: 1370 HSGIGHRQASSAVRDSG-HRGSSGSQVTNSEGHSEDSDTQSVS-AHGQAGPHQQS---HK 1424

Query: 120  NNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQ 179
             +A GQ+G+ + ++ + F   V    +     GQ       + G   E+    + H+A Q
Sbjct: 1425 ESARGQSGESSGRS-RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQ 1483

Query: 180  AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             G++    H G ++  ++ +       +SG S +    TT    S AS
Sbjct: 1484 DGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDAS 1531



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 30/150 (20%), Positives = 52/150 (34%), Gaps = 5/150 (3%)

Query: 78   HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
            H G    +      H  D     ++   GQAG   +   H  +     AG+        +
Sbjct: 3656 HRGSSGSQASDSEGHSEDSDTQSVS-AHGQAGPHQQS--HQESTRGRSAGRSGRSGSFLY 3712

Query: 138  HTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKE 197
                H+  + A   G+       + G   E+    + H+A Q G++    H G  +  ++
Sbjct: 3713 QVSTHEQSESAH--GRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770

Query: 198  ANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             +       +SG S      TT+   S AS
Sbjct: 3771 GSYHEQSVDRSGHSGSHHSHTTSQGRSDAS 3800



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 31/168 (18%), Positives = 63/168 (37%), Gaps = 6/168 (3%)

Query: 60  HAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGV 119
           H+G    +  + + + G H G    +      H  D     ++ G GQAG   +      
Sbjct: 722 HSGTGHGQASSAVRDSG-HRGSSGSQATDSEGHSEDSDTQSVS-GHGQAGHHQQSHQESA 779

Query: 120 NNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQ 179
            + +G+  + +   +  +    H+  + +   G        + G   E+    + H+A Q
Sbjct: 780 RDRSGERSRRSGSFL--YQVSTHKQSESSH--GWTGPSTGVRQGSHHEQARDNSRHSASQ 835

Query: 180 AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
            G++    H G ++  ++ +       +SG S      TT+   S AS
Sbjct: 836 DGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 883



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 34/155 (21%), Positives = 57/155 (36%), Gaps = 19/155 (12%)

Query: 73   SNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADK 132
            S    + G   D   Q ++      +H+ +H     G+  E  GH  +     +  E  +
Sbjct: 2690 SQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSE 2749

Query: 133  AVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVN 192
            +  G+ TG    G+      QG  H         E+    + H+A Q G++    H G  
Sbjct: 2750 SSHGW-TGPSTRGR------QGSRH---------EQAQDSSRHSASQDGQDTIRGHPG-- 2791

Query: 193  QASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             +S+   Q  +  H   SS H G   +   + G S
Sbjct: 2792 -SSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 2825



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 34/155 (21%), Positives = 57/155 (36%), Gaps = 19/155 (12%)

Query: 73   SNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADK 132
            S    + G   D   Q ++      +H+ +H     G+  E  GH  +     +  E  +
Sbjct: 3014 SQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSE 3073

Query: 133  AVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVN 192
            +  G+ TG    G+      QG  H         E+    + H+A Q G++    H G  
Sbjct: 3074 SSHGW-TGPSTRGR------QGSRH---------EQAQDSSRHSASQYGQDTIRGHPG-- 3115

Query: 193  QASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             +S+   Q  +  H   SS H G   +   + G S
Sbjct: 3116 -SSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 29/150 (19%), Positives = 54/150 (36%), Gaps = 5/150 (3%)

Query: 78   HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
            H G    +      H  +     ++ G GQAG   +       + +G  G+        +
Sbjct: 3332 HWGSSGSQASDSEGHSEESDTQSVS-GHGQAGPHQQSHQESARDRSG--GRSGRSGSFLY 3388

Query: 138  HTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKE 197
                H+  + A   G+       + G   E+    + H+A Q G++    H G ++  ++
Sbjct: 3389 QVSTHEQSESAH--GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446

Query: 198  ANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             +       +SG S      TT+   S AS
Sbjct: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDAS 3476



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 29/141 (20%), Positives = 58/141 (41%), Gaps = 15/141 (10%)

Query: 86   GVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAV-QGFHTGVHQA 144
            G QG  H  ++      H   Q G++  + GH  +   G+ G   +++V +  H+G H +
Sbjct: 3733 GRQGSRH--EQARDSSRHSASQEGQDTIR-GHPGSRRGGRQGSYHEQSVDRSGHSGSHHS 3789

Query: 145  -----GKEAEKLGQGVNHAADQAGKEVEKLGQGA------HHAAGQAGKELQNAHNGVNQ 193
                 G+     GQ  + +A +  +  E+ G G+      HH A       +++ +G  +
Sbjct: 3790 HTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE 3849

Query: 194  ASKEANQLLNGNHQSGSSSHQ 214
            ++        G+  S  S  +
Sbjct: 3850 SAGSRRSRRQGSSVSQDSDSE 3870



 Score = 32.7 bits (73), Expect = 0.30
 Identities = 27/122 (22%), Positives = 48/122 (39%), Gaps = 12/122 (9%)

Query: 116  GHGVNNAAGQAGKEADKAVQGFHTG----------VHQAGKEAEKLGQGVNHAADQAGKE 165
            GHG +    Q+ +E+ +   G  +G           H+  + A   G+       + G  
Sbjct: 1088 GHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAH--GRTRTSTGRRQGSH 1145

Query: 166  VEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASG 225
             E+    + H+A Q G++   AH G  +  ++ +       +SG S      TT+   S 
Sbjct: 1146 HEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSD 1205

Query: 226  AS 227
            AS
Sbjct: 1206 AS 1207



 Score = 32.0 bits (71), Expect = 0.51
 Identities = 42/176 (23%), Positives = 71/176 (40%), Gaps = 26/176 (14%)

Query: 76   GSHTGKELDKGVQ-GLNHGMDKVAHEINHGIGQAGKEA-EKLGHGVNN------AAGQAG 127
            GSH  +  D     G+ HG    A   +   G +G +A +  GH  ++      A GQAG
Sbjct: 2331 GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAG 2390

Query: 128  ---KEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQA--GKEVEKLG--QGAHH----- 175
               +   ++ +G   G  ++G+    L Q   H   ++  G+     G  QG+HH     
Sbjct: 2391 PHQQSHQESTRGRSAG--RSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARD 2448

Query: 176  ----AAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
                +  Q G++  + H G +   ++ +       +SG S      TT+   S AS
Sbjct: 2449 SSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDAS 2504



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 35/148 (23%), Positives = 53/148 (35%), Gaps = 19/148 (12%)

Query: 77  SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLG--HGVNNAAGQAGKEADKAV 134
           +H G   ++   G  H   +  HE   G G +   + K G  H  N+++GQA    ++A 
Sbjct: 644 NHHGSAQEQSRDGSRH--PRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQAR 701

Query: 135 QGF---HTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
                 H   HQ          G  H   QA   V          +G  G     A +  
Sbjct: 702 SSAGERHGSRHQLQSADSSRHSGTGHG--QASSAVRD--------SGHRGSSGSQATDSE 751

Query: 192 NQASKEANQLLNGNHQSG--SSSHQGGA 217
             +     Q ++G+ Q+G    SHQ  A
Sbjct: 752 GHSEDSDTQSVSGHGQAGHHQQSHQESA 779



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 33/167 (19%), Positives = 57/167 (34%), Gaps = 14/167 (8%)

Query: 73   SNMGSHTGKELDKGVQGL--NHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEA 130
            S+  S TG+  D  V G   N G        + G  +         HG      Q+ +E+
Sbjct: 1691 SSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQES 1750

Query: 131  DKAVQGFHTG----------VHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQA 180
             +   G  +G           H+  + A   G+       +     E+    + H+A Q 
Sbjct: 1751 TRGQSGERSGRSGSFLYQVSTHEQSESAH--GRTGPSTGGRQRSRHEQARDSSRHSASQE 1808

Query: 181  GKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
            G++    H G ++  ++ +        SG S      TT+   S  S
Sbjct: 1809 GQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVS 1855



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 32/155 (20%), Positives = 55/155 (35%), Gaps = 16/155 (10%)

Query: 77   SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLG--HGVNNAAGQAGK--EADK 132
            +H G   ++   G  H   +  HE   G G + + + + G  H  N++ GQA    E  +
Sbjct: 2266 NHHGSAQEQSRDGSRH--PRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR 2323

Query: 133  AVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVN 192
            +  G   G H           G+ H   QA   V          +G  G     A +   
Sbjct: 2324 SSAGERHGSHHQQSADSSRHSGIGHG--QASSAVRD--------SGHRGSSGSQASDSEG 2373

Query: 193  QASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             +     Q ++ + Q+G        +T   ++G S
Sbjct: 2374 HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 32/155 (20%), Positives = 54/155 (34%), Gaps = 16/155 (10%)

Query: 77   SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLG--HGVNNAAGQAGK--EADK 132
            +H G   ++   G  H      HE   G G + + + + G  H  N++ GQA    E  +
Sbjct: 3562 NHRGSAQEQSRDGSRHPTSH--HEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR 3619

Query: 133  AVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVN 192
            +  G   G H           G+ H   QA   V          +G  G     A +   
Sbjct: 3620 SSAGERHGSHHQQSADSSRHSGIGHG--QASSAVRD--------SGHRGSSGSQASDSEG 3669

Query: 193  QASKEANQLLNGNHQSGSSSHQGGATTTPLASGAS 227
             +     Q ++ + Q+G        +T   ++G S
Sbjct: 3670 HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 3704


>gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Homo
            sapiens]
          Length = 2378

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 42/165 (25%), Positives = 65/165 (39%), Gaps = 12/165 (7%)

Query: 34   EGINRGLSNAEREVG----KALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQG 89
            E   +G++N +   G     A  G+ + +   G   E   +G++N  +  G   +  VQG
Sbjct: 942  EDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQG 1001

Query: 90   LNH--GMDKVAHE-INHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGK 146
            + H   +  +A+E   HGI       E   HG+ N     G   + A QG    V   G 
Sbjct: 1002 IAHKDAIQGIANEDAAHGIAN-----EVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 1056

Query: 147  EAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
              E   QG+ +     G   E   QG  H     G   ++A +GV
Sbjct: 1057 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1101



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 48/189 (25%), Positives = 74/189 (39%), Gaps = 13/189 (6%)

Query: 23   AASDDPIEKVIEGINR-----GLSNAEREVGKALDGINSGITHAGREVEKVFNGLSN--M 75
            AA     E V +GI       G++N +     A      GI + G   E V +G++   +
Sbjct: 2025 AAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAV 2084

Query: 76   GSHTGKELDKGV--QGLNHGMDK--VAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEAD 131
               T +E  + +  Q   HG+ K   A  + + +   G   E   HGV N     G   +
Sbjct: 2085 QGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE 2144

Query: 132  KAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
             A QG    V   G   E   QGV +  +  G   +   QG  +     G   + A +GV
Sbjct: 2145 DAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGV 2204

Query: 192  NQASKEANQ 200
              A+++A Q
Sbjct: 2205 --ANEDAAQ 2211



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 44/181 (24%), Positives = 67/181 (37%), Gaps = 12/181 (6%)

Query: 18   ALSGWAASDDPIEKVIEGINRGLSNAEREVG----KALDGINSGITHAGREVEKVFNGLS 73
            A+ G A  D       E    G++N +   G     A  GI + +   G   E    G++
Sbjct: 1007 AIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIA 1066

Query: 74   NMGSHTGKELDKGVQGLNH--GMDKVAHE-INHGIGQAGKEAEKLGHGVNNAAGQAGKEA 130
            N  +  G   +   QG+ H   +  +A+E   HG+ +     E   HGV N     G   
Sbjct: 1067 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK-----EVAAHGVANEDPVQGVAN 1121

Query: 131  DKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNG 190
            + AVQG    V   G   E   QG+ +     G   E    G  +     G   ++A  G
Sbjct: 1122 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181

Query: 191  V 191
            +
Sbjct: 1182 I 1182



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 39/153 (25%), Positives = 58/153 (37%), Gaps = 13/153 (8%)

Query: 23  AASDDPIEKVIEGINR-----GLSNAEREVGKALDGINSGITHA----GREVEKVFNGLS 73
           AA D   E   +GI++     G++N +   G A +    G+ +     G   E    G++
Sbjct: 181 AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA 240

Query: 74  NMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKA 133
           N     G   +  VQG+ +  +  AH I + +   G   E    G+ N     G   + A
Sbjct: 241 NEVEVQGVAHEDAVQGIAN--EDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298

Query: 134 VQGF--HTGVHQAGKEAEKLGQGVNHAADQAGK 164
           VQG      VH   KE    G     AA    K
Sbjct: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAK 331



 Score = 35.0 bits (79), Expect = 0.060
 Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 13/157 (8%)

Query: 38   RGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNH--GMD 95
            +G++N +     A  GI + +   G   E    G++N  +  G   +   QG+ H   + 
Sbjct: 1622 QGIANQD-----AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1676

Query: 96   KVAHE-INHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQG 154
             +A+E   HG+ +     E   HGV N     G   + AVQG    V   G   E   QG
Sbjct: 1677 GIANEDAVHGVAK-----EVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731

Query: 155  VNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
            + +     G   E    G  +     G   ++A  G+
Sbjct: 1732 IANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGI 1768



 Score = 35.0 bits (79), Expect = 0.060
 Identities = 43/177 (24%), Positives = 65/177 (36%), Gaps = 25/177 (14%)

Query: 24   ASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKEL 83
            A++D  + + E   +G++N E     A      GIT      E    G++N         
Sbjct: 2071 ATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITK-----EDAAQGVTN--------- 2116

Query: 84   DKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQ 143
            +   QG+ +  +  AH + + +   G   E    GV N     G   + AVQG    V  
Sbjct: 2117 EVAAQGVAN--EDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEV 2174

Query: 144  AG---KEA------EKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
             G   K+A      E   QGV +     G   E   QG  +     G   ++A  GV
Sbjct: 2175 QGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGV 2231



 Score = 34.7 bits (78), Expect = 0.079
 Identities = 44/182 (24%), Positives = 72/182 (39%), Gaps = 15/182 (8%)

Query: 24  ASDDPIEKVIEGIN-RGLSN--AEREVGK--ALDGINSGITHAGREVEKVFNGLSNMGSH 78
           A++D +  V + +   G++N  A   + K  A  GI + +   G   E V +G++N  + 
Sbjct: 303 ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAA 362

Query: 79  TGKELDKGVQGLNHGMDKVAHEIN----HGIGQAGKEAEKLG-----HGVNNAAGQAGKE 129
            G   +    G+ +  D V   +N    HG+      A+ +      HG+ N     G  
Sbjct: 363 HGVAKEVTAHGVANE-DAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIA 421

Query: 130 ADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHN 189
            + A QG    V   G   E   QG+ +     G   E   QG  H     G   ++A +
Sbjct: 422 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481

Query: 190 GV 191
           GV
Sbjct: 482 GV 483



 Score = 34.7 bits (78), Expect = 0.079
 Identities = 44/192 (22%), Positives = 71/192 (36%), Gaps = 22/192 (11%)

Query: 18   ALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGS 77
            AL G  A++D  + +        +  +   G A +G+ + +   G   E V +G++   +
Sbjct: 867  ALHGVVANEDAAQAI--------AKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918

Query: 78   HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
            H G   ++  Q +       AH I +     G   E   HGV N     G   + A QG 
Sbjct: 919  H-GITKEEAAQAI--AKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975

Query: 138  --HTGVHQAGKEAEKLG-------QGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAH 188
                 VH    E    G       QG+ H     G   E    G  +     G   ++A 
Sbjct: 976  ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035

Query: 189  NGVNQASKEANQ 200
             G+  A+++A Q
Sbjct: 1036 QGI--ANEDAAQ 1045



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 47/195 (24%), Positives = 70/195 (35%), Gaps = 21/195 (10%)

Query: 18  ALSGWAASDDPIEKVI----------EGINRGLSNAEREVG----KALDGINSGITHAGR 63
           AL G  A++D  + +           E    G++N +   G     A  GI + +   G 
Sbjct: 650 ALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 709

Query: 64  EVEKVFNGLSNMGSHTGKELDKGVQGLN-----HGMDK--VAHEINHGIGQAGKEAEKLG 116
             E    G++N  +  G   +  VQG+      HG+ K   AH + +     G   E + 
Sbjct: 710 SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVV 769

Query: 117 HGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHA 176
            GV N     G   + AVQG        G   E    GV +     G   E   QG  + 
Sbjct: 770 QGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANE 829

Query: 177 AGQAGKELQNAHNGV 191
               G   ++A  GV
Sbjct: 830 DAVHGVANEDAAQGV 844



 Score = 32.7 bits (73), Expect = 0.30
 Identities = 35/158 (22%), Positives = 59/158 (37%), Gaps = 6/158 (3%)

Query: 38   RGLSNAEREVGKA----LDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHG 93
            +G++N +   G A    + G+ + +   G   E    G++N  +  G   +   QG+ + 
Sbjct: 1847 QGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIAN- 1905

Query: 94   MDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQ 153
             +  A +I +     G   E    G+ N     G   + AVQG        G   E    
Sbjct: 1906 -EDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964

Query: 154  GVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
            G+ +     G   E   QG  H     G   ++A +GV
Sbjct: 1965 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 2002



 Score = 32.3 bits (72), Expect = 0.39
 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 9/148 (6%)

Query: 24   ASDDPIEKVI-EGINRGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSH 78
            A++D  + +  E   +G++N +   G A +    G+ +     G   E    G++N    
Sbjct: 1075 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1134

Query: 79   TGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF- 137
             G   +  VQG+ +  +  AH I + +   G   E    G+ N     G   + AVQG  
Sbjct: 1135 QGVAHEDAVQGIAN--EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192

Query: 138  -HTGVHQAGKEAEKLGQGVNHAADQAGK 164
                VH   KE    G     AA    K
Sbjct: 1193 NEDAVHGVAKEVAAHGVANEDAAHAIAK 1220



 Score = 32.0 bits (71), Expect = 0.51
 Identities = 42/169 (24%), Positives = 62/169 (36%), Gaps = 11/169 (6%)

Query: 34   EGINRGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSHTGKELDKGVQG 89
            E   +G++N +   G A +    GI+      G   E    G++N  +  G   +  VQG
Sbjct: 1032 EDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1091

Query: 90   LN-----HGMDK--VAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVH 142
            +      HG+ K   AH + +     G   E    GV N     G   + AVQG      
Sbjct: 1092 IANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA 1151

Query: 143  QAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
              G   E    G+ +     G   E   QG  H     G   ++A +GV
Sbjct: 1152 AHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200



 Score = 31.2 bits (69), Expect = 0.87
 Identities = 41/174 (23%), Positives = 63/174 (36%), Gaps = 7/174 (4%)

Query: 18   ALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGS 77
            A+ G A  D       E   +G++N +   G A +    G+ +     E    G++N   
Sbjct: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVAN-----EDPIQGVANEVE 1322

Query: 78   HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
              G   +  VQG+ +  +  AH I +     G   E     + N     G   + AVQG 
Sbjct: 1323 VQGVAHEDAVQGIAN--EDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380

Query: 138  HTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
                   G   E   QGV +     G   E   QG  H     G   ++A +G+
Sbjct: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 41/173 (23%), Positives = 65/173 (37%), Gaps = 7/173 (4%)

Query: 24   ASDDPIEKVIEGIN-RGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSH 78
            A++DPI+ V   +  +G+++ +   G A +    GI +     G   E     ++N  + 
Sbjct: 1309 ANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAA 1368

Query: 79   TGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFH 138
             G   +  VQG+ +  +  A  I       G   E    GV N     G   + AVQG  
Sbjct: 1369 QGISKEDAVQGIAN--EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1426

Query: 139  TGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
                  G   E    G+ +     G   E   QG  H     G   ++A +GV
Sbjct: 1427 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1479



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 50/216 (23%), Positives = 79/216 (36%), Gaps = 41/216 (18%)

Query: 24   ASDDPIEKVI-EGINRGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSH 78
            A++DP++ V  E   +G++N     G A +    GI +     G   E   +G++N  + 
Sbjct: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756

Query: 79   TGKELDKGVQGLNH--GMDKVAHEIN-HGIGQA--------------------------- 108
             G   +  VQG+ +   +  VA E+  HG+                              
Sbjct: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816

Query: 109  ----GKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGK 164
                G   E   HGV N     G   + AVQG        G   E   QGV +  +  G 
Sbjct: 1817 DVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGV 1876

Query: 165  EVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQ 200
              E   QG  +     G   ++A  G+  A+++A Q
Sbjct: 1877 AHEDAVQGIANEDAAHGIANEDAAQGI--ANEDAAQ 1910



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 9/182 (4%)

Query: 24   ASDDPIEKVI-EGINRGLSNAEREVGKALDGINSGITH--AGREVEK--VFNGLSNMGSH 78
            A++D  + +  E   +G++N +   G A +    G+ +  A   + K     G++N  + 
Sbjct: 1174 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233

Query: 79   TGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFH 138
             G   +    G+ +  +  AH + + +   G   E    G+ N     G   + AVQG  
Sbjct: 1234 QGIATEDVADGIAN--EDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIA 1291

Query: 139  TGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEA 198
                  G   E   QGV +     G   E   QG  H     G   ++A +G+  A+++A
Sbjct: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGI--ANEDA 1349

Query: 199  NQ 200
             Q
Sbjct: 1350 AQ 1351



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 50/207 (24%), Positives = 71/207 (34%), Gaps = 29/207 (14%)

Query: 18   ALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGS 77
            A+ G A  D       E    G++N +   G A +    GI H     E    G++N  +
Sbjct: 1421 AVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH-----EDAVQGIANEDA 1475

Query: 78   HTGKELDKGVQGLN-----HGMDK--VAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEA 130
              G   +    G+      H + K   A  I + +   G   E +  G+ N     G   
Sbjct: 1476 VHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVAN 1535

Query: 131  DKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQG-----------AHHAAGQ 179
            + A QG    V   G   E   QGV       G   E   QG           A+  A Q
Sbjct: 1536 EVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQ 1595

Query: 180  AGKELQNAHNGVNQ------ASKEANQ 200
            A  +   AH   N+      A+K+A Q
Sbjct: 1596 AIAKPDAAHGIANEVAAHSIANKDAAQ 1622



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 43/184 (23%), Positives = 63/184 (34%), Gaps = 30/184 (16%)

Query: 38   RGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSHTGKELDKGVQGL--- 90
            RG++N     G A + +  GI +     G   E    G++N  +  G  ++  VQG+   
Sbjct: 1504 RGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKE 1563

Query: 91   --NHGM-----------DKVAHEI--NHGIGQA--------GKEAEKLGHGVNNAAGQAG 127
               HG+           +   H +  N    QA        G   E   H + N     G
Sbjct: 1564 VTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQG 1623

Query: 128  KEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNA 187
                 A QG    V   G   E   QG+ +     G   E   QG  H     G   ++A
Sbjct: 1624 IANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1683

Query: 188  HNGV 191
             +GV
Sbjct: 1684 VHGV 1687



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 39/169 (23%), Positives = 63/169 (37%), Gaps = 7/169 (4%)

Query: 38  RGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSHTGKELDKGVQGLNHG 93
           +G++N +   G A +    GI +     G   E   +G++N     G   +  VQG+ + 
Sbjct: 716 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775

Query: 94  MDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQ 153
           ++     I H     G   E   HG+ N     G   + A QG        G   E    
Sbjct: 776 VE--VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVH 833

Query: 154 GVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLL 202
           GV +     G   E    G  +     G   + A +GV  A+++A Q +
Sbjct: 834 GVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV-VANEDAAQAI 881



 Score = 28.5 bits (62), Expect = 5.6
 Identities = 49/206 (23%), Positives = 73/206 (35%), Gaps = 36/206 (17%)

Query: 24  ASDDPIEKVIEGIN-RGLSN--AEREVGK--ALDGINSGITHAGREVEKVFNGLSNMGSH 78
           A++D +  V + +   G++N  A   + K  A  GI + +   G   E V +G++N  + 
Sbjct: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534

Query: 79  TGKELDKGVQGLNHGMDKVAHEIN-----HGIGQA-------------GKEAEKLGHGVN 120
            G   +    G+ +  +  AH I      HGI                G   E   HGV 
Sbjct: 535 HGVANEVAAHGVAN--EDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 592

Query: 121 NAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQG-------- 172
           N     G   + AVQG        G   E   QG+       G   E   QG        
Sbjct: 593 NEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALH 652

Query: 173 ---AHHAAGQAGKELQNAHNGVNQAS 195
              A+  A QA  +   AH   N+ +
Sbjct: 653 GVVANEDAAQAIAKPDAAHGIANEVA 678



 Score = 28.1 bits (61), Expect = 7.4
 Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 4/111 (3%)

Query: 92  HGM--DKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAE 149
           HG+  +     + + +   G   E   HGV N     G   + A QG    V   G   E
Sbjct: 66  HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANE 125

Query: 150 KLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQ 200
              QGV +     G   E   QG  +     G   ++A  G+  A+++A Q
Sbjct: 126 DAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGI--ANEDAAQ 174



 Score = 28.1 bits (61), Expect = 7.4
 Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 7/164 (4%)

Query: 39  GLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSHTGKELDKGVQGLNHGM 94
           G++N     G A + +  GI +     G   E   +G++N  +  G   +  + G+    
Sbjct: 337 GIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANE 396

Query: 95  DKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQG 154
           D  A  I       G   E   HG+ N     G   + A  G        G   E   QG
Sbjct: 397 D-AAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 455

Query: 155 VNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEA 198
           + H     G   E   QG  +     G   + A +GV  A+K+A
Sbjct: 456 IAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV--ANKDA 497


>gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a
           [Homo sapiens]
          Length = 730

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 9/140 (6%)

Query: 36  INRGLSNAER--EVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHG 93
           IN  LSNA +  E+     G   G +  G  +E++  G+  +G   G  +++   GL HG
Sbjct: 372 INEILSNALKRGEIIAKQGGGGGGGSVPG--IERMGPGIDRLG---GAGMERMGAGLGHG 426

Query: 94  MDKVAHEINHG--IGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKL 151
           MD+V  EI     +       E++G G+             +++     + + G   E++
Sbjct: 427 MDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERM 486

Query: 152 GQGVNHAADQAGKEVEKLGQ 171
           G G+    ++    ++++GQ
Sbjct: 487 GAGMGFGLERMAAPIDRVGQ 506



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 32/137 (23%), Positives = 53/137 (38%), Gaps = 20/137 (14%)

Query: 36  INRGLSNAE-REVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGM 94
           +N+G+        G  ++GI  GI   G        G+ NMG            G+N G 
Sbjct: 320 LNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGS--------GMNMGR 371

Query: 95  DKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEA-EKLGQ 153
                     I +    A K G  +    G  G  +   ++    G+ + G    E++G 
Sbjct: 372 ----------INEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGA 421

Query: 154 GVNHAADQAGKEVEKLG 170
           G+ H  D+ G E+E++G
Sbjct: 422 GLGHGMDRVGSEIERMG 438



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 31/139 (22%), Positives = 62/139 (44%), Gaps = 22/139 (15%)

Query: 36  INRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMD 95
           + R  S  ER     LD + S I   G+ +E++ +G+  MG+           G+  G++
Sbjct: 447 VERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGA-----------GMGFGLE 495

Query: 96  KVAHEINHGIGQAGKEAEKLGHGVNN---AAGQAGKEADKAV-QGFHTGVHQAGKEAEKL 151
           ++A  I+    + G+  E++G GV     A  + G   ++ V  G   G+ + G   +++
Sbjct: 496 RMAAPID----RVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRM 551

Query: 152 GQGVNHAADQAGKEVEKLG 170
             G+          +E++G
Sbjct: 552 ATGLER---MGANNLERMG 567



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 23/128 (17%)

Query: 28  PIEKVIEGINRGLSNAEREVGKALD------------GINSGITHAGREVEKVFNGLSNM 75
           PI++V + I R  S  ER +G A++            G+ +G+   G  ++++  GL  M
Sbjct: 500 PIDRVGQTIERMGSGVER-MGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERM 558

Query: 76  GSHTGKELDKGVQGLNH----GMDKVAHEINHGIGQAGKEAEKLGHGVNN----AAGQAG 127
           G++  + +     G N     G++++       +G A   A  LG G+        G  G
Sbjct: 559 GANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPA--LGAGIERMGLAMGGGGG 616

Query: 128 KEADKAVQ 135
              D+A++
Sbjct: 617 ASFDRAIE 624


>gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b
           [Homo sapiens]
          Length = 691

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 9/140 (6%)

Query: 36  INRGLSNAER--EVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHG 93
           IN  LSNA +  E+     G   G +  G  +E++  G+  +G   G  +++   GL HG
Sbjct: 333 INEILSNALKRGEIIAKQGGGGGGGSVPG--IERMGPGIDRLG---GAGMERMGAGLGHG 387

Query: 94  MDKVAHEINHG--IGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKL 151
           MD+V  EI     +       E++G G+             +++     + + G   E++
Sbjct: 388 MDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERM 447

Query: 152 GQGVNHAADQAGKEVEKLGQ 171
           G G+    ++    ++++GQ
Sbjct: 448 GAGMGFGLERMAAPIDRVGQ 467



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 32/137 (23%), Positives = 53/137 (38%), Gaps = 20/137 (14%)

Query: 36  INRGLSNAE-REVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGM 94
           +N+G+        G  ++GI  GI   G        G+ NMG            G+N G 
Sbjct: 281 LNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGS--------GMNMGR 332

Query: 95  DKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEA-EKLGQ 153
                     I +    A K G  +    G  G  +   ++    G+ + G    E++G 
Sbjct: 333 ----------INEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGA 382

Query: 154 GVNHAADQAGKEVEKLG 170
           G+ H  D+ G E+E++G
Sbjct: 383 GLGHGMDRVGSEIERMG 399



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 31/139 (22%), Positives = 62/139 (44%), Gaps = 22/139 (15%)

Query: 36  INRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMD 95
           + R  S  ER     LD + S I   G+ +E++ +G+  MG+           G+  G++
Sbjct: 408 VERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGA-----------GMGFGLE 456

Query: 96  KVAHEINHGIGQAGKEAEKLGHGVNN---AAGQAGKEADKAV-QGFHTGVHQAGKEAEKL 151
           ++A  I+    + G+  E++G GV     A  + G   ++ V  G   G+ + G   +++
Sbjct: 457 RMAAPID----RVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRM 512

Query: 152 GQGVNHAADQAGKEVEKLG 170
             G+          +E++G
Sbjct: 513 ATGLER---MGANNLERMG 528



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 23/128 (17%)

Query: 28  PIEKVIEGINRGLSNAEREVGKALD------------GINSGITHAGREVEKVFNGLSNM 75
           PI++V + I R  S  ER +G A++            G+ +G+   G  ++++  GL  M
Sbjct: 461 PIDRVGQTIERMGSGVER-MGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERM 519

Query: 76  GSHTGKELDKGVQGLNH----GMDKVAHEINHGIGQAGKEAEKLGHGVNN----AAGQAG 127
           G++  + +     G N     G++++       +G A   A  LG G+        G  G
Sbjct: 520 GANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPA--LGAGIERMGLAMGGGGG 577

Query: 128 KEADKAVQ 135
              D+A++
Sbjct: 578 ASFDRAIE 585


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/155 (23%), Positives = 62/155 (40%), Gaps = 10/155 (6%)

Query: 62   GREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKE-AEKLGHGVN 120
            G E E  + G    G   G+E  +G      G  +       G  + G+E  E+ G G  
Sbjct: 948  GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007

Query: 121  NAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQA 180
               G+  +E +  V+G        G+E E  G+G     ++ G+E EK G+G  +   + 
Sbjct: 1008 EGEGEGEEEEEGEVEG-----EVEGEEGE--GEGEEEEGEEEGEEREKEGEGEENRRNR- 1059

Query: 181  GKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
             +E +       +  +E N+  +G      S  +G
Sbjct: 1060 -EEEEEEEGKYQETGEEENERQDGEEYKKVSKIKG 1093



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 40/179 (22%), Positives = 63/179 (35%), Gaps = 8/179 (4%)

Query: 39  GLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVA 98
           G    E   GK   G   G    G E E    G        G E++ G      G  +  
Sbjct: 773 GERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK---EEGGEVEGGEVEEGKGEREEE 829

Query: 99  HEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHA 158
            E   G  + G+  E+ G G        G+E  +  +G   G    G+  E+ G+G    
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889

Query: 159 ADQA-GKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGG 216
             +  G+E E  G+G     G+ G+E +    G  +  +   +   G  + G    + G
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGE-GEEEEGEGKGEEEGEEGEGE---GEEEEGEGEGEDG 944



 Score = 35.0 bits (79), Expect = 0.060
 Identities = 38/178 (21%), Positives = 66/178 (37%), Gaps = 15/178 (8%)

Query: 38   RGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKV 97
            +G    E E G+  +    G    G   E+   G        G+  ++G +G   G ++ 
Sbjct: 823  KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 98   AHEINHGIGQA-GKEAEKLGHGVNNAAGQA------GKEADKAVQGFHTGVHQAGK-EAE 149
                    G+  G+E E  G G     G+       GK  ++  +G   G  + G+ E E
Sbjct: 883  GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942

Query: 150  K-LGQGVNHAADQAGKEVEKLGQGAHHAAGQA------GKELQNAHNGVNQASKEANQ 200
               G+G     +  G+E E  G+G     G+       G+E +    G  +  +E  +
Sbjct: 943  DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000



 Score = 28.1 bits (61), Expect = 7.4
 Identities = 31/129 (24%), Positives = 50/129 (38%), Gaps = 12/129 (9%)

Query: 43  AEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEIN 102
           AE+E  K  DG         +E E+      N     G E + G +G     D+   E  
Sbjct: 697 AEKEEWKKRDGEEQ----EQKEREQGHQKERNQEMEEGGEEEHG-EGEEEEGDREEEEEK 751

Query: 103 HGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQA 162
            G G+   E E++        G+  KE  +  +    G  + G+E    G+G     +  
Sbjct: 752 EGEGKEEGEGEEV-------EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGR 804

Query: 163 GKEVEKLGQ 171
           G+E E+ G+
Sbjct: 805 GEEKEEGGE 813


>gi|171916097 repetin [Homo sapiens]
          Length = 784

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 2/134 (1%)

Query: 82  ELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGV 141
           ++D+  QG ++G      + +H  GQ  ++ +   +G  +  GQ+        QG  +  
Sbjct: 417 QMDRQGQGSHYGQTDRQGQSSH-YGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHY 475

Query: 142 HQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQL 201
            Q  K+ +    G     DQ+    +  GQG     GQ  ++ Q+ H G      +++  
Sbjct: 476 SQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHY 535

Query: 202 LNGNHQSGSSSHQG 215
              + Q G SSH G
Sbjct: 536 SQMDRQ-GQSSHYG 548



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 33/142 (23%), Positives = 64/142 (45%), Gaps = 19/142 (13%)

Query: 76  GSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAG--KEADKA 133
           GSH  +   +G Q  ++G      + +H  GQ  ++ +   +G     GQ+    + D+ 
Sbjct: 364 GSHYSQPNRQG-QSSHYGQPDTQDQSSH-YGQTDRQDQSSHYGQTERQGQSSHYSQMDRQ 421

Query: 134 VQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQ 193
            QG H G      + ++ GQ  ++       + ++ GQ +H+  GQ  ++ Q++H G   
Sbjct: 422 GQGSHYG------QTDRQGQSSHYG------QPDRQGQNSHY--GQTDRQGQSSHYGQTD 467

Query: 194 ASKEANQLLNGNHQSGSSSHQG 215
              +++     + Q G SSH G
Sbjct: 468 RQGQSSHYSQPDKQ-GQSSHYG 488



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 9/143 (6%)

Query: 76  GSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAG--KEADKA 133
           GSH G + D+  Q  ++G      + +H  GQ  ++ +   +G  +  GQ+    + DK 
Sbjct: 424 GSHYG-QTDRQGQSSHYGQPDRQGQNSH-YGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQ 481

Query: 134 VQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQ 193
            Q  H G      ++   GQ           + ++ GQ  H+  GQ  ++ Q++H   +Q
Sbjct: 482 GQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHY--GQPDRQGQSSH--YSQ 537

Query: 194 ASKEANQLLNG-NHQSGSSSHQG 215
             ++      G   + G SSH G
Sbjct: 538 MDRQGQSSHYGQTDRQGQSSHYG 560



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 31/138 (22%), Positives = 61/138 (44%), Gaps = 9/138 (6%)

Query: 77  SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAG--KEADKAV 134
           SH GK +D+  Q  ++G      + +H  GQ  ++ +   +G  +  GQ+    + D+  
Sbjct: 485 SHYGK-IDRQDQSYHYGQPDGQGQSSH-YGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQG 542

Query: 135 QGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGK-ELQNAHNGVNQ 193
           Q  H G      ++   GQ           + ++ GQ +H+   Q G+ + QN +    +
Sbjct: 543 QSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTE 602

Query: 194 ASKEANQLLNGNHQSGSS 211
            +++A+ +     QSG S
Sbjct: 603 GTRKASYV----EQSGRS 616



 Score = 32.0 bits (71), Expect = 0.51
 Identities = 31/140 (22%), Positives = 65/140 (46%), Gaps = 21/140 (15%)

Query: 77  SHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGK--EADKAV 134
           SH G + D+  Q  ++       + +H  G+  ++ +   +G  +  GQ+    + D+  
Sbjct: 461 SHYG-QTDRQGQSSHYSQPDKQGQSSH-YGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQG 518

Query: 135 QGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQA 194
           Q FH G      + ++ GQ  +++      ++++ GQ +H+  GQ  ++ Q++H G  Q 
Sbjct: 519 QSFHYG------QPDRQGQSSHYS------QMDRQGQSSHY--GQTDRQGQSSHYG--QT 562

Query: 195 SKEANQLLNG-NHQSGSSSH 213
            ++      G   + G SSH
Sbjct: 563 DRQGQSYHYGQTDRQGQSSH 582



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 24/112 (21%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 106 GQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGK- 164
           GQ  ++ +   +   N  GQ    +    QG  +   Q   + +    G     DQ+   
Sbjct: 344 GQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHY 403

Query: 165 -EVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
            + E+ GQ +H++  Q  ++ Q +H G      +++     + Q G +SH G
Sbjct: 404 GQTERQGQSSHYS--QMDRQGQGSHYGQTDRQGQSSHYGQPDRQ-GQNSHYG 452


>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
          Length = 416

 Score = 37.7 bits (86), Expect = 0.009
 Identities = 31/137 (22%), Positives = 48/137 (35%), Gaps = 7/137 (5%)

Query: 71  GLSNMGSHTGKELDKGVQGLNHGMDKVAHE--INHGIGQAGKEAEKLGHGVNNAAGQAGK 128
           G SN G  +G +      G N   +  +     + G    G      G    N+ G  G 
Sbjct: 240 GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGD 299

Query: 129 EADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAH 188
              ++  G  TG           G G     ++ G E    G+     +G  G   Q   
Sbjct: 300 SGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE-----SGIQGFRGQGVS 354

Query: 189 NGVNQASKEANQLLNGN 205
           + + + SKE N+LL G+
Sbjct: 355 SNMREISKEGNRLLGGS 371



 Score = 31.2 bits (69), Expect = 0.87
 Identities = 54/252 (21%), Positives = 83/252 (32%), Gaps = 50/252 (19%)

Query: 16  LGALSGWAASDDPIEKVIEGINRGLSNAEREVGK--ALDGINSGITHAGREVEKVFNGLS 73
           +G  +G AA     E + +G    +    R+V    A D +       G  V +  + L 
Sbjct: 55  IGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADAL-------GNRVGEAAHALG 107

Query: 74  NMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKA 133
           N G   G++ +  ++   HG D V        G  G      GHG+  + G  G +    
Sbjct: 108 NTGHEIGRQAEDVIR---HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGN 164

Query: 134 VQGFHT-----------GVHQAGKEAEKLGQGVNHAADQAGKE----VEKLGQGAHHAAG 178
             G  T           G      +    GQG N      G      V + G G+  A+ 
Sbjct: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224

Query: 179 Q--------------------AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGAT 218
           Q                     G   Q+  +G        N   +G   SGSSS   G +
Sbjct: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS---GGS 281

Query: 219 TTPLASGASVNT 230
           +   + G+S N+
Sbjct: 282 SGGSSGGSSGNS 293


>gi|239746652 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1513

 Score = 36.6 bits (83), Expect = 0.021
 Identities = 39/168 (23%), Positives = 64/168 (38%), Gaps = 7/168 (4%)

Query: 24   ASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKEL 83
            A++D  + + E   +G++N E     A      GIT+     E    G++N  +  G   
Sbjct: 1179 ATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITN-----EDAAQGVTNEVAAQGVAN 1233

Query: 84   DKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQ 143
            +    G+ +  +  AH + +     G   E    GV N     G   + AVQG    V  
Sbjct: 1234 EDAAHGVAN--EVAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 1291

Query: 144  AGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
             G   +   QG+ +     G   E   QG  +     G   ++A +GV
Sbjct: 1292 QGIAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHGVANEDAAHGV 1339



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 41/174 (23%), Positives = 65/174 (37%), Gaps = 20/174 (11%)

Query: 18  ALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGS 77
           AL G  A++D  + +        +  +   G A +G+ + +   G   E V +G++   +
Sbjct: 290 ALHGVVANEDAAQAI--------AKPDSAHGIANEGVANEVAAQGIATEDVADGIAEDAA 341

Query: 78  HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
           H G   ++  Q +       AH I +     G   E   HGV N         + A QG 
Sbjct: 342 H-GITNEEAAQAI--AKQDAAHSITNEDAVQGVANEDAAHGVAN---------EDAAQGI 389

Query: 138 HTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
              V   G   E   QG+ +     G   E   QG  H     G   ++A +GV
Sbjct: 390 ANEVATHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 443



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 14/171 (8%)

Query: 25  SDDPIEKVI-EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKEL 83
           ++D ++ V  E    G++N +     A  GI + +   G   E    G++N  +  G   
Sbjct: 364 NEDAVQGVANEDAAHGVANED-----AAQGIANEVATHGISKEDAVQGIANEDAAQGIAN 418

Query: 84  DKGVQGLNH--GMDKVAHE-INHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTG 140
           +   QG+ H   +  +A+E   HG+ +     E   HGV N     G   + AVQG    
Sbjct: 419 EDAAQGIAHEDAVQGIANEDAVHGVAK-----EVAAHGVANEDPVQGVANEDAVQGVANE 473

Query: 141 VHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
           V   G   E   QG+ +     G   E    G  +     G   ++A  G+
Sbjct: 474 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 524



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 39/161 (24%), Positives = 62/161 (38%), Gaps = 13/161 (8%)

Query: 34  EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNH- 92
           E   +G++N +     A  GI + +   G   E    G++N  +  G   +   QG+ H 
Sbjct: 681 EDAAQGIANED-----AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 735

Query: 93  -GMDKVAHE-INHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEK 150
             +  +A+E   HG+ +     E   HGV N     G   + AVQG    V   G   E 
Sbjct: 736 DAVQGIANEDAVHGVAK-----EVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHED 790

Query: 151 LGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
             QG+ +     G   E    G  +     G   ++A  G+
Sbjct: 791 AVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGI 831



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 41/173 (23%), Positives = 68/173 (39%), Gaps = 8/173 (4%)

Query: 34   EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSN--MGSHTGKELDKGV--QG 89
            E   + ++  +   G A +G+ + +   G   E V +G++   +   T +E  + +  Q 
Sbjct: 1149 EDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 1208

Query: 90   LNHGM--DKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKE 147
              HG+  +  A  + + +   G   E   HGV N     G   + A QG    V   G  
Sbjct: 1209 AAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 1268

Query: 148  AEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQ 200
             E    GV +     G   E   QG  H     G   ++A  GV  A+++A Q
Sbjct: 1269 NEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGV--ANEDAAQ 1319



 Score = 31.6 bits (70), Expect = 0.67
 Identities = 36/149 (24%), Positives = 54/149 (36%), Gaps = 9/149 (6%)

Query: 18   ALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGS 77
            A  G A  D   +   E   +G++  +   G A +    G+ +     E    G++N   
Sbjct: 971  AAQGIANEDAAQDIANEDAAQGIAKEDPVQGVANEDPVQGVAN-----EDAVQGVANEVE 1025

Query: 78   HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
              G   +  VQG+ +  +  AH I + +   G   E    G+ N     G   + AVQG 
Sbjct: 1026 VQGVAHEDAVQGIAN--EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1083

Query: 138  --HTGVHQAGKEAEKLGQGVNHAADQAGK 164
                 VH   KE    G     AA    K
Sbjct: 1084 ANEDAVHGVAKEVAAHGVANEDAAHAIAK 1112



 Score = 31.2 bits (69), Expect = 0.87
 Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 4/131 (3%)

Query: 70  NGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKE 129
           +G++N  +  G   +   QG+ +  +  AH + + +   G   E    GV N     G  
Sbjct: 139 HGITNEDAVQGVANEVAAQGVAN--EDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 196

Query: 130 ADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHN 189
            + A QG        G   E    G+ +     G   E   QG  +     G   ++A +
Sbjct: 197 NEDAAQGVANEDAVQGVANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVH 256

Query: 190 GVNQASKEANQ 200
           GV  A+++A Q
Sbjct: 257 GV--ANEDAAQ 265



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 55/247 (22%), Positives = 91/247 (36%), Gaps = 45/247 (18%)

Query: 24   ASDDPIEKVIEGIN-RGLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSH 78
            A++D ++ V   +  +G+++ +   G A +    GIT+     G   E    G++N  + 
Sbjct: 769  ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAA 828

Query: 79   TGKELDKGVQGLNH--GMDKVAHEIN-HGIGQA--------------------------- 108
             G   +  VQG+ +   +  VA E+  HG+                              
Sbjct: 829  QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 888

Query: 109  ----GKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGK 164
                G   E   HGV N     G   + AVQG        G   E   QGV +  +  G 
Sbjct: 889  DVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGV 948

Query: 165  EVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQ-LLNGNHQSGSSSH---QGGATTT 220
              E   QG  +     G   ++A  G+  A+++A Q + N +   G +     QG A   
Sbjct: 949  AHEDAVQGIANEDAAHGIANEDAAQGI--ANEDAAQDIANEDAAQGIAKEDPVQGVANED 1006

Query: 221  PLASGAS 227
            P+   A+
Sbjct: 1007 PVQGVAN 1013



 Score = 28.1 bits (61), Expect = 7.4
 Identities = 39/183 (21%), Positives = 68/183 (37%), Gaps = 7/183 (3%)

Query: 39  GLSNAEREVGKALDGINSGITHA----GREVEKVFNGLSNMGSHTGKELDKGVQGLNHGM 94
           G++N +   G A +    G+ +     G   E   +G++N  +  G   +   QG+ +  
Sbjct: 140 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN-- 197

Query: 95  DKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQG 154
           +  A  + +     G   E   HG+ N     G   + A QG        G   E    G
Sbjct: 198 EDAAQGVANEDAVQGVANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHG 257

Query: 155 VNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQ 214
           V +     G   E    G  +     G   Q A +GV  A+++A Q +     +   +++
Sbjct: 258 VANEDAAQGVAKEVTAHGVTNEDAVQGVVNQEALHGV-VANEDAAQAIAKPDSAHGIANE 316

Query: 215 GGA 217
           G A
Sbjct: 317 GVA 319



 Score = 27.7 bits (60), Expect = 9.6
 Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 8/169 (4%)

Query: 24   ASDDPIEKVIEGIN-RGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKE 82
            A +DPI+ V   +  +G+++ +   G A +    GI +     E    G++N  +     
Sbjct: 931  AKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN-----EDAAQGIANEDAAQDIA 985

Query: 83   LDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVH 142
             +   QG+    D V    N    Q G   E    GV N     G   + AVQG      
Sbjct: 986  NEDAAQGIAKE-DPVQGVANEDPVQ-GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA 1043

Query: 143  QAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGV 191
              G   E    G+ +     G   E   QG  H     G   ++A +GV
Sbjct: 1044 AHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1092


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 35.8 bits (81), Expect = 0.035
 Identities = 49/204 (24%), Positives = 77/204 (37%), Gaps = 38/204 (18%)

Query: 48   GKALDGINSGITHAGREVEKVFNGLSNMGS-HTGKELDKGVQGLNHGMDKVAHEINHGIG 106
            G+  D    G    G+ ++         GS H+     +G  G++H      H   H  G
Sbjct: 1924 GQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSH-----THS-GHTHG 1977

Query: 107  QAGKEAEKLGHGVNNAAGQA-GKEADKAVQGFHTGVHQAGKEAEKLG------------- 152
            QAG    + G  V+   G   G+ AD    G H+G  Q+ +   +               
Sbjct: 1978 QAGSHYPESGSSVHERHGTTHGQTADTTRHG-HSGHGQSTQRGSRTTGRRASGHSEYSDS 2036

Query: 153  ---QGVNH-----AADQAGKEVEKLGQGAHH----AAGQAGKELQNAHNGVNQA----SK 196
                GV+H     A  QAG +  + G   H       GQ G   ++AH+G  Q+    S+
Sbjct: 2037 EGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSR 2096

Query: 197  EANQLLNGNHQSGSSSHQGGATTT 220
             A +  +G+ +S  S    G + T
Sbjct: 2097 TAGRRGSGHSESSDSEVHSGVSHT 2120



 Score = 34.7 bits (78), Expect = 0.079
 Identities = 41/180 (22%), Positives = 66/180 (36%), Gaps = 33/180 (18%)

Query: 42   NAEREVGKALDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGM--DKVAH 99
            +++ EV       +SG TH+        +G S    H       G QG  HG   D   H
Sbjct: 2183 SSDSEVHSEASPTHSGHTHSQAGSR---HGQSGSSGH-------GRQGTTHGQTGDTTRH 2232

Query: 100  EINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAA 159
              ++G GQ+ +   +            G+      +   + VH  G           H  
Sbjct: 2233 A-HYGYGQSTQRGSRT----------TGRRGSGHSESSDSEVHSWGSHTHS-----GHIQ 2276

Query: 160  DQAGKEVEKLGQGAHHAA----GQAGKELQNAHNGVNQASKEANQLLNGNH-QSGSSSHQ 214
             QAG +  + G   H       GQ G   ++ H+G  Q+++  ++    +H QS SS  Q
Sbjct: 2277 GQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQ 2336



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 35/157 (22%), Positives = 53/157 (33%), Gaps = 9/157 (5%)

Query: 62  GREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQA---GKEAEKLGHG 118
           G+   +  +G    GS + +    G  G   G      +   G GQ+   G+   + GH 
Sbjct: 632 GQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHS 691

Query: 119 VNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAG 178
                G    ++    Q   +    +G    +L  G + +  Q G      G G     G
Sbjct: 692 SYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGS-----GSGQSSGFG 746

Query: 179 QAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
           Q G       +G  Q    + Q   G H SGSS   G
Sbjct: 747 QHGSG-SGQSSGFGQHESRSGQSSYGQHSSGSSQSSG 782



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 42/182 (23%), Positives = 65/182 (35%), Gaps = 27/182 (14%)

Query: 41   SNAEREVGKALDGINSGITHA---GREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKV 97
            S + +  G    G +SG T      R     ++G    GS +G+    G  G   G    
Sbjct: 850  SGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYS- 908

Query: 98   AHEINHGIGQAGKEAEKLGHGVNNAAGQA----GKEADKAVQGFHTGVHQAGKEAEKLGQ 153
                  G GQ    + +  +G + +        G+    + Q F  G H++G      GQ
Sbjct: 909  ------GFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGS-----GQ 957

Query: 154  GVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSH 213
                    +G   +  G G H +   +GK      +G  Q    ++Q   G H SGSS  
Sbjct: 958  SSGFGQHGSGSG-QSSGFGQHESG--SGKS-----SGFGQHESRSSQSNYGQHGSGSSQS 1009

Query: 214  QG 215
             G
Sbjct: 1010 SG 1011



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 34/157 (21%), Positives = 57/157 (36%), Gaps = 9/157 (5%)

Query: 62  GREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNN 121
           G+   +  +G    GS + +    G  G   G      +   G GQ+    +       +
Sbjct: 784 GQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQS 843

Query: 122 AAGQAGKEADKAVQGFHTGVHQAGKEAEK---LGQGVNHAADQAGKEVEKLGQGAHHAAG 178
           + GQ G  + ++     +G  Q G  + +    GQ  + +   +G      G G     G
Sbjct: 844 SYGQHGSGSSQS-----SGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFG 898

Query: 179 QAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
           Q G      ++G  Q    ++Q   G H SGSS   G
Sbjct: 899 QHGTG-SGQYSGFGQHESRSHQSSYGQHGSGSSQSSG 934



 Score = 31.6 bits (70), Expect = 0.67
 Identities = 40/168 (23%), Positives = 59/168 (35%), Gaps = 25/168 (14%)

Query: 71  GLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQA---GKEAEKLG-------HG-V 119
           G    GS +GK    G  G   G      +   G GQ+   G+     G       HG V
Sbjct: 465 GYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSV 524

Query: 120 NNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQ 179
           +  +   G+   ++ Q  + G H +G  ++  G G   + + +G     LG G     GQ
Sbjct: 525 SGQSSGFGQHESRSRQSSY-GQHGSGS-SQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQ 582

Query: 180 AGKELQNAH------------NGVNQASKEANQLLNGNHQSGSSSHQG 215
            G     +             +G  Q    + Q   G H SGSS   G
Sbjct: 583 YGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSG 630



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 33/159 (20%), Positives = 53/159 (33%), Gaps = 16/159 (10%)

Query: 70   NGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQA-GKEAEKLGHGVNNAAGQAGK 128
            +G    GS +G+    G      G      +   G GQ+ G    + G G ++  GQ   
Sbjct: 933  SGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHES 992

Query: 129  EADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAH 188
             + ++  G H        ++   GQ  + +    G    +   G +   GQ G     + 
Sbjct: 993  RSSQSNYGQHGS---GSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSS 1049

Query: 189  ------------NGVNQASKEANQLLNGNHQSGSSSHQG 215
                        +G  Q    + Q   G H SGSS   G
Sbjct: 1050 GFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSG 1088



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 30/135 (22%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 88   QGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKE 147
            QG  HG         HG    G+  +    G   +  Q    +D      H+GV      
Sbjct: 1311 QGTTHGQR--GDTTRHGHSGHGQSTQT---GSRTSGRQRFSHSDATDSEVHSGVSHRPHS 1365

Query: 148  AEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEANQLL----N 203
             E   Q  + A  Q G+    + +      GQ G+   + H+G  Q+++  ++      +
Sbjct: 1366 QE---QTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGS 1422

Query: 204  GNHQSGSSS-HQGGA 217
            G+ +S  S  H GG+
Sbjct: 1423 GHSESSDSEVHSGGS 1437



 Score = 28.5 bits (62), Expect = 5.6
 Identities = 29/137 (21%), Positives = 53/137 (38%), Gaps = 8/137 (5%)

Query: 99   HEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEK-LGQGVNH 157
            H   H  GQAG + E+    V+   G    +        H+G  Q+ +   +  G+  + 
Sbjct: 1593 HSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSS 1652

Query: 158  AADQAGKEVEKLGQGAH--HAAGQAGKELQNAHNGVNQA-----SKEANQLLNGNHQSGS 210
             ++ +  EV       H  H  GQAG +   + + V +       +  +   + ++  G 
Sbjct: 1653 HSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGL 1712

Query: 211  SSHQGGATTTPLASGAS 227
            ++  G  TT    SG S
Sbjct: 1713 TTQTGSRTTGRRGSGHS 1729


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 47/181 (25%), Positives = 63/181 (34%), Gaps = 37/181 (20%)

Query: 37   NRGLSNAEREVGK-ALDGIN-----SGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGL 90
            NRGL+  E EVG+  +DG+N     +G+   GR+ EK   G        G   D+G +GL
Sbjct: 1450 NRGLNGQEGEVGENGIDGLNGEQGDNGLP--GRKGEKGDEGSQGSPGKRGTPGDRGAKGL 1507

Query: 91   --NHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF--HTGVH---- 142
              + G   V   I    G  G+   +   G     G  G     A  G   HTG      
Sbjct: 1508 RGDPGAPGVDSSIEGPTGLKGERGRQGRRGWPGPPGTPGSRRKTAAHGRRGHTGPQGTAG 1567

Query: 143  ---------------------QAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAG 181
                                 +AG + EK G G        G   E   QG   + G  G
Sbjct: 1568 IPGPDGLEGSLGLKGPQGPRGEAGVKGEKGGVGSKGPQGPPGPGGEAGNQGRLGSQGNKG 1627

Query: 182  K 182
            +
Sbjct: 1628 E 1628


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 33.1 bits (74), Expect = 0.23
 Identities = 22/64 (34%), Positives = 29/64 (45%)

Query: 118 GVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAA 177
           G   AAG+ GK  ++ V G    V  AGK+ E   QG    A  AG+  E+   G+    
Sbjct: 584 GPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643

Query: 178 GQAG 181
           G  G
Sbjct: 644 GLPG 647



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 3/77 (3%)

Query: 106 GQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKE 165
           G AG++      G   A GQAG       +G      + GK  E+   G   A   AGK+
Sbjct: 557 GPAGQDGRPGPPGPPGARGQAGVMGFPGPKG---AAGEPGKAGERGVPGPPGAVGPAGKD 613

Query: 166 VEKLGQGAHHAAGQAGK 182
            E   QG    AG AG+
Sbjct: 614 GEAGAQGPPGPAGPAGE 630


>gi|18702331 OTU domain containing 7A [Homo sapiens]
          Length = 926

 Score = 33.1 bits (74), Expect = 0.23
 Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 5/101 (4%)

Query: 120 NNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQ 179
           N+  G+ GK+ +K  Q       +A   A KLG        +  K +  LG   H   G+
Sbjct: 486 NSNNGKNGKDKEKEKQRKEKDKTRADSVANKLGSFSKTLGIKLKKNMGGLGGLVHGKMGR 545

Query: 180 AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGATTT 220
           A     N+ NG N  S E  +      + GS    G + +T
Sbjct: 546 A-----NSANGKNGDSAERGKEKKAKSRKGSKEESGASAST 581


>gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [Homo
           sapiens]
          Length = 340

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 87  VQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGK 146
           V  L   +D    +I    G AG+E E    G   AAG  G E     +G      + G 
Sbjct: 91  VISLPQALDAEFQDIPSEAGAAGEEEEAGDGGAAGAAGAIG-ETGAVGKGEAEATGEGGS 149

Query: 147 EAEKLGQGVNHAADQ--AGKEVEKLGQGAHHAAGQAGK 182
            +E  G G   A D+    +E  +  +GA    G AG+
Sbjct: 150 ASEAEGAGEGGAGDELRVAEEARESDEGAAGDTGPAGE 187


>gi|169216749 PREDICTED: similar to Putative paraneoplastic
           antigen-like protein 6B-like protein [Homo sapiens]
          Length = 340

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 87  VQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGK 146
           V  L   +D    +I    G AG+E E    G   AAG  G E     +G      + G 
Sbjct: 91  VISLPQALDAEFQDIPSEAGAAGEEEEAGDGGAAGAAGAIG-ETGAVGKGEAEATGEGGS 149

Query: 147 EAEKLGQGVNHAADQ--AGKEVEKLGQGAHHAAGQAGK 182
            +E  G G   A D+    +E  +  +GA    G AG+
Sbjct: 150 ASEAEGAGEGGAGDELRVAEEARESDEGAAGDTGPAGE 187


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 24/88 (27%), Positives = 34/88 (38%)

Query: 109  GKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEK 168
            G E E    G  +A G  G EAD A  G  T      +E+   G+G + AAD        
Sbjct: 1982 GDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGEGNHRAADSQNSGEGN 2041

Query: 169  LGQGAHHAAGQAGKELQNAHNGVNQASK 196
             G      + +  +E Q +     QA +
Sbjct: 2042 TGAAESSFSQEVSREQQPSSASERQAPR 2069


>gi|19923838 solute carrier family 13 (sodium/sulfate symporters),
           member 1 [Homo sapiens]
          Length = 595

 Score = 31.6 bits (70), Expect = 0.67
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 8/104 (7%)

Query: 19  LSGWAASDDPIEKVI---EGINRGLSNAEREVGKALDGINSGITHAGREVEKVFNGLSNM 75
           LS W ++      V+   E + + + NAE EV        +G T+ G E+++  NG    
Sbjct: 134 LSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHE-- 191

Query: 76  GSHTGKELDKGVQGLNHGMDKVAH--EINHGIGQAGKEAEKLGH 117
             +  KE  K V G N+   K++   E+    G   K   K GH
Sbjct: 192 -INERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGH 234


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 31.6 bits (70), Expect = 0.67
 Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 18/126 (14%)

Query: 78  HTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGF 137
           +  +E +  +      ++    E   G+ + G+E + L    N A  + GK+ +      
Sbjct: 782 NASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTL----NRALEEEGKQRE------ 831

Query: 138 HTGVHQAGK-EAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQN----AHNGVN 192
              V + GK E E+  + ++   D+  KE+EK+G+ +  A  Q   +L++    A   V 
Sbjct: 832 ---VLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVA 888

Query: 193 QASKEA 198
            A ++A
Sbjct: 889 DAQRQA 894


>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
          Length = 386

 Score = 31.2 bits (69), Expect = 0.87
 Identities = 54/252 (21%), Positives = 83/252 (32%), Gaps = 50/252 (19%)

Query: 16  LGALSGWAASDDPIEKVIEGINRGLSNAEREVGK--ALDGINSGITHAGREVEKVFNGLS 73
           +G  +G AA     E + +G    +    R+V    A D +       G  V +  + L 
Sbjct: 55  IGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADAL-------GNRVGEAAHALG 107

Query: 74  NMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKA 133
           N G   G++ +  ++   HG D V        G  G      GHG+  + G  G +    
Sbjct: 108 NTGHEIGRQAEDVIR---HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGN 164

Query: 134 VQGFHT-----------GVHQAGKEAEKLGQGVNHAADQAGKE----VEKLGQGAHHAAG 178
             G  T           G      +    GQG N      G      V + G G+  A+ 
Sbjct: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224

Query: 179 Q--------------------AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGAT 218
           Q                     G   Q+  +G        N   +G   SGSSS   G +
Sbjct: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS---GGS 281

Query: 219 TTPLASGASVNT 230
           +   + G+S N+
Sbjct: 282 SGGSSGGSSGNS 293


>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
          Length = 398

 Score = 31.2 bits (69), Expect = 0.87
 Identities = 54/252 (21%), Positives = 83/252 (32%), Gaps = 50/252 (19%)

Query: 16  LGALSGWAASDDPIEKVIEGINRGLSNAEREVGK--ALDGINSGITHAGREVEKVFNGLS 73
           +G  +G AA     E + +G    +    R+V    A D +       G  V +  + L 
Sbjct: 55  IGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADAL-------GNRVGEAAHALG 107

Query: 74  NMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKA 133
           N G   G++ +  ++   HG D V        G  G      GHG+  + G  G +    
Sbjct: 108 NTGHEIGRQAEDVIR---HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGN 164

Query: 134 VQGFHT-----------GVHQAGKEAEKLGQGVNHAADQAGKE----VEKLGQGAHHAAG 178
             G  T           G      +    GQG N      G      V + G G+  A+ 
Sbjct: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224

Query: 179 Q--------------------AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGAT 218
           Q                     G   Q+  +G        N   +G   SGSSS   G +
Sbjct: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS---GGS 281

Query: 219 TTPLASGASVNT 230
           +   + G+S N+
Sbjct: 282 SGGSSGGSSGNS 293


>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
          Length = 476

 Score = 31.2 bits (69), Expect = 0.87
 Identities = 54/252 (21%), Positives = 83/252 (32%), Gaps = 50/252 (19%)

Query: 16  LGALSGWAASDDPIEKVIEGINRGLSNAEREVGK--ALDGINSGITHAGREVEKVFNGLS 73
           +G  +G AA     E + +G    +    R+V    A D +       G  V +  + L 
Sbjct: 55  IGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADAL-------GNRVGEAAHALG 107

Query: 74  NMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKA 133
           N G   G++ +  ++   HG D V        G  G      GHG+  + G  G +    
Sbjct: 108 NTGHEIGRQAEDVIR---HGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGN 164

Query: 134 VQGFHT-----------GVHQAGKEAEKLGQGVNHAADQAGKE----VEKLGQGAHHAAG 178
             G  T           G      +    GQG N      G      V + G G+  A+ 
Sbjct: 165 PGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASN 224

Query: 179 Q--------------------AGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQGGAT 218
           Q                     G   Q+  +G        N   +G   SGSSS   G +
Sbjct: 225 QNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS---GGS 281

Query: 219 TTPLASGASVNT 230
           +   + G+S N+
Sbjct: 282 SGGSSGGSSGNS 293


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 31.2 bits (69), Expect = 0.87
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 18/94 (19%)

Query: 146  KEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKELQNAHNGVNQASKEA------- 198
            K+AE+  +      DQA +EV +L Q      G   +       G ++ SK+A       
Sbjct: 2333 KQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPG 2392

Query: 199  ---NQLLNG--------NHQSGSSSHQGGATTTP 221
               ++ L G        NH    S+HQ  +TTTP
Sbjct: 2393 TRVSERLRGARAETQGANHTPVISAHQTRSTTTP 2426


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 11/102 (10%)

Query: 80  GKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHT 139
           GK+   GV GL+    +         G+ G   EK  +G+    G+AG + +K  +G   
Sbjct: 304 GKDGQNGVPGLDGQKGEA--------GRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAG 355

Query: 140 GVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAAGQAG 181
            + +AG   E    GV   A   G+  E   +G+  A G  G
Sbjct: 356 ELGEAGPSGE---PGVPGDAGMPGERGEAGHRGSAGALGPQG 394



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 38/168 (22%), Positives = 60/168 (35%), Gaps = 9/168 (5%)

Query: 51  LDGINSGITHAGREVEKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGI-GQAG 109
           LDG        G   EK  NGL  +    G + +KG +G    + +       G+ G AG
Sbjct: 314 LDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAG 373

Query: 110 KEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKL 169
              E+   G   +AG  G +      G        G + +K   G        G   +  
Sbjct: 374 MPGERGEAGHRGSAGALGPQGPPGAPGVR------GFQGQKGSMGDPGLPGPQGLRGDVG 427

Query: 170 GQGAHHAAGQAGKELQNAHNGV--NQASKEANQLLNGNHQSGSSSHQG 215
            +G   AAG  G +     +G+  ++     + L+    +SGS    G
Sbjct: 428 DRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELG 475



 Score = 28.1 bits (61), Expect = 7.4
 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 4/98 (4%)

Query: 118 GVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEKLGQGAHHAA 177
           G+  A G+AG   ++  +GF       G+   K   GV   + + G   +    G     
Sbjct: 256 GIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLD 315

Query: 178 GQAGKELQNAHNGVNQASKEANQLLNGNHQSGSSSHQG 215
           GQ G+  +N   G     K  N L     ++GS   +G
Sbjct: 316 GQKGEAGRNGAPG----EKGPNGLPGLPGRAGSKGEKG 349



 Score = 27.7 bits (60), Expect = 9.6
 Identities = 20/87 (22%), Positives = 33/87 (37%)

Query: 105 IGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGK 164
           +G+ G +      G +   G  GK+    V G      +AG+      +G N      G+
Sbjct: 282 LGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGR 341

Query: 165 EVEKLGQGAHHAAGQAGKELQNAHNGV 191
              K  +G    AG+ G+   +   GV
Sbjct: 342 AGSKGEKGERGRAGELGEAGPSGEPGV 368


>gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]
          Length = 1016

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 37/152 (24%), Positives = 58/152 (38%), Gaps = 7/152 (4%)

Query: 8   GSC-SLLLLLGALSGWAASDDPIEKVIEGINRGLSNAEREVGKALDGINSGITHAGREVE 66
           G C SL   LG L G     D +   ++G+  GLS     +   L   N+        +E
Sbjct: 718 GQCPSLEGRLGRLEGVCERLDTVAGGLQGLREGLSRHVAGLWAGLRETNTTSQMQAALLE 777

Query: 67  KVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQA 126
           K+  G + +G   G  L+  +Q L   + +++  +    G AG+       G+    G A
Sbjct: 778 KLVGGQAGLGRRLG-ALNSSLQLLEDRLHQLS--LKDLTGPAGEAGPPGPPGLQGPPGPA 834

Query: 127 GKEADKAVQGFHTGVHQAGKEAEKLGQGVNHA 158
           G        G    +   G + E   QGV  A
Sbjct: 835 GPPGSPGKDGQEGPIGPPGPQGE---QGVEGA 863


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 1/80 (1%)

Query: 104 GIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAG 163
           GIG  G      G G    +G  G + +K   GF  G+   G + +K  QG+     Q+G
Sbjct: 800 GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGF-PGLDMPGPKGDKGAQGLPGITGQSG 858

Query: 164 KEVEKLGQGAHHAAGQAGKE 183
                  QGA    G  G +
Sbjct: 859 LPGLPGQQGAPGIPGFPGSK 878



 Score = 27.7 bits (60), Expect = 9.6
 Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 5/83 (6%)

Query: 104  GIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQGFH-----TGVHQAGKEAEKLGQGVNHA 158
            G+G  G   EK   G+    G  G   DK  +G        G+   G   EK  QG+   
Sbjct: 1015 GMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGF 1074

Query: 159  ADQAGKEVEKLGQGAHHAAGQAG 181
                G++ EK   G     G  G
Sbjct: 1075 PGSPGEKGEKGSIGIPGMPGSPG 1097


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 81  KELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQG 136
           ++L  G +GL+     V  E  +G+   G E  K G    NAAG  G+ A+ +  G
Sbjct: 594 EDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHG 649


>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
           sapiens]
          Length = 780

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 18/56 (32%), Positives = 27/56 (48%)

Query: 81  KELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQAGKEADKAVQG 136
           ++L  G +GL+     V  E  +G+   G E  K G    NAAG  G+ A+ +  G
Sbjct: 594 EDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHG 649


>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
          Length = 1088

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 2/75 (2%)

Query: 109 GKEAEKLGHGVNNAAGQAGKEADKAVQGFHTGVHQAGKEAEKLGQGVNHAADQAGKEVEK 168
           G+EA  +  G        G+EA+ A  G   G    G+EA     G   A   +G E   
Sbjct: 298 GEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGG--EAGTASGGEEAG 355

Query: 169 LGQGAHHAAGQAGKE 183
              G   A   +GKE
Sbjct: 356 TASGGDEAWTTSGKE 370


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score = 30.0 bits (66), Expect = 1.9
 Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 24/146 (16%)

Query: 66   EKVFNGLSNMGSHTGKELDKGVQGLNHGMDKVAHEINHGIGQAGKEAEKLGHGVNNAAGQ 125
            ++  N ++N G H  K ++  +  LNH    ++H I     + GK +  L          
Sbjct: 1728 DQAANLMANRGDHCRKLVEPQISELNHRFAAISHRI-----KTGKASIPL---------- 1772

Query: 126  AGKEADKAVQGFHTGVHQAGKEAE-KLGQGVNHAADQAGKEVEKLGQGAHHAAGQAGKEL 184
                  K ++ F++ + +  +  E ++ QGVN   +   K++ +  +G      Q G  L
Sbjct: 1773 ------KELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNL 1826

Query: 185  QN--AHNGVNQASKEANQLLNGNHQS 208
            Q         +  K   QLL   H +
Sbjct: 1827 QQRITDERKREEIKIKQQLLQTKHNA 1852


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,055,130
Number of Sequences: 37866
Number of extensions: 398574
Number of successful extensions: 1729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 1368
Number of HSP's gapped (non-prelim): 260
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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