Guide to the Human Genome
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Name: PTPLB Sequence: fasta or formatted (254aa) NCBI GI: 38257153
Description:

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
Fatty Acid Synthesis
Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.8         25           3
 C cysteine            0.4          1           1
 D aspartate           1.2          3           1
 E glutamate           3.5          9           2
 F phenylalanine       5.9         15           2
 G glycine             7.5         19           5
 H histidine           3.1          8           1
 I isoleucine          8.7         22           2
 K lysine              5.1         13           3
 L leucine            11.4         29           2
 M methionine          2.4          6           1
 N asparagine          2.0          5           1
 P proline             3.9         10           1
 Q glutamine           2.4          6           1
 R arginine            3.5          9           2
 S serine              7.5         19           2
 T threonine           5.1         13           1
 V valine              7.9         20           2
 W tryptophan          1.6          4           1
 Y tyrosine            7.1         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   protein tyrosine phosphatase-like (proline instead o... 
PTPLA                 0.622   protein tyrosine phosphatase-like, member A 
PTPLAD1               0.178   protein tyrosine phosphatase-like A domain containi...
PTPLAD2               0.154   protein tyrosine phosphatase-like A domain containi...
ABCA5                 0.023   ATP-binding cassette, sub-family A , member 5 
ABCA5                 0.023   ATP-binding cassette, sub-family A , member 5 
CCDC85C               0.019   coiled-coil domain containing 85C 
CECR6                 0.019   cat eye syndrome chromosome region, candidate 6 isof...
RAVER2                0.017   ribonucleoprotein, PTB-binding 2 
EN1                   0.017   engrailed homeobox 1 
DACH1                 0.017   dachshund homolog 1 isoform b 
DACH1                 0.017   dachshund homolog 1 isoform a 
DACH1                 0.017   dachshund homolog 1 isoform c 
SAP30                 0.015   Sin3A-associated protein, 30kDa 
INTS3                 0.015   integrator complex subunit 3 
ARID1B                0.015   AT rich interactive domain 1B (SWI1-like) isoform 2 ...
ARID1B                0.015   AT rich interactive domain 1B (SWI1-like) isoform 1 ...
ARID1B                0.015   AT rich interactive domain 1B (SWI1-like) isoform 3 ...
EVX2                  0.015   even-skipped homeobox 2 
RFX1                  0.012   regulatory factor X1 
ZIC2                  0.012   zinc finger protein of the cerebellum 2 
XYLT1                 0.012   xylosyltransferase I 
FBL                   0.012   fibrillarin 
GBX1                  0.012   gastrulation brain homeo box 1 
KCNN2                 0.012   small conductance calcium-activated potassium channe...
FBXO28                0.010   F-box protein 28 isoform b 
FBXO28                0.010   F-box protein 28 isoform a 
FOXD1                 0.010   forkhead box D1 
EMP1                  0.010   epithelial membrane protein 1 
MEGF9                 0.010   multiple EGF-like-domains 9 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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