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Search of human proteins with 38201627
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
(1512 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 3010 0.0
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 3010 0.0
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 3010 0.0
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 2849 0.0
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 1259 0.0
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 196 1e-49
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 196 1e-49
gi|33386693 poly(A) binding protein interacting protein 1 isofor... 81 9e-15
gi|17511255 poly(A) binding protein interacting protein 1 isofor... 81 9e-15
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 1e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni... 79 3e-14
gi|169212085 PREDICTED: similar to poly(A) binding protein inter... 78 7e-14
gi|239752553 PREDICTED: similar to poly(A) binding protein inter... 78 7e-14
gi|89041275 PREDICTED: similar to poly(A) binding protein intera... 78 7e-14
gi|34452730 poly(A) binding protein interacting protein 1 isofor... 77 1e-13
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 76 2e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 75 4e-13
gi|116284392 mucin 2 precursor [Homo sapiens] 72 4e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 4e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 4e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 71 9e-12
gi|110349719 titin isoform N2-A [Homo sapiens] 70 2e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 69 3e-11
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 69 3e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 68 6e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 68 8e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 68 8e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 68 8e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 68 8e-11
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 3010 bits (7804), Expect = 0.0
Identities = 1512/1512 (100%), Positives = 1512/1512 (100%)
Query: 1 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 60
MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP
Sbjct: 88 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 147
Query: 61 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 120
AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT
Sbjct: 148 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 207
Query: 121 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 180
PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS
Sbjct: 208 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 267
Query: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV
Sbjct: 268 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 327
Query: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP
Sbjct: 328 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 387
Query: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS
Sbjct: 388 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 447
Query: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420
ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV
Sbjct: 448 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 507
Query: 421 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 480
AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP
Sbjct: 508 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 567
Query: 481 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 540
EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM
Sbjct: 568 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 627
Query: 541 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 600
QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG
Sbjct: 628 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 687
Query: 601 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 660
PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR
Sbjct: 688 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 747
Query: 661 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 720
GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS
Sbjct: 748 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 807
Query: 721 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 780
EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE
Sbjct: 808 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 867
Query: 781 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 840
MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH
Sbjct: 868 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 927
Query: 841 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 900
DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG
Sbjct: 928 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 987
Query: 901 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 960
SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV
Sbjct: 988 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 1047
Query: 961 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1020
DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD
Sbjct: 1048 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1107
Query: 1021 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1080
AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG
Sbjct: 1108 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1167
Query: 1081 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1140
GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL
Sbjct: 1168 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1227
Query: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1200
PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL
Sbjct: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1287
Query: 1201 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1260
ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI
Sbjct: 1288 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1347
Query: 1261 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1320
LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL
Sbjct: 1348 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1407
Query: 1321 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1380
PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN
Sbjct: 1408 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1467
Query: 1381 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1440
LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA
Sbjct: 1468 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1527
Query: 1441 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1500
LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK
Sbjct: 1528 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1587
Query: 1501 WLREAEEESDHN 1512
WLREAEEESDHN
Sbjct: 1588 WLREAEEESDHN 1599
Score = 33.5 bits (75), Expect = 1.6
Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)
Query: 172 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 227
P S P P+PSP L + P PG T + + + +TP R+ P R
Sbjct: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57
Query: 228 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
P P+ A + P S+ P Q P + I G S
Sbjct: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113
Query: 283 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 330
+ P + + P P SP P ++ G AP+P ++ P
Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173
Query: 331 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 374
+ +P + K++T + + PT P P A Q + +
Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233
Query: 375 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 431
+ +G A G E E P +P P+ S LE + +AV S+P
Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292
Query: 432 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 485
+++ +E+ G+ E P + S P PESE S P +A
Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349
Query: 486 TWDSKEDKIHNAENIQPGE 504
S +IH + P E
Sbjct: 350 PLASHTVEIHEPNGMVPSE 368
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 3010 bits (7804), Expect = 0.0
Identities = 1512/1512 (100%), Positives = 1512/1512 (100%)
Query: 1 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 60
MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP
Sbjct: 1 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 60
Query: 61 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 120
AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT
Sbjct: 61 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 120
Query: 121 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 180
PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS
Sbjct: 121 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 180
Query: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV
Sbjct: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
Query: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP
Sbjct: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
Query: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS
Sbjct: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
Query: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420
ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV
Sbjct: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420
Query: 421 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 480
AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP
Sbjct: 421 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 480
Query: 481 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 540
EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM
Sbjct: 481 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 540
Query: 541 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 600
QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG
Sbjct: 541 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 600
Query: 601 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 660
PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR
Sbjct: 601 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 660
Query: 661 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 720
GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS
Sbjct: 661 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 720
Query: 721 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 780
EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE
Sbjct: 721 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 780
Query: 781 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 840
MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH
Sbjct: 781 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 840
Query: 841 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 900
DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG
Sbjct: 841 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 900
Query: 901 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 960
SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV
Sbjct: 901 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 960
Query: 961 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1020
DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD
Sbjct: 961 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1020
Query: 1021 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1080
AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG
Sbjct: 1021 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1080
Query: 1081 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1140
GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL
Sbjct: 1081 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1140
Query: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1200
PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL
Sbjct: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1200
Query: 1201 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1260
ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI
Sbjct: 1201 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1260
Query: 1261 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1320
LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL
Sbjct: 1261 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1320
Query: 1321 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1380
PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN
Sbjct: 1321 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1380
Query: 1381 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1440
LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA
Sbjct: 1381 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1440
Query: 1441 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1500
LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK
Sbjct: 1441 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1500
Query: 1501 WLREAEEESDHN 1512
WLREAEEESDHN
Sbjct: 1501 WLREAEEESDHN 1512
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 3010 bits (7804), Expect = 0.0
Identities = 1512/1512 (100%), Positives = 1512/1512 (100%)
Query: 1 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 60
MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP
Sbjct: 88 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 147
Query: 61 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 120
AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT
Sbjct: 148 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 207
Query: 121 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 180
PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS
Sbjct: 208 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 267
Query: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV
Sbjct: 268 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 327
Query: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP
Sbjct: 328 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 387
Query: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS
Sbjct: 388 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 447
Query: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420
ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV
Sbjct: 448 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 507
Query: 421 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 480
AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP
Sbjct: 508 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 567
Query: 481 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 540
EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM
Sbjct: 568 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 627
Query: 541 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 600
QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG
Sbjct: 628 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 687
Query: 601 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 660
PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR
Sbjct: 688 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 747
Query: 661 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 720
GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS
Sbjct: 748 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 807
Query: 721 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 780
EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE
Sbjct: 808 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 867
Query: 781 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 840
MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH
Sbjct: 868 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 927
Query: 841 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 900
DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG
Sbjct: 928 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 987
Query: 901 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 960
SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV
Sbjct: 988 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 1047
Query: 961 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1020
DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD
Sbjct: 1048 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1107
Query: 1021 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1080
AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG
Sbjct: 1108 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1167
Query: 1081 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1140
GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL
Sbjct: 1168 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1227
Query: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1200
PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL
Sbjct: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1287
Query: 1201 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1260
ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI
Sbjct: 1288 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1347
Query: 1261 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1320
LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL
Sbjct: 1348 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1407
Query: 1321 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1380
PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN
Sbjct: 1408 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1467
Query: 1381 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1440
LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA
Sbjct: 1468 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1527
Query: 1441 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1500
LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK
Sbjct: 1528 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1587
Query: 1501 WLREAEEESDHN 1512
WLREAEEESDHN
Sbjct: 1588 WLREAEEESDHN 1599
Score = 33.5 bits (75), Expect = 1.6
Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)
Query: 172 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 227
P S P P+PSP L + P PG T + + + +TP R+ P R
Sbjct: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57
Query: 228 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
P P+ A + P S+ P Q P + I G S
Sbjct: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113
Query: 283 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 330
+ P + + P P SP P ++ G AP+P ++ P
Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173
Query: 331 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 374
+ +P + K++T + + PT P P A Q + +
Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233
Query: 375 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 431
+ +G A G E E P +P P+ S LE + +AV S+P
Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292
Query: 432 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 485
+++ +E+ G+ E P + S P PESE S P +A
Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349
Query: 486 TWDSKEDKIHNAENIQPGE 504
S +IH + P E
Sbjct: 350 PLASHTVEIHEPNGMVPSE 368
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 2849 bits (7386), Expect = 0.0
Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)
Query: 78 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 137
MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP
Sbjct: 1 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60
Query: 138 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 197
QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS
Sbjct: 61 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
Query: 198 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 257
IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP
Sbjct: 121 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180
Query: 258 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 317
LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL
Sbjct: 181 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
Query: 318 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 377
NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE
Sbjct: 241 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300
Query: 378 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 437
EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK
Sbjct: 301 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360
Query: 438 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 497
EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA
Sbjct: 361 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420
Query: 498 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 557
ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA
Sbjct: 421 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480
Query: 558 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 617
NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS
Sbjct: 481 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540
Query: 618 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 677
QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV
Sbjct: 541 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
Query: 678 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 737
RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA
Sbjct: 601 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
Query: 738 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 797
LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL
Sbjct: 661 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720
Query: 798 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 857
EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK
Sbjct: 721 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780
Query: 858 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 917
DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ
Sbjct: 781 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840
Query: 918 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 977
IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI
Sbjct: 841 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900
Query: 978 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 1037
DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS
Sbjct: 901 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960
Query: 1038 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1097
ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR
Sbjct: 961 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020
Query: 1098 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1157
SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK
Sbjct: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080
Query: 1158 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1217
KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL
Sbjct: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140
Query: 1218 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1277
LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK
Sbjct: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200
Query: 1278 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1337
PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY
Sbjct: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260
Query: 1338 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1397
TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT
Sbjct: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320
Query: 1398 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1457
AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM
Sbjct: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380
Query: 1458 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1512
FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 2784 bits (7218), Expect = 0.0
Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)
Query: 110 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 169
MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
Query: 170 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 229
SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
Query: 230 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 289
PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
Query: 290 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 349
SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
Query: 350 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 409
IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
Query: 410 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 469
QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
Query: 470 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 529
ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
Query: 530 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 589
LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
Query: 590 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649
TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
Query: 650 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709
SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
Query: 710 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 769
VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
Query: 770 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 829
DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
Query: 830 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 889
HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
Query: 890 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 949
FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
Query: 950 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1009
GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
Query: 1010 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1069
SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
Query: 1070 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1129
RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
Query: 1130 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1189
GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
Query: 1190 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1249
IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
Query: 1250 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1309
WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
Query: 1310 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1369
REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
Query: 1370 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1429
NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
Query: 1430 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1489
DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
Query: 1490 VALKSVTAFFKWLREAEEESDHN 1512
VALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 VALKSVTAFFKWLREAEEESDHN 1403
>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
sapiens]
Length = 1585
Score = 1259 bits (3258), Expect = 0.0
Identities = 788/1609 (48%), Positives = 978/1609 (60%), Gaps = 186/1609 (11%)
Query: 9 YPASQGAYYIPGQGRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQG 63
YP QG Y Q R + YV P QQYPVQP PG FYPG P +F Y +YP+Q
Sbjct: 58 YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP 117
Query: 64 VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA---------- 113
V Q + P QPP KRE+KTIRIRDPNQGGKDITEEIMSG
Sbjct: 118 VYQSAPIIVPT---QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172
Query: 114 RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 173
R STPTPPQ L Q +P V V + A +A + E +P
Sbjct: 173 RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223
Query: 174 SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 215
SPSPVL E + ++A L +P T++++ S +
Sbjct: 224 PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283
Query: 216 ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 262
S + +P SP + P L S P+P +E + P
Sbjct: 284 SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343
Query: 263 ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 318
PL S T I+E NG+ SE L ES E+ P + I E L
Sbjct: 344 PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
Query: 319 GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 374
P+P ++P + P T +PP P PA A + +SP+ + +EE+E
Sbjct: 401 CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456
Query: 375 E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 423
E+ E E E++ EE+L ++ +P+PA Q+A++
Sbjct: 457 SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504
Query: 424 VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 479
VPK +K K+ + +E + L+ E ++ +V + G PE + S + +
Sbjct: 505 VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563
Query: 480 PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 524
+ +E + E + AE++ GE + +K + WKP + E KK+
Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623
Query: 525 YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 582
YDREFLL FQF+ A +QKPEGLP ISDVVLDK N K P+R LDP L GPDFTP+
Sbjct: 624 YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680
Query: 583 FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 642
FA+ GR T RG P +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 681 FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728
Query: 643 AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 702
AE AWKPS KR D +D + KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 729 AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783
Query: 703 TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 762
TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP +KP TVNFRKLLLNRCQK
Sbjct: 784 TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843
Query: 763 EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 822
EFEKDK DD+VFEKKQKE++ A+ EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 844 EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903
Query: 823 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 882
MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 904 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963
Query: 883 KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 942
KTSSRIRFMLQDV+DLR NWV RR DQGPKTI+QIHKEA++EE E KVQQLM K +
Sbjct: 964 KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021
Query: 943 KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 1002
KRR G+ VD+GGWNTV +K SR +D S+ KITKP +ID QL
Sbjct: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071
Query: 1003 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 1054
SWGKGSSGG+ A +D A R + S+LNRFSALQ P+ ST D+RR +
Sbjct: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127
Query: 1055 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1113
R S+ RE+ +K R RGG D LD ++ EE+ RE
Sbjct: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176
Query: 1114 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1169
+ L + + RE+A P +S + KAALSEEELE+KSK+II+E+LH+
Sbjct: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236
Query: 1170 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1229
ND KEA+QCV+EL + LL +FVR GVESTLERS I R+HMGQLL+QL+ + LS ++
Sbjct: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296
Query: 1230 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1289
+G E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL E +KPL P+G+A LL
Sbjct: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356
Query: 1290 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1346
EIL LLCK M KKVG LWREA LSWK+FLPEG+D+ F+ EQK+++ + SEA
Sbjct: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416
Query: 1347 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1405
++ L +EEL ++LEKL+ E +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476
Query: 1406 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1463
+ + RVD AV+K R +L KYL D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536
Query: 1464 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1512
DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
isoform 2 [Homo sapiens]
Length = 869
Score = 196 bits (498), Expect = 1e-49
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 620 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 676
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
Query: 677 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 736
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
Query: 737 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 788
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
Query: 789 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 842
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
Query: 843 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 901
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
Query: 902 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 952
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
Score = 113 bits (282), Expect = 2e-24
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1199
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 492 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 551
Query: 1200 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1259
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 552 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 611
Query: 1260 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1319
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 612 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 666
Query: 1320 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1378
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 667 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 717
Query: 1379 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1423
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 718 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777
Query: 1424 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1482
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 778 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 836
Query: 1483 AEQQGKGVALKSVTAFFKWLREAEEE 1508
E GKG AL V + WL AEEE
Sbjct: 837 QEFPGKGKALFQVNQWLTWLETAEEE 862
>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
Length = 907
Score = 196 bits (498), Expect = 1e-49
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 620 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 676
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
Query: 677 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 736
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
Query: 737 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 788
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
Query: 789 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 842
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
Query: 843 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 901
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
Query: 902 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 952
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
Score = 113 bits (282), Expect = 2e-24
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1199
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
Query: 1200 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1259
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
Query: 1260 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1319
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
Query: 1320 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1378
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
Query: 1379 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1423
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
Query: 1424 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1482
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
Query: 1483 AEQQGKGVALKSVTAFFKWLREAEEE 1508
E GKG AL V + WL AEEE
Sbjct: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
>gi|33386693 poly(A) binding protein interacting protein 1 isoform 2
[Homo sapiens]
Length = 400
Score = 80.9 bits (198), Expect = 9e-15
Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)
Query: 614 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 673
P+++ + +P+ ++A VLM++ + +N E S + G ED L
Sbjct: 26 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 79
Query: 674 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 728
V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS
Sbjct: 80 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 139
Query: 729 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 788
A +C L + + NFR+LLL RC+ E+E
Sbjct: 140 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 172
Query: 789 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 836
+K++ + ++ R+R + F+GEL+ L++ + + + + + L
Sbjct: 173 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 228
Query: 837 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 893
N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML
Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288
Query: 894 DVLDLRGSNW 903
+++LR SNW
Sbjct: 289 KLVELRSSNW 298
>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
[Homo sapiens]
Length = 479
Score = 80.9 bits (198), Expect = 9e-15
Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)
Query: 614 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 673
P+++ + +P+ ++A VLM++ + +N E S + G ED L
Sbjct: 105 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 158
Query: 674 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 728
V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS
Sbjct: 159 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 218
Query: 729 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 788
A +C L + + NFR+LLL RC+ E+E
Sbjct: 219 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 251
Query: 789 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 836
+K++ + ++ R+R + F+GEL+ L++ + + + + + L
Sbjct: 252 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 307
Query: 837 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 893
N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML
Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367
Query: 894 DVLDLRGSNW 903
+++LR SNW
Sbjct: 368 KLVELRSSNW 377
Score = 31.6 bits (70), Expect = 6.1
Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 20/123 (16%)
Query: 274 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 316
PNG P+E L+P P PPP E P P P A PE+
Sbjct: 32 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQT 91
Query: 317 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT---PATAPSATSPAQEEEMEEE 373
P + D P E + +AP + + P PS S + E E+
Sbjct: 92 RPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDG 151
Query: 374 EEE 376
E+
Sbjct: 152 CED 154
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 80.1 bits (196), Expect = 1e-14
Identities = 90/344 (26%), Positives = 129/344 (37%), Gaps = 35/344 (10%)
Query: 30 TQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRE 89
TQ P P P SP A PA Q T ++PA ++ P I P +
Sbjct: 437 TQASLTSPSRPASTPPDSPP---LQAPLSLPASPPLQ--TSLSPAVSPLSSPLTIHPLQA 491
Query: 90 RKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRS 149
++ P ++ IM T S+ PP +TP ++ P +
Sbjct: 492 LSSLASHSPQA---PLSSLIMPPLETQSSLAPPSL----------QTPPASLTTPPLENL 538
Query: 150 QGAIIADRPGLPGPEHSPSESQPSSPSPTP---SPSPVLEPGSEPNLAVLSIPGDTMTTI 206
P +P P P+P P PSP+ P E ++ + P +
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598
Query: 207 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 266
S P+ P P P A P L + + P P + SPL P+P A
Sbjct: 599 A-----SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
Query: 267 HTVEIH---EPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSP 323
+ + +H P PS ++ SP A PP PS +P AP + L PSP
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPF--SPP-ASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 324 PAVD-LSPVSEPEEQAKEVTAS--MAPPTIPSATPATAPSATSP 364
PA +SP + P QA A+ + P P A+P +PSAT P
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 73.6 bits (179), Expect = 1e-12
Identities = 84/299 (28%), Positives = 117/299 (39%), Gaps = 29/299 (9%)
Query: 71 VAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD-ITEEIMSGARTASTPTPPQTGGGLE 129
+AP P+ P P E P Q +T + +TP P
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
Query: 130 PQANG-ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPG 188
P G +P ++ + P ++ + P L P SP S P SP TPSP
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALA 657
Query: 189 SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPV 248
A S P S S P+S P S P LA P L+V +
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASP 714
Query: 249 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 308
P S ++ P QAP PLA+ +++ PS P + SP PPP P P+ A
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVP------PSPPASPPM--SPSATPPPRVP---PLLAA 763
Query: 309 PTAQPEELLNGAPSPPA-VDLSPVSEPEEQAKEVTAS---MAPPTIPSATPATAPSATS 363
P Q PSPPA + +SP+++P QA A+ A P+ P++ P AP + S
Sbjct: 764 PPLQVP------PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Score = 67.4 bits (163), Expect = 1e-10
Identities = 92/381 (24%), Positives = 131/381 (34%), Gaps = 60/381 (15%)
Query: 34 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAP--APVLMNQPPQIAPKRERK 91
P+ P P A+P + + P+ P P AP M PP AP
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP---- 381
Query: 92 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVA-----VIVRPD 146
+++ P Q +T + P P L+ + +P + + + P
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQA------PPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
Query: 147 DRSQGAIIADRPGLPGPEHSPSE---SQPSSPSPTPSPSPVLEPGSEP----NLAVLSIP 199
RP P+ P + S P+SP S SP + P S P L LS
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495
Query: 200 GDTMTTIQMSVEESTPISRETG-EPYRLSPEPTPLAEPILEVEVTL--------SKPVPE 250
+S P+ ++ P L P L P LE +L S P+
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555
Query: 251 SEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA----CPSESPVP 306
+ P AP PL + + P PS P ++ P LA PP P SP+
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615
Query: 307 IAPTAQPEEL----LNGAPSPPAVD-LSPVSEPEEQAKE------------------VTA 343
P P L L PSPPA LSP++ P QA V A
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675
Query: 344 SMAPPTIPSATPATAPSATSP 364
+PP P +P+ P + +P
Sbjct: 676 PFSPPASPPVSPSATPPSQAP 696
Score = 58.5 bits (140), Expect = 5e-08
Identities = 78/335 (23%), Positives = 122/335 (36%), Gaps = 35/335 (10%)
Query: 47 SPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP----PQIAPKRERKTIRIRDPNQGG 102
+P AGA G PT P+P + + ++ R + R R P +G
Sbjct: 150 APKRSALSAGARRDTSG----PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
Query: 103 KDITEEIMSGARTASTPTP---PQTGGGLEPQANGETPQVAVIVRPDDRS----QGAIIA 155
+ + T +P P GGGL+ A+ A + RS +G A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 156 D-RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST 214
P P P+ + P P +P L P S LA S G + +T
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325
Query: 215 PISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEP 274
P+ P L P P PLA P+ L+ P P + S L P+P A+ + P
Sbjct: 326 PL------PATLPPSP-PLATPL-----PLAPPSPSAPPSLQTL--PSPPATPPSQA-PP 370
Query: 275 NGMVPSEDLEPEVESSPELAPPPACPSES----PVPIAPTAQPEELLNGAPSPPAVDLSP 330
+ P P +++ P + P + S S P P+A ++ G+P+ A
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430
Query: 331 VSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 365
P + +T+ P + P +P + PA
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Score = 49.3 bits (116), Expect = 3e-05
Identities = 94/419 (22%), Positives = 132/419 (31%), Gaps = 44/419 (10%)
Query: 29 PTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKR 88
P Q P P +P P A+P+ A A + + Q P P+P + Q P P
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVH----LLQAPFSPPPSPPV--QAPFSPPAS 682
Query: 89 ERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVR---- 144
+ P+Q + + S P P P P A ++
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 145 -PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTM 203
P P +P +P P SP + SP+ +P + A+ + P +
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 204 TTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP-- 261
+ S P S P P P A P+L + VP S +S LQAP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRR 857
Query: 262 TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 318
P + P + P P S L+ P S + T+ PEE L
Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LR 912
Query: 319 GAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEEM 370
G S P SP + E A A P P A P P AT P + +
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972
Query: 371 EEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 429
E E E+ + G P P A A + PK+ R
Sbjct: 973 CTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 48.1 bits (113), Expect = 6e-05
Identities = 82/337 (24%), Positives = 113/337 (33%), Gaps = 50/337 (14%)
Query: 40 PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP-PQIAPKRERKTIRIRDP 98
P P A PT + PA G P P P +P R T R
Sbjct: 71 PESAPRAGPTR-SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 99 NQGGKDIT-EEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADR 157
Q G I+ EE ++ + P G +G TP P +
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPAMARRSRAAGTE 186
Query: 158 PGLPGPEHSPSESQPSSPSPTPSPSPVLEPGS-EPNLAVLSIPGDTMTTIQMSVEESTPI 216
GLP P S + +P + P S S E + EP+ A P P
Sbjct: 187 VGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS-------AGGGLQRPA 238
Query: 217 SRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNG 276
SR LS TPL+ P S P TP A +P G
Sbjct: 239 SRS------LSSSATPLSSPA----------------RSGPSARGTPRAPAHPSQPKPKG 276
Query: 277 MV---PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 333
+ P + P +++P L P + P +P P A+P + A +P P +
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP-----LPATL 331
Query: 334 PEEQAKEVTASMAPPTIPSATPA----TAPSATSPAQ 366
P +APP+ PSA P+ +P AT P+Q
Sbjct: 332 PPSPPLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQ 367
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 79.0 bits (193), Expect = 3e-14
Identities = 115/468 (24%), Positives = 163/468 (34%), Gaps = 88/468 (18%)
Query: 34 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 93
P GAP P+ G A +G P P+P P +PK T
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGLATP--SPKGAPTTP 1244
Query: 94 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 153
P+ G T GA T TPP GGL + P AV+ P +
Sbjct: 1245 AATPPSPKGGPATPP-PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG---- 1299
Query: 154 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 213
GP SP + P+ P+ TP PSP PG+ P + P T
Sbjct: 1300 --------GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVT----------- 1339
Query: 214 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 273
P+P P L SK P + S + PTP A+
Sbjct: 1340 ---------------PPSPKGTPTLPATTPSSKGGPTTPSSK---EGPTPPAATPSHKGG 1381
Query: 274 PNGMVPSEDLEPEVESSPELAPPPACP-SESPVPIAPTAQPEELL--NGAPSPPAVDLSP 330
P M P P + P + P P S + +P++P P + GA +P DL+P
Sbjct: 1382 P-AMTP-----PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 331 VSEPEEQAKEVTASMAP---PTIPSAT-PATAPSATSPAQEEEMEEEEEEEEGEAGEAGE 386
+ K+ A+ AP P PS+ T P+ T P+ +E ++ +A
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Query: 387 AESEKGGEEL---LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDL 443
+ G L +P +PA S + A T +S ++ L KEA+
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS----KKTPATLAPKEAL--- 1548
Query: 444 LDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKE 491
PPA + P P+ + P P+EA T SKE
Sbjct: 1549 ----------------IPPAMTVPSPKK--TPAIPTPKEAPATPSSKE 1578
Score = 65.9 bits (159), Expect = 3e-10
Identities = 117/524 (22%), Positives = 176/524 (33%), Gaps = 102/524 (19%)
Query: 35 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIR 94
V P +P P SP + GA P P G P PP+ AP
Sbjct: 1292 VTPPSPKGGPATSPPK-----GAPTPPAATPPSPKGSPGTP-----PPKGAPTPPA---- 1337
Query: 95 IRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQAN-GETPQVAVIVRPDDRSQGAI 153
+T G T TP GG P + G TP A P + A+
Sbjct: 1338 ----------VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---PSHKGGPAM 1384
Query: 154 IADRP----GLPGPEHSPSESQ--PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQ 207
P +P P+ P+ P SP P+ E + P+ L+ P T +++
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 208 MSVEESTP-----ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT 262
+ S P G+P + P EP +V S ++ + +P+ APT
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 263 ---------------------PLASHTVEIHE--PNGMVPSEDLEPEVESSPELAPPPAC 299
P+A + + P + P E L P + P PA
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564
Query: 300 PSESPVPIAPTAQPEE--------LLNGAPSPPAVDLSP-VSEPEEQAKEVTASMAPPTI 350
P+ P P+++ GAPSP + + P V+ P + ++ PP+
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 351 PS--ATPATAPSATSPAQEEEMEEEEEEEEGE--------AGEAGEAESEKGGEELL--- 397
ATPA + TSP ++ +A + K G L
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
Query: 398 ----PPESTPI---PANLSQNLEAAAATQVAVSV-PKRRRKIKELNKKEAVGDLLDAFKE 449
PESTPI P + ++AT + P + K A LL K+
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744
Query: 450 AN-PAVPEVENQPPAGSNPGPESEGS---------GVPPRPEEA 483
++ A + + P G PES+ S V P+PE A
Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Score = 65.1 bits (157), Expect = 5e-10
Identities = 102/412 (24%), Positives = 138/412 (33%), Gaps = 56/412 (13%)
Query: 100 QGGKDI-------TEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 152
QG KD T GA T S TP G P TP V + P +
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 153 IIADRPGLPGPEHSPSESQ--------PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 204
P L SP +++ P+SPSP +P+P P P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK----GGPATPSP 959
Query: 205 TIQMSVEESTPISRETGEPYRLSPE--PTPLAEPILEVEVTLSKPVPE-SEFSSSPLQAP 261
+ +TP S + G P SP+ PTP A + P P+ + SP AP
Sbjct: 960 KWAPTPPAATPPSPK-GGPATPSPKGAPTPPA---------ATPPSPKGGPATPSPKGAP 1009
Query: 262 TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELL- 317
TP A V P G P+ P+ S+P A PP+ P+ +P+P P L
Sbjct: 1010 TPPA---VTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065
Query: 318 --NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 375
G P+ P++ P A + P PS A P A +P +
Sbjct: 1066 SPKGGPATPSLK----GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 376 EEEGEAGEAGEAESEKGGEELLPPESTP-IPANLSQNLEAAAATQVAVSVPKRRRKIKEL 434
+ A S KGG PP+ P PA + + AT PK
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT----PPPKGAPTTPAA 1177
Query: 435 NKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRPE 481
G L + P P P G P +G + PP P+
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Score = 63.5 bits (153), Expect = 1e-09
Identities = 110/490 (22%), Positives = 163/490 (33%), Gaps = 56/490 (11%)
Query: 4 PSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPG--ASPTEFGTYAGAYYPA 61
PS ++ P + P ++ + T P + A G ASP+ GA P
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP----KGAPTPP 943
Query: 62 QGVQQFPTG--VAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTP 119
P G P+P PP P P+ G T GA T
Sbjct: 944 AATPPSPKGGPATPSPKWAPTPPAATP-----------PSPKGGPATPS-PKGAPTPPAA 991
Query: 120 TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 179
TPP GG + P + P + A P P+ + + + PSP
Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA------ATPFPKGASTPPAATPPSPKG 1045
Query: 180 SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES-TPISRETGEPYRLSPEPTPLAEPIL 238
SP+ P P ++P S++ + TP + P P+P P
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP-- 1103
Query: 239 EVEVTLSKPVPESEFSSSPLQ-APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPP 297
+ + P P+ ++ P + APT A+ P G + + P+ + A PP
Sbjct: 1104 -MPPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGLATP--PPKGAPTTPAATPP 1157
Query: 298 ------ACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEEQAKEVTASMAPPT 349
A P P P A P G PSP +P + P +A P+
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----KGGLATPS 1213
Query: 350 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI-PANL 408
P P T P+AT P+ + + + A S KGG PP+ P PA
Sbjct: 1214 -PKGAP-TTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 409 SQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPG 468
+L+ AT P + G + + P P P GS
Sbjct: 1271 PPSLKGGLATPPHKGAPNP----AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 469 PESEGSGVPP 478
P +G+ PP
Sbjct: 1327 PPPKGAPTPP 1336
Score = 45.4 bits (106), Expect = 4e-04
Identities = 76/346 (21%), Positives = 124/346 (35%), Gaps = 40/346 (11%)
Query: 21 QGRSTYVVPTQQYPVQPGAP-----GFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAP 75
+G T T P +P AP P +P PA + P V P
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV-IPSSPKEVPATP 1520
Query: 76 VLMNQPPQIAPKR---ERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQA 132
P IAP +KT P + + S +T + PTP + +
Sbjct: 1521 SSRRDP--IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578
Query: 133 NGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPN 192
P V S ++ P + P SP E+ P+ P+ TP PSP P +
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELLIP-PAVTSP--SPKEA-PTPPAVTP-PSPEKGPATPAP 1633
Query: 193 LAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESE 252
+ P T ++++ S ++ + G + + P + ++ L P PE
Sbjct: 1634 KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE-- 1691
Query: 253 FSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ 312
S+ + APT T + +SP + P P+ + S P++ T
Sbjct: 1692 -STPIITAPTRKGPQT---------------KKSSATSPPICPDPSAKNGSKGPLS-TVA 1734
Query: 313 PEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATA 358
P LL P D S ++ ++ + +APP ++TP TA
Sbjct: 1735 PAPLL-----PVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTA 1775
Score = 41.2 bits (95), Expect = 0.008
Identities = 87/364 (23%), Positives = 134/364 (36%), Gaps = 89/364 (24%)
Query: 155 ADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQM--SVEE 212
AD G+ + + ++ SP + L P + P + T+TT+ + + E
Sbjct: 653 ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP------VKEGTLTTLPLVPTASE 706
Query: 213 STPISRETGEPYRLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSP-----------LQ 259
+ P++ SP+ T PLA +L E+ S P P + +P
Sbjct: 707 NCPVAP--------SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758
Query: 260 APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ----PEE 315
A P+AS E P+ED +S + S SP+ ++ + Q P +
Sbjct: 759 ALAPVASSPKEC-------PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
Query: 316 LLNGAPSPPAVDLS-PVSEPE-----------EQAKEVTASMAPPTIPSATPATAPSATS 363
+ P P +LS PVS E + +K+ A+ PT PS A PSA +
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
Query: 364 PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPA--NLSQNLEAAAATQVA 421
P S KG LPP+ TP P+ NL E A
Sbjct: 872 PL-----------------------SPKG--VTLPPKETPTPSVVNLPFPKEGP-----A 901
Query: 422 VSVPKRRRKIKELNKKEAVGDLLDAFK--EANPAVPEVENQPPAGSNPGPESEGSGVPPR 479
PK+ + + A K A+P+ P+ PPA + P P +G P
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPS-PKGAPTPPAATPPSP--KGGPATPS 958
Query: 480 PEEA 483
P+ A
Sbjct: 959 PKWA 962
Score = 33.1 bits (74), Expect = 2.1
Identities = 70/282 (24%), Positives = 96/282 (34%), Gaps = 78/282 (27%)
Query: 71 VAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEP 130
VAPAP+L Q K KT + +D + K P P P
Sbjct: 1733 VAPAPLLPVQ------KDSSKTAKGKDASHSPKG--------------PLAP-------P 1765
Query: 131 QANGETPQVA-----VIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL 185
++ TP A V+ +P+ S A SP S P +PSP P+ P
Sbjct: 1766 ESKASTPLTAAAFEKVLPKPESASVSAA-----------PSPPVSLPLAPSPVPTLPPKQ 1814
Query: 186 E-PGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTL 244
+ S P L VL P + +E P+ + PEP P V V +
Sbjct: 1815 QFLPSSPGL-VLESPSKPLA--PADEDELLPL---------IPPEPISGGVPFQSVLVNM 1862
Query: 245 SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP 304
P S+ + PTP A V + S+ ES PEL E
Sbjct: 1863 PTP------KSAGIPVPTPSAKQPVTKNNKGSGTESD----SDESVPEL--------EEQ 1904
Query: 305 VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 346
T Q +L A +D PVS+ ++ E A A
Sbjct: 1905 DSTQATTQQAQLAAAA----EIDEEPVSKAKQSRSEKKARKA 1942
>gi|169212085 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 516
Score = 77.8 bits (190), Expect = 7e-14
Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)
Query: 596 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 646
P R P G LP L P+++ + +P+ ++A VL ++ + +N E
Sbjct: 115 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 173
Query: 647 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 701
S + G ED V+ LN LT P F+ ++Q + +
Sbjct: 174 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 228
Query: 702 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 761
T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+
Sbjct: 229 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 284
Query: 762 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 820
E+E +K++ + ++ R+R + F+GEL+
Sbjct: 285 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 317
Query: 821 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 866
L++ + + + + + L N +++L C +LL G L+ EK K
Sbjct: 318 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 377
Query: 867 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 903
M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 378 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 414
>gi|239752553 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 457
Score = 77.8 bits (190), Expect = 7e-14
Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)
Query: 596 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 646
P R P G LP L P+++ + +P+ ++A VL ++ + +N E
Sbjct: 56 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 114
Query: 647 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 701
S + G ED V+ LN LT P F+ ++Q + +
Sbjct: 115 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 169
Query: 702 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 761
T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+
Sbjct: 170 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 225
Query: 762 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 820
E+E +K++ + ++ R+R + F+GEL+
Sbjct: 226 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 258
Query: 821 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 866
L++ + + + + + L N +++L C +LL G L+ EK K
Sbjct: 259 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 318
Query: 867 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 903
M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 319 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 355
>gi|89041275 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 488
Score = 77.8 bits (190), Expect = 7e-14
Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)
Query: 596 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 646
P R P G LP L P+++ + +P+ ++A VL ++ + +N E
Sbjct: 87 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 145
Query: 647 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 701
S + G ED V+ LN LT P F+ ++Q + +
Sbjct: 146 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 200
Query: 702 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 761
T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+
Sbjct: 201 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 256
Query: 762 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 820
E+E +K++ + ++ R+R + F+GEL+
Sbjct: 257 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 289
Query: 821 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 866
L++ + + + + + L N +++L C +LL G L+ EK K
Sbjct: 290 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 349
Query: 867 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 903
M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 350 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 386
>gi|34452730 poly(A) binding protein interacting protein 1 isoform 3
[Homo sapiens]
Length = 367
Score = 77.4 bits (189), Expect = 1e-13
Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 57/300 (19%)
Query: 624 EPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNK 683
+P+ ++A VLM++ + +N E S + G ED L V+ LN
Sbjct: 3 KPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TLSEYVQDFLNH 56
Query: 684 LT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 738
LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS A +C L
Sbjct: 57 LTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHH 116
Query: 739 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 798
+ + NFR+LLL RC+ E+E +K++
Sbjct: 117 LTISPQSG----NFRQLLLQRCRTEYE---------------------------VKDQAA 145
Query: 799 EARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLKNHDEESLE 846
+ ++ R+R + F+GEL+ L++ + + + + + L N +++L
Sbjct: 146 KGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLI 205
Query: 847 CLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 903
C +LL G L+ EK K M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 206 CAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 265
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 76.3 bits (186), Expect = 2e-13
Identities = 96/407 (23%), Positives = 139/407 (34%), Gaps = 71/407 (17%)
Query: 29 PTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTG-----VAPAPVLMNQPPQ 83
P +P G PG + + P GTY+G P Q +Q G VAP P L P
Sbjct: 772 PPSPFPSSTG-PGPHYLSGPLPPGTYSG---PTQLIQPRAPGPHAMPVAPGPALYPAP-- 825
Query: 84 IAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIV 143
A E + P G ++S P PP G P P++A+ V
Sbjct: 826 -AYTPELGLVPRSSPQHG-------VVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAV 877
Query: 144 RPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTM 203
RP + +I A P P +P+ + P P P P P+ P + P A IP
Sbjct: 878 RPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHH 937
Query: 204 TTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTP 263
+ + P R+ P+P P + P P F P Q P P
Sbjct: 938 FSSGIPAGFPAP---------RIGPQPQPHPQ-----------PHPSQAFGPQPPQQPLP 977
Query: 264 LASHTVEIHEPNGMVPSEDLEPEVESSPELAPPP--------ACPSESPVPI-------- 307
L + + G++P + P L PP P++ P+P
Sbjct: 978 LQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFP 1037
Query: 308 --APTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT---IPSATPATAPSAT 362
P P L P+P + P + P +A + P+ +PS P+ P
Sbjct: 1038 SPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPV 1097
Query: 363 SPAQEEEMEEEEEEEEGEA----------GEAGEAESEKGGEELLPP 399
P + E G A + G +S GG+ LL P
Sbjct: 1098 -PPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQP 1143
Score = 32.3 bits (72), Expect = 3.6
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 15/127 (11%)
Query: 232 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 291
P +P+ ++ +P+ L P++S I + + + P LE V S P
Sbjct: 1464 PPCKPLASASISQKNHLPQDS-QDLVLGGDVPISSIQATIAKLS-IRPPGGLESPVASLP 1521
Query: 292 ELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 351
A PP P P + PE + SPP P+S P +A + P P
Sbjct: 1522 GPAEPPGLP--------PASLPESTPIPSSSPP-----PLSSPLPEAPQPKEEPPVPEAP 1568
Query: 352 SATPATA 358
S+ P ++
Sbjct: 1569 SSGPPSS 1575
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 75.5 bits (184), Expect = 4e-13
Identities = 104/403 (25%), Positives = 146/403 (36%), Gaps = 69/403 (17%)
Query: 100 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 159
QGG+ I S +PP+ G + P + G + + +P
Sbjct: 353 QGGQTIRSVAEQHTPVCSRFSPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPK 407
Query: 160 LPGP---EHSPS-----ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 211
PGP E P + +P +P P+L P P + LS P
Sbjct: 408 EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP---PEESPLSPP-----------P 453
Query: 212 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--PLASHTV 269
E +P S E RLSP P L L + LS+P+ ES S P ++P P S
Sbjct: 454 EESPTSPPP-EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512
Query: 270 EIHEPNGMVPSEDLEPEVESSPELAPPP-ACPSESPVPIAPTAQPEELLNGAPSPPAVDL 328
E + + P E+ P L+PPP A P P +P + P E L +P P A L
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572
Query: 329 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATS----PAQEEEMEEEEEEEEGEAGEA 384
SP PEE + M+PP P +P + P S P +E + EE
Sbjct: 573 SP--PPEE------SPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 385 GEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLL 444
S PPE +P+ + + +S P ++ L V L
Sbjct: 623 ASRLSP-------PPEDSPM---------SPPPEESPMSPPPEVSRLSPL----PVVSRL 662
Query: 445 DAFKEANPAVPEVENQP----PAGSNPGPESEGSGVPPRPEEA 483
E +P P E P P S P E S P PE++
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Score = 69.7 bits (169), Expect = 2e-11
Identities = 100/392 (25%), Positives = 139/392 (35%), Gaps = 44/392 (11%)
Query: 118 TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS----PSESQPS 173
T P+ G L+ +A P V+ + + + + + P LP PE S P E P+
Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT 458
Query: 174 SPSPTP---SPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVE-------ESTPISRETGE 222
SP P SP P P S P LS P + E ES+P S
Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518
Query: 223 PYRLSPEPTPLAEPILEVEVT-------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPN 275
P LSP P LE ++ LS P ES S P + PT + P
Sbjct: 519 P--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576
Query: 276 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-- 333
P + P E SP PP A P +P + P E +P P A LSP E
Sbjct: 577 EESP---MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 334 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE--MEEEEEEEEGEAGEAGEAESEK 391
P E + PP + +P S SP EE EE EA
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP-- 691
Query: 392 GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 451
PPE +P + + +S+P + L ++ + + +
Sbjct: 692 ------PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLS 744
Query: 452 PAVPEVENQP-PAGSNPGPESEGSGVPPRPEE 482
P E P P + P++E + P+PEE
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
Score = 66.2 bits (160), Expect = 2e-10
Identities = 95/356 (26%), Positives = 137/356 (38%), Gaps = 38/356 (10%)
Query: 71 VAPAPVL--MNQPPQIAPKRERKTIRIRDPNQGGKDIT---EEIMSGARTASTPTPPQTG 125
++P PV+ ++ PP+ +P P ++ E+ + +P P
Sbjct: 653 LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
Query: 126 GGLEPQANGETPQVAVIVRPD--DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSP 183
L E+P + + P RS+G ++ RP P P E S + P SP
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772
Query: 184 VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP------ISRETGEPYRLSPEPTPLAEPI 237
E EP L ++P + + Q +P +S +T EP+ LSP P EP
Sbjct: 773 QPE---EPCLC--AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH-LSPVPE---EPC 823
Query: 238 LEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES---SPE-- 292
L + S P+SE P +P P SH E + P + PE +PE
Sbjct: 824 LSPQPEESHLSPQSE---EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEEL 880
Query: 293 -LAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 351
L PPP PS SP+ P +P P + LSP EP + + PP +
Sbjct: 881 PLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS 940
Query: 352 SATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPAN 407
A AP A SP E E G G++ + ES L P S P AN
Sbjct: 941 PIITAAAPPALSPLGELEY------PFGAKGDS-DPESPLAAPILETPISPPPEAN 989
Score = 57.8 bits (138), Expect = 8e-08
Identities = 128/512 (25%), Positives = 170/512 (33%), Gaps = 124/512 (24%)
Query: 34 PVQPGAPGFYP-GASPTEF----GTYAGAYYPAQGVQQFPTGVAPAP-----VLMNQPPQ 83
P QPGA G P A+PT F T AG A G + P G P P + + PPQ
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 84 IAPKRERKTIRIRDP-NQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVI 142
+ + + +DP E A P P TG +P P +
Sbjct: 2167 VPAQ-----VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP------PMLGAS 2215
Query: 143 VRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS-PVLEPGSEPNLAVLSIPGD 201
RP G PG P QPS+P P P P L+ NLAV PG
Sbjct: 2216 SRPGAGQPGEFHTTPPGTP-------RHQPSTPDPFLKPRCPSLD-----NLAVPESPGV 2263
Query: 202 TMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV---EVTLSKP---VPESEFSS 255
+ EP LSP P + LEV E+ S P P F
Sbjct: 2264 G--------------GGKASEPL-LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVD 2308
Query: 256 SP----------LQAP-------TPLASHTVEIHEPN-GMVPSED-----LEPEVESSPE 292
SP L+ P TP AS VE P G+ P E L P S P+
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQ-VEPQSPGLGLRPQEPPPAQALAPSPPSHPD 2367
Query: 293 L----------APPPACPSESPVP------IAPTAQPEELLNGAPSPP---AVDLSPVSE 333
+ A PP P P P + P + P + + P+ P + SP++
Sbjct: 2368 IFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP 2427
Query: 334 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQE------EEMEEEEEEEEGEAGEAGEA 387
A+ S P S P + P + +++ + + E +AG
Sbjct: 2428 RPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHT 2487
Query: 388 ESEKGGEELLPPES------TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG 441
GG P +P+ N + T V P R +AVG
Sbjct: 2488 SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR----FTFPQAVG 2543
Query: 442 DLLDAFKEANPAVPEVENQPPAGSN----PGP 469
+ P VP+ PP G N PGP
Sbjct: 2544 E-----PSLKPPVPQPGLPPPHGINSHFGPGP 2570
Score = 52.0 bits (123), Expect = 4e-06
Identities = 72/336 (21%), Positives = 115/336 (34%), Gaps = 49/336 (14%)
Query: 45 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPV-----LMNQPPQIAPKRERKTIRIRDPN 99
G +P T G P+ V P P L QPP P ++++ + +
Sbjct: 4052 GTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTA 4111
Query: 100 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 159
GG ++ SG+ + ++ P P V++ +P +Q + +P
Sbjct: 4112 GGGSH--GQLGSGSSSEASSVPHLLA----------QPSVSLGDQPGSMTQNLLGPQQPM 4159
Query: 160 LPGPEHSPSESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISR 218
L P + + QP P P PVL+ G P + ++ G +Q + ++ +
Sbjct: 4160 LERPMQNNTGPQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR- 4212
Query: 219 ETGEPYRLSPEPTPLAEPIL-------EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 271
LSP+ + +L V + P E +SPLQ
Sbjct: 4213 ------HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266
Query: 272 HEP-NGMVPSEDLEPEVESSPELAPPPACPSESPV--PIAPTAQPEELLNGAPSPPAVDL 328
P G + P + P L PP S PV P+ PT PS P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP--------PPSSPQEPK 4318
Query: 329 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 364
P P ++ T + PPT P P+ P
Sbjct: 4319 RPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
Score = 43.5 bits (101), Expect = 0.002
Identities = 96/417 (23%), Positives = 141/417 (33%), Gaps = 71/417 (17%)
Query: 36 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAP----VLMNQPPQIAPKRERK 91
+PG P P P E + + P+ Q P P P + PP ++P E
Sbjct: 902 EPGEPPLSP--LPEEL-PLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE-- 956
Query: 92 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVA--VIVRPDDRS 149
+ P D E A TP P P+AN P+ +I+ P S
Sbjct: 957 ---LEYPFGAKGDSDPESPLAAPILETPISPP------PEANCTDPEPVPPMILPPSPGS 1007
Query: 150 -----QGAIIADRPGLPGP--EHS--PSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPG 200
++ P P +HS P S PS SP P V P S P V+ +
Sbjct: 1008 PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS-PIGKVVGV-S 1065
Query: 201 DTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQA 260
D +M E+ + EP SP P+P+ + + P P + S +
Sbjct: 1066 DEAELHEMETEKVSEPECPALEPSATSPLPSPMGD----LSCPAPSPAPALDDFSGLGED 1121
Query: 261 PTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA--------- 311
PL +P L E++ SP L P +P+ + P
Sbjct: 1122 TAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181
Query: 312 ---QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM----APPTIPSATPATAPSAT-- 362
Q E AP+PP + S + + AS + P + S P S +
Sbjct: 1182 CEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSME 1241
Query: 363 -------SPAQEE-----------EMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 401
SPA++E E ++ + G A G+AE EKG P S
Sbjct: 1242 LGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARS 1298
Score = 40.8 bits (94), Expect = 0.010
Identities = 90/382 (23%), Positives = 127/382 (33%), Gaps = 77/382 (20%)
Query: 60 PAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTP 119
P Q+ GV P+ L P A R+ + +RD T E+ S A+ P
Sbjct: 4631 PPSVQQKMVNGVTPSEELGEHPKDAASARDSERA-LRD--------TSEVKSLDLLAALP 4681
Query: 120 TPPQTGGG---LEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 176
TPP +E + ++P V P + + + P P E + + S
Sbjct: 4682 TPPHNQTEDVRMESDEDSDSPDSIV---PASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738
Query: 177 PT----PSPSPVLEPGSEPNLAV-LSIPGDTMTTIQ---MSVEESTPISRETGEPYRLSP 228
P P S + P ++P A+ L +PG T E S ++ L+
Sbjct: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNG 4798
Query: 229 EPTPLAEPILEVEVTLSKPVPESE---FSSSPLQAPTPLASHTVE--------------I 271
+AE LS +P S F SP +A T E
Sbjct: 4799 VMVAVAE-------LLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPD 4851
Query: 272 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ------------------P 313
P+ + + + P +L ESP P PT P
Sbjct: 4852 TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPP 4911
Query: 314 EELLNGAPSPPAVDL--SPVSEPEEQAKEV-TASMAPPTIPSATPATAPSATSPAQEEEM 370
EE PSPP L SP S P E E+ T +A P +PS P A+SP
Sbjct: 4912 EE-----PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP----LASSPESARPK 4962
Query: 371 EEEEEEEEGEAGEAGEAESEKG 392
EEGE + KG
Sbjct: 4963 PRARPPEEGEDSRPPRLKKWKG 4984
Score = 37.7 bits (86), Expect = 0.085
Identities = 95/415 (22%), Positives = 137/415 (33%), Gaps = 86/415 (20%)
Query: 111 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD-DRSQGAIIADRPGLPGPEHSPSE 169
SG T STPT P T G + +G + + R + D G + P L + P+
Sbjct: 1976 SGGTTPSTPTTPTTEG----EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031
Query: 170 SQ--PSSPS------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST- 214
Q P S P +P L+ + A Q++ +
Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG 2091
Query: 215 PISRETGEP---YRLSPEPTPLAEPILEVEVTL------------------------SKP 247
I+R+T P R+ P+P L P T+ S P
Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVP 2151
Query: 248 VPESE---FSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP 304
P+S F P Q P + S +P G+ P+ LEP ++P PP P+ +P
Sbjct: 2152 GPDSPGELFLKLPPQVPAQVPSQ-----DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206
Query: 305 VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 364
AQP L GA S P +P E T P TP PS P
Sbjct: 2207 ------AQPPML--GASSRPG-----AGQPGEF----------HTTPPGTPRHQPSTPDP 2243
Query: 365 AQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSV 424
+ + E+ G K E LL +P P S+ ++ S
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVG---GGKASEPLL----SPPPFGESRKALEVKKEELGASS 2296
Query: 425 PKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPR 479
P + G L + P V + P A S P+S G G+ P+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQ 2350
Score = 35.8 bits (81), Expect = 0.32
Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 57/215 (26%)
Query: 159 GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 218
G PGP+ P + + P P P PG+ VL
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--------------------- 4303
Query: 219 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 278
P +P P+ EP P Q P+P + E P
Sbjct: 4304 ----PVHPTPPPSSPQEP------------------KRPSQLPSPSSQLPTEAQLP---- 4337
Query: 279 PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 338
P+ P+ + P L PPP S + +A T + L P P +L+ +PE+
Sbjct: 4338 PTHPGTPKPQ-GPTLEPPPGRVSPAAAQLADTLFSKGL---GPWDPPDNLAETQKPEQ-- 4391
Query: 339 KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEE 373
+S+ P + P A+ + ++E EE
Sbjct: 4392 ----SSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422
Score = 34.7 bits (78), Expect = 0.72
Identities = 126/567 (22%), Positives = 194/567 (34%), Gaps = 113/567 (19%)
Query: 20 GQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQF-PTGVAPAPVLM 78
G G + + Y V G F+P SP G +G+ + G+ P V P P
Sbjct: 2567 GPGPTLGKPQSTNYTVATG--NFHPSGSP--LGPSSGSTGESYGLSPLRPPSVLPPPAPD 2622
Query: 79 NQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGG------LEPQA 132
P ++ +++ I P + +D + S TA P G LE Q
Sbjct: 2623 GSLPYLSHGASQRS-GITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 133 NGETPQVAVI----VRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS------------ 176
+ + +I R R + A G GP S ++PSSP+
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWG-AEPSSPAFEQLSRGQTPFA 2740
Query: 177 ------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 224
P+ P+L PGS P+ LS P T M V S + + Y
Sbjct: 2741 GTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDV-NSRQLVGGSQAFY 2799
Query: 225 RLSPEPTPL--------------AEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTV 269
+ +P P L A + +S P + QA +PLA +
Sbjct: 2800 QRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIST 2859
Query: 270 EIHEPNGMV-----PSEDLEPEVESSPELAP---------PPACP-----SESPVPIAPT 310
+ P V P++ +E L P PP P SE P +AP
Sbjct: 2860 RLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPE 2919
Query: 311 AQPEELLNGAP-----SPPAVDLSPVSEPEEQAKEVTASMAPPTI---PSAT------PA 356
++G P +PPA +L+ P K T + PS+T P
Sbjct: 2920 GLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPL 2979
Query: 357 TAPSATSPAQEEEMEEE-------EEEEE----GEAGEAGEAESEKGGEELLPPESTPIP 405
+ P ++ E++++ E++EE G + + + E G E L +
Sbjct: 2980 ALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLD 3039
Query: 406 ANLS-QNLEAAAATQVAVSVPKRR-------RKIKELNKKEAVGDLLDAFKEANPAVPEV 457
L+ + A T + ++ R ++ N+K LL E P PE
Sbjct: 3040 DLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGV-EPGPLGPE- 3097
Query: 458 ENQPPA--GSNPGPESEGSGVPPRPEE 482
E PPA S P S V P+ EE
Sbjct: 3098 ERPPPAADASEPRLASVLPEVKPKVEE 3124
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 72.0 bits (175), Expect = 4e-12
Identities = 60/257 (23%), Positives = 92/257 (35%), Gaps = 17/257 (6%)
Query: 117 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 176
+TP+PP T P +P ++ P + + P P SP + ++P
Sbjct: 1436 TTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495
Query: 177 PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP---TPL 233
PT +PSP P ++ P T TT+ + S P + T P +P P TP+
Sbjct: 1496 PTTTPSP-------PTTTPITPPAST-TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547
Query: 234 AEPILEVEV---TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 290
P + T P P + + P P+P + T P P ++
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607
Query: 291 PELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 347
PPP P PI P L PSPP + + T + +P
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667
Query: 348 PTIPSATPATAPSATSP 364
P + TP + +SP
Sbjct: 1668 PITTTTTPPPTTTPSSP 1684
Score = 71.6 bits (174), Expect = 5e-12
Identities = 74/299 (24%), Positives = 98/299 (32%), Gaps = 32/299 (10%)
Query: 68 PTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQG-GKDITEEIMSGARTAS-----TPTP 121
PT P PP P T P T I A T + TP+P
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525
Query: 122 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 181
P T P +P + P + P SP + ++P PT +P
Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP-------SPPPTTTTTPPPTTTP 1578
Query: 182 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVE 241
SP P S P T TT + S P + T P +P P P PI
Sbjct: 1579 SP-------PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITPPT 1630
Query: 242 VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPS 301
T + P P + S P TP + T P P + PPP
Sbjct: 1631 STTTLP-PTTTPSPPPTTTTTPPPTTTPS--------PPTTTTPSPPITTTTTPPPTTTP 1681
Query: 302 ESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
SP+ P+ P PSP SP++ + T S P T+ + +P T PS
Sbjct: 1682 SSPITTTPS--PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/260 (25%), Positives = 87/260 (33%), Gaps = 19/260 (7%)
Query: 153 IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 212
I P P P+ + P+ TPSP P + P S P T TT +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454
Query: 213 STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH 272
S PIS T P +P P P + P P + +++P TP T I
Sbjct: 1455 SPPISTTTTPPPTTTPSP-----PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 273 EPNGMVPSEDLEPEVESSP----ELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPA 325
P + L P SP PPP P PI P L PSPP
Sbjct: 1510 PP---ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566
Query: 326 VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 385
+ + T + +PPTI + TP P T+P+ +
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTP---PPTTTPSPPTTTTTTPPPTTTPSPPTT 1623
Query: 386 EAESEKGGEELLPPESTPIP 405
+ LPP +TP P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSP 1643
Score = 55.1 bits (131), Expect = 5e-07
Identities = 52/218 (23%), Positives = 75/218 (34%), Gaps = 20/218 (9%)
Query: 117 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 176
+TP+PP T P +P P I P SP + ++P
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT------ITTTTPPPTTTPSPPTTTTTTPP 1613
Query: 177 PTPSPSP-----VLEPGSE---PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 228
PT +PSP + P S P S P T TT + S P + P +
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 229 EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 288
P P P + T P P + ++P TP + T + PS
Sbjct: 1674 TPPPTTTPSSPITTT---PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730
Query: 289 SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 326
SP P P + + +P T+ P L P PP++
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTSSP---LTTTPLPPSI 1765
Score = 53.1 bits (126), Expect = 2e-06
Identities = 82/337 (24%), Positives = 112/337 (33%), Gaps = 49/337 (14%)
Query: 47 SPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMN-QPPQIAPKRERKTIRIRDPNQGGKDI 105
+PT GT P T V P P Q P P T+ P G
Sbjct: 4003 TPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQT 4057
Query: 106 TEEIMSGARTASTPTPPQTGGGLEPQANGETP-QVAVIVRPDDRSQGA-------IIADR 157
T TPTP TG Q TP V P G I
Sbjct: 4058 PTTTPITTTTTVTPTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4113
Query: 158 PGLPGPEHSPSESQPSSP-------SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV 210
P P + +++ ++P +PTP+P+ P + P ++ T T
Sbjct: 4114 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQT 4172
Query: 211 EESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVE 270
+TPI+ T ++P PTP T + P+ E S+ P ++ TP S +
Sbjct: 4173 PTTTPITTTT----TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS 4228
Query: 271 IHEPNGMVPSEDLEPEVESSPELAP-PPACPSESPVPIAPTAQPEELLNG--APSPPAVD 327
P ES+ L+ PPA S P + P G PP+
Sbjct: 4229 -------------SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 4275
Query: 328 LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 364
SP P T S + PT PS T SA +P
Sbjct: 4276 TSPPGTPTRGT--TTGSSSAPT-PSTVQTTTTSAWTP 4309
Score = 52.4 bits (124), Expect = 3e-06
Identities = 73/307 (23%), Positives = 93/307 (30%), Gaps = 36/307 (11%)
Query: 24 STYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP--TGVAPAPVLMNQP 81
ST +P P P P + T P P T +P P P
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572
Query: 82 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV 141
P T P T +T TPP T P TP +
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1632
Query: 142 IVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGD 201
P P SP + ++P PT +PSP P S P
Sbjct: 1633 TTLP---------------PTTTPSPPPTTTTTPPPTTTPSP-------PTTTTPSPPIT 1670
Query: 202 TMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP 261
T TT + S+PI+ P P+P P + T + P S + SP
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT---PSSTTTPSPPPTT 1727
Query: 262 TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP 321
S T P + + L P SSP L P PS +P PT P P
Sbjct: 1728 MTTPSPTTTPSPPTTTMTT--LPPTTTSSP-LTTTPLPPSITP----PTFSP--FSTTTP 1778
Query: 322 SPPAVDL 328
+ P V L
Sbjct: 1779 TTPCVPL 1785
Score = 37.0 bits (84), Expect = 0.14
Identities = 77/349 (22%), Positives = 111/349 (31%), Gaps = 60/349 (17%)
Query: 47 SPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMN-QPPQIAPKRERKTIRIRDPNQGGKDI 105
+PT GT P T V P P Q P P T+ P G
Sbjct: 4118 TPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQT 4172
Query: 106 TEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEH 165
T TPTP TG P + T +A + + P PE
Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN--------------PPPES 4218
Query: 166 SPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYR 225
S ++ S+ SP + +L P MT+ + P + G +
Sbjct: 4219 STPQTSRSTSSPLTESTTLLSTLP---------PAIEMTSTAPPSTPTAPTTTSGG--HT 4267
Query: 226 LSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEP 285
LSP P+ P P + SS P+ + + T P P+ P
Sbjct: 4268 LSPPPSTTTSPP-------GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT---PTPLSTP 4317
Query: 286 EVESSPELAPPPA----CPSESPVPIAPTAQPEELLNGAPSPPAV----DLSPVSE---- 333
+ + L P P+ C + AP EE+ NG LS E
Sbjct: 4318 SIIRTTGLRPYPSSVLICCVLNDTYYAPG---EEVYNGTYGDTCYFVNCSLSCTLEFYNW 4374
Query: 334 --PEEQAKEVTASMAPPTI--PSATPATAPSATSPAQEEEMEEEEEEEE 378
P + T S + PT PS+TP+ T P + + + +E E
Sbjct: 4375 SCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENE 4423
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 72.0 bits (175), Expect = 4e-12
Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%)
Query: 136 TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 195
+P ++ + P ++ A+ P L P SP S P SP TPSP A
Sbjct: 383 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 439
Query: 196 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 255
S P S S P+S P S P LA P L+V + P S ++
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 256 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 309
P QAP PLA+ +++ +P P P +++ P +PP + P ++P +P++P
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 554
Query: 310 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 350
A P LL PSPPA +P + +T ++A PP
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614
Query: 351 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 406
PS +P++ S A EE G +GG PP + PA
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 669
Query: 407 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 464
S+ A + A P + + + + + A PA ++ P G
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729
Query: 465 SNPGPESEGSG 475
++ G + G+G
Sbjct: 730 TSGGKAAAGAG 740
Score = 57.4 bits (137), Expect = 1e-07
Identities = 81/336 (24%), Positives = 121/336 (36%), Gaps = 75/336 (22%)
Query: 47 SPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP----PQIAPKRERKTIRIRDPNQGG 102
+P AGA G PT P+P + + ++ R + R R P +G
Sbjct: 150 APKRSALSAGARRDTSG----PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
Query: 103 KDITEEIMSGARTASTPTP---PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 159
+ + T +P P GGGL+ RP RS +
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQ--------------RPASRSLSSSAT---- 247
Query: 160 LPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRE 219
P SP+ S PS+ +P+ +P + L L P + TP ++
Sbjct: 248 ---PLSSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPP------------QVTPPRKD 291
Query: 220 TGE---PYRLSPEPTPLAEPILEVEVTLSKPV-PESEFSSSPLQAPTPLASHTVEIHEPN 275
P SP TP L+ + + P P S + L P PLA
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP--------- 342
Query: 276 GMVPSEDLEPEVESSPELAPPPACPSESPVPI-APTAQPEELLNGAPSPPAVDLSPVSEP 334
PS P +++ P +PP PS++ + +PT Q PSPP LSP++ P
Sbjct: 343 ---PSPSAPPSLQTLP--SPPATPPSQATTSLGSPTLQATHSF--LPSPP---LSPLATP 392
Query: 335 EEQAKE------VTASMAPPTIPSATPATAPSATSP 364
QA + A +PP P +P PS +P
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Score = 50.8 bits (120), Expect = 1e-05
Identities = 97/423 (22%), Positives = 141/423 (33%), Gaps = 55/423 (13%)
Query: 37 PGAPGFYPGASPTEFGT----YAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKT 92
P P P + T G+ ++ P+ + T AP + PP AP +
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
Query: 93 ---IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRS 149
+ P+ + + A + P+PP P + +P V+ P ++
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA----PFSPPASPPVSPSATPPSQA 470
Query: 150 QGAIIADRPGLPGPEHSPSESQPSSPSPTP---SPSP-------VLEPGSEPNLAVLSIP 199
++ A P L P SP S P SPS TP +P P + +P + A+ + P
Sbjct: 471 PPSLAA--PPLQVPP-SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527
Query: 200 GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQ 259
+ + S P S P P P A P+L + VP S +S LQ
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQ 584
Query: 260 AP--TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE 314
AP P + P + P P S L+ P S + T+ PE
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPE 640
Query: 315 ELLNGAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQ 366
E L G S P SP + E A A P P A P P AT P
Sbjct: 641 E-LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 699
Query: 367 EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPK 426
+ + E E E+ + G P P A A + PK
Sbjct: 700 ADGLCTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPK 749
Query: 427 RRR 429
+ R
Sbjct: 750 QAR 752
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 72.0 bits (175), Expect = 4e-12
Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%)
Query: 136 TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 195
+P ++ + P ++ A+ P L P SP S P SP TPSP A
Sbjct: 344 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 196 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 255
S P S S P+S P S P LA P L+V + P S ++
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 256 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 309
P QAP PLA+ +++ +P P P +++ P +PP + P ++P +P++P
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 515
Query: 310 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 350
A P LL PSPPA +P + +T ++A PP
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575
Query: 351 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 406
PS +P++ S A EE G +GG PP + PA
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 630
Query: 407 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 464
S+ A + A P + + + + + A PA ++ P G
Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690
Query: 465 SNPGPESEGSG 475
++ G + G+G
Sbjct: 691 TSGGKAAAGAG 701
Score = 56.2 bits (134), Expect = 2e-07
Identities = 106/466 (22%), Positives = 154/466 (33%), Gaps = 65/466 (13%)
Query: 4 PSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFY------PGASPTEFGTYAGA 57
P Q++ P A + S P+ P P AP P P++ T G+
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332
Query: 58 --------YYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKT---IRIRDPNQGGKDIT 106
+ P+ + T AP + PP AP + + P+ +
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Query: 107 EEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS 166
+ A + P+PP P + +P V+ P ++ ++ A P L P S
Sbjct: 393 AVHLLQAPFSPPPSPPVQA----PFSPPASPPVSPSATPPSQAPPSLAA--PPLQVPP-S 445
Query: 167 PSESQPSSPSPTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPI 216
P S P SPS TP +P P + +P + A+ + P + + S P
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 217 SRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEP 274
S P P P A P+L + VP S +S LQAP P + P
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 275 N---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLS 329
+ P P S L+ P S + T+ PEE L G S P S
Sbjct: 563 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAAS 617
Query: 330 PVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGE 383
P + E A A P P A P P AT P + + E E E+
Sbjct: 618 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 677
Query: 384 AGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 429
+ G P P A A + PK+ R
Sbjct: 678 PAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 713
Score = 55.1 bits (131), Expect = 5e-07
Identities = 88/360 (24%), Positives = 122/360 (33%), Gaps = 54/360 (15%)
Query: 38 GAPGFYPGASPTEFGTYAGAYYPAQGVQQFPT----------GVAPAPVLMNQP-PQIAP 86
GA G P A G GA P + PT G P P P +P
Sbjct: 51 GAVGRKPLAERA--GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108
Query: 87 KRERKTIRIRDPNQGGKDIT-EEIMSGARTASTPTPPQTGGGLEPQANGETPQV-AVIVR 144
R T R Q G I+ EE ++ + P G +G TP + +
Sbjct: 109 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 168
Query: 145 PDDRSQGAIIA---------DRPGLPGPEHS---PSESQPSSPSPTPSPSPVLEPGSE-P 191
R+ G + RP GP S SE + PSP P G + P
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228
Query: 192 NLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPES 251
LS +++ S + R P + P+ P
Sbjct: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288
Query: 252 EFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI-APT 310
SSSPL P+P A PS P +++ P +PP PS++ + +PT
Sbjct: 289 PLSSSPLATPSPSAP------------PSPSAPPSLQTLP--SPPATPPSQATTSLGSPT 334
Query: 311 AQPEELLNGAPSPPAVDLSPVSEPEEQAKE------VTASMAPPTIPSATPATAPSATSP 364
Q PSPP LSP++ P QA + A +PP P +P PS +P
Sbjct: 335 LQATHSF--LPSPP---LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389
Score = 40.8 bits (94), Expect = 0.010
Identities = 63/264 (23%), Positives = 93/264 (35%), Gaps = 53/264 (20%)
Query: 151 GAIIADRPGLPGPEHSP-----SESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDT-MT 204
GA I + GP + + + P+ SP PV PG + PG
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT---TRPGPLGQK 123
Query: 205 TIQMSVEESTPISRETGEPYRLSPE---------PTP-LAEPILE-------VEVTLSKP 247
+++S EE+ + T P R + PTP P + EV L +P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 248 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEV--------------ESSPEL 293
P + P + P S E H P+ P ++P
Sbjct: 184 APSAR-PRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241
Query: 294 APPPACPSESPVPIAPT--AQP-----EELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 346
+P + PS P AP +QP + L +PP D +P P + T S +
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 347 PPTIPSATPA----TAPSATSPAQ 366
P PSA P+ +P AT P+Q
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQ 325
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 70.9 bits (172), Expect = 9e-12
Identities = 109/487 (22%), Positives = 187/487 (38%), Gaps = 34/487 (6%)
Query: 322 SPPAVDL-SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 380
SPPA + SP E + KE S A P A +P+ ++ + +EE +
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562
Query: 381 AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAV 440
++ E E K E+ PE PA E A + A S K + +KE K A
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAK-----EEAKSPAEAKSPEKAKSPVKEEAKSPA- 616
Query: 441 GDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENI 500
+ KE + EV++ A S E++ PE+ + K AE
Sbjct: 617 -EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675
Query: 501 QPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKT 560
P + K K++ P E+ K +E + + +++ P + + + KT
Sbjct: 676 SPEKAKSPVKAEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 561 PLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQG 620
P + P + + + +P A TL + P P E R PA P +++
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAK----TLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 621 PRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 677
++E P K A + ED K + E K K ++++ +E K ++ ++
Sbjct: 789 VKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE----VKVKEPPKKA 842
Query: 678 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 737
TP+ ++ K + +E K ++ E A+ +P S A
Sbjct: 843 EEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 738 LKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD-------EVFEKKQKEMDEAATAEE 789
KVPT EK V ++ + + E K + DD + EKK+ ++ T EE
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 790 RGRLKEE 796
+ + EE
Sbjct: 961 KAKKPEE 967
Score = 70.1 bits (170), Expect = 2e-11
Identities = 100/461 (21%), Positives = 171/461 (37%), Gaps = 45/461 (9%)
Query: 72 APAPVLMNQPPQI-APKRE--RKTIRIRDPNQGGKDITEEIMSGARTAS---TPTPPQTG 125
+PA PP+ +P++E + ++ P + EE S A S +P +
Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEE 611
Query: 126 GGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL 185
+A + A + A + PE + S + + SP + SPV
Sbjct: 612 AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671
Query: 186 EPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL-------SPEPTPLAEPIL 238
P A + + + + +P+ E P + + P P+
Sbjct: 672 AEAKSPEKAKSPVKAEAKSP----EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 239 EVEVTLSKPV-PESEFSSSPLQAPTPLASHTVEIHEPNGMVPS-EDLEPEVESSPELAPP 296
E T K P E + SP +A +P + T+++ P P+ E+ + PE A
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 297 PA-----CPSESPVPIAPTAQ-PEELL---NGAPSPPAVDLSP----VSEPEEQAKEVTA 343
P P ++ P+ A+ PE+ + SP + P V EP ++A+E A
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 344 SMAPPTIPSATP----ATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPP 399
P T A A P EE+ E E+ + EA + E+E + P
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 400 ESTPIPANLSQNLEAAAATQVAVSVP---KRRRKIKELNKKEAVGDLLDAFKEANPAVPE 456
+ P + ++ + T+VA P K + K KKEA + D KE PE
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT-KEEKAKKPE 966
Query: 457 VENQPPAGSNPGPESEGSGVPPRPE----EADETWDSKEDK 493
+ + A + ++ S P +P+ E + D K+ K
Sbjct: 967 EKPKTEAKAKEDDKTL-SKEPSKPKAEKAEKSSSTDQKDSK 1006
Score = 69.7 bits (169), Expect = 2e-11
Identities = 109/490 (22%), Positives = 188/490 (38%), Gaps = 47/490 (9%)
Query: 62 QGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA-RTASTPT 120
+G+ + P+ V + ++ K E++T+ + + + + +TEE+ + A
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQ-VTEEVTEEEEKEAKEEE 482
Query: 121 PPQTGGGLEPQANG-----ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSP 175
+ GG E +A G ++P P+ ++ + + P SP + + SP
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS-PAEAKSPEKEEAKSP 541
Query: 176 SPTPSP----SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE--STPISRETGEPYRL-SP 228
+ SP SP E P A + + ++ E +P E P SP
Sbjct: 542 AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP 601
Query: 229 E--PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 286
E +P+ E E + P E + SP + +P + + E ++ E E
Sbjct: 602 EKAKSPVKE---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 287 VESSPELAPPPA-----CPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP-EEQAKE 340
SPE A P P ++ P+ A+ E A P +E+AK
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Query: 341 VTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG----EAGEAESEKGGEEL 396
+ +P + TP A SP +EE E+ + +A ++ EA++ E
Sbjct: 719 PEKAKSPVKEEAKTP---EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 397 LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAV 454
P + P A S E + + A S K K KE+ KKE V +P
Sbjct: 776 SPADKFPEKAK-SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV---------KSPVK 825
Query: 455 PEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPG-EQKYEYKSDQ 513
E + Q P ++E P P + +E DSK+++ E +P E+K E ++
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATP-KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 514 WKPLNLEEKK 523
K +E KK
Sbjct: 885 PKESKVEAKK 894
Score = 54.3 bits (129), Expect = 9e-07
Identities = 85/367 (23%), Positives = 134/367 (36%), Gaps = 28/367 (7%)
Query: 170 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 229
S P PS S ++ SE + V+ ++ EE+ T E + + E
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 230 PTPLAEPILEVEVTL-----SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 284
E E E +K P E +S +A +P+ E E
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP-SPPAVDLSPVSEPEE---QAKE 340
P SPE A PA P A + + EE + A P SP E + +AK
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600
Query: 341 VTASMAPPTIPSATPATAPS-----ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEE 395
+ +P + +PA A S A SPA+ + E+ + + EA +A+S + EE
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEE 659
Query: 396 LLPPESTPIPANLSQNLEAAAATQV---AVSVPKRRRKIKELNK-----KEAVGDLLDAF 447
PE P A + V A S K + +KE K K V + +
Sbjct: 660 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSP 719
Query: 448 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKY 507
++A V E P +P E S PE+A +K + + E P +++
Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKS-----PEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 508 EYKSDQW 514
+D++
Sbjct: 775 RSPADKF 781
Score = 53.5 bits (127), Expect = 1e-06
Identities = 132/625 (21%), Positives = 214/625 (34%), Gaps = 90/625 (14%)
Query: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
P P P P + +S T I++ EE + ++ + + E T + EV
Sbjct: 417 PIPFSLPEGLPKIPSVS------THIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV 470
Query: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDL-EPEVESSPELAPPPAC 299
K E E E P P+E+ PE E+ +
Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP----PAEEAASPEKEAKSPVKEEAKS 526
Query: 300 PSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATA 358
P+E+ P A+ P E+ + + S PE ++ E + +P + S A +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586
Query: 359 PS---ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAA 415
P+ A SPA+ + E+ + + EA EA+S E P E S E A
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Query: 416 AATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSG 475
+ + A S K K E K +A PE P PE S
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPV---------KAEAKSPEKAKSPVKAEAKSPEKAKS- 696
Query: 476 VPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQF 535
P EEA +K A++ P + K K + P EK +
Sbjct: 697 --PVKEEAKSPEKAKSPVKEEAKS--PEKAKSPVKEEAKTP----EKAK----------- 737
Query: 536 IFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRG 595
S K E K+P + P + + TL +
Sbjct: 738 ---SPVKEEA-------------KSPEKAKSPEKAK------------------TLDVKS 763
Query: 596 PPRGGPGGELPRGPAGLGPRRSQQGPRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSK 652
P P E R PA P +++ ++E P K A + ED K + E K K
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVK 821
Query: 653 RTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVID 712
++++ +E K ++ ++ TP+ ++ K + +E K ++
Sbjct: 822 SPVKEEEKPQE----VKVKEPPKKAEEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVE 875
Query: 713 LIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD 771
E A+ +P S A KVPT EK V ++ + + E K + DD
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935
Query: 772 EVFEKKQKEMDEAATAEERGRLKEE 796
++ K ++ A E+ KEE
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEE 960
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 69.7 bits (169), Expect = 2e-11
Identities = 122/543 (22%), Positives = 178/543 (32%), Gaps = 115/543 (21%)
Query: 27 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQF--PTGVAPAPVLMNQPPQI 84
VVP ++ PV P P PT+ A P + V + P +P P + P ++
Sbjct: 10532 VVPEKKVPVPPPKK---PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV 10588
Query: 85 APKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV--- 141
P+++ + P + E P PP + P E P+VAV
Sbjct: 10589 VPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEK 10648
Query: 142 ----IVRPDDRSQGAIIADRPGLPGPEHSPSE----SQPSSP--------SPTPSPSPVL 185
+ P S + + P E P+E +P++P P P
Sbjct: 10649 KVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPA 10708
Query: 186 EPGSEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPILEVEVT 243
+P L + +P + E+ P + ++ P PE P +V V
Sbjct: 10709 VVAKKPELPPVKVPEVPKEVVP---EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 244 LSKPVPESEFSSSPL-----QAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPE------ 292
VP ++ P + P E P E++ PE E +PE
Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP 10825
Query: 293 -------LAPPPACPSES---------PVPIAPTA------QPEELL-------NGAPSP 323
PPPA P E PV P A +PE+++ P P
Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPP 10885
Query: 324 PAVDLSPVSEPEEQAKEVTASMAP--PTIP---SATPATAPSATS------PAQEEEMEE 372
PA V E Q K + P P +P TP P P ++ E +E
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945
Query: 373 E---------EEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVS 423
E EEE E + E K PP P+ + +E T
Sbjct: 10946 EVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPV-----EEVEVPTVT----- 10995
Query: 424 VPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEA 483
KR RKI E K E PA+P +P P PE+E + P P E
Sbjct: 10996 --KRERKIPEPTK----------VPEIKPAIPLPAPEP----KPKPEAEVKTIKPPPVEP 11039
Query: 484 DET 486
+ T
Sbjct: 11040 EPT 11042
Score = 64.7 bits (156), Expect = 6e-10
Identities = 100/429 (23%), Positives = 144/429 (33%), Gaps = 62/429 (14%)
Query: 81 PPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVA 140
P ++ P+++ + P + E P PP + P E P+ A
Sbjct: 10501 PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAA 10560
Query: 141 V-------IVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSP---------- 183
V + P S + + P PE + P P TP P
Sbjct: 10561 VPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK 10620
Query: 184 --VLEPGSEPNLAVLSIPGDTMTTI-QMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
+ P +P + +P + + V E+ P P SP P EP
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-------PKPESPPPEVFEEP---E 10670
Query: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
EV L +P E ++ P P A V + P VP + V PEL PP
Sbjct: 10671 EVALEEPPAE------VVEEPEPAAPPQVTV-PPKKPVPEKKAPAVVAKKPEL--PPVKV 10721
Query: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
E P + P + ++ P P + V P+E E +A P P PA P
Sbjct: 10722 PEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV--PKEVVPE--KKVAVPKKPEVPPAKVPE 10777
Query: 361 A-TSPAQEEE----MEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAA 415
P EE+ + E E E E E E EE+ P E P+P + E
Sbjct: 10778 VPKKPVLEEKPAVPVPERAESPPPEVYE--EPEEIAPEEEIAPEEEKPVPVAEEEEPEVP 10835
Query: 416 AATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSG 475
+VP+ +KI KK V +A P +V +P P P
Sbjct: 10836 PP-----AVPEEPKKIIP-EKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP----- 10884
Query: 476 VPPRPEEAD 484
PP P + D
Sbjct: 10885 -PPAPPKED 10892
Score = 60.8 bits (146), Expect = 9e-09
Identities = 87/325 (26%), Positives = 121/325 (37%), Gaps = 33/325 (10%)
Query: 167 PSESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTT-IQMSVEESTPISRETGEPY 224
P + P P P+P V P ++ P + IP + T + VE P P
Sbjct: 10036 PKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP-----KVPK 10090
Query: 225 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 284
+ P P P+A P E + + VPE E P + V E + E++
Sbjct: 10091 KREPVPVPVALPQEEEVLFEEEIVPEEEVL--PEEEEVLPEEEEVLPEEEEVLPEEEEIP 10148
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTAS 344
PE E P P E VP PEE + P +PV PE + K
Sbjct: 10149 PEEEEVP--------PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPV--PEIKKKVTEKK 10198
Query: 345 MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 404
+ P A PA P +E+ + +EEE E E E EE +P E I
Sbjct: 10199 VVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258
Query: 405 -------PANLSQNLEAA---AATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA- 453
P + + ++ A A T V V K+ + +E V + KEA PA
Sbjct: 10259 EEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQK-KEAPPAK 10317
Query: 454 VPEVENQPPAGSNPGPESEGSGVPP 478
VPEV + P P+ E VPP
Sbjct: 10318 VPEVPKKVPEKKVLVPKKE--AVPP 10340
Score = 56.2 bits (134), Expect = 2e-07
Identities = 100/420 (23%), Positives = 150/420 (35%), Gaps = 86/420 (20%)
Query: 129 EPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPG 188
E + + P+V + +++ AI P P + P +P P P V P
Sbjct: 9254 EEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPA 9313
Query: 189 SE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKP 247
+ P + +P EE P+ P+ P A P +V KP
Sbjct: 9314 PKVPEVPKKPVP-----------EEKKPVP---------VPKKEPAAPP--KVPEVPKKP 9351
Query: 248 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPS----ES 303
VPE + + + E+ + G+V E + + + E +PPPA P +
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQK--GVVTEEKIT--IVTQREESPPPAVPEIPKKKV 9407
Query: 304 PVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP--------------- 348
P P + EE + P PA+ PV E + A APP
Sbjct: 9408 PEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKR 9467
Query: 349 ---------TIPSATPAT-----APSATSPAQEEE-----MEEEEEEEEGEAGEAGEAES 389
+P T A S ++EEE + EEE EE E E E E
Sbjct: 9468 FVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEV 9527
Query: 390 EKGGEELLPPESTPIPANLSQNLEAAAA------TQVAVSVPKRRRKIKE---LNKKEAV 440
+ EE + E I +S+ +EA A + V PK KI+E EA
Sbjct: 9528 MEEPEEYVVEEKLHI---ISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAP 9584
Query: 441 GDLLDAFKEANPAVPEVENQPP-----AGSNPGPESEGSGVPPRPEEADETWDSKEDKIH 495
++ K P VP+ E PP P PE + VPP+ + +E +K + H
Sbjct: 9585 KKIVPEKKVPAP-VPKKEKVPPPKVPEEPKKPVPEKK---VPPKVIKMEEPLPAKVTERH 9640
Score = 55.8 bits (133), Expect = 3e-07
Identities = 85/357 (23%), Positives = 124/357 (34%), Gaps = 64/357 (17%)
Query: 72 APAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQ 131
+P P + +P +IAP+ E I + + EE P P EP+
Sbjct: 10798 SPPPEVYEEPEEIAPEEE-----IAPEEEKPVPVAEE--------EEPEVPPPAVPEEPK 10844
Query: 132 ANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEP 191
+V VI +P+ A P P PE + + P P P+P E E
Sbjct: 10845 KIIPEKKVPVIKKPE--------APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEK 10896
Query: 192 NLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPES 251
+ +IP ++ P + E L+P P E + + KP P+
Sbjct: 10897 IFQLKAIP-----------KKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945
Query: 252 EFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA 311
E + P E EP V + LE + + PPP E VP T
Sbjct: 10946 EVVLKSVLRKRP------EEEEPK--VEPKKLEKVKKPAVPEPPPPKPVEEVEVPTV-TK 10996
Query: 312 QPEELLNGAPSPPAVDLSPVSEPEEQAK---EVTASMAPPTIPSATPATAPSATSPAQEE 368
+ ++ P P+ PE + K EV PP P TP AP T P +
Sbjct: 10997 RERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAP-VTVPVVGK 11055
Query: 369 EMEEEEEEEEGEAGEAG------------EAESEK-----GGEELLPPESTPIPANL 408
+ E + +EE + EAE K GGE+ PP+ P L
Sbjct: 11056 KAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEK--PPDEAPFTYQL 11110
Score = 52.4 bits (124), Expect = 3e-06
Identities = 62/292 (21%), Positives = 108/292 (36%), Gaps = 35/292 (11%)
Query: 219 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLA-SHTVEIHEPNGM 277
E E + P+ ++E I+ + +K VP E + + P + V + E +
Sbjct: 10431 EVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRV 10490
Query: 278 VPSEDLEPEVESSPELAP------PPACPSESPVPIAPTAQPE---ELLNGAPSPPAVDL 328
P++ PEV E+ P PPA E+P P P A E E P P ++
Sbjct: 10491 PPTK--VPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEV 10548
Query: 329 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 388
P PE V P IP + P +E E++ + E +
Sbjct: 10549 PPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVK 10608
Query: 389 SEKGGEELLPPESTPIPANLSQNLEAAAATQV-AVSVPKRR-----------------RK 430
+ +E++P + P+P + +V V+VP+++ +
Sbjct: 10609 VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE 10668
Query: 431 IKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEE 482
+E+ +E ++++ E PA P PP P PE + V + E
Sbjct: 10669 PEEVALEEPPAEVVE---EPEPAAPPQVTVPP--KKPVPEKKAPAVVAKKPE 10715
Score = 50.8 bits (120), Expect = 1e-05
Identities = 79/331 (23%), Positives = 120/331 (36%), Gaps = 59/331 (17%)
Query: 236 PILEVEV--TLSKPVPESEFSSSPLQAPTPLASHTVEIHE----PNGMVP---SEDLEPE 286
P++ V+V KPVPE + P+ P + ++ E P VP + +P
Sbjct: 9944 PVIPVKVPEVPRKPVPEEK---KPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPP 10000
Query: 287 VESSPELAPPPACPSESPVPI-----APTAQPEELLNG--------APSPPAVDLSPVSE 333
PE+ P + PVP+ AP A+ E+ P+P V+ P
Sbjct: 10001 PAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKV 10060
Query: 334 PEEQAKEVTASMAPPTIPS---ATPATAPSATSPA-------QEEEMEEEEE-------- 375
PE K + P +P A P P P QEEE+ EEE
Sbjct: 10061 PEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVL 10120
Query: 376 -EEEGEAGEAGEAESEK----GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRK 430
EEE E E E+ EE +PPE +P E +P+ + K
Sbjct: 10121 PEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPK 10180
Query: 431 IKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 490
+ V ++ E +P+ E PPA PE VP + EE +
Sbjct: 10181 VP---VPAPVPEIKKKVTEKKVVIPKKEEAPPA---KVPE-----VPKKVEEKRIILPKE 10229
Query: 491 EDKIHNAENIQPGEQKYEYKSDQWKPLNLEE 521
E+ + +P E+ + +P ++EE
Sbjct: 10230 EEVLPVEVTEEPEEEPISEEEIPEEPPSIEE 10260
Score = 47.4 bits (111), Expect = 1e-04
Identities = 70/274 (25%), Positives = 105/274 (38%), Gaps = 45/274 (16%)
Query: 228 PEPTPLAEPILEVEVTL--SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEP 285
P TP+ E ++EV+V +K + SE ASHT E E + VP E
Sbjct: 9218 PSRTPVQEEVIEVKVPAVHTKKMVISEEKMF-------FASHTEE--EVSVTVPEVQKEI 9268
Query: 286 EVES------SPELAPPPACPS--ESPVP--IAPTAQPEELLNGAPSPPAVDLSPVSEPE 335
E S + PPP P E P P +AP P+++ AP P V PV PE
Sbjct: 9269 VTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPV--PE 9326
Query: 336 EQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEE 395
E+ P +P PA P ++ EE+ + EA A+ + +
Sbjct: 9327 EKK--------PVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKG 9378
Query: 396 LLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVP 455
++ E I ++ A VP+ R+ + K+E V P VP
Sbjct: 9379 VVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVP--RKEEEV--------PPPPKVP 9428
Query: 456 EVENQPPAGSN---PGPESEGSGVPPRPEEADET 486
+ +P P P ++ PPR E + +T
Sbjct: 9429 ALPKKPVPEEKVAVPVPVAK-KAPPPRAEVSKKT 9461
Score = 44.7 bits (104), Expect = 7e-04
Identities = 102/474 (21%), Positives = 158/474 (33%), Gaps = 127/474 (26%)
Query: 122 PQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP 181
P+ +E + P+ + P+ + A + + +P P+ +P P P
Sbjct: 9566 PKIPAKIEEPPPAKVPEAPKKIVPEKKVP-APVPKKEKVPPPK---VPEEPKKPVPEKKV 9621
Query: 182 SPVLEPGSEPNLAVLS-----IPGDTMTTIQMSVEESTPISRETGEPYRLSPE------- 229
P + EP A ++ I + + ++ +E+ P +R EP R PE
Sbjct: 9622 PPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLK 9681
Query: 230 PTPLAEPILEVEVTLSKPVPESEFS-SSPLQAPTPLASHTV------------------- 269
P EP +V + V E + S +P + P P+ T+
Sbjct: 9682 PKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQR 9741
Query: 270 ----EIHEPNGMVPSEDLEPEVE----------------------SSPELAPPPACPSES 303
E +E E+ EP E + PE P E
Sbjct: 9742 EEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEE 9801
Query: 304 PVPIAPTAQPEELLNGA---------------PSPPAVDLSP------------VSEPEE 336
PVP P A P ++L A P PP V P +E
Sbjct: 9802 PVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKE 9861
Query: 337 QAKEVTAS--------MAPPTIPSATPATAPSATSPAQEEEMEEEE-------------- 374
Q E A +A +P AP P +E+E EE
Sbjct: 9862 QVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEY 9921
Query: 375 --EEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR--- 429
EEEE E E +E+ ++P + +P + + V VPK++
Sbjct: 9922 LVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPR------KPVPEEKKPVPVPKKKEAPP 9975
Query: 430 -KIKELNKK--EAVGDLLDAFKEANPA-VPEVENQP-PAGSNPGPESEGSGVPP 478
K+ E+ KK E V L+ ++ PA VPEV +P P P P + PP
Sbjct: 9976 AKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPP 10029
Score = 37.0 bits (84), Expect = 0.14
Identities = 71/324 (21%), Positives = 109/324 (33%), Gaps = 59/324 (18%)
Query: 169 ESQPSSPSPTPSPSPVLEPGSEPNLAVLS---IPGDTMTTIQMSVEESTPISRETGEPYR 225
E +P P P P P + + +E + + P + + VEE I + E
Sbjct: 10176 EVKPKVPVPAPVPE-IKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLP 10234
Query: 226 LSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEP 285
+ P EPI E E+ P E +P + P + E P VP + P
Sbjct: 10235 VEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTP---VPKKVEAP 10291
Query: 286 EVESSPEL----APPPACPSESP---VPIAPTAQPEELL---NGAPSPPAVDLSPVSEPE 335
+ S ++ P P E+P VP P PE+ + PPA + + E
Sbjct: 10292 PAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKV 10351
Query: 336 EQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEE 395
A + A P +EE E EE EEGE E EE
Sbjct: 10352 SVAFRQEVVVKERLELEVVEAEVEEI--PEEEEFHEVEEYFEEGEFHEV---------EE 10400
Query: 396 LLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVP 455
+ E + +++E ++ E V +++ F+ V
Sbjct: 10401 FIKLE---------------------------QHRVEEEHRVEKVHRVIEVFEAEEVEVF 10433
Query: 456 EVENQPPAGSNPGPESEGSGVPPR 479
E PP GPE +PP+
Sbjct: 10434 EKPKAPP----KGPEISEKIIPPK 10453
Score = 33.1 bits (74), Expect = 2.1
Identities = 33/157 (21%), Positives = 54/157 (34%), Gaps = 12/157 (7%)
Query: 225 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 284
R+ EP + E E ++ L +P P + P P +VP + +
Sbjct: 9546 RVEAEPAEVTER-QEKKIVLKPKIPAKIEEPPPAKVP----------EAPKKIVPEKKVP 9594
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTAS 344
V E PPP P E P+ P +++ PA + ++ K + A
Sbjct: 9595 APVPKK-EKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAV 9653
Query: 345 MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 381
P A P P ++ + + EEE A
Sbjct: 9654 TKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690
Score = 32.7 bits (73), Expect = 2.7
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 29/154 (18%)
Query: 148 RSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQ 207
+S +I D LPGP P + S S +P L+ G P I G +
Sbjct: 15586 KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP------ITGYWLE--- 15636
Query: 208 MSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASH 267
RE G PY P+ + L+ EF+ L
Sbjct: 15637 ---------KREEGSPYWSRVSRAPITKVGLK----------GVEFNVPRLLEGVKYQFR 15677
Query: 268 TVEIHEPNGMVPSEDLEPEVESSPELAP-PPACP 300
+ I+ PSE +PEV P P PP+CP
Sbjct: 15678 AMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCP 15711
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 69.3 bits (168), Expect = 3e-11
Identities = 92/383 (24%), Positives = 123/383 (32%), Gaps = 67/383 (17%)
Query: 107 EEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS 166
EE S A TP P + P T A + P++ + A P P S
Sbjct: 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---S 1067
Query: 167 PSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 226
P+ + P+ PT SP+ + EP ++P T S + P E P
Sbjct: 1068 PAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPASPAAA 1123
Query: 227 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 286
P P A P V P PE +P PTP S + + P PE
Sbjct: 1124 VPTPEEPASPAAAV------PTPEEPAFPAPA-VPTPEESASAAVAVPT---------PE 1167
Query: 287 VESSPELA-PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLS-----------PVSEP 334
+SP A P PA + +A +P P+P A+ + P SE
Sbjct: 1168 ESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEE 1227
Query: 335 EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGE 394
++ PT P+A T TS A A E
Sbjct: 1228 PASLAAAVSNPEEPTSPAAAVPTLEEPTSSA---------------AAVLTPEELSSPAA 1272
Query: 395 ELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAV 454
+ PE PA NLE A+ AV P+ + A A+
Sbjct: 1273 SVPTPEEPASPAAAVSNLEEPASPAAAVPTPE-----------------VAAIPAASVPT 1315
Query: 455 PEVENQPPAGSNPGPESEGSGVP 477
PEV P A P E GVP
Sbjct: 1316 PEVPAIPAAAVPPMEEVSPIGVP 1338
Score = 65.1 bits (157), Expect = 5e-10
Identities = 76/354 (21%), Positives = 115/354 (32%), Gaps = 25/354 (7%)
Query: 28 VPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPK 87
VPT + P P A P E T A P P P P P P
Sbjct: 1020 VPTPEEPTSPAA-----AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1074
Query: 88 RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDD 147
E T EE S A TP P + P A + P++
Sbjct: 1075 PEEPT-----SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
Query: 148 RSQGAIIA---DRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 204
+ A + P P P E S+ P+P P A + P ++ +
Sbjct: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPA-----AAVPTPAESAS 1184
Query: 205 --TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT 262
+ ++EE T + P + P V T +P + S+P + PT
Sbjct: 1185 FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVP-TSEEPASLAAAVSNP-EEPT 1242
Query: 263 PLASHTVEIHEPNGMVPSEDLEPEVESSPELA-PPPACPSESPVPIAPTAQPEELLNGAP 321
A+ + EP + L PE SSP + P P P+ ++ +P P
Sbjct: 1243 SPAAAVPTLEEPTSSAAAV-LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP 1301
Query: 322 SPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 375
+P + S P + + A+ PP + +P P A + + EE
Sbjct: 1302 TPEVAAIPAASVPTPEVPAIPAAAVPP-MEEVSPIGVPFLGVSAHTDSVPISEE 1354
Score = 61.2 bits (147), Expect = 7e-09
Identities = 97/402 (24%), Positives = 132/402 (32%), Gaps = 43/402 (10%)
Query: 103 KDITEEIMSGARTASTP----TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRP 158
+D+T +S A+ P + P+ + ++ E AV A+ P
Sbjct: 894 EDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953
Query: 159 GLPGPEHS-PSESQPSSPSPTPSPSPVLEPGSEPNLAVL--SIPGDTMTTIQMSVEESTP 215
+ P + +P +P+ + EP+ A + S P + + P
Sbjct: 954 EWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013
Query: 216 ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTVEIHEP 274
S P P A P E + + VP E +SP A PTP E P
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSP 1068
Query: 275 NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGA-----PSPPAVDLS 329
VP+ PE +SP A P P E P A PEE + A P PA +
Sbjct: 1069 AAAVPT----PEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Query: 330 PVSEPEEQAKEVTASMAP--PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEA 387
V PEE A A P P P+ T + S A EE E+
Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182
Query: 388 ESEKG-----GEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI----------K 432
S E P S P PA + LE T A SVP +
Sbjct: 1183 ASFAAVVATLEEPTSPAASVPTPAAMVATLE--EFTSPAASVPTSEEPASLAAAVSNPEE 1240
Query: 433 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGS 474
+ AV L + A + E PA S P PE S
Sbjct: 1241 PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS 1282
Score = 52.4 bits (124), Expect = 3e-06
Identities = 95/375 (25%), Positives = 124/375 (33%), Gaps = 63/375 (16%)
Query: 139 VAVIVRPDDRSQGAIIADR--PGLPGPEHSPSESQPSSPSPT-------PSPSPVLEPGS 189
+ V+ RP + + D LP PE S + +P T P P + S
Sbjct: 828 IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887
Query: 190 EPNL-------AVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSP--------EPTPL 233
+L A +S P T+ + +SV E T P +P E
Sbjct: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSA 947
Query: 234 AEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPEL 293
L+ VP +E +P TP TV E PE +SP
Sbjct: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPAT--TVHAPEEPDTAAVRVSTPEEPASPAA 1005
Query: 294 APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSA 353
A P P E P A PEE P+ PA + P EP A V + PT P+A
Sbjct: 1006 AVP--TPEEPTSPAAAVPTPEE-----PTSPAAAVPPPEEPTSPAAAV-PTPEEPTSPAA 1057
Query: 354 TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLE 413
T TSPA + EE A E + PE PA E
Sbjct: 1058 AVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115
Query: 414 AAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANP--AVPEVENQP-PAGSNPGPE 470
A+ AV P+ + A+P AVP E PA + P PE
Sbjct: 1116 EPASPAAAVPTPE---------------------EPASPAAAVPTPEEPAFPAPAVPTPE 1154
Query: 471 SEGSG--VPPRPEEA 483
S P PEE+
Sbjct: 1155 ESASAAVAVPTPEES 1169
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 68.9 bits (167), Expect = 3e-11
Identities = 92/360 (25%), Positives = 129/360 (35%), Gaps = 29/360 (8%)
Query: 163 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 222
P P S PS P PS P + N LS+PG ++ + +
Sbjct: 678 PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737
Query: 223 PYRLSPEPTPLAEPILEVEVTLSKPVPESEF------SSSPLQAPTPLASHTVEIHEPNG 276
P L+P TP P + + T VP F +S ++ S + P G
Sbjct: 738 PI-LAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794
Query: 277 MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL------LNGAPSPPAVDLSP 330
+ P P + P +AP P+ SP P+ +PEEL L P PP P
Sbjct: 795 LPPLPPPPPSGATPPPIAPTGP-PTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852
Query: 331 VSEPEEQA--KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 388
V+ P Q + PP + +++ +EEE EEEEEEEE E E E
Sbjct: 853 VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912
Query: 389 SEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFK 448
E+ EE E + E + + +EL + E + + A
Sbjct: 913 EEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL-EFGTAGG 970
Query: 449 EANPAVPEVENQPPAGSNPGPESEGSGVP-PRPE-----EADETWDSKEDKIHNAENIQP 502
E P PPA P PES P P PE E +E +E A + P
Sbjct: 971 EVEEGAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028
Score = 68.9 bits (167), Expect = 3e-11
Identities = 84/312 (26%), Positives = 108/312 (34%), Gaps = 28/312 (8%)
Query: 119 PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 178
P PP +G P A P + V + + + P PGP P P P P
Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPE-----ELPAAPGPLPPPPPPPPPVPGPV 853
Query: 179 PSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV---EESTPISRETGEPYRLSPEPTPLAE 235
P P L P P + +T I ++ EE E E E E
Sbjct: 854 TLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913
Query: 236 PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI--HEPNGMVPSEDLE-----PEVE 288
E E + E EF + L E E + EDLE EVE
Sbjct: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
Query: 289 SSPELAPPPACPSESPVPIAPT-AQPEELLNGAPSPPAVDLSPVSEP---EEQAKEVTAS 344
PPP P P P +P QPE P P L V EP EE+ + +
Sbjct: 974 EGAP--PPPTLPPALPPPESPPKVQPE------PEPEPGLLLEVEEPGTEEERGADTAPT 1025
Query: 345 MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 404
+AP +PS SPA +E EEE E E+E G +++ PP TP
Sbjct: 1026 LAPEALPSQGEVER-EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPA 1084
Query: 405 PANLSQNLEAAA 416
+ EA A
Sbjct: 1085 EEEMETETEAEA 1096
Score = 45.8 bits (107), Expect = 3e-04
Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 41/321 (12%)
Query: 232 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 291
P P+ + T P P P +AP+P + H P M P V S P
Sbjct: 633 PRVPPLQPMGPTCPTPAPVP-----PPEAPSPFRAPP--FHPPGPM-------PSVGSMP 678
Query: 292 ELAPPPAC---PSESPVPIAPTAQPEELLN-GAPSPPAVDLSPVSEPEEQAKEVTASMAP 347
P P+ PS PVP A P + G P V + P P + ++ P
Sbjct: 679 SAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738
Query: 348 PTIPSATPATA--PSATSPAQ--EEEMEEEEEEEEGEAGEAGEAESEKGG---EELLPPE 400
PS TP P T + ++EE + + E++S+ E LPP
Sbjct: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798
Query: 401 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 460
P P+ + A A + + +EL A L P VP
Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL---PAAPGPLPPPPPPPPPVPGPVTL 855
Query: 461 PPAGSNPGPESEGSGVPPRPEE---------ADETWDSKEDKIHNAENIQPGEQKYEYK- 510
PP P + G G PP EE +DE + +E++ E + E+ +E +
Sbjct: 856 PPPQLVP-EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914
Query: 511 --SDQWKPLNLEEKKRYDREF 529
+++ EE++ ++ EF
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEF 935
Score = 31.6 bits (70), Expect = 6.1
Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 3/42 (7%)
Query: 761 QKEFEKDKDDDEVF---EKKQKEMDEAATAEERGRLKEELEE 799
+++FE++++D+E + E++++E E EE G L+EE EE
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 68.2 bits (165), Expect = 6e-11
Identities = 104/391 (26%), Positives = 140/391 (35%), Gaps = 68/391 (17%)
Query: 31 QQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRER 90
QQ P P P + T + A P + V P P +L Q+ +ER
Sbjct: 645 QQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704
Query: 91 KTIRIRDPNQGGKDITEEIMSGARTASTP---TPPQTGGGLEPQANG---------ETPQ 138
+ I+S A P TP G GL PQA + P
Sbjct: 705 SQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPA 764
Query: 139 VAVIVRPDDRSQGAI-----IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL 193
A + P S ++ + D P LP P + S+P S P V P SEP L
Sbjct: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS-----RPQSVSRPPSEPPL 819
Query: 194 -------AVLSIPGDTMTTIQMSVEE--STPISRETGEPYR-LSPEPTPLAEPILEVE-- 241
A ++PG + Q+ V S P G P L P+ P P+
Sbjct: 820 HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
Query: 242 --VTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 299
+ S V S +SS L APTP + ++ G S P + PE A PP
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTP-SDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938
Query: 300 PSES------PVPIAPTAQPEELLN----------------GAPSPP--AVDLSPVSEPE 335
P + P P P QP+ LL GAP+ P + L P++ P
Sbjct: 939 PPRTFQMVTTPFPALP--QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPA 996
Query: 336 EQAKEVTASMAP---PTIPSATPATAPSATS 363
A + + AP PT PS PA AP A +
Sbjct: 997 --ASVLVSGQAPSGTPTAPSHAPAPAPMAAT 1025
Score = 59.3 bits (142), Expect = 3e-08
Identities = 105/454 (23%), Positives = 179/454 (39%), Gaps = 81/454 (17%)
Query: 60 PAQ----GVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGART 115
PAQ G QF APA L Q + + + P+ GG+ I I++
Sbjct: 461 PAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNL 520
Query: 116 ASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSP 175
A P G L P + + + + P Q A+ P P++SQP+
Sbjct: 521 AG---PLSLGPVLAPHSGAHSAHI-LSAAPIQVGQPALF-QMPVSLAAGSLPTQSQPAPA 575
Query: 176 SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAE 235
P + + VL+ + P AV + T V+ +TP + TGE A
Sbjct: 576 GP--AATTVLQGVTLPPSAVAML-----NTPDGLVQPATPAAA-TGE-----------AA 616
Query: 236 PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP 295
P+L V+ P P++ P TPL P G+ + +P +P+ A
Sbjct: 617 PVLTVQ-----PAPQA-----PPAVSTPL---------PLGLQQPQAQQPPQAPTPQAAA 657
Query: 296 PPACPSESPVPIAPTAQPEELLNGAP---SPPAV---DLSPVSEPEEQAKEVTASMAPP- 348
PP + P P + PE+++ G P +P A+ D + P+E++++ ++ P
Sbjct: 658 PPQATTPQPSP-GLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
Query: 349 TIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLP---------P 399
++P++ +AP PAQ+ + G +A ++++ +P P
Sbjct: 717 SVPASVIVSAP---PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGP 773
Query: 400 ESTP-----IPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAV 454
S+P P S +L + T+ P R + + + + +A P +
Sbjct: 774 SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPP--PQAPPTL 831
Query: 455 P---EVENQ---PPAGSNPGPESEGSGVPP-RPE 481
P ++NQ PP SNP P + G PP RP+
Sbjct: 832 PGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865
Score = 57.8 bits (138), Expect = 8e-08
Identities = 127/531 (23%), Positives = 183/531 (34%), Gaps = 86/531 (16%)
Query: 4 PSQISYPASQGAYYIPGQGRSTYVVPT-----QQYPVQPGA-------PGFYPGASPTEF 51
P+ P S A +P Q + P Q + P A G A+P
Sbjct: 552 PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAA 611
Query: 52 GTYAGAYYPAQGVQQFPTGVA-PAPVLMNQP----------PQIAPKRERKTIRIRDPNQ 100
A Q Q P V+ P P+ + QP PQ A + T + P+
Sbjct: 612 TGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQ---PSP 668
Query: 101 GGKDITEEIMSGARTASTPTPPQTGGGLE---PQANGETPQVA-----------VIVRP- 145
G E+I+ G ++TPT T L+ PQ + P A ++ P
Sbjct: 669 GLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP 728
Query: 146 --DDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPG--SEPNLAVLSIPGD 201
D + +A GL GP+ S++ P+ P+ +P+ PG S P+L + GD
Sbjct: 729 PAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGD 787
Query: 202 TM------TTIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPILE----VEVTLSKPVP 249
+ T S S P +SR EP L P P P A P L ++ L P P
Sbjct: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEP-PLHPCPPPQAPPTLPGIFVIQNQLGVPPP 846
Query: 250 ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 309
S + +P P + P G +P P +S +A S P P
Sbjct: 847 AS--NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
Query: 310 TAQ----PEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT--PATAPSATS 363
Q P + + +P+PP L V EP APP P T T P
Sbjct: 905 DFQLQFPPSQGPHKSPTPPPT-LHLVPEPA----------APPPPPPRTFQMVTTPFPAL 953
Query: 364 PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVS 423
P + +E + G +++ GG P ST + S + Q
Sbjct: 954 PQPKALLERFHQVPSGII-----LQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSG 1008
Query: 424 VPKRRRKIKELNKKEAVG--DLLDAFKEANPA-VPEVENQPPAGSNPGPES 471
P A G LL A +A + +P + A S PG S
Sbjct: 1009 TPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPS 1059
Score = 33.9 bits (76), Expect = 1.2
Identities = 82/378 (21%), Positives = 126/378 (33%), Gaps = 64/378 (16%)
Query: 144 RPDD-----RSQGA-IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEP---------G 188
+PD+ RS G I A G P H P S S+P + P P L G
Sbjct: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSS--SAPGASTQPPPHLPTKLVIRHGGAG 1254
Query: 189 SEPNL-------AVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI-LEV 240
P++ ++ S + + +E P+ P + + + + ++
Sbjct: 1255 GSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQ 1314
Query: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
E LSK V + P+ P P + T+++ EP P + PPPA P
Sbjct: 1315 EAGLSKVVHNTALD--PVHQPPPPPA-TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371
Query: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
P L AP P + L K ++ P P TPA
Sbjct: 1372 ERKP------------LGTAPHCPRLPL---------RKTYRENVGGPGAPEGTPAGRAR 1410
Query: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420
SPA + +E G E E E L P P PA + +
Sbjct: 1411 GGSPAPLP--AKVDEATSGLIRELAAVEDELYQRMLKGP--PPEPAASAAQGTGDPDWEA 1466
Query: 421 AVSVPKRRRKIKELNKKEAV--------GDLLDAFKEANPAVPEVENQP---PAGSNPGP 469
P +RRK + + +A L + + A ++ ++ P PA S P
Sbjct: 1467 PGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA 1526
Query: 470 ESEGSGVPPRPEEADETW 487
S G+ P P E +
Sbjct: 1527 ASAGTPASPPPLHRPEAY 1544
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 67.8 bits (164), Expect = 8e-11
Identities = 108/518 (20%), Positives = 164/518 (31%), Gaps = 60/518 (11%)
Query: 19 PGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLM 78
P +S P + P P P P T P + PT PAP
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 79 NQPPQIAPKRERKTIRIRD----PNQGGKDITEEIMSGARTASTPTP----PQTGGGLEP 130
+P APK+ T P + T+E PT P T P
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405
Query: 131 QANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLE 186
P P + A + P P+ + P P+PT P+P+ +
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 187 PG-SEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGE------PYRLSP----EPTPL 233
P + P + P +T T + +TP ++ T E P L+P EPTP
Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 525
Query: 234 AE-------PILEVEVTLSKPVPESEFSSSPL--QAPTPLASHTVEIHEPNGMVPSEDLE 284
P T +P P + +P + P P P G P+ E
Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTAS 344
P + + AP P+ + P + T P+P + + P+E A
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAPTTPKEPAPTTPKE 638
Query: 345 MAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLP---- 398
AP T P T P+ T+P + E +G + + +E P
Sbjct: 639 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 698
Query: 399 -PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK--EAVGDLLDAFKEANPAVP 455
P T E T VS P ++ ++K E+ +L A P
Sbjct: 699 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL-----SAEPTPK 753
Query: 456 EVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 493
+EN P PG + + +PE D ++
Sbjct: 754 ALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 788
Score = 64.3 bits (155), Expect = 8e-10
Identities = 157/723 (21%), Positives = 221/723 (30%), Gaps = 89/723 (12%)
Query: 73 PAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQA 132
P P +P PK T P + S T P P T
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275
Query: 133 NGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLEPG 188
P P P P+ P+ + P P+PT P+P+ EP
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPA 334
Query: 189 SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPV 248
+ P + T +TP +E P PT EP T +P
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEPS---PTTPKEPA 389
Query: 249 P---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPP------PAC 299
P +S +++ APT S EP+ P+ EP + E AP P
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTTTKEPAPTTPKEPAPTTPKKPAPTT 446
Query: 300 PSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAP 359
P E P P P +P P+P + P+E A T PT P T P
Sbjct: 447 PKE-PAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPTTP 503
Query: 360 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAAT- 418
+P EE+ EE + EE P +TP A + E A T
Sbjct: 504 EKPAPTTPEELAPTTPEE----------PTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 551
Query: 419 -QVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPE----VENQPPAGSNPGPES 471
+ A + PK KE G KE P P+ E P P +
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 472 EGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLL 531
P P+ T KE + P K + +P KK +E
Sbjct: 612 CDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670
Query: 532 GFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTL 591
S + P + A TP P T + P+ P + T
Sbjct: 671 TTTKGPTSTTSDKPAP---TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT 727
Query: 592 STRGPP--RGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649
+T+ P P P A P+ + P KEP + K A KP
Sbjct: 728 TTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEP-----------GVPTTKTPAATKP 775
Query: 650 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709
TA DK + +DL + TP+ K + A TE+ +
Sbjct: 776 EMTTTAKDK---------TTERDL---------RTTPETTTAAPKMTKETATTTEKTTES 817
Query: 710 VIDLIFEKAIS---EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEK 766
I + S + + +A KV TT+K T ++N+ +E K
Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE----IMNK-PEETAK 872
Query: 767 DKD 769
KD
Sbjct: 873 PKD 875
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 118 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 174
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 79 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 118
Query: 175 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 233
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 119 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 172
Query: 234 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 173 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 232
Query: 283 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 328
++S+P PA + P P T +P P+P P
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292
Query: 329 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 381
S + P+E A AP PT P T P +P +E +E A
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352
Query: 382 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 432
+ + K P E P P + +A T P +
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 433 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 490
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 413 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 67.8 bits (164), Expect = 8e-11
Identities = 108/518 (20%), Positives = 164/518 (31%), Gaps = 60/518 (11%)
Query: 19 PGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLM 78
P +S P + P P P P T P + PT PAP
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Query: 79 NQPPQIAPKRERKTIRIRD----PNQGGKDITEEIMSGARTASTPTP----PQTGGGLEP 130
+P APK+ T P + T+E PT P T P
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446
Query: 131 QANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLE 186
P P + A + P P+ + P P+PT P+P+ +
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 187 PG-SEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGE------PYRLSP----EPTPL 233
P + P + P +T T + +TP ++ T E P L+P EPTP
Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 566
Query: 234 AE-------PILEVEVTLSKPVPESEFSSSPL--QAPTPLASHTVEIHEPNGMVPSEDLE 284
P T +P P + +P + P P P G P+ E
Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTAS 344
P + + AP P+ + P + T P+P + + P+E A
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAPTTPKEPAPTTPKE 679
Query: 345 MAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLP---- 398
AP T P T P+ T+P + E +G + + +E P
Sbjct: 680 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 739
Query: 399 -PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK--EAVGDLLDAFKEANPAVP 455
P T E T VS P ++ ++K E+ +L A P
Sbjct: 740 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL-----SAEPTPK 794
Query: 456 EVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 493
+EN P PG + + +PE D ++
Sbjct: 795 ALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 829
Score = 64.3 bits (155), Expect = 8e-10
Identities = 157/723 (21%), Positives = 221/723 (30%), Gaps = 89/723 (12%)
Query: 73 PAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQA 132
P P +P PK T P + S T P P T
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316
Query: 133 NGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLEPG 188
P P P P+ P+ + P P+PT P+P+ EP
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPA 375
Query: 189 SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPV 248
+ P + T +TP +E P PT EP T +P
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEPS---PTTPKEPA 430
Query: 249 P---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPP------PAC 299
P +S +++ APT S EP+ P+ EP + E AP P
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTTTKEPAPTTPKEPAPTTPKKPAPTT 487
Query: 300 PSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAP 359
P E P P P +P P+P + P+E A T PT P T P
Sbjct: 488 PKE-PAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPTTP 544
Query: 360 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAAT- 418
+P EE+ EE + EE P +TP A + E A T
Sbjct: 545 EKPAPTTPEELAPTTPEE----------PTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 592
Query: 419 -QVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPE----VENQPPAGSNPGPES 471
+ A + PK KE G KE P P+ E P P +
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 472 EGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLL 531
P P+ T KE + P K + +P KK +E
Sbjct: 653 CDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 711
Query: 532 GFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTL 591
S + P + A TP P T + P+ P + T
Sbjct: 712 TTTKGPTSTTSDKPAP---TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT 768
Query: 592 STRGPP--RGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649
+T+ P P P A P+ + P KEP + K A KP
Sbjct: 769 TTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEP-----------GVPTTKTPAATKP 816
Query: 650 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709
TA DK + +DL + TP+ K + A TE+ +
Sbjct: 817 EMTTTAKDK---------TTERDL---------RTTPETTTAAPKMTKETATTTEKTTES 858
Query: 710 VIDLIFEKAIS---EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEK 766
I + S + + +A KV TT+K T ++N+ +E K
Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE----IMNK-PEETAK 913
Query: 767 DKD 769
KD
Sbjct: 914 PKD 916
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 118 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 174
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 120 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 159
Query: 175 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 233
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 160 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 213
Query: 234 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 214 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 273
Query: 283 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 328
++S+P PA + P P T +P P+P P
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333
Query: 329 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 381
S + P+E A AP PT P T P +P +E +E A
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393
Query: 382 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 432
+ + K P E P P + +A T P +
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 433 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 490
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 454 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 67.8 bits (164), Expect = 8e-11
Identities = 108/518 (20%), Positives = 164/518 (31%), Gaps = 60/518 (11%)
Query: 19 PGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLM 78
P +S P + P P P P T P + PT PAP
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Query: 79 NQPPQIAPKRERKTIRIRD----PNQGGKDITEEIMSGARTASTPTP----PQTGGGLEP 130
+P APK+ T P + T+E PT P T P
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498
Query: 131 QANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLE 186
P P + A + P P+ + P P+PT P+P+ +
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 187 PG-SEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGE------PYRLSP----EPTPL 233
P + P + P +T T + +TP ++ T E P L+P EPTP
Sbjct: 559 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 618
Query: 234 AE-------PILEVEVTLSKPVPESEFSSSPL--QAPTPLASHTVEIHEPNGMVPSEDLE 284
P T +P P + +P + P P P G P+ E
Sbjct: 619 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 678
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTAS 344
P + + AP P+ + P + T P+P + + P+E A
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAPTTPKEPAPTTPKE 731
Query: 345 MAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLP---- 398
AP T P T P+ T+P + E +G + + +E P
Sbjct: 732 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 791
Query: 399 -PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK--EAVGDLLDAFKEANPAVP 455
P T E T VS P ++ ++K E+ +L A P
Sbjct: 792 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL-----SAEPTPK 846
Query: 456 EVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 493
+EN P PG + + +PE D ++
Sbjct: 847 ALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 881
Score = 64.3 bits (155), Expect = 8e-10
Identities = 157/723 (21%), Positives = 221/723 (30%), Gaps = 89/723 (12%)
Query: 73 PAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQA 132
P P +P PK T P + S T P P T
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368
Query: 133 NGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLEPG 188
P P P P+ P+ + P P+PT P+P+ EP
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPA 427
Query: 189 SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPV 248
+ P + T +TP +E P PT EP T +P
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEPS---PTTPKEPA 482
Query: 249 P---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPP------PAC 299
P +S +++ APT S EP+ P+ EP + E AP P
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTTTKEPAPTTPKEPAPTTPKKPAPTT 539
Query: 300 PSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAP 359
P E P P P +P P+P + P+E A T PT P T P
Sbjct: 540 PKE-PAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPTTP 596
Query: 360 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAAT- 418
+P EE+ EE + EE P +TP A + E A T
Sbjct: 597 EKPAPTTPEELAPTTPEE----------PTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 644
Query: 419 -QVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPE----VENQPPAGSNPGPES 471
+ A + PK KE G KE P P+ E P P +
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704
Query: 472 EGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLL 531
P P+ T KE + P K + +P KK +E
Sbjct: 705 CDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 763
Query: 532 GFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTL 591
S + P + A TP P T + P+ P + T
Sbjct: 764 TTTKGPTSTTSDKPAP---TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT 820
Query: 592 STRGPP--RGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649
+T+ P P P A P+ + P KEP + K A KP
Sbjct: 821 TTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEP-----------GVPTTKTPAATKP 868
Query: 650 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709
TA DK + +DL + TP+ K + A TE+ +
Sbjct: 869 EMTTTAKDK---------TTERDL---------RTTPETTTAAPKMTKETATTTEKTTES 910
Query: 710 VIDLIFEKAIS---EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEK 766
I + S + + +A KV TT+K T ++N+ +E K
Sbjct: 911 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE----IMNK-PEETAK 965
Query: 767 DKD 769
KD
Sbjct: 966 PKD 968
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 118 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 174
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 172 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 211
Query: 175 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 233
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 212 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 265
Query: 234 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 266 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 325
Query: 283 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 328
++S+P PA + P P T +P P+P P
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 329 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 381
S + P+E A AP PT P T P +P +E +E A
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445
Query: 382 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 432
+ + K P E P P + +A T P +
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 433 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 490
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 506 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 67.8 bits (164), Expect = 8e-11
Identities = 108/518 (20%), Positives = 164/518 (31%), Gaps = 60/518 (11%)
Query: 19 PGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLM 78
P +S P + P P P P T P + PT PAP
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Query: 79 NQPPQIAPKRERKTIRIRD----PNQGGKDITEEIMSGARTASTPTP----PQTGGGLEP 130
+P APK+ T P + T+E PT P T P
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539
Query: 131 QANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLE 186
P P + A + P P+ + P P+PT P+P+ +
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 187 PG-SEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGE------PYRLSP----EPTPL 233
P + P + P +T T + +TP ++ T E P L+P EPTP
Sbjct: 600 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 659
Query: 234 AE-------PILEVEVTLSKPVPESEFSSSPL--QAPTPLASHTVEIHEPNGMVPSEDLE 284
P T +P P + +P + P P P G P+ E
Sbjct: 660 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719
Query: 285 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTAS 344
P + + AP P+ + P + T P+P + + P+E A
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAPTTPKEPAPTTPKE 772
Query: 345 MAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLP---- 398
AP T P T P+ T+P + E +G + + +E P
Sbjct: 773 PAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 832
Query: 399 -PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK--EAVGDLLDAFKEANPAVP 455
P T E T VS P ++ ++K E+ +L A P
Sbjct: 833 EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL-----SAEPTPK 887
Query: 456 EVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 493
+EN P PG + + +PE D ++
Sbjct: 888 ALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 922
Score = 64.3 bits (155), Expect = 8e-10
Identities = 157/723 (21%), Positives = 221/723 (30%), Gaps = 89/723 (12%)
Query: 73 PAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQA 132
P P +P PK T P + S T P P T
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409
Query: 133 NGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLEPG 188
P P P P+ P+ + P P+PT P+P+ EP
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPA 468
Query: 189 SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPV 248
+ P + T +TP +E P PT EP T +P
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEPS---PTTPKEPA 523
Query: 249 P---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPP------PAC 299
P +S +++ APT S EP+ P+ EP + E AP P
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPS---PTTTKEPAPTTPKEPAPTTPKKPAPTT 580
Query: 300 PSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAP 359
P E P P P +P P+P + P+E A T PT P T P
Sbjct: 581 PKE-PAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPTTP 637
Query: 360 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAAT- 418
+P EE+ EE + EE P +TP A + E A T
Sbjct: 638 EKPAPTTPEELAPTTPEE----------PTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 685
Query: 419 -QVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPE----VENQPPAGSNPGPES 471
+ A + PK KE G KE P P+ E P P +
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745
Query: 472 EGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLL 531
P P+ T KE + P K + +P KK +E
Sbjct: 746 CDKPAPTTPKGTAPT-TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 804
Query: 532 GFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTL 591
S + P + A TP P T + P+ P + T
Sbjct: 805 TTTKGPTSTTSDKPAP---TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT 861
Query: 592 STRGPP--RGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649
+T+ P P P A P+ + P KEP + K A KP
Sbjct: 862 TTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEP-----------GVPTTKTPAATKP 909
Query: 650 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709
TA DK + +DL + TP+ K + A TE+ +
Sbjct: 910 EMTTTAKDK---------TTERDL---------RTTPETTTAAPKMTKETATTTEKTTES 951
Query: 710 VIDLIFEKAIS---EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEK 766
I + S + + +A KV TT+K T ++N+ +E K
Sbjct: 952 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE----IMNK-PEETAK 1006
Query: 767 DKD 769
KD
Sbjct: 1007 PKD 1009
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 118 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 174
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 213 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 252
Query: 175 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 233
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 253 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 306
Query: 234 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 307 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 366
Query: 283 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 328
++S+P PA + P P T +P P+P P
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 329 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 381
S + P+E A AP PT P T P +P +E +E A
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486
Query: 382 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 432
+ + K P E P P + +A T P +
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 433 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 490
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 547 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,374,445
Number of Sequences: 37866
Number of extensions: 4195420
Number of successful extensions: 50420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 413
Number of HSP's successfully gapped in prelim test: 1881
Number of HSP's that attempted gapping in prelim test: 27166
Number of HSP's gapped (non-prelim): 15701
length of query: 1512
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1397
effective length of database: 13,892,928
effective search space: 19408420416
effective search space used: 19408420416
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.