BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] (1599 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 3190 0.0 gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 3190 0.0 gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 3010 0.0 gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 2849 0.0 gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0 gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 1273 0.0 gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 196 2e-49 gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 196 2e-49 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 1e-20 gi|163965366 nascent polypeptide-associated complex alpha subuni... 94 1e-18 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 85 5e-16 gi|150170670 piccolo isoform 2 [Homo sapiens] 84 1e-15 gi|150378539 piccolo isoform 1 [Homo sapiens] 84 1e-15 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 84 1e-15 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 84 1e-15 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 84 1e-15 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 84 1e-15 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 83 2e-15 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 82 4e-15 gi|112421108 capicua homolog [Homo sapiens] 82 4e-15 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 81 7e-15 gi|33386693 poly(A) binding protein interacting protein 1 isofor... 81 9e-15 gi|17511255 poly(A) binding protein interacting protein 1 isofor... 81 9e-15 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 79 3e-14 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 79 4e-14 gi|169212085 PREDICTED: similar to poly(A) binding protein inter... 78 8e-14 gi|239752553 PREDICTED: similar to poly(A) binding protein inter... 78 8e-14 gi|89041275 PREDICTED: similar to poly(A) binding protein intera... 78 8e-14 gi|34452730 poly(A) binding protein interacting protein 1 isofor... 77 1e-13 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 77 1e-13 >gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 3190 bits (8271), Expect = 0.0 Identities = 1599/1599 (100%), Positives = 1599/1599 (100%) Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS Sbjct: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY Sbjct: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120 Query: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI Sbjct: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180 Query: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI Sbjct: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240 Query: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES Sbjct: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300 Query: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE Sbjct: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360 Query: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE Sbjct: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420 Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG Sbjct: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480 Query: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA Sbjct: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540 Query: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ Sbjct: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600 Query: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI Sbjct: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660 Query: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL Sbjct: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720 Query: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM Sbjct: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780 Query: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR Sbjct: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840 Query: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK Sbjct: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900 Query: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN Sbjct: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960 Query: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV Sbjct: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020 Query: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS Sbjct: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080 Query: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV Sbjct: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140 Query: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ Sbjct: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200 Query: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK Sbjct: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260 Query: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY Sbjct: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320 Query: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL Sbjct: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380 Query: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS Sbjct: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440 Query: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD Sbjct: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500 Query: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF Sbjct: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560 Query: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN Sbjct: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599 >gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 3190 bits (8271), Expect = 0.0 Identities = 1599/1599 (100%), Positives = 1599/1599 (100%) Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS Sbjct: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY Sbjct: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120 Query: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI Sbjct: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180 Query: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI Sbjct: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240 Query: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES Sbjct: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300 Query: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE Sbjct: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360 Query: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE Sbjct: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420 Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG Sbjct: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480 Query: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA Sbjct: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540 Query: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ Sbjct: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600 Query: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI Sbjct: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660 Query: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL Sbjct: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720 Query: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM Sbjct: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780 Query: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR Sbjct: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840 Query: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK Sbjct: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900 Query: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN Sbjct: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960 Query: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV Sbjct: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020 Query: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS Sbjct: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080 Query: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV Sbjct: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140 Query: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ Sbjct: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200 Query: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK Sbjct: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260 Query: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY Sbjct: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320 Query: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL Sbjct: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380 Query: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS Sbjct: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440 Query: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD Sbjct: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500 Query: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF Sbjct: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560 Query: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN Sbjct: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599 >gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 isoform 2 [Homo sapiens] Length = 1512 Score = 3010 bits (7804), Expect = 0.0 Identities = 1512/1512 (100%), Positives = 1512/1512 (100%) Query: 88 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 147 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP Sbjct: 1 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 60 Query: 148 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 207 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT Sbjct: 61 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 120 Query: 208 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 267 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS Sbjct: 121 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 180 Query: 268 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 327 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV Sbjct: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240 Query: 328 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 387 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP Sbjct: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300 Query: 388 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 447 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS Sbjct: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360 Query: 448 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 507 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV Sbjct: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420 Query: 508 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 567 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP Sbjct: 421 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 480 Query: 568 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 627 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM Sbjct: 481 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 540 Query: 628 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 687 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG Sbjct: 541 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 600 Query: 688 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 747 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR Sbjct: 601 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 660 Query: 748 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 807 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS Sbjct: 661 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 720 Query: 808 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 867 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE Sbjct: 721 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 780 Query: 868 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 927 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH Sbjct: 781 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 840 Query: 928 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 987 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG Sbjct: 841 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 900 Query: 988 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 1047 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV Sbjct: 901 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 960 Query: 1048 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1107 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD Sbjct: 961 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1020 Query: 1108 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1167 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG Sbjct: 1021 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1080 Query: 1168 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1227 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL Sbjct: 1081 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1140 Query: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1287 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL Sbjct: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1200 Query: 1288 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1347 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI Sbjct: 1201 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1260 Query: 1348 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1407 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL Sbjct: 1261 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1320 Query: 1408 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1467 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN Sbjct: 1321 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1380 Query: 1468 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1527 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA Sbjct: 1381 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1440 Query: 1528 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1587 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK Sbjct: 1441 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1500 Query: 1588 WLREAEEESDHN 1599 WLREAEEESDHN Sbjct: 1501 WLREAEEESDHN 1512 Score = 33.5 bits (75), Expect = 1.7 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%) Query: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57 P S P P+PSP L + P PG T + + + +TP R+ P R Sbjct: 172 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 227 Query: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113 P P+ A + P S+ P Q P + I G S Sbjct: 228 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282 Query: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173 + P + + P P SP P ++ G AP+P ++ P Sbjct: 283 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 330 Query: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233 + +P + K++T + + PT P P A Q + + Sbjct: 331 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 374 Query: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292 + +G A G E E P +P P+ S LE + +AV S+P Sbjct: 375 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 431 Query: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349 +++ +E+ G+ E P + S P PESE S P +A Sbjct: 432 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 485 Query: 350 PLASHTVEIHEPNGMVPSE 368 S +IH + P E Sbjct: 486 TWDSKEDKIHNAENIQPGE 504 >gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 isoform 3 [Homo sapiens] Length = 1435 Score = 2849 bits (7386), Expect = 0.0 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%) Query: 165 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 224 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP Sbjct: 1 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60 Query: 225 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 284 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS Sbjct: 61 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120 Query: 285 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 344 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP Sbjct: 121 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180 Query: 345 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 404 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL Sbjct: 181 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240 Query: 405 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 464 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE Sbjct: 241 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300 Query: 465 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK Sbjct: 301 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360 Query: 525 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 584 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA Sbjct: 361 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420 Query: 585 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 644 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA Sbjct: 421 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480 Query: 645 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 704 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS Sbjct: 481 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540 Query: 705 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 764 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV Sbjct: 541 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600 Query: 765 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 824 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA Sbjct: 601 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660 Query: 825 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 884 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL Sbjct: 661 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720 Query: 885 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 944 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK Sbjct: 721 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780 Query: 945 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 1004 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ Sbjct: 781 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840 Query: 1005 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 1064 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI Sbjct: 841 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900 Query: 1065 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 1124 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS Sbjct: 901 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960 Query: 1125 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1184 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR Sbjct: 961 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020 Query: 1185 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1244 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK Sbjct: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080 Query: 1245 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1304 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL Sbjct: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140 Query: 1305 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1364 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK Sbjct: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200 Query: 1365 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1424 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY Sbjct: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260 Query: 1425 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1484 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT Sbjct: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320 Query: 1485 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1544 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM Sbjct: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380 Query: 1545 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN Sbjct: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435 Score = 33.5 bits (75), Expect = 1.7 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%) Query: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57 P S P P+PSP L + P PG T + + + +TP R+ P R Sbjct: 95 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 150 Query: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113 P P+ A + P S+ P Q P + I G S Sbjct: 151 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205 Query: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173 + P + + P P SP P ++ G AP+P ++ P Sbjct: 206 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 253 Query: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233 + +P + K++T + + PT P P A Q + + Sbjct: 254 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 297 Query: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292 + +G A G E E P +P P+ S LE + +AV S+P Sbjct: 298 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 354 Query: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349 +++ +E+ G+ E P + S P PESE S P +A Sbjct: 355 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 408 Query: 350 PLASHTVEIHEPNGMVPSE 368 S +IH + P E Sbjct: 409 TWDSKEDKIHNAENIQPGE 427 >gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 isoform 4 [Homo sapiens] Length = 1403 Score = 2784 bits (7218), Expect = 0.0 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%) Query: 197 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 256 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE Sbjct: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 Query: 257 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE Sbjct: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 Query: 317 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 376 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES Sbjct: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 Query: 377 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT Sbjct: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 Query: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 496 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS Sbjct: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 Query: 497 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 556 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP Sbjct: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 Query: 557 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 616 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF Sbjct: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 Query: 617 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 676 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT Sbjct: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 Query: 677 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 736 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP Sbjct: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 Query: 737 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 796 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG Sbjct: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 Query: 797 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 856 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD Sbjct: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 Query: 857 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 916 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM Sbjct: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 Query: 917 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 976 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR Sbjct: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 Query: 977 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 1036 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP Sbjct: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 Query: 1037 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1096 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG Sbjct: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 Query: 1097 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1156 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD Sbjct: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 Query: 1157 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1216 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR Sbjct: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 Query: 1217 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1276 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF Sbjct: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 Query: 1277 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1336 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV Sbjct: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 Query: 1337 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1396 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW Sbjct: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 Query: 1397 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1456 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS Sbjct: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 Query: 1457 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1516 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC Sbjct: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 Query: 1517 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1576 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG Sbjct: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 Query: 1577 VALKSVTAFFKWLREAEEESDHN 1599 VALKSVTAFFKWLREAEEESDHN Sbjct: 1381 VALKSVTAFFKWLREAEEESDHN 1403 Score = 33.5 bits (75), Expect = 1.7 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%) Query: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57 P S P P+PSP L + P PG T + + + +TP R+ P R Sbjct: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 118 Query: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113 P P+ A + P S+ P Q P + I G S Sbjct: 119 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173 Query: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173 + P + + P P SP P ++ G AP+P ++ P Sbjct: 174 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 221 Query: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233 + +P + K++T + + PT P P A Q + + Sbjct: 222 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 265 Query: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292 + +G A G E E P +P P+ S LE + +AV S+P Sbjct: 266 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 322 Query: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349 +++ +E+ G+ E P + S P PESE S P +A Sbjct: 323 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 376 Query: 350 PLASHTVEIHEPNGMVPSE 368 S +IH + P E Sbjct: 377 TWDSKEDKIHNAENIQPGE 395 >gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo sapiens] Length = 1585 Score = 1273 bits (3294), Expect = 0.0 Identities = 808/1669 (48%), Positives = 1006/1669 (60%), Gaps = 194/1669 (11%) Query: 41 MNTPSQPRQHFYPS-RAQPPSSAASRVQSAAPARPG---PAAHVYPAGSQVMMIPS-QIS 95 MN+ Q R F+ + QPP A+ S+ RPG P A VY A +MM+ + Sbjct: 1 MNSQPQTRSPFFQRPQIQPPR--ATIPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMP 57 Query: 96 YPASQGAYYIPGQGRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQG 150 YP QG Y Q R + YV P QQYPVQP PG FYPG P +F Y +YP+Q Sbjct: 58 YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP 117 Query: 151 VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA---------- 200 V Q + P QPP KRE+KTIRIRDPNQGGKDITEEIMSG Sbjct: 118 VYQSAPIIVPT---QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172 Query: 201 RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 260 R STPTPPQ L Q +P V V + A +A + E +P Sbjct: 173 RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223 Query: 261 SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 302 SPSPVL E + ++A L +P T++++ S + Sbjct: 224 PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283 Query: 303 ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 349 S + +P SP + P L S P+P +E + P Sbjct: 284 SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343 Query: 350 ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 405 PL S T I+E NG+ SE L ES E+ P + I E L Sbjct: 344 PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400 Query: 406 GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 461 P+P ++P + P T +PP P PA A + +SP+ + +EE+E Sbjct: 401 CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456 Query: 462 E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 510 E+ E E E++ EE+L ++ +P+PA Q+A++ Sbjct: 457 SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504 Query: 511 VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 566 VPK +K K+ + +E + L+ E ++ +V + G PE + S + + Sbjct: 505 VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563 Query: 567 PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 611 + +E + E + AE++ GE + +K + WKP + E KK+ Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623 Query: 612 YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 669 YDREFLL FQF+ A +QKPEGLP ISDVVLDK N K P+R LDP L GPDFTP+ Sbjct: 624 YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680 Query: 670 FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 729 FA+ GR T RG P +G RRSQ G R+EPRKII TV + ED+ L K Sbjct: 681 FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728 Query: 730 AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 789 AE AWKPS KR D +D + KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D Sbjct: 729 AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783 Query: 790 TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 849 TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP +KP TVNFRKLLLNRCQK Sbjct: 784 TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843 Query: 850 EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 909 EFEKDK DD+VFEKKQKE++ A+ EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK Sbjct: 844 EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903 Query: 910 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 969 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+ Sbjct: 904 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963 Query: 970 KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 1029 KTSSRIRFMLQDV+DLR NWV RR DQGPKTI+QIHKEA++EE E KVQQLM K + Sbjct: 964 KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021 Query: 1030 KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 1089 KRR G+ VD+GGWNTV +K SR +D S+ KITKP +ID QL Sbjct: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071 Query: 1090 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 1141 SWGKGSSGG+ A +D A R + S+LNRFSALQ P+ ST D+RR + Sbjct: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127 Query: 1142 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200 R S+ RE+ +K R RGG D LD ++ EE+ RE Sbjct: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176 Query: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1256 + L + + RE+A P +S + KAALSEEELE+KSK+II+E+LH+ Sbjct: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236 Query: 1257 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1316 ND KEA+QCV+EL + LL +FVR GVESTLERS I R+HMGQLL+QL+ + LS ++ Sbjct: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296 Query: 1317 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1376 +G E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL E +KPL P+G+A LL Sbjct: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356 Query: 1377 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1433 EIL LLCK M KKVG LWREA LSWK+FLPEG+D+ F+ EQK+++ + SEA Sbjct: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416 Query: 1434 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1492 ++ L +EEL ++LEKL+ E +N +++FDW+EANL E Q+ S T +RALMTAVC +AII Sbjct: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476 Query: 1493 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1550 + + RVD AV+K R +L KYL D +KELQALYALQA +V L+QP NLLRMFFD LY Sbjct: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536 Query: 1551 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599 DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N Sbjct: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585 >gi|110630018 eukaryotic translation initiation factor 4 gamma, 2 isoform 2 [Homo sapiens] Length = 869 Score = 196 bits (498), Expect = 2e-49 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%) Query: 707 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 763 G R P+ T +E + + A W P+ D A+ + D +FR+ Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80 Query: 764 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 823 VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139 Query: 824 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875 A P + P + FR+LL+++ Q EFE + +V++K++ + Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192 Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 929 L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+ Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247 Query: 930 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 988 E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307 Query: 989 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 1039 +WVPR+ D GPKTI+QI ++A +++ I SD GP PP Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359 Score = 113 bits (282), Expect = 2e-24 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%) Query: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1286 P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + + Sbjct: 492 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 551 Query: 1287 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1346 L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+ Sbjct: 552 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 611 Query: 1347 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1406 + V + EL +PL G L L L L K + + L++++ ++ ++ Sbjct: 612 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 666 Query: 1407 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1465 LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+ Sbjct: 667 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 717 Query: 1466 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1510 N+S + V V LMT+ S+ + L + +L + + Sbjct: 718 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777 Query: 1511 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1569 +QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+ Sbjct: 778 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 836 Query: 1570 AEQQGKGVALKSVTAFFKWLREAEEE 1595 E GKG AL V + WL AEEE Sbjct: 837 QEFPGKGKALFQVNQWLTWLETAEEE 862 >gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 isoform 1 [Homo sapiens] Length = 907 Score = 196 bits (498), Expect = 2e-49 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%) Query: 707 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 763 G R P+ T +E + + A W P+ D A+ + D +FR+ Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80 Query: 764 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 823 VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139 Query: 824 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875 A P + P + FR+LL+++ Q EFE + +V++K++ + Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192 Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 929 L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+ Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247 Query: 930 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 988 E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307 Query: 989 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 1039 +WVPR+ D GPKTI+QI ++A +++ I SD GP PP Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359 Score = 113 bits (282), Expect = 2e-24 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%) Query: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1286 P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + + Sbjct: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589 Query: 1287 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1346 L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+ Sbjct: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649 Query: 1347 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1406 + V + EL +PL G L L L L K + + L++++ ++ ++ Sbjct: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704 Query: 1407 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1465 LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+ Sbjct: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755 Query: 1466 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1510 N+S + V V LMT+ S+ + L + +L + + Sbjct: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815 Query: 1511 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1569 +QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+ Sbjct: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874 Query: 1570 AEQQGKGVALKSVTAFFKWLREAEEE 1595 E GKG AL V + WL AEEE Sbjct: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 100 bits (249), Expect = 1e-20 Identities = 113/461 (24%), Positives = 169/461 (36%), Gaps = 58/461 (12%) Query: 11 PPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAA 70 PP+P P P PP +AP T + PSQ PS PP A +Q+ Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP----PSMTTPPMQAPPSLQTIP 387 Query: 71 PAR-------PGPAAHVYPAGSQVMMIPSQISYPASQGAYYI----PGQGRSTYVVPTQQ 119 P + P A P + + + P Q + P Q +++ P++ Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447 Query: 120 YPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKT 179 P +P P + A P Q T ++PA ++ P I P + + Sbjct: 448 ASTPPDSP-------PLQAPLSLPASPPLQ------TSLSPAVSPLSSPLTIHPLQALSS 494 Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239 + P ++ IM T S+ PP +TP ++ P + Sbjct: 495 LASHSPQA---PLSSLIMPPLETQSSLAPPSL----------QTPPASLTTPPLENLPSL 541 Query: 240 IIADRPGLPGPEHSPSESQPSSPSPTP---SPSPVLEPGSEPNLAVLSIPGDTMTTIQMS 296 P +P P P+P P PSP+ P E ++ + P + Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA-- 599 Query: 297 VEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV 356 S P+ P P P A P L + + P P + SPL P+P A + + Sbjct: 600 ---SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656 Query: 357 EIH---EPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 413 +H P PS ++ SP A PP PS +P AP + L PSPPA Sbjct: 657 AVHLLQAPFSPPPSPPVQAPF--SPP-ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713 Query: 414 D-LSPVSEPEEQAKEVTAS--MAPPTIPSATPATAPSATSP 451 +SP + P QA A+ + P P A+P +PSAT P Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754 Score = 88.2 bits (217), Expect = 6e-17 Identities = 117/490 (23%), Positives = 172/490 (35%), Gaps = 71/490 (14%) Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71 P+ GL +PA ++ S+P + + PR +PS+ +P A R P Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287 Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131 R A + P S + PS P+ A +P + +P P +P P Sbjct: 288 PRKDAAPALGPLSSSPLATPS----PSGTKARPVPPPDNAATPLPA----TLPPSP---P 336 Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAP--APVLMNQPPQIAPKRERKTIRIRDPNQGG 189 A+P + + P+ P P AP M PP AP +++ P Q Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP----SLQTIPPIQVP 392 Query: 190 KDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVA-----VIVRPDDRSQGAIIADR 244 +T + P P L+ + +P + + + P R Sbjct: 393 HSLTSPSLQA------PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446 Query: 245 PGLPGPEHSPSE---SQPSSPSPTPSPSPVLEPGSEP----NLAVLSIPGDTMTTIQMSV 297 P P+ P + S P+SP S SP + P S P L LS +S Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506 Query: 298 EESTPISRETG-EPYRLSPEPTPLAEPILEVEVTL--------SKPVPESEFSSSPLQAP 348 P+ ++ P L P L P LE +L S P+ + P AP Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566 Query: 349 TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA----CPSESPVPIAPTAQPEEL- 403 PL + + P PS P ++ P LA PP P SP+ P P L Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626 Query: 404 ---LNGAPSPPAVD-LSPVSEPEEQAKE------------------VTASMAPPTIPSAT 441 L PSPPA LSP++ P QA V A +PP P + Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686 Query: 442 PATAPSATSP 451 P+ P + +P Sbjct: 687 PSATPPSQAP 696 Score = 68.9 bits (167), Expect = 4e-11 Identities = 130/539 (24%), Positives = 174/539 (32%), Gaps = 62/539 (11%) Query: 4 APQSTGPPPA-----PSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQP 58 AP S PPA P LP A PP QTA +TP + TP P P Q Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH---LETPPCPA----PCPLQA 571 Query: 59 PSSAASRVQSAAP---ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVV 115 P S + P A P P A A + +PS P S A P + Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP---PLSPLATPPPQAPPXLALP 628 Query: 116 PTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKR 175 P Q P P +P P A+P+ A A + + Q P P+P + Q P P Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVH----LLQAPFSPPPSPPV--QAPFSPPAS 682 Query: 176 ERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVR---- 231 + P+Q + + S P P P P A ++ Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740 Query: 232 -PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTM 290 P P +P +P P SP + SP+ +P + A+ + P + Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800 Query: 291 TTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP-- 348 + S P S P P P A P+L + VP S +S LQAP Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRR 857 Query: 349 TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 405 P + P + P P S L+ P S + T+ PEE L Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LR 912 Query: 406 GAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEEM 457 G S P SP + E A A P P A P P AT P + + Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972 Query: 458 EEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 516 E E E+ + G P P A A + PK+ R Sbjct: 973 CTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 1021 Score = 67.0 bits (162), Expect = 1e-10 Identities = 110/476 (23%), Positives = 171/476 (35%), Gaps = 45/476 (9%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQM--------NTPSQPRQHFYPS 54 KA + P A +PGL P PPG P TP A ++ P R Sbjct: 9 KAGAAARTPAARAPGLLTPR-PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67 Query: 55 RAQPPSSA-ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGR-ST 112 P S+ A +SA + PA+ +G P++ + P G PG+ +T Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSPGRASGTT 124 Query: 113 YVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP---- 168 P Q ++ A TE + A+ PT P+P + + Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 169 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP---PQTGGGLEPQANGETPQ 225 ++ R + R R P +G + + T +P P GGGL+ A+ Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244 Query: 226 VAVIVRPDDRS----QGAIIAD-RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL 280 A + RS +G A P P P+ + P P +P L P S L Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304 Query: 281 AVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEF 340 A S G + +TP+ P L P P PLA P+ L+ P P + Sbjct: 305 ATPSPSGTKARPVPPPDNAATPL------PATLPPSP-PLATPL-----PLAPPSPSAPP 352 Query: 341 SSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES----PVPIAP 396 S L P+P A+ + P+ P P +++ P + P + S S P P+A Sbjct: 353 SLQTL--PSPPATPPSQA-PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409 Query: 397 TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 452 ++ G+P+ A P + +T+ P + P +P + PA Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465 Score = 40.0 bits (92), Expect = 0.018 Identities = 76/347 (21%), Positives = 116/347 (33%), Gaps = 53/347 (15%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 +AP S P SP A PP Q P + + P + P+ P PS PP + Sbjct: 674 QAPFSPPASPPVSPS----ATPPSQAPPSLAAPPLQVPPSPPASPPMS--PSATPPPQAP 727 Query: 63 ASRVQSAAPARPGPAAH--VYPAGSQVMMIPSQISYPASQGAYYIPGQ-GRSTYVVPTQQ 119 P P A + P+ + +P ++ P Q P S P Q Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787 Query: 120 YP---------VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAP--APVLMNQP 168 P P P +PG +P + P+ + P P AP ++ P Sbjct: 788 APPALATPPLQALPSPPASFPGQAP---------FSPSASLPMSPLATPPPQAPPVLAAP 838 Query: 169 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGAR--TASTPTPPQ----------TGGGLE 216 P + ++ P + + +SG R A P PP +G L Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898 Query: 217 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLE--P 274 ++ T + D +G A P P+ + P++ S P+P P Sbjct: 899 GHSSSATSTPEELRGYDSGPEGGAAAS----PPPDAELAACHPAAWSRGPAPPLAFRGAP 954 Query: 275 GSEPNLAVLSIPG--DTMTTIQMSVEESTPISRETGEPYRLSPEPTP 319 G+ + PG D + TI E+ T P L P P+P Sbjct: 955 GAPLPWPPATGPGSADGLCTIY----ETEGPESATPAPGALDPGPSP 997 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 93.6 bits (231), Expect = 1e-18 Identities = 142/585 (24%), Positives = 196/585 (33%), Gaps = 111/585 (18%) Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAAS 64 P + P AP P P P G A T TP P+ A PP A Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL----ATPPPKGAP 1149 Query: 65 RVQSAAPARP-GPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQ 123 +A P P G A P G+ + P+ +G P S PT Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLATP----SPKGAPTTPAATP 1202 Query: 124 PGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIR 183 P G SP +G P P+P P +PK T Sbjct: 1203 PSPKGGLATPSP-------------KGAPTTPAATPPSPKGGLATP--SPKGAPTTPAAT 1247 Query: 184 DPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 243 P+ G T GA T TPP GGL + P AV+ P + Sbjct: 1248 PPSPKGGPATPP-PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG------- 1299 Query: 244 RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPI 303 GP SP + P+ P+ TP PSP PG+ P + P T Sbjct: 1300 -----GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVT-------------- 1339 Query: 304 SRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNG 363 P+P P L SK P + S + PTP A+ P Sbjct: 1340 ------------PPSPKGTPTLPATTPSSKGGPTTPSSK---EGPTPPAATPSHKGGP-A 1383 Query: 364 MVPSEDLEPEVESSPELAPPPACP-SESPVPIAPTAQPEELL--NGAPSPPAVDLSPVSE 420 M P P + P + P P S + +P++P P + GA +P DL+P + Sbjct: 1384 MTP-----PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438 Query: 421 PEEQAKEVTASMAP---PTIPSAT-PATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAES 476 K+ A+ AP P PS+ T P+ T P+ +E ++ +A + Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498 Query: 477 EKGGEEL---LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA 533 G L +P +PA S + A T +S ++ L KEA+ Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS----KKTPATLAPKEAL------ 1548 Query: 534 FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKE 578 PPA + P P+ + P P+EA T SKE Sbjct: 1549 -------------IPPAMTVPSPKK--TPAIPTPKEAPATPSSKE 1578 Score = 91.3 bits (225), Expect = 7e-18 Identities = 140/586 (23%), Positives = 200/586 (34%), Gaps = 61/586 (10%) Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAA 63 +P G P P+ P P P +P TP A +P P A P +A Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992 Query: 64 SRVQSAAPARPGP-AAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122 PA P P A PA + S + P +GA P + P+ Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052 Query: 123 QPGAPGFYPGASPTEFG-----TYAGAYYPAQGVQQFPTG--VAPAPVLMNQPPQIAPKR 175 GAP P+ G + GA P P G P+P PP P Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112 Query: 176 ERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 235 + + P G T + TPP G P A +P+ + P Sbjct: 1113 PKG--GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170 Query: 236 SQGAIIADRPGLPGPEHSPS-ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQ 294 + A P G +PS + P++P+ TP PSP + LA S G T Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSP------KGGLATPSPKGAPTT--- 1220 Query: 295 MSVEESTPISRETG--EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQ-APTPL 351 +TP S + G P TP A P P P+ ++ P + APTP Sbjct: 1221 ---PAATPPSPKGGLATPSPKGAPTTPAATP----------PSPKGGPATPPPKGAPTPP 1267 Query: 352 ASHTVEIHEPNGMVPSEDL-EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSP 410 A+ + P + P V + P PA P P A P +P Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327 Query: 411 PAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 470 P P P A + PT+P+ TP++ T+P+ +E + G Sbjct: 1328 P-----PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382 Query: 471 AGEAESEKGGEELLPPESTPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGD 529 A S K G + P+ P PA + + + A AT V +E + GD Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT----------REGAATPSKGD 1432 Query: 530 LLD------AFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEE 569 L + K+A PA + P S+ G + + PP P+E Sbjct: 1433 LTPPAVTPVSLKKA-PATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477 Score = 80.1 bits (196), Expect = 2e-14 Identities = 153/651 (23%), Positives = 222/651 (34%), Gaps = 109/651 (16%) Query: 11 PPAPSPGLPQPAFPPGQTAPVVFSTPQATQ------MNTPSQPRQHFYPSRAQPPSSAAS 64 PP+P GL A PP + AP +TP AT + TPS P+ A PPS Sbjct: 1156 PPSPKGGL---ATPPPKGAP---TTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGG 1208 Query: 65 RVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQP 124 + P A P+ + PS P + A P P + P P Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSPKGGPATPPPKGAPTPP 1267 Query: 125 GA--PGFYPG-ASPTEFGTYAGAYY----PAQGVQQFPTGVAPAPVLMNQPPQIAPKRER 177 A P G A+P G A P G P AP P P +PK Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP---SPKGSP 1324 Query: 178 KTIRIRDPNQGGKD---ITEEIMSGARTASTPTPPQTGGGLEPQAN-GETPQVAVIVRPD 233 T P +G +T G T TP GG P + G TP A P Sbjct: 1325 GT----PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---PS 1377 Query: 234 DRSQGAIIADRP----GLPGPEHSPSESQ--PSSPSPTPSPSPVLEPGSEPNLAVLSIPG 287 + A+ P +P P+ P+ P SP P+ E + P+ L+ P Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437 Query: 288 DTMTTIQMSVEESTP-----ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 342 T +++ + S P G+P + P EP +V S ++ + Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497 Query: 343 SPLQAPT---------------------PLASHTVEIHE--PNGMVPSEDLEPEVESSPE 379 +P+ APT P+A + + P + P E L P + P Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557 Query: 380 LAPPPACPSESPVPIAPTAQPEE--------LLNGAPSPPAVDLSP-VSEPEEQAKEVTA 430 PA P+ P P+++ GAPSP + + P V+ P + Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617 Query: 431 SMAPPTIPS--ATPATAPSATSPAQEEEMEEEEEEEEGE--------AGEAGEAESEKGG 480 ++ PP+ ATPA + TSP ++ +A + K G Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677 Query: 481 EELL-------PPESTPI---PANLSQNLEAAAATQVAVSV-PKRRRKIKELNKKEAVGD 529 L PESTPI P + ++AT + P + K A Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737 Query: 530 LLDAFKEAN-PAVPEVENQPPAGSNPGPESEGS---------GVPPRPEEA 570 LL K+++ A + + P G PES+ S V P+PE A Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788 Score = 68.6 bits (166), Expect = 5e-11 Identities = 140/588 (23%), Positives = 196/588 (33%), Gaps = 83/588 (14%) Query: 10 PPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSA 69 P PSP LP PPG T V + + S P++ P+ S+ AS + Sbjct: 731 PKSVPSPSLPPAGTPPG-TKKVDGISHTSALAPVASSPKE--CPTEDSGASATASSKGTL 787 Query: 70 APARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGF 129 P+ P G V + P P +G+ G T + PV P F Sbjct: 788 TYLADSPS----PLG--VSVSPQTKRPPTKKGS-----AGPDT-PIGNLSSPVSPVEASF 835 Query: 130 YP-------GASPTEFGTYAGAYYPAQGVQQFPTGVAP-APVLMNQPPQIAPKRERKTIR 181 P G+ + T++ +G P+ V P +P + PP+ P + Sbjct: 836 LPENSLSFQGSKDSPATTHSPTPPSPKGAPT-PSAVTPLSPKGVTLPPKETP--TPSVVN 892 Query: 182 IRDPNQG-GKDITEEIMSGARTASTP-----TPPQTGGGLEPQANG-ETPQVAVIVRPDD 234 + P +G ++ + + T+S+P TP G P G TP A P Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP-- 950 Query: 235 RSQGAIIADRPGLPGPEHSPSESQPSSPSP-----TPSPSPVLEPGSEPNLAVLSIPGDT 289 P P P+ +P+ + PSP TPSP P P S G Sbjct: 951 -------KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP---PAATPPSPKGGP 1000 Query: 290 MTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT 349 T + P P SP+ +P A P + T P S SP P Sbjct: 1001 AT----PSPKGAPTPPAVTPP---SPKGSPAATPFPKGASTPPAATPPSP-KGSPAATPL 1052 Query: 350 PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPS 409 P + T P +PS P S PPA SP T P+ GAP Sbjct: 1053 PKGAPTT----PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK----GAPM 1104 Query: 410 PP-AVDLSP---VSEPEEQAKEVTASMAPP-------TIPSATPATAPSATSPAQEEEME 458 PP A SP ++ P + T + PP T P T P+AT P+ + + Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL- 1163 Query: 459 EEEEEEEGEAGEAGEAESEKGGEELLPPESTP-IPANLSQNLEAAAATQVAVSVPKRRRK 517 + A S KGG P+ P PA + + AT PK Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT----PSPKGAPT 1219 Query: 518 IKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPP 565 G L + P P P G P +G+ PP Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267 Score = 63.5 bits (153), Expect = 2e-09 Identities = 136/642 (21%), Positives = 216/642 (33%), Gaps = 123/642 (19%) Query: 21 PAFPPGQTAPVVFSTPQAT-QMNTPSQPRQHFYPSRAQPP----SSAASRVQSAAPARPG 75 P+F ++P + +P+AT + +P P+ + +S+AS +++ + A P Sbjct: 571 PSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPD 630 Query: 76 PAAHVYPAGSQVMMIPSQISYP--ASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGA 133 A P ++ P+ ++P ++ A P + T T P G P Sbjct: 631 SAG---PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN 687 Query: 134 SPTEFGTYAGAYYPAQGVQQFPTGVAP------------APVLMNQ------PPQIAPKR 175 P + GT + P +P AP + PP P Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747 Query: 176 ERK------TIRIRDPNQGGKDITEEIMSGARTASTP--------TPPQTGGGLEPQ--- 218 +K T + K+ E + TAS+ +P G + PQ Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807 Query: 219 -------ANGETPQVAVIVRPDDRSQGAIIADRP-GLPGPEHSPSESQ-PSSPSPTPSPS 269 A +TP + + P + + + + G + SP+ + P+ PSP +P+ Sbjct: 808 PPTKKGSAGPDTP-IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866 Query: 270 P-----------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 318 P L P P +V+++P + +++ +S + P + P Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926 Query: 319 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 378 P P S SP APTP A+ T + PS P + P Sbjct: 927 PKGIPA----------------SPSPKGAPTPPAA-TPPSPKGGPATPSPKWAP---TPP 966 Query: 379 ELAPP-----PACPSESPVPIAPTAQPEE--------LLNGAPSPPAVDL-----SPVSE 420 PP PA PS P P A P GAP+PPAV SP + Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026 Query: 421 PEEQAKEVTASMAPPT---IPSATP-----ATAPSATSPAQEEEMEEEEEEEEGEAGEAG 472 P + + PP+ P+ATP T P+AT P+ + + A Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG-PATPSLKGAPTPPAA 1085 Query: 473 EAESEKGGEELLPPESTPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLL 531 S KGG P+ P+ PA + + AT P K G L Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK----GGLA 1141 Query: 532 DAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRPE 568 + P P P G P +G + PP P+ Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183 Score = 61.6 bits (148), Expect = 6e-09 Identities = 110/501 (21%), Positives = 161/501 (32%), Gaps = 98/501 (19%) Query: 5 PQSTGPPPAPSPGLPQPA---FPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61 P +T P P SPG P P PP T P TP TPS PS + P+ Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP-TLPATTPSSKGGPTTPSSKEGPTP 1371 Query: 62 AASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVP-TQQY 120 A A P+ G A P+ + IPS P S IP + P T++ Sbjct: 1372 PA-----ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV--IPLSPKKAPATPVTREG 1424 Query: 121 PVQPGAPGFYPGA--------SPTEFGTYAGAYYPA-QGVQQFPTGVAPAPVLMNQPPQI 171 P P A +P G P+ +G P P+P P Q+ Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484 Query: 172 APKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVR 231 A K G + I S + TP + P A + + + Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA-TPSSRRDPIAPTATLLSKKTPATLA 1543 Query: 232 PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 291 P + A+I +P P+ +P+ P TPS P + P Sbjct: 1544 PKE----ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599 Query: 292 TIQMSVEES-----------TPISRETGEPYRLSPEPTPLAEPILE-------------- 326 I +V TP S E G P +P+ TP + P+ Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658 Query: 327 ----------------------VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGM 364 ++ L P PE S+ + APT T Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIITAPTRKGPQT--------- 1706 Query: 365 VPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQ 424 + +SP + P P+ + S P++ T P LL P D S ++ ++ Sbjct: 1707 ------KKSSATSPPICPDPSAKNGSKGPLS-TVAPAPLL-----PVQKDSSKTAKGKDA 1754 Query: 425 AKEVTASMAPPTIPSATPATA 445 + +APP ++TP TA Sbjct: 1755 SHSPKGPLAPPESKASTPLTA 1775 Score = 43.5 bits (101), Expect = 0.002 Identities = 109/467 (23%), Positives = 167/467 (35%), Gaps = 82/467 (17%) Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAAS 64 P S P AP+ L P AP P A M PS + P+ + P++ +S Sbjct: 1520 PSSRRDPIAPTATLLSKK-TPATLAPKEALIPPA--MTVPSPKKTPAIPTPKEAPATPSS 1576 Query: 65 RVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPG-------QGRSTYV--- 114 + S+ PA P+ + + ++IP ++ P+ + A P +G +T Sbjct: 1577 KEASSPPAVT-PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635 Query: 115 VPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQG----VQQFPTG-----VAPAPV-- 163 PT PV P + P SP GA P ++ PT VAPAP Sbjct: 1636 TPTSP-PVTPSSLKDSP-TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693 Query: 164 -LMNQPPQIAPKRERKTIR----IRDPN--QGGKDITEEIMSGARTASTPTPPQTGGGLE 216 ++ P + P+ ++ + DP+ G K + +T G + Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753 Query: 217 PQANGETPQVAVIVRPDDRSQGAIIAD--RPGLPGPEH-------SPSESQPSSPSPTPS 267 + + P + P+ ++ + A LP PE SP S P +PSP P+ Sbjct: 1754 ASHSPKGP----LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809 Query: 268 PSPVLE-PGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 326 P + S P L VL P + +E P+ + PEP P Sbjct: 1810 LPPKQQFLPSSPGL-VLESPSKPLA--PADEDELLPL---------IPPEPISGGVPFQS 1857 Query: 327 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 386 V V + P S+ + PTP A V + S+ ES PEL Sbjct: 1858 VLVNMPTP------KSAGIPVPTPSAKQPVTKNNKGSGTESD----SDESVPEL------ 1901 Query: 387 PSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 433 E T Q +L A +D PVS+ ++ E A A Sbjct: 1902 --EEQDSTQATTQQAQLAAAA----EIDEEPVSKAKQSRSEKKARKA 1942 Score = 40.0 bits (92), Expect = 0.018 Identities = 110/520 (21%), Positives = 180/520 (34%), Gaps = 103/520 (19%) Query: 6 QSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASR 65 ++T PA LPQP +TA + P ++ ++ + Q P PP + + Sbjct: 4 EATETVPATEQELPQPQ---AETAVL----PMSSALSVTAALGQ---PGPTLPPPCSPAP 53 Query: 66 VQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIP---GQGRSTYVVPTQQYPV 122 Q P A +P+ S + P ++ +P S +P T++ P+ Sbjct: 54 QQ--CPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI 111 Query: 123 QPGAPGFY-PGASPTEFGTYAGAYYPAQGVQQFPTGVAPA----PVLMNQPPQIAPKRER 177 P A P +PT GT + + P V P V + P L+ PP +A Sbjct: 112 SPAALALASPMIAPTLKGTPSSSA-PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170 Query: 178 KTIRIR------DPNQGGKDITEEIMSGARTASTPTPP-----------------QTGGG 214 I + +P + E++ + TP+PP Q+G Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVPNPK--GTPSPPCIVSTVPYHCVTPMASIQSGVA 228 Query: 215 LEPQANGETPQVAVIVRPDDRSQGAIIAD--RPG---LPGPEHSPS-------------E 256 PQ T + D + +++ PG L GP P+ Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288 Query: 257 SQPSSPSPTPSPSPV-----LEPGSEPNLAVLSIPGDT-------MTTIQMSVEEST--- 301 SQ ++ TP P+ L P + + + + G T T +SV+ S+ Sbjct: 289 SQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348 Query: 302 --PISRETGEPYRLSPEPTPL---AEPILEVEVTLSKPVPES-------------EFSSS 343 P R P E P A P++ V S FS S Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408 Query: 344 PLQAPTPLASHTVEIHEP---NGMVPSEDLEPEVESSP-ELAPPPACPSESPVPIAPTAQ 399 P + +S H P V S P V ++P +A P E ++P Sbjct: 409 PTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS 468 Query: 400 PEELLNGAP-SPPAVDLSPVSEPEEQAKEVTASMAPPTIP 438 + N P SP A+ ++PV+ P+E + +V ++ P P Sbjct: 469 SGPISNIEPTSPAALVMAPVA-PKEPSTQVATTLRIPVSP 507 Score = 38.9 bits (89), Expect = 0.040 Identities = 79/336 (23%), Positives = 117/336 (34%), Gaps = 53/336 (15%) Query: 250 PEHSPS-ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR--- 305 P++SPS +S SSP SP L S + P +MT+ + V S + + Sbjct: 567 PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS-PLGVNSSASVIKTDS 625 Query: 306 ----ETGEPYRLSP--EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH 359 ++ P S PT A P+ + P S+ A +P TV + Sbjct: 626 YAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA-SPFLEGTVSLA 684 Query: 360 EPNGMVPSEDLE--PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSP 417 N V L P V ++ E P P + P+A E+ PSP L P Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP---SLPP 741 Query: 418 VSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESE 477 P K+V S T A AP A+SP +E E+ G + A S Sbjct: 742 AGTP-PGTKKVDGI-------SHTSALAPVASSP------KECPTEDSGASATA----SS 783 Query: 478 KGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR---KIKELNKKEAVGDLLDAF 534 KG L +P+ ++S P+ +R K +G+L Sbjct: 784 KGTLTYLADSPSPLGVSVS---------------PQTKRPPTKKGSAGPDTPIGNLSSPV 828 Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEA 570 + + GS P + S PP P+ A Sbjct: 829 SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 85.1 bits (209), Expect = 5e-16 Identities = 133/582 (22%), Positives = 202/582 (34%), Gaps = 100/582 (17%) Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71 P+ GL +PA ++ S+P + + PR +PS+ +P A R P Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287 Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131 R A + P S + PS + SQ +P S+ + P+ P P Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS--P 345 Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD 191 A P+ +Q P+ PP P + T + P Sbjct: 346 SAPPS--------------LQTLPS-----------PPATPP--SQATTSLGSPT---LQ 375 Query: 192 ITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPE 251 T + + TPP PQA P +A+ P L P Sbjct: 376 ATHSFLPSPPLSPLATPP-------PQA---PPALAL----------------PPLQAPP 409 Query: 252 HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 311 SP S P SP TPSP A S P S S P+S P Sbjct: 410 -SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP- 467 Query: 312 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 371 S P LA P L+V + P S ++ P QAP PLA+ +++ +P P Sbjct: 468 --SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525 Query: 372 PEVESSPELAPPPACPSESP------VPIAPTAQP---------EELLNGAPSPPAVDL- 415 P +++ P +PP + P ++P +P++P A P LL PSPPA Sbjct: 526 PPLQALP--SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583 Query: 416 -------SPVSEPEEQAKEVTASMA--PPTIPSATPATAPSATSPAQEEEMEEEEEEEEG 466 +P + +T ++A PP PS +P++ S A EE Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE-- 641 Query: 467 EAGEAGEAESEKGGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELN 522 G +GG PP + PA S+ A + A P Sbjct: 642 ---LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698 Query: 523 KKEAVGDLLDAF--KEANPAVPEVENQPPAGSNPGPESEGSG 562 + + + + + A PA ++ P G++ G + G+G Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 740 Score = 60.1 bits (144), Expect = 2e-08 Identities = 133/519 (25%), Positives = 175/519 (33%), Gaps = 90/519 (17%) Query: 4 APQSTGPPPA----PSPGLPQPAFPPGQTAPVVFS-TPQATQMNTPSQPRQHF-YPSRAQ 57 AP S PP+ PSP PA PP Q + S T QAT PS P P Sbjct: 341 APPSPSAPPSLQTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396 Query: 58 PPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPT 117 PP+ A +Q AP P + + P + P+ ++ Q + P P Sbjct: 397 PPALALPPLQ--APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-------PP 447 Query: 118 QQYPVQPGA-PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRE 176 Q P P A P P A+P + A P Q V P P PPQ P Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLA 506 Query: 177 RKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRS 236 +++ P PPQ L TP + + P Sbjct: 507 APPLQLAKP----------------------PPQAPPAL------ATPPLQALPSPP--- 535 Query: 237 QGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMS 296 A PG SPS S P SP TP P VL+ P + Sbjct: 536 -----ASFPG--QAPFSPSASLPMSPLATPPPQAP---------PVLAAP-------LLQ 572 Query: 297 VEESTPISRETGEPYRLSPEPTP---LAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 353 V S P S P R P P P ++ P L + + P P S SS L P LA Sbjct: 573 VPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-DLAG 630 Query: 354 HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL--NGAPSPP 411 H+ + D P E +PPP + P A + P L GAP P Sbjct: 631 HSSSATSTPEELRGYDSGP--EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688 Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEA 471 + P + P A + SATP AP A P + AG + Sbjct: 689 -LPWPPATGP-GSADGLCTIYETEGPESATP--APGALDPGPSPGTSGGKAAAGAGAGAS 744 Query: 472 GEA--ESEKGGEELLPPESTPIPANLSQNLEAAAATQVA 508 + ++ G L +++ + LS+ L AAA A Sbjct: 745 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 783 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 84.0 bits (206), Expect = 1e-15 Identities = 177/796 (22%), Positives = 269/796 (33%), Gaps = 141/796 (17%) Query: 9 GPPPAPSPG----LPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA-- 62 G PPA PG P PA PP Q P + P A Q T P Q P +PP+ Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPGTVKPPVQP--PGTTKPPAQPLG 367 Query: 63 -----ASRVQSAAPA--RPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---------P 106 A + S P+ +PGP A P G V P+Q PA + P Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425 Query: 107 GQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMN 166 G + PVQ PG P T A P + Q P P P Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP---- 481 Query: 167 QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226 Q P A ++ + P+Q + ST PPQ G +P +PQ Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQ-------------QPGSTKPPPQQPGPAKP-----SPQQ 523 Query: 227 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIP 286 +P + +PG P S + P+ PS S PV + GS Sbjct: 524 PGSTKPPSQ--------QPGSAKP--SAQQPSPAKPSAQQSTKPVSQTGS---------- 563 Query: 287 GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT--LSKPVPESEFSSSP 344 P+ T P P L + I + T L VPE ++ Sbjct: 564 -------------GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610 Query: 345 LQAPTPLAS--------HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES--PVPI 394 + T + S H E+ E + + + + +LAP P+ P P+ Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCL----NCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 395 APTA-------QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM--APPTIPSATPATA 445 T+ QP++ + P DLS EP++ V P+ + P A Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726 Query: 446 PSATSPAQEEEMEEEEEEEEGEAGEAGEAESE--KGGEELLPPESTPIPANLSQNLEAAA 503 S + PA +E E+++ + + + K +L+ S ++ + + Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786 Query: 504 ATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGV 563 A + + P + K G+ + F + A+P + S+PGP SE G Sbjct: 787 AEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASDSKIISHPGPSSESKG- 842 Query: 564 PPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFI 623 + D + E + + K K D KP+ G Q + Sbjct: 843 -----------QKQVDPVQKKEEPKKAQTKMSPKPDA-KPMPKGSPTPPGPRPTAG-QTV 889 Query: 624 FASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGP--DFTPSFANLGRTTLSTR 681 Q P+ L+ + T PT Q G F S + +ST Sbjct: 890 PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA 949 Query: 682 GPP----RGGPGGELPRGPAGLGPRRSQQGPR---KEPRKIIATVLMTEDIKLNKAEK-- 732 G P + GPG + + PA P SQ P+ + P ++ + ++ K AEK Sbjct: 950 GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE 1009 Query: 733 ---AWKPSSKRTAADK 745 P+ KRT +K Sbjct: 1010 PKAEQAPTVKRTETEK 1025 Score = 65.5 bits (158), Expect = 4e-10 Identities = 129/619 (20%), Positives = 208/619 (33%), Gaps = 109/619 (17%) Query: 5 PQSTGP--PPAPSPGLPQP-AFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61 PQ GP PP PG +P + PG T P PQ PS + +Q P S Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKP----PPQQPGPAKPSPQQPGSTKPPSQQPGS 536 Query: 62 AASRVQSAAPARPGPAAHVYP---AGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVP-- 116 A Q +PA+P P GS + P +S A Q P QG + P Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP----PSQGLPKTICPLC 592 Query: 117 ------------------TQQYPVQPGAPGFYPGASPTEFGTYA---GAYYPAQGVQQFP 155 T+ GF P TE + A G P Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652 Query: 156 TGVAPAPVLMN--------------QPPQIAPKRE----RKTIRIRDPNQGGKDITEEIM 197 +P P L QP Q +PK++ + + +P + + + + Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712 Query: 198 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 257 G+ +A PP+ L A + P V P ++ + + D+P P P+ Sbjct: 713 HGSPSAKAKQPPE-ADSLSKPAPPKEPSV-----PSEQDKAPVADDKPKQP-KMVKPTTD 765 Query: 258 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST--PISRETGEPYRLSP 315 SS S T P IP + +Q EE T P+ ++ +P + P Sbjct: 766 LVSSSSATTKP---------------DIPS---SKVQSQAEEKTTPPLKTDSAKPSQSFP 807 Query: 316 EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 375 P E + + SK +P S + P P + E + P + E + Sbjct: 808 ---PTGEKVSPFD---SKAIPRPASDSKIISHPGP----SSESKGQKQVDPVQKKEEPKK 857 Query: 376 SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP 435 + +++P P P+P P + P SP +P+EQ++ + ++ Sbjct: 858 AQTKMSPK---PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP--KPQEQSRRFSLNLGSI 912 Query: 436 TIPSATPATAPSATSPAQ----EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 491 T + T P T + + + AG+ G G P + P Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG---APMKQAPA 969 Query: 492 PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAG 551 P+ + +T A P + +K+ K A + L+ E P V E + Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPA-AEKLEPKAEQAPTVKRTETE---- 1024 Query: 552 SNPGPESEGSGVPPRPEEA 570 P P + + P++A Sbjct: 1025 KKPPPIKDSKSLTAEPQKA 1043 Score = 63.9 bits (154), Expect = 1e-09 Identities = 98/404 (24%), Positives = 148/404 (36%), Gaps = 88/404 (21%) Query: 149 QGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP 208 Q Q P G+ P L QPP+ PK++ RDP Q +D T + +S + + Sbjct: 197 QKEQGKPEGIIKPP-LQQQPPKPIPKQQGPG---RDPLQ--QDGTPKSISSQQPEKIKSQ 250 Query: 209 PQTGGGLEPQANGETPQVAVIVRPDDRS-------QGAIIAD---RPGLPGPEHSPSESQ 258 P G G Q +TPQ P R Q I+ +P LP P S+ Sbjct: 251 PP-GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP------SK 303 Query: 259 PSSPSPTPSPSPVLEPG---SEPNLA------------VLSIPGDTMTTIQ--------- 294 P PTP P +PG S+P A + PG +Q Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 295 MSVEESTPISRETG--EPYRLSPEPTPLAEP---------------ILEVEVTLSKPVPE 337 + + P +++TG +P P P LA+P +V KP+ + Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 338 SEFSSSPLQAPTPLASHTVEIHEPN-GMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 396 SP +AP P + + +P G +P++ P S+ + P PS+ P P P Sbjct: 424 QPGLQSPAKAPGPTKT---PVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPAKP 479 Query: 397 ------TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP---TIPSATPATA-P 446 A+P G+ PP+ P +Q S P PS P +A P Sbjct: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539 Query: 447 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 490 SA P+ + ++ + + G G+ L PP +P Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTG---------SGKPLQPPTVSP 574 Score = 61.6 bits (148), Expect = 6e-09 Identities = 132/615 (21%), Positives = 206/615 (33%), Gaps = 97/615 (15%) Query: 6 QSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASR 65 Q TGP PS LP PA PP Q PQ QP PS Q P S Sbjct: 462 QQTGPTKPPSQ-LPGPAKPPPQQPGPAKPPPQ--------QPGSAKPPS--QQPGSTKPP 510 Query: 66 VQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPG 125 Q PA+P P P P+ Q PG + P+ Q P P Sbjct: 511 PQQPGPAKPSPQQ------------PGSTKPPSQQ-----PGSAK-----PSAQQP-SPA 547 Query: 126 APGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 185 P P + G+ P Q P+ A P P I P + + P Sbjct: 548 KPSAQQSTKPV---SQTGSGKPLQPPTVSPS--AKQPPSQGLPKTICPLCNTTELLLHVP 602 Query: 186 NQGGKDITEEIMSG--ARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 243 + + E + + P P T E + + R+ G +A Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLT----------EVKEWLCLNCQMKRALGGDLAP 652 Query: 244 RPGLPGPE------HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV 297 P P P+ + S SSP P + SP + + +L+ P ++ Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQT-SPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711 Query: 298 EESTPISRETGEPYRLS-PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV 356 +P ++ P S +P P EP + E + + ++ T L S + Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771 Query: 357 EIHEPNGMVPSEDLEPEVE--SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVD 414 +P+ +PS ++ + E ++P L A PS+S P P + + A PA D Sbjct: 772 ATTKPD--IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASD 827 Query: 415 LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQE-EEMEEEEEEEEGEAGEAGE 473 +S P ++ P P A + SP + + M + G AG+ Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887 Query: 474 AESEKGGEELLPPESTPIPANLSQ--NLEAAAATQVAVSVPKRRRK-------------I 518 + P+ +P P S+ +L + T S P ++ Sbjct: 888 T--------VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939 Query: 519 KELNKKEAVGDLLDAFKEANPAVP----EVENQPPAGSNPGPESEGSGVPPRPEEADETW 574 + + + ++ P P +QPP P P+S G PP P ++ Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP-PKSTGQ-APPAPAKSIPV- 996 Query: 575 DSKEDKIHNAENIQP 589 KE K AE ++P Sbjct: 997 -KKETKAPAAEKLEP 1010 Score = 58.2 bits (139), Expect = 6e-08 Identities = 142/692 (20%), Positives = 239/692 (34%), Gaps = 132/692 (19%) Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 ++KAP+ PPP + QP G + P+A ++ P+ P++ PS Sbjct: 694 LSKAPEPKKPPPL----VKQPTLH-GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748 Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120 A + + +P + + IPS S SQ ++ P+Q + Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSF 806 Query: 121 P-----VQPGAPGFYP-GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPP----- 169 P V P P AS ++ ++ G ++G +Q PV + P Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD------PVQKKEEPKKAQT 860 Query: 170 QIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLE------------- 216 +++PK + K + P G T + PTP Q+ E Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPT-------AGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913 Query: 217 --PQANGETPQVAVIVR-----PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269 P++ TPQ V + SQ + + G PGP P +P PS Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973 Query: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329 P + P + + +S P+ +ET P EP P ++ Sbjct: 974 PTSQG-----------PPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022 Query: 330 TLSKPVP---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 386 T KP P ++ P +A P E + +L + P C Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082 Query: 387 PSE-------SPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPS 439 ++ +P P Q E L + A+ Q ++ P+ P Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQ-EWLCLNCQTQRAI--------SGQLGDIRKMPPAPSGPK 1133 Query: 440 ATPATAPSATS------PAQEEEMEEEEEEEEGEAGEA-GEAESEKGGEELLPPESTPIP 492 A+P P+ +S P Q + ++++E+E + EA + E E E +PP T Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193 Query: 493 ANLSQNLE--AAAATQVAVSVPKRRRKIKELNK--KEAVGDLLDAFK---EANPAVPEVE 545 LE A+A Q +P+ ++ I E K E LL+ K E +PE + Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253 Query: 546 NQPP-----------------------------AGSNPGPESEG--SGVPPR-PEEADET 573 P G P + EG SG P P+E D+T Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKT 1313 Query: 574 WDSKEDK-----IHNAENIQPGEQKYEYKSDQ 600 + +++ + ++PG++K E + D+ Sbjct: 1314 TKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDK 1345 Score = 42.0 bits (97), Expect = 0.005 Identities = 60/236 (25%), Positives = 85/236 (36%), Gaps = 40/236 (16%) Query: 231 RPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP-----SPSPVLEPGSEPNLAVLSI 285 RP RS I+ +P P P P P P P P SP P + P + L V S Sbjct: 2391 RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILP--KKKLTVAS- 2447 Query: 286 PGDTMTTI--QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSS 343 P T T + ++ E+T + R G P+ + T PVP Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNG-------------LPVTRICTTAPPPVPPK----- 2489 Query: 344 PLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE-E 402 P+ + S V H P P +P + P P P ++ T+ Sbjct: 2490 ----PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLN 2545 Query: 403 LLNGA----PSPPAVDLSPVSEPEEQ--AKEVTASMAPPTIPSATPATAPSATSPA 452 L+ A PSP + LSP S +K +T + T+PS S+ S A Sbjct: 2546 LVTSADYKLPSPTS-PLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQA 2600 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 84.0 bits (206), Expect = 1e-15 Identities = 177/796 (22%), Positives = 269/796 (33%), Gaps = 141/796 (17%) Query: 9 GPPPAPSPG----LPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA-- 62 G PPA PG P PA PP Q P + P A Q T P Q P +PP+ Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPGTVKPPVQP--PGTTKPPAQPLG 367 Query: 63 -----ASRVQSAAPA--RPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---------P 106 A + S P+ +PGP A P G V P+Q PA + P Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425 Query: 107 GQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMN 166 G + PVQ PG P T A P + Q P P P Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP---- 481 Query: 167 QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226 Q P A ++ + P+Q + ST PPQ G +P +PQ Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQ-------------QPGSTKPPPQQPGPAKP-----SPQQ 523 Query: 227 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIP 286 +P + +PG P S + P+ PS S PV + GS Sbjct: 524 PGSTKPPSQ--------QPGSAKP--SAQQPSPAKPSAQQSTKPVSQTGS---------- 563 Query: 287 GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT--LSKPVPESEFSSSP 344 P+ T P P L + I + T L VPE ++ Sbjct: 564 -------------GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610 Query: 345 LQAPTPLAS--------HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES--PVPI 394 + T + S H E+ E + + + + +LAP P+ P P+ Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCL----NCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 395 APTA-------QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM--APPTIPSATPATA 445 T+ QP++ + P DLS EP++ V P+ + P A Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726 Query: 446 PSATSPAQEEEMEEEEEEEEGEAGEAGEAESE--KGGEELLPPESTPIPANLSQNLEAAA 503 S + PA +E E+++ + + + K +L+ S ++ + + Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786 Query: 504 ATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGV 563 A + + P + K G+ + F + A+P + S+PGP SE G Sbjct: 787 AEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASDSKIISHPGPSSESKG- 842 Query: 564 PPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFI 623 + D + E + + K K D KP+ G Q + Sbjct: 843 -----------QKQVDPVQKKEEPKKAQTKMSPKPDA-KPMPKGSPTPPGPRPTAG-QTV 889 Query: 624 FASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGP--DFTPSFANLGRTTLSTR 681 Q P+ L+ + T PT Q G F S + +ST Sbjct: 890 PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA 949 Query: 682 GPP----RGGPGGELPRGPAGLGPRRSQQGPR---KEPRKIIATVLMTEDIKLNKAEK-- 732 G P + GPG + + PA P SQ P+ + P ++ + ++ K AEK Sbjct: 950 GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE 1009 Query: 733 ---AWKPSSKRTAADK 745 P+ KRT +K Sbjct: 1010 PKAEQAPTVKRTETEK 1025 Score = 65.5 bits (158), Expect = 4e-10 Identities = 129/619 (20%), Positives = 208/619 (33%), Gaps = 109/619 (17%) Query: 5 PQSTGP--PPAPSPGLPQP-AFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61 PQ GP PP PG +P + PG T P PQ PS + +Q P S Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKP----PPQQPGPAKPSPQQPGSTKPPSQQPGS 536 Query: 62 AASRVQSAAPARPGPAAHVYP---AGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVP-- 116 A Q +PA+P P GS + P +S A Q P QG + P Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP----PSQGLPKTICPLC 592 Query: 117 ------------------TQQYPVQPGAPGFYPGASPTEFGTYA---GAYYPAQGVQQFP 155 T+ GF P TE + A G P Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652 Query: 156 TGVAPAPVLMN--------------QPPQIAPKRE----RKTIRIRDPNQGGKDITEEIM 197 +P P L QP Q +PK++ + + +P + + + + Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712 Query: 198 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 257 G+ +A PP+ L A + P V P ++ + + D+P P P+ Sbjct: 713 HGSPSAKAKQPPE-ADSLSKPAPPKEPSV-----PSEQDKAPVADDKPKQP-KMVKPTTD 765 Query: 258 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST--PISRETGEPYRLSP 315 SS S T P IP + +Q EE T P+ ++ +P + P Sbjct: 766 LVSSSSATTKP---------------DIPS---SKVQSQAEEKTTPPLKTDSAKPSQSFP 807 Query: 316 EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 375 P E + + SK +P S + P P + E + P + E + Sbjct: 808 ---PTGEKVSPFD---SKAIPRPASDSKIISHPGP----SSESKGQKQVDPVQKKEEPKK 857 Query: 376 SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP 435 + +++P P P+P P + P SP +P+EQ++ + ++ Sbjct: 858 AQTKMSPK---PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP--KPQEQSRRFSLNLGSI 912 Query: 436 TIPSATPATAPSATSPAQ----EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 491 T + T P T + + + AG+ G G P + P Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG---APMKQAPA 969 Query: 492 PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAG 551 P+ + +T A P + +K+ K A + L+ E P V E + Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPA-AEKLEPKAEQAPTVKRTETE---- 1024 Query: 552 SNPGPESEGSGVPPRPEEA 570 P P + + P++A Sbjct: 1025 KKPPPIKDSKSLTAEPQKA 1043 Score = 63.9 bits (154), Expect = 1e-09 Identities = 98/404 (24%), Positives = 148/404 (36%), Gaps = 88/404 (21%) Query: 149 QGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP 208 Q Q P G+ P L QPP+ PK++ RDP Q +D T + +S + + Sbjct: 197 QKEQGKPEGIIKPP-LQQQPPKPIPKQQGPG---RDPLQ--QDGTPKSISSQQPEKIKSQ 250 Query: 209 PQTGGGLEPQANGETPQVAVIVRPDDRS-------QGAIIAD---RPGLPGPEHSPSESQ 258 P G G Q +TPQ P R Q I+ +P LP P S+ Sbjct: 251 PP-GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP------SK 303 Query: 259 PSSPSPTPSPSPVLEPG---SEPNLA------------VLSIPGDTMTTIQ--------- 294 P PTP P +PG S+P A + PG +Q Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 295 MSVEESTPISRETG--EPYRLSPEPTPLAEP---------------ILEVEVTLSKPVPE 337 + + P +++TG +P P P LA+P +V KP+ + Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 338 SEFSSSPLQAPTPLASHTVEIHEPN-GMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 396 SP +AP P + + +P G +P++ P S+ + P PS+ P P P Sbjct: 424 QPGLQSPAKAPGPTKT---PVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPAKP 479 Query: 397 ------TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP---TIPSATPATA-P 446 A+P G+ PP+ P +Q S P PS P +A P Sbjct: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539 Query: 447 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 490 SA P+ + ++ + + G G+ L PP +P Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTG---------SGKPLQPPTVSP 574 Score = 61.6 bits (148), Expect = 6e-09 Identities = 132/615 (21%), Positives = 206/615 (33%), Gaps = 97/615 (15%) Query: 6 QSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASR 65 Q TGP PS LP PA PP Q PQ QP PS Q P S Sbjct: 462 QQTGPTKPPSQ-LPGPAKPPPQQPGPAKPPPQ--------QPGSAKPPS--QQPGSTKPP 510 Query: 66 VQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPG 125 Q PA+P P P P+ Q PG + P+ Q P P Sbjct: 511 PQQPGPAKPSPQQ------------PGSTKPPSQQ-----PGSAK-----PSAQQP-SPA 547 Query: 126 APGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 185 P P + G+ P Q P+ A P P I P + + P Sbjct: 548 KPSAQQSTKPV---SQTGSGKPLQPPTVSPS--AKQPPSQGLPKTICPLCNTTELLLHVP 602 Query: 186 NQGGKDITEEIMSG--ARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 243 + + E + + P P T E + + R+ G +A Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLT----------EVKEWLCLNCQMKRALGGDLAP 652 Query: 244 RPGLPGPE------HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV 297 P P P+ + S SSP P + SP + + +L+ P ++ Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQT-SPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711 Query: 298 EESTPISRETGEPYRLS-PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV 356 +P ++ P S +P P EP + E + + ++ T L S + Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771 Query: 357 EIHEPNGMVPSEDLEPEVE--SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVD 414 +P+ +PS ++ + E ++P L A PS+S P P + + A PA D Sbjct: 772 ATTKPD--IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASD 827 Query: 415 LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQE-EEMEEEEEEEEGEAGEAGE 473 +S P ++ P P A + SP + + M + G AG+ Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887 Query: 474 AESEKGGEELLPPESTPIPANLSQ--NLEAAAATQVAVSVPKRRRK-------------I 518 + P+ +P P S+ +L + T S P ++ Sbjct: 888 T--------VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939 Query: 519 KELNKKEAVGDLLDAFKEANPAVP----EVENQPPAGSNPGPESEGSGVPPRPEEADETW 574 + + + ++ P P +QPP P P+S G PP P ++ Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP-PKSTGQ-APPAPAKSIPV- 996 Query: 575 DSKEDKIHNAENIQP 589 KE K AE ++P Sbjct: 997 -KKETKAPAAEKLEP 1010 Score = 58.2 bits (139), Expect = 6e-08 Identities = 142/692 (20%), Positives = 239/692 (34%), Gaps = 132/692 (19%) Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 ++KAP+ PPP + QP G + P+A ++ P+ P++ PS Sbjct: 694 LSKAPEPKKPPPL----VKQPTLH-GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748 Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120 A + + +P + + IPS S SQ ++ P+Q + Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSF 806 Query: 121 P-----VQPGAPGFYP-GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPP----- 169 P V P P AS ++ ++ G ++G +Q PV + P Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD------PVQKKEEPKKAQT 860 Query: 170 QIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLE------------- 216 +++PK + K + P G T + PTP Q+ E Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPT-------AGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913 Query: 217 --PQANGETPQVAVIVR-----PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269 P++ TPQ V + SQ + + G PGP P +P PS Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973 Query: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329 P + P + + +S P+ +ET P EP P ++ Sbjct: 974 PTSQG-----------PPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022 Query: 330 TLSKPVP---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 386 T KP P ++ P +A P E + +L + P C Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082 Query: 387 PSE-------SPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPS 439 ++ +P P Q E L + A+ Q ++ P+ P Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQ-EWLCLNCQTQRAI--------SGQLGDIRKMPPAPSGPK 1133 Query: 440 ATPATAPSATS------PAQEEEMEEEEEEEEGEAGEA-GEAESEKGGEELLPPESTPIP 492 A+P P+ +S P Q + ++++E+E + EA + E E E +PP T Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193 Query: 493 ANLSQNLE--AAAATQVAVSVPKRRRKIKELNK--KEAVGDLLDAFK---EANPAVPEVE 545 LE A+A Q +P+ ++ I E K E LL+ K E +PE + Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253 Query: 546 NQPP-----------------------------AGSNPGPESEG--SGVPPR-PEEADET 573 P G P + EG SG P P+E D+T Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKT 1313 Query: 574 WDSKEDK-----IHNAENIQPGEQKYEYKSDQ 600 + +++ + ++PG++K E + D+ Sbjct: 1314 TKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDK 1345 Score = 42.0 bits (97), Expect = 0.005 Identities = 60/236 (25%), Positives = 85/236 (36%), Gaps = 40/236 (16%) Query: 231 RPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP-----SPSPVLEPGSEPNLAVLSI 285 RP RS I+ +P P P P P P P P SP P + P + L V S Sbjct: 2391 RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILP--KKKLTVAS- 2447 Query: 286 PGDTMTTI--QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSS 343 P T T + ++ E+T + R G P+ + T PVP Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNG-------------LPVTRICTTAPPPVPPK----- 2489 Query: 344 PLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE-E 402 P+ + S V H P P +P + P P P ++ T+ Sbjct: 2490 ----PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLN 2545 Query: 403 LLNGA----PSPPAVDLSPVSEPEEQ--AKEVTASMAPPTIPSATPATAPSATSPA 452 L+ A PSP + LSP S +K +T + T+PS S+ S A Sbjct: 2546 LVTSADYKLPSPTS-PLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQA 2600 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 83.6 bits (205), Expect = 1e-15 Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59 KA +T P +P P P +TP+ TP +P P+ + P Sbjct: 200 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 247 Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118 + ++ P P P PA + P+ PA P +S P + Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 300 Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178 P P P P T P + PT PAP +P APK+ Sbjct: 301 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358 Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238 T P + +E +PT P+ P P P Sbjct: 359 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 411 Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298 P P P+ + P P+PT P EP P T T Sbjct: 412 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 463 Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 P EP +P+ T P T K P + +P P LA T E Sbjct: 464 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 520 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418 EP P E P P A +P APT P+E P PA Sbjct: 521 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 564 Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478 + P+E A AP T+ P T PA +E +E + + K Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621 Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534 G P E P PA + A + ++ KEL G Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681 Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573 + P P+ E P P P + P PE T Sbjct: 682 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 719 Score = 81.3 bits (199), Expect = 7e-15 Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 K+ +T PAP+ P P + AP P T TP +P P+ + P+ Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 289 Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122 ++ P P P PA P+ PA +T PT P Sbjct: 290 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 331 Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179 +P P + + PA + P T PAP +P PK T Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391 Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239 P + S T P+P T P P + A Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451 Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293 + P P+ + P P+PT P+ L P + LA + TT Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 510 Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351 EE P + E EP +PE P T +P P + +P + P P Sbjct: 511 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565 Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411 P G P+ EP + + AP P+ + P + T P+P Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 618 Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469 + + P+E A AP T P T P+ T+P + E +G Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678 Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524 + + +E P P T E T VS P ++ ++K Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 738 Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580 E+ +L A P +EN P PG + + +PE D ++ Sbjct: 739 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 788 Score = 58.9 bits (141), Expect = 4e-08 Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%) Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261 TP PP + G GL+ NG+ + PD + +H+ + P Sbjct: 79 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 118 Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320 + P +P P L P S+ + S+ + TT++ +E+T +++T + E T Sbjct: 119 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 172 Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369 A+ +E T L+KP P++E ++ TP EP P E Sbjct: 173 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 232 Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415 ++S+P PA + P P T +P P+P P Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292 Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468 S + P+E A AP PT P T P +P +E +E A Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352 Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519 + + K P E P P + +A T P + Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412 Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577 K+ + KE P P+ E P P P + P P+E T K Sbjct: 413 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 83.6 bits (205), Expect = 1e-15 Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59 KA +T P +P P P +TP+ TP +P P+ + P Sbjct: 241 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 288 Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118 + ++ P P P PA + P+ PA P +S P + Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 341 Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178 P P P P T P + PT PAP +P APK+ Sbjct: 342 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399 Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238 T P + +E +PT P+ P P P Sbjct: 400 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 452 Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298 P P P+ + P P+PT P EP P T T Sbjct: 453 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 504 Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 P EP +P+ T P T K P + +P P LA T E Sbjct: 505 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 561 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418 EP P E P P A +P APT P+E P PA Sbjct: 562 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 605 Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478 + P+E A AP T+ P T PA +E +E + + K Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662 Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534 G P E P PA + A + ++ KEL G Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722 Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573 + P P+ E P P P + P PE T Sbjct: 723 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 760 Score = 81.3 bits (199), Expect = 7e-15 Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 K+ +T PAP+ P P + AP P T TP +P P+ + P+ Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 330 Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122 ++ P P P PA P+ PA +T PT P Sbjct: 331 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 372 Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179 +P P + + PA + P T PAP +P PK T Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432 Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239 P + S T P+P T P P + A Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492 Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293 + P P+ + P P+PT P+ L P + LA + TT Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 551 Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351 EE P + E EP +PE P T +P P + +P + P P Sbjct: 552 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606 Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411 P G P+ EP + + AP P+ + P + T P+P Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 659 Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469 + + P+E A AP T P T P+ T+P + E +G Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719 Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524 + + +E P P T E T VS P ++ ++K Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 779 Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580 E+ +L A P +EN P PG + + +PE D ++ Sbjct: 780 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 829 Score = 58.9 bits (141), Expect = 4e-08 Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%) Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261 TP PP + G GL+ NG+ + PD + +H+ + P Sbjct: 120 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 159 Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320 + P +P P L P S+ + S+ + TT++ +E+T +++T + E T Sbjct: 160 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 213 Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369 A+ +E T L+KP P++E ++ TP EP P E Sbjct: 214 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 273 Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415 ++S+P PA + P P T +P P+P P Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333 Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468 S + P+E A AP PT P T P +P +E +E A Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393 Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519 + + K P E P P + +A T P + Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453 Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577 K+ + KE P P+ E P P P + P P+E T K Sbjct: 454 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 83.6 bits (205), Expect = 1e-15 Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59 KA +T P +P P P +TP+ TP +P P+ + P Sbjct: 293 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 340 Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118 + ++ P P P PA + P+ PA P +S P + Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 393 Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178 P P P P T P + PT PAP +P APK+ Sbjct: 394 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451 Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238 T P + +E +PT P+ P P P Sbjct: 452 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 504 Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298 P P P+ + P P+PT P EP P T T Sbjct: 505 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 556 Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 P EP +P+ T P T K P + +P P LA T E Sbjct: 557 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 613 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418 EP P E P P A +P APT P+E P PA Sbjct: 614 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 657 Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478 + P+E A AP T+ P T PA +E +E + + K Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714 Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534 G P E P PA + A + ++ KEL G Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774 Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573 + P P+ E P P P + P PE T Sbjct: 775 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 812 Score = 81.3 bits (199), Expect = 7e-15 Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 K+ +T PAP+ P P + AP P T TP +P P+ + P+ Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 382 Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122 ++ P P P PA P+ PA +T PT P Sbjct: 383 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 424 Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179 +P P + + PA + P T PAP +P PK T Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 484 Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239 P + S T P+P T P P + A Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544 Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293 + P P+ + P P+PT P+ L P + LA + TT Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 603 Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351 EE P + E EP +PE P T +P P + +P + P P Sbjct: 604 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658 Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411 P G P+ EP + + AP P+ + P + T P+P Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 711 Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469 + + P+E A AP T P T P+ T+P + E +G Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 771 Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524 + + +E P P T E T VS P ++ ++K Sbjct: 772 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 831 Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580 E+ +L A P +EN P PG + + +PE D ++ Sbjct: 832 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 881 Score = 58.9 bits (141), Expect = 4e-08 Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%) Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261 TP PP + G GL+ NG+ + PD + +H+ + P Sbjct: 172 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 211 Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320 + P +P P L P S+ + S+ + TT++ +E+T +++T + E T Sbjct: 212 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 265 Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369 A+ +E T L+KP P++E ++ TP EP P E Sbjct: 266 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 325 Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415 ++S+P PA + P P T +P P+P P Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385 Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468 S + P+E A AP PT P T P +P +E +E A Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445 Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519 + + K P E P P + +A T P + Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505 Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577 K+ + KE P P+ E P P P + P P+E T K Sbjct: 506 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 83.6 bits (205), Expect = 1e-15 Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59 KA +T P +P P P +TP+ TP +P P+ + P Sbjct: 334 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 381 Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118 + ++ P P P PA + P+ PA P +S P + Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 434 Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178 P P P P T P + PT PAP +P APK+ Sbjct: 435 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492 Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238 T P + +E +PT P+ P P P Sbjct: 493 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 545 Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298 P P P+ + P P+PT P EP P T T Sbjct: 546 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 597 Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 P EP +P+ T P T K P + +P P LA T E Sbjct: 598 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 654 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418 EP P E P P A +P APT P+E P PA Sbjct: 655 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 698 Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478 + P+E A AP T+ P T PA +E +E + + K Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755 Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534 G P E P PA + A + ++ KEL G Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815 Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573 + P P+ E P P P + P PE T Sbjct: 816 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 853 Score = 81.3 bits (199), Expect = 7e-15 Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 K+ +T PAP+ P P + AP P T TP +P P+ + P+ Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 423 Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122 ++ P P P PA P+ PA +T PT P Sbjct: 424 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 465 Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179 +P P + + PA + P T PAP +P PK T Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 525 Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239 P + S T P+P T P P + A Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585 Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293 + P P+ + P P+PT P+ L P + LA + TT Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 644 Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351 EE P + E EP +PE P T +P P + +P + P P Sbjct: 645 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699 Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411 P G P+ EP + + AP P+ + P + T P+P Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 752 Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469 + + P+E A AP T P T P+ T+P + E +G Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 812 Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524 + + +E P P T E T VS P ++ ++K Sbjct: 813 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 872 Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580 E+ +L A P +EN P PG + + +PE D ++ Sbjct: 873 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 922 Score = 58.9 bits (141), Expect = 4e-08 Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%) Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261 TP PP + G GL+ NG+ + PD + +H+ + P Sbjct: 213 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 252 Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320 + P +P P L P S+ + S+ + TT++ +E+T +++T + E T Sbjct: 253 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 306 Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369 A+ +E T L+KP P++E ++ TP EP P E Sbjct: 307 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 366 Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415 ++S+P PA + P P T +P P+P P Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426 Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468 S + P+E A AP PT P T P +P +E +E A Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486 Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519 + + K P E P P + +A T P + Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546 Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577 K+ + KE P P+ E P P P + P P+E T K Sbjct: 547 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 83.2 bits (204), Expect = 2e-15 Identities = 130/519 (25%), Positives = 192/519 (36%), Gaps = 69/519 (13%) Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60 + ++P S PSP L P PP + +P+ +P + +P P P+ P + Sbjct: 515 LEESPLSPPEESPPSPALETPLSPPPEASPL---SPPFEE--SPLSPPPEELPTSPPPEA 569 Query: 61 SAASRVQSAAPARPGP----------AAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGR 110 S S +P P P A+ ++P + + P P S P Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS------PPPEA 623 Query: 111 STYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQ 170 S P + P+ P P P + P E + P V + +P ++ PP+ Sbjct: 624 SRLSPPPEDSPMSP-PPEESPMSPPPEVSRLS----PLPVVSRLSPPPEESP--LSPPPE 676 Query: 171 IAPKRER-KTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVI 229 +P + R+ P E+ + +P P L E+P + + Sbjct: 677 ESPTSPPPEASRLSPP-------PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729 Query: 230 VRPD--DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPG 287 P RS+G ++ RP P P E S + P SP E EP L ++P Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE---EPCLC--AVPE 784 Query: 288 DTMTTIQMSVEESTP------ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFS 341 + + Q +P +S +T EP+ LSP P EP L + S P+SE Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTEEPH-LSPVPE---EPCLSPQPEESHLSPQSE-- 838 Query: 342 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES---SPE---LAPPPACPSESPVPIA 395 P +P P SH E + P + PE +PE L PPP PS SP+ Sbjct: 839 -EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897 Query: 396 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEE 455 P +P P + LSP EP + + PP + A AP A SP E Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957 Query: 456 EMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPAN 494 E G G++ + ES L P S P AN Sbjct: 958 EY------PFGAKGDS-DPESPLAAPILETPISPPPEAN 989 Score = 75.5 bits (184), Expect = 4e-13 Identities = 104/403 (25%), Positives = 146/403 (36%), Gaps = 69/403 (17%) Query: 187 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 246 QGG+ I S +PP+ G + P + G + + +P Sbjct: 353 QGGQTIRSVAEQHTPVCSRFSPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPK 407 Query: 247 LPGP---EHSPS-----ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298 PGP E P + +P +P P+L P P + LS P Sbjct: 408 EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP---PEESPLSPP-----------P 453 Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--PLASHTV 356 E +P S E RLSP P L L + LS+P+ ES S P ++P P S Sbjct: 454 EESPTSPPP-EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512 Query: 357 EIHEPNGMVPSEDLEPEVESSPELAPPP-ACPSESPVPIAPTAQPEELLNGAPSPPAVDL 415 E + + P E+ P L+PPP A P P +P + P E L +P P A L Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572 Query: 416 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATS----PAQEEEMEEEEEEEEGEAGEA 471 SP PEE + M+PP P +P + P S P +E + EE Sbjct: 573 SP--PPEE------SPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622 Query: 472 GEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLL 531 S PPE +P+ + + +S P ++ L V L Sbjct: 623 ASRLSP-------PPEDSPM---------SPPPEESPMSPPPEVSRLSPL----PVVSRL 662 Query: 532 DAFKEANPAVPEVENQP----PAGSNPGPESEGSGVPPRPEEA 570 E +P P E P P S P E S P PE++ Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705 Score = 69.7 bits (169), Expect = 2e-11 Identities = 100/392 (25%), Positives = 139/392 (35%), Gaps = 44/392 (11%) Query: 205 TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS----PSESQPS 260 T P+ G L+ +A P V+ + + + + + P LP PE S P E P+ Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT 458 Query: 261 SPSPTP---SPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVE-------ESTPISRETGE 309 SP P SP P P S P LS P + E ES+P S Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518 Query: 310 PYRLSPEPTPLAEPILEVEVT-------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPN 362 P LSP P LE ++ LS P ES S P + PT + P Sbjct: 519 P--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576 Query: 363 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-- 420 P + P E SP PP A P +P + P E +P P A LSP E Sbjct: 577 EESP---MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633 Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE--MEEEEEEEEGEAGEAGEAESEK 478 P E + PP + +P S SP EE EE EA Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP-- 691 Query: 479 GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 538 PPE +P + + +S+P + L ++ + + + Sbjct: 692 ------PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLS 744 Query: 539 PAVPEVENQP-PAGSNPGPESEGSGVPPRPEE 569 P E P P + P++E + P+PEE Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776 Score = 68.2 bits (165), Expect = 6e-11 Identities = 132/549 (24%), Positives = 194/549 (35%), Gaps = 98/549 (17%) Query: 10 PPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSA 69 PPP SP P P P T+P P+A++++ P + P+ P + SR Sbjct: 442 PPPEESPLSPPPEESP--TSP----PPEASRLSPPPEE----LPASPLPEALHLSRPLEE 491 Query: 70 APARPGP----------AAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQ 119 +P P P ++ P + P + + P S P ++ Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551 Query: 120 YPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIA------- 172 P+ P P P + P E A P ++ P P M+ PP+ + Sbjct: 552 SPLSP-PPEELPTSPPPE----ASRLSPPP--EESPMSPPPEESPMSPPPEASRLFPPFE 604 Query: 173 ------PKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226 P E + ++ + MS S +PP L P P V Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP-----LPVV 659 Query: 227 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQP--SSPSPTPSPSPVLEPGSE------P 278 + + P + S P P PE SP+ P S SP P SP P + P Sbjct: 660 SRLSPPPEES--------PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711 Query: 279 NLAVLSIPGDTMTTIQMSVE-------ESTPISRETGEPYRLSPEPTPLAEPILEVEVTL 331 +++S+P + + + E E +S EP+ LSP P EP L + Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH-LSPRP---EEPHLSPQAEE 767 Query: 332 SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED---LEPEVESSPELAPPPACPS 388 P+ E P P H E + P + L P+ E P L+P P P Sbjct: 768 PHLSPQPE---EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE-EPHLSPVPEEPC 823 Query: 389 ESPVPIAPTAQPE-ELLNGAPSPPAVDLSPVSE-------PEEQAKEVTASMAPPTIPSA 440 SP P P+ E +P P LSP E PE+ +E AP +P Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883 Query: 441 TPATAPSATSPAQEEEMEEEEE------EEEGEAGEAGEAESEKGGEELLPPESTPIPAN 494 P PS + E + E E EE +GE +L+PP+ P+P Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL---SPQLMPPD--PLPPP 938 Query: 495 LSQNLEAAA 503 LS + AAA Sbjct: 939 LSPIITAAA 947 Score = 57.8 bits (138), Expect = 8e-08 Identities = 128/512 (25%), Positives = 170/512 (33%), Gaps = 124/512 (24%) Query: 121 PVQPGAPGFYP-GASPTEF----GTYAGAYYPAQGVQQFPTGVAPAP-----VLMNQPPQ 170 P QPGA G P A+PT F T AG A G + P G P P + + PPQ Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166 Query: 171 IAPKRERKTIRIRDP-NQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVI 229 + + + +DP E A P P TG +P P + Sbjct: 2167 VPAQ-----VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP------PMLGAS 2215 Query: 230 VRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS-PVLEPGSEPNLAVLSIPGD 288 RP G PG P QPS+P P P P L+ NLAV PG Sbjct: 2216 SRPGAGQPGEFHTTPPGTP-------RHQPSTPDPFLKPRCPSLD-----NLAVPESPGV 2263 Query: 289 TMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV---EVTLSKP---VPESEFSS 342 + EP LSP P + LEV E+ S P P F Sbjct: 2264 G--------------GGKASEPL-LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVD 2308 Query: 343 SP----------LQAP-------TPLASHTVEIHEPN-GMVPSED-----LEPEVESSPE 379 SP L+ P TP AS VE P G+ P E L P S P+ Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQ-VEPQSPGLGLRPQEPPPAQALAPSPPSHPD 2367 Query: 380 L----------APPPACPSESPVP------IAPTAQPEELLNGAPSPP---AVDLSPVSE 420 + A PP P P P + P + P + + P+ P + SP++ Sbjct: 2368 IFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP 2427 Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQE------EEMEEEEEEEEGEAGEAGEA 474 A+ S P S P + P + +++ + + E +AG Sbjct: 2428 RPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHT 2487 Query: 475 ESEKGGEELLPPES------TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG 528 GG P +P+ N + T V P R +AVG Sbjct: 2488 SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR----FTFPQAVG 2543 Query: 529 DLLDAFKEANPAVPEVENQPPAGSN----PGP 556 + P VP+ PP G N PGP Sbjct: 2544 E-----PSLKPPVPQPGLPPPHGINSHFGPGP 2570 Score = 52.8 bits (125), Expect = 3e-06 Identities = 121/550 (22%), Positives = 184/550 (33%), Gaps = 105/550 (19%) Query: 4 APQSTGPPPAP-------SPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQ-----PR--- 48 +PQ+ GP +P SP +P P P + P+ + ++ S+ PR Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848 Query: 49 QHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIP--SQISYPASQGAYYIP 106 H P +PP S P PG PA ++ + P + S G + Sbjct: 849 SHLSPELEKPPLSPRPE---KPPEEPGQC----PAPEELPLFPPPGEPSLSPLLGEPALS 901 Query: 107 GQGRSTYVVPTQQYPVQP-GAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLM 165 G ++ P+ P G P P P + P ++P + Sbjct: 902 EPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD---------------PLPPPLSPI-ITA 945 Query: 166 NQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQ 225 PP ++P E + P D E A TP P P+AN P+ Sbjct: 946 AAPPALSPLGE-----LEYPFGAKGDSDPESPLAAPILETPISPP------PEANCTDPE 994 Query: 226 VA--VIVRPDDRS-----QGAIIADRPGLPGP--EHS--PSESQPSSPSPTPSPSPVLEP 274 +I+ P S ++ P P +HS P S PS SP P V P Sbjct: 995 PVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054 Query: 275 GSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKP 334 S P V+ + D +M E+ + EP SP P+P+ + + P Sbjct: 1055 LS-PIGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGD----LSCPAPSP 1108 Query: 335 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI 394 P + S + PL +P L E++ SP L P +P+ + Sbjct: 1109 APALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEV 1168 Query: 395 APTA------------QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM----APPTIP 438 P Q E AP+PP + S + + AS + P + Sbjct: 1169 YPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLG 1228 Query: 439 SATPATAPSAT---------SPAQEE-----------EMEEEEEEEEGEAGEAGEAESEK 478 S P S + SPA++E E ++ + G A G+AE EK Sbjct: 1229 SPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEK 1288 Query: 479 GGEELLPPES 488 G P S Sbjct: 1289 GRRRSSPARS 1298 Score = 52.0 bits (123), Expect = 5e-06 Identities = 72/336 (21%), Positives = 115/336 (34%), Gaps = 49/336 (14%) Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPV-----LMNQPPQIAPKRERKTIRIRDPN 186 G +P T G P+ V P P L QPP P ++++ + + Sbjct: 4052 GTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTA 4111 Query: 187 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 246 GG ++ SG+ + ++ P P V++ +P +Q + +P Sbjct: 4112 GGGSH--GQLGSGSSSEASSVPHLLA----------QPSVSLGDQPGSMTQNLLGPQQPM 4159 Query: 247 LPGPEHSPSESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISR 305 L P + + QP P P PVL+ G P + ++ G +Q + ++ + Sbjct: 4160 LERPMQNNTGPQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR- 4212 Query: 306 ETGEPYRLSPEPTPLAEPIL-------EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 LSP+ + +L V + P E +SPLQ Sbjct: 4213 ------HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266 Query: 359 HEP-NGMVPSEDLEPEVESSPELAPPPACPSESPV--PIAPTAQPEELLNGAPSPPAVDL 415 P G + P + P L PP S PV P+ PT PS P Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP--------PPSSPQEPK 4318 Query: 416 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 451 P P ++ T + PPT P P+ P Sbjct: 4319 RPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354 Score = 40.8 bits (94), Expect = 0.011 Identities = 90/382 (23%), Positives = 127/382 (33%), Gaps = 77/382 (20%) Query: 147 PAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTP 206 P Q+ GV P+ L P A R+ + +RD T E+ S A+ P Sbjct: 4631 PPSVQQKMVNGVTPSEELGEHPKDAASARDSERA-LRD--------TSEVKSLDLLAALP 4681 Query: 207 TPPQTGGG---LEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 263 TPP +E + ++P V P + + + P P E + + S Sbjct: 4682 TPPHNQTEDVRMESDEDSDSPDSIV---PASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738 Query: 264 PT----PSPSPVLEPGSEPNLAV-LSIPGDTMTTIQ---MSVEESTPISRETGEPYRLSP 315 P P S + P ++P A+ L +PG T E S ++ L+ Sbjct: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNG 4798 Query: 316 EPTPLAEPILEVEVTLSKPVPESE---FSSSPLQAPTPLASHTVE--------------I 358 +AE LS +P S F SP +A T E Sbjct: 4799 VMVAVAE-------LLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPD 4851 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ------------------P 400 P+ + + + P +L ESP P PT P Sbjct: 4852 TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPP 4911 Query: 401 EELLNGAPSPPAVDL--SPVSEPEEQAKEV-TASMAPPTIPSATPATAPSATSPAQEEEM 457 EE PSPP L SP S P E E+ T +A P +PS P A+SP Sbjct: 4912 EE-----PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP----LASSPESARPK 4962 Query: 458 EEEEEEEEGEAGEAGEAESEKG 479 EEGE + KG Sbjct: 4963 PRARPPEEGEDSRPPRLKKWKG 4984 Score = 39.7 bits (91), Expect = 0.024 Identities = 161/747 (21%), Positives = 244/747 (32%), Gaps = 189/747 (25%) Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPR----QHFYPS------ 54 P+ PPP LP + P + V S + +P PR + F PS Sbjct: 2385 PRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444 Query: 55 -----RAQPPSSAASRVQSA---APARPGPAAHVYPAGSQV----------MMIPS---- 92 ++PPS SR A P RP P + AGS +P+ Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504 Query: 93 --QISYPASQGAYYIPGQGRSTYV---------------VPTQQYPV-QPGAP------- 127 P+ Q ++ G +V P+ + PV QPG P Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS 2564 Query: 128 ---------------------GFYPGASPTEFGTYAGAYYPAQGVQQF-PTGVAPAPVLM 165 F+P SP G +G+ + G+ P V P P Sbjct: 2565 HFGPGPTLGKPQSTNYTVATGNFHPSGSP--LGPSSGSTGESYGLSPLRPPSVLPPPAPD 2622 Query: 166 NQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGG------LEPQA 219 P ++ +++ I P + +D + S TA P G LE Q Sbjct: 2623 GSLPYLSHGASQRS-GITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681 Query: 220 NGETPQVAV----IVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS------------ 263 + + + I R R + A G GP S ++PSSP+ Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWG-AEPSSPAFEQLSRGQTPFA 2740 Query: 264 ------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 311 P+ P+L PGS P+ LS P T M V S + + Y Sbjct: 2741 GTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDV-NSRQLVGGSQAFY 2799 Query: 312 RLSPEPTPL--------------AEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTV 356 + +P P L A + +S P + QA +PLA + Sbjct: 2800 QRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIST 2859 Query: 357 EIHEPNGMV-----PSEDLEPEVESSPELAP---------PPACP-----SESPVPIAPT 397 + P V P++ +E L P PP P SE P +AP Sbjct: 2860 RLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPE 2919 Query: 398 AQPEELLNGAP-----SPPAVDLSPVSEPEEQAKEVTASMAPPTI---PSAT------PA 443 ++G P +PPA +L+ P K T + PS+T P Sbjct: 2920 GLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPL 2979 Query: 444 TAPSATSPAQEEEMEEE-------EEEEE----GEAGEAGEAESEKGGEELLPPESTPIP 492 + P ++ E++++ E++EE G + + + E G E L + Sbjct: 2980 ALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLD 3039 Query: 493 ANLS-QNLEAAAATQVAVSVPKRR-------RKIKELNKKEAVGDLLDAFKEANPAVPEV 544 L+ + A T + ++ R ++ N+K LL E P PE Sbjct: 3040 DLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGV-EPGPLGPE- 3097 Query: 545 ENQPPA--GSNPGPESEGSGVPPRPEE 569 E PPA S P S V P+ EE Sbjct: 3098 ERPPPAADASEPRLASVLPEVKPKVEE 3124 Score = 38.1 bits (87), Expect = 0.069 Identities = 91/396 (22%), Positives = 128/396 (32%), Gaps = 48/396 (12%) Query: 198 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD-DRSQGAIIADRPGLPGPEHSPSE 256 SG T STPT P T G + +G + + R + D G + P L + P+ Sbjct: 1976 SGGTTPSTPTTPTTEG----EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031 Query: 257 SQ--PSSPS------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST- 301 Q P S P +P L+ + A Q++ + Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG 2091 Query: 302 PISRETGEP---YRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 I+R+T P R+ P+P L P T+ F SP S + Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTI--------FIGSPTTPAGLSTSADGFL 2143 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418 P G VP D E+ P PS+ P +AP E AP SP Sbjct: 2144 KPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT 2203 Query: 419 SEPEEQAKEVTASMAP--------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 470 P Q + AS P T P TP PS P + + E+ Sbjct: 2204 GAP-AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262 Query: 471 AGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDL 530 G K E LL +P P S+ ++ S P + G Sbjct: 2263 VG---GGKASEPLL----SPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTH 2315 Query: 531 LDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPR 566 L + P V + P A S P+S G G+ P+ Sbjct: 2316 LGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQ 2350 Score = 38.1 bits (87), Expect = 0.069 Identities = 92/473 (19%), Positives = 158/473 (33%), Gaps = 58/473 (12%) Query: 9 GPPPAPSPGLPQP--AFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRV 66 GP P P LP P A G V TP + P +P Q PS PSS Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQ--LPS----PSSQLPTE 4333 Query: 67 QSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQ-PG 125 P PG P G + P ++S A+Q A + +G + P Q P Sbjct: 4334 AQLPPTHPGTPK---PQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390 Query: 126 APGFYPGASPTEFGTY---AGAYYPAQGVQQFPTGVAPAPVL--MNQPPQIAPKRERKTI 180 PG G A Q ++ P + V N P AP + Sbjct: 4391 QSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL 4450 Query: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240 ++ G + ++++ A+ T + GL + NG D + Sbjct: 4451 LAGPRSEAGHLLLQKLLR-AKNVQLST-GRGSEGLRAEINGHI----------DSKLAGL 4498 Query: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300 G P + + +P +P P + D + + + + + Sbjct: 4499 EQKLQGTPSNKEDAAARKPLTPKPKR----------------VQKASDRLVSSRKKLRKE 4542 Query: 301 TPISRETGEPYRLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358 + +L E + PL EP + +L P S P+ + L Sbjct: 4543 DGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFG----SGCPVNGQSQLRGAFGSG 4598 Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418 P G D ++ + L+ PP PS P P P + ++++NG P+ +L Sbjct: 4599 ALPTG----PDYYSQLLTKNNLSNPPTPPSSLP-PTPPPSVQQKMVNGV--TPSEELGEH 4651 Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEA 471 + A++ ++ + + A T P + E E +E+ ++ ++ Sbjct: 4652 PKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDS 4704 Score = 35.8 bits (81), Expect = 0.34 Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 57/215 (26%) Query: 246 GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 305 G PGP+ P + + P P P PG+ VL Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--------------------- 4303 Query: 306 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 365 P +P P+ EP P Q P+P + E P Sbjct: 4304 ----PVHPTPPPSSPQEP------------------KRPSQLPSPSSQLPTEAQLP---- 4337 Query: 366 PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 425 P+ P+ + P L PPP S + +A T + L P P +L+ +PE+ Sbjct: 4338 PTHPGTPKPQ-GPTLEPPPGRVSPAAAQLADTLFSKGL---GPWDPPDNLAETQKPEQ-- 4391 Query: 426 KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEE 460 +S+ P + P A+ + ++E EE Sbjct: 4392 ----SSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422 Score = 32.0 bits (71), Expect = 4.9 Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 19/76 (25%) Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPP-SSA 62 AP P P PSP P PA PP T P+V P++P A+PP S Sbjct: 4908 APPPEEPSPPPSPLAPSPASPP--TEPLV---------ELPTEP-------LAEPPVPSP 4949 Query: 63 ASRVQSAAPARPGPAA 78 S ARP P A Sbjct: 4950 LPLASSPESARPKPRA 4965 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 82.0 bits (201), Expect = 4e-15 Identities = 129/513 (25%), Positives = 168/513 (32%), Gaps = 78/513 (15%) Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAAS 64 P PP APSP P PPG P V S P A M PS PS A Sbjct: 648 PAPVPPPEAPSPFRAPPFHPPGPM-PSVGSMPSAGPM-----------PSAGPMPS--AG 693 Query: 65 RVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQP 124 V SA P P A H+ + +P +S P + P Sbjct: 694 PVPSARPGPPTTANHLG------LSVPGLVSVPPR----------------------LLP 725 Query: 125 GAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRD 184 G G++ +G P + G P P ++ + A E I + Sbjct: 726 GPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVE---ISLES 782 Query: 185 PNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADR 244 + I E + P PP +G P A P + V + + + Sbjct: 783 DSDDSVVIVPEGLP-----PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPE-----EL 832 Query: 245 PGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV---EEST 301 P PGP P P P P P P L P P + +T I ++ EE Sbjct: 833 PAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEE 892 Query: 302 PISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI--H 359 E E E E E E + E EF + L E Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952 Query: 360 EPNGMVPSEDLE-----PEVESSPELAPPPACPSESPVPIAPT-AQPEELLNGAPSPPAV 413 E + EDLE EVE PPP P P P +P QPE P P Sbjct: 953 EEEELEEVEDLEFGTAGGEVEEGAP--PPPTLPPALPPPESPPKVQPE------PEPEPG 1004 Query: 414 DLSPVSEP---EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 470 L V EP EE+ + ++AP +PS SPA +E EEE Sbjct: 1005 LLLEVEEPGTEEERGADTAPTLAPEALPSQGEVER-EGESPAAGPPPQELVEEEPSAPPT 1063 Query: 471 AGEAESEKGGEELLPPESTPIPANLSQNLEAAA 503 E E+E G +++ PP TP + EA A Sbjct: 1064 LLEEETEDGSDKVQPPPETPAEEEMETETEAEA 1096 Score = 68.9 bits (167), Expect = 4e-11 Identities = 92/360 (25%), Positives = 129/360 (35%), Gaps = 29/360 (8%) Query: 250 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 309 P P S PS P PS P + N LS+PG ++ + + Sbjct: 678 PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737 Query: 310 PYRLSPEPTPLAEPILEVEVTLSKPVPESEF------SSSPLQAPTPLASHTVEIHEPNG 363 P L+P TP P + + T VP F +S ++ S + P G Sbjct: 738 PI-LAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794 Query: 364 MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL------LNGAPSPPAVDLSP 417 + P P + P +AP P+ SP P+ +PEEL L P PP P Sbjct: 795 LPPLPPPPPSGATPPPIAPTGP-PTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852 Query: 418 VSEPEEQA--KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 475 V+ P Q + PP + +++ +EEE EEEEEEEE E E E Sbjct: 853 VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912 Query: 476 SEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFK 535 E+ EE E + E + + +EL + E + + A Sbjct: 913 EEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL-EFGTAGG 970 Query: 536 EANPAVPEVENQPPAGSNPGPESEGSGVP-PRPE-----EADETWDSKEDKIHNAENIQP 589 E P PPA P PES P P PE E +E +E A + P Sbjct: 971 EVEEGAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028 Score = 45.8 bits (107), Expect = 3e-04 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 41/321 (12%) Query: 319 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 378 P P+ + T P P P +AP+P + H P M P V S P Sbjct: 633 PRVPPLQPMGPTCPTPAPVP-----PPEAPSPFRAPP--FHPPGPM-------PSVGSMP 678 Query: 379 ELAPPPAC---PSESPVPIAPTAQPEELLN-GAPSPPAVDLSPVSEPEEQAKEVTASMAP 434 P P+ PS PVP A P + G P V + P P + ++ P Sbjct: 679 SAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738 Query: 435 PTIPSATPATA--PSATSPAQ--EEEMEEEEEEEEGEAGEAGEAESEKGG---EELLPPE 487 PS TP P T + ++EE + + E++S+ E LPP Sbjct: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798 Query: 488 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 547 P P+ + A A + + +EL A L P VP Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL---PAAPGPLPPPPPPPPPVPGPVTL 855 Query: 548 PPAGSNPGPESEGSGVPPRPEE---------ADETWDSKEDKIHNAENIQPGEQKYEYK- 597 PP P + G G PP EE +DE + +E++ E + E+ +E + Sbjct: 856 PPPQLVP-EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914 Query: 598 --SDQWKPLNLEEKKRYDREF 616 +++ EE++ ++ EF Sbjct: 915 EDEEEYFEEEEEEEEEFEEEF 935 Score = 31.6 bits (70), Expect = 6.4 Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 3/42 (7%) Query: 848 QKEFEKDKDDDEVF---EKKQKEMDEAATAEERGRLKEELEE 886 +++FE++++D+E + E++++E E EE G L+EE EE Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 82.0 bits (201), Expect = 4e-15 Identities = 130/537 (24%), Positives = 190/537 (35%), Gaps = 85/537 (15%) Query: 10 PPPAPSPGLPQPA-FPPGQTAPVVFSTPQATQMN---------TPSQPRQHFYPSRAQPP 59 P PAP+PG A P T + F+ P T N TP P PS P Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899 Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRST---YVVP 116 + + S VQ+ P G ++P ++ P + + + G G V P Sbjct: 900 AQSVSPVQAPPP------------GGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSP 947 Query: 117 TQQYPVQPGA--PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPK 174 PVQ GA P +P T +G P P P +QP ++ Sbjct: 948 PFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLS------PATLPGPT--SQPQKVLLP 999 Query: 175 RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD- 233 + ++ + GG + + A T T + P V+P Sbjct: 1000 SSTRITYVQ--SAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLL 1057 Query: 234 DRSQGAIIADRPG------LPGPEHSPSESQPSSP--------SPTPSPS-PVLEPGSEP 278 Q ++A PG +P P+ P+ + P P SP P+ S P+ +P P Sbjct: 1058 SAGQAPLLA--PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP 1115 Query: 279 NLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPES 338 V ++ T T ++ P + T P SP P+ A +T S P++ Sbjct: 1116 PSLVYTVATST-TPPAATILPKGPPAPATATPAPTSPFPSATAG-----SMTYSLVAPKA 1169 Query: 339 EFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA 398 Q P+P A V+ + +P E P P P P E P P+ Sbjct: 1170 -------QRPSPKAPQKVKAAIAS--IPVGSFEAGASGRP--GPAPRQPLE-PGPVREPT 1217 Query: 399 QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME 458 PE L G P+PPA P PE TA +PP P A T SA P E M Sbjct: 1218 APESELEGQPTPPA----PPPLPETWTP--TARSSPPLPPPAEERT--SAKGP---ETMA 1266 Query: 459 EEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRR 515 + + G+ E GE PP P PA +++ + A P+R+ Sbjct: 1267 SKFPSSSSDWRVPGQG-LENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERK 1322 Score = 65.9 bits (159), Expect = 3e-10 Identities = 113/428 (26%), Positives = 156/428 (36%), Gaps = 57/428 (13%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 K P+S G P P + A PP ++ T + P++ Q A+ PS+ Sbjct: 601 KRPESVGGLEPPGPSVI--AAPPSGGGNIL-----QTLVLPPNKEEQE--GGGARVPSAP 651 Query: 63 ASRVQSAAPARP--GPAAH-----VYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVV 115 A + APA P PAA V P S + I S+ +P S A P Sbjct: 652 APSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASK-PFPTSGRAEASPND------- 703 Query: 116 PTQQYPVQPGAPGFYPGASPTEFGTY------AGAYYPAQGVQQFP----TGVAPAPV-- 163 T + G PG SP A A PA + P G APA V Sbjct: 704 -TAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTN 762 Query: 164 -LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGE 222 L+ P AP + GG SGA S P P G L+P A G+ Sbjct: 763 LLVGTPGYGAPAPPAVQFIAQGAPGGGTTAG----SGAGAGSGPNGPVPLGILQPGALGK 818 Query: 223 TPQVAVI--VRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL 280 + + + P Q + P P + PS P+PT S L PG+ N Sbjct: 819 AGGITQVQYILPTLPQQLQVAP----APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNG 874 Query: 281 AVLSIPGDTM-TTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESE 339 VL+ T I SV + P ++ P + +P P A+ +L +V + P Sbjct: 875 KVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQ-APPPGGSAQ-LLPGKVLVPLAAPSMS 932 Query: 340 FSSSPLQAPTPLASHTVEIHEPNGMVPSE---DLEPEVESSPELAPPPACPSESPVPIAP 396 P PL S + NG P L P S+P PP P+ P P Sbjct: 933 VRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLP---GP 989 Query: 397 TAQPEELL 404 T+QP+++L Sbjct: 990 TSQPQKVL 997 Score = 52.8 bits (125), Expect = 3e-06 Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 45/292 (15%) Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAA 63 AP G P PSP LP PG PV+ + + T S P AQP + Sbjct: 1066 APGQVGVSPVPSPQLPPACAAPG--GPVITAFYSGSPAPTSSAP-------LAQPSQAPP 1116 Query: 64 SRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY--VVPTQQYP 121 S V + A + PAA + P G + PA + G TY V P Q P Sbjct: 1117 SLVYTVATSTTPPAATILPKGPPA----PATATPAPTSPFPSATAGSMTYSLVAPKAQRP 1172 Query: 122 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTG-VAPAPVLMNQPPQIAPKRERKTI 180 P AP A A P + +G PAP QP + P RE Sbjct: 1173 -SPKAPQKVKAAI---------ASIPVGSFEAGASGRPGPAP---RQPLEPGPVREPTAP 1219 Query: 181 RIR---DPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQ 237 P E + +S P PP E + + + P+ P S Sbjct: 1220 ESELEGQPTPPAPPPLPETWTPTARSSPPLPPPA----EERTSAKGPETMASKFPSSSSD 1275 Query: 238 GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDT 289 + PG + + +P +P P+P+P+P + PG + GDT Sbjct: 1276 WRV----PG----QGLENRGEPPTP-PSPAPAPAVAPGGSSESSSGRAAGDT 1318 Score = 32.7 bits (73), Expect = 2.9 Identities = 42/178 (23%), Positives = 59/178 (33%), Gaps = 33/178 (18%) Query: 310 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369 P+ +P P +P E + S PV + Q+ P S V P G S D Sbjct: 42 PFLAPSQPDPSVQPS-EAQQPASHPVASN-------QSKEPAESAAVAHERPPGGTGSAD 93 Query: 370 LEPEVESSPELAPPPACPSESPVP------------IAPTAQPEELLNGAPSPPAVDLSP 417 E PP A ESP P P EE +G P P +D Sbjct: 94 PE---------RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLD--- 141 Query: 418 VSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 475 SE E + S+ P I P S + + + E++G + E + Sbjct: 142 -SETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKD 198 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 81.3 bits (199), Expect = 7e-15 Identities = 132/568 (23%), Positives = 202/568 (35%), Gaps = 102/568 (17%) Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71 P+ GL +PA ++ S+P + + PR +PS+ +P A R P Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278 Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131 R A + P S + PS + P+ P S +P+ P P + Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPS-------PSAPPSLQTLPSP--PATPPSQATTS 329 Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD 191 SPT T+ ++ P+ + T AP + PP AP Sbjct: 330 LGSPTLQATH--SFLPSPPLSPLATPPPQAPPALALPPLQAP------------------ 369 Query: 192 ITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLP-GP 250 P+PP +P ++ + P ++ A+ P P Sbjct: 370 --------------PSPP------------ASPPLSPLATPSPQAPNALAVHLLQAPFSP 403 Query: 251 EHSPSESQPSSPSPTPSPSPVLEPGSE--PNLAV--LSIPGDTMTTIQMSVEESTPISRE 306 SP P SP +P SP P S+ P+LA L +P + MS + P Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP---- 459 Query: 307 TGEPYRLSPEPTPLAEPILEVEVTLSKPVPES--EFSSSPLQA-PTPLASHTVEI-HEPN 362 P PLA P L+ L+KP P++ ++ PLQA P+P AS + P+ Sbjct: 460 -------PQAPPPLAAPPLQ----LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508 Query: 363 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPE 422 +P L + P APP VP +P A P P P D S VS P Sbjct: 509 ASLPMSPL----ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS-VSGP- 562 Query: 423 EQAKEVTASMA--PPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480 +T ++A PP PS +P++ S A EE G +GG Sbjct: 563 ----RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGG 613 Query: 481 EELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF-- 534 PP + PA S+ A + A P + + + + Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673 Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSG 562 + A PA ++ P G++ G + G+G Sbjct: 674 ESATPAPGALDPGPSPGTSGGKAAAGAG 701 Score = 53.1 bits (126), Expect = 2e-06 Identities = 125/532 (23%), Positives = 169/532 (31%), Gaps = 97/532 (18%) Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQ----------------- 46 A + GP + P P+ PP +AP T + PSQ Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342 Query: 47 PRQHFYPSRAQPPSSAASRVQSAAPARPGPAAH--VYPAGSQVMMIPSQISYPASQGAYY 104 P P PP + + A P P A + P + P+ ++ Q + Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402 Query: 105 IPGQGRSTYVVPTQQYPVQPGA-PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPV 163 P P Q P P A P P A+P + A P Q V P P Sbjct: 403 PPPS-------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSP 454 Query: 164 LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGET 223 PPQ P +++ P PPQ L T Sbjct: 455 SATPPPQAPPPLAAPPLQLAKP----------------------PPQAPPAL------AT 486 Query: 224 PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVL 283 P + + P A PG SPS S P SP TP P VL Sbjct: 487 PPLQALPSPP--------ASFPG--QAPFSPSASLPMSPLATPPPQAP---------PVL 527 Query: 284 SIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTP---LAEPILEVEVTLSKPVPESEF 340 + P + V S P S P R P P P ++ P L + + P P S Sbjct: 528 AAP-------LLQVPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579 Query: 341 SSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQP 400 SS L P LA H+ + D P E +PPP + P A + P Sbjct: 580 PSSTLSGP-DLAGHSSSATSTPEELRGYDSGP--EGGAAASPPPDAELAACHPAAWSRGP 636 Query: 401 EELL--NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME 458 L GAP P + P + P A + SATP AP A P Sbjct: 637 APPLAFRGAPGAP-LPWPPATGP-GSADGLCTIYETEGPESATP--APGALDPGPSPGTS 692 Query: 459 EEEEEEEGEAGEAGEA--ESEKGGEELLPPESTPIPANLSQNLEAAAATQVA 508 + AG + + ++ G L +++ + LS+ L AAA A Sbjct: 693 GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 744 >gi|33386693 poly(A) binding protein interacting protein 1 isoform 2 [Homo sapiens] Length = 400 Score = 80.9 bits (198), Expect = 9e-15 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%) Query: 701 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 760 P+++ + +P+ ++A VLM++ + +N E S + G ED L Sbjct: 26 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 79 Query: 761 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 815 V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS Sbjct: 80 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 139 Query: 816 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875 A +C L + + NFR+LLL RC+ E+E Sbjct: 140 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 172 Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 923 +K++ + ++ R+R + F+GEL+ L++ + + + + + L Sbjct: 173 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 228 Query: 924 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 980 N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288 Query: 981 DVLDLRGSNW 990 +++LR SNW Sbjct: 289 KLVELRSSNW 298 >gi|17511255 poly(A) binding protein interacting protein 1 isoform 1 [Homo sapiens] Length = 479 Score = 80.9 bits (198), Expect = 9e-15 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%) Query: 701 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 760 P+++ + +P+ ++A VLM++ + +N E S + G ED L Sbjct: 105 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 158 Query: 761 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 815 V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS Sbjct: 159 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 218 Query: 816 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875 A +C L + + NFR+LLL RC+ E+E Sbjct: 219 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 251 Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 923 +K++ + ++ R+R + F+GEL+ L++ + + + + + L Sbjct: 252 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 307 Query: 924 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 980 N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367 Query: 981 DVLDLRGSNW 990 +++LR SNW Sbjct: 368 KLVELRSSNW 377 Score = 31.6 bits (70), Expect = 6.4 Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 20/123 (16%) Query: 361 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 403 PNG P+E L+P P PPP E P P P A PE+ Sbjct: 32 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQT 91 Query: 404 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT---PATAPSATSPAQEEEMEEE 460 P + D P E + +AP + + P PS S + E E+ Sbjct: 92 RPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDG 151 Query: 461 EEE 463 E+ Sbjct: 152 CED 154 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 79.3 bits (194), Expect = 3e-14 Identities = 149/666 (22%), Positives = 225/666 (33%), Gaps = 149/666 (22%) Query: 41 MNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQ 100 + P +P + P +PP++ S AAP P PA P S Sbjct: 519 LGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG--------------LSP 564 Query: 101 GAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAP 160 G P + + P+ Y Q G P P G+A Sbjct: 565 GGSRRPPRSPERTLSPSSGYSSQSGTPTLP------------------------PKGLAG 600 Query: 161 APVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQAN 220 P P + P + + +R P G ++ + S ++S P P G PQ Sbjct: 601 PPA---SPGKAQPPKPERVTSLRSP---GASVSSSLTSLCSSSSDPAPSDRSG---PQ-- 649 Query: 221 GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLEPGS 276 ++ DR +I P +P P SP S+P SP+P +P+ V P S Sbjct: 650 -------ILTPLGDR---FVIPPHPKVPAP-FSPPPSKPRSPNPAAPALAAPAVVPGPVS 698 Query: 277 EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 336 + + S P T T ++ES IS++ P P P P P P P Sbjct: 699 TTDASPQSPP--TPQTTLTPLQESPVISKDQSPP----PSPPPSYHP----------PPP 742 Query: 337 ESEFSSSPLQAPTPLASHTVE--IHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI 394 ++ ++AP+ AS T E + +PN PPP P E + + Sbjct: 743 PTKKPEVVVEAPS--ASETAEEPLQDPNWP----------------PPPPPAPEEQDLSM 784 Query: 395 APTAQPEELLNGAPSP----PAVDLSPVSEPEEQAKEVTASM----APPTIPSATPATAP 446 A PEE SP P+ VS P + TA P P A PA AP Sbjct: 785 ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 Query: 447 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQ 506 ++++P ++ ++E + G E G L+ P + S A T Sbjct: 845 ASSAPGHVAKLPQKEPV---GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901 Query: 507 V----AVSVPKRRRKIKELNKKEAVGDLLDAFKEANP-AVPEVENQPPAGSNPGPESEGS 561 A P RR + A L A ++ E A N PE+E Sbjct: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE-- 959 Query: 562 GVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQ 621 PRP ++ + S G +K + + +P++ E + R + + Sbjct: 960 ---PRPPQSPASTAS--------FIFSKGSRKLQLE----RPVSPETQADLQRNLVAELR 1004 Query: 622 FIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTR 681 I S Q+P P K+P P R + P +PS+ T Sbjct: 1005 SI--SEQRPPQAP----------KKSPKAPPPVARKPSVGVPPPASPSYPRAEPLT---- 1048 Query: 682 GPPRGG 687 PP G Sbjct: 1049 APPTNG 1054 Score = 53.5 bits (127), Expect = 2e-06 Identities = 115/484 (23%), Positives = 162/484 (33%), Gaps = 98/484 (20%) Query: 3 KAPQSTGPPPA----PSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQP 58 K P PPP+ P+P P A P PV ST A+ + P+ P+ P + P Sbjct: 665 KVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV--STTDASPQSPPT-PQTTLTPLQESP 721 Query: 59 PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118 S+ QS P+ P P+ H P P + + S Sbjct: 722 ---VISKDQSPPPS-PPPSYHPPPP-------------PTKKPEVVVEAPSASETAEEPL 764 Query: 119 QYPVQPGAPGFYP---GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKR 175 Q P P P P S +F A++ + P G + +P L++ P A Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE--PAGPSGSPELVSSP--AASSS 820 Query: 176 ERKTIRIRDPNQGGKDITEEIMSGARTA---------STPTPPQTGGGLEPQANGE---T 223 ++I+ P + A +A P GGG + G T Sbjct: 821 SATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880 Query: 224 PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ-PSSPSPTPSPSPVLEPGSEPNLAV 282 P + +VR RS GA G P P PS Q P + + SPV P S + AV Sbjct: 881 PSLLQMVRL--RSVGA----PGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAV 934 Query: 283 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 342 + ++ E ++ G P EP P P SK S Sbjct: 935 ------RLKACSLAASEGLSSAQPNGPP---EAEPRPPQSPASTASFIFSK-------GS 978 Query: 343 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEE 402 LQ P++ T + N L E+ S E PP A P +SP P A+ Sbjct: 979 RKLQLERPVSPETQADLQRN-------LVAELRSISEQRPPQA-PKKSPKAPPPVARKPS 1030 Query: 403 LLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 462 + G P P A P+ P A P TAP ++ + E Sbjct: 1031 V--GVPPP----------------------ASPSYPRAEPLTAPPTNGLPHTQDRTKREL 1066 Query: 463 EEEG 466 E G Sbjct: 1067 AENG 1070 Score = 39.3 bits (90), Expect = 0.031 Identities = 57/256 (22%), Positives = 87/256 (33%), Gaps = 29/256 (11%) Query: 254 PSESQPSSPSPTPSPSP----VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 309 P PSS S T S S ++ GS LS G + + S ++ + G Sbjct: 404 PRSRHPSSSSDTWSHSQSSDTIVSDGS-----TLSSKGGSEGQPESSTASNSVVPPPQGG 458 Query: 310 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369 R SP AE + + S + S L+ P P T +H+ VP Sbjct: 459 SGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGP 518 Query: 370 L----EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPS-PPAVDLSPVSEPE-- 422 L +PE + P+L PP AP P + P P P PE Sbjct: 519 LGLPPKPERKQQPQLPRPPTTGGSEGAGAAP-CPPNPANSWVPGLSPGGSRRPPRSPERT 577 Query: 423 -EQAKEVTASMAPPTIPS---ATPATAPSATSPAQEEEMEEEEEEEEGE--------AGE 470 + ++ PT+P A P +P P + E + + Sbjct: 578 LSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS 637 Query: 471 AGEAESEKGGEELLPP 486 + A S++ G ++L P Sbjct: 638 SDPAPSDRSGPQILTP 653 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 79.0 bits (193), Expect = 4e-14 Identities = 115/506 (22%), Positives = 165/506 (32%), Gaps = 109/506 (21%) Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71 P P P P+P P + + +A + P + + P P + + SA P Sbjct: 716 PPPRPTAPKPLLPRREES-------EAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATP 768 Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131 P+ P S P +S P G TY PTQ +QP APG P Sbjct: 769 LHFPPS----PFPSSTGPGPHYLSGPLPPG----------TYSGPTQL--IQPRAPG--P 810 Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD 191 A P VAP P L P A E + P G Sbjct: 811 HAMP----------------------VAPGPALYPAP---AYTPELGLVPRSSPQHG--- 842 Query: 192 ITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPE 251 ++S P PP G P P++A+ VRP + +I A P P Sbjct: 843 ----VVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPR 898 Query: 252 HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 311 +P+ + P P P P P+ P + P A IP + + P Sbjct: 899 PNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP--------- 949 Query: 312 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 371 R+ P+P P + P P F P Q P PL + + G++P + Sbjct: 950 RIGPQPQPHPQ-----------PHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998 Query: 372 PEVESSPELAPPP--------ACPSESPVPI----------APTAQPEELLNGAPSPPAV 413 P L PP P++ P+P P P L P+P Sbjct: 999 PYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTR 1058 Query: 414 DLSPVSEPEEQAKEVTASMAPPT---IPSATPATAPSATSPAQEEEMEEEEEEEEGEA-- 468 + P + P +A + P+ +PS P+ P P + E G A Sbjct: 1059 PMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPV-PPRPPAAEPPPCLRRGAAAA 1117 Query: 469 --------GEAGEAESEKGGEELLPP 486 + G +S GG+ LL P Sbjct: 1118 DLLSSSPESQHGGTQSPGGGQPLLQP 1143 Score = 60.5 bits (145), Expect = 1e-08 Identities = 78/286 (27%), Positives = 102/286 (35%), Gaps = 50/286 (17%) Query: 5 PQSTGPPPAPSPGLPQPAF--PPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62 P T P P P+P P P F PP Q P ++ P + P+Q HF S P Sbjct: 892 PSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ--HHF--SSGIPAGFP 947 Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQQYP 121 A R+ P P H P SQ P Q P Q + P Q + P YP Sbjct: 948 APRI------GPQPQPHPQPHPSQAFGPQPPQQPLPL-QHPHLFPPQAPG-LLPPQSPYP 999 Query: 122 V--QPGAPG---------FYPGASPTEFGTYAGAY-YPAQGVQQ---FPTGVAPAPVLMN 166 QPG G YPG + ++GA +P+ G Q P PAP Sbjct: 1000 YAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRP 1059 Query: 167 QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226 PQ AP + IR P+ G+ +P P G + P+ P Sbjct: 1060 MGPQAAP------LTIRGPSSAGQS-----TPSPHLVPSPAPSPGPGPVPPRPPAAEP-- 1106 Query: 227 AVIVRPDDRSQGAIIAD-RPGLPGPEHSPSESQPSSPSPTPSPSPV 271 P +GA AD P +H ++S P P P+ V Sbjct: 1107 -----PPCLRRGAAAADLLSSSPESQHGGTQS-PGGGQPLLQPTKV 1146 Score = 54.3 bits (129), Expect = 9e-07 Identities = 78/284 (27%), Positives = 102/284 (35%), Gaps = 47/284 (16%) Query: 10 PPPAPSPGLPQPAFPPGQTAPVV---FSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRV 66 PP A P P P F + A V +T + Q PS P+ A PP Sbjct: 855 PPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFP--- 911 Query: 67 QSAAPARPGPAAHVYPAGSQVMMIPSQISY----PASQGAYYI-PGQGRSTYVVPTQQYP 121 P +P P + YPAG++ IP+Q + PA A I P P+Q + Sbjct: 912 --VPPPQPLPTPYTYPAGAK-QPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFG 968 Query: 122 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPP-----QIAPKRE 176 QP P P F A P Q P AP P ++ QPP Q+ P Sbjct: 969 PQPPQQPL-PLQHPHLFPPQAPGLLPPQS----PYPYAPQPGVLGQPPPPLHTQLYPGPA 1023 Query: 177 RKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRS 236 + + SGA +P PPQ P A G P RP Sbjct: 1024 QDPLPAH--------------SGALPFPSPGPPQPPH--PPLAYGPAPS----TRPMGPQ 1063 Query: 237 QGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPV--LEPGSEP 278 + P G + +PS SP+P+P P PV P +EP Sbjct: 1064 AAPLTIRGPSSAG-QSTPSPHLVPSPAPSPGPGPVPPRPPAAEP 1106 Score = 33.5 bits (75), Expect = 1.7 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%) Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61 ++P ++ P PA PGLP + P ++ P+ S+P P P+ P + PSS Sbjct: 1514 ESPVASLPGPAEPPGLPPASLP--ESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSS 1570 Score = 32.3 bits (72), Expect = 3.8 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 15/127 (11%) Query: 319 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 378 P +P+ ++ +P+ L P++S I + + + P LE V S P Sbjct: 1464 PPCKPLASASISQKNHLPQDS-QDLVLGGDVPISSIQATIAKLS-IRPPGGLESPVASLP 1521 Query: 379 ELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 438 A PP P P + PE + SPP P+S P +A + P P Sbjct: 1522 GPAEPPGLP--------PASLPESTPIPSSSPP-----PLSSPLPEAPQPKEEPPVPEAP 1568 Query: 439 SATPATA 445 S+ P ++ Sbjct: 1569 SSGPPSS 1575 >gi|169212085 PREDICTED: similar to poly(A) binding protein interacting protein 1 [Homo sapiens] Length = 516 Score = 77.8 bits (190), Expect = 8e-14 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%) Query: 683 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 733 P R P G LP L P+++ + +P+ ++A VL ++ + +N E Sbjct: 115 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 173 Query: 734 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 788 S + G ED V+ LN LT P F+ ++Q + + Sbjct: 174 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 228 Query: 789 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 848 T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+ Sbjct: 229 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 284 Query: 849 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 907 E+E +K++ + ++ R+R + F+GEL+ Sbjct: 285 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 317 Query: 908 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 953 L++ + + + + + L N +++L C +LL G L+ EK K Sbjct: 318 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 377 Query: 954 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990 M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 378 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 414 >gi|239752553 PREDICTED: similar to poly(A) binding protein interacting protein 1 [Homo sapiens] Length = 457 Score = 77.8 bits (190), Expect = 8e-14 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%) Query: 683 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 733 P R P G LP L P+++ + +P+ ++A VL ++ + +N E Sbjct: 56 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 114 Query: 734 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 788 S + G ED V+ LN LT P F+ ++Q + + Sbjct: 115 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 169 Query: 789 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 848 T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+ Sbjct: 170 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 225 Query: 849 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 907 E+E +K++ + ++ R+R + F+GEL+ Sbjct: 226 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 258 Query: 908 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 953 L++ + + + + + L N +++L C +LL G L+ EK K Sbjct: 259 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 318 Query: 954 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990 M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 319 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 355 >gi|89041275 PREDICTED: similar to poly(A) binding protein interacting protein 1 [Homo sapiens] Length = 488 Score = 77.8 bits (190), Expect = 8e-14 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%) Query: 683 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 733 P R P G LP L P+++ + +P+ ++A VL ++ + +N E Sbjct: 87 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 145 Query: 734 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 788 S + G ED V+ LN LT P F+ ++Q + + Sbjct: 146 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 200 Query: 789 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 848 T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+ Sbjct: 201 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 256 Query: 849 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 907 E+E +K++ + ++ R+R + F+GEL+ Sbjct: 257 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 289 Query: 908 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 953 L++ + + + + + L N +++L C +LL G L+ EK K Sbjct: 290 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 349 Query: 954 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990 M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 350 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 386 >gi|34452730 poly(A) binding protein interacting protein 1 isoform 3 [Homo sapiens] Length = 367 Score = 77.4 bits (189), Expect = 1e-13 Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 57/300 (19%) Query: 711 EPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNK 770 +P+ ++A VLM++ + +N E S + G ED L V+ LN Sbjct: 3 KPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TLSEYVQDFLNH 56 Query: 771 LT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 825 LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS A +C L Sbjct: 57 LTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHH 116 Query: 826 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 885 + + NFR+LLL RC+ E+E +K++ Sbjct: 117 LTISPQSG----NFRQLLLQRCRTEYE---------------------------VKDQAA 145 Query: 886 EARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLKNHDEESLE 933 + ++ R+R + F+GEL+ L++ + + + + + L N +++L Sbjct: 146 KGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLI 205 Query: 934 CLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990 C +LL G L+ EK K M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 206 CAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 265 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 77.4 bits (189), Expect = 1e-13 Identities = 129/506 (25%), Positives = 176/506 (34%), Gaps = 98/506 (19%) Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQAT--QMNTPSQPRQHFYPSRAQPPSSA 62 P S P+ P PA P T + P + +NTP QP + A Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD--------GLVQPATPA 609 Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122 A+ ++A PA PA S + P + P +Q P P P Sbjct: 610 AATGEAAPVLTVQPAPQAPPAVSTPL--PLGLQQPQAQQPPQAP--------TPQAAAPP 659 Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRI 182 Q P PG + + P + V P P +L Q+ +ER + Sbjct: 660 QATTPQPSPGLASS----------PEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL 709 Query: 183 RDPNQGGKDITEEIMSGARTASTP---TPPQTGGGLEPQANG---------ETPQVAVIV 230 I+S A P TP G GL PQA + P A + Sbjct: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769 Query: 231 RPDDRSQGAI-----IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL----- 280 P S ++ + D P LP P + S+P S P V P SEP L Sbjct: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS-----RPQSVSRPPSEPPLHPCPP 824 Query: 281 --AVLSIPGDTMTTIQMSVEE--STPISRETGEPYR-LSPEPTPLAEPILEVE----VTL 331 A ++PG + Q+ V S P G P L P+ P P+ + Sbjct: 825 PQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSST 884 Query: 332 SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES- 390 S V S +SS L APTP + ++ G S P + PE A PP P + Sbjct: 885 SSAVASSSETSSRLPAPTP-SDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTF 943 Query: 391 -----PVPIAPTAQPEELLN----------------GAPSPP--AVDLSPVSEPEEQAKE 427 P P P QP+ LL GAP+ P + L P++ P A Sbjct: 944 QMVTTPFPALP--QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPA--ASV 999 Query: 428 VTASMAP---PTIPSATPATAPSATS 450 + + AP PT PS PA AP A + Sbjct: 1000 LVSGQAPSGTPTAPSHAPAPAPMAAT 1025 Score = 66.6 bits (161), Expect = 2e-10 Identities = 142/615 (23%), Positives = 230/615 (37%), Gaps = 114/615 (18%) Query: 4 APQST--GPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61 AP T G P A +PGL P ++ TP TP QP+ P+ PP Sbjct: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNV-ILHRTP------TPIQPK----PAGVLPPKL 363 Query: 62 AASRVQSAAPARPGPAAHVYPAG-SQVMMIPSQISYPASQGAYYIPGQG--RSTYVVPTQ 118 + APA P Q P +++ A+ A GQ S + P Sbjct: 364 YQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA----GQNVVLSGFPAPAL 419 Query: 119 QYPVQPGAPGFYPGASPTE-------------FGTYAGAYYPAQ----GVQQFPTGVAPA 161 Q V P GA+P + + PAQ G QF APA Sbjct: 420 QANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPA 479 Query: 162 PVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANG 221 L Q + + + P+ GG+ I I++ A P G L P + Sbjct: 480 VQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAG---PLSLGPVLAPHSGA 536 Query: 222 ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLA 281 + + + P Q A+ P P++SQP+ P + + VL+ + P A Sbjct: 537 HSAHI-LSAAPIQVGQPALF-QMPVSLAAGSLPTQSQPAPAGP--AATTVLQGVTLPPSA 592 Query: 282 VLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFS 341 V + T V+ +TP + TGE A P+L V+ P P++ Sbjct: 593 VAML-----NTPDGLVQPATPAAA-TGE-----------AAPVLTVQ-----PAPQA--- 627 Query: 342 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE 401 P TPL P G+ + +P +P+ A PP + P P + PE Sbjct: 628 --PPAVSTPL---------PLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP-GLASSPE 675 Query: 402 ELLNGAP---SPPAV---DLSPVSEPEEQAKEVTASMAPP-TIPSATPATAPSATSPAQE 454 +++ G P +P A+ D + P+E++++ ++ P ++P++ +AP PAQ+ Sbjct: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP---PPAQD 732 Query: 455 EEMEEEEEEEEGEAGEAGEAESEKGGEELLP---------PESTP-----IPANLSQNLE 500 + G +A ++++ +P P S+P P S +L Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792 Query: 501 AAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVP---EVENQ---PPAGSNP 554 + T+ P R + + + + +A P +P ++NQ PP SNP Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPP--PQAPPTLPGIFVIQNQLGVPPPASNP 850 Query: 555 GPESEGSGVPP-RPE 568 P + G PP RP+ Sbjct: 851 APTAPGPPQPPLRPQ 865 Score = 65.9 bits (159), Expect = 3e-10 Identities = 114/502 (22%), Positives = 170/502 (33%), Gaps = 95/502 (18%) Query: 11 PPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQ--- 67 PPA + G P P + P+ S Q ++ P QH P + Q A VQ Sbjct: 427 PPATTTGAAPPQPPGALSKPM--SVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484 Query: 68 --SAAPARPGP---AAHVYPAGSQVMMIP----SQISYPASQGAYYIPGQG-RSTYVVPT 117 SA PA G AA G Q++ P ++ P S G P G S +++ Sbjct: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSA 544 Query: 118 QQYPVQPGAPGFYPGASPTEFGTYAGAYYPA----------QGVQQFPTGVA----PAPV 163 P+Q G P + G+ PA QGV P+ VA P + Sbjct: 545 A--PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGL 602 Query: 164 LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGET 223 + P A + ++ Q ++ + G + PPQ P Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQA-----PTPQAAA 657 Query: 224 PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP---------------SP 268 P A +P PGL QP S +PT S Sbjct: 658 PPQATTPQPS-----------PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706 Query: 269 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE---STPISRETG-EPYRLSPEPTPLAEPI 324 P+ G LS+P + + ++ +TP+++ G P + +P P Sbjct: 707 QPLSAEGPH-----LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761 Query: 325 LEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH--EPNGMVPSEDLEPEVESSPELAP 382 + L P P S S P QAP + H H P PS P+ S P P Sbjct: 762 IPAAAPLKGPGPSSS-PSLPHQAPLGDSPHLPSPHPTRPPSRPPSR---PQSVSRPPSEP 817 Query: 383 P--PACPSESPVPIA-------------PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 427 P P P ++P + P + P AP PP L P S+P E Sbjct: 818 PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT---APGPPQPPLRPQSQPPEGPLP 874 Query: 428 VTASMAPPTIPSATPATAPSAT 449 + P + SA +++ +++ Sbjct: 875 PAPHLPPSSTSSAVASSSETSS 896 Score = 64.7 bits (156), Expect = 7e-10 Identities = 151/614 (24%), Positives = 215/614 (35%), Gaps = 95/614 (15%) Query: 11 PPAPSPGLPQ-----PAFPPGQ--------TAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57 P AP+ LPQ PA GQ T + + P T N P A Sbjct: 475 PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP--LSLGPVLAP 532 Query: 58 PPSSAASRVQSAAPARPG-PAAHVYPAGSQVMMIPSQISYPASQG-AYYIPGQGRSTYVV 115 + ++ + SAAP + G PA P +P+Q S PA G A QG + Sbjct: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQ-SQPAPAGPAATTVLQG---VTL 588 Query: 116 PTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVA-PAPVLMNQP------ 168 P + G A+P A Q Q P V+ P P+ + QP Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPP 648 Query: 169 ----PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLE---PQANG 221 PQ A + T + P+ G E+I+ G ++TPT T L+ PQ Sbjct: 649 QAPTPQAAAPPQATTPQ---PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS 705 Query: 222 ETPQVA-----------VIVRP---DDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 267 + P A ++ P D + +A GL GP+ S++ P+ P+ Sbjct: 706 QQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQIPA 764 Query: 268 PSPVLEPG--SEPNLAVLSIPGDTM------TTIQMSVEESTP--ISRETGEPYRLSPEP 317 +P+ PG S P+L + GD+ T S S P +SR EP L P P Sbjct: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP-PLHPCP 823 Query: 318 TPLAEPILE----VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 373 P A P L ++ L P P S + +P P + P G +P P Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPAS--NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPP 881 Query: 374 VESSPELAPPPACPSESPVPIAPTAQ----PEELLNGAPSPPAVDLSPVSEPEEQAKEVT 429 +S +A S P P Q P + + +P+PP L V EP Sbjct: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPT-LHLVPEPA------- 933 Query: 430 ASMAPPTIPSAT--PATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPE 487 APP P T T P P + +E + G +++ GG P Sbjct: 934 ---APPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGII-----LQNKAGGAPAAPQT 985 Query: 488 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG--DLLDAFKEANPA-VPEV 544 ST + S + Q P A G LL A +A + +P + Sbjct: 986 STSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL 1045 Query: 545 ENQPPAGSNPGPES 558 A S PG S Sbjct: 1046 NVAKAASSGPGKPS 1059 Score = 38.1 bits (87), Expect = 0.069 Identities = 61/279 (21%), Positives = 90/279 (32%), Gaps = 49/279 (17%) Query: 2 NKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61 N AP + GPP P PQ+ P P H PS + Sbjct: 849 NPAPTAPGPPQPP-------------------LRPQSQPPEGPLPPAPHLPPSSTSSAVA 889 Query: 62 AASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYP 121 ++S S PA P P+ Q+ +P SQG + P + ++VP P Sbjct: 890 SSSETSSRLPA-PTPS-------------DFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP 935 Query: 122 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP--PQIAPKRERKT 179 P F +P F + Q P+G+ +L N+ AP+ Sbjct: 936 PPPPPRTFQMVTTP--FPALPQPKALLERFHQVPSGI----ILQNKAGGAPAAPQTSTSL 989 Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQ-ANGETPQVAVIVRPDDRSQG 238 + P ++SG + TPT P P A G P + + + Sbjct: 990 GPLTSP------AASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLP 1043 Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSE 277 + + GP PS Q S P L+P E Sbjct: 1044 TLNVAKAASSGP-GKPSGLQYESKLSGLKKPPTLQPSKE 1081 Score = 33.9 bits (76), Expect = 1.3 Identities = 82/378 (21%), Positives = 126/378 (33%), Gaps = 64/378 (16%) Query: 231 RPDD-----RSQGA-IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEP---------G 275 +PD+ RS G I A G P H P S S+P + P P L G Sbjct: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSS--SAPGASTQPPPHLPTKLVIRHGGAG 1254 Query: 276 SEPNL-------AVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI-LEV 327 P++ ++ S + + +E P+ P + + + + ++ Sbjct: 1255 GSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQ 1314 Query: 328 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 387 E LSK V + P+ P P + T+++ EP P + PPPA P Sbjct: 1315 EAGLSKVVHNTALD--PVHQPPPPPA-TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371 Query: 388 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 447 P L AP P + L K ++ P P TPA Sbjct: 1372 ERKP------------LGTAPHCPRLPL---------RKTYRENVGGPGAPEGTPAGRAR 1410 Query: 448 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 507 SPA + +E G E E E L P P PA + + Sbjct: 1411 GGSPAPLP--AKVDEATSGLIRELAAVEDELYQRMLKGP--PPEPAASAAQGTGDPDWEA 1466 Query: 508 AVSVPKRRRKIKELNKKEAV--------GDLLDAFKEANPAVPEVENQP---PAGSNPGP 556 P +RRK + + +A L + + A ++ ++ P PA S P Sbjct: 1467 PGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA 1526 Query: 557 ESEGSGVPPRPEEADETW 574 S G+ P P E + Sbjct: 1527 ASAGTPASPPPLHRPEAY 1544 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.130 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,278,230 Number of Sequences: 37866 Number of extensions: 4655385 Number of successful extensions: 59037 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 434 Number of HSP's successfully gapped in prelim test: 2065 Number of HSP's that attempted gapping in prelim test: 29736 Number of HSP's gapped (non-prelim): 20133 length of query: 1599 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1483 effective length of database: 13,855,062 effective search space: 20547056946 effective search space used: 20547056946 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.