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Search of human proteins with 38201621
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
(1599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 3190 0.0
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 3190 0.0
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 3010 0.0
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 2849 0.0
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 1273 0.0
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 196 2e-49
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 196 2e-49
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 1e-20
gi|163965366 nascent polypeptide-associated complex alpha subuni... 94 1e-18
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 85 5e-16
gi|150170670 piccolo isoform 2 [Homo sapiens] 84 1e-15
gi|150378539 piccolo isoform 1 [Homo sapiens] 84 1e-15
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 84 1e-15
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 84 1e-15
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 84 1e-15
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 84 1e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 83 2e-15
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 82 4e-15
gi|112421108 capicua homolog [Homo sapiens] 82 4e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 81 7e-15
gi|33386693 poly(A) binding protein interacting protein 1 isofor... 81 9e-15
gi|17511255 poly(A) binding protein interacting protein 1 isofor... 81 9e-15
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 79 3e-14
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 79 4e-14
gi|169212085 PREDICTED: similar to poly(A) binding protein inter... 78 8e-14
gi|239752553 PREDICTED: similar to poly(A) binding protein inter... 78 8e-14
gi|89041275 PREDICTED: similar to poly(A) binding protein intera... 78 8e-14
gi|34452730 poly(A) binding protein interacting protein 1 isofor... 77 1e-13
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 77 1e-13
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 3190 bits (8271), Expect = 0.0
Identities = 1599/1599 (100%), Positives = 1599/1599 (100%)
Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS
Sbjct: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120
SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY
Sbjct: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120
Query: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180
PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI
Sbjct: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180
Query: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240
RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI
Sbjct: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240
Query: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300
IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES
Sbjct: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300
Query: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360
TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE
Sbjct: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360
Query: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420
PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE
Sbjct: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420
Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480
PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG
Sbjct: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480
Query: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540
EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA
Sbjct: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540
Query: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600
VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ
Sbjct: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600
Query: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660
WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI
Sbjct: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660
Query: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720
NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL
Sbjct: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720
Query: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780
MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM
Sbjct: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780
Query: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840
KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR
Sbjct: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840
Query: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900
KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK
Sbjct: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900
Query: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960
FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN
Sbjct: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960
Query: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020
QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV
Sbjct: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020
Query: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080
QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS
Sbjct: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080
Query: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140
NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV
Sbjct: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140
Query: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200
VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ
Sbjct: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200
Query: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260
PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK
Sbjct: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260
Query: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320
EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY
Sbjct: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320
Query: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380
EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL
Sbjct: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380
Query: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440
GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS
Sbjct: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440
Query: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500
EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD
Sbjct: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500
Query: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560
VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF
Sbjct: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560
Query: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599
YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 3190 bits (8271), Expect = 0.0
Identities = 1599/1599 (100%), Positives = 1599/1599 (100%)
Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS
Sbjct: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120
SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY
Sbjct: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120
Query: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180
PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI
Sbjct: 121 PVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTI 180
Query: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240
RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI
Sbjct: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240
Query: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300
IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES
Sbjct: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300
Query: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360
TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE
Sbjct: 301 TPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE 360
Query: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420
PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE
Sbjct: 361 PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE 420
Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480
PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG
Sbjct: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480
Query: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540
EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA
Sbjct: 481 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPA 540
Query: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600
VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ
Sbjct: 541 VPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQ 600
Query: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660
WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI
Sbjct: 601 WKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGI 660
Query: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720
NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL
Sbjct: 661 NCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVL 720
Query: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780
MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM
Sbjct: 721 MTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLM 780
Query: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840
KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR
Sbjct: 781 KQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFR 840
Query: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900
KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK
Sbjct: 841 KLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIK 900
Query: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960
FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN
Sbjct: 901 FIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFN 960
Query: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020
QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV
Sbjct: 961 QMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKV 1020
Query: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080
QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS
Sbjct: 1021 QQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDS 1080
Query: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140
NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV
Sbjct: 1081 NNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRV 1140
Query: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200
VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ
Sbjct: 1141 VQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200
Query: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260
PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK
Sbjct: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMK 1260
Query: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320
EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY
Sbjct: 1261 EAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLY 1320
Query: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380
EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL
Sbjct: 1321 EILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEIL 1380
Query: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440
GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS
Sbjct: 1381 GLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPS 1440
Query: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500
EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD
Sbjct: 1441 EELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVD 1500
Query: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560
VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF
Sbjct: 1501 VAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAF 1560
Query: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599
YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1561 YSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 3010 bits (7804), Expect = 0.0
Identities = 1512/1512 (100%), Positives = 1512/1512 (100%)
Query: 88 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 147
MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP
Sbjct: 1 MMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYP 60
Query: 148 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 207
AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT
Sbjct: 61 AQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT 120
Query: 208 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 267
PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS
Sbjct: 121 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 180
Query: 268 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 327
PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV
Sbjct: 181 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 240
Query: 328 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 387
EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP
Sbjct: 241 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 300
Query: 388 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 447
SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS
Sbjct: 301 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 360
Query: 448 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 507
ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV
Sbjct: 361 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 420
Query: 508 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 567
AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP
Sbjct: 421 AVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRP 480
Query: 568 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 627
EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM
Sbjct: 481 EEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 540
Query: 628 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 687
QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG
Sbjct: 541 QKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGG 600
Query: 688 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 747
PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR
Sbjct: 601 PGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDR 660
Query: 748 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 807
GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS
Sbjct: 661 GEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAIS 720
Query: 808 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 867
EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE
Sbjct: 721 EPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKE 780
Query: 868 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 927
MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH
Sbjct: 781 MDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNH 840
Query: 928 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 987
DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG
Sbjct: 841 DEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRG 900
Query: 988 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 1047
SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV
Sbjct: 901 SNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLV 960
Query: 1048 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1107
DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD
Sbjct: 961 DDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSD 1020
Query: 1108 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1167
AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG
Sbjct: 1021 AASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERG 1080
Query: 1168 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1227
GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL
Sbjct: 1081 GDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL 1140
Query: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1287
PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL
Sbjct: 1141 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTL 1200
Query: 1288 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1347
ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI
Sbjct: 1201 ERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPI 1260
Query: 1348 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1407
LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL
Sbjct: 1261 LQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFL 1320
Query: 1408 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1467
PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN
Sbjct: 1321 PEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEAN 1380
Query: 1468 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1527
LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA
Sbjct: 1381 LSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYA 1440
Query: 1528 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1587
LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK
Sbjct: 1441 LQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFK 1500
Query: 1588 WLREAEEESDHN 1599
WLREAEEESDHN
Sbjct: 1501 WLREAEEESDHN 1512
Score = 33.5 bits (75), Expect = 1.7
Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)
Query: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57
P S P P+PSP L + P PG T + + + +TP R+ P R
Sbjct: 172 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 227
Query: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113
P P+ A + P S+ P Q P + I G S
Sbjct: 228 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 282
Query: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173
+ P + + P P SP P ++ G AP+P ++ P
Sbjct: 283 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 330
Query: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233
+ +P + K++T + + PT P P A Q + +
Sbjct: 331 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 374
Query: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292
+ +G A G E E P +P P+ S LE + +AV S+P
Sbjct: 375 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 431
Query: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349
+++ +E+ G+ E P + S P PESE S P +A
Sbjct: 432 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 485
Query: 350 PLASHTVEIHEPNGMVPSE 368
S +IH + P E
Sbjct: 486 TWDSKEDKIHNAENIQPGE 504
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 2849 bits (7386), Expect = 0.0
Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)
Query: 165 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 224
MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP
Sbjct: 1 MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60
Query: 225 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 284
QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS
Sbjct: 61 QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
Query: 285 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 344
IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP
Sbjct: 121 IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180
Query: 345 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 404
LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL
Sbjct: 181 LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
Query: 405 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 464
NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE
Sbjct: 241 NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300
Query: 465 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524
EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK
Sbjct: 301 EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360
Query: 525 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 584
EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA
Sbjct: 361 EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420
Query: 585 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 644
ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA
Sbjct: 421 ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480
Query: 645 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 704
NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS
Sbjct: 481 NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540
Query: 705 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 764
QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV
Sbjct: 541 QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
Query: 765 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 824
RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA
Sbjct: 601 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
Query: 825 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 884
LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL
Sbjct: 661 LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720
Query: 885 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 944
EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK
Sbjct: 721 EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780
Query: 945 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 1004
DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ
Sbjct: 781 DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840
Query: 1005 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 1064
IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI
Sbjct: 841 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900
Query: 1065 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 1124
DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS
Sbjct: 901 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960
Query: 1125 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1184
ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR
Sbjct: 961 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020
Query: 1185 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1244
SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK
Sbjct: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080
Query: 1245 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1304
KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL
Sbjct: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140
Query: 1305 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1364
LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK
Sbjct: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200
Query: 1365 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1424
PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY
Sbjct: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260
Query: 1425 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1484
TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT
Sbjct: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320
Query: 1485 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1544
AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM
Sbjct: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380
Query: 1545 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599
FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
Score = 33.5 bits (75), Expect = 1.7
Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)
Query: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57
P S P P+PSP L + P PG T + + + +TP R+ P R
Sbjct: 95 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 150
Query: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113
P P+ A + P S+ P Q P + I G S
Sbjct: 151 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205
Query: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173
+ P + + P P SP P ++ G AP+P ++ P
Sbjct: 206 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 253
Query: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233
+ +P + K++T + + PT P P A Q + +
Sbjct: 254 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 297
Query: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292
+ +G A G E E P +P P+ S LE + +AV S+P
Sbjct: 298 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 354
Query: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349
+++ +E+ G+ E P + S P PESE S P +A
Sbjct: 355 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 408
Query: 350 PLASHTVEIHEPNGMVPSE 368
S +IH + P E
Sbjct: 409 TWDSKEDKIHNAENIQPGE 427
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 2784 bits (7218), Expect = 0.0
Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)
Query: 197 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 256
MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
Query: 257 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316
SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
Query: 317 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 376
PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
Query: 377 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436
SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
Query: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 496
IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
Query: 497 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 556
QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
Query: 557 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 616
ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
Query: 617 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 676
LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
Query: 677 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 736
TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
Query: 737 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 796
SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
Query: 797 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 856
VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
Query: 857 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 916
DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
Query: 917 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 976
HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
Query: 977 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 1036
FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
Query: 1037 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1096
GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
Query: 1097 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1156
SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
Query: 1157 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1216
RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
Query: 1217 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1276
GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
Query: 1277 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1336
IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
Query: 1337 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1396
WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
Query: 1397 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1456
REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
Query: 1457 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1516
NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
Query: 1517 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1576
DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
Query: 1577 VALKSVTAFFKWLREAEEESDHN 1599
VALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 VALKSVTAFFKWLREAEEESDHN 1403
Score = 33.5 bits (75), Expect = 1.7
Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)
Query: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57
P S P P+PSP L + P PG T + + + +TP R+ P R
Sbjct: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 118
Query: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113
P P+ A + P S+ P Q P + I G S
Sbjct: 119 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173
Query: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173
+ P + + P P SP P ++ G AP+P ++ P
Sbjct: 174 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 221
Query: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233
+ +P + K++T + + PT P P A Q + +
Sbjct: 222 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 265
Query: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292
+ +G A G E E P +P P+ S LE + +AV S+P
Sbjct: 266 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 322
Query: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349
+++ +E+ G+ E P + S P PESE S P +A
Sbjct: 323 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 376
Query: 350 PLASHTVEIHEPNGMVPSE 368
S +IH + P E
Sbjct: 377 TWDSKEDKIHNAENIQPGE 395
>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
sapiens]
Length = 1585
Score = 1273 bits (3294), Expect = 0.0
Identities = 808/1669 (48%), Positives = 1006/1669 (60%), Gaps = 194/1669 (11%)
Query: 41 MNTPSQPRQHFYPS-RAQPPSSAASRVQSAAPARPG---PAAHVYPAGSQVMMIPS-QIS 95
MN+ Q R F+ + QPP A+ S+ RPG P A VY A +MM+ +
Sbjct: 1 MNSQPQTRSPFFQRPQIQPPR--ATIPNSSPSIRPGAQTPTA-VYQANQHIMMVNHLPMP 57
Query: 96 YPASQGAYYIPGQGRST---YVVPTQQYPVQPGAPG-FYPGASPTEF-GTYAGAYYPAQG 150
YP QG Y Q R + YV P QQYPVQP PG FYPG P +F Y +YP+Q
Sbjct: 58 YPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQP 117
Query: 151 VQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA---------- 200
V Q + P QPP KRE+KTIRIRDPNQGGKDITEEIMSG
Sbjct: 118 VYQSAPIIVPT---QQQPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIG 172
Query: 201 RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 260
R STPTPPQ L Q +P V V + A +A + E +P
Sbjct: 173 RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223
Query: 261 SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 302
SPSPVL E + ++A L +P T++++ S +
Sbjct: 224 PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283
Query: 303 ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 349
S + +P SP + P L S P+P +E + P
Sbjct: 284 SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343
Query: 350 ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 405
PL S T I+E NG+ SE L ES E+ P + I E L
Sbjct: 344 PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400
Query: 406 GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 461
P+P ++P + P T +PP P PA A + +SP+ + +EE+E
Sbjct: 401 CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456
Query: 462 E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 510
E+ E E E++ EE+L ++ +P+PA Q+A++
Sbjct: 457 SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504
Query: 511 VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 566
VPK +K K+ + +E + L+ E ++ +V + G PE + S + +
Sbjct: 505 VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563
Query: 567 PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 611
+ +E + E + AE++ GE + +K + WKP + E KK+
Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623
Query: 612 YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 669
YDREFLL FQF+ A +QKPEGLP ISDVVLDK N K P+R LDP L GPDFTP+
Sbjct: 624 YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680
Query: 670 FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 729
FA+ GR T RG P +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 681 FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728
Query: 730 AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 789
AE AWKPS KR D +D + KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 729 AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783
Query: 790 TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 849
TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP +KP TVNFRKLLLNRCQK
Sbjct: 784 TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843
Query: 850 EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 909
EFEKDK DD+VFEKKQKE++ A+ EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 844 EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903
Query: 910 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 969
MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 904 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963
Query: 970 KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 1029
KTSSRIRFMLQDV+DLR NWV RR DQGPKTI+QIHKEA++EE E KVQQLM K +
Sbjct: 964 KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021
Query: 1030 KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 1089
KRR G+ VD+GGWNTV +K SR +D S+ KITKP +ID QL
Sbjct: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071
Query: 1090 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 1141
SWGKGSSGG+ A +D A R + S+LNRFSALQ P+ ST D+RR +
Sbjct: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127
Query: 1142 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1200
R S+ RE+ +K R RGG D LD ++ EE+ RE
Sbjct: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176
Query: 1201 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1256
+ L + + RE+A P +S + KAALSEEELE+KSK+II+E+LH+
Sbjct: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236
Query: 1257 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1316
ND KEA+QCV+EL + LL +FVR GVESTLERS I R+HMGQLL+QL+ + LS ++
Sbjct: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296
Query: 1317 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1376
+G E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL E +KPL P+G+A LL
Sbjct: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356
Query: 1377 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1433
EIL LLCK M KKVG LWREA LSWK+FLPEG+D+ F+ EQK+++ + SEA
Sbjct: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416
Query: 1434 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1492
++ L +EEL ++LEKL+ E +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476
Query: 1493 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1550
+ + RVD AV+K R +L KYL D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536
Query: 1551 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599
DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585
>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
isoform 2 [Homo sapiens]
Length = 869
Score = 196 bits (498), Expect = 2e-49
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 707 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 763
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
Query: 764 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 823
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
Query: 824 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 929
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
Query: 930 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 988
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
Query: 989 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 1039
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
Score = 113 bits (282), Expect = 2e-24
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1286
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 492 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 551
Query: 1287 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1346
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 552 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 611
Query: 1347 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1406
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 612 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 666
Query: 1407 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1465
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 667 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 717
Query: 1466 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1510
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 718 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777
Query: 1511 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1569
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 778 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 836
Query: 1570 AEQQGKGVALKSVTAFFKWLREAEEE 1595
E GKG AL V + WL AEEE
Sbjct: 837 QEFPGKGKALFQVNQWLTWLETAEEE 862
>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
isoform 1 [Homo sapiens]
Length = 907
Score = 196 bits (498), Expect = 2e-49
Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)
Query: 707 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 763
G R P+ T +E + + A W P+ D A+ + D +FR+
Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80
Query: 764 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 823
VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L
Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139
Query: 824 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875
A P + P + FR+LL+++ Q EFE + +V++K++ +
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192
Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 929
L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247
Query: 930 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 988
E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307
Query: 989 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 1039
+WVPR+ D GPKTI+QI ++A +++ I SD GP PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359
Score = 113 bits (282), Expect = 2e-24
Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)
Query: 1228 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1286
P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + +
Sbjct: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589
Query: 1287 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1346
L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+
Sbjct: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649
Query: 1347 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1406
+ V + EL +PL G L L L L K + + L++++ ++ ++
Sbjct: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704
Query: 1407 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1465
LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+
Sbjct: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755
Query: 1466 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1510
N+S + V V LMT+ S+ + L + +L + +
Sbjct: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815
Query: 1511 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1569
+QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+
Sbjct: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874
Query: 1570 AEQQGKGVALKSVTAFFKWLREAEEE 1595
E GKG AL V + WL AEEE
Sbjct: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 100 bits (249), Expect = 1e-20
Identities = 113/461 (24%), Positives = 169/461 (36%), Gaps = 58/461 (12%)
Query: 11 PPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAA 70
PP+P P P PP +AP T + PSQ PS PP A +Q+
Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP----PSMTTPPMQAPPSLQTIP 387
Query: 71 PAR-------PGPAAHVYPAGSQVMMIPSQISYPASQGAYYI----PGQGRSTYVVPTQQ 119
P + P A P + + + P Q + P Q +++ P++
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
Query: 120 YPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKT 179
P +P P + A P Q T ++PA ++ P I P + +
Sbjct: 448 ASTPPDSP-------PLQAPLSLPASPPLQ------TSLSPAVSPLSSPLTIHPLQALSS 494
Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239
+ P ++ IM T S+ PP +TP ++ P +
Sbjct: 495 LASHSPQA---PLSSLIMPPLETQSSLAPPSL----------QTPPASLTTPPLENLPSL 541
Query: 240 IIADRPGLPGPEHSPSESQPSSPSPTP---SPSPVLEPGSEPNLAVLSIPGDTMTTIQMS 296
P +P P P+P P PSP+ P E ++ + P +
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA-- 599
Query: 297 VEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV 356
S P+ P P P A P L + + P P + SPL P+P A + +
Sbjct: 600 ---SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656
Query: 357 EIH---EPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 413
+H P PS ++ SP A PP PS +P AP + L PSPPA
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPF--SPP-ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713
Query: 414 D-LSPVSEPEEQAKEVTAS--MAPPTIPSATPATAPSATSP 451
+SP + P QA A+ + P P A+P +PSAT P
Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 88.2 bits (217), Expect = 6e-17
Identities = 117/490 (23%), Positives = 172/490 (35%), Gaps = 71/490 (14%)
Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71
P+ GL +PA ++ S+P + + PR +PS+ +P A R P
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131
R A + P S + PS P+ A +P + +P P +P P
Sbjct: 288 PRKDAAPALGPLSSSPLATPS----PSGTKARPVPPPDNAATPLPA----TLPPSP---P 336
Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAP--APVLMNQPPQIAPKRERKTIRIRDPNQGG 189
A+P + + P+ P P AP M PP AP +++ P Q
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP----SLQTIPPIQVP 392
Query: 190 KDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVA-----VIVRPDDRSQGAIIADR 244
+T + P P L+ + +P + + + P R
Sbjct: 393 HSLTSPSLQA------PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
Query: 245 PGLPGPEHSPSE---SQPSSPSPTPSPSPVLEPGSEP----NLAVLSIPGDTMTTIQMSV 297
P P+ P + S P+SP S SP + P S P L LS +S
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
Query: 298 EESTPISRETG-EPYRLSPEPTPLAEPILEVEVTL--------SKPVPESEFSSSPLQAP 348
P+ ++ P L P L P LE +L S P+ + P AP
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566
Query: 349 TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA----CPSESPVPIAPTAQPEEL- 403
PL + + P PS P ++ P LA PP P SP+ P P L
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
Query: 404 ---LNGAPSPPAVD-LSPVSEPEEQAKE------------------VTASMAPPTIPSAT 441
L PSPPA LSP++ P QA V A +PP P +
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 442 PATAPSATSP 451
P+ P + +P
Sbjct: 687 PSATPPSQAP 696
Score = 68.9 bits (167), Expect = 4e-11
Identities = 130/539 (24%), Positives = 174/539 (32%), Gaps = 62/539 (11%)
Query: 4 APQSTGPPPA-----PSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQP 58
AP S PPA P LP A PP QTA +TP + TP P P Q
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH---LETPPCPA----PCPLQA 571
Query: 59 PSSAASRVQSAAP---ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVV 115
P S + P A P P A A + +PS P S A P +
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP---PLSPLATPPPQAPPXLALP 628
Query: 116 PTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKR 175
P Q P P +P P A+P+ A A + + Q P P+P + Q P P
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVH----LLQAPFSPPPSPPV--QAPFSPPAS 682
Query: 176 ERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVR---- 231
+ P+Q + + S P P P P A ++
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 232 -PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTM 290
P P +P +P P SP + SP+ +P + A+ + P +
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 291 TTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP-- 348
+ S P S P P P A P+L + VP S +S LQAP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRR 857
Query: 349 TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 405
P + P + P P S L+ P S + T+ PEE L
Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LR 912
Query: 406 GAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEEM 457
G S P SP + E A A P P A P P AT P + +
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972
Query: 458 EEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 516
E E E+ + G P P A A + PK+ R
Sbjct: 973 CTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 67.0 bits (162), Expect = 1e-10
Identities = 110/476 (23%), Positives = 171/476 (35%), Gaps = 45/476 (9%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQM--------NTPSQPRQHFYPS 54
KA + P A +PGL P PPG P TP A ++ P R
Sbjct: 9 KAGAAARTPAARAPGLLTPR-PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 55 RAQPPSSA-ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGR-ST 112
P S+ A +SA + PA+ +G P++ + P G PG+ +T
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP---GPVSSPGRASGTT 124
Query: 113 YVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP---- 168
P Q ++ A TE + A+ PT P+P + +
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 169 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP---PQTGGGLEPQANGETPQ 225
++ R + R R P +G + + T +P P GGGL+ A+
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 226 VAVIVRPDDRS----QGAIIAD-RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL 280
A + RS +G A P P P+ + P P +P L P S L
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 281 AVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEF 340
A S G + +TP+ P L P P PLA P+ L+ P P +
Sbjct: 305 ATPSPSGTKARPVPPPDNAATPL------PATLPPSP-PLATPL-----PLAPPSPSAPP 352
Query: 341 SSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES----PVPIAP 396
S L P+P A+ + P+ P P +++ P + P + S S P P+A
Sbjct: 353 SLQTL--PSPPATPPSQA-PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 397 TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 452
++ G+P+ A P + +T+ P + P +P + PA
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Score = 40.0 bits (92), Expect = 0.018
Identities = 76/347 (21%), Positives = 116/347 (33%), Gaps = 53/347 (15%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
+AP S P SP A PP Q P + + P + P+ P PS PP +
Sbjct: 674 QAPFSPPASPPVSPS----ATPPSQAPPSLAAPPLQVPPSPPASPPMS--PSATPPPQAP 727
Query: 63 ASRVQSAAPARPGPAAH--VYPAGSQVMMIPSQISYPASQGAYYIPGQ-GRSTYVVPTQQ 119
P P A + P+ + +P ++ P Q P S P Q
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787
Query: 120 YP---------VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAP--APVLMNQP 168
P P P +PG +P + P+ + P P AP ++ P
Sbjct: 788 APPALATPPLQALPSPPASFPGQAP---------FSPSASLPMSPLATPPPQAPPVLAAP 838
Query: 169 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGAR--TASTPTPPQ----------TGGGLE 216
P + ++ P + + +SG R A P PP +G L
Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898
Query: 217 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLE--P 274
++ T + D +G A P P+ + P++ S P+P P
Sbjct: 899 GHSSSATSTPEELRGYDSGPEGGAAAS----PPPDAELAACHPAAWSRGPAPPLAFRGAP 954
Query: 275 GSEPNLAVLSIPG--DTMTTIQMSVEESTPISRETGEPYRLSPEPTP 319
G+ + PG D + TI E+ T P L P P+P
Sbjct: 955 GAPLPWPPATGPGSADGLCTIY----ETEGPESATPAPGALDPGPSP 997
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 93.6 bits (231), Expect = 1e-18
Identities = 142/585 (24%), Positives = 196/585 (33%), Gaps = 111/585 (18%)
Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAAS 64
P + P AP P P P G A T TP P+ A PP A
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL----ATPPPKGAP 1149
Query: 65 RVQSAAPARP-GPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQ 123
+A P P G A P G+ + P+ +G P S PT
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLATP----SPKGAPTTPAATP 1202
Query: 124 PGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIR 183
P G SP +G P P+P P +PK T
Sbjct: 1203 PSPKGGLATPSP-------------KGAPTTPAATPPSPKGGLATP--SPKGAPTTPAAT 1247
Query: 184 DPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 243
P+ G T GA T TPP GGL + P AV+ P +
Sbjct: 1248 PPSPKGGPATPP-PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG------- 1299
Query: 244 RPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPI 303
GP SP + P+ P+ TP PSP PG+ P + P T
Sbjct: 1300 -----GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVT-------------- 1339
Query: 304 SRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNG 363
P+P P L SK P + S + PTP A+ P
Sbjct: 1340 ------------PPSPKGTPTLPATTPSSKGGPTTPSSK---EGPTPPAATPSHKGGP-A 1383
Query: 364 MVPSEDLEPEVESSPELAPPPACP-SESPVPIAPTAQPEELL--NGAPSPPAVDLSPVSE 420
M P P + P + P P S + +P++P P + GA +P DL+P +
Sbjct: 1384 MTP-----PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 421 PEEQAKEVTASMAP---PTIPSAT-PATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAES 476
K+ A+ AP P PS+ T P+ T P+ +E ++ +A +
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498
Query: 477 EKGGEEL---LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDA 533
G L +P +PA S + A T +S ++ L KEA+
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS----KKTPATLAPKEAL------ 1548
Query: 534 FKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKE 578
PPA + P P+ + P P+EA T SKE
Sbjct: 1549 -------------IPPAMTVPSPKK--TPAIPTPKEAPATPSSKE 1578
Score = 91.3 bits (225), Expect = 7e-18
Identities = 140/586 (23%), Positives = 200/586 (34%), Gaps = 61/586 (10%)
Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAA 63
+P G P P+ P P P +P TP A +P P A P +A
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992
Query: 64 SRVQSAAPARPGP-AAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122
PA P P A PA + S + P +GA P + P+
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 123 QPGAPGFYPGASPTEFG-----TYAGAYYPAQGVQQFPTG--VAPAPVLMNQPPQIAPKR 175
GAP P+ G + GA P P G P+P PP P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 176 ERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 235
+ + P G T + TPP G P A +P+ + P
Sbjct: 1113 PKG--GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 236 SQGAIIADRPGLPGPEHSPS-ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQ 294
+ A P G +PS + P++P+ TP PSP + LA S G T
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSP------KGGLATPSPKGAPTT--- 1220
Query: 295 MSVEESTPISRETG--EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQ-APTPL 351
+TP S + G P TP A P P P+ ++ P + APTP
Sbjct: 1221 ---PAATPPSPKGGLATPSPKGAPTTPAATP----------PSPKGGPATPPPKGAPTPP 1267
Query: 352 ASHTVEIHEPNGMVPSEDL-EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSP 410
A+ + P + P V + P PA P P A P +P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 411 PAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 470
P P P A + PT+P+ TP++ T+P+ +E + G
Sbjct: 1328 P-----PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 471 AGEAESEKGGEELLPPESTPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGD 529
A S K G + P+ P PA + + + A AT V +E + GD
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT----------REGAATPSKGD 1432
Query: 530 LLD------AFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEE 569
L + K+A PA + P S+ G + + PP P+E
Sbjct: 1433 LTPPAVTPVSLKKA-PATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Score = 80.1 bits (196), Expect = 2e-14
Identities = 153/651 (23%), Positives = 222/651 (34%), Gaps = 109/651 (16%)
Query: 11 PPAPSPGLPQPAFPPGQTAPVVFSTPQATQ------MNTPSQPRQHFYPSRAQPPSSAAS 64
PP+P GL A PP + AP +TP AT + TPS P+ A PPS
Sbjct: 1156 PPSPKGGL---ATPPPKGAP---TTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGG 1208
Query: 65 RVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQP 124
+ P A P+ + PS P + A P P + P P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSPKGGPATPPPKGAPTPP 1267
Query: 125 GA--PGFYPG-ASPTEFGTYAGAYY----PAQGVQQFPTGVAPAPVLMNQPPQIAPKRER 177
A P G A+P G A P G P AP P P +PK
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP---SPKGSP 1324
Query: 178 KTIRIRDPNQGGKD---ITEEIMSGARTASTPTPPQTGGGLEPQAN-GETPQVAVIVRPD 233
T P +G +T G T TP GG P + G TP A P
Sbjct: 1325 GT----PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---PS 1377
Query: 234 DRSQGAIIADRP----GLPGPEHSPSESQ--PSSPSPTPSPSPVLEPGSEPNLAVLSIPG 287
+ A+ P +P P+ P+ P SP P+ E + P+ L+ P
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437
Query: 288 DTMTTIQMSVEESTP-----ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 342
T +++ + S P G+P + P EP +V S ++ +
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 343 SPLQAPT---------------------PLASHTVEIHE--PNGMVPSEDLEPEVESSPE 379
+P+ APT P+A + + P + P E L P + P
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 380 LAPPPACPSESPVPIAPTAQPEE--------LLNGAPSPPAVDLSP-VSEPEEQAKEVTA 430
PA P+ P P+++ GAPSP + + P V+ P +
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP 1617
Query: 431 SMAPPTIPS--ATPATAPSATSPAQEEEMEEEEEEEEGE--------AGEAGEAESEKGG 480
++ PP+ ATPA + TSP ++ +A + K G
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
Query: 481 EELL-------PPESTPI---PANLSQNLEAAAATQVAVSV-PKRRRKIKELNKKEAVGD 529
L PESTPI P + ++AT + P + K A
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 530 LLDAFKEAN-PAVPEVENQPPAGSNPGPESEGS---------GVPPRPEEA 570
LL K+++ A + + P G PES+ S V P+PE A
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Score = 68.6 bits (166), Expect = 5e-11
Identities = 140/588 (23%), Positives = 196/588 (33%), Gaps = 83/588 (14%)
Query: 10 PPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSA 69
P PSP LP PPG T V + + S P++ P+ S+ AS +
Sbjct: 731 PKSVPSPSLPPAGTPPG-TKKVDGISHTSALAPVASSPKE--CPTEDSGASATASSKGTL 787
Query: 70 APARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGF 129
P+ P G V + P P +G+ G T + PV P F
Sbjct: 788 TYLADSPS----PLG--VSVSPQTKRPPTKKGS-----AGPDT-PIGNLSSPVSPVEASF 835
Query: 130 YP-------GASPTEFGTYAGAYYPAQGVQQFPTGVAP-APVLMNQPPQIAPKRERKTIR 181
P G+ + T++ +G P+ V P +P + PP+ P +
Sbjct: 836 LPENSLSFQGSKDSPATTHSPTPPSPKGAPT-PSAVTPLSPKGVTLPPKETP--TPSVVN 892
Query: 182 IRDPNQG-GKDITEEIMSGARTASTP-----TPPQTGGGLEPQANG-ETPQVAVIVRPDD 234
+ P +G ++ + + T+S+P TP G P G TP A P
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP-- 950
Query: 235 RSQGAIIADRPGLPGPEHSPSESQPSSPSP-----TPSPSPVLEPGSEPNLAVLSIPGDT 289
P P P+ +P+ + PSP TPSP P P S G
Sbjct: 951 -------KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP---PAATPPSPKGGP 1000
Query: 290 MTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT 349
T + P P SP+ +P A P + T P S SP P
Sbjct: 1001 AT----PSPKGAPTPPAVTPP---SPKGSPAATPFPKGASTPPAATPPSP-KGSPAATPL 1052
Query: 350 PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPS 409
P + T P +PS P S PPA SP T P+ GAP
Sbjct: 1053 PKGAPTT----PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK----GAPM 1104
Query: 410 PP-AVDLSP---VSEPEEQAKEVTASMAPP-------TIPSATPATAPSATSPAQEEEME 458
PP A SP ++ P + T + PP T P T P+AT P+ + +
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL- 1163
Query: 459 EEEEEEEGEAGEAGEAESEKGGEELLPPESTP-IPANLSQNLEAAAATQVAVSVPKRRRK 517
+ A S KGG P+ P PA + + AT PK
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT----PSPKGAPT 1219
Query: 518 IKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPP 565
G L + P P P G P +G+ PP
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Score = 63.5 bits (153), Expect = 2e-09
Identities = 136/642 (21%), Positives = 216/642 (33%), Gaps = 123/642 (19%)
Query: 21 PAFPPGQTAPVVFSTPQAT-QMNTPSQPRQHFYPSRAQPP----SSAASRVQSAAPARPG 75
P+F ++P + +P+AT + +P P+ + +S+AS +++ + A P
Sbjct: 571 PSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPD 630
Query: 76 PAAHVYPAGSQVMMIPSQISYP--ASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGA 133
A P ++ P+ ++P ++ A P + T T P G P
Sbjct: 631 SAG---PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN 687
Query: 134 SPTEFGTYAGAYYPAQGVQQFPTGVAP------------APVLMNQ------PPQIAPKR 175
P + GT + P +P AP + PP P
Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747
Query: 176 ERK------TIRIRDPNQGGKDITEEIMSGARTASTP--------TPPQTGGGLEPQ--- 218
+K T + K+ E + TAS+ +P G + PQ
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807
Query: 219 -------ANGETPQVAVIVRPDDRSQGAIIADRP-GLPGPEHSPSESQ-PSSPSPTPSPS 269
A +TP + + P + + + + G + SP+ + P+ PSP +P+
Sbjct: 808 PPTKKGSAGPDTP-IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 270 P-----------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 318
P L P P +V+++P + +++ +S + P + P
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 319 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 378
P P S SP APTP A+ T + PS P + P
Sbjct: 927 PKGIPA----------------SPSPKGAPTPPAA-TPPSPKGGPATPSPKWAP---TPP 966
Query: 379 ELAPP-----PACPSESPVPIAPTAQPEE--------LLNGAPSPPAVDL-----SPVSE 420
PP PA PS P P A P GAP+PPAV SP +
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 421 PEEQAKEVTASMAPPT---IPSATP-----ATAPSATSPAQEEEMEEEEEEEEGEAGEAG 472
P + + PP+ P+ATP T P+AT P+ + + A
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG-PATPSLKGAPTPPAA 1085
Query: 473 EAESEKGGEELLPPESTPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLL 531
S KGG P+ P+ PA + + AT P K G L
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK----GGLA 1141
Query: 532 DAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRPE 568
+ P P P G P +G + PP P+
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Score = 61.6 bits (148), Expect = 6e-09
Identities = 110/501 (21%), Positives = 161/501 (32%), Gaps = 98/501 (19%)
Query: 5 PQSTGPPPAPSPGLPQPA---FPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61
P +T P P SPG P P PP T P TP TPS PS + P+
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP-TLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 62 AASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVP-TQQY 120
A A P+ G A P+ + IPS P S IP + P T++
Sbjct: 1372 PA-----ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV--IPLSPKKAPATPVTREG 1424
Query: 121 PVQPGAPGFYPGA--------SPTEFGTYAGAYYPA-QGVQQFPTGVAPAPVLMNQPPQI 171
P P A +P G P+ +G P P+P P Q+
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 172 APKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVR 231
A K G + I S + TP + P A + + +
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA-TPSSRRDPIAPTATLLSKKTPATLA 1543
Query: 232 PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 291
P + A+I +P P+ +P+ P TPS P + P
Sbjct: 1544 PKE----ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599
Query: 292 TIQMSVEES-----------TPISRETGEPYRLSPEPTPLAEPILE-------------- 326
I +V TP S E G P +P+ TP + P+
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658
Query: 327 ----------------------VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGM 364
++ L P PE S+ + APT T
Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIITAPTRKGPQT--------- 1706
Query: 365 VPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQ 424
+ +SP + P P+ + S P++ T P LL P D S ++ ++
Sbjct: 1707 ------KKSSATSPPICPDPSAKNGSKGPLS-TVAPAPLL-----PVQKDSSKTAKGKDA 1754
Query: 425 AKEVTASMAPPTIPSATPATA 445
+ +APP ++TP TA
Sbjct: 1755 SHSPKGPLAPPESKASTPLTA 1775
Score = 43.5 bits (101), Expect = 0.002
Identities = 109/467 (23%), Positives = 167/467 (35%), Gaps = 82/467 (17%)
Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAAS 64
P S P AP+ L P AP P A M PS + P+ + P++ +S
Sbjct: 1520 PSSRRDPIAPTATLLSKK-TPATLAPKEALIPPA--MTVPSPKKTPAIPTPKEAPATPSS 1576
Query: 65 RVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPG-------QGRSTYV--- 114
+ S+ PA P+ + + ++IP ++ P+ + A P +G +T
Sbjct: 1577 KEASSPPAVT-PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Query: 115 VPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQG----VQQFPTG-----VAPAPV-- 163
PT PV P + P SP GA P ++ PT VAPAP
Sbjct: 1636 TPTSP-PVTPSSLKDSP-TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693
Query: 164 -LMNQPPQIAPKRERKTIR----IRDPN--QGGKDITEEIMSGARTASTPTPPQTGGGLE 216
++ P + P+ ++ + DP+ G K + +T G +
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
Query: 217 PQANGETPQVAVIVRPDDRSQGAIIAD--RPGLPGPEH-------SPSESQPSSPSPTPS 267
+ + P + P+ ++ + A LP PE SP S P +PSP P+
Sbjct: 1754 ASHSPKGP----LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
Query: 268 PSPVLE-PGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 326
P + S P L VL P + +E P+ + PEP P
Sbjct: 1810 LPPKQQFLPSSPGL-VLESPSKPLA--PADEDELLPL---------IPPEPISGGVPFQS 1857
Query: 327 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 386
V V + P S+ + PTP A V + S+ ES PEL
Sbjct: 1858 VLVNMPTP------KSAGIPVPTPSAKQPVTKNNKGSGTESD----SDESVPEL------ 1901
Query: 387 PSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 433
E T Q +L A +D PVS+ ++ E A A
Sbjct: 1902 --EEQDSTQATTQQAQLAAAA----EIDEEPVSKAKQSRSEKKARKA 1942
Score = 40.0 bits (92), Expect = 0.018
Identities = 110/520 (21%), Positives = 180/520 (34%), Gaps = 103/520 (19%)
Query: 6 QSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASR 65
++T PA LPQP +TA + P ++ ++ + Q P PP + +
Sbjct: 4 EATETVPATEQELPQPQ---AETAVL----PMSSALSVTAALGQ---PGPTLPPPCSPAP 53
Query: 66 VQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIP---GQGRSTYVVPTQQYPV 122
Q P A +P+ S + P ++ +P S +P T++ P+
Sbjct: 54 QQ--CPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI 111
Query: 123 QPGAPGFY-PGASPTEFGTYAGAYYPAQGVQQFPTGVAPA----PVLMNQPPQIAPKRER 177
P A P +PT GT + + P V P V + P L+ PP +A
Sbjct: 112 SPAALALASPMIAPTLKGTPSSSA-PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170
Query: 178 KTIRIR------DPNQGGKDITEEIMSGARTASTPTPP-----------------QTGGG 214
I + +P + E++ + TP+PP Q+G
Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVPNPK--GTPSPPCIVSTVPYHCVTPMASIQSGVA 228
Query: 215 LEPQANGETPQVAVIVRPDDRSQGAIIAD--RPG---LPGPEHSPS-------------E 256
PQ T + D + +++ PG L GP P+
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288
Query: 257 SQPSSPSPTPSPSPV-----LEPGSEPNLAVLSIPGDT-------MTTIQMSVEEST--- 301
SQ ++ TP P+ L P + + + + G T T +SV+ S+
Sbjct: 289 SQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348
Query: 302 --PISRETGEPYRLSPEPTPL---AEPILEVEVTLSKPVPES-------------EFSSS 343
P R P E P A P++ V S FS S
Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
Query: 344 PLQAPTPLASHTVEIHEP---NGMVPSEDLEPEVESSP-ELAPPPACPSESPVPIAPTAQ 399
P + +S H P V S P V ++P +A P E ++P
Sbjct: 409 PTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS 468
Query: 400 PEELLNGAP-SPPAVDLSPVSEPEEQAKEVTASMAPPTIP 438
+ N P SP A+ ++PV+ P+E + +V ++ P P
Sbjct: 469 SGPISNIEPTSPAALVMAPVA-PKEPSTQVATTLRIPVSP 507
Score = 38.9 bits (89), Expect = 0.040
Identities = 79/336 (23%), Positives = 117/336 (34%), Gaps = 53/336 (15%)
Query: 250 PEHSPS-ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR--- 305
P++SPS +S SSP SP L S + P +MT+ + V S + +
Sbjct: 567 PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS-PLGVNSSASVIKTDS 625
Query: 306 ----ETGEPYRLSP--EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH 359
++ P S PT A P+ + P S+ A +P TV +
Sbjct: 626 YAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA-SPFLEGTVSLA 684
Query: 360 EPNGMVPSEDLE--PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSP 417
N V L P V ++ E P P + P+A E+ PSP L P
Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP---SLPP 741
Query: 418 VSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESE 477
P K+V S T A AP A+SP +E E+ G + A S
Sbjct: 742 AGTP-PGTKKVDGI-------SHTSALAPVASSP------KECPTEDSGASATA----SS 783
Query: 478 KGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR---KIKELNKKEAVGDLLDAF 534
KG L +P+ ++S P+ +R K +G+L
Sbjct: 784 KGTLTYLADSPSPLGVSVS---------------PQTKRPPTKKGSAGPDTPIGNLSSPV 828
Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEA 570
+ + GS P + S PP P+ A
Sbjct: 829 SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 85.1 bits (209), Expect = 5e-16
Identities = 133/582 (22%), Positives = 202/582 (34%), Gaps = 100/582 (17%)
Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71
P+ GL +PA ++ S+P + + PR +PS+ +P A R P
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131
R A + P S + PS + SQ +P S+ + P+ P P
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS--P 345
Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD 191
A P+ +Q P+ PP P + T + P
Sbjct: 346 SAPPS--------------LQTLPS-----------PPATPP--SQATTSLGSPT---LQ 375
Query: 192 ITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPE 251
T + + TPP PQA P +A+ P L P
Sbjct: 376 ATHSFLPSPPLSPLATPP-------PQA---PPALAL----------------PPLQAPP 409
Query: 252 HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 311
SP S P SP TPSP A S P S S P+S P
Sbjct: 410 -SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP- 467
Query: 312 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 371
S P LA P L+V + P S ++ P QAP PLA+ +++ +P P
Sbjct: 468 --SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525
Query: 372 PEVESSPELAPPPACPSESP------VPIAPTAQP---------EELLNGAPSPPAVDL- 415
P +++ P +PP + P ++P +P++P A P LL PSPPA
Sbjct: 526 PPLQALP--SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583
Query: 416 -------SPVSEPEEQAKEVTASMA--PPTIPSATPATAPSATSPAQEEEMEEEEEEEEG 466
+P + +T ++A PP PS +P++ S A EE
Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE-- 641
Query: 467 EAGEAGEAESEKGGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELN 522
G +GG PP + PA S+ A + A P
Sbjct: 642 ---LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698
Query: 523 KKEAVGDLLDAF--KEANPAVPEVENQPPAGSNPGPESEGSG 562
+ + + + + A PA ++ P G++ G + G+G
Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 740
Score = 60.1 bits (144), Expect = 2e-08
Identities = 133/519 (25%), Positives = 175/519 (33%), Gaps = 90/519 (17%)
Query: 4 APQSTGPPPA----PSPGLPQPAFPPGQTAPVVFS-TPQATQMNTPSQPRQHF-YPSRAQ 57
AP S PP+ PSP PA PP Q + S T QAT PS P P
Sbjct: 341 APPSPSAPPSLQTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396
Query: 58 PPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPT 117
PP+ A +Q AP P + + P + P+ ++ Q + P P
Sbjct: 397 PPALALPPLQ--APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-------PP 447
Query: 118 QQYPVQPGA-PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRE 176
Q P P A P P A+P + A P Q V P P PPQ P
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 177 RKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRS 236
+++ P PPQ L TP + + P
Sbjct: 507 APPLQLAKP----------------------PPQAPPAL------ATPPLQALPSPP--- 535
Query: 237 QGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMS 296
A PG SPS S P SP TP P VL+ P +
Sbjct: 536 -----ASFPG--QAPFSPSASLPMSPLATPPPQAP---------PVLAAP-------LLQ 572
Query: 297 VEESTPISRETGEPYRLSPEPTP---LAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS 353
V S P S P R P P P ++ P L + + P P S SS L P LA
Sbjct: 573 VPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP-DLAG 630
Query: 354 HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL--NGAPSPP 411
H+ + D P E +PPP + P A + P L GAP P
Sbjct: 631 HSSSATSTPEELRGYDSGP--EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688
Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEA 471
+ P + P A + SATP AP A P + AG +
Sbjct: 689 -LPWPPATGP-GSADGLCTIYETEGPESATP--APGALDPGPSPGTSGGKAAAGAGAGAS 744
Query: 472 GEA--ESEKGGEELLPPESTPIPANLSQNLEAAAATQVA 508
+ ++ G L +++ + LS+ L AAA A
Sbjct: 745 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 783
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 84.0 bits (206), Expect = 1e-15
Identities = 177/796 (22%), Positives = 269/796 (33%), Gaps = 141/796 (17%)
Query: 9 GPPPAPSPG----LPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA-- 62
G PPA PG P PA PP Q P + P A Q T P Q P +PP+
Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPGTVKPPVQP--PGTTKPPAQPLG 367
Query: 63 -----ASRVQSAAPA--RPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---------P 106
A + S P+ +PGP A P G V P+Q PA + P
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425
Query: 107 GQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMN 166
G + PVQ PG P T A P + Q P P P
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP---- 481
Query: 167 QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226
Q P A ++ + P+Q + ST PPQ G +P +PQ
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQ-------------QPGSTKPPPQQPGPAKP-----SPQQ 523
Query: 227 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIP 286
+P + +PG P S + P+ PS S PV + GS
Sbjct: 524 PGSTKPPSQ--------QPGSAKP--SAQQPSPAKPSAQQSTKPVSQTGS---------- 563
Query: 287 GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT--LSKPVPESEFSSSP 344
P+ T P P L + I + T L VPE ++
Sbjct: 564 -------------GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 345 LQAPTPLAS--------HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES--PVPI 394
+ T + S H E+ E + + + + +LAP P+ P P+
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCL----NCQMKRALGGDLAPVPSSPQPKLKTAPV 666
Query: 395 APTA-------QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM--APPTIPSATPATA 445
T+ QP++ + P DLS EP++ V P+ + P A
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 446 PSATSPAQEEEMEEEEEEEEGEAGEAGEAESE--KGGEELLPPESTPIPANLSQNLEAAA 503
S + PA +E E+++ + + + K +L+ S ++ + +
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 504 ATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGV 563
A + + P + K G+ + F + A+P + S+PGP SE G
Sbjct: 787 AEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASDSKIISHPGPSSESKG- 842
Query: 564 PPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFI 623
+ D + E + + K K D KP+ G Q +
Sbjct: 843 -----------QKQVDPVQKKEEPKKAQTKMSPKPDA-KPMPKGSPTPPGPRPTAG-QTV 889
Query: 624 FASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGP--DFTPSFANLGRTTLSTR 681
Q P+ L+ + T PT Q G F S + +ST
Sbjct: 890 PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA 949
Query: 682 GPP----RGGPGGELPRGPAGLGPRRSQQGPR---KEPRKIIATVLMTEDIKLNKAEK-- 732
G P + GPG + + PA P SQ P+ + P ++ + ++ K AEK
Sbjct: 950 GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE 1009
Query: 733 ---AWKPSSKRTAADK 745
P+ KRT +K
Sbjct: 1010 PKAEQAPTVKRTETEK 1025
Score = 65.5 bits (158), Expect = 4e-10
Identities = 129/619 (20%), Positives = 208/619 (33%), Gaps = 109/619 (17%)
Query: 5 PQSTGP--PPAPSPGLPQP-AFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61
PQ GP PP PG +P + PG T P PQ PS + +Q P S
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKP----PPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 62 AASRVQSAAPARPGPAAHVYP---AGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVP-- 116
A Q +PA+P P GS + P +S A Q P QG + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP----PSQGLPKTICPLC 592
Query: 117 ------------------TQQYPVQPGAPGFYPGASPTEFGTYA---GAYYPAQGVQQFP 155
T+ GF P TE + A G P
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652
Query: 156 TGVAPAPVLMN--------------QPPQIAPKRE----RKTIRIRDPNQGGKDITEEIM 197
+P P L QP Q +PK++ + + +P + + + +
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 198 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 257
G+ +A PP+ L A + P V P ++ + + D+P P P+
Sbjct: 713 HGSPSAKAKQPPE-ADSLSKPAPPKEPSV-----PSEQDKAPVADDKPKQP-KMVKPTTD 765
Query: 258 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST--PISRETGEPYRLSP 315
SS S T P IP + +Q EE T P+ ++ +P + P
Sbjct: 766 LVSSSSATTKP---------------DIPS---SKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 316 EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 375
P E + + SK +P S + P P + E + P + E +
Sbjct: 808 ---PTGEKVSPFD---SKAIPRPASDSKIISHPGP----SSESKGQKQVDPVQKKEEPKK 857
Query: 376 SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP 435
+ +++P P P+P P + P SP +P+EQ++ + ++
Sbjct: 858 AQTKMSPK---PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP--KPQEQSRRFSLNLGSI 912
Query: 436 TIPSATPATAPSATSPAQ----EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 491
T + T P T + + + AG+ G G P + P
Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG---APMKQAPA 969
Query: 492 PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAG 551
P+ + +T A P + +K+ K A + L+ E P V E +
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPA-AEKLEPKAEQAPTVKRTETE---- 1024
Query: 552 SNPGPESEGSGVPPRPEEA 570
P P + + P++A
Sbjct: 1025 KKPPPIKDSKSLTAEPQKA 1043
Score = 63.9 bits (154), Expect = 1e-09
Identities = 98/404 (24%), Positives = 148/404 (36%), Gaps = 88/404 (21%)
Query: 149 QGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP 208
Q Q P G+ P L QPP+ PK++ RDP Q +D T + +S + +
Sbjct: 197 QKEQGKPEGIIKPP-LQQQPPKPIPKQQGPG---RDPLQ--QDGTPKSISSQQPEKIKSQ 250
Query: 209 PQTGGGLEPQANGETPQVAVIVRPDDRS-------QGAIIAD---RPGLPGPEHSPSESQ 258
P G G Q +TPQ P R Q I+ +P LP P S+
Sbjct: 251 PP-GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP------SK 303
Query: 259 PSSPSPTPSPSPVLEPG---SEPNLA------------VLSIPGDTMTTIQ--------- 294
P PTP P +PG S+P A + PG +Q
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 295 MSVEESTPISRETG--EPYRLSPEPTPLAEP---------------ILEVEVTLSKPVPE 337
+ + P +++TG +P P P LA+P +V KP+ +
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 338 SEFSSSPLQAPTPLASHTVEIHEPN-GMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 396
SP +AP P + + +P G +P++ P S+ + P PS+ P P P
Sbjct: 424 QPGLQSPAKAPGPTKT---PVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPAKP 479
Query: 397 ------TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP---TIPSATPATA-P 446
A+P G+ PP+ P +Q S P PS P +A P
Sbjct: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539
Query: 447 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 490
SA P+ + ++ + + G G+ L PP +P
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTG---------SGKPLQPPTVSP 574
Score = 61.6 bits (148), Expect = 6e-09
Identities = 132/615 (21%), Positives = 206/615 (33%), Gaps = 97/615 (15%)
Query: 6 QSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASR 65
Q TGP PS LP PA PP Q PQ QP PS Q P S
Sbjct: 462 QQTGPTKPPSQ-LPGPAKPPPQQPGPAKPPPQ--------QPGSAKPPS--QQPGSTKPP 510
Query: 66 VQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPG 125
Q PA+P P P P+ Q PG + P+ Q P P
Sbjct: 511 PQQPGPAKPSPQQ------------PGSTKPPSQQ-----PGSAK-----PSAQQP-SPA 547
Query: 126 APGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 185
P P + G+ P Q P+ A P P I P + + P
Sbjct: 548 KPSAQQSTKPV---SQTGSGKPLQPPTVSPS--AKQPPSQGLPKTICPLCNTTELLLHVP 602
Query: 186 NQGGKDITEEIMSG--ARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 243
+ + E + + P P T E + + R+ G +A
Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLT----------EVKEWLCLNCQMKRALGGDLAP 652
Query: 244 RPGLPGPE------HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV 297
P P P+ + S SSP P + SP + + +L+ P ++
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQT-SPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
Query: 298 EESTPISRETGEPYRLS-PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV 356
+P ++ P S +P P EP + E + + ++ T L S +
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771
Query: 357 EIHEPNGMVPSEDLEPEVE--SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVD 414
+P+ +PS ++ + E ++P L A PS+S P P + + A PA D
Sbjct: 772 ATTKPD--IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASD 827
Query: 415 LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQE-EEMEEEEEEEEGEAGEAGE 473
+S P ++ P P A + SP + + M + G AG+
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 474 AESEKGGEELLPPESTPIPANLSQ--NLEAAAATQVAVSVPKRRRK-------------I 518
+ P+ +P P S+ +L + T S P ++
Sbjct: 888 T--------VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939
Query: 519 KELNKKEAVGDLLDAFKEANPAVP----EVENQPPAGSNPGPESEGSGVPPRPEEADETW 574
+ + + ++ P P +QPP P P+S G PP P ++
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP-PKSTGQ-APPAPAKSIPV- 996
Query: 575 DSKEDKIHNAENIQP 589
KE K AE ++P
Sbjct: 997 -KKETKAPAAEKLEP 1010
Score = 58.2 bits (139), Expect = 6e-08
Identities = 142/692 (20%), Positives = 239/692 (34%), Gaps = 132/692 (19%)
Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
++KAP+ PPP + QP G + P+A ++ P+ P++ PS
Sbjct: 694 LSKAPEPKKPPPL----VKQPTLH-GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748
Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120
A + + +P + + IPS S SQ ++ P+Q +
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 121 P-----VQPGAPGFYP-GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPP----- 169
P V P P AS ++ ++ G ++G +Q PV + P
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD------PVQKKEEPKKAQT 860
Query: 170 QIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLE------------- 216
+++PK + K + P G T + PTP Q+ E
Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPT-------AGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 217 --PQANGETPQVAVIVR-----PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269
P++ TPQ V + SQ + + G PGP P +P PS
Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973
Query: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329
P + P + + +S P+ +ET P EP P ++
Sbjct: 974 PTSQG-----------PPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 330 TLSKPVP---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 386
T KP P ++ P +A P E + +L + P C
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
Query: 387 PSE-------SPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPS 439
++ +P P Q E L + A+ Q ++ P+ P
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQ-EWLCLNCQTQRAI--------SGQLGDIRKMPPAPSGPK 1133
Query: 440 ATPATAPSATS------PAQEEEMEEEEEEEEGEAGEA-GEAESEKGGEELLPPESTPIP 492
A+P P+ +S P Q + ++++E+E + EA + E E E +PP T
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 493 ANLSQNLE--AAAATQVAVSVPKRRRKIKELNK--KEAVGDLLDAFK---EANPAVPEVE 545
LE A+A Q +P+ ++ I E K E LL+ K E +PE +
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253
Query: 546 NQPP-----------------------------AGSNPGPESEG--SGVPPR-PEEADET 573
P G P + EG SG P P+E D+T
Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKT 1313
Query: 574 WDSKEDK-----IHNAENIQPGEQKYEYKSDQ 600
+ +++ + ++PG++K E + D+
Sbjct: 1314 TKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDK 1345
Score = 42.0 bits (97), Expect = 0.005
Identities = 60/236 (25%), Positives = 85/236 (36%), Gaps = 40/236 (16%)
Query: 231 RPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP-----SPSPVLEPGSEPNLAVLSI 285
RP RS I+ +P P P P P P P P SP P + P + L V S
Sbjct: 2391 RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILP--KKKLTVAS- 2447
Query: 286 PGDTMTTI--QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSS 343
P T T + ++ E+T + R G P+ + T PVP
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNG-------------LPVTRICTTAPPPVPPK----- 2489
Query: 344 PLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE-E 402
P+ + S V H P P +P + P P P ++ T+
Sbjct: 2490 ----PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLN 2545
Query: 403 LLNGA----PSPPAVDLSPVSEPEEQ--AKEVTASMAPPTIPSATPATAPSATSPA 452
L+ A PSP + LSP S +K +T + T+PS S+ S A
Sbjct: 2546 LVTSADYKLPSPTS-PLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQA 2600
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 84.0 bits (206), Expect = 1e-15
Identities = 177/796 (22%), Positives = 269/796 (33%), Gaps = 141/796 (17%)
Query: 9 GPPPAPSPG----LPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA-- 62
G PPA PG P PA PP Q P + P A Q T P Q P +PP+
Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPGTVKPPVQP--PGTTKPPAQPLG 367
Query: 63 -----ASRVQSAAPA--RPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---------P 106
A + S P+ +PGP A P G V P+Q PA + P
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425
Query: 107 GQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMN 166
G + PVQ PG P T A P + Q P P P
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP---- 481
Query: 167 QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226
Q P A ++ + P+Q + ST PPQ G +P +PQ
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQ-------------QPGSTKPPPQQPGPAKP-----SPQQ 523
Query: 227 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIP 286
+P + +PG P S + P+ PS S PV + GS
Sbjct: 524 PGSTKPPSQ--------QPGSAKP--SAQQPSPAKPSAQQSTKPVSQTGS---------- 563
Query: 287 GDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT--LSKPVPESEFSSSP 344
P+ T P P L + I + T L VPE ++
Sbjct: 564 -------------GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 345 LQAPTPLAS--------HTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES--PVPI 394
+ T + S H E+ E + + + + +LAP P+ P P+
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCL----NCQMKRALGGDLAPVPSSPQPKLKTAPV 666
Query: 395 APTA-------QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM--APPTIPSATPATA 445
T+ QP++ + P DLS EP++ V P+ + P A
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
Query: 446 PSATSPAQEEEMEEEEEEEEGEAGEAGEAESE--KGGEELLPPESTPIPANLSQNLEAAA 503
S + PA +E E+++ + + + K +L+ S ++ + +
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 504 ATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGV 563
A + + P + K G+ + F + A+P + S+PGP SE G
Sbjct: 787 AEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASDSKIISHPGPSSESKG- 842
Query: 564 PPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFI 623
+ D + E + + K K D KP+ G Q +
Sbjct: 843 -----------QKQVDPVQKKEEPKKAQTKMSPKPDA-KPMPKGSPTPPGPRPTAG-QTV 889
Query: 624 FASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGP--DFTPSFANLGRTTLSTR 681
Q P+ L+ + T PT Q G F S + +ST
Sbjct: 890 PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA 949
Query: 682 GPP----RGGPGGELPRGPAGLGPRRSQQGPR---KEPRKIIATVLMTEDIKLNKAEK-- 732
G P + GPG + + PA P SQ P+ + P ++ + ++ K AEK
Sbjct: 950 GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE 1009
Query: 733 ---AWKPSSKRTAADK 745
P+ KRT +K
Sbjct: 1010 PKAEQAPTVKRTETEK 1025
Score = 65.5 bits (158), Expect = 4e-10
Identities = 129/619 (20%), Positives = 208/619 (33%), Gaps = 109/619 (17%)
Query: 5 PQSTGP--PPAPSPGLPQP-AFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61
PQ GP PP PG +P + PG T P PQ PS + +Q P S
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKP----PPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 62 AASRVQSAAPARPGPAAHVYP---AGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVP-- 116
A Q +PA+P P GS + P +S A Q P QG + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP----PSQGLPKTICPLC 592
Query: 117 ------------------TQQYPVQPGAPGFYPGASPTEFGTYA---GAYYPAQGVQQFP 155
T+ GF P TE + A G P
Sbjct: 593 NTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP 652
Query: 156 TGVAPAPVLMN--------------QPPQIAPKRE----RKTIRIRDPNQGGKDITEEIM 197
+P P L QP Q +PK++ + + +P + + + +
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 198 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 257
G+ +A PP+ L A + P V P ++ + + D+P P P+
Sbjct: 713 HGSPSAKAKQPPE-ADSLSKPAPPKEPSV-----PSEQDKAPVADDKPKQP-KMVKPTTD 765
Query: 258 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST--PISRETGEPYRLSP 315
SS S T P IP + +Q EE T P+ ++ +P + P
Sbjct: 766 LVSSSSATTKP---------------DIPS---SKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 316 EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 375
P E + + SK +P S + P P + E + P + E +
Sbjct: 808 ---PTGEKVSPFD---SKAIPRPASDSKIISHPGP----SSESKGQKQVDPVQKKEEPKK 857
Query: 376 SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP 435
+ +++P P P+P P + P SP +P+EQ++ + ++
Sbjct: 858 AQTKMSPK---PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP--KPQEQSRRFSLNLGSI 912
Query: 436 TIPSATPATAPSATSPAQ----EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 491
T + T P T + + + AG+ G G P + P
Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG---APMKQAPA 969
Query: 492 PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAG 551
P+ + +T A P + +K+ K A + L+ E P V E +
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPA-AEKLEPKAEQAPTVKRTETE---- 1024
Query: 552 SNPGPESEGSGVPPRPEEA 570
P P + + P++A
Sbjct: 1025 KKPPPIKDSKSLTAEPQKA 1043
Score = 63.9 bits (154), Expect = 1e-09
Identities = 98/404 (24%), Positives = 148/404 (36%), Gaps = 88/404 (21%)
Query: 149 QGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP 208
Q Q P G+ P L QPP+ PK++ RDP Q +D T + +S + +
Sbjct: 197 QKEQGKPEGIIKPP-LQQQPPKPIPKQQGPG---RDPLQ--QDGTPKSISSQQPEKIKSQ 250
Query: 209 PQTGGGLEPQANGETPQVAVIVRPDDRS-------QGAIIAD---RPGLPGPEHSPSESQ 258
P G G Q +TPQ P R Q I+ +P LP P S+
Sbjct: 251 PP-GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP------SK 303
Query: 259 PSSPSPTPSPSPVLEPG---SEPNLA------------VLSIPGDTMTTIQ--------- 294
P PTP P +PG S+P A + PG +Q
Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 295 MSVEESTPISRETG--EPYRLSPEPTPLAEP---------------ILEVEVTLSKPVPE 337
+ + P +++TG +P P P LA+P +V KP+ +
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 338 SEFSSSPLQAPTPLASHTVEIHEPN-GMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 396
SP +AP P + + +P G +P++ P S+ + P PS+ P P P
Sbjct: 424 QPGLQSPAKAPGPTKT---PVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-PSQLPGPAKP 479
Query: 397 ------TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP---TIPSATPATA-P 446
A+P G+ PP+ P +Q S P PS P +A P
Sbjct: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP 539
Query: 447 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 490
SA P+ + ++ + + G G+ L PP +P
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTG---------SGKPLQPPTVSP 574
Score = 61.6 bits (148), Expect = 6e-09
Identities = 132/615 (21%), Positives = 206/615 (33%), Gaps = 97/615 (15%)
Query: 6 QSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASR 65
Q TGP PS LP PA PP Q PQ QP PS Q P S
Sbjct: 462 QQTGPTKPPSQ-LPGPAKPPPQQPGPAKPPPQ--------QPGSAKPPS--QQPGSTKPP 510
Query: 66 VQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPG 125
Q PA+P P P P+ Q PG + P+ Q P P
Sbjct: 511 PQQPGPAKPSPQQ------------PGSTKPPSQQ-----PGSAK-----PSAQQP-SPA 547
Query: 126 APGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 185
P P + G+ P Q P+ A P P I P + + P
Sbjct: 548 KPSAQQSTKPV---SQTGSGKPLQPPTVSPS--AKQPPSQGLPKTICPLCNTTELLLHVP 602
Query: 186 NQGGKDITEEIMSG--ARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIAD 243
+ + E + + P P T E + + R+ G +A
Sbjct: 603 EKANFNTCTECQTTVCSLCGFNPNPHLT----------EVKEWLCLNCQMKRALGGDLAP 652
Query: 244 RPGLPGPE------HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV 297
P P P+ + S SSP P + SP + + +L+ P ++
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQT-SPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
Query: 298 EESTPISRETGEPYRLS-PEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV 356
+P ++ P S +P P EP + E + + ++ T L S +
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771
Query: 357 EIHEPNGMVPSEDLEPEVE--SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVD 414
+P+ +PS ++ + E ++P L A PS+S P P + + A PA D
Sbjct: 772 ATTKPD--IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD--SKAIPRPASD 827
Query: 415 LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQE-EEMEEEEEEEEGEAGEAGE 473
+S P ++ P P A + SP + + M + G AG+
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 474 AESEKGGEELLPPESTPIPANLSQ--NLEAAAATQVAVSVPKRRRK-------------I 518
+ P+ +P P S+ +L + T S P ++
Sbjct: 888 T--------VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939
Query: 519 KELNKKEAVGDLLDAFKEANPAVP----EVENQPPAGSNPGPESEGSGVPPRPEEADETW 574
+ + + ++ P P +QPP P P+S G PP P ++
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP-PKSTGQ-APPAPAKSIPV- 996
Query: 575 DSKEDKIHNAENIQP 589
KE K AE ++P
Sbjct: 997 -KKETKAPAAEKLEP 1010
Score = 58.2 bits (139), Expect = 6e-08
Identities = 142/692 (20%), Positives = 239/692 (34%), Gaps = 132/692 (19%)
Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
++KAP+ PPP + QP G + P+A ++ P+ P++ PS
Sbjct: 694 LSKAPEPKKPPPL----VKQPTLH-GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748
Query: 61 SAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQY 120
A + + +P + + IPS S SQ ++ P+Q +
Sbjct: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSF 806
Query: 121 P-----VQPGAPGFYP-GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPP----- 169
P V P P AS ++ ++ G ++G +Q PV + P
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD------PVQKKEEPKKAQT 860
Query: 170 QIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLE------------- 216
+++PK + K + P G T + PTP Q+ E
Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPT-------AGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
Query: 217 --PQANGETPQVAVIVR-----PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269
P++ TPQ V + SQ + + G PGP P +P PS
Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973
Query: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329
P + P + + +S P+ +ET P EP P ++
Sbjct: 974 PTSQG-----------PPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
Query: 330 TLSKPVP---ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPAC 386
T KP P ++ P +A P E + +L + P C
Sbjct: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
Query: 387 PSE-------SPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPS 439
++ +P P Q E L + A+ Q ++ P+ P
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQ-EWLCLNCQTQRAI--------SGQLGDIRKMPPAPSGPK 1133
Query: 440 ATPATAPSATS------PAQEEEMEEEEEEEEGEAGEA-GEAESEKGGEELLPPESTPIP 492
A+P P+ +S P Q + ++++E+E + EA + E E E +PP T
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 493 ANLSQNLE--AAAATQVAVSVPKRRRKIKELNK--KEAVGDLLDAFK---EANPAVPEVE 545
LE A+A Q +P+ ++ I E K E LL+ K E +PE +
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253
Query: 546 NQPP-----------------------------AGSNPGPESEG--SGVPPR-PEEADET 573
P G P + EG SG P P+E D+T
Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKT 1313
Query: 574 WDSKEDK-----IHNAENIQPGEQKYEYKSDQ 600
+ +++ + ++PG++K E + D+
Sbjct: 1314 TKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDK 1345
Score = 42.0 bits (97), Expect = 0.005
Identities = 60/236 (25%), Positives = 85/236 (36%), Gaps = 40/236 (16%)
Query: 231 RPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP-----SPSPVLEPGSEPNLAVLSI 285
RP RS I+ +P P P P P P P P SP P + P + L V S
Sbjct: 2391 RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILP--KKKLTVAS- 2447
Query: 286 PGDTMTTI--QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSS 343
P T T + ++ E+T + R G P+ + T PVP
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNG-------------LPVTRICTTAPPPVPPK----- 2489
Query: 344 PLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE-E 402
P+ + S V H P P +P + P P P ++ T+
Sbjct: 2490 ----PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLN 2545
Query: 403 LLNGA----PSPPAVDLSPVSEPEEQ--AKEVTASMAPPTIPSATPATAPSATSPA 452
L+ A PSP + LSP S +K +T + T+PS S+ S A
Sbjct: 2546 LVTSADYKLPSPTS-PLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQA 2600
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 83.6 bits (205), Expect = 1e-15
Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59
KA +T P +P P P +TP+ TP +P P+ + P
Sbjct: 200 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118
+ ++ P P P PA + P+ PA P +S P +
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 300
Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178
P P P P T P + PT PAP +P APK+
Sbjct: 301 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238
T P + +E +PT P+ P P P
Sbjct: 359 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 411
Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298
P P P+ + P P+PT P EP P T T
Sbjct: 412 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 463
Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
P EP +P+ T P T K P + +P P LA T E
Sbjct: 464 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 520
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418
EP P E P P A +P APT P+E P PA
Sbjct: 521 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 564
Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478
+ P+E A AP T+ P T PA +E +E + + K
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534
G P E P PA + A + ++ KEL G
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681
Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573
+ P P+ E P P P + P PE T
Sbjct: 682 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 719
Score = 81.3 bits (199), Expect = 7e-15
Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
K+ +T PAP+ P P + AP P T TP +P P+ + P+
Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 289
Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122
++ P P P PA P+ PA +T PT P
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 331
Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179
+P P + + PA + P T PAP +P PK T
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391
Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239
P + S T P+P T P P + A
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451
Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293
+ P P+ + P P+PT P+ L P + LA + TT
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 510
Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351
EE P + E EP +PE P T +P P + +P + P P
Sbjct: 511 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411
P G P+ EP + + AP P+ + P + T P+P
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 618
Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469
+ + P+E A AP T P T P+ T+P + E +G
Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678
Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524
+ + +E P P T E T VS P ++ ++K
Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 738
Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580
E+ +L A P +EN P PG + + +PE D ++
Sbjct: 739 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 788
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 79 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 118
Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 119 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 172
Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 173 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 232
Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415
++S+P PA + P P T +P P+P P
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292
Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468
S + P+E A AP PT P T P +P +E +E A
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 352
Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519
+ + K P E P P + +A T P +
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 413 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 83.6 bits (205), Expect = 1e-15
Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59
KA +T P +P P P +TP+ TP +P P+ + P
Sbjct: 241 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118
+ ++ P P P PA + P+ PA P +S P +
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 341
Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178
P P P P T P + PT PAP +P APK+
Sbjct: 342 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238
T P + +E +PT P+ P P P
Sbjct: 400 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 452
Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298
P P P+ + P P+PT P EP P T T
Sbjct: 453 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 504
Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
P EP +P+ T P T K P + +P P LA T E
Sbjct: 505 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 561
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418
EP P E P P A +P APT P+E P PA
Sbjct: 562 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 605
Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478
+ P+E A AP T+ P T PA +E +E + + K
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534
G P E P PA + A + ++ KEL G
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722
Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573
+ P P+ E P P P + P PE T
Sbjct: 723 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 760
Score = 81.3 bits (199), Expect = 7e-15
Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
K+ +T PAP+ P P + AP P T TP +P P+ + P+
Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 330
Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122
++ P P P PA P+ PA +T PT P
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 372
Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179
+P P + + PA + P T PAP +P PK T
Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 432
Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239
P + S T P+P T P P + A
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492
Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293
+ P P+ + P P+PT P+ L P + LA + TT
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 551
Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351
EE P + E EP +PE P T +P P + +P + P P
Sbjct: 552 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411
P G P+ EP + + AP P+ + P + T P+P
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 659
Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469
+ + P+E A AP T P T P+ T+P + E +G
Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719
Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524
+ + +E P P T E T VS P ++ ++K
Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 779
Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580
E+ +L A P +EN P PG + + +PE D ++
Sbjct: 780 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 829
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 120 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 159
Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 160 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 213
Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 214 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 273
Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415
++S+P PA + P P T +P P+P P
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333
Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468
S + P+E A AP PT P T P +P +E +E A
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 393
Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519
+ + K P E P P + +A T P +
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 454 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 83.6 bits (205), Expect = 1e-15
Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59
KA +T P +P P P +TP+ TP +P P+ + P
Sbjct: 293 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118
+ ++ P P P PA + P+ PA P +S P +
Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 393
Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178
P P P P T P + PT PAP +P APK+
Sbjct: 394 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238
T P + +E +PT P+ P P P
Sbjct: 452 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 504
Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298
P P P+ + P P+PT P EP P T T
Sbjct: 505 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 556
Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
P EP +P+ T P T K P + +P P LA T E
Sbjct: 557 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 613
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418
EP P E P P A +P APT P+E P PA
Sbjct: 614 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 657
Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478
+ P+E A AP T+ P T PA +E +E + + K
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534
G P E P PA + A + ++ KEL G
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774
Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573
+ P P+ E P P P + P PE T
Sbjct: 775 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 812
Score = 81.3 bits (199), Expect = 7e-15
Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
K+ +T PAP+ P P + AP P T TP +P P+ + P+
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 382
Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122
++ P P P PA P+ PA +T PT P
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 424
Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179
+P P + + PA + P T PAP +P PK T
Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 484
Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239
P + S T P+P T P P + A
Sbjct: 485 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544
Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293
+ P P+ + P P+PT P+ L P + LA + TT
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 603
Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351
EE P + E EP +PE P T +P P + +P + P P
Sbjct: 604 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658
Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411
P G P+ EP + + AP P+ + P + T P+P
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 711
Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469
+ + P+E A AP T P T P+ T+P + E +G
Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 771
Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524
+ + +E P P T E T VS P ++ ++K
Sbjct: 772 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 831
Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580
E+ +L A P +EN P PG + + +PE D ++
Sbjct: 832 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 881
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 172 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 211
Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 212 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 265
Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 266 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 325
Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415
++S+P PA + P P T +P P+P P
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468
S + P+E A AP PT P T P +P +E +E A
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 445
Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519
+ + K P E P P + +A T P +
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 506 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 83.6 bits (205), Expect = 1e-15
Identities = 127/579 (21%), Positives = 171/579 (29%), Gaps = 67/579 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQ---HFYPSRAQPP 59
KA +T P +P P P +TP+ TP +P P+ + P
Sbjct: 334 KAETTTKGPALTTPKEPTP------------TTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118
+ ++ P P P PA + P+ PA P +S P +
Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA-------PTTTKSAPTTPKE 434
Query: 119 QYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERK 178
P P P P T P + PT PAP +P APK+
Sbjct: 435 PAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 179 TIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG 238
T P + +E +PT P+ P P P
Sbjct: 493 T----TPKEPAPTTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSA 545
Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298
P P P+ + P P+PT P EP P T T
Sbjct: 546 PTTPKEPS-PTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT------- 597
Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
P EP +P+ T P T K P + +P P LA T E
Sbjct: 598 -KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP-TTPEELAPTTPE- 654
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418
EP P E P P A +P APT P+E P PA
Sbjct: 655 -EPTPTTPEE---------PAPTTPKAAAPNTPKEPAPTT-PKEPAPTTPKEPA-----P 698
Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEK 478
+ P+E A AP T+ P T PA +E +E + + K
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 479 GGEELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 534
G P E P PA + A + ++ KEL G
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815
Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADET 573
+ P P+ E P P P + P PE T
Sbjct: 816 DKPAPTTPK-ETAPTTPKEPAPTTPKKPAPTTPETPPPT 853
Score = 81.3 bits (199), Expect = 7e-15
Identities = 125/598 (20%), Positives = 187/598 (31%), Gaps = 67/598 (11%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
K+ +T PAP+ P P + AP P T TP +P P+ + P+
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPK-EPAPTTTKEPAPT---TPKEPA----PTTTKEPAPT 423
Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122
++ P P P PA P+ PA +T PT P
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAP-----------TTPKEPTPTTPK 465
Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFP---TGVAPAPVLMNQPPQIAPKRERKT 179
+P P + + PA + P T PAP +P PK T
Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 525
Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 239
P + S T P+P T P P + A
Sbjct: 526 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585
Query: 240 IIADRPGLPGPEHSPSESQPSSPSPT------PSPSPVLEPGSEPNLAVLSIPGDTMTTI 293
+ P P+ + P P+PT P+ L P + LA + TT
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT- 644
Query: 294 QMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL--QAPTPL 351
EE P + E EP +PE P T +P P + +P + P P
Sbjct: 645 ---PEELAPTTPE--EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699
Query: 352 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 411
P G P+ EP + + AP P+ + P + T P+P
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD-------KPAPT 752
Query: 412 AVDLSPVSEPEEQAKEVTASMAPPTIPSATPAT--APSATSPAQEEEMEEEEEEEEGEAG 469
+ + P+E A AP T P T P+ T+P + E +G
Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 812
Query: 470 EAGEAESEKGGEELLP-----PESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524
+ + +E P P T E T VS P ++ ++K
Sbjct: 813 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 872
Query: 525 --EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDK 580
E+ +L A P +EN P PG + + +PE D ++
Sbjct: 873 PDESTPEL-----SAEPTPKALENSP---KEPGVPTTKTPAATKPEMTTTAKDKTTER 922
Score = 58.9 bits (141), Expect = 4e-08
Identities = 89/418 (21%), Positives = 139/418 (33%), Gaps = 76/418 (18%)
Query: 205 TPTPP---QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 261
TP PP + G GL+ NG+ + PD + +H+ + P
Sbjct: 213 TPKPPVVDEAGSGLD---NGDFK----VTTPDTSTT-------------QHNKVSTSPKI 252
Query: 262 PSPTP-SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPL 320
+ P +P P L P S+ + S+ + TT++ +E+T +++T + E T
Sbjct: 253 TTAKPINPRPSLPPNSDTSKET-SLTVNKETTVE--TKETTTTNKQTSTDGK---EKTTS 306
Query: 321 AEPILEVEVT-----------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369
A+ +E T L+KP P++E ++ TP EP P E
Sbjct: 307 AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 366
Query: 370 LEPEVESSPELAPPPACPSESPVPIAP-------TAQPEELLNGAPSP-------PAVDL 415
++S+P PA + P P T +P P+P P
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 416 SPVSEPEEQAKEVTASMAP-------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEA 468
S + P+E A AP PT P T P +P +E +E A
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA 486
Query: 469 GEAGEAESEKGGEELLPPESTP---------IPANLSQNLEAAAATQVAVSVPKRRRKIK 519
+ + K P E P P + +A T P +
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 520 ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSK 577
K+ + KE P P+ E P P P + P P+E T K
Sbjct: 547 TTPKEPSP----TTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 83.2 bits (204), Expect = 2e-15
Identities = 130/519 (25%), Positives = 192/519 (36%), Gaps = 69/519 (13%)
Query: 1 MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60
+ ++P S PSP L P PP + +P+ +P + +P P P+ P +
Sbjct: 515 LEESPLSPPEESPPSPALETPLSPPPEASPL---SPPFEE--SPLSPPPEELPTSPPPEA 569
Query: 61 SAASRVQSAAPARPGP----------AAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGR 110
S S +P P P A+ ++P + + P P S P
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS------PPPEA 623
Query: 111 STYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQ 170
S P + P+ P P P + P E + P V + +P ++ PP+
Sbjct: 624 SRLSPPPEDSPMSP-PPEESPMSPPPEVSRLS----PLPVVSRLSPPPEESP--LSPPPE 676
Query: 171 IAPKRER-KTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVI 229
+P + R+ P E+ + +P P L E+P + +
Sbjct: 677 ESPTSPPPEASRLSPP-------PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 230 VRPD--DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPG 287
P RS+G ++ RP P P E S + P SP E EP L ++P
Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE---EPCLC--AVPE 784
Query: 288 DTMTTIQMSVEESTP------ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFS 341
+ + Q +P +S +T EP+ LSP P EP L + S P+SE
Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTEEPH-LSPVPE---EPCLSPQPEESHLSPQSE-- 838
Query: 342 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES---SPE---LAPPPACPSESPVPIA 395
P +P P SH E + P + PE +PE L PPP PS SP+
Sbjct: 839 -EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 396 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEE 455
P +P P + LSP EP + + PP + A AP A SP E
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 456 EMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPAN 494
E G G++ + ES L P S P AN
Sbjct: 958 EY------PFGAKGDS-DPESPLAAPILETPISPPPEAN 989
Score = 75.5 bits (184), Expect = 4e-13
Identities = 104/403 (25%), Positives = 146/403 (36%), Gaps = 69/403 (17%)
Query: 187 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 246
QGG+ I S +PP+ G + P + G + + +P
Sbjct: 353 QGGQTIRSVAEQHTPVCSRFSPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPK 407
Query: 247 LPGP---EHSPS-----ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 298
PGP E P + +P +P P+L P P + LS P
Sbjct: 408 EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP---PEESPLSPP-----------P 453
Query: 299 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--PLASHTV 356
E +P S E RLSP P L L + LS+P+ ES S P ++P P S
Sbjct: 454 EESPTSPPP-EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512
Query: 357 EIHEPNGMVPSEDLEPEVESSPELAPPP-ACPSESPVPIAPTAQPEELLNGAPSPPAVDL 415
E + + P E+ P L+PPP A P P +P + P E L +P P A L
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572
Query: 416 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATS----PAQEEEMEEEEEEEEGEAGEA 471
SP PEE + M+PP P +P + P S P +E + EE
Sbjct: 573 SP--PPEE------SPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 472 GEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLL 531
S PPE +P+ + + +S P ++ L V L
Sbjct: 623 ASRLSP-------PPEDSPM---------SPPPEESPMSPPPEVSRLSPL----PVVSRL 662
Query: 532 DAFKEANPAVPEVENQP----PAGSNPGPESEGSGVPPRPEEA 570
E +P P E P P S P E S P PE++
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Score = 69.7 bits (169), Expect = 2e-11
Identities = 100/392 (25%), Positives = 139/392 (35%), Gaps = 44/392 (11%)
Query: 205 TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS----PSESQPS 260
T P+ G L+ +A P V+ + + + + + P LP PE S P E P+
Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT 458
Query: 261 SPSPTP---SPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVE-------ESTPISRETGE 309
SP P SP P P S P LS P + E ES+P S
Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518
Query: 310 PYRLSPEPTPLAEPILEVEVT-------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPN 362
P LSP P LE ++ LS P ES S P + PT + P
Sbjct: 519 P--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576
Query: 363 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-- 420
P + P E SP PP A P +P + P E +P P A LSP E
Sbjct: 577 EESP---MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE--MEEEEEEEEGEAGEAGEAESEK 478
P E + PP + +P S SP EE EE EA
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP-- 691
Query: 479 GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 538
PPE +P + + +S+P + L ++ + + +
Sbjct: 692 ------PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLS 744
Query: 539 PAVPEVENQP-PAGSNPGPESEGSGVPPRPEE 569
P E P P + P++E + P+PEE
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
Score = 68.2 bits (165), Expect = 6e-11
Identities = 132/549 (24%), Positives = 194/549 (35%), Gaps = 98/549 (17%)
Query: 10 PPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSA 69
PPP SP P P P T+P P+A++++ P + P+ P + SR
Sbjct: 442 PPPEESPLSPPPEESP--TSP----PPEASRLSPPPEE----LPASPLPEALHLSRPLEE 491
Query: 70 APARPGP----------AAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQ 119
+P P P ++ P + P + + P S P ++
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551
Query: 120 YPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIA------- 172
P+ P P P + P E A P ++ P P M+ PP+ +
Sbjct: 552 SPLSP-PPEELPTSPPPE----ASRLSPPP--EESPMSPPPEESPMSPPPEASRLFPPFE 604
Query: 173 ------PKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226
P E + ++ + MS S +PP L P P V
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP-----LPVV 659
Query: 227 AVIVRPDDRSQGAIIADRPGLPGPEHSPSESQP--SSPSPTPSPSPVLEPGSE------P 278
+ + P + S P P PE SP+ P S SP P SP P + P
Sbjct: 660 SRLSPPPEES--------PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711
Query: 279 NLAVLSIPGDTMTTIQMSVE-------ESTPISRETGEPYRLSPEPTPLAEPILEVEVTL 331
+++S+P + + + E E +S EP+ LSP P EP L +
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH-LSPRP---EEPHLSPQAEE 767
Query: 332 SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED---LEPEVESSPELAPPPACPS 388
P+ E P P H E + P + L P+ E P L+P P P
Sbjct: 768 PHLSPQPE---EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE-EPHLSPVPEEPC 823
Query: 389 ESPVPIAPTAQPE-ELLNGAPSPPAVDLSPVSE-------PEEQAKEVTASMAPPTIPSA 440
SP P P+ E +P P LSP E PE+ +E AP +P
Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883
Query: 441 TPATAPSATSPAQEEEMEEEEE------EEEGEAGEAGEAESEKGGEELLPPESTPIPAN 494
P PS + E + E E EE +GE +L+PP+ P+P
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL---SPQLMPPD--PLPPP 938
Query: 495 LSQNLEAAA 503
LS + AAA
Sbjct: 939 LSPIITAAA 947
Score = 57.8 bits (138), Expect = 8e-08
Identities = 128/512 (25%), Positives = 170/512 (33%), Gaps = 124/512 (24%)
Query: 121 PVQPGAPGFYP-GASPTEF----GTYAGAYYPAQGVQQFPTGVAPAP-----VLMNQPPQ 170
P QPGA G P A+PT F T AG A G + P G P P + + PPQ
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 171 IAPKRERKTIRIRDP-NQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVI 229
+ + + +DP E A P P TG +P P +
Sbjct: 2167 VPAQ-----VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP------PMLGAS 2215
Query: 230 VRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS-PVLEPGSEPNLAVLSIPGD 288
RP G PG P QPS+P P P P L+ NLAV PG
Sbjct: 2216 SRPGAGQPGEFHTTPPGTP-------RHQPSTPDPFLKPRCPSLD-----NLAVPESPGV 2263
Query: 289 TMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV---EVTLSKP---VPESEFSS 342
+ EP LSP P + LEV E+ S P P F
Sbjct: 2264 G--------------GGKASEPL-LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVD 2308
Query: 343 SP----------LQAP-------TPLASHTVEIHEPN-GMVPSED-----LEPEVESSPE 379
SP L+ P TP AS VE P G+ P E L P S P+
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQ-VEPQSPGLGLRPQEPPPAQALAPSPPSHPD 2367
Query: 380 L----------APPPACPSESPVP------IAPTAQPEELLNGAPSPP---AVDLSPVSE 420
+ A PP P P P + P + P + + P+ P + SP++
Sbjct: 2368 IFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP 2427
Query: 421 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQE------EEMEEEEEEEEGEAGEAGEA 474
A+ S P S P + P + +++ + + E +AG
Sbjct: 2428 RPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHT 2487
Query: 475 ESEKGGEELLPPES------TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG 528
GG P +P+ N + T V P R +AVG
Sbjct: 2488 SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR----FTFPQAVG 2543
Query: 529 DLLDAFKEANPAVPEVENQPPAGSN----PGP 556
+ P VP+ PP G N PGP
Sbjct: 2544 E-----PSLKPPVPQPGLPPPHGINSHFGPGP 2570
Score = 52.8 bits (125), Expect = 3e-06
Identities = 121/550 (22%), Positives = 184/550 (33%), Gaps = 105/550 (19%)
Query: 4 APQSTGPPPAP-------SPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQ-----PR--- 48
+PQ+ GP +P SP +P P P + P+ + ++ S+ PR
Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848
Query: 49 QHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIP--SQISYPASQGAYYIP 106
H P +PP S P PG PA ++ + P + S G +
Sbjct: 849 SHLSPELEKPPLSPRPE---KPPEEPGQC----PAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 107 GQGRSTYVVPTQQYPVQP-GAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLM 165
G ++ P+ P G P P P + P ++P +
Sbjct: 902 EPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD---------------PLPPPLSPI-ITA 945
Query: 166 NQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQ 225
PP ++P E + P D E A TP P P+AN P+
Sbjct: 946 AAPPALSPLGE-----LEYPFGAKGDSDPESPLAAPILETPISPP------PEANCTDPE 994
Query: 226 VA--VIVRPDDRS-----QGAIIADRPGLPGP--EHS--PSESQPSSPSPTPSPSPVLEP 274
+I+ P S ++ P P +HS P S PS SP P V P
Sbjct: 995 PVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054
Query: 275 GSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKP 334
S P V+ + D +M E+ + EP SP P+P+ + + P
Sbjct: 1055 LS-PIGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGD----LSCPAPSP 1108
Query: 335 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI 394
P + S + PL +P L E++ SP L P +P+ +
Sbjct: 1109 APALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEV 1168
Query: 395 APTA------------QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASM----APPTIP 438
P Q E AP+PP + S + + AS + P +
Sbjct: 1169 YPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLG 1228
Query: 439 SATPATAPSAT---------SPAQEE-----------EMEEEEEEEEGEAGEAGEAESEK 478
S P S + SPA++E E ++ + G A G+AE EK
Sbjct: 1229 SPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEK 1288
Query: 479 GGEELLPPES 488
G P S
Sbjct: 1289 GRRRSSPARS 1298
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/336 (21%), Positives = 115/336 (34%), Gaps = 49/336 (14%)
Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPV-----LMNQPPQIAPKRERKTIRIRDPN 186
G +P T G P+ V P P L QPP P ++++ + +
Sbjct: 4052 GTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTA 4111
Query: 187 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 246
GG ++ SG+ + ++ P P V++ +P +Q + +P
Sbjct: 4112 GGGSH--GQLGSGSSSEASSVPHLLA----------QPSVSLGDQPGSMTQNLLGPQQPM 4159
Query: 247 LPGPEHSPSESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISR 305
L P + + QP P P PVL+ G P + ++ G +Q + ++ +
Sbjct: 4160 LERPMQNNTGPQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR- 4212
Query: 306 ETGEPYRLSPEPTPLAEPIL-------EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
LSP+ + +L V + P E +SPLQ
Sbjct: 4213 ------HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266
Query: 359 HEP-NGMVPSEDLEPEVESSPELAPPPACPSESPV--PIAPTAQPEELLNGAPSPPAVDL 415
P G + P + P L PP S PV P+ PT PS P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP--------PPSSPQEPK 4318
Query: 416 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 451
P P ++ T + PPT P P+ P
Sbjct: 4319 RPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
Score = 40.8 bits (94), Expect = 0.011
Identities = 90/382 (23%), Positives = 127/382 (33%), Gaps = 77/382 (20%)
Query: 147 PAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTP 206
P Q+ GV P+ L P A R+ + +RD T E+ S A+ P
Sbjct: 4631 PPSVQQKMVNGVTPSEELGEHPKDAASARDSERA-LRD--------TSEVKSLDLLAALP 4681
Query: 207 TPPQTGGG---LEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 263
TPP +E + ++P V P + + + P P E + + S
Sbjct: 4682 TPPHNQTEDVRMESDEDSDSPDSIV---PASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738
Query: 264 PT----PSPSPVLEPGSEPNLAV-LSIPGDTMTTIQ---MSVEESTPISRETGEPYRLSP 315
P P S + P ++P A+ L +PG T E S ++ L+
Sbjct: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNG 4798
Query: 316 EPTPLAEPILEVEVTLSKPVPESE---FSSSPLQAPTPLASHTVE--------------I 358
+AE LS +P S F SP +A T E
Sbjct: 4799 VMVAVAE-------LLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPD 4851
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ------------------P 400
P+ + + + P +L ESP P PT P
Sbjct: 4852 TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPP 4911
Query: 401 EELLNGAPSPPAVDL--SPVSEPEEQAKEV-TASMAPPTIPSATPATAPSATSPAQEEEM 457
EE PSPP L SP S P E E+ T +A P +PS P A+SP
Sbjct: 4912 EE-----PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP----LASSPESARPK 4962
Query: 458 EEEEEEEEGEAGEAGEAESEKG 479
EEGE + KG
Sbjct: 4963 PRARPPEEGEDSRPPRLKKWKG 4984
Score = 39.7 bits (91), Expect = 0.024
Identities = 161/747 (21%), Positives = 244/747 (32%), Gaps = 189/747 (25%)
Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPR----QHFYPS------ 54
P+ PPP LP + P + V S + +P PR + F PS
Sbjct: 2385 PRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444
Query: 55 -----RAQPPSSAASRVQSA---APARPGPAAHVYPAGSQV----------MMIPS---- 92
++PPS SR A P RP P + AGS +P+
Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504
Query: 93 --QISYPASQGAYYIPGQGRSTYV---------------VPTQQYPV-QPGAP------- 127
P+ Q ++ G +V P+ + PV QPG P
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS 2564
Query: 128 ---------------------GFYPGASPTEFGTYAGAYYPAQGVQQF-PTGVAPAPVLM 165
F+P SP G +G+ + G+ P V P P
Sbjct: 2565 HFGPGPTLGKPQSTNYTVATGNFHPSGSP--LGPSSGSTGESYGLSPLRPPSVLPPPAPD 2622
Query: 166 NQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGG------LEPQA 219
P ++ +++ I P + +D + S TA P G LE Q
Sbjct: 2623 GSLPYLSHGASQRS-GITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 220 NGETPQVAV----IVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS------------ 263
+ + + I R R + A G GP S ++PSSP+
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWG-AEPSSPAFEQLSRGQTPFA 2740
Query: 264 ------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 311
P+ P+L PGS P+ LS P T M V S + + Y
Sbjct: 2741 GTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDV-NSRQLVGGSQAFY 2799
Query: 312 RLSPEPTPL--------------AEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTV 356
+ +P P L A + +S P + QA +PLA +
Sbjct: 2800 QRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIST 2859
Query: 357 EIHEPNGMV-----PSEDLEPEVESSPELAP---------PPACP-----SESPVPIAPT 397
+ P V P++ +E L P PP P SE P +AP
Sbjct: 2860 RLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPE 2919
Query: 398 AQPEELLNGAP-----SPPAVDLSPVSEPEEQAKEVTASMAPPTI---PSAT------PA 443
++G P +PPA +L+ P K T + PS+T P
Sbjct: 2920 GLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPL 2979
Query: 444 TAPSATSPAQEEEMEEE-------EEEEE----GEAGEAGEAESEKGGEELLPPESTPIP 492
+ P ++ E++++ E++EE G + + + E G E L +
Sbjct: 2980 ALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLD 3039
Query: 493 ANLS-QNLEAAAATQVAVSVPKRR-------RKIKELNKKEAVGDLLDAFKEANPAVPEV 544
L+ + A T + ++ R ++ N+K LL E P PE
Sbjct: 3040 DLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGV-EPGPLGPE- 3097
Query: 545 ENQPPA--GSNPGPESEGSGVPPRPEE 569
E PPA S P S V P+ EE
Sbjct: 3098 ERPPPAADASEPRLASVLPEVKPKVEE 3124
Score = 38.1 bits (87), Expect = 0.069
Identities = 91/396 (22%), Positives = 128/396 (32%), Gaps = 48/396 (12%)
Query: 198 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD-DRSQGAIIADRPGLPGPEHSPSE 256
SG T STPT P T G + +G + + R + D G + P L + P+
Sbjct: 1976 SGGTTPSTPTTPTTEG----EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031
Query: 257 SQ--PSSPS------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST- 301
Q P S P +P L+ + A Q++ +
Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG 2091
Query: 302 PISRETGEP---YRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
I+R+T P R+ P+P L P T+ F SP S +
Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTI--------FIGSPTTPAGLSTSADGFL 2143
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418
P G VP D E+ P PS+ P +AP E AP SP
Sbjct: 2144 KPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT 2203
Query: 419 SEPEEQAKEVTASMAP--------PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 470
P Q + AS P T P TP PS P + + E+
Sbjct: 2204 GAP-AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 471 AGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDL 530
G K E LL +P P S+ ++ S P + G
Sbjct: 2263 VG---GGKASEPLL----SPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTH 2315
Query: 531 LDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPR 566
L + P V + P A S P+S G G+ P+
Sbjct: 2316 LGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQ 2350
Score = 38.1 bits (87), Expect = 0.069
Identities = 92/473 (19%), Positives = 158/473 (33%), Gaps = 58/473 (12%)
Query: 9 GPPPAPSPGLPQP--AFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRV 66
GP P P LP P A G V TP + P +P Q PS PSS
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQ--LPS----PSSQLPTE 4333
Query: 67 QSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQ-PG 125
P PG P G + P ++S A+Q A + +G + P Q P
Sbjct: 4334 AQLPPTHPGTPK---PQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390
Query: 126 APGFYPGASPTEFGTY---AGAYYPAQGVQQFPTGVAPAPVL--MNQPPQIAPKRERKTI 180
PG G A Q ++ P + V N P AP +
Sbjct: 4391 QSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL 4450
Query: 181 RIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAI 240
++ G + ++++ A+ T + GL + NG D +
Sbjct: 4451 LAGPRSEAGHLLLQKLLR-AKNVQLST-GRGSEGLRAEINGHI----------DSKLAGL 4498
Query: 241 IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES 300
G P + + +P +P P + D + + + + +
Sbjct: 4499 EQKLQGTPSNKEDAAARKPLTPKPKR----------------VQKASDRLVSSRKKLRKE 4542
Query: 301 TPISRETGEPYRLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 358
+ +L E + PL EP + +L P S P+ + L
Sbjct: 4543 DGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFG----SGCPVNGQSQLRGAFGSG 4598
Query: 359 HEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPV 418
P G D ++ + L+ PP PS P P P + ++++NG P+ +L
Sbjct: 4599 ALPTG----PDYYSQLLTKNNLSNPPTPPSSLP-PTPPPSVQQKMVNGV--TPSEELGEH 4651
Query: 419 SEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEA 471
+ A++ ++ + + A T P + E E +E+ ++ ++
Sbjct: 4652 PKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDS 4704
Score = 35.8 bits (81), Expect = 0.34
Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 57/215 (26%)
Query: 246 GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 305
G PGP+ P + + P P P PG+ VL
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--------------------- 4303
Query: 306 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 365
P +P P+ EP P Q P+P + E P
Sbjct: 4304 ----PVHPTPPPSSPQEP------------------KRPSQLPSPSSQLPTEAQLP---- 4337
Query: 366 PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 425
P+ P+ + P L PPP S + +A T + L P P +L+ +PE+
Sbjct: 4338 PTHPGTPKPQ-GPTLEPPPGRVSPAAAQLADTLFSKGL---GPWDPPDNLAETQKPEQ-- 4391
Query: 426 KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEE 460
+S+ P + P A+ + ++E EE
Sbjct: 4392 ----SSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422
Score = 32.0 bits (71), Expect = 4.9
Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 19/76 (25%)
Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPP-SSA 62
AP P P PSP P PA PP T P+V P++P A+PP S
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPP--TEPLV---------ELPTEP-------LAEPPVPSP 4949
Query: 63 ASRVQSAAPARPGPAA 78
S ARP P A
Sbjct: 4950 LPLASSPESARPKPRA 4965
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 82.0 bits (201), Expect = 4e-15
Identities = 129/513 (25%), Positives = 168/513 (32%), Gaps = 78/513 (15%)
Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAAS 64
P PP APSP P PPG P V S P A M PS PS A
Sbjct: 648 PAPVPPPEAPSPFRAPPFHPPGPM-PSVGSMPSAGPM-----------PSAGPMPS--AG 693
Query: 65 RVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQP 124
V SA P P A H+ + +P +S P + P
Sbjct: 694 PVPSARPGPPTTANHLG------LSVPGLVSVPPR----------------------LLP 725
Query: 125 GAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRD 184
G G++ +G P + G P P ++ + A E I +
Sbjct: 726 GPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVE---ISLES 782
Query: 185 PNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADR 244
+ I E + P PP +G P A P + V + + +
Sbjct: 783 DSDDSVVIVPEGLP-----PLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPE-----EL 832
Query: 245 PGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV---EEST 301
P PGP P P P P P P L P P + +T I ++ EE
Sbjct: 833 PAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEE 892
Query: 302 PISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI--H 359
E E E E E E + E EF + L E
Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952
Query: 360 EPNGMVPSEDLE-----PEVESSPELAPPPACPSESPVPIAPT-AQPEELLNGAPSPPAV 413
E + EDLE EVE PPP P P P +P QPE P P
Sbjct: 953 EEEELEEVEDLEFGTAGGEVEEGAP--PPPTLPPALPPPESPPKVQPE------PEPEPG 1004
Query: 414 DLSPVSEP---EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 470
L V EP EE+ + ++AP +PS SPA +E EEE
Sbjct: 1005 LLLEVEEPGTEEERGADTAPTLAPEALPSQGEVER-EGESPAAGPPPQELVEEEPSAPPT 1063
Query: 471 AGEAESEKGGEELLPPESTPIPANLSQNLEAAA 503
E E+E G +++ PP TP + EA A
Sbjct: 1064 LLEEETEDGSDKVQPPPETPAEEEMETETEAEA 1096
Score = 68.9 bits (167), Expect = 4e-11
Identities = 92/360 (25%), Positives = 129/360 (35%), Gaps = 29/360 (8%)
Query: 250 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 309
P P S PS P PS P + N LS+PG ++ + +
Sbjct: 678 PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737
Query: 310 PYRLSPEPTPLAEPILEVEVTLSKPVPESEF------SSSPLQAPTPLASHTVEIHEPNG 363
P L+P TP P + + T VP F +S ++ S + P G
Sbjct: 738 PI-LAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794
Query: 364 MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL------LNGAPSPPAVDLSP 417
+ P P + P +AP P+ SP P+ +PEEL L P PP P
Sbjct: 795 LPPLPPPPPSGATPPPIAPTGP-PTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852
Query: 418 VSEPEEQA--KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 475
V+ P Q + PP + +++ +EEE EEEEEEEE E E E
Sbjct: 853 VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912
Query: 476 SEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFK 535
E+ EE E + E + + +EL + E + + A
Sbjct: 913 EEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL-EFGTAGG 970
Query: 536 EANPAVPEVENQPPAGSNPGPESEGSGVP-PRPE-----EADETWDSKEDKIHNAENIQP 589
E P PPA P PES P P PE E +E +E A + P
Sbjct: 971 EVEEGAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028
Score = 45.8 bits (107), Expect = 3e-04
Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 41/321 (12%)
Query: 319 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 378
P P+ + T P P P +AP+P + H P M P V S P
Sbjct: 633 PRVPPLQPMGPTCPTPAPVP-----PPEAPSPFRAPP--FHPPGPM-------PSVGSMP 678
Query: 379 ELAPPPAC---PSESPVPIAPTAQPEELLN-GAPSPPAVDLSPVSEPEEQAKEVTASMAP 434
P P+ PS PVP A P + G P V + P P + ++ P
Sbjct: 679 SAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738
Query: 435 PTIPSATPATA--PSATSPAQ--EEEMEEEEEEEEGEAGEAGEAESEKGG---EELLPPE 487
PS TP P T + ++EE + + E++S+ E LPP
Sbjct: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798
Query: 488 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 547
P P+ + A A + + +EL A L P VP
Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL---PAAPGPLPPPPPPPPPVPGPVTL 855
Query: 548 PPAGSNPGPESEGSGVPPRPEE---------ADETWDSKEDKIHNAENIQPGEQKYEYK- 597
PP P + G G PP EE +DE + +E++ E + E+ +E +
Sbjct: 856 PPPQLVP-EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914
Query: 598 --SDQWKPLNLEEKKRYDREF 616
+++ EE++ ++ EF
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEF 935
Score = 31.6 bits (70), Expect = 6.4
Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 3/42 (7%)
Query: 848 QKEFEKDKDDDEVF---EKKQKEMDEAATAEERGRLKEELEE 886
+++FE++++D+E + E++++E E EE G L+EE EE
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 82.0 bits (201), Expect = 4e-15
Identities = 130/537 (24%), Positives = 190/537 (35%), Gaps = 85/537 (15%)
Query: 10 PPPAPSPGLPQPA-FPPGQTAPVVFSTPQATQMN---------TPSQPRQHFYPSRAQPP 59
P PAP+PG A P T + F+ P T N TP P PS P
Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
Query: 60 SSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRST---YVVP 116
+ + S VQ+ P G ++P ++ P + + + G G V P
Sbjct: 900 AQSVSPVQAPPP------------GGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSP 947
Query: 117 TQQYPVQPGA--PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPK 174
PVQ GA P +P T +G P P P +QP ++
Sbjct: 948 PFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLS------PATLPGPT--SQPQKVLLP 999
Query: 175 RERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD- 233
+ ++ + GG + + A T T + P V+P
Sbjct: 1000 SSTRITYVQ--SAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLL 1057
Query: 234 DRSQGAIIADRPG------LPGPEHSPSESQPSSP--------SPTPSPS-PVLEPGSEP 278
Q ++A PG +P P+ P+ + P P SP P+ S P+ +P P
Sbjct: 1058 SAGQAPLLA--PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP 1115
Query: 279 NLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPES 338
V ++ T T ++ P + T P SP P+ A +T S P++
Sbjct: 1116 PSLVYTVATST-TPPAATILPKGPPAPATATPAPTSPFPSATAG-----SMTYSLVAPKA 1169
Query: 339 EFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA 398
Q P+P A V+ + +P E P P P P E P P+
Sbjct: 1170 -------QRPSPKAPQKVKAAIAS--IPVGSFEAGASGRP--GPAPRQPLE-PGPVREPT 1217
Query: 399 QPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME 458
PE L G P+PPA P PE TA +PP P A T SA P E M
Sbjct: 1218 APESELEGQPTPPA----PPPLPETWTP--TARSSPPLPPPAEERT--SAKGP---ETMA 1266
Query: 459 EEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRR 515
+ + G+ E GE PP P PA +++ + A P+R+
Sbjct: 1267 SKFPSSSSDWRVPGQG-LENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERK 1322
Score = 65.9 bits (159), Expect = 3e-10
Identities = 113/428 (26%), Positives = 156/428 (36%), Gaps = 57/428 (13%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
K P+S G P P + A PP ++ T + P++ Q A+ PS+
Sbjct: 601 KRPESVGGLEPPGPSVI--AAPPSGGGNIL-----QTLVLPPNKEEQE--GGGARVPSAP 651
Query: 63 ASRVQSAAPARP--GPAAH-----VYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVV 115
A + APA P PAA V P S + I S+ +P S A P
Sbjct: 652 APSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASK-PFPTSGRAEASPND------- 703
Query: 116 PTQQYPVQPGAPGFYPGASPTEFGTY------AGAYYPAQGVQQFP----TGVAPAPV-- 163
T + G PG SP A A PA + P G APA V
Sbjct: 704 -TAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTN 762
Query: 164 -LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGE 222
L+ P AP + GG SGA S P P G L+P A G+
Sbjct: 763 LLVGTPGYGAPAPPAVQFIAQGAPGGGTTAG----SGAGAGSGPNGPVPLGILQPGALGK 818
Query: 223 TPQVAVI--VRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL 280
+ + + P Q + P P + PS P+PT S L PG+ N
Sbjct: 819 AGGITQVQYILPTLPQQLQVAP----APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNG 874
Query: 281 AVLSIPGDTM-TTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESE 339
VL+ T I SV + P ++ P + +P P A+ +L +V + P
Sbjct: 875 KVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQ-APPPGGSAQ-LLPGKVLVPLAAPSMS 932
Query: 340 FSSSPLQAPTPLASHTVEIHEPNGMVPSE---DLEPEVESSPELAPPPACPSESPVPIAP 396
P PL S + NG P L P S+P PP P+ P P
Sbjct: 933 VRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLP---GP 989
Query: 397 TAQPEELL 404
T+QP+++L
Sbjct: 990 TSQPQKVL 997
Score = 52.8 bits (125), Expect = 3e-06
Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 45/292 (15%)
Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAA 63
AP G P PSP LP PG PV+ + + T S P AQP +
Sbjct: 1066 APGQVGVSPVPSPQLPPACAAPG--GPVITAFYSGSPAPTSSAP-------LAQPSQAPP 1116
Query: 64 SRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTY--VVPTQQYP 121
S V + A + PAA + P G + PA + G TY V P Q P
Sbjct: 1117 SLVYTVATSTTPPAATILPKGPPA----PATATPAPTSPFPSATAGSMTYSLVAPKAQRP 1172
Query: 122 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTG-VAPAPVLMNQPPQIAPKRERKTI 180
P AP A A P + +G PAP QP + P RE
Sbjct: 1173 -SPKAPQKVKAAI---------ASIPVGSFEAGASGRPGPAP---RQPLEPGPVREPTAP 1219
Query: 181 RIR---DPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQ 237
P E + +S P PP E + + + P+ P S
Sbjct: 1220 ESELEGQPTPPAPPPLPETWTPTARSSPPLPPPA----EERTSAKGPETMASKFPSSSSD 1275
Query: 238 GAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDT 289
+ PG + + +P +P P+P+P+P + PG + GDT
Sbjct: 1276 WRV----PG----QGLENRGEPPTP-PSPAPAPAVAPGGSSESSSGRAAGDT 1318
Score = 32.7 bits (73), Expect = 2.9
Identities = 42/178 (23%), Positives = 59/178 (33%), Gaps = 33/178 (18%)
Query: 310 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369
P+ +P P +P E + S PV + Q+ P S V P G S D
Sbjct: 42 PFLAPSQPDPSVQPS-EAQQPASHPVASN-------QSKEPAESAAVAHERPPGGTGSAD 93
Query: 370 LEPEVESSPELAPPPACPSESPVP------------IAPTAQPEELLNGAPSPPAVDLSP 417
E PP A ESP P P EE +G P P +D
Sbjct: 94 PE---------RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLD--- 141
Query: 418 VSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 475
SE E + S+ P I P S + + + E++G + E +
Sbjct: 142 -SETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKD 198
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 81.3 bits (199), Expect = 7e-15
Identities = 132/568 (23%), Positives = 202/568 (35%), Gaps = 102/568 (17%)
Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71
P+ GL +PA ++ S+P + + PR +PS+ +P A R P
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278
Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131
R A + P S + PS + P+ P S +P+ P P +
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPS-------PSAPPSLQTLPSP--PATPPSQATTS 329
Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD 191
SPT T+ ++ P+ + T AP + PP AP
Sbjct: 330 LGSPTLQATH--SFLPSPPLSPLATPPPQAPPALALPPLQAP------------------ 369
Query: 192 ITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLP-GP 250
P+PP +P ++ + P ++ A+ P P
Sbjct: 370 --------------PSPP------------ASPPLSPLATPSPQAPNALAVHLLQAPFSP 403
Query: 251 EHSPSESQPSSPSPTPSPSPVLEPGSE--PNLAV--LSIPGDTMTTIQMSVEESTPISRE 306
SP P SP +P SP P S+ P+LA L +P + MS + P
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP---- 459
Query: 307 TGEPYRLSPEPTPLAEPILEVEVTLSKPVPES--EFSSSPLQA-PTPLASHTVEI-HEPN 362
P PLA P L+ L+KP P++ ++ PLQA P+P AS + P+
Sbjct: 460 -------PQAPPPLAAPPLQ----LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 363 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPE 422
+P L + P APP VP +P A P P P D S VS P
Sbjct: 509 ASLPMSPL----ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS-VSGP- 562
Query: 423 EQAKEVTASMA--PPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 480
+T ++A PP PS +P++ S A EE G +GG
Sbjct: 563 ----RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGG 613
Query: 481 EELLPPESTPI----PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF-- 534
PP + PA S+ A + A P + + + +
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673
Query: 535 KEANPAVPEVENQPPAGSNPGPESEGSG 562
+ A PA ++ P G++ G + G+G
Sbjct: 674 ESATPAPGALDPGPSPGTSGGKAAAGAG 701
Score = 53.1 bits (126), Expect = 2e-06
Identities = 125/532 (23%), Positives = 169/532 (31%), Gaps = 97/532 (18%)
Query: 4 APQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQ----------------- 46
A + GP + P P+ PP +AP T + PSQ
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342
Query: 47 PRQHFYPSRAQPPSSAASRVQSAAPARPGPAAH--VYPAGSQVMMIPSQISYPASQGAYY 104
P P PP + + A P P A + P + P+ ++ Q +
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Query: 105 IPGQGRSTYVVPTQQYPVQPGA-PGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPV 163
P P Q P P A P P A+P + A P Q V P P
Sbjct: 403 PPPS-------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSP 454
Query: 164 LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGET 223
PPQ P +++ P PPQ L T
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKP----------------------PPQAPPAL------AT 486
Query: 224 PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVL 283
P + + P A PG SPS S P SP TP P VL
Sbjct: 487 PPLQALPSPP--------ASFPG--QAPFSPSASLPMSPLATPPPQAP---------PVL 527
Query: 284 SIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTP---LAEPILEVEVTLSKPVPESEF 340
+ P + V S P S P R P P P ++ P L + + P P S
Sbjct: 528 AAP-------LLQVPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579
Query: 341 SSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQP 400
SS L P LA H+ + D P E +PPP + P A + P
Sbjct: 580 PSSTLSGP-DLAGHSSSATSTPEELRGYDSGP--EGGAAASPPPDAELAACHPAAWSRGP 636
Query: 401 EELL--NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEME 458
L GAP P + P + P A + SATP AP A P
Sbjct: 637 APPLAFRGAPGAP-LPWPPATGP-GSADGLCTIYETEGPESATP--APGALDPGPSPGTS 692
Query: 459 EEEEEEEGEAGEAGEA--ESEKGGEELLPPESTPIPANLSQNLEAAAATQVA 508
+ AG + + ++ G L +++ + LS+ L AAA A
Sbjct: 693 GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 744
>gi|33386693 poly(A) binding protein interacting protein 1 isoform 2
[Homo sapiens]
Length = 400
Score = 80.9 bits (198), Expect = 9e-15
Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)
Query: 701 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 760
P+++ + +P+ ++A VLM++ + +N E S + G ED L
Sbjct: 26 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 79
Query: 761 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 815
V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS
Sbjct: 80 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 139
Query: 816 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875
A +C L + + NFR+LLL RC+ E+E
Sbjct: 140 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 172
Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 923
+K++ + ++ R+R + F+GEL+ L++ + + + + + L
Sbjct: 173 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 228
Query: 924 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 980
N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML
Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288
Query: 981 DVLDLRGSNW 990
+++LR SNW
Sbjct: 289 KLVELRSSNW 298
>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
[Homo sapiens]
Length = 479
Score = 80.9 bits (198), Expect = 9e-15
Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)
Query: 701 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 760
P+++ + +P+ ++A VLM++ + +N E S + G ED L
Sbjct: 105 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 158
Query: 761 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 815
V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS
Sbjct: 159 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 218
Query: 816 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 875
A +C L + + NFR+LLL RC+ E+E
Sbjct: 219 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 251
Query: 876 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 923
+K++ + ++ R+R + F+GEL+ L++ + + + + + L
Sbjct: 252 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 307
Query: 924 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 980
N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML
Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367
Query: 981 DVLDLRGSNW 990
+++LR SNW
Sbjct: 368 KLVELRSSNW 377
Score = 31.6 bits (70), Expect = 6.4
Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 20/123 (16%)
Query: 361 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 403
PNG P+E L+P P PPP E P P P A PE+
Sbjct: 32 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQT 91
Query: 404 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT---PATAPSATSPAQEEEMEEE 460
P + D P E + +AP + + P PS S + E E+
Sbjct: 92 RPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDG 151
Query: 461 EEE 463
E+
Sbjct: 152 CED 154
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 79.3 bits (194), Expect = 3e-14
Identities = 149/666 (22%), Positives = 225/666 (33%), Gaps = 149/666 (22%)
Query: 41 MNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQ 100
+ P +P + P +PP++ S AAP P PA P S
Sbjct: 519 LGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG--------------LSP 564
Query: 101 GAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAP 160
G P + + P+ Y Q G P P G+A
Sbjct: 565 GGSRRPPRSPERTLSPSSGYSSQSGTPTLP------------------------PKGLAG 600
Query: 161 APVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQAN 220
P P + P + + +R P G ++ + S ++S P P G PQ
Sbjct: 601 PPA---SPGKAQPPKPERVTSLRSP---GASVSSSLTSLCSSSSDPAPSDRSG---PQ-- 649
Query: 221 GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT----PSPSPVLEPGS 276
++ DR +I P +P P SP S+P SP+P +P+ V P S
Sbjct: 650 -------ILTPLGDR---FVIPPHPKVPAP-FSPPPSKPRSPNPAAPALAAPAVVPGPVS 698
Query: 277 EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 336
+ + S P T T ++ES IS++ P P P P P P P
Sbjct: 699 TTDASPQSPP--TPQTTLTPLQESPVISKDQSPP----PSPPPSYHP----------PPP 742
Query: 337 ESEFSSSPLQAPTPLASHTVE--IHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI 394
++ ++AP+ AS T E + +PN PPP P E + +
Sbjct: 743 PTKKPEVVVEAPS--ASETAEEPLQDPNWP----------------PPPPPAPEEQDLSM 784
Query: 395 APTAQPEELLNGAPSP----PAVDLSPVSEPEEQAKEVTASM----APPTIPSATPATAP 446
A PEE SP P+ VS P + TA P P A PA AP
Sbjct: 785 ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844
Query: 447 SATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQ 506
++++P ++ ++E + G E G L+ P + S A T
Sbjct: 845 ASSAPGHVAKLPQKEPV---GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901
Query: 507 V----AVSVPKRRRKIKELNKKEAVGDLLDAFKEANP-AVPEVENQPPAGSNPGPESEGS 561
A P RR + A L A ++ E A N PE+E
Sbjct: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE-- 959
Query: 562 GVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQ 621
PRP ++ + S G +K + + +P++ E + R + +
Sbjct: 960 ---PRPPQSPASTAS--------FIFSKGSRKLQLE----RPVSPETQADLQRNLVAELR 1004
Query: 622 FIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTR 681
I S Q+P P K+P P R + P +PS+ T
Sbjct: 1005 SI--SEQRPPQAP----------KKSPKAPPPVARKPSVGVPPPASPSYPRAEPLT---- 1048
Query: 682 GPPRGG 687
PP G
Sbjct: 1049 APPTNG 1054
Score = 53.5 bits (127), Expect = 2e-06
Identities = 115/484 (23%), Positives = 162/484 (33%), Gaps = 98/484 (20%)
Query: 3 KAPQSTGPPPA----PSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQP 58
K P PPP+ P+P P A P PV ST A+ + P+ P+ P + P
Sbjct: 665 KVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV--STTDASPQSPPT-PQTTLTPLQESP 721
Query: 59 PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118
S+ QS P+ P P+ H P P + + S
Sbjct: 722 ---VISKDQSPPPS-PPPSYHPPPP-------------PTKKPEVVVEAPSASETAEEPL 764
Query: 119 QYPVQPGAPGFYP---GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKR 175
Q P P P P S +F A++ + P G + +P L++ P A
Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE--PAGPSGSPELVSSP--AASSS 820
Query: 176 ERKTIRIRDPNQGGKDITEEIMSGARTA---------STPTPPQTGGGLEPQANGE---T 223
++I+ P + A +A P GGG + G T
Sbjct: 821 SATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880
Query: 224 PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ-PSSPSPTPSPSPVLEPGSEPNLAV 282
P + +VR RS GA G P P PS Q P + + SPV P S + AV
Sbjct: 881 PSLLQMVRL--RSVGA----PGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAV 934
Query: 283 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 342
+ ++ E ++ G P EP P P SK S
Sbjct: 935 ------RLKACSLAASEGLSSAQPNGPP---EAEPRPPQSPASTASFIFSK-------GS 978
Query: 343 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEE 402
LQ P++ T + N L E+ S E PP A P +SP P A+
Sbjct: 979 RKLQLERPVSPETQADLQRN-------LVAELRSISEQRPPQA-PKKSPKAPPPVARKPS 1030
Query: 403 LLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 462
+ G P P A P+ P A P TAP ++ + E
Sbjct: 1031 V--GVPPP----------------------ASPSYPRAEPLTAPPTNGLPHTQDRTKREL 1066
Query: 463 EEEG 466
E G
Sbjct: 1067 AENG 1070
Score = 39.3 bits (90), Expect = 0.031
Identities = 57/256 (22%), Positives = 87/256 (33%), Gaps = 29/256 (11%)
Query: 254 PSESQPSSPSPTPSPSP----VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 309
P PSS S T S S ++ GS LS G + + S ++ + G
Sbjct: 404 PRSRHPSSSSDTWSHSQSSDTIVSDGS-----TLSSKGGSEGQPESSTASNSVVPPPQGG 458
Query: 310 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 369
R SP AE + + S + S L+ P P T +H+ VP
Sbjct: 459 SGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGP 518
Query: 370 L----EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPS-PPAVDLSPVSEPE-- 422
L +PE + P+L PP AP P + P P P PE
Sbjct: 519 LGLPPKPERKQQPQLPRPPTTGGSEGAGAAP-CPPNPANSWVPGLSPGGSRRPPRSPERT 577
Query: 423 -EQAKEVTASMAPPTIPS---ATPATAPSATSPAQEEEMEEEEEEEEGE--------AGE 470
+ ++ PT+P A P +P P + E + +
Sbjct: 578 LSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS 637
Query: 471 AGEAESEKGGEELLPP 486
+ A S++ G ++L P
Sbjct: 638 SDPAPSDRSGPQILTP 653
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 79.0 bits (193), Expect = 4e-14
Identities = 115/506 (22%), Positives = 165/506 (32%), Gaps = 109/506 (21%)
Query: 12 PAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQSAAP 71
P P P P+P P + + +A + P + + P P + + SA P
Sbjct: 716 PPPRPTAPKPLLPRREES-------EAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATP 768
Query: 72 ARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYP 131
P+ P S P +S P G TY PTQ +QP APG P
Sbjct: 769 LHFPPS----PFPSSTGPGPHYLSGPLPPG----------TYSGPTQL--IQPRAPG--P 810
Query: 132 GASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKD 191
A P VAP P L P A E + P G
Sbjct: 811 HAMP----------------------VAPGPALYPAP---AYTPELGLVPRSSPQHG--- 842
Query: 192 ITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPE 251
++S P PP G P P++A+ VRP + +I A P P
Sbjct: 843 ----VVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPR 898
Query: 252 HSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 311
+P+ + P P P P P+ P + P A IP + + P
Sbjct: 899 PNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP--------- 949
Query: 312 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 371
R+ P+P P + P P F P Q P PL + + G++P +
Sbjct: 950 RIGPQPQPHPQ-----------PHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998
Query: 372 PEVESSPELAPPP--------ACPSESPVPI----------APTAQPEELLNGAPSPPAV 413
P L PP P++ P+P P P L P+P
Sbjct: 999 PYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTR 1058
Query: 414 DLSPVSEPEEQAKEVTASMAPPT---IPSATPATAPSATSPAQEEEMEEEEEEEEGEA-- 468
+ P + P +A + P+ +PS P+ P P + E G A
Sbjct: 1059 PMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPV-PPRPPAAEPPPCLRRGAAAA 1117
Query: 469 --------GEAGEAESEKGGEELLPP 486
+ G +S GG+ LL P
Sbjct: 1118 DLLSSSPESQHGGTQSPGGGQPLLQP 1143
Score = 60.5 bits (145), Expect = 1e-08
Identities = 78/286 (27%), Positives = 102/286 (35%), Gaps = 50/286 (17%)
Query: 5 PQSTGPPPAPSPGLPQPAF--PPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSA 62
P T P P P+P P P F PP Q P ++ P + P+Q HF S P
Sbjct: 892 PSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ--HHF--SSGIPAGFP 947
Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVM-MIPSQISYPASQGAYYIPGQGRSTYVVPTQQYP 121
A R+ P P H P SQ P Q P Q + P Q + P YP
Sbjct: 948 APRI------GPQPQPHPQPHPSQAFGPQPPQQPLPL-QHPHLFPPQAPG-LLPPQSPYP 999
Query: 122 V--QPGAPG---------FYPGASPTEFGTYAGAY-YPAQGVQQ---FPTGVAPAPVLMN 166
QPG G YPG + ++GA +P+ G Q P PAP
Sbjct: 1000 YAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRP 1059
Query: 167 QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQV 226
PQ AP + IR P+ G+ +P P G + P+ P
Sbjct: 1060 MGPQAAP------LTIRGPSSAGQS-----TPSPHLVPSPAPSPGPGPVPPRPPAAEP-- 1106
Query: 227 AVIVRPDDRSQGAIIAD-RPGLPGPEHSPSESQPSSPSPTPSPSPV 271
P +GA AD P +H ++S P P P+ V
Sbjct: 1107 -----PPCLRRGAAAADLLSSSPESQHGGTQS-PGGGQPLLQPTKV 1146
Score = 54.3 bits (129), Expect = 9e-07
Identities = 78/284 (27%), Positives = 102/284 (35%), Gaps = 47/284 (16%)
Query: 10 PPPAPSPGLPQPAFPPGQTAPVV---FSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRV 66
PP A P P P F + A V +T + Q PS P+ A PP
Sbjct: 855 PPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFP--- 911
Query: 67 QSAAPARPGPAAHVYPAGSQVMMIPSQISY----PASQGAYYI-PGQGRSTYVVPTQQYP 121
P +P P + YPAG++ IP+Q + PA A I P P+Q +
Sbjct: 912 --VPPPQPLPTPYTYPAGAK-QPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFG 968
Query: 122 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPP-----QIAPKRE 176
QP P P F A P Q P AP P ++ QPP Q+ P
Sbjct: 969 PQPPQQPL-PLQHPHLFPPQAPGLLPPQS----PYPYAPQPGVLGQPPPPLHTQLYPGPA 1023
Query: 177 RKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRS 236
+ + SGA +P PPQ P A G P RP
Sbjct: 1024 QDPLPAH--------------SGALPFPSPGPPQPPH--PPLAYGPAPS----TRPMGPQ 1063
Query: 237 QGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPV--LEPGSEP 278
+ P G + +PS SP+P+P P PV P +EP
Sbjct: 1064 AAPLTIRGPSSAG-QSTPSPHLVPSPAPSPGPGPVPPRPPAAEP 1106
Score = 33.5 bits (75), Expect = 1.7
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 3 KAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61
++P ++ P PA PGLP + P ++ P+ S+P P P+ P + PSS
Sbjct: 1514 ESPVASLPGPAEPPGLPPASLP--ESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSS 1570
Score = 32.3 bits (72), Expect = 3.8
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 15/127 (11%)
Query: 319 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 378
P +P+ ++ +P+ L P++S I + + + P LE V S P
Sbjct: 1464 PPCKPLASASISQKNHLPQDS-QDLVLGGDVPISSIQATIAKLS-IRPPGGLESPVASLP 1521
Query: 379 ELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 438
A PP P P + PE + SPP P+S P +A + P P
Sbjct: 1522 GPAEPPGLP--------PASLPESTPIPSSSPP-----PLSSPLPEAPQPKEEPPVPEAP 1568
Query: 439 SATPATA 445
S+ P ++
Sbjct: 1569 SSGPPSS 1575
>gi|169212085 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 516
Score = 77.8 bits (190), Expect = 8e-14
Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)
Query: 683 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 733
P R P G LP L P+++ + +P+ ++A VL ++ + +N E
Sbjct: 115 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 173
Query: 734 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 788
S + G ED V+ LN LT P F+ ++Q + +
Sbjct: 174 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 228
Query: 789 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 848
T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+
Sbjct: 229 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 284
Query: 849 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 907
E+E +K++ + ++ R+R + F+GEL+
Sbjct: 285 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 317
Query: 908 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 953
L++ + + + + + L N +++L C +LL G L+ EK K
Sbjct: 318 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 377
Query: 954 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990
M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 378 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 414
>gi|239752553 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 457
Score = 77.8 bits (190), Expect = 8e-14
Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)
Query: 683 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 733
P R P G LP L P+++ + +P+ ++A VL ++ + +N E
Sbjct: 56 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 114
Query: 734 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 788
S + G ED V+ LN LT P F+ ++Q + +
Sbjct: 115 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 169
Query: 789 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 848
T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+
Sbjct: 170 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 225
Query: 849 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 907
E+E +K++ + ++ R+R + F+GEL+
Sbjct: 226 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 258
Query: 908 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 953
L++ + + + + + L N +++L C +LL G L+ EK K
Sbjct: 259 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 318
Query: 954 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990
M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 319 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 355
>gi|89041275 PREDICTED: similar to poly(A) binding protein
interacting protein 1 [Homo sapiens]
Length = 488
Score = 77.8 bits (190), Expect = 8e-14
Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)
Query: 683 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 733
P R P G LP L P+++ + +P+ ++A VL ++ + +N E
Sbjct: 87 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 145
Query: 734 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 788
S + G ED V+ LN LT P F+ ++Q + +
Sbjct: 146 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 200
Query: 789 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 848
T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+
Sbjct: 201 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 256
Query: 849 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 907
E+E +K++ + ++ R+R + F+GEL+
Sbjct: 257 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 289
Query: 908 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 953
L++ + + + + + L N +++L C +LL G L+ EK K
Sbjct: 290 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 349
Query: 954 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990
M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 350 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 386
>gi|34452730 poly(A) binding protein interacting protein 1 isoform 3
[Homo sapiens]
Length = 367
Score = 77.4 bits (189), Expect = 1e-13
Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 57/300 (19%)
Query: 711 EPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNK 770
+P+ ++A VLM++ + +N E S + G ED L V+ LN
Sbjct: 3 KPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TLSEYVQDFLNH 56
Query: 771 LT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 825
LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS A +C L
Sbjct: 57 LTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHH 116
Query: 826 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 885
+ + NFR+LLL RC+ E+E +K++
Sbjct: 117 LTISPQSG----NFRQLLLQRCRTEYE---------------------------VKDQAA 145
Query: 886 EARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLKNHDEESLE 933
+ ++ R+R + F+GEL+ L++ + + + + + L N +++L
Sbjct: 146 KGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLI 205
Query: 934 CLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 990
C +LL G L+ EK K M++ ++E ++ + S ++ ML +++LR SNW
Sbjct: 206 CAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 265
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 77.4 bits (189), Expect = 1e-13
Identities = 129/506 (25%), Positives = 176/506 (34%), Gaps = 98/506 (19%)
Query: 5 PQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQAT--QMNTPSQPRQHFYPSRAQPPSSA 62
P S P+ P PA P T + P + +NTP QP + A
Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPD--------GLVQPATPA 609
Query: 63 ASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYPV 122
A+ ++A PA PA S + P + P +Q P P P
Sbjct: 610 AATGEAAPVLTVQPAPQAPPAVSTPL--PLGLQQPQAQQPPQAP--------TPQAAAPP 659
Query: 123 QPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRI 182
Q P PG + + P + V P P +L Q+ +ER +
Sbjct: 660 QATTPQPSPGLASS----------PEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL 709
Query: 183 RDPNQGGKDITEEIMSGARTASTP---TPPQTGGGLEPQANG---------ETPQVAVIV 230
I+S A P TP G GL PQA + P A +
Sbjct: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
Query: 231 RPDDRSQGAI-----IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNL----- 280
P S ++ + D P LP P + S+P S P V P SEP L
Sbjct: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS-----RPQSVSRPPSEPPLHPCPP 824
Query: 281 --AVLSIPGDTMTTIQMSVEE--STPISRETGEPYR-LSPEPTPLAEPILEVE----VTL 331
A ++PG + Q+ V S P G P L P+ P P+ +
Sbjct: 825 PQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSST 884
Query: 332 SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES- 390
S V S +SS L APTP + ++ G S P + PE A PP P +
Sbjct: 885 SSAVASSSETSSRLPAPTP-SDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTF 943
Query: 391 -----PVPIAPTAQPEELLN----------------GAPSPP--AVDLSPVSEPEEQAKE 427
P P P QP+ LL GAP+ P + L P++ P A
Sbjct: 944 QMVTTPFPALP--QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPA--ASV 999
Query: 428 VTASMAP---PTIPSATPATAPSATS 450
+ + AP PT PS PA AP A +
Sbjct: 1000 LVSGQAPSGTPTAPSHAPAPAPMAAT 1025
Score = 66.6 bits (161), Expect = 2e-10
Identities = 142/615 (23%), Positives = 230/615 (37%), Gaps = 114/615 (18%)
Query: 4 APQST--GPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61
AP T G P A +PGL P ++ TP TP QP+ P+ PP
Sbjct: 315 APTGTPSGQPLAVAPGLGSSPLVPAPNV-ILHRTP------TPIQPK----PAGVLPPKL 363
Query: 62 AASRVQSAAPARPGPAAHVYPAG-SQVMMIPSQISYPASQGAYYIPGQG--RSTYVVPTQ 118
+ APA P Q P +++ A+ A GQ S + P
Sbjct: 364 YQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA----GQNVVLSGFPAPAL 419
Query: 119 QYPVQPGAPGFYPGASPTE-------------FGTYAGAYYPAQ----GVQQFPTGVAPA 161
Q V P GA+P + + PAQ G QF APA
Sbjct: 420 QANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPA 479
Query: 162 PVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANG 221
L Q + + + P+ GG+ I I++ A P G L P +
Sbjct: 480 VQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAG---PLSLGPVLAPHSGA 536
Query: 222 ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLA 281
+ + + P Q A+ P P++SQP+ P + + VL+ + P A
Sbjct: 537 HSAHI-LSAAPIQVGQPALF-QMPVSLAAGSLPTQSQPAPAGP--AATTVLQGVTLPPSA 592
Query: 282 VLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFS 341
V + T V+ +TP + TGE A P+L V+ P P++
Sbjct: 593 VAML-----NTPDGLVQPATPAAA-TGE-----------AAPVLTVQ-----PAPQA--- 627
Query: 342 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPE 401
P TPL P G+ + +P +P+ A PP + P P + PE
Sbjct: 628 --PPAVSTPL---------PLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP-GLASSPE 675
Query: 402 ELLNGAP---SPPAV---DLSPVSEPEEQAKEVTASMAPP-TIPSATPATAPSATSPAQE 454
+++ G P +P A+ D + P+E++++ ++ P ++P++ +AP PAQ+
Sbjct: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP---PPAQD 732
Query: 455 EEMEEEEEEEEGEAGEAGEAESEKGGEELLP---------PESTP-----IPANLSQNLE 500
+ G +A ++++ +P P S+P P S +L
Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
Query: 501 AAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVP---EVENQ---PPAGSNP 554
+ T+ P R + + + + +A P +P ++NQ PP SNP
Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPP--PQAPPTLPGIFVIQNQLGVPPPASNP 850
Query: 555 GPESEGSGVPP-RPE 568
P + G PP RP+
Sbjct: 851 APTAPGPPQPPLRPQ 865
Score = 65.9 bits (159), Expect = 3e-10
Identities = 114/502 (22%), Positives = 170/502 (33%), Gaps = 95/502 (18%)
Query: 11 PPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSSAASRVQ--- 67
PPA + G P P + P+ S Q ++ P QH P + Q A VQ
Sbjct: 427 PPATTTGAAPPQPPGALSKPM--SVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
Query: 68 --SAAPARPGP---AAHVYPAGSQVMMIP----SQISYPASQGAYYIPGQG-RSTYVVPT 117
SA PA G AA G Q++ P ++ P S G P G S +++
Sbjct: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSA 544
Query: 118 QQYPVQPGAPGFYPGASPTEFGTYAGAYYPA----------QGVQQFPTGVA----PAPV 163
P+Q G P + G+ PA QGV P+ VA P +
Sbjct: 545 A--PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGL 602
Query: 164 LMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGET 223
+ P A + ++ Q ++ + G + PPQ P
Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQA-----PTPQAAA 657
Query: 224 PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP---------------SP 268
P A +P PGL QP S +PT S
Sbjct: 658 PPQATTPQPS-----------PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706
Query: 269 SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE---STPISRETG-EPYRLSPEPTPLAEPI 324
P+ G LS+P + + ++ +TP+++ G P + +P P
Sbjct: 707 QPLSAEGPH-----LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761
Query: 325 LEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH--EPNGMVPSEDLEPEVESSPELAP 382
+ L P P S S P QAP + H H P PS P+ S P P
Sbjct: 762 IPAAAPLKGPGPSSS-PSLPHQAPLGDSPHLPSPHPTRPPSRPPSR---PQSVSRPPSEP 817
Query: 383 P--PACPSESPVPIA-------------PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 427
P P P ++P + P + P AP PP L P S+P E
Sbjct: 818 PLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT---APGPPQPPLRPQSQPPEGPLP 874
Query: 428 VTASMAPPTIPSATPATAPSAT 449
+ P + SA +++ +++
Sbjct: 875 PAPHLPPSSTSSAVASSSETSS 896
Score = 64.7 bits (156), Expect = 7e-10
Identities = 151/614 (24%), Positives = 215/614 (35%), Gaps = 95/614 (15%)
Query: 11 PPAPSPGLPQ-----PAFPPGQ--------TAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57
P AP+ LPQ PA GQ T + + P T N P A
Sbjct: 475 PGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP--LSLGPVLAP 532
Query: 58 PPSSAASRVQSAAPARPG-PAAHVYPAGSQVMMIPSQISYPASQG-AYYIPGQGRSTYVV 115
+ ++ + SAAP + G PA P +P+Q S PA G A QG +
Sbjct: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQ-SQPAPAGPAATTVLQG---VTL 588
Query: 116 PTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVA-PAPVLMNQP------ 168
P + G A+P A Q Q P V+ P P+ + QP
Sbjct: 589 PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPP 648
Query: 169 ----PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLE---PQANG 221
PQ A + T + P+ G E+I+ G ++TPT T L+ PQ
Sbjct: 649 QAPTPQAAAPPQATTPQ---PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS 705
Query: 222 ETPQVA-----------VIVRP---DDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 267
+ P A ++ P D + +A GL GP+ S++ P+ P+
Sbjct: 706 QQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQIPA 764
Query: 268 PSPVLEPG--SEPNLAVLSIPGDTM------TTIQMSVEESTP--ISRETGEPYRLSPEP 317
+P+ PG S P+L + GD+ T S S P +SR EP L P P
Sbjct: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP-PLHPCP 823
Query: 318 TPLAEPILE----VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 373
P A P L ++ L P P S + +P P + P G +P P
Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPAS--NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPP 881
Query: 374 VESSPELAPPPACPSESPVPIAPTAQ----PEELLNGAPSPPAVDLSPVSEPEEQAKEVT 429
+S +A S P P Q P + + +P+PP L V EP
Sbjct: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPT-LHLVPEPA------- 933
Query: 430 ASMAPPTIPSAT--PATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPE 487
APP P T T P P + +E + G +++ GG P
Sbjct: 934 ---APPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGII-----LQNKAGGAPAAPQT 985
Query: 488 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG--DLLDAFKEANPA-VPEV 544
ST + S + Q P A G LL A +A + +P +
Sbjct: 986 STSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL 1045
Query: 545 ENQPPAGSNPGPES 558
A S PG S
Sbjct: 1046 NVAKAASSGPGKPS 1059
Score = 38.1 bits (87), Expect = 0.069
Identities = 61/279 (21%), Positives = 90/279 (32%), Gaps = 49/279 (17%)
Query: 2 NKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPSS 61
N AP + GPP P PQ+ P P H PS +
Sbjct: 849 NPAPTAPGPPQPP-------------------LRPQSQPPEGPLPPAPHLPPSSTSSAVA 889
Query: 62 AASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQQYP 121
++S S PA P P+ Q+ +P SQG + P + ++VP P
Sbjct: 890 SSSETSSRLPA-PTPS-------------DFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP 935
Query: 122 VQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQP--PQIAPKRERKT 179
P F +P F + Q P+G+ +L N+ AP+
Sbjct: 936 PPPPPRTFQMVTTP--FPALPQPKALLERFHQVPSGI----ILQNKAGGAPAAPQTSTSL 989
Query: 180 IRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQ-ANGETPQVAVIVRPDDRSQG 238
+ P ++SG + TPT P P A G P + + +
Sbjct: 990 GPLTSP------AASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLP 1043
Query: 239 AIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSE 277
+ + GP PS Q S P L+P E
Sbjct: 1044 TLNVAKAASSGP-GKPSGLQYESKLSGLKKPPTLQPSKE 1081
Score = 33.9 bits (76), Expect = 1.3
Identities = 82/378 (21%), Positives = 126/378 (33%), Gaps = 64/378 (16%)
Query: 231 RPDD-----RSQGA-IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEP---------G 275
+PD+ RS G I A G P H P S S+P + P P L G
Sbjct: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSS--SAPGASTQPPPHLPTKLVIRHGGAG 1254
Query: 276 SEPNL-------AVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI-LEV 327
P++ ++ S + + +E P+ P + + + + ++
Sbjct: 1255 GSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQ 1314
Query: 328 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP 387
E LSK V + P+ P P + T+++ EP P + PPPA P
Sbjct: 1315 EAGLSKVVHNTALD--PVHQPPPPPA-TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371
Query: 388 SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPS 447
P L AP P + L K ++ P P TPA
Sbjct: 1372 ERKP------------LGTAPHCPRLPL---------RKTYRENVGGPGAPEGTPAGRAR 1410
Query: 448 ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQV 507
SPA + +E G E E E L P P PA + +
Sbjct: 1411 GGSPAPLP--AKVDEATSGLIRELAAVEDELYQRMLKGP--PPEPAASAAQGTGDPDWEA 1466
Query: 508 AVSVPKRRRKIKELNKKEAV--------GDLLDAFKEANPAVPEVENQP---PAGSNPGP 556
P +RRK + + +A L + + A ++ ++ P PA S P
Sbjct: 1467 PGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA 1526
Query: 557 ESEGSGVPPRPEEADETW 574
S G+ P P E +
Sbjct: 1527 ASAGTPASPPPLHRPEAY 1544
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,278,230
Number of Sequences: 37866
Number of extensions: 4655385
Number of successful extensions: 59037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 434
Number of HSP's successfully gapped in prelim test: 2065
Number of HSP's that attempted gapping in prelim test: 29736
Number of HSP's gapped (non-prelim): 20133
length of query: 1599
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1483
effective length of database: 13,855,062
effective search space: 20547056946
effective search space used: 20547056946
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.