Guide to the Human Genome
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Search of human proteins with 38156703

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38156703 microphthalmia-associated transcription factor
isoform 2 [Homo sapiens]
         (504 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38156703 microphthalmia-associated transcription factor isofo...  1004   0.0  
gi|38156705 microphthalmia-associated transcription factor isofo...   966   0.0  
gi|38156701 microphthalmia-associated transcription factor isofo...   966   0.0  
gi|38156699 microphthalmia-associated transcription factor isofo...   966   0.0  
gi|38156697 microphthalmia-associated transcription factor isofo...   810   0.0  
gi|4557755 microphthalmia-associated transcription factor isofor...   804   0.0  
gi|8659574 transcription factor E3 [Homo sapiens]                     434   e-122
gi|24307933 transcription factor EB [Homo sapiens]                    357   2e-98
gi|6912702 transcription factor EC isoform a [Homo sapiens]           284   1e-76
gi|64762402 transcription factor EC isoform b [Homo sapiens]          265   9e-71
gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens]     59   1e-08
gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens]      59   1e-08
gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens]      56   9e-08
gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens]     56   9e-08
gi|52630419 sterol regulatory element binding transcription fact...    54   3e-07
gi|22547195 sterol regulatory element binding transcription fact...    54   3e-07
gi|27477113 sterol regulatory element-binding transcription fact...    52   1e-06
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             52   2e-06
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ...    45   2e-04
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ...    45   2e-04
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ...    45   2e-04
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      44   4e-04
gi|4758010 clock [Homo sapiens]                                        43   6e-04
gi|56549696 E1A binding protein p400 [Homo sapiens]                    43   8e-04
gi|5453734 MAD4 [Homo sapiens]                                         43   8e-04
gi|31745180 aryl hydrocarbon receptor nuclear translocator-like ...    42   0.001
gi|30795240 aryl hydrocarbon receptor nuclear translocator isofo...    42   0.001
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor...    42   0.001
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro...    42   0.002
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]        42   0.002

>gi|38156703 microphthalmia-associated transcription factor isoform
           2 [Homo sapiens]
          Length = 504

 Score = 1004 bits (2595), Expect = 0.0
 Identities = 504/504 (100%), Positives = 504/504 (100%)

Query: 1   MEALRVQMFMPCSFESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQ 60
           MEALRVQMFMPCSFESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQ
Sbjct: 1   MEALRVQMFMPCSFESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQ 60

Query: 61  QQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQR 120
           QQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQR
Sbjct: 61  QQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQR 120

Query: 121 QQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGF 180
           QQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGF
Sbjct: 121 QQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGF 180

Query: 181 YKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLP 240
           YKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLP
Sbjct: 181 YKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLP 240

Query: 241 VSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERR 300
           VSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERR
Sbjct: 241 VSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERR 300

Query: 301 RRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLE 360
           RRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLE
Sbjct: 301 RRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLE 360

Query: 361 HANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADL 420
           HANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADL
Sbjct: 361 HANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADL 420

Query: 421 TCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSS 480
           TCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSS
Sbjct: 421 TCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSS 480

Query: 481 VSPGASKTSSRRSSMSMEETEHTC 504
           VSPGASKTSSRRSSMSMEETEHTC
Sbjct: 481 VSPGASKTSSRRSSMSMEETEHTC 504


>gi|38156705 microphthalmia-associated transcription factor isoform
           6 [Homo sapiens]
          Length = 495

 Score =  966 bits (2497), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 20  SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 79
           SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT
Sbjct: 11  SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 70

Query: 80  PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV 139
           PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV
Sbjct: 71  PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV 130

Query: 140 LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH 199
           LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH
Sbjct: 131 LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH 190

Query: 200 SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL 259
           SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL
Sbjct: 191 SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL 250

Query: 260 TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 319
           TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS
Sbjct: 251 TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 310

Query: 320 NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA 379
           NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA
Sbjct: 311 NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA 370

Query: 380 HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL 439
           HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL
Sbjct: 371 HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL 430

Query: 440 GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 499
           GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE
Sbjct: 431 GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 490

Query: 500 TEHTC 504
           TEHTC
Sbjct: 491 TEHTC 495


>gi|38156701 microphthalmia-associated transcription factor isoform
           3 [Homo sapiens]
          Length = 519

 Score =  966 bits (2497), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 20  SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 79
           SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT
Sbjct: 35  SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 94

Query: 80  PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV 139
           PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV
Sbjct: 95  PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV 154

Query: 140 LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH 199
           LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH
Sbjct: 155 LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH 214

Query: 200 SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL 259
           SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL
Sbjct: 215 SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL 274

Query: 260 TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 319
           TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS
Sbjct: 275 TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 334

Query: 320 NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA 379
           NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA
Sbjct: 335 NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA 394

Query: 380 HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL 439
           HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL
Sbjct: 395 HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL 454

Query: 440 GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 499
           GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE
Sbjct: 455 GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 514

Query: 500 TEHTC 504
           TEHTC
Sbjct: 515 TEHTC 519


>gi|38156699 microphthalmia-associated transcription factor isoform
           1 [Homo sapiens]
          Length = 520

 Score =  966 bits (2497), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 20  SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 79
           SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT
Sbjct: 36  SSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQT 95

Query: 80  PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV 139
           PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV
Sbjct: 96  PAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQV 155

Query: 140 LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH 199
           LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH
Sbjct: 156 LSLPCPNQPGDHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTH 215

Query: 200 SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL 259
           SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL
Sbjct: 216 SRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGL 275

Query: 260 TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 319
           TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS
Sbjct: 276 TISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKS 335

Query: 320 NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA 379
           NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA
Sbjct: 336 NDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARA 395

Query: 380 HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL 439
           HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL
Sbjct: 396 HGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNL 455

Query: 440 GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 499
           GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE
Sbjct: 456 GTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 515

Query: 500 TEHTC 504
           TEHTC
Sbjct: 516 TEHTC 520


>gi|38156697 microphthalmia-associated transcription factor isoform
           5 [Homo sapiens]
          Length = 413

 Score =  810 bits (2093), Expect = 0.0
 Identities = 402/403 (99%), Positives = 403/403 (100%)

Query: 102 KVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSA 161
           +VQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSA
Sbjct: 11  QVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSA 70

Query: 162 PNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSY 221
           PNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSY
Sbjct: 71  PNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSY 130

Query: 222 NEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEA 281
           NEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEA
Sbjct: 131 NEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEA 190

Query: 282 RALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRK 341
           RALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRK
Sbjct: 191 RALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRK 250

Query: 342 LQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIK 401
           LQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIK
Sbjct: 251 LQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIK 310

Query: 402 QEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLED 461
           QEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLED
Sbjct: 311 QEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLED 370

Query: 462 ILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 504
           ILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC
Sbjct: 371 ILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 413


>gi|4557755 microphthalmia-associated transcription factor isoform 4
           [Homo sapiens]
          Length = 419

 Score =  804 bits (2076), Expect = 0.0
 Identities = 402/409 (98%), Positives = 403/409 (98%), Gaps = 6/409 (1%)

Query: 102 KVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSA 161
           +VQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSA
Sbjct: 11  QVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSA 70

Query: 162 PNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSY 221
           PNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSY
Sbjct: 71  PNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSY 130

Query: 222 NEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT---- 277
           NEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELT    
Sbjct: 131 NEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIF 190

Query: 278 --ESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKAS 335
             ESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKAS
Sbjct: 191 PTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKAS 250

Query: 336 VDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDL 395
           VDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDL
Sbjct: 251 VDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDL 310

Query: 396 VNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKM 455
           VNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKM
Sbjct: 311 VNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKM 370

Query: 456 GSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 504
           GSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC
Sbjct: 371 GSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC 419


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score =  434 bits (1116), Expect = e-122
 Identities = 269/534 (50%), Positives = 328/534 (61%), Gaps = 105/534 (19%)

Query: 19  LSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ 78
           LS++   G S+ P  SSS +SR+LLRQQLMR Q QEQERRE++++  AA F     P   
Sbjct: 92  LSASSSAGGSRTPAMSSSSSSRVLLRQQLMRAQAQEQERRERREQAAAAPFPS---PAPA 148

Query: 79  TPAINV------SVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLA 132
           +PAI+V          + P   QVP EVLKVQTHLENPT+YH+QQA+RQQVKQYLSTTL 
Sbjct: 149 SPAISVVGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLG 208

Query: 133 NKHANQVLSLPCPNQPGDHVMPPVPG----------SSAPNSPMAMLTLNSNCEKEGFYK 182
            K A+Q L+ P    PG     P+P            SAPNSPMA+LT+ S+ EKE    
Sbjct: 209 PKLASQALTPP----PGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKE---- 260

Query: 183 FEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMD---PALQMANTL 239
                                   +DDVID+IISLESSYN+E+L  +      LQ+ +TL
Sbjct: 261 ------------------------IDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTL 296

Query: 240 PVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIER 299
           PVSGNL+D+Y +QG+  P +T+SNSCPA LPNIKRE++E+EA+AL KERQKKDNHNLIER
Sbjct: 297 PVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIER 356

Query: 300 RRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKL 359
           RRRFNINDRIKELGTLIPKS+DP+MRWNKGTILKASVDYIRKLQ+EQQR+K+LE+RQ+ L
Sbjct: 357 RRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSL 416

Query: 360 EHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHAD 419
           E ANR L LRIQELE+QA+ HGL + P+ GL S               + S  L     D
Sbjct: 417 EQANRSLQLRIQELELQAQIHGLPVPPTPGLLS-----------LATTSASDSLKPEQLD 465

Query: 420 LTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSK--------------------- 458
           +      +   G  TF  ++G G   N  +  P    S                      
Sbjct: 466 I----EEEGRPGAATF--HVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGDLGDPFHL 519

Query: 459 -LEDILMDD-----------TLSPV-GVTDPLLSSVSPGASKTSSRRSSMSMEE 499
            LEDILM++            LSP+   +DPLLSSVSP  SK SSRRSS SMEE
Sbjct: 520 GLEDILMEEEEGVVGGLSGGALSPLRAASDPLLSSVSPAVSKASSRRSSFSMEE 573


>gi|24307933 transcription factor EB [Homo sapiens]
          Length = 476

 Score =  357 bits (915), Expect = 2e-98
 Identities = 230/509 (45%), Positives = 300/509 (58%), Gaps = 83/509 (16%)

Query: 37  MTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ-------TPAINVSVPTT 89
           M SRI LR QLMREQ Q++E+RE+ Q+     +MQQ+    Q       TPAIN   P  
Sbjct: 1   MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINT--PVH 58

Query: 90  LPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------P 143
             S   VP EVLKVQ++LENPT YH+QQ+Q Q+V++YLS T  NK A  +         P
Sbjct: 59  FQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPP 118

Query: 144 CPNQPG---DHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHS 200
               PG    HV+    G+SAPNSPMAML + SN E+E                      
Sbjct: 119 PAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERE---------------------- 156

Query: 201 RASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT 260
                 +DDVID+I+ L+     ++LG ++P +QM NTLP+S + +++Y +       L 
Sbjct: 157 ------LDDVIDNIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLV 205

Query: 261 --ISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK 318
              S+SCPA+L   KRELT++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK
Sbjct: 206 GVTSSSCPADLTQ-KRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPK 264

Query: 319 SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQAR 378
           +ND D+RWNKGTILKASVDYIR++Q++ Q+++ELEN  ++LE  N+ L LRIQELEMQAR
Sbjct: 265 ANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQAR 324

Query: 379 AHGLSLIPSTGLCSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCT 423
            HGL     +G+   +L  +++KQE P  E   + L              L   A L   
Sbjct: 325 VHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLP 384

Query: 424 TTLDLTDGTITFNNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSP 470
           T        + F+++L  G    E    Y  P   G            L+ +L+DD+L P
Sbjct: 385 TQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLP 444

Query: 471 VGVTDPLLSSVSPGASKTSSRRSSMSMEE 499
           +  +DPLLS++SP ASK SSRRSS SMEE
Sbjct: 445 L-ASDPLLSTMSPEASKASSRRSSFSMEE 472


>gi|6912702 transcription factor EC isoform a [Homo sapiens]
          Length = 347

 Score =  284 bits (727), Expect = 1e-76
 Identities = 171/296 (57%), Positives = 214/296 (72%), Gaps = 16/296 (5%)

Query: 207 MDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLY-GNQGLPP--PGLTISN 263
           M+DVI+DII +ESS+ EE     D  L M  TL  SG+++D+Y G QG+ P   GLT S 
Sbjct: 61  MEDVIEDIIGMESSFKEEGA---DSPLLMQRTL--SGSILDVYSGEQGISPINMGLT-SA 114

Query: 264 SCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPD 323
           SCP++LP +KRE+TE++ RALAKERQKKDNHNLIERRRR+NIN RIKELGTLIPKSNDPD
Sbjct: 115 SCPSSLP-MKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPD 173

Query: 324 MRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLS 383
           MRWNKGTILKASV+YI+ LQ+EQQRA+ELE+RQKKLE ANR LLLRIQELE+QAR HGL 
Sbjct: 174 MRWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQARTHGLP 233

Query: 384 LIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGT 443
            + S G  + DL   + KQ+   E  S D  Q    ++   + +L D  I F++ L   T
Sbjct: 234 TLASLG--TVDLGAHVTKQQSHPEQNSVDYCQQ-LTVSQGPSPELCDQAIAFSDPLSYFT 290

Query: 444 EANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEE 499
           + +  +S   K   +L+ +L+DDT+SP G TDPLLS+ SP  SK SSRRSS S ++
Sbjct: 291 DLS--FSAALKEEQRLDGMLLDDTISPFG-TDPLLSATSPAVSKESSRRSSFSSDD 343


>gi|64762402 transcription factor EC isoform b [Homo sapiens]
          Length = 318

 Score =  265 bits (676), Expect = 9e-71
 Identities = 154/262 (58%), Positives = 194/262 (74%), Gaps = 11/262 (4%)

Query: 241 VSGNLIDLY-GNQGLPP--PGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLI 297
           +SG+++D+Y G QG+ P   GLT S SCP++LP +KRE+TE++ RALAKERQKKDNHNLI
Sbjct: 61  LSGSILDVYSGEQGISPINMGLT-SASCPSSLP-MKREITETDTRALAKERQKKDNHNLI 118

Query: 298 ERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQK 357
           ERRRR+NIN RIKELGTLIPKSNDPDMRWNKGTILKASV+YI+ LQ+EQQRA+ELE+RQK
Sbjct: 119 ERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQK 178

Query: 358 KLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHH 417
           KLE ANR LLLRIQELE+QAR HGL  + S G  + DL   + KQ+   E  S D  Q  
Sbjct: 179 KLEQANRRLLLRIQELEIQARTHGLPTLASLG--TVDLGAHVTKQQSHPEQNSVDYCQQ- 235

Query: 418 ADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPL 477
             ++   + +L D  I F++ L   T+ +  +S   K   +L+ +L+DDT+SP G TDPL
Sbjct: 236 LTVSQGPSPELCDQAIAFSDPLSYFTDLS--FSAALKEEQRLDGMLLDDTISPFG-TDPL 292

Query: 478 LSSVSPGASKTSSRRSSMSMEE 499
           LS+ SP  SK SSRRSS S ++
Sbjct: 293 LSATSPAVSKESSRRSSFSSDD 314


>gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens]
          Length = 279

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 35/109 (32%), Positives = 61/109 (55%), Gaps = 9/109 (8%)

Query: 286 KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRW--NKGTILKASVDYIRKLQ 343
           ++ +++  HN +ERRRR  IN+ I +L  +IP  N  + +   +KG IL  + DYIR+L+
Sbjct: 165 RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELR 224

Query: 344 REQQRAKELENRQKKLEHANRHLLLRIQELE-------MQARAHGLSLI 385
           +  QR +E     ++L+  N  L  +I+EL+        Q + H L ++
Sbjct: 225 QTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMV 273


>gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens]
          Length = 346

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 35/109 (32%), Positives = 61/109 (55%), Gaps = 9/109 (8%)

Query: 286 KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRW--NKGTILKASVDYIRKLQ 343
           ++ +++  HN +ERRRR  IN+ I +L  +IP  N  + +   +KG IL  + DYIR+L+
Sbjct: 232 RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELR 291

Query: 344 REQQRAKELENRQKKLEHANRHLLLRIQELE-------MQARAHGLSLI 385
           +  QR +E     ++L+  N  L  +I+EL+        Q + H L ++
Sbjct: 292 QTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMV 340


>gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens]
          Length = 310

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 19/122 (15%)

Query: 278 ESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMR--WNKGTILKAS 335
           +SEA    ++ +++  HN +ERRRR  IN+ I +L  +IP  +    +   +KG IL  +
Sbjct: 188 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA 247

Query: 336 VDYIRKLQREQQRAKE---------LEN---RQKKLEHANRHLLLRIQELEMQARAHGLS 383
            DYI++L++   R  E         L+N   RQ+  +  N++LLLR      Q R HGL 
Sbjct: 248 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLR-----AQLRHHGLE 302

Query: 384 LI 385
           ++
Sbjct: 303 VV 304


>gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens]
          Length = 251

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 40/122 (32%), Positives = 65/122 (53%), Gaps = 19/122 (15%)

Query: 278 ESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMR--WNKGTILKAS 335
           +SEA    ++ +++  HN +ERRRR  IN+ I +L  +IP  +    +   +KG IL  +
Sbjct: 129 KSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKA 188

Query: 336 VDYIRKLQREQQRAKE---------LEN---RQKKLEHANRHLLLRIQELEMQARAHGLS 383
            DYI++L++   R  E         L+N   RQ+  +  N++LLLR      Q R HGL 
Sbjct: 189 CDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLR-----AQLRHHGLE 243

Query: 384 LI 385
           ++
Sbjct: 244 VV 245


>gi|52630419 sterol regulatory element binding transcription factor
           1 isoform a [Homo sapiens]
          Length = 1177

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 4/96 (4%)

Query: 272 IKRELTESEARALAKER-QKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGT 330
           I R    S+A A A+ R +K+  HN IE+R R +IND+I EL  L+  +   + + NK  
Sbjct: 335 INRLAAGSKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGT---EAKLNKSA 391

Query: 331 ILKASVDYIRKLQREQQRAKELENRQKKLEHANRHL 366
           +L+ ++DYIR LQ   Q+ K+     +   H ++ L
Sbjct: 392 VLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSL 427


>gi|22547195 sterol regulatory element binding transcription factor
           1 isoform b [Homo sapiens]
          Length = 1147

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 4/96 (4%)

Query: 272 IKRELTESEARALAKER-QKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGT 330
           I R    S+A A A+ R +K+  HN IE+R R +IND+I EL  L+  +   + + NK  
Sbjct: 305 INRLAAGSKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGT---EAKLNKSA 361

Query: 331 ILKASVDYIRKLQREQQRAKELENRQKKLEHANRHL 366
           +L+ ++DYIR LQ   Q+ K+     +   H ++ L
Sbjct: 362 VLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSL 397


>gi|27477113 sterol regulatory element-binding transcription factor
           2 [Homo sapiens]
          Length = 1141

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 29/82 (35%), Positives = 50/82 (60%), Gaps = 4/82 (4%)

Query: 286 KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQRE 345
           KE +++  HN+IE+R R +IND+I EL  L+  +   D + +K  +L+ ++DYI+ LQ+ 
Sbjct: 327 KEGERRTTHNIIEKRYRSSINDKIIELKDLVMGT---DAKMHKSGVLRKAIDYIKYLQQV 383

Query: 346 QQRAKELENRQKKLEHANRHLL 367
             + ++ EN   KL +    LL
Sbjct: 384 NHKLRQ-ENMVLKLANQKNKLL 404


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 13/101 (12%)

Query: 275 ELTESEARALAKERQK-KDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 333
           E+TE+E     + R+K ++ HN +ER R+  IN  I  +G LIP S  P ++ +K  IL 
Sbjct: 3   EMTENETPTKKQHRKKNRETHNAVERHRKKKINAGINRIGELIPCS--PALKQSKNMILD 60

Query: 334 ASVDYIRKLQRE----------QQRAKELENRQKKLEHANR 364
            +  YI +L+R+           ++A+E++  +K+LE   +
Sbjct: 61  QAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEEIQK 101



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 33/173 (19%), Positives = 66/173 (38%), Gaps = 31/173 (17%)

Query: 11   PCSFESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQF- 69
            P   E     +++H  A +  + +  ++        + ++Q Q+Q++++QQQ+ QA Q  
Sbjct: 1424 PSVAEQQQTQASQHLQALQQHVPAQGVSHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLR 1483

Query: 70   -------MQQRVPVSQTPA----------------INVSVPTTLPSATQVPMEVLKVQTH 106
                   MQ  VP +++                  + +     L   TQ     L+ + H
Sbjct: 1484 ERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHH 1543

Query: 107  LENPTKY-------HIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHV 152
              + ++        H QQ Q+Q  + + S+       N   S    N P +H+
Sbjct: 1544 GTDQSRSKTGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHHNHPQNHL 1596


>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
           isoform b [Homo sapiens]
          Length = 582

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 5/101 (4%)

Query: 270 PNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKG 329
           P+ + E TE + R     +  ++ H+ IE+RRR  +N  I EL +L+P  N    + +K 
Sbjct: 14  PHGRLEYTEHQGRI----KNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKL 69

Query: 330 TILKASVDYIRKLQREQQRAKELENRQKKL-EHANRHLLLR 369
           T+L+ +V +++ L+       E   +   L +   +HL+LR
Sbjct: 70  TVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILR 110


>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
           isoform a [Homo sapiens]
          Length = 625

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 5/101 (4%)

Query: 270 PNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKG 329
           P+ + E TE + R     +  ++ H+ IE+RRR  +N  I EL +L+P  N    + +K 
Sbjct: 57  PHGRLEYTEHQGRI----KNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKL 112

Query: 330 TILKASVDYIRKLQREQQRAKELENRQKKL-EHANRHLLLR 369
           T+L+ +V +++ L+       E   +   L +   +HL+LR
Sbjct: 113 TVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILR 153


>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
           isoform a [Homo sapiens]
          Length = 625

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 5/101 (4%)

Query: 270 PNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKG 329
           P+ + E TE + R     +  ++ H+ IE+RRR  +N  I EL +L+P  N    + +K 
Sbjct: 57  PHGRLEYTEHQGRI----KNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKL 112

Query: 330 TILKASVDYIRKLQREQQRAKELENRQKKL-EHANRHLLLR 369
           T+L+ +V +++ L+       E   +   L +   +HL+LR
Sbjct: 113 TVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILR 153


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 5/108 (4%)

Query: 15  ESLYLSSAEHPGASKPPISSSSMTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRV 74
           ES Y+   +H   +K      S+  R   ++QL+RE+ +++++ E   K Q  Q    + 
Sbjct: 542 ESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQT 601

Query: 75  PVSQTPAINVSVPTTLPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQ 122
            + Q P+ +  +PT   ++  V       Q   E P     QQ Q QQ
Sbjct: 602 GIKQLPSASTGIPTASTTSASV-----STQVEPEEPEADQHQQLQYQQ 644


>gi|4758010 clock [Homo sapiens]
          Length = 846

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 23/71 (32%), Positives = 43/71 (60%), Gaps = 3/71 (4%)

Query: 286 KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQRE 345
           K++ K+ + N  E++RR   N  IKELG+++P +     + +K T+L+ S+D++RK +  
Sbjct: 31  KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGN---ARKMDKSTVLQKSIDFLRKHKEI 87

Query: 346 QQRAKELENRQ 356
             ++   E RQ
Sbjct: 88  TAQSDASEIRQ 98


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 28/129 (21%)

Query: 46   QLMREQMQEQERREQQQKLQAAQFMQQRVPVSQTPAINVSVPTTLPSATQVPMEVLKVQT 105
            QL+R+Q Q+Q++++QQQ+ Q  Q  QQ+    Q         TT  S  QVP    ++Q 
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---------TTTTSQVQVP----QIQG 2761

Query: 106  HLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDHVMPPVPGSSAPNSP 165
              ++P           Q+K     T  +    Q   L  P QP     PP    SAP  P
Sbjct: 2762 QAQSPA----------QIKAVGKLTPEHLIKMQKQKLQMPPQP-----PPPQAQSAPPQP 2806

Query: 166  MAMLTLNSN 174
             A + + ++
Sbjct: 2807 TAQVQVQTS 2815



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 22/129 (17%)

Query: 37   MTSRILLRQQLMREQMQEQERREQ-----QQKLQAAQFM----QQRVPVSQTPAINVSVP 87
            M   + L+QQ +++Q   Q +  Q     QQK+ A Q      QQ+V  +  PA+     
Sbjct: 2926 MQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFL 2985

Query: 88   TTLPSATQVPMEVLKVQTHL-----------ENPTK--YHIQQAQRQQVKQYLSTTLANK 134
            TT  S  Q      +VQT +           + P      +  A +Q   Q ++ T A  
Sbjct: 2986 TTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATA 3045

Query: 135  HANQVLSLP 143
               QV  +P
Sbjct: 3046 AGQQVQMIP 3054


>gi|5453734 MAD4 [Homo sapiens]
          Length = 209

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 5/104 (4%)

Query: 274 RELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 333
           RE T++ A  + K    + +HN +E+ RR  +   +++L  L+P   D   R    ++LK
Sbjct: 39  REKTKA-AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLK 96

Query: 334 ASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 377
            +  +I+KL+ + +RA  +   +++L+  +R L  R+++L +Q+
Sbjct: 97  RAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137


>gi|31745180 aryl hydrocarbon receptor nuclear translocator-like 2
           [Homo sapiens]
          Length = 636

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 26/88 (29%), Positives = 48/88 (54%), Gaps = 1/88 (1%)

Query: 286 KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQRE 345
           K +  ++ H+  E+RRR  +N+ I+EL  +IP+ N    + +K T+L+ +V ++R L+  
Sbjct: 104 KMKAFREAHSQTEKRRRDKMNNLIEELSAMIPQCNPMARKLDKLTVLRMAVQHLRSLKGL 163

Query: 346 QQRAKELENRQKKL-EHANRHLLLRIQE 372
                    R   L ++  RHL+L+  E
Sbjct: 164 TNSYVGSNYRPSFLQDNELRHLILKTAE 191


>gi|30795240 aryl hydrocarbon receptor nuclear translocator isoform
           2 [Homo sapiens]
          Length = 328

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/67 (32%), Positives = 40/67 (59%)

Query: 277 TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASV 336
           ++ E  +  KER  ++NH+ IERRRR  +   I EL  ++P  +    + +K TIL+ +V
Sbjct: 77  SDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAV 136

Query: 337 DYIRKLQ 343
            +++ L+
Sbjct: 137 SHMKSLR 143


>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
           [Homo sapiens]
          Length = 789

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/67 (32%), Positives = 40/67 (59%)

Query: 277 TESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASV 336
           ++ E  +  KER  ++NH+ IERRRR  +   I EL  ++P  +    + +K TIL+ +V
Sbjct: 77  SDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAV 136

Query: 337 DYIRKLQ 343
            +++ L+
Sbjct: 137 SHMKSLR 143


>gi|19923312 v-myc myelocytomatosis viral related oncogene,
           neuroblastoma derived [Homo sapiens]
          Length = 464

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 31/122 (25%), Positives = 63/122 (51%), Gaps = 11/122 (9%)

Query: 251 NQGLPPPGLTISNSCPANLPNI--KRELTESEARALAKERQKKDNHNLIERRRRFNINDR 308
           ++  PP     S + P  L ++   +  + S   + +++ +++ NHN++ER+RR ++   
Sbjct: 341 SEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSS 400

Query: 309 IKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQR----AKELENRQ----KKLE 360
              L   +P+    + +  K  ILK + +Y+  LQ E+ +     ++L+ RQ    KK+E
Sbjct: 401 FLTLRDHVPELVKNE-KAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIE 459

Query: 361 HA 362
           HA
Sbjct: 460 HA 461


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 37/179 (20%)

Query: 249 YGNQGLPPPGLTISNSCPAN---------------LPNIKRELTESEARALAK------E 287
           Y +   PPP      + P++               LP        SE R+  +       
Sbjct: 172 YSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDH 231

Query: 288 RQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRW----NKGTILKASVDYIRKLQ 343
           R +  +H   ER R  +  +R +      P     D R+    ++G        Y R  +
Sbjct: 232 RHRDHSHGRGERHRSLDRRERGRS-----PDRRRQDSRYRSDYDRGRTPSRHRSYERSRE 286

Query: 344 REQQRAKELENRQK-KLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIK 401
           RE++R +  +NR+   LE + +      +E +   R++GLS++P    C+P+L   IIK
Sbjct: 287 RERERHRHRDNRRSPSLERSYK------KEYKRSGRSYGLSVVPEPAGCTPELPGEIIK 339


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,852,772
Number of Sequences: 37866
Number of extensions: 933032
Number of successful extensions: 7360
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 194
Number of HSP's that attempted gapping in prelim test: 5395
Number of HSP's gapped (non-prelim): 1084
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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