Guide to the Human Genome
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Name: PHLPP1 Sequence: fasta or formatted (1205aa) NCBI GI: 37221175
Description:

PH domain and leucine rich repeat protein phosphatase

Referenced in:

Leucine-rich Repeat Family
Serine / Threonine Protein Phosphatases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         72           3
 C cysteine            3.1         37           3
 D aspartate           4.9         59           2
 E glutamate           7.3         88           3
 F phenylalanine       3.0         36           2
 G glycine             5.1         61           2
 H histidine           2.9         35           2
 I isoleucine          4.2         51           2
 K lysine              4.8         58           2
 L leucine            12.7        153           2
 M methionine          2.1         25           1
 N asparagine          5.3         64           2
 P proline             6.6         79           5
 Q glutamine           5.0         60           6
 R arginine            4.5         54           3
 S serine              8.8        106           4
 T threonine           4.2         51           2
 V valine              7.1         85           3
 W tryptophan          0.4          5           1
 Y tyrosine            2.2         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   PH domain and leucine rich repeat protein phosphatas... 
PHLPP2                0.528   PH domain and leucine rich repeat protein phosphatas...
SHOC2                 0.050   soc-2 suppressor of clear homolog 
LOC401387             0.045   leucine-rich repeat and death domain-containing pro...
LRRC40                0.043   leucine rich repeat containing 40 
LRRIQ4                0.035   leucine-rich repeats and IQ motif containing 4 [Hom...
LRRC1                 0.035   leucine rich repeat containing 1 
ERBB2IP               0.034   ERBB2 interacting protein isoform 7 
ERBB2IP               0.034   ERBB2 interacting protein isoform 2 
LGR6                  0.030   leucine-rich repeat-containing G protein-coupled rec...
SCRIB                 0.029   scribble isoform b 
SCRIB                 0.029   scribble isoform a 
LGR6                  0.029   leucine-rich repeat-containing G protein-coupled rec...
LRRK2                 0.029   leucine-rich repeat kinase 2 
MFHAS1                0.029   malignant fibrous histiocytoma amplified sequence 1...
IGFALS                0.028   insulin-like growth factor binding protein, acid la...
IGFALS                0.028   insulin-like growth factor binding protein, acid labi...
FLII                  0.028   flightless I homolog 
LRRC7                 0.028   leucine rich repeat containing 7 
LGR5                  0.026   leucine-rich repeat-containing G protein-coupled rece...
LRRC8C                0.026   leucine rich repeat containing 8 family, member C [H...
PODN                  0.026   podocan 
PODNL1                0.025   podocan-like 1 isoform 2 
PODNL1                0.025   podocan-like 1 isoform 1 
LGR4                  0.025   leucine-rich repeat-containing G protein-coupled re...
GP5                   0.025   glycoprotein V (platelet) 
LRRC8E                0.025   leucine rich repeat containing 8 family, member E [H...
TLR7                  0.024   toll-like receptor 7 
LRRC8D                0.024   leucine rich repeat containing 8 family, member D [...
LRRC8D                0.024   leucine rich repeat containing 8 family, member D [H...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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