Guide to the Human Genome
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Name: LRRK2 Sequence: fasta or formatted (2527aa) NCBI GI: 171846278
Description:

leucine-rich repeat kinase 2

Referenced in:

Leucine-rich Repeat Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0        127           2
 C cysteine            2.5         64           2
 D aspartate           4.9        123           2
 E glutamate           7.3        184           3
 F phenylalanine       3.8         96           2
 G glycine             4.7        119           3
 H histidine           3.2         80           2
 I isoleucine          6.3        160           3
 K lysine              7.0        176           3
 L leucine            14.1        356           4
 M methionine          2.8         70           2
 N asparagine          5.1        128           2
 P proline             3.7         94           2
 Q glutamine           4.2        105           2
 R arginine            4.1        104           2
 S serine              8.1        205           3
 T threonine           3.8         96           2
 V valine              6.3        160           3
 W tryptophan          1.0         26           1
 Y tyrosine            2.1         54           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   leucine-rich repeat kinase 2 
LRRK1                 0.079   leucine-rich repeat kinase 1 
MFHAS1                0.020   malignant fibrous histiocytoma amplified sequence 1...
MAP3K9                0.017   mitogen-activated protein kinase kinase kinase 9 [Ho...
MAP3K7                0.016   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.016   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.016   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.016   mitogen-activated protein kinase kinase kinase 7 isof...
SHOC2                 0.016   soc-2 suppressor of clear homolog 
MAP3K10               0.016   mitogen-activated protein kinase kinase kinase 10 [H...
MATK                  0.016   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.016   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.016   megakaryocyte-associated tyrosine kinase isoform a [...
KIAA1804              0.015   mixed lineage kinase 4 
TNNI3K                0.015   TNNI3 interacting kinase isoform b 
TNNI3K                0.015   TNNI3 interacting kinase isoform a 
PRKD1                 0.015   protein kinase D1 
PRKD3                 0.014   protein kinase D3 
PRKD2                 0.014   protein kinase D2 isoform B 
PRKD2                 0.014   protein kinase D2 isoform A 
PRKD2                 0.014   protein kinase D2 isoform A 
PRKD2                 0.014   protein kinase D2 isoform A 
TEK                   0.014   TEK tyrosine kinase, endothelial precursor 
CAMK4                 0.014   calcium/calmodulin-dependent protein kinase IV 
SCRIB                 0.014   scribble isoform b 
SCRIB                 0.014   scribble isoform a 
PHLPP1                0.014   PH domain and leucine rich repeat protein phosphatas...
MAP3K11               0.014   mitogen-activated protein kinase kinase kinase 11 [Ho...
ERBB2IP               0.013   ERBB2 interacting protein isoform 7 
ERBB2IP               0.013   ERBB2 interacting protein isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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