Guide to the Human Genome
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Search of human proteins with 34916028

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
         (509 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34916028 solute carrier family 16 (monocarboxylic acid transp...  1033   0.0  
gi|41327156 solute carrier family 16 (monocarboxylic acid transp...   277   1e-74
gi|4759114 solute carrier family 16, member 4 [Homo sapiens]          190   2e-48
gi|157041233 solute carrier family 16 (monocarboxylic acid trans...   176   6e-44
gi|40789261 solute carrier family 16, member 6 [Homo sapiens]         173   4e-43
gi|115583685 solute carrier family 16, member 1 [Homo sapiens]        150   2e-36
gi|24431958 solute carrier family 16, member 7 [Homo sapiens]         147   2e-35
gi|42475555 monocarboxylate transporter 13 [Homo sapiens]             144   2e-34
gi|109288010 solute carrier family 16, member 3 [Homo sapiens]        143   4e-34
gi|109288012 solute carrier family 16, member 3 [Homo sapiens]        143   4e-34
gi|4759112 solute carrier family 16, member 3 [Homo sapiens]          143   4e-34
gi|114796626 solute carrier family 16, member 8 [Homo sapiens]        135   1e-31
gi|4759116 solute carrier family 16, member 5 [Homo sapiens]          132   6e-31
gi|23503293 solute carrier family 16, member 11 [Homo sapiens]        131   2e-30
gi|18699730 solute carrier family 16, member 10 [Homo sapiens]        116   6e-26
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]          101   1e-21
gi|169217968 PREDICTED: similar to solute carrier family 16, mem...    96   8e-20
gi|42476325 solute carrier family 18 (vesicular monoamine), memb...    40   0.004
gi|16445357 hypothetical protein LOC116843 [Homo sapiens]              38   0.019
gi|215272392 solute carrier family 18 (vesicular monoamine), mem...    37   0.056
gi|215272390 solute carrier family 18 (vesicular monoamine), mem...    37   0.056
gi|208879454 solute carrier family 18 (vesicular monoamine), mem...    37   0.056
gi|4506987 solute carrier family 18 (vesicular monoamine), membe...    37   0.056
gi|55749589 solute carrier family 6, member 16 [Homo sapiens]          35   0.12 
gi|32483369 origin recognition complex, subunit 3 isoform 1 [Hom...    35   0.16 
gi|32483367 origin recognition complex, subunit 3 isoform 2 [Hom...    35   0.16 
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]           35   0.16 
gi|166064062 tumor suppressing subtransferable candidate 5 [Homo...    35   0.21 
gi|166064060 tumor suppressing subtransferable candidate 5 [Homo...    35   0.21 
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo...    34   0.28 

>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG 60
           MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG
Sbjct: 1   MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG 60

Query: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120
           VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL
Sbjct: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120

Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180
           YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN
Sbjct: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180

Query: 181 ILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRI 240
           ILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRI
Sbjct: 181 ILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRI 240

Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300
           TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL
Sbjct: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300

Query: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLL 360
           FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLL
Sbjct: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLL 360

Query: 361 GILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTT 420
           GILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTT
Sbjct: 361 GILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTT 420

Query: 421 KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480
           KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL
Sbjct: 421 KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480

Query: 481 AALPSWDTCNKQLPKPAPTTFLYKVASNV 509
           AALPSWDTCNKQLPKPAPTTFLYKVASNV
Sbjct: 481 AALPSWDTCNKQLPKPAPTTFLYKVASNV 509


>gi|41327156 solute carrier family 16 (monocarboxylic acid
           transporters), member 14 [Homo sapiens]
          Length = 510

 Score =  277 bits (709), Expect = 1e-74
 Identities = 164/482 (34%), Positives = 256/482 (53%), Gaps = 17/482 (3%)

Query: 3   LKKSP--DGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG 60
           LK  P  DGGW W++V  SF    L  GS +A+GVL +EWL+ F + +G TAWV SL+ G
Sbjct: 22  LKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMG 81

Query: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120
           + L+  P   L +++ G R   I  G + + G +LS++A N+++LF ++G+  GLG G+ 
Sbjct: 82  ITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMA 141

Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180
           Y   V +  +YF  RR LA GL +TG+  G F+   L + L   YG    +LI GA++LN
Sbjct: 142 YLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLN 201

Query: 181 ILACGSLMRPLQSSDCPL-PKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCR 239
           +  CG+LMRPL     P  P +     LP           +  E++    +   +EEK  
Sbjct: 202 LCVCGALMRPLSPGKNPNDPGEKDVRGLP----------AHSTESVKSTGQQGRTEEKDG 251

Query: 240 ITLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVA 299
             L N +   D    + P     ++     + +   ++   ++ K     Y  Y G T +
Sbjct: 252 -GLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFG-TAS 309

Query: 300 LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKL 358
           LF N++F A FI   LF    F  P + + ++    N+ E+  + PL SII I+   GK+
Sbjct: 310 LFTNRMFVA-FIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKV 368

Query: 359 LLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYV 418
           +LG++AD   I+   +++     + L++  +P   +Y  LA++  ++GF +G +S+ P V
Sbjct: 369 ILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVV 428

Query: 419 TTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFIL 478
           T   VGIE LA+AYGI++   G+   LGPP  GW YD TQ YD +FY  G   ++G   L
Sbjct: 429 TEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFL 488

Query: 479 LL 480
           L+
Sbjct: 489 LI 490


>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
          Length = 487

 Score =  190 bits (483), Expect = 2e-48
 Identities = 129/487 (26%), Positives = 223/487 (45%), Gaps = 49/487 (10%)

Query: 5   KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64
           K+ DGGWGW+IV   FL      G      + ++ + + F     +  W+GS+ S +   
Sbjct: 13  KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72

Query: 65  ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124
           A P+ ++     G +  +I   F+V GG ++SS+A +I FL  + G++ GLG   LY   
Sbjct: 73  AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132

Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184
             +T +YF  R  L+  +  +G  +  F+ A   + L++ Y   G L++ GA+ALN++  
Sbjct: 133 AVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191

Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKC----RI 240
             L+RP+                 +  S   +KG +L  +     +++++E  C      
Sbjct: 192 SMLLRPIHIKS-------------ENNSGIKDKGSSLSAH---GPEAHATETHCHETEES 235

Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYK--------KKVAEQ-----TYFCKQLAKRKW 287
           T+ +   ++  L  KN TV+  +  E Y          K  E+     ++ CKQL     
Sbjct: 236 TIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLF---- 291

Query: 288 QLYKNYCGETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLIS 347
                     ++LF+N  F     + LL  +  F P+  +   A++  +   +    L+S
Sbjct: 292 ---------DISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMD-ASYLVS 341

Query: 348 IIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGF 407
           + GI+  V +++ G +AD  WI   + + + LI+ G+     P A ++  L   +     
Sbjct: 342 VAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAI 401

Query: 408 LTGNW-SIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYF 466
             G + ++   V         +    G+  FFAG+    GPPI GW YD+TQTY+ +FYF
Sbjct: 402 FAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYF 461

Query: 467 SGFCVLL 473
           SG C LL
Sbjct: 462 SGICYLL 468


>gi|157041233 solute carrier family 16 (monocarboxylic acid
           transporters), member 12 [Homo sapiens]
          Length = 486

 Score =  176 bits (445), Expect = 6e-44
 Identities = 131/481 (27%), Positives = 220/481 (45%), Gaps = 65/481 (13%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGW+IV   FL           + + ++E+   F +   +TAW+ S+   V +L +
Sbjct: 13  PDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCA 72

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           P+ S+  +    +   +  G + + GL+LSSFA ++  L+ + G++ GLG  L Y+  + 
Sbjct: 73  PLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIA 132

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
           +  +YF  R+ LA G+  +GS +G FI A + ++L+E +   G LLI+G   LN+  CG+
Sbjct: 133 MVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGA 192

Query: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246
           LMRP+                             L+E+    ++++     CR       
Sbjct: 193 LMRPI----------------------------TLKEDHTTPEQNH----VCRT------ 214

Query: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306
            +++ +   +P  + TKE          QT  C         L + Y    ++ F     
Sbjct: 215 -QKEDIKRVSPYSSLTKE--------WAQTCLC-------CCLQQEYSFLLMSDFVVLAV 258

Query: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366
           S LF+A      G  P  + +   A S  V  ++    L+SI+G++  +G +  G L D 
Sbjct: 259 SVLFMA-----YGCSPLFVYLVPYALSVGVSHQQAAF-LMSILGVIDIIGNITFGWLTDR 312

Query: 367 KWINTLYLYVATLIIMGL-ALC--AIPFAKSYVTLALLSGILGFLTGNW-SIFPYVTTKT 422
           + +   Y YV  L  +G+  LC   +P  +S   L   S   G+  G + ++ P VTT+ 
Sbjct: 313 RCLKN-YQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEI 371

Query: 423 VGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAA 482
           VG   L+ A G++ F   +   + PPI G   D T +Y  AF   GF ++    +L  A 
Sbjct: 372 VGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFAR 431

Query: 483 L 483
           L
Sbjct: 432 L 432


>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
          Length = 523

 Score =  173 bits (438), Expect = 4e-43
 Identities = 128/479 (26%), Positives = 222/479 (46%), Gaps = 32/479 (6%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGW +    F  +   YG     GV + + +D+F E   + +W+ S+   V   ++
Sbjct: 19  PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSA 78

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           P+ ++  + FG R V +  G +V+ G++ +SF+  +  ++ + GI+ GLG    +  TVT
Sbjct: 79  PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
           I  QYF  RR +   + STG    +F +A     L E  G    LL VG L LNI+  G+
Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198

Query: 187 LMRPLQSSDCPLPKKIAPEDLPD-KYSIYNEKGKNLEENINILDKSYSSEEKCRITLANG 245
           L+RP+       PK +  E+  + +Y + NEK +   ++I+   +  +S +         
Sbjct: 199 LLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNV------- 251

Query: 246 DWKQDSLLHKNPTVTHTK-EPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNK 304
                      PT T+ + EP+   ++V  +T    + +++K  L         ++ K K
Sbjct: 252 -----------PTHTNLELEPKADMQQVLVKT--SPRPSEKKAPLL------DFSILKEK 292

Query: 305 VFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILA 364
            F    +  L   +G F PSL +  +  S  + ++     L+S + I    G++  G + 
Sbjct: 293 SFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAF-LLSTMAIAEVFGRIGAGFVL 351

Query: 365 DFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLT---GNWSIFPYVTTK 421
           + + I  +Y+ +  +I++ ++L A  FA  +  L   S   GF+    G   I       
Sbjct: 352 NREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDD 411

Query: 422 TVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480
            VGIEK++ A G+ +F   +    GPP+ G   D ++ Y  AFY     + L    L L
Sbjct: 412 VVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLAL 470


>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
          Length = 500

 Score =  150 bits (380), Expect = 2e-36
 Identities = 125/478 (26%), Positives = 204/478 (42%), Gaps = 56/478 (11%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGW +V  +F++    Y  P ++ V + E    F     + +W+ S+   V     
Sbjct: 14  PDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGG 73

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           P+ S+ V+ +G+R V I  G +   GL+ +SF   +  L+   G++ GLG        +T
Sbjct: 74  PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
           +  +YF  RR LA GL   GS V L   A L ++    +G  G  LI+G L LN    G+
Sbjct: 134 MIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGA 193

Query: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246
           LMRP+     P P K                GK         DKS +S EK         
Sbjct: 194 LMRPIG----PKPTK---------------AGK---------DKSKASLEKA----GKSG 221

Query: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306
            K+D  LH   T    + P+  K+ V              +Q    +   T  LF ++ F
Sbjct: 222 VKKD--LHDANTDLIGRHPKQEKRSV--------------FQTINQFLDLT--LFTHRGF 263

Query: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366
                  ++   G F P + +    +S +   E+    L+SI+  +  V +  +G++A+ 
Sbjct: 264 LLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF-LLSILAFVDMVARPSMGLVANT 322

Query: 367 KWI--NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW--SIFPYVTTKT 422
           K I     Y + A+++  G+     P + +YV   + +G  GF  G W  S+        
Sbjct: 323 KPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFG-WLSSVLFETLMDL 381

Query: 423 VGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480
           VG ++ + A G++         LGPP++G   D    Y   ++  G  +++ G  L +
Sbjct: 382 VGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFI 439


>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score =  147 bits (372), Expect = 2e-35
 Identities = 120/477 (25%), Positives = 195/477 (40%), Gaps = 70/477 (14%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGW++V  +F++    Y  P AV V + E    F     + AW+ S+   V     
Sbjct: 14  PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           PV S+ V+ +G+RPV I  G +   G++L+SF+ ++  L+ + G + GLG        +T
Sbjct: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
           I  +YF  +R +A GL   GS V L   A   + L   +G  G  LI+G+L LN    GS
Sbjct: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193

Query: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246
           LM           + + P     K    N+ GK  +++                      
Sbjct: 194 LM-----------RPLGPNQTTSKSK--NKTGKTEDDS---------------------- 218

Query: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306
                             P+  K K            K  W+    Y     +LFK++ F
Sbjct: 219 -----------------SPKKIKTK------------KSTWEKVNKYLD--FSLFKHRGF 247

Query: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366
                  ++  +G F P + +   A+   + E      L+S++  +    +  +G++A+ 
Sbjct: 248 LIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF-LLSVMAFVDMFARPSVGLIANS 306

Query: 367 KWINTLYLYVATLIIMGLALCAI--PFAKSYVTLALLSGILGFLTGNWSIFPYVT-TKTV 423
           K+I     Y  +  IM   +C +  P A+ Y +L L +   G   G+ S   + T    V
Sbjct: 307 KYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLV 366

Query: 424 GIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480
           G  + + A G++         LGPP+ G   D T  Y   +   G  V+     LL+
Sbjct: 367 GAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI 423


>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
          Length = 426

 Score =  144 bits (362), Expect = 2e-34
 Identities = 72/191 (37%), Positives = 110/191 (57%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGWV+V  +F    L +G   + GV ++E++ AF E   + +W+ S+   V    S
Sbjct: 8   PDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGS 67

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           PV S   + FG RPV +  G + A G++L+SFA ++  L+ S G++ G G  L +  T+ 
Sbjct: 68  PVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLA 127

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
               YF  RR LA GL  TG  +  F +A   + L+  Y   G LL+V AL+L+++ACG+
Sbjct: 128 CLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGA 187

Query: 187 LMRPLQSSDCP 197
           L+RP   ++ P
Sbjct: 188 LLRPPSLAEDP 198



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 48/186 (25%), Positives = 85/186 (45%), Gaps = 4/186 (2%)

Query: 296 ETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMP-LISIIGIMTA 354
           +  +L  +  F    +A+ L + G F P L +  VA   ++  +      L+S++ I   
Sbjct: 206 QLTSLLHHGPFLRYTVALTLINTGYFIPYLHL--VAHLQDLDWDPLPAAFLLSVVAISDL 263

Query: 355 VGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSI 414
           VG+++ G L D        L +    + G++L   P A++   L  L+   GF +G  + 
Sbjct: 264 VGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAP 323

Query: 415 FPY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLL 473
             + V  + +G  ++    G+L     +G  LGPP+ G+  D T  Y  +F  +G  +L 
Sbjct: 324 LAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLS 383

Query: 474 GGFILL 479
           G  ILL
Sbjct: 384 GSGILL 389


>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  143 bits (360), Expect = 4e-34
 Identities = 75/214 (35%), Positives = 116/214 (54%)

Query: 5   KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64
           K+PDGGWGW ++F  F+     Y  P AV V + E +  FG G   TAW+ S+   +   
Sbjct: 14  KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73

Query: 65  ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124
             P+CS+CV+ FG RPV +  G   + G++ +SF  +I  ++ + G++ GLG  L +  +
Sbjct: 74  TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133

Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184
           + +  +YF  RR +A GL + GS V L   + L ++L + YG  G  LI+G L LN   C
Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193

Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218
            +LMRPL  +  P      P       S++ ++G
Sbjct: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
           +++F+++ F    +A  +  +G F P + +   A+   V + +    L++I+G +    +
Sbjct: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278

Query: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415
              G +A    +   ++YL+  ++   GLA  A   A  Y  L +     G   G     
Sbjct: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338

Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
            + V    VG  K + A G+++    +   +GPP  G   D T  Y   F  +G  VL  
Sbjct: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398

Query: 475 GFILLLAALPSWDTCNKQLPK-PAP 498
             ILLL        C ++ PK P P
Sbjct: 399 SLILLLGNF----FCIRKKPKEPQP 419


>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  143 bits (360), Expect = 4e-34
 Identities = 75/214 (35%), Positives = 116/214 (54%)

Query: 5   KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64
           K+PDGGWGW ++F  F+     Y  P AV V + E +  FG G   TAW+ S+   +   
Sbjct: 14  KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73

Query: 65  ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124
             P+CS+CV+ FG RPV +  G   + G++ +SF  +I  ++ + G++ GLG  L +  +
Sbjct: 74  TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133

Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184
           + +  +YF  RR +A GL + GS V L   + L ++L + YG  G  LI+G L LN   C
Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193

Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218
            +LMRPL  +  P      P       S++ ++G
Sbjct: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
           +++F+++ F    +A  +  +G F P + +   A+   V + +    L++I+G +    +
Sbjct: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278

Query: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415
              G +A    +   ++YL+  ++   GLA  A   A  Y  L +     G   G     
Sbjct: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338

Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
            + V    VG  K + A G+++    +   +GPP  G   D T  Y   F  +G  VL  
Sbjct: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398

Query: 475 GFILLLAALPSWDTCNKQLPK-PAP 498
             ILLL        C ++ PK P P
Sbjct: 399 SLILLLGNF----FCIRKKPKEPQP 419


>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score =  143 bits (360), Expect = 4e-34
 Identities = 75/214 (35%), Positives = 116/214 (54%)

Query: 5   KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64
           K+PDGGWGW ++F  F+     Y  P AV V + E +  FG G   TAW+ S+   +   
Sbjct: 14  KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73

Query: 65  ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124
             P+CS+CV+ FG RPV +  G   + G++ +SF  +I  ++ + G++ GLG  L +  +
Sbjct: 74  TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133

Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184
           + +  +YF  RR +A GL + GS V L   + L ++L + YG  G  LI+G L LN   C
Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193

Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218
            +LMRPL  +  P      P       S++ ++G
Sbjct: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
           +++F+++ F    +A  +  +G F P + +   A+   V + +    L++I+G +    +
Sbjct: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278

Query: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415
              G +A    +   ++YL+  ++   GLA  A   A  Y  L +     G   G     
Sbjct: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338

Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
            + V    VG  K + A G+++    +   +GPP  G   D T  Y   F  +G  VL  
Sbjct: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398

Query: 475 GFILLLAALPSWDTCNKQLPK-PAP 498
             ILLL        C ++ PK P P
Sbjct: 399 SLILLLGNF----FCIRKKPKEPQP 419


>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
          Length = 504

 Score =  135 bits (339), Expect = 1e-31
 Identities = 70/184 (38%), Positives = 105/184 (57%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGWV++   F+     YG P AV V +   +  F  G   TAWV S+   +     
Sbjct: 13  PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTG 72

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           PV S+ V+ FG RPV +  G + + G++L+SFA  +  L+ + G++ GLG  L +  ++ 
Sbjct: 73  PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
           +   YF+ RR LA GL + GS V L   + L + L+E +G  G  L++G L L+  ACG+
Sbjct: 133 MLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGA 192

Query: 187 LMRP 190
           +MRP
Sbjct: 193 VMRP 196



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 9/205 (4%)

Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
           +A+  ++ F+   +   L  +G F P++L+ + A+ + V + +    L+SI+G +  V +
Sbjct: 245 LAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAF-LLSIVGFVDIVAR 303

Query: 358 LLLGILADFKWI--NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415
              G LA    +  +  YL+   L+  GL   +   A+SY  L       G   G     
Sbjct: 304 PACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGAL 363

Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
            + V    VG  +   A G+++        +GPP  G   D  + Y+I FY +G  V L 
Sbjct: 364 QFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALA 423

Query: 475 GFILLLAALPSWDTCNKQLPKPAPT 499
           G  + +A       C  +  K AP+
Sbjct: 424 GVFMAVAT-----NCCLRCAKAAPS 443


>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
          Length = 505

 Score =  132 bits (333), Expect = 6e-31
 Identities = 66/197 (33%), Positives = 109/197 (55%)

Query: 8   DGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASP 67
           DG W WV++  + +TQ L  G P  +G+ + E    F     +T+W  S+ + V  +A P
Sbjct: 9   DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGP 68

Query: 68  VCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTI 127
           +CS+ V  FG R   +  G + + G++ SSF+ N+  L+F+ G + GLG    + +++T+
Sbjct: 69  LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITV 128

Query: 128 TCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSL 187
              YF  RR LA  L S G S+G+ ++  L R L+E  G  G  L+ G + L+   CG++
Sbjct: 129 LGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAI 188

Query: 188 MRPLQSSDCPLPKKIAP 204
           +RP+ +S  P  K+  P
Sbjct: 189 IRPVATSVAPETKECPP 205



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 13/190 (6%)

Query: 294 CGETVA------LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLI 346
           CG T+       + ++     ++I  +++ + GFP P + +   A   +V E++  + LI
Sbjct: 219 CGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LI 277

Query: 347 SIIGIMTAVGKLLLGILADFKWI--NTLYLYVATLIIMGLA--LCAIPFAKSYVTLALLS 402
           SIIG      + L G++A       +  YL+   L++ GL   +CA      +V +    
Sbjct: 278 SIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAAS-GDFWVLVGYCL 336

Query: 403 GILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDI 462
                ++G  ++   V    V +++   A G+     GL   + PP+ G   D T  +  
Sbjct: 337 AYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSY 396

Query: 463 AFYFSGFCVL 472
            FY S F ++
Sbjct: 397 VFYMSSFFLI 406


>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
          Length = 471

 Score =  131 bits (329), Expect = 2e-30
 Identities = 67/196 (34%), Positives = 109/196 (55%), Gaps = 1/196 (0%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
           PDGGWGWV+   +F    L YG   ++G+ + +  + F      TAW+ +LA  V   AS
Sbjct: 33  PDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAAS 92

Query: 67  PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
           PV S   + +GARPV +  G + + G + S+FA ++  L+   G++ G G  L++   + 
Sbjct: 93  PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152

Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
              +YF  RR LA+GL  TG+     + A   ++L++ +G  G LL++GA+ L++  CG+
Sbjct: 153 TLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGA 212

Query: 187 LMRPL-QSSDCPLPKK 201
           L+ PL    D P P +
Sbjct: 213 LLLPLVLPGDPPAPPR 228



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 14/211 (6%)

Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
           ++LF  + FS   +   L   G F P + +   A    +      + ++++  +  A  +
Sbjct: 236 LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL-VVAVAAMGDAGAR 294

Query: 358 LLLGILADFKWINTLYLYVATLIIMGLALCAIPFA------KSYVTLALLSGIL-GFLTG 410
           L+ G LAD  W+    L      + GL L  +         +S+    L + +  G   G
Sbjct: 295 LVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAG 354

Query: 411 NWSIFPY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGF 469
           +++   + V    VG+  +  A G++M    LG  LGPP+ G+  D T  +  +F  SG 
Sbjct: 355 SYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS 414

Query: 470 CVLLGGFIL--LLAALPSWDTCNKQLPKPAP 498
            +L G FI   L  ALPS   C    P   P
Sbjct: 415 LILSGSFIYIGLPRALPS---CGPASPPATP 442


>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
          Length = 515

 Score =  116 bits (290), Expect = 6e-26
 Identities = 65/198 (32%), Positives = 98/198 (49%), Gaps = 5/198 (2%)

Query: 2   ELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKG-----KTAWVGS 56
           E  + P+GGWGW+++  +       +G   A GVL++  L+ FG         KTAWVGS
Sbjct: 60  EPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGS 119

Query: 57  LASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLG 116
           L+ G+     P+ S+    FG R   +    +   GLM SSF  +I  L+ +YGI+   G
Sbjct: 120 LSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACG 179

Query: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176
           C   Y  ++ I   YF  R GL  G+++ GSSV   +   L R+L++  GL   L ++  
Sbjct: 180 CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCI 239

Query: 177 LALNILACGSLMRPLQSS 194
               +   G   RPL +S
Sbjct: 240 FMFVLFLAGFTYRPLATS 257



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 58/184 (31%), Positives = 95/184 (51%), Gaps = 7/184 (3%)

Query: 299 ALFKNKVFSALFIAILLFDIGGFPPSL-LMEDV-ARSSNVKEEEFIMPLISIIGIMTAVG 356
           A+FK   ++   + I L   G F P + LM+ V  R  + K +E ++     IG+ + VG
Sbjct: 286 AIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVL---MCIGVTSGVG 342

Query: 357 KLLLGILADF-KWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW-SI 414
           +LL G +AD+   +  +YL V +   +GL    IP    +  L  +  I+G   G + SI
Sbjct: 343 RLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISI 402

Query: 415 FPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
              +  + VG + ++ A G L+ F  +  ++GPPI G   D   +YD+AFY +G   L+G
Sbjct: 403 MAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIG 462

Query: 475 GFIL 478
           G +L
Sbjct: 463 GAVL 466


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score =  101 bits (252), Expect = 1e-21
 Identities = 67/210 (31%), Positives = 101/210 (48%), Gaps = 6/210 (2%)

Query: 7   PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKT----AWVGSLASGVG 62
           P+GG+GWV+VF +       +G   +VG+LY   L+   E   +     AWVG+LA G+ 
Sbjct: 169 PEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMI 228

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAG-GLMLSSFAPNIYFLFFSYGIVVGLGCGLLY 121
              SP+ S+     G R +T  +G  VA  GL  SSF  ++   +F+YGI+ G GC   +
Sbjct: 229 FFCSPIVSIFTDRLGCR-ITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAF 287

Query: 122 TATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNI 181
             ++ I   YF  R GLA G++S GSS+    +  L RML +   L     ++      +
Sbjct: 288 QPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVL 347

Query: 182 LACGSLMRPLQSSDCPLPKKIAPEDLPDKY 211
           +      RPL  S    P K     L  ++
Sbjct: 348 MLLSLTYRPLLPSSQDTPSKRGVRTLHQRF 377



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 5/187 (2%)

Query: 300 LFKNKVFSALFIAILLFDIGGFPPSL-LMEDVARSSNVKEEEFIMPLISIIGIMTAVGKL 358
           +F+ + +      I    +G F P + LM+ V    +  +E ++  L+  IG  + +G+L
Sbjct: 389 VFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWV--LLVCIGATSGLGRL 446

Query: 359 LLGILAD-FKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW-SIFP 416
           + G ++D    +  +YL V + +++GL    IP  + +  L ++   LG   G + +I  
Sbjct: 447 VSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMA 506

Query: 417 YVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGF 476
            +  + VG  + + A G L+    L    GPPI G   +    Y +AFYF+G   ++G  
Sbjct: 507 PIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAV 566

Query: 477 ILLLAAL 483
           IL    L
Sbjct: 567 ILFFVPL 573


>gi|169217968 PREDICTED: similar to solute carrier family 16, member
           5 [Homo sapiens]
          Length = 453

 Score = 95.9 bits (237), Expect = 8e-20
 Identities = 50/144 (34%), Positives = 81/144 (56%)

Query: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120
           V L   P+CS+ V  FG R   +  G + + G++ SSF+ N+  L+F+ G + GLG    
Sbjct: 10  VALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 69

Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180
           + +++T+   YF  RR LA  L S G S+G+ ++  L R L+E  G  G  L+ G + L+
Sbjct: 70  FQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLH 129

Query: 181 ILACGSLMRPLQSSDCPLPKKIAP 204
              CG+++RP+ +S  P  K+  P
Sbjct: 130 CCICGAIIRPVATSVAPETKECPP 153



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 13/190 (6%)

Query: 294 CGETVA------LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLI 346
           CG T+       + ++     ++I  +++ + GFP P + +   A   +V E++  + LI
Sbjct: 167 CGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LI 225

Query: 347 SIIGIMTAVGKLLLGILADFKWI--NTLYLYVATLIIMGLA--LCAIPFAKSYVTLALLS 402
           SIIG      + L G++A       +  YL+   L++ GL   +CA      +V +    
Sbjct: 226 SIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAAS-GDFWVLVGYCL 284

Query: 403 GILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDI 462
                ++G  ++   V    V +++   A G+     GL   + PP+ G   D T  +  
Sbjct: 285 AYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSY 344

Query: 463 AFYFSGFCVL 472
            FY S F ++
Sbjct: 345 VFYMSSFFLI 354


>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 3/121 (2%)

Query: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAG-GLMLSSFAPNIYFLFFSYGIV-VGLGCG 118
           V L+ +P   L  +  G  P+ IF+GF +     ++ +F+ +  FL  +  +  +G  C 
Sbjct: 141 VQLITNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCS 199

Query: 119 LLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALA 178
            +    +  +    D+ RG  +G+   G ++G+ +      +L EF G     L++ AL 
Sbjct: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALV 259

Query: 179 L 179
           L
Sbjct: 260 L 260


>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
          Length = 456

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 18/141 (12%)

Query: 356 GKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415
           G  L+ I A F ++  +++     I+ G+ L  +P    ++ +  L  ++  ++      
Sbjct: 91  GNYLVHIGAKFMFVAGMFVSGGVTILFGV-LDRVPDGPVFIAMCFLVRVMDAVS------ 143

Query: 416 PYVTTKTVGIEKLAHAY--------GILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFS 467
            +    T     LA A+        G L  F+GLG  LGPP+ G+ Y  +  Y++ F   
Sbjct: 144 -FAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFLYQ-SFGYEVPFIVL 201

Query: 468 GFCVLLGGFILLLAALPSWDT 488
           G CV+L    L +  LP++++
Sbjct: 202 G-CVVLLMVPLNMYILPNYES 221


>gi|215272392 solute carrier family 18 (vesicular monoamine), member
           1 isoform c [Homo sapiens]
          Length = 472

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122
           LL +P      +  G   + +F+GF++     +       Y L F    + G+G      
Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209

Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179
           A + +    + D   RG A+G    G ++GL + A    ++ EF G     LI+  LAL
Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268


>gi|215272390 solute carrier family 18 (vesicular monoamine), member
           1 isoform b [Homo sapiens]
          Length = 493

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122
           LL +P      +  G   + +F+GF++     +       Y L F    + G+G      
Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209

Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179
           A + +    + D   RG A+G    G ++GL + A    ++ EF G     LI+  LAL
Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268


>gi|208879454 solute carrier family 18 (vesicular monoamine), member
           1 isoform a [Homo sapiens]
          Length = 525

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122
           LL +P      +  G   + +F+GF++     +       Y L F    + G+G      
Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209

Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179
           A + +    + D   RG A+G    G ++GL + A    ++ EF G     LI+  LAL
Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268


>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
           isoform a [Homo sapiens]
          Length = 525

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122
           LL +P      +  G   + +F+GF++     +       Y L F    + G+G      
Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209

Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179
           A + +    + D   RG A+G    G ++GL + A    ++ EF G     LI+  LAL
Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268


>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
          Length = 736

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 9/158 (5%)

Query: 345 LISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGI 404
           ++  +G+ +A+G ++ GI+   +   + +     L+I+G+ L        + T    S  
Sbjct: 504 MLLAMGLSSAIG-IMQGIITPLQDTFSFFRKHTKLLIVGVFLLMF-VCGLFFTRPSGSYF 561

Query: 405 LGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLG---PPIVGWFYDWTQTYD 461
           +  L+  W +FP +         ++ AYG   F A L   LG    PI GW   W     
Sbjct: 562 IRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGWL--WPHLCP 619

Query: 462 IAFYFSGFCVLLGGFILLLAALPSWD-TCNKQLPKPAP 498
           +      F  ++    +      SWD + +K++ +P P
Sbjct: 620 VVLLII-FVTMMVHLCMKPITYMSWDSSTSKEVLRPYP 656


>gi|32483369 origin recognition complex, subunit 3 isoform 1 [Homo
           sapiens]
          Length = 712

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 58/260 (22%), Positives = 102/260 (39%), Gaps = 47/260 (18%)

Query: 182 LACGSLMRPLQSSDCPLPKKIAPEDLPD-KYSIYNEKGKNLEENINILDKSYSSEEKCRI 240
           L  GSL   LQ++  P    +  +D PD K+ +     + ++  ++I  K    EE   +
Sbjct: 116 LTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKE---EESVHV 172

Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300
           T     +  DSL     TVT   +P+   K         K+    +WQ            
Sbjct: 173 TQRKTHYSMDSLSSWYMTVTQKTDPKMLSK---------KRTTSSQWQ------------ 211

Query: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTA---VGK 357
                  +  + ++L D+  F   +L + +  SS    E    PLI I GI T+   + +
Sbjct: 212 -------SPPVVVILKDMESFATKVLQDFIIISSQHLHE---FPLILIFGIATSPIIIHR 261

Query: 358 LLLGILADFKWINTLYL-----YVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW 412
           LL   ++    I          ++ T++   L     PF  +   L +L+ I  FL  ++
Sbjct: 262 LLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNI--FLYHDF 319

Query: 413 SIFPYVTTKTVGIEKLAHAY 432
           S+  ++  K + +  L H Y
Sbjct: 320 SVQNFI--KGLQLSLLEHFY 337


>gi|32483367 origin recognition complex, subunit 3 isoform 2 [Homo
           sapiens]
          Length = 711

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 58/260 (22%), Positives = 102/260 (39%), Gaps = 47/260 (18%)

Query: 182 LACGSLMRPLQSSDCPLPKKIAPEDLPD-KYSIYNEKGKNLEENINILDKSYSSEEKCRI 240
           L  GSL   LQ++  P    +  +D PD K+ +     + ++  ++I  K    EE   +
Sbjct: 116 LTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKE---EESVHV 172

Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300
           T     +  DSL     TVT   +P+   K         K+    +WQ            
Sbjct: 173 TQRKTHYSMDSLSSWYMTVTQKTDPKMLSK---------KRTTSSQWQ------------ 211

Query: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTA---VGK 357
                  +  + ++L D+  F   +L + +  SS    E    PLI I GI T+   + +
Sbjct: 212 -------SPPVVVILKDMESFATKVLQDFIIISSQHLHE---FPLILIFGIATSPIIIHR 261

Query: 358 LLLGILADFKWINTLYL-----YVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW 412
           LL   ++    I          ++ T++   L     PF  +   L +L+ I  FL  ++
Sbjct: 262 LLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNI--FLYHDF 319

Query: 413 SIFPYVTTKTVGIEKLAHAY 432
           S+  ++  K + +  L H Y
Sbjct: 320 SVQNFI--KGLQLSLLEHFY 337


>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
          Length = 490

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 32/144 (22%), Positives = 61/144 (42%), Gaps = 8/144 (5%)

Query: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120
           +  L++P+       +G +   + + F     + L   +P  YF   S   V  +   ++
Sbjct: 84  LSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVV 143

Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180
           +     IT ++    R +A GL+S   +  L    A+   L   YG    L++V A A+ 
Sbjct: 144 FAYVADITQEH---ERSMAYGLVSATFAASLVTSPAIGAYLGRVYG--DSLVVVLATAIA 198

Query: 181 ILACGSLMRPLQSSDCPLPKKIAP 204
           +L    ++  +  S   LP+K+ P
Sbjct: 199 LLDICFILVAVPES---LPEKMRP 219


>gi|166064062 tumor suppressing subtransferable candidate 5 [Homo
           sapiens]
          Length = 424

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 39/122 (31%), Positives = 50/122 (40%), Gaps = 10/122 (8%)

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLML------SSFAPNIYFLFFSYGIVVGLG 116
           LL  PV        GAR     S F+ A  L L      S   P +Y LF S   + G  
Sbjct: 73  LLGGPVFGRFADQRGARAALTLS-FLAALALYLLLAAASSPALPGVYLLFASR--LPGAL 129

Query: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176
              L  A + IT     + R  ALG +     VG+ + + L   LV  YG+  C  I+ A
Sbjct: 130 MHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQ-CPAILAA 188

Query: 177 LA 178
           LA
Sbjct: 189 LA 190



 Score = 29.3 bits (64), Expect = 8.9
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 396 VTLALLSGILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYD 455
           +T  L +  L  L   +SI PY++ K +G++ +A  +G L    G+   LG P+ G F D
Sbjct: 28  LTYVLAATELTCLFMQFSIVPYLSRK-LGLDSIA--FGYLQTTFGVLQLLGGPVFGRFAD 84

Query: 456 WTQTYDIAFYFSGFCVLLGGFILLLAA 482
             Q    A     F   L  ++LL AA
Sbjct: 85  --QRGARAALTLSFLAALALYLLLAAA 109


>gi|166064060 tumor suppressing subtransferable candidate 5 [Homo
           sapiens]
          Length = 424

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 39/122 (31%), Positives = 50/122 (40%), Gaps = 10/122 (8%)

Query: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLML------SSFAPNIYFLFFSYGIVVGLG 116
           LL  PV        GAR     S F+ A  L L      S   P +Y LF S   + G  
Sbjct: 73  LLGGPVFGRFADQRGARAALTLS-FLAALALYLLLAAASSPALPGVYLLFASR--LPGAL 129

Query: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176
              L  A + IT     + R  ALG +     VG+ + + L   LV  YG+  C  I+ A
Sbjct: 130 MHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQ-CPAILAA 188

Query: 177 LA 178
           LA
Sbjct: 189 LA 190



 Score = 29.3 bits (64), Expect = 8.9
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 396 VTLALLSGILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYD 455
           +T  L +  L  L   +SI PY++ K +G++ +A  +G L    G+   LG P+ G F D
Sbjct: 28  LTYVLAATELTCLFMQFSIVPYLSRK-LGLDSIA--FGYLQTTFGVLQLLGGPVFGRFAD 84

Query: 456 WTQTYDIAFYFSGFCVLLGGFILLLAA 482
             Q    A     F   L  ++LL AA
Sbjct: 85  --QRGARAALTLSFLAALALYLLLAAA 109


>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
            sapiens]
          Length = 1791

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 20/155 (12%)

Query: 204  PEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGDWKQD--SLLHK------ 255
            PE     Y ++ E  K   + +  ++    SE++  +T+ +   K D  S+L +      
Sbjct: 940  PEPEQQAYELHQENKKPTSQRVQSVEIDMFSEDEPHLTIQDPRKKSDVTSILSECSTIDL 999

Query: 256  ------NPTVTHTKEPETYKKKVAEQTYFCKQLAKRK--WQLYKNYCGETVALFKNKVFS 307
                   P +   K+PE    K     + C  + KRK  W ++ N       + K+  F 
Sbjct: 1000 QDGFGWLPEMVPKKQPERCLPKGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSWFE 1059

Query: 308  ALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFI 342
            +  I ++L   G    +L+ EDV   +  K +E +
Sbjct: 1060 SFIIFVILLSSG----ALIFEDVHLENQPKIQELL 1090


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.142    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,516,169
Number of Sequences: 37866
Number of extensions: 864565
Number of successful extensions: 2599
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2522
Number of HSP's gapped (non-prelim): 78
length of query: 509
length of database: 18,247,518
effective HSP length: 107
effective length of query: 402
effective length of database: 14,195,856
effective search space: 5706734112
effective search space used: 5706734112
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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