BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|34916028 solute carrier family 16 (monocarboxylic acid transporters), member 9 [Homo sapiens] (509 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 1033 0.0 gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 277 1e-74 gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 190 2e-48 gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 176 6e-44 gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 173 4e-43 gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 150 2e-36 gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 147 2e-35 gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 144 2e-34 gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 143 4e-34 gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 143 4e-34 gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 143 4e-34 gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 135 1e-31 gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 132 6e-31 gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 131 2e-30 gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 116 6e-26 gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 101 1e-21 gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 96 8e-20 gi|42476325 solute carrier family 18 (vesicular monoamine), memb... 40 0.004 gi|16445357 hypothetical protein LOC116843 [Homo sapiens] 38 0.019 gi|215272392 solute carrier family 18 (vesicular monoamine), mem... 37 0.056 gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 37 0.056 gi|208879454 solute carrier family 18 (vesicular monoamine), mem... 37 0.056 gi|4506987 solute carrier family 18 (vesicular monoamine), membe... 37 0.056 gi|55749589 solute carrier family 6, member 16 [Homo sapiens] 35 0.12 gi|32483369 origin recognition complex, subunit 3 isoform 1 [Hom... 35 0.16 gi|32483367 origin recognition complex, subunit 3 isoform 2 [Hom... 35 0.16 gi|39753965 hippocampus abundant transcript 1 [Homo sapiens] 35 0.16 gi|166064062 tumor suppressing subtransferable candidate 5 [Homo... 35 0.21 gi|166064060 tumor suppressing subtransferable candidate 5 [Homo... 35 0.21 gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo... 34 0.28 >gi|34916028 solute carrier family 16 (monocarboxylic acid transporters), member 9 [Homo sapiens] Length = 509 Score = 1033 bits (2671), Expect = 0.0 Identities = 509/509 (100%), Positives = 509/509 (100%) Query: 1 MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG 60 MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG Sbjct: 1 MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG 60 Query: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL Sbjct: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120 Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN Sbjct: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180 Query: 181 ILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRI 240 ILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRI Sbjct: 181 ILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRI 240 Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL Sbjct: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300 Query: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLL 360 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLL Sbjct: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLL 360 Query: 361 GILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTT 420 GILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTT Sbjct: 361 GILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTT 420 Query: 421 KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480 KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL Sbjct: 421 KTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480 Query: 481 AALPSWDTCNKQLPKPAPTTFLYKVASNV 509 AALPSWDTCNKQLPKPAPTTFLYKVASNV Sbjct: 481 AALPSWDTCNKQLPKPAPTTFLYKVASNV 509 >gi|41327156 solute carrier family 16 (monocarboxylic acid transporters), member 14 [Homo sapiens] Length = 510 Score = 277 bits (709), Expect = 1e-74 Identities = 164/482 (34%), Positives = 256/482 (53%), Gaps = 17/482 (3%) Query: 3 LKKSP--DGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASG 60 LK P DGGW W++V SF L GS +A+GVL +EWL+ F + +G TAWV SL+ G Sbjct: 22 LKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMG 81 Query: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120 + L+ P L +++ G R I G + + G +LS++A N+++LF ++G+ GLG G+ Sbjct: 82 ITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMA 141 Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180 Y V + +YF RR LA GL +TG+ G F+ L + L YG +LI GA++LN Sbjct: 142 YLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLN 201 Query: 181 ILACGSLMRPLQSSDCPL-PKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCR 239 + CG+LMRPL P P + LP + E++ + +EEK Sbjct: 202 LCVCGALMRPLSPGKNPNDPGEKDVRGLP----------AHSTESVKSTGQQGRTEEKDG 251 Query: 240 ITLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVA 299 L N + D + P ++ + + ++ ++ K Y Y G T + Sbjct: 252 -GLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFG-TAS 309 Query: 300 LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKL 358 LF N++F A FI LF F P + + ++ N+ E+ + PL SII I+ GK+ Sbjct: 310 LFTNRMFVA-FIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKV 368 Query: 359 LLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYV 418 +LG++AD I+ +++ + L++ +P +Y LA++ ++GF +G +S+ P V Sbjct: 369 ILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVV 428 Query: 419 TTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFIL 478 T VGIE LA+AYGI++ G+ LGPP GW YD TQ YD +FY G ++G L Sbjct: 429 TEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFL 488 Query: 479 LL 480 L+ Sbjct: 489 LI 490 >gi|4759114 solute carrier family 16, member 4 [Homo sapiens] Length = 487 Score = 190 bits (483), Expect = 2e-48 Identities = 129/487 (26%), Positives = 223/487 (45%), Gaps = 49/487 (10%) Query: 5 KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64 K+ DGGWGW+IV FL G + ++ + + F + W+GS+ S + Sbjct: 13 KTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFC 72 Query: 65 ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124 A P+ ++ G + +I F+V GG ++SS+A +I FL + G++ GLG LY Sbjct: 73 AGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVA 132 Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184 +T +YF R L+ + +G + F+ A + L++ Y G L++ GA+ALN++ Sbjct: 133 AVVTTKYFKKRLALSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIALNLVPS 191 Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKC----RI 240 L+RP+ + S +KG +L + +++++E C Sbjct: 192 SMLLRPIHIKS-------------ENNSGIKDKGSSLSAH---GPEAHATETHCHETEES 235 Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYK--------KKVAEQ-----TYFCKQLAKRKW 287 T+ + ++ L KN TV+ + E Y K E+ ++ CKQL Sbjct: 236 TIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLF---- 291 Query: 288 QLYKNYCGETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLIS 347 ++LF+N F + LL + F P+ + A++ + + L+S Sbjct: 292 ---------DISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMD-ASYLVS 341 Query: 348 IIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGF 407 + GI+ V +++ G +AD WI + + + LI+ G+ P A ++ L + Sbjct: 342 VAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAI 401 Query: 408 LTGNW-SIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYF 466 G + ++ V + G+ FFAG+ GPPI GW YD+TQTY+ +FYF Sbjct: 402 FAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYF 461 Query: 467 SGFCVLL 473 SG C LL Sbjct: 462 SGICYLL 468 >gi|157041233 solute carrier family 16 (monocarboxylic acid transporters), member 12 [Homo sapiens] Length = 486 Score = 176 bits (445), Expect = 6e-44 Identities = 131/481 (27%), Positives = 220/481 (45%), Gaps = 65/481 (13%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGW+IV FL + + ++E+ F + +TAW+ S+ V +L + Sbjct: 13 PDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCA 72 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 P+ S+ + + + G + + GL+LSSFA ++ L+ + G++ GLG L Y+ + Sbjct: 73 PLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIA 132 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 + +YF R+ LA G+ +GS +G FI A + ++L+E + G LLI+G LN+ CG+ Sbjct: 133 MVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGA 192 Query: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246 LMRP+ L+E+ ++++ CR Sbjct: 193 LMRPI----------------------------TLKEDHTTPEQNH----VCRT------ 214 Query: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306 +++ + +P + TKE QT C L + Y ++ F Sbjct: 215 -QKEDIKRVSPYSSLTKE--------WAQTCLC-------CCLQQEYSFLLMSDFVVLAV 258 Query: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366 S LF+A G P + + A S V ++ L+SI+G++ +G + G L D Sbjct: 259 SVLFMA-----YGCSPLFVYLVPYALSVGVSHQQAAF-LMSILGVIDIIGNITFGWLTDR 312 Query: 367 KWINTLYLYVATLIIMGL-ALC--AIPFAKSYVTLALLSGILGFLTGNW-SIFPYVTTKT 422 + + Y YV L +G+ LC +P +S L S G+ G + ++ P VTT+ Sbjct: 313 RCLKN-YQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEI 371 Query: 423 VGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAA 482 VG L+ A G++ F + + PPI G D T +Y AF GF ++ +L A Sbjct: 372 VGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFAR 431 Query: 483 L 483 L Sbjct: 432 L 432 >gi|40789261 solute carrier family 16, member 6 [Homo sapiens] Length = 523 Score = 173 bits (438), Expect = 4e-43 Identities = 128/479 (26%), Positives = 222/479 (46%), Gaps = 32/479 (6%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGW + F + YG GV + + +D+F E + +W+ S+ V ++ Sbjct: 19 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSA 78 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 P+ ++ + FG R V + G +V+ G++ +SF+ + ++ + GI+ GLG + TVT Sbjct: 79 PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 I QYF RR + + STG +F +A L E G LL VG L LNI+ G+ Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198 Query: 187 LMRPLQSSDCPLPKKIAPEDLPD-KYSIYNEKGKNLEENINILDKSYSSEEKCRITLANG 245 L+RP+ PK + E+ + +Y + NEK + ++I+ + +S + Sbjct: 199 LLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNV------- 251 Query: 246 DWKQDSLLHKNPTVTHTK-EPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNK 304 PT T+ + EP+ ++V +T + +++K L ++ K K Sbjct: 252 -----------PTHTNLELEPKADMQQVLVKT--SPRPSEKKAPLL------DFSILKEK 292 Query: 305 VFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILA 364 F + L +G F PSL + + S + ++ L+S + I G++ G + Sbjct: 293 SFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAF-LLSTMAIAEVFGRIGAGFVL 351 Query: 365 DFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLT---GNWSIFPYVTTK 421 + + I +Y+ + +I++ ++L A FA + L S GF+ G I Sbjct: 352 NREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDD 411 Query: 422 TVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480 VGIEK++ A G+ +F + GPP+ G D ++ Y AFY + L L L Sbjct: 412 VVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLAL 470 >gi|115583685 solute carrier family 16, member 1 [Homo sapiens] Length = 500 Score = 150 bits (380), Expect = 2e-36 Identities = 125/478 (26%), Positives = 204/478 (42%), Gaps = 56/478 (11%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGW +V +F++ Y P ++ V + E F + +W+ S+ V Sbjct: 14 PDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGG 73 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 P+ S+ V+ +G+R V I G + GL+ +SF + L+ G++ GLG +T Sbjct: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 + +YF RR LA GL GS V L A L ++ +G G LI+G L LN G+ Sbjct: 134 MIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGA 193 Query: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246 LMRP+ P P K GK DKS +S EK Sbjct: 194 LMRPIG----PKPTK---------------AGK---------DKSKASLEKA----GKSG 221 Query: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306 K+D LH T + P+ K+ V +Q + T LF ++ F Sbjct: 222 VKKD--LHDANTDLIGRHPKQEKRSV--------------FQTINQFLDLT--LFTHRGF 263 Query: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366 ++ G F P + + +S + E+ L+SI+ + V + +G++A+ Sbjct: 264 LLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF-LLSILAFVDMVARPSMGLVANT 322 Query: 367 KWI--NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW--SIFPYVTTKT 422 K I Y + A+++ G+ P + +YV + +G GF G W S+ Sbjct: 323 KPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFG-WLSSVLFETLMDL 381 Query: 423 VGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480 VG ++ + A G++ LGPP++G D Y ++ G +++ G L + Sbjct: 382 VGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFI 439 >gi|24431958 solute carrier family 16, member 7 [Homo sapiens] Length = 478 Score = 147 bits (372), Expect = 2e-35 Identities = 120/477 (25%), Positives = 195/477 (40%), Gaps = 70/477 (14%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGW++V +F++ Y P AV V + E F + AW+ S+ V Sbjct: 14 PDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGG 73 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 PV S+ V+ +G+RPV I G + G++L+SF+ ++ L+ + G + GLG +T Sbjct: 74 PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 I +YF +R +A GL GS V L A + L +G G LI+G+L LN GS Sbjct: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193 Query: 187 LMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGD 246 LM + + P K N+ GK +++ Sbjct: 194 LM-----------RPLGPNQTTSKSK--NKTGKTEDDS---------------------- 218 Query: 247 WKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVF 306 P+ K K K W+ Y +LFK++ F Sbjct: 219 -----------------SPKKIKTK------------KSTWEKVNKYLD--FSLFKHRGF 247 Query: 307 SALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADF 366 ++ +G F P + + A+ + E L+S++ + + +G++A+ Sbjct: 248 LIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAF-LLSVMAFVDMFARPSVGLIANS 306 Query: 367 KWINTLYLYVATLIIMGLALCAI--PFAKSYVTLALLSGILGFLTGNWSIFPYVT-TKTV 423 K+I Y + IM +C + P A+ Y +L L + G G+ S + T V Sbjct: 307 KYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLV 366 Query: 424 GIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLL 480 G + + A G++ LGPP+ G D T Y + G V+ LL+ Sbjct: 367 GAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI 423 >gi|42475555 monocarboxylate transporter 13 [Homo sapiens] Length = 426 Score = 144 bits (362), Expect = 2e-34 Identities = 72/191 (37%), Positives = 110/191 (57%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGWV+V +F L +G + GV ++E++ AF E + +W+ S+ V S Sbjct: 8 PDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGS 67 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 PV S + FG RPV + G + A G++L+SFA ++ L+ S G++ G G L + T+ Sbjct: 68 PVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLA 127 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 YF RR LA GL TG + F +A + L+ Y G LL+V AL+L+++ACG+ Sbjct: 128 CLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGA 187 Query: 187 LMRPLQSSDCP 197 L+RP ++ P Sbjct: 188 LLRPPSLAEDP 198 Score = 60.5 bits (145), Expect = 4e-09 Identities = 48/186 (25%), Positives = 85/186 (45%), Gaps = 4/186 (2%) Query: 296 ETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMP-LISIIGIMTA 354 + +L + F +A+ L + G F P L + VA ++ + L+S++ I Sbjct: 206 QLTSLLHHGPFLRYTVALTLINTGYFIPYLHL--VAHLQDLDWDPLPAAFLLSVVAISDL 263 Query: 355 VGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSI 414 VG+++ G L D L + + G++L P A++ L L+ GF +G + Sbjct: 264 VGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAP 323 Query: 415 FPY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLL 473 + V + +G ++ G+L +G LGPP+ G+ D T Y +F +G +L Sbjct: 324 LAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLS 383 Query: 474 GGFILL 479 G ILL Sbjct: 384 GSGILL 389 >gi|109288010 solute carrier family 16, member 3 [Homo sapiens] Length = 465 Score = 143 bits (360), Expect = 4e-34 Identities = 75/214 (35%), Positives = 116/214 (54%) Query: 5 KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64 K+PDGGWGW ++F F+ Y P AV V + E + FG G TAW+ S+ + Sbjct: 14 KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73 Query: 65 ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124 P+CS+CV+ FG RPV + G + G++ +SF +I ++ + G++ GLG L + + Sbjct: 74 TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133 Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184 + + +YF RR +A GL + GS V L + L ++L + YG G LI+G L LN C Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193 Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218 +LMRPL + P P S++ ++G Sbjct: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227 Score = 53.1 bits (126), Expect = 6e-07 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%) Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357 +++F+++ F +A + +G F P + + A+ V + + L++I+G + + Sbjct: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278 Query: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415 G +A + ++YL+ ++ GLA A A Y L + G G Sbjct: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338 Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474 + V VG K + A G+++ + +GPP G D T Y F +G VL Sbjct: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398 Query: 475 GFILLLAALPSWDTCNKQLPK-PAP 498 ILLL C ++ PK P P Sbjct: 399 SLILLLGNF----FCIRKKPKEPQP 419 >gi|109288012 solute carrier family 16, member 3 [Homo sapiens] Length = 465 Score = 143 bits (360), Expect = 4e-34 Identities = 75/214 (35%), Positives = 116/214 (54%) Query: 5 KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64 K+PDGGWGW ++F F+ Y P AV V + E + FG G TAW+ S+ + Sbjct: 14 KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73 Query: 65 ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124 P+CS+CV+ FG RPV + G + G++ +SF +I ++ + G++ GLG L + + Sbjct: 74 TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133 Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184 + + +YF RR +A GL + GS V L + L ++L + YG G LI+G L LN C Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193 Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218 +LMRPL + P P S++ ++G Sbjct: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227 Score = 53.1 bits (126), Expect = 6e-07 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%) Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357 +++F+++ F +A + +G F P + + A+ V + + L++I+G + + Sbjct: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278 Query: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415 G +A + ++YL+ ++ GLA A A Y L + G G Sbjct: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338 Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474 + V VG K + A G+++ + +GPP G D T Y F +G VL Sbjct: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398 Query: 475 GFILLLAALPSWDTCNKQLPK-PAP 498 ILLL C ++ PK P P Sbjct: 399 SLILLLGNF----FCIRKKPKEPQP 419 >gi|4759112 solute carrier family 16, member 3 [Homo sapiens] Length = 465 Score = 143 bits (360), Expect = 4e-34 Identities = 75/214 (35%), Positives = 116/214 (54%) Query: 5 KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLL 64 K+PDGGWGW ++F F+ Y P AV V + E + FG G TAW+ S+ + Sbjct: 14 KAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYG 73 Query: 65 ASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTAT 124 P+CS+CV+ FG RPV + G + G++ +SF +I ++ + G++ GLG L + + Sbjct: 74 TGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPS 133 Query: 125 VTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILAC 184 + + +YF RR +A GL + GS V L + L ++L + YG G LI+G L LN C Sbjct: 134 LIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVC 193 Query: 185 GSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKG 218 +LMRPL + P P S++ ++G Sbjct: 194 AALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRG 227 Score = 53.1 bits (126), Expect = 6e-07 Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 9/205 (4%) Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357 +++F+++ F +A + +G F P + + A+ V + + L++I+G + + Sbjct: 220 LSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAF-LLTILGFIDIFAR 278 Query: 358 LLLGILADFKWIN--TLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415 G +A + ++YL+ ++ GLA A A Y L + G G Sbjct: 279 PAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGAL 338 Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474 + V VG K + A G+++ + +GPP G D T Y F +G VL Sbjct: 339 QFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTS 398 Query: 475 GFILLLAALPSWDTCNKQLPK-PAP 498 ILLL C ++ PK P P Sbjct: 399 SLILLLGNF----FCIRKKPKEPQP 419 >gi|114796626 solute carrier family 16, member 8 [Homo sapiens] Length = 504 Score = 135 bits (339), Expect = 1e-31 Identities = 70/184 (38%), Positives = 105/184 (57%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGWV++ F+ YG P AV V + + F G TAWV S+ + Sbjct: 13 PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTG 72 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 PV S+ V+ FG RPV + G + + G++L+SFA + L+ + G++ GLG L + ++ Sbjct: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 + YF+ RR LA GL + GS V L + L + L+E +G G L++G L L+ ACG+ Sbjct: 133 MLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGA 192 Query: 187 LMRP 190 +MRP Sbjct: 193 VMRP 196 Score = 64.3 bits (155), Expect = 2e-10 Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 9/205 (4%) Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357 +A+ ++ F+ + L +G F P++L+ + A+ + V + + L+SI+G + V + Sbjct: 245 LAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAF-LLSIVGFVDIVAR 303 Query: 358 LLLGILADFKWI--NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415 G LA + + YL+ L+ GL + A+SY L G G Sbjct: 304 PACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGAL 363 Query: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474 + V VG + A G+++ +GPP G D + Y+I FY +G V L Sbjct: 364 QFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALA 423 Query: 475 GFILLLAALPSWDTCNKQLPKPAPT 499 G + +A C + K AP+ Sbjct: 424 GVFMAVAT-----NCCLRCAKAAPS 443 >gi|4759116 solute carrier family 16, member 5 [Homo sapiens] Length = 505 Score = 132 bits (333), Expect = 6e-31 Identities = 66/197 (33%), Positives = 109/197 (55%) Query: 8 DGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASP 67 DG W WV++ + +TQ L G P +G+ + E F +T+W S+ + V +A P Sbjct: 9 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGP 68 Query: 68 VCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTI 127 +CS+ V FG R + G + + G++ SSF+ N+ L+F+ G + GLG + +++T+ Sbjct: 69 LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITV 128 Query: 128 TCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSL 187 YF RR LA L S G S+G+ ++ L R L+E G G L+ G + L+ CG++ Sbjct: 129 LGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAI 188 Query: 188 MRPLQSSDCPLPKKIAP 204 +RP+ +S P K+ P Sbjct: 189 IRPVATSVAPETKECPP 205 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 13/190 (6%) Query: 294 CGETVA------LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLI 346 CG T+ + ++ ++I +++ + GFP P + + A +V E++ + LI Sbjct: 219 CGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LI 277 Query: 347 SIIGIMTAVGKLLLGILADFKWI--NTLYLYVATLIIMGLA--LCAIPFAKSYVTLALLS 402 SIIG + L G++A + YL+ L++ GL +CA +V + Sbjct: 278 SIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAAS-GDFWVLVGYCL 336 Query: 403 GILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDI 462 ++G ++ V V +++ A G+ GL + PP+ G D T + Sbjct: 337 AYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSY 396 Query: 463 AFYFSGFCVL 472 FY S F ++ Sbjct: 397 VFYMSSFFLI 406 >gi|23503293 solute carrier family 16, member 11 [Homo sapiens] Length = 471 Score = 131 bits (329), Expect = 2e-30 Identities = 67/196 (34%), Positives = 109/196 (55%), Gaps = 1/196 (0%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66 PDGGWGWV+ +F L YG ++G+ + + + F TAW+ +LA V AS Sbjct: 33 PDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAAS 92 Query: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126 PV S + +GARPV + G + + G + S+FA ++ L+ G++ G G L++ + Sbjct: 93 PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152 Query: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186 +YF RR LA+GL TG+ + A ++L++ +G G LL++GA+ L++ CG+ Sbjct: 153 TLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGA 212 Query: 187 LMRPL-QSSDCPLPKK 201 L+ PL D P P + Sbjct: 213 LLLPLVLPGDPPAPPR 228 Score = 54.3 bits (129), Expect = 3e-07 Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 14/211 (6%) Query: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357 ++LF + FS + L G F P + + A + + ++++ + A + Sbjct: 236 LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAAL-VVAVAAMGDAGAR 294 Query: 358 LLLGILADFKWINTLYLYVATLIIMGLALCAIPFA------KSYVTLALLSGIL-GFLTG 410 L+ G LAD W+ L + GL L + +S+ L + + G G Sbjct: 295 LVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAG 354 Query: 411 NWSIFPY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGF 469 +++ + V VG+ + A G++M LG LGPP+ G+ D T + +F SG Sbjct: 355 SYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS 414 Query: 470 CVLLGGFIL--LLAALPSWDTCNKQLPKPAP 498 +L G FI L ALPS C P P Sbjct: 415 LILSGSFIYIGLPRALPS---CGPASPPATP 442 >gi|18699730 solute carrier family 16, member 10 [Homo sapiens] Length = 515 Score = 116 bits (290), Expect = 6e-26 Identities = 65/198 (32%), Positives = 98/198 (49%), Gaps = 5/198 (2%) Query: 2 ELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKG-----KTAWVGS 56 E + P+GGWGW+++ + +G A GVL++ L+ FG KTAWVGS Sbjct: 60 EPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGS 119 Query: 57 LASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLG 116 L+ G+ P+ S+ FG R + + GLM SSF +I L+ +YGI+ G Sbjct: 120 LSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACG 179 Query: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176 C Y ++ I YF R GL G+++ GSSV + L R+L++ GL L ++ Sbjct: 180 CSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCI 239 Query: 177 LALNILACGSLMRPLQSS 194 + G RPL +S Sbjct: 240 FMFVLFLAGFTYRPLATS 257 Score = 83.2 bits (204), Expect = 5e-16 Identities = 58/184 (31%), Positives = 95/184 (51%), Gaps = 7/184 (3%) Query: 299 ALFKNKVFSALFIAILLFDIGGFPPSL-LMEDV-ARSSNVKEEEFIMPLISIIGIMTAVG 356 A+FK ++ + I L G F P + LM+ V R + K +E ++ IG+ + VG Sbjct: 286 AIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVL---MCIGVTSGVG 342 Query: 357 KLLLGILADF-KWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW-SI 414 +LL G +AD+ + +YL V + +GL IP + L + I+G G + SI Sbjct: 343 RLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISI 402 Query: 415 FPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474 + + VG + ++ A G L+ F + ++GPPI G D +YD+AFY +G L+G Sbjct: 403 MAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIG 462 Query: 475 GFIL 478 G +L Sbjct: 463 GAVL 466 >gi|5730045 solute carrier family 16, member 2 [Homo sapiens] Length = 613 Score = 101 bits (252), Expect = 1e-21 Identities = 67/210 (31%), Positives = 101/210 (48%), Gaps = 6/210 (2%) Query: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKT----AWVGSLASGVG 62 P+GG+GWV+VF + +G +VG+LY L+ E + AWVG+LA G+ Sbjct: 169 PEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMI 228 Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAG-GLMLSSFAPNIYFLFFSYGIVVGLGCGLLY 121 SP+ S+ G R +T +G VA GL SSF ++ +F+YGI+ G GC + Sbjct: 229 FFCSPIVSIFTDRLGCR-ITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAF 287 Query: 122 TATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNI 181 ++ I YF R GLA G++S GSS+ + L RML + L ++ + Sbjct: 288 QPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVL 347 Query: 182 LACGSLMRPLQSSDCPLPKKIAPEDLPDKY 211 + RPL S P K L ++ Sbjct: 348 MLLSLTYRPLLPSSQDTPSKRGVRTLHQRF 377 Score = 65.1 bits (157), Expect = 1e-10 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 5/187 (2%) Query: 300 LFKNKVFSALFIAILLFDIGGFPPSL-LMEDVARSSNVKEEEFIMPLISIIGIMTAVGKL 358 +F+ + + I +G F P + LM+ V + +E ++ L+ IG + +G+L Sbjct: 389 VFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWV--LLVCIGATSGLGRL 446 Query: 359 LLGILAD-FKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW-SIFP 416 + G ++D + +YL V + +++GL IP + + L ++ LG G + +I Sbjct: 447 VSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMA 506 Query: 417 YVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGF 476 + + VG + + A G L+ L GPPI G + Y +AFYF+G ++G Sbjct: 507 PIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAV 566 Query: 477 ILLLAAL 483 IL L Sbjct: 567 ILFFVPL 573 >gi|169217968 PREDICTED: similar to solute carrier family 16, member 5 [Homo sapiens] Length = 453 Score = 95.9 bits (237), Expect = 8e-20 Identities = 50/144 (34%), Positives = 81/144 (56%) Query: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120 V L P+CS+ V FG R + G + + G++ SSF+ N+ L+F+ G + GLG Sbjct: 10 VALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 69 Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180 + +++T+ YF RR LA L S G S+G+ ++ L R L+E G G L+ G + L+ Sbjct: 70 FQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLH 129 Query: 181 ILACGSLMRPLQSSDCPLPKKIAP 204 CG+++RP+ +S P K+ P Sbjct: 130 CCICGAIIRPVATSVAPETKECPP 153 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 13/190 (6%) Query: 294 CGETVA------LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLI 346 CG T+ + ++ ++I +++ + GFP P + + A +V E++ + LI Sbjct: 167 CGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LI 225 Query: 347 SIIGIMTAVGKLLLGILADFKWI--NTLYLYVATLIIMGLA--LCAIPFAKSYVTLALLS 402 SIIG + L G++A + YL+ L++ GL +CA +V + Sbjct: 226 SIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAAS-GDFWVLVGYCL 284 Query: 403 GILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDI 462 ++G ++ V V +++ A G+ GL + PP+ G D T + Sbjct: 285 AYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSY 344 Query: 463 AFYFSGFCVL 472 FY S F ++ Sbjct: 345 VFYMSSFFLI 354 >gi|42476325 solute carrier family 18 (vesicular monoamine), member 2 [Homo sapiens] Length = 514 Score = 40.4 bits (93), Expect = 0.004 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 3/121 (2%) Query: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAG-GLMLSSFAPNIYFLFFSYGIV-VGLGCG 118 V L+ +P L + G P+ IF+GF + ++ +F+ + FL + + +G C Sbjct: 141 VQLITNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCS 199 Query: 119 LLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALA 178 + + + D+ RG +G+ G ++G+ + +L EF G L++ AL Sbjct: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALV 259 Query: 179 L 179 L Sbjct: 260 L 260 >gi|16445357 hypothetical protein LOC116843 [Homo sapiens] Length = 456 Score = 38.1 bits (87), Expect = 0.019 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 18/141 (12%) Query: 356 GKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415 G L+ I A F ++ +++ I+ G+ L +P ++ + L ++ ++ Sbjct: 91 GNYLVHIGAKFMFVAGMFVSGGVTILFGV-LDRVPDGPVFIAMCFLVRVMDAVS------ 143 Query: 416 PYVTTKTVGIEKLAHAY--------GILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFS 467 + T LA A+ G L F+GLG LGPP+ G+ Y + Y++ F Sbjct: 144 -FAAAMTASSSILAKAFPNNVATVLGSLETFSGLGLILGPPVGGFLYQ-SFGYEVPFIVL 201 Query: 468 GFCVLLGGFILLLAALPSWDT 488 G CV+L L + LP++++ Sbjct: 202 G-CVVLLMVPLNMYILPNYES 221 >gi|215272392 solute carrier family 18 (vesicular monoamine), member 1 isoform c [Homo sapiens] Length = 472 Score = 36.6 bits (83), Expect = 0.056 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122 LL +P + G + +F+GF++ + Y L F + G+G Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209 Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179 A + + + D RG A+G G ++GL + A ++ EF G LI+ LAL Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268 >gi|215272390 solute carrier family 18 (vesicular monoamine), member 1 isoform b [Homo sapiens] Length = 493 Score = 36.6 bits (83), Expect = 0.056 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122 LL +P + G + +F+GF++ + Y L F + G+G Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209 Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179 A + + + D RG A+G G ++GL + A ++ EF G LI+ LAL Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268 >gi|208879454 solute carrier family 18 (vesicular monoamine), member 1 isoform a [Homo sapiens] Length = 525 Score = 36.6 bits (83), Expect = 0.056 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122 LL +P + G + +F+GF++ + Y L F + G+G Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209 Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179 A + + + D RG A+G G ++GL + A ++ EF G LI+ LAL Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268 >gi|4506987 solute carrier family 18 (vesicular monoamine), member 1 isoform a [Homo sapiens] Length = 525 Score = 36.6 bits (83), Expect = 0.056 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%) Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122 LL +P + G + +F+GF++ + Y L F + G+G Sbjct: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209 Query: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179 A + + + D RG A+G G ++GL + A ++ EF G LI+ LAL Sbjct: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268 >gi|55749589 solute carrier family 6, member 16 [Homo sapiens] Length = 736 Score = 35.4 bits (80), Expect = 0.12 Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 9/158 (5%) Query: 345 LISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGI 404 ++ +G+ +A+G ++ GI+ + + + L+I+G+ L + T S Sbjct: 504 MLLAMGLSSAIG-IMQGIITPLQDTFSFFRKHTKLLIVGVFLLMF-VCGLFFTRPSGSYF 561 Query: 405 LGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLG---PPIVGWFYDWTQTYD 461 + L+ W +FP + ++ AYG F A L LG PI GW W Sbjct: 562 IRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGWL--WPHLCP 619 Query: 462 IAFYFSGFCVLLGGFILLLAALPSWD-TCNKQLPKPAP 498 + F ++ + SWD + +K++ +P P Sbjct: 620 VVLLII-FVTMMVHLCMKPITYMSWDSSTSKEVLRPYP 656 >gi|32483369 origin recognition complex, subunit 3 isoform 1 [Homo sapiens] Length = 712 Score = 35.0 bits (79), Expect = 0.16 Identities = 58/260 (22%), Positives = 102/260 (39%), Gaps = 47/260 (18%) Query: 182 LACGSLMRPLQSSDCPLPKKIAPEDLPD-KYSIYNEKGKNLEENINILDKSYSSEEKCRI 240 L GSL LQ++ P + +D PD K+ + + ++ ++I K EE + Sbjct: 116 LTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKE---EESVHV 172 Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300 T + DSL TVT +P+ K K+ +WQ Sbjct: 173 TQRKTHYSMDSLSSWYMTVTQKTDPKMLSK---------KRTTSSQWQ------------ 211 Query: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTA---VGK 357 + + ++L D+ F +L + + SS E PLI I GI T+ + + Sbjct: 212 -------SPPVVVILKDMESFATKVLQDFIIISSQHLHE---FPLILIFGIATSPIIIHR 261 Query: 358 LLLGILADFKWINTLYL-----YVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW 412 LL ++ I ++ T++ L PF + L +L+ I FL ++ Sbjct: 262 LLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNI--FLYHDF 319 Query: 413 SIFPYVTTKTVGIEKLAHAY 432 S+ ++ K + + L H Y Sbjct: 320 SVQNFI--KGLQLSLLEHFY 337 >gi|32483367 origin recognition complex, subunit 3 isoform 2 [Homo sapiens] Length = 711 Score = 35.0 bits (79), Expect = 0.16 Identities = 58/260 (22%), Positives = 102/260 (39%), Gaps = 47/260 (18%) Query: 182 LACGSLMRPLQSSDCPLPKKIAPEDLPD-KYSIYNEKGKNLEENINILDKSYSSEEKCRI 240 L GSL LQ++ P + +D PD K+ + + ++ ++I K EE + Sbjct: 116 LTFGSLTEALQNNVTPYVVSLQAKDCPDMKHFLQKLISQLMDCCVDIKSKE---EESVHV 172 Query: 241 TLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVAL 300 T + DSL TVT +P+ K K+ +WQ Sbjct: 173 TQRKTHYSMDSLSSWYMTVTQKTDPKMLSK---------KRTTSSQWQ------------ 211 Query: 301 FKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTA---VGK 357 + + ++L D+ F +L + + SS E PLI I GI T+ + + Sbjct: 212 -------SPPVVVILKDMESFATKVLQDFIIISSQHLHE---FPLILIFGIATSPIIIHR 261 Query: 358 LLLGILADFKWINTLYL-----YVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNW 412 LL ++ I ++ T++ L PF + L +L+ I FL ++ Sbjct: 262 LLPHAVSSLLCIELFQSLSCKEHLTTVLDKLLLTTQFPFKINEKVLQVLTNI--FLYHDF 319 Query: 413 SIFPYVTTKTVGIEKLAHAY 432 S+ ++ K + + L H Y Sbjct: 320 SVQNFI--KGLQLSLLEHFY 337 >gi|39753965 hippocampus abundant transcript 1 [Homo sapiens] Length = 490 Score = 35.0 bits (79), Expect = 0.16 Identities = 32/144 (22%), Positives = 61/144 (42%), Gaps = 8/144 (5%) Query: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120 + L++P+ +G + + + F + L +P YF S V + ++ Sbjct: 84 LSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVV 143 Query: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180 + IT ++ R +A GL+S + L A+ L YG L++V A A+ Sbjct: 144 FAYVADITQEH---ERSMAYGLVSATFAASLVTSPAIGAYLGRVYG--DSLVVVLATAIA 198 Query: 181 ILACGSLMRPLQSSDCPLPKKIAP 204 +L ++ + S LP+K+ P Sbjct: 199 LLDICFILVAVPES---LPEKMRP 219 >gi|166064062 tumor suppressing subtransferable candidate 5 [Homo sapiens] Length = 424 Score = 34.7 bits (78), Expect = 0.21 Identities = 39/122 (31%), Positives = 50/122 (40%), Gaps = 10/122 (8%) Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLML------SSFAPNIYFLFFSYGIVVGLG 116 LL PV GAR S F+ A L L S P +Y LF S + G Sbjct: 73 LLGGPVFGRFADQRGARAALTLS-FLAALALYLLLAAASSPALPGVYLLFASR--LPGAL 129 Query: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176 L A + IT + R ALG + VG+ + + L LV YG+ C I+ A Sbjct: 130 MHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQ-CPAILAA 188 Query: 177 LA 178 LA Sbjct: 189 LA 190 Score = 29.3 bits (64), Expect = 8.9 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Query: 396 VTLALLSGILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYD 455 +T L + L L +SI PY++ K +G++ +A +G L G+ LG P+ G F D Sbjct: 28 LTYVLAATELTCLFMQFSIVPYLSRK-LGLDSIA--FGYLQTTFGVLQLLGGPVFGRFAD 84 Query: 456 WTQTYDIAFYFSGFCVLLGGFILLLAA 482 Q A F L ++LL AA Sbjct: 85 --QRGARAALTLSFLAALALYLLLAAA 109 >gi|166064060 tumor suppressing subtransferable candidate 5 [Homo sapiens] Length = 424 Score = 34.7 bits (78), Expect = 0.21 Identities = 39/122 (31%), Positives = 50/122 (40%), Gaps = 10/122 (8%) Query: 63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLML------SSFAPNIYFLFFSYGIVVGLG 116 LL PV GAR S F+ A L L S P +Y LF S + G Sbjct: 73 LLGGPVFGRFADQRGARAALTLS-FLAALALYLLLAAASSPALPGVYLLFASR--LPGAL 129 Query: 117 CGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGA 176 L A + IT + R ALG + VG+ + + L LV YG+ C I+ A Sbjct: 130 MHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQ-CPAILAA 188 Query: 177 LA 178 LA Sbjct: 189 LA 190 Score = 29.3 bits (64), Expect = 8.9 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Query: 396 VTLALLSGILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYD 455 +T L + L L +SI PY++ K +G++ +A +G L G+ LG P+ G F D Sbjct: 28 LTYVLAATELTCLFMQFSIVPYLSRK-LGLDSIA--FGYLQTTFGVLQLLGGPVFGRFAD 84 Query: 456 WTQTYDIAFYFSGFCVLLGGFILLLAA 482 Q A F L ++LL AA Sbjct: 85 --QRGARAALTLSFLAALALYLLLAAA 109 >gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo sapiens] Length = 1791 Score = 34.3 bits (77), Expect = 0.28 Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 20/155 (12%) Query: 204 PEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGDWKQD--SLLHK------ 255 PE Y ++ E K + + ++ SE++ +T+ + K D S+L + Sbjct: 940 PEPEQQAYELHQENKKPTSQRVQSVEIDMFSEDEPHLTIQDPRKKSDVTSILSECSTIDL 999 Query: 256 ------NPTVTHTKEPETYKKKVAEQTYFCKQLAKRK--WQLYKNYCGETVALFKNKVFS 307 P + K+PE K + C + KRK W ++ N + K+ F Sbjct: 1000 QDGFGWLPEMVPKKQPERCLPKGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSWFE 1059 Query: 308 ALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFI 342 + I ++L G +L+ EDV + K +E + Sbjct: 1060 SFIIFVILLSSG----ALIFEDVHLENQPKIQELL 1090 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.142 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,516,169 Number of Sequences: 37866 Number of extensions: 864565 Number of successful extensions: 2599 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 2522 Number of HSP's gapped (non-prelim): 78 length of query: 509 length of database: 18,247,518 effective HSP length: 107 effective length of query: 402 effective length of database: 14,195,856 effective search space: 5706734112 effective search space used: 5706734112 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.