BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo sapiens] (1075 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho... 2201 0.0 gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 316 7e-86 gi|116284392 mucin 2 precursor [Homo sapiens] 120 7e-27 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 113 1e-24 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 113 1e-24 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 113 1e-24 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 113 1e-24 gi|163965366 nascent polypeptide-associated complex alpha subuni... 110 5e-24 gi|16554449 zonadhesin isoform 3 [Homo sapiens] 109 2e-23 gi|27881494 zonadhesin isoform 6 [Homo sapiens] 109 2e-23 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 102 2e-21 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 96 2e-19 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 93 1e-18 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 87 6e-17 gi|91982772 mucin 17 [Homo sapiens] 87 1e-16 gi|110349719 titin isoform N2-A [Homo sapiens] 84 7e-16 gi|222418647 mucin 7, secreted precursor [Homo sapiens] 83 1e-15 gi|222418649 mucin 7, secreted precursor [Homo sapiens] 83 1e-15 gi|222418645 mucin 7, secreted precursor [Homo sapiens] 83 1e-15 gi|150170670 piccolo isoform 2 [Homo sapiens] 82 3e-15 gi|150378539 piccolo isoform 1 [Homo sapiens] 82 3e-15 gi|151301154 mucin 6, gastric [Homo sapiens] 80 8e-15 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 80 1e-14 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 77 7e-14 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 77 1e-13 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 75 3e-13 gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 75 3e-13 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 75 4e-13 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 72 2e-12 gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 72 2e-12 >gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo sapiens] Length = 1075 Score = 2201 bits (5702), Expect = 0.0 Identities = 1075/1075 (100%), Positives = 1075/1075 (100%) Query: 1 MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPN 60 MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPN Sbjct: 1 MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPN 60 Query: 61 VKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTR 120 VKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTR Sbjct: 61 VKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTR 120 Query: 121 SRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQI 180 SRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQI Sbjct: 121 SRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQI 180 Query: 181 CPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVP 240 CPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVP Sbjct: 181 CPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVP 240 Query: 241 AYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMF 300 AYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMF Sbjct: 241 AYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMF 300 Query: 301 EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETT 360 EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETT Sbjct: 301 EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETT 360 Query: 361 LASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPP 420 LASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPP Sbjct: 361 LASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPP 420 Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR 480 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR Sbjct: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR 480 Query: 481 TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA 540 TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA Sbjct: 481 TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA 540 Query: 541 PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600 PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS Sbjct: 541 PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600 Query: 601 EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660 EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF Sbjct: 601 EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660 Query: 661 YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720 YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP Sbjct: 661 YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720 Query: 721 LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780 LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT Sbjct: 721 LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780 Query: 781 DFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840 DFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP Sbjct: 781 DFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840 Query: 841 PTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN 900 PTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN Sbjct: 841 PTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN 900 Query: 901 LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYS 960 LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYS Sbjct: 901 LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYS 960 Query: 961 ECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFL 1020 ECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFL Sbjct: 961 ECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFL 1020 Query: 1021 DGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW 1075 DGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW Sbjct: 1021 DGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW 1075 >gi|148806908 fibronectin type III domain containing 1 [Homo sapiens] Length = 1894 Score = 316 bits (810), Expect = 7e-86 Identities = 236/674 (35%), Positives = 314/674 (46%), Gaps = 86/674 (12%) Query: 470 PKRRPRPKPPRTKPERT--------TSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKI 521 P +RP P PP + P + SA T++P P P +TT AP S P + Sbjct: 1239 PVKRPLPPPPGSSPRASHVPSRLPPRSAATVSPVAGTHPWPQYTTRAP--PGHFSTTPML 1296 Query: 522 PLSPEVTHTK---PAPKQTPRAPPKPKTSPRPRI-----PQTQPVPKVPQRVTAKPKTSP 573 L + H + P +Q R + + RP + P + P QR+ P+ + Sbjct: 1297 SLRQRMMHARFRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPN-GQRIINGPQGT- 1354 Query: 574 SPEVSYTTPAPKDVLLPHKP-YPEVSQSEPAPLETRG-------IPFIPMISPSP----S 621 + + ++L + Y + S P ++ G + P++SP Sbjct: 1355 ----KWVVDLDRGLVLNAEGRYLQDSHGNPLRIKLGGDGRTIVDLEGTPVVSPDGLPLFG 1410 Query: 622 QEELQTTLEETDQST-----QEPF--------TTKIPRTTELAKTTQAPHRFYTTVRPRT 668 Q T L +P TT P TT TT P TT RP T Sbjct: 1411 QGRHGTPLANAQDKPILSLGGKPLVGLEVIKKTTHPPTTTMQPTTTTTPLPTTTTPRPTT 1470 Query: 669 SDKPHIRPGVKQAPR-PSGADRNVSVDSTHPTKKPGTRRPPLPP----RPTHPRRKPLPP 723 + + R P+ R + +T T P T P PP R + Sbjct: 1471 ATTRRTTTTRRTTTRRPTTTVRTTTRTTTTTTPTPTTPIPTCPPGTLERHDDDGNLIMSS 1530 Query: 724 NNV----TGKPGSAGIISSGPITTPPLR---------STPRPTGTPLERIETDIKQPTVP 770 N + + +G+ + + T T RP T E T +P Sbjct: 1531 NGIPECYAEEDEFSGLETDTAVPTEEAYVIYDEDYEFETSRPP-TTTEPSTTATTPRVIP 1589 Query: 771 ASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATE 830 G SS P E D G+ RF P+V Y+ K ++PCS+TD++ F + E Sbjct: 1590 EEGA-------ISSFPEEEFDLAGRKRFVAPYVTYLNKDPSAPCSLTDALDHFQVDSLDE 1642 Query: 831 ------GNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPL-NDTVTEYEVISRENGSFSG 883 + PPQ+ P N+TVV VEGC SFVI+DW+K D VT Y V S F Sbjct: 1643 IIPNDLKKSDLPPQHAPRNITVVAVEGCHSFVIVDWDKATPGDVVTGYLVYSASYEDFIR 1702 Query: 884 KNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPR-VSEPVS 942 S Q ++ T +ENLKPNT Y F+V+ +NP G GP+S +V+F TES +P V P Sbjct: 1703 NKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPHGYGPISPSVSFVTESDNPLLVVRP-- 1760 Query: 943 AGRDAIWTERPFNSD-SYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYN 1001 G + IW F D SY++C G+QYVKRTWY+KFVGV LCNSLRYKIYLSD+L FY+ Sbjct: 1761 PGGEPIWIPFAFKHDPSYTDCHGRQYVKRTWYRKFVGVVLCNSLRYKIYLSDNLKDTFYS 1820 Query: 1002 IGDQRGHGEDHCQFVDSFLDGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINY 1061 IGD G GEDHCQFVDS LDGRTG Q + LP +GY+R RQEPV+FG IG T Y Sbjct: 1821 IGDSWGRGEDHCQFVDSHLDGRTGPQSYVEALPTIQGYYRQYRQEPVRFGNIGFGTPYYY 1880 Query: 1062 VQWYECGTTIPGKW 1075 V WYECG +IPGKW Sbjct: 1881 VGWYECGVSIPGKW 1894 Score = 66.6 bits (161), Expect = 1e-10 Identities = 184/886 (20%), Positives = 312/886 (35%), Gaps = 148/886 (16%) Query: 39 LKVHINTTSDSILLKFLRP------SPNVKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAI 92 L+V + ++ D + + + P SP + G LLGYG + Y PL + + T I Sbjct: 162 LRVRVRSSDDRLSVAWKAPRLSGAKSPR-RSRGFLLGYGESGRKMNYVPLTRDER-THEI 219 Query: 93 VDAEPKYLIVVRPAPPPSQ------------KKSCSGKTRSRKPLQLVVGTLTPSSVFLS 140 + + VV SQ K+ S + P + V ++ SV +S Sbjct: 220 KKLASESVYVVSLQSMNSQGRSQPVYRAALTKRKISEEDELDVPDDISVRVMSSQSVLVS 279 Query: 141 WGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQICPATETIVENLKPNTVYEFG 200 W + + S R YT+RYREK + +W ++ ++ENL P+TVYEF Sbjct: 280 WVDPVLEKQKKVVAS-----RQYTVRYREKGELARWDYKQIANRRVLIENLIPDTVYEFA 334 Query: 201 VK--DNVEGGIWSKIFNHKTVVGSK----------KVNGK---IQSTYDQDHTVPAYVPR 245 V+ G WS +T + VNGK + +++D V Sbjct: 335 VRISQGERDGKWSTSVFQRTPESAPTTAPENLNVWPVNGKPTVVAASWDALPETEGKVKE 394 Query: 246 KLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASL------M 299 ++ + +P P G L + PG +TT L L + Sbjct: 395 YIL-----------------SYAPALKPFGAKSLTY---PG--DTTSALVDGLQPGERYL 432 Query: 300 FEISDALKTQL---AKNETLALPAESKT--------------PEVEKISAR-PTTVTPET 341 F+I + L +K +A+P SK PE S R P + + Sbjct: 433 FKIRATNRRGLGPHSKAFIVAMPTTSKADVEQNTEDNGKPEKPEPSSPSPRAPASSQHPS 492 Query: 342 VPRSTKPTTSS--ALDVSETTLASS---EKPWIVPTAKISEDSKVLQPQTATYDVFSSPT 396 VP S + + LD+ LA+ KP + AK +E+ + + + S Sbjct: 493 VPASPQGRNAKDLLLDLKNKILANGGAPRKPQL--RAKKAEELDLQSTEITGEEELGS-- 548 Query: 397 TSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPT 456 ++ +S S T R L P + ++ P T + P +P++ + T Sbjct: 549 -REDSPMSPSDTQDQKRTLRP-PSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLAT 606 Query: 457 TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFIS 516 P P S ++P + +P S S E + P K F Sbjct: 607 QPRPGAPPSASASPAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVGSLHP-KGAF-- 663 Query: 517 LKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPE 576 +P+ LSP +Q+P + + ++S P P + P A+ +S S Sbjct: 664 AQPRPALSPS--------RQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAP 715 Query: 577 VSYTTP--APKDVLLPHKPYPEVSQS------EPAPLETRGIPFIPMISPS-----PSQE 623 S +P LLP +P+ S E AP P +S S S+ Sbjct: 716 PSRLSPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRT 775 Query: 624 ELQTTLEETD-----QSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGV 678 ++ E +D +E + T + + A F+ KP G Sbjct: 776 QVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHL-----LRHKPFAANGR 830 Query: 679 KQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPR-PTHPR-RKPLPPNNVTGKPGSAGII 736 + G + S+ + P P +P +HP+ + + KP A ++ Sbjct: 831 SPSRFSIGRGPRLQPSSSPQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVV 890 Query: 737 SSGPITTPPLRSTPRPTGTPLERIETDIKQ-PTVPASGEELENITDFSSSPTRETDPLGK 795 + P + P+ R D+++ P AS E I + S +T P GK Sbjct: 891 ND---------HVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPQGK 941 Query: 796 PRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPP 841 + +Q+ ++ D+ PK + + + P PP Sbjct: 942 YSSLASKAQDVQQSTDA-----DTEGHSPKAQPGSTDRHASPARPP 982 Score = 45.8 bits (107), Expect = 2e-04 Identities = 77/342 (22%), Positives = 134/342 (39%), Gaps = 38/342 (11%) Query: 429 PRATLAPSETPFVPQKLE--------IFTSPEMQPTTPAPQQTTSIPSTPKRRPRPK--- 477 P++T+ P VP + I E + PA +PS+ R+P + Sbjct: 849 PQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSS-SRQPISRGWE 907 Query: 478 PPRTKPERTTSAGTITPKISKSPEPTWTTPAP-GKTQFISLKPK-IPLSPEVTHTKPAPK 535 R P+R S P I ++P+ T P GK ++ K + + S + +PK Sbjct: 908 DLRRSPQRGASLHRKEP-IPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPK 966 Query: 536 QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVT--AKPKTSPSPEVS----YTTPAPKDV-L 588 P + + + RP ++Q P VP+R+T P+ P P V+ + P +D Sbjct: 967 AQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 1026 Query: 589 LPHKPYPEVSQS-EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT 647 P +P ++Q+ P P + S+ L T L+ D+ Q + + Sbjct: 1027 SPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDD---S 1083 Query: 648 TEL-AKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706 TE+ A+ +AP R + P +Q P+GA H +++ Sbjct: 1084 TEVEAQDVRAPAH-----AARAKEAAASLPKHQQVESPTGA----GAGGDHRSQRGHAAS 1134 Query: 707 PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRS 748 P P RP P+ + P+ PG + S P+++ +S Sbjct: 1135 PARPSRPGGPQSRARVPSRAA--PGKSEPPSKRPLSSKSQQS 1174 Score = 37.4 bits (85), Expect = 0.077 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 453 MQPTT---PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509 MQPTT P P TT P+T R RT R T+ T + + + PT TTP P Sbjct: 1451 MQPTTTTTPLPTTTTPRPTTATTRRTTTTRRTTTRRPTTTVRTTTRTTTTTTPTPTTPIP 1510 Score = 37.0 bits (84), Expect = 0.10 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Query: 835 SPPQNPPTNLTVVTVEGCPSFVILDWEK-PLNDTVTEYEVISRENGSFSGKNKSIQMTNQ 893 S P P NL V V G P+ V W+ P + + ++S KS+ Sbjct: 357 SAPTTAPENLNVWPVNGKPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGD 416 Query: 894 TFST-VENLKPNTSYEFQVKPKNPLGEGPVSNT--VAFSTES 932 T S V+ L+P Y F+++ N G GP S VA T S Sbjct: 417 TTSALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTS 458 Score = 36.2 bits (82), Expect = 0.17 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 10/80 (12%) Query: 424 RTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP 483 +T P T+ P+ T T+P TTP P T+ +T RR + P T Sbjct: 1442 KTTHPPTTTMQPTTT----------TTPLPTTTTPRPTTATTRRTTTTRRTTTRRPTTTV 1491 Query: 484 ERTTSAGTITPKISKSPEPT 503 TT T T +P PT Sbjct: 1492 RTTTRTTTTTTPTPTTPIPT 1511 Score = 34.7 bits (78), Expect = 0.50 Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 33/157 (21%) Query: 454 QPTTPA-PQQTTSIPSTPKRRP-RPKPPRTKPERTTSAGTITPK---------------- 495 +P+ P PQ +PS + P + +PP +P + S +++ + Sbjct: 1137 RPSRPGGPQSRARVPS--RAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGFFKGGKED 1194 Query: 496 ISKSPEPTW---TTPAPGKTQFISL-----KPKIPLSPEVTHTKPAPKQTPRAPPKPKTS 547 + S P W +TP GK SL +P I L+P P + P P P +S Sbjct: 1195 LLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLP---PPPGSS 1251 Query: 548 PRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 584 PR ++ P+ V+ T P P+ YTT AP Sbjct: 1252 PRASHVPSRLPPRSAATVSPVAGTHPWPQ--YTTRAP 1286 Score = 30.4 bits (67), Expect = 9.4 Identities = 14/28 (50%), Positives = 16/28 (57%) Query: 175 KWIFQICPATETIVENLKPNTVYEFGVK 202 KW Q T +ENLKPNT Y F V+ Sbjct: 1704 KWSTQASSVTHLPIENLKPNTRYYFKVQ 1731 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 120 bits (301), Expect = 7e-27 Identities = 114/396 (28%), Positives = 147/396 (37%), Gaps = 38/396 (9%) Query: 334 PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFS 393 P T TP P ST + TT ++ P P+ I+ + P T T Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT--TTTTPPPTTTPSPPI 1458 Query: 394 SPTTSDEPEISDS--YTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSP 451 S TT+ P + S T S PP T+ T P T +P T + T P Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518 Query: 452 EMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP-ERTTSAGTITPKISKSPEPTWTTPAPG 510 TTP+P TT+ +TP P PP T P TS T+ P + SP PT TT P Sbjct: 1519 --PTTTPSPPTTTT--TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574 Query: 511 KTQFISLKPKIPLSPEVTHTKPAPKQTPRAP------PKPKTSPRPRIPQTQPVPKVPQR 564 T P P +T T P P TP P P P T+P P P T P+ Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP--PTTTPITPPTST 1632 Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624 T P T+PSP + TT P P P + + P+ T P P +PS Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTT----TPSPPTTTTPSPPITTTTTP-PPTTTPS----- 1682 Query: 625 LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRP 684 + + T TT P TT + T TT P ++ P P P P Sbjct: 1683 --SPITTTPSPPTTTMTTPSPTTTPSSPIT-------TTTTPSSTTTPSPPPTTMTTPSP 1733 Query: 685 SGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720 + + +T T P T PL P P P Sbjct: 1734 TTTPSPPT--TTMTTLPPTTTSSPLTTTPLPPSITP 1767 Score = 117 bits (294), Expect = 4e-26 Identities = 155/649 (23%), Positives = 213/649 (32%), Gaps = 120/649 (18%) Query: 319 PAESKTPEVEKISARPTTVTPE---TVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375 P + +P + P T TP T + PTT+ + +S TT PT Sbjct: 1418 PTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTP 1477 Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISD-----SYTATSDRILDSIPPKTSRTLEQPR 430 S + P T T PTT+ P + + T T PP T+ T P Sbjct: 1478 SPPTTTPSPPTTTTTT-PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536 Query: 431 ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490 T +P T + T P TTP+P TT+ P P P P T P T Sbjct: 1537 TTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITT 1593 Query: 491 TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP 550 T P + PT TT P T S P++P + T P TP PP T+P P Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653 Query: 551 RI-----PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP-----YPEVSQS 600 T P P + T P T+PS ++ T P + P P + + Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713 Query: 601 EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660 P+ T P M +PSP+ T T +T P TT P TT + P F Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPT---TTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770 Query: 661 --YTTVRPRT-------------SDKPHI-RPG--------------------------- 677 ++T P T S KP+ +PG Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPD 1830 Query: 678 --VKQAPRPSGADRNVSVDSTHPTKKPG-------------------------TRRPPLP 710 + Q + D +V + + +KPG T Sbjct: 1831 VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTT 1890 Query: 711 PRPTHPRRKPL-PPNNVTGKPGSAGIISSGPITTP-----PLRSTPRPTGTPLER----I 760 PT P P+ VT P G + P TTP + TP PTGT Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1948 Query: 761 ETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSV 820 T PT +G + T +++ T P Q P +P + T +V Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPITTTTTV 1999 Query: 821 KRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 P T+ +P P T T VT P+ P+ T T Sbjct: 2000 TPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2044 Score = 114 bits (285), Expect = 5e-25 Identities = 151/594 (25%), Positives = 213/594 (35%), Gaps = 71/594 (11%) Query: 321 ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-----TLASSEKPWIVPTAKI 375 E+ TP TTVTP P T+ T++ + + T T ++ P P Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1950 Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTL---EQPRAT 432 + + P T T ++P T+ ++ + T T + + P T+ T+ P T Sbjct: 1951 TTVTPTPTP-TGTQTPTTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008 Query: 433 LAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPERTT 487 P+ TP +P PT TT I +T P P P P T P TT Sbjct: 2009 QTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2065 Query: 488 SAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQ 536 + T TP + + PT T TP P TQ + P I + VT T P Q Sbjct: 2066 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQ 2124 Query: 537 TPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLP 590 TP P T +P P QT + T P +P+ + TTP + Sbjct: 2125 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2184 Query: 591 HKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPFTT 642 P P +Q+ T P +P+ +Q T T T TQ P TT Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244 Query: 643 KIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTH 697 I TT + T TQ P T + T+ P P Q P + +V Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--- 2299 Query: 698 PTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGT 755 PT P GT+ P P T P P T P + I ++ +T TP T PT T Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359 Query: 756 PLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCS 815 P+ T PT +G + T +++ T P Q P +P + Sbjct: 2360 PI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPIT 2408 Query: 816 ITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 T +V P T+ +P P T T VT P+ P+ T T Sbjct: 2409 TTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458 Score = 112 bits (281), Expect = 1e-24 Identities = 149/580 (25%), Positives = 207/580 (35%), Gaps = 68/580 (11%) Query: 333 RPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVF 392 +PTT+T T T PTT+ + T + PT + + P T T Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGT 1939 Query: 393 SSPTT---SDEPEISDSYTATSDRILDSIPPKTSRTL---EQPRATLAPSETPFVPQKLE 446 +PTT + ++ + T T + + P T+ T+ P T P+ TP Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT- 1998 Query: 447 IFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPERTTSAGTITPKISKSPE 501 +P PT TT I +T P P P P T P TT+ T TP + + Sbjct: 1999 --VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2056 Query: 502 PTWT----------TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPRAPPKPKT---- 546 PT T TP P TQ + P I + VT T P QTP P T Sbjct: 2057 PTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115 Query: 547 -SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLPHKPYPEVSQSEPAP 604 +P P QT + T P +P+ + TTP + P P +Q+ Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175 Query: 605 LETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPFTTKIPRTTELAKT--- 653 T P +P+ +Q T T T TQ P TT I TT + T Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2235 Query: 654 --TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKP-GTRRPPLP 710 TQ P T + T+ P P Q P + +V PT P GT+ P Sbjct: 2236 TGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQTPTTT 2290 Query: 711 PRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPLERIETDIKQPTV 769 P T P P T P + I ++ +T TP T PT TP+ T PT Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPTP 2348 Query: 770 PASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEAT 829 +G + T +++ T P Q P +P + T +V P T Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPITTTTTVTPTPTPTGT 2399 Query: 830 EGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 + +P P T T VT P+ P+ T T Sbjct: 2400 Q----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2435 Score = 112 bits (281), Expect = 1e-24 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P ++TP I+ TTVTP P T+ T++ + + T P PT Sbjct: 2120 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 2170 Query: 379 SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434 + P T T V +PT T + + T T+ P T P T+ Sbjct: 2171 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2230 Query: 435 PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481 P+ TP P I T+ + PT P P TT I +T P P P P T Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289 Query: 482 KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530 P TT+ T TP + + PT T TP P TQ + P I + VT T Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 2348 Query: 531 KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408 Query: 585 KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636 + P P +Q+ T P +P+ +Q T T T T Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468 Query: 637 QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691 Q P TT I TT + T TQ P T + T+ P P Q P + Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526 Query: 692 SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749 +V PT P GT+ P P T P P T P + I ++ +T TP T Sbjct: 2527 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583 Query: 750 PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809 PT TP+ T PT +G + T +++ T P Q P Sbjct: 2584 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 2632 Query: 810 DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +P + T +V P T+ +P P T T VT P+ P+ T T Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688 Score = 112 bits (281), Expect = 1e-24 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P ++TP I+ TTVTP P T+ T++ + + T P PT Sbjct: 2442 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 2492 Query: 379 SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434 + P T T V +PT T + + T T+ P T P T+ Sbjct: 2493 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552 Query: 435 PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481 P+ TP P I T+ + PT P P TT I +T P P P P T Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611 Query: 482 KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530 P TT+ T TP + + PT T TP P TQ + P I + VT T Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 2670 Query: 531 KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730 Query: 585 KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636 + P P +Q+ T P +P+ +Q T T T T Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790 Query: 637 QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691 Q P TT I TT + T TQ P T + T+ P P Q P + Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 2848 Query: 692 SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749 +V PT P GT+ P P T P P T P + I ++ +T TP T Sbjct: 2849 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905 Query: 750 PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809 PT TP+ T PT +G + T +++ T P Q P Sbjct: 2906 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 2954 Query: 810 DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +P + T +V P T+ +P P T T VT P+ P+ T T Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010 Score = 112 bits (281), Expect = 1e-24 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P ++TP I+ TTVTP P T+ T++ + + T P PT Sbjct: 2764 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 2814 Query: 379 SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434 + P T T V +PT T + + T T+ P T P T+ Sbjct: 2815 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874 Query: 435 PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481 P+ TP P I T+ + PT P P TT I +T P P P P T Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933 Query: 482 KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530 P TT+ T TP + + PT T TP P TQ + P I + VT T Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 2992 Query: 531 KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052 Query: 585 KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636 + P P +Q+ T P +P+ +Q T T T T Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112 Query: 637 QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691 Q P TT I TT + T TQ P T + T+ P P Q P + Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170 Query: 692 SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749 +V PT P GT+ P P T P P T P + I ++ +T TP T Sbjct: 3171 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227 Query: 750 PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809 PT TP+ T PT +G + T +++ T P Q P Sbjct: 3228 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 3276 Query: 810 DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +P + T +V P T+ +P P T T VT P+ P+ T T Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332 Score = 112 bits (281), Expect = 1e-24 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P ++TP I+ TTVTP P T+ T++ + + T P PT Sbjct: 3086 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 3136 Query: 379 SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434 + P T T V +PT T + + T T+ P T P T+ Sbjct: 3137 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3196 Query: 435 PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481 P+ TP P I T+ + PT P P TT I +T P P P P T Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255 Query: 482 KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530 P TT+ T TP + + PT T TP P TQ + P I + VT T Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 3314 Query: 531 KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374 Query: 585 KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636 + P P +Q+ T P +P+ +Q T T T T Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434 Query: 637 QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691 Q P TT I TT + T TQ P T + T+ P P Q P + Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492 Query: 692 SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749 +V PT P GT+ P P T P P T P + I ++ +T TP T Sbjct: 3493 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549 Query: 750 PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809 PT TP+ T PT +G + T +++ T P Q P Sbjct: 3550 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 3598 Query: 810 DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +P + T +V P T+ +P P T T VT P+ P+ T T Sbjct: 3599 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654 Score = 112 bits (281), Expect = 1e-24 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P ++TP I+ TTVTP P T+ T++ + + T P PT Sbjct: 3408 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 3458 Query: 379 SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434 + P T T V +PT T + + T T+ P T P T+ Sbjct: 3459 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518 Query: 435 PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481 P+ TP P I T+ + PT P P TT I +T P P P P T Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577 Query: 482 KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530 P TT+ T TP + + PT T TP P TQ + P I + VT T Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 3636 Query: 531 KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 3637 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696 Query: 585 KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636 + P P +Q+ T P +P+ +Q T T T T Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3756 Query: 637 QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691 Q P TT I TT + T TQ P T + T+ P P Q P + Sbjct: 3757 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814 Query: 692 SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749 +V PT P GT+ P P T P P T P + I ++ +T TP T Sbjct: 3815 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3871 Query: 750 PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809 PT TP+ T PT +G + T +++ T P Q P Sbjct: 3872 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 3920 Query: 810 DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +P + T +V P T+ +P P T T VT P+ P+ T T Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3976 Score = 108 bits (270), Expect = 3e-23 Identities = 151/577 (26%), Positives = 203/577 (35%), Gaps = 83/577 (14%) Query: 335 TTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED---SKVLQPQTATYD- 390 TT+T T P + TT++ S T L+++ K + + I+ED S T+D Sbjct: 1269 TTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG 1328 Query: 391 VFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPF--------VP 442 V +P + + D + + L+ + K + + +E F Sbjct: 1329 VCGAPEDIECRSVKDPHLS-----LEQLGQKVQCDVSV--GFICKNEDQFGNGPFGLCYD 1381 Query: 443 QKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE-RTTSAGTITPKISKSP- 500 K+ + M P T+ PS P PP T P TT+ T P + SP Sbjct: 1382 YKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1441 Query: 501 ------EPTWTTPAPGKTQFISLKPKIPLSPEVT-----HTKPAPKQTPRAPPKPKTSPR 549 P TTP+P + + P SP T T P+P T P P T+P Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501 Query: 550 PRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609 P P T P+ T P T+PSP + TT P P P + P T Sbjct: 1502 P--PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTT----TPSPPTTTPITPPTSTTT 1555 Query: 610 IPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTV-RPRT 668 +P P +PSP T +T P TT P TT TT +P TT P T Sbjct: 1556 LP--PTTTPSP---------PPTTTTTPPPTTTPSPPTT----TTPSPPTITTTTPPPTT 1600 Query: 669 SDKPHIRPGVKQAP--RPSGADRNVSVDSTHPTKKPGTRRPPLPPRPT---HPRRKPLPP 723 + P P PS T T P T P PP T P P PP Sbjct: 1601 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660 Query: 724 NNVTGKPGSAGIISSGPITTP--PLRSTPRP------TGTPLERIETDIKQPTVPASGEE 775 T P + P TTP P+ +TP P T +P + I T P+S Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS--- 1717 Query: 776 LENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---DNSPCSITDSVKRFPKEEATEGN 832 T S PT T P P P +SP + T + + Sbjct: 1718 ---TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774 Query: 833 ATSP--PQNPPTNLTVVTVEGCPSFVILDWEKPLNDT 867 T+P P P N T G P+F KP DT Sbjct: 1775 TTTPTTPCVPLCNWTGWLDSGKPNF-----HKPGGDT 1806 Score = 105 bits (262), Expect = 2e-22 Identities = 151/569 (26%), Positives = 206/569 (36%), Gaps = 79/569 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P ++TP I+ TTVTP P T+ T++ + + T P PT Sbjct: 3730 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 3780 Query: 379 SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434 + P T T V +PT T + + T T+ P T P T+ Sbjct: 3781 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840 Query: 435 PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481 P+ TP P I T+ + PT P P TT I +T P P P P T Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3899 Query: 482 KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530 P TT+ T TP + + PT T TP P TQ + P I + VT T Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 3958 Query: 531 KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 3959 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018 Query: 585 KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKI 644 + P P +Q+ T I ++P+P T TQ P TT I Sbjct: 4019 TTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTP-----------TPTGTQTPTTTPI 4063 Query: 645 PRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPT 699 TT + T TQ P T + T+ P P Q P + +V PT Sbjct: 4064 TTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PT 4118 Query: 700 KKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPL 757 P GT+ P P T P P T P + I ++ +T TP T PT TP+ Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4178 Query: 758 ERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSIT 817 T PT +G + T S++P E P P Q ++ +T Sbjct: 4179 --TTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP----PESSTPQTSRSTSSPLT 4232 Query: 818 DSVKRFPK-EEATEGNATSPPQNPPTNLT 845 +S A E +T+PP P T Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTT 4261 Score = 99.8 bits (247), Expect = 1e-20 Identities = 141/531 (26%), Positives = 187/531 (35%), Gaps = 85/531 (16%) Query: 381 VLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPF 440 V QP T T +PT I+ + T T P T P T P+ TP Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVT--------PTPT------PTGTQTPTTTP- 1923 Query: 441 VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRTKPERTTSAG 490 I T+ + PT P P TT I +T P P P P T P TT+ Sbjct: 1924 ------ITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1976 Query: 491 TITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPR 539 T TP + + PT T TP P TQ + P I + VT T P QTP Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPT 2035 Query: 540 APPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLPHKP 593 P T +P P QT + T P +P+ + TTP + P Sbjct: 2036 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2095 Query: 594 YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPFTTKIP 645 P +Q+ T P +P+ +Q T T T TQ P TT I Sbjct: 2096 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155 Query: 646 RTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700 TT + T TQ P T + T+ P P Q P + +V PT Sbjct: 2156 TTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTP 2210 Query: 701 KP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPLE 758 P GT+ P P T P P T P + I ++ +T TP T PT TP+ Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2269 Query: 759 RIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITD 818 T PT +G + T +++ T P Q P +P + T Sbjct: 2270 -TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPITTTT 2319 Query: 819 SVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +V P T+ +P P T T VT P+ P+ T T Sbjct: 2320 TVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2366 Score = 99.4 bits (246), Expect = 2e-20 Identities = 132/520 (25%), Positives = 186/520 (35%), Gaps = 66/520 (12%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-----TLASSEKPWIVPTA 373 P ++TP I+ TTVTP P T+ T++ + + T T ++ P P Sbjct: 3822 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880 Query: 374 KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ---PR 430 + + P T T ++P T+ ++ + T T + + P T+ T+ P Sbjct: 3881 TTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3938 Query: 431 ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPER 485 T P+ TP +P PT TT I +T P P P P T P Sbjct: 3939 GTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3995 Query: 486 TTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHTK-PAP 534 TT+ T TP + + PT T TP P TQ + P I + VT T P Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTG 4054 Query: 535 KQTPRAPPKPKTS-----PRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVL 588 QTP P T+ P P QT + T P +P+ + TTP Sbjct: 4055 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4114 Query: 589 LPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPF 640 + P P +Q+ T P +P+ +Q T T T TQ P Sbjct: 4115 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174 Query: 641 TTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700 TT I TT + T P T TS P I P P + S ++ P Sbjct: 4175 TTPITTTTTVTPTP-TPTGTQTGPPTHTSTAP-IAELTTSNPPPESSTPQTSRSTSSPLT 4232 Query: 701 KPGTRRPPLPPR----PTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTP 756 + T LPP T P P P +G G +PP +T P GTP Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----------GHTLSPPPSTTTSPPGTP 4282 Query: 757 LERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKP 796 T P++ + T +S+ T PL P Sbjct: 4283 TRGTTTGSSSAPTPSTVQ-----TTTTSAWTPTPTPLSTP 4317 Score = 79.0 bits (193), Expect = 2e-14 Identities = 107/419 (25%), Positives = 147/419 (35%), Gaps = 54/419 (12%) Query: 484 ERTTSAGTITPKISKSPEPTWT-----------TPAPGKTQFISLKPKIPLSPEVTHT-K 531 E T T+T +++P P T TP P TQ + P I + VT T Sbjct: 1877 ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 1935 Query: 532 PAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPK 585 P QTP P T +P P QT + T P +P+ + TTP Sbjct: 1936 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1995 Query: 586 DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQ 637 + P P +Q+ T P +P+ +Q T T T TQ Sbjct: 1996 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2055 Query: 638 EPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692 P TT I TT + T TQ P T + T+ P P Q P + + Sbjct: 2056 TPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2113 Query: 693 VDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTP 750 V PT P GT+ P P T P P T P + I ++ +T TP T Sbjct: 2114 VT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2170 Query: 751 RPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPD 810 PT TP+ T PT +G + T +++ T P Q P Sbjct: 2171 TPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPT 2219 Query: 811 NSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869 +P + T +V P T+ +P P T T VT P+ P+ T T Sbjct: 2220 TTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274 Score = 72.4 bits (176), Expect = 2e-12 Identities = 124/482 (25%), Positives = 173/482 (35%), Gaps = 101/482 (20%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-----TLASSEKPWIVPTA 373 P ++TP I+ TTVTP P T+ T++ + + T T ++ P P Sbjct: 3960 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018 Query: 374 KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ---PR 430 + + P T T ++P T+ ++ + T T + + P T+ T+ P Sbjct: 4019 TTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076 Query: 431 ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPER 485 T P+ TP +P PT TT I +T P P P P T P Sbjct: 4077 GTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133 Query: 486 TTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHTKPAPK 535 TT+ T TP + + PT T TP P TQ + P I + VT T P P Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPT-PTPT 4191 Query: 536 QTPRAPPK-PKTSPRPRIPQTQPVPK--VPQ--RVTAKPKTS---------PSPEVSYTT 581 T PP T+P + + P P+ PQ R T+ P T P+ E++ T Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA 4251 Query: 582 P-----APKDVLLPH--KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQ 634 P AP H P P + S P TRG +P+PS +QTT Sbjct: 4252 PPSTPTAPTTTSGGHTLSPPPSTTTSPPGT-PTRGTTTGSSSAPTPST--VQTTTTSAWT 4308 Query: 635 STQEPFTT-KIPRTTELAK-------------TTQAPHR--------------------- 659 T P +T I RTT L T AP Sbjct: 4309 PTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCT 4368 Query: 660 --FYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPR 717 FY P T P PS + S S+ P+K +PP P PR Sbjct: 4369 LEFYNWSCPSTPSP---------TPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPR 4419 Query: 718 RK 719 ++ Sbjct: 4420 QE 4421 Score = 36.6 bits (83), Expect = 0.13 Identities = 58/259 (22%), Positives = 85/259 (32%), Gaps = 57/259 (22%) Query: 310 LAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWI 369 +A+ T P ES TP+ + ++ P T TTL S+ P I Sbjct: 4206 IAELTTSNPPPESSTPQTSRSTSSPLT--------------------ESTTLLSTLPPAI 4245 Query: 370 VPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQP 429 E + P T T +PTT+ S +T + + PP T Sbjct: 4246 -------EMTSTAPPSTPT-----APTTT-----SGGHTLSPPPSTTTSPPGT-----PT 4283 Query: 430 RATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSA 489 R T S + P ++ T+ P TP P T SI T RP P Sbjct: 4284 RGTTTGSSSAPTPSTVQTTTTSAWTP-TPTPLSTPSIIRTTGLRP-------YPSSVLIC 4335 Query: 490 GTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLS------PEVTHTKPAPKQTPRAPPK 543 + E + F++ L P P P ++ P K Sbjct: 4336 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK 4395 Query: 544 PKTSPRPRIPQTQPVPKVP 562 P ++P P T+P P+ P Sbjct: 4396 PSSTPSKPTPGTKP-PECP 4413 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 113 bits (282), Expect = 1e-24 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374 P S P + TV ET + + TT++ + D E T ++ E I T+ Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185 Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420 ++ SKVL T + + +PTT EP + T T+ + + P Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245 Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472 + + T + T P ++ T E PTT PAP T S P+TPK Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305 Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518 +P P K T+ TP K P PT PA P T Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365 Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568 P P P T TK PAP T AP K P P ++ P PK P T K Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 424 Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625 +P E + TTP P +P P + EPAP T + P P +P+ +E Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483 Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679 TT ++ +T E P T + P T ELA TT T P + P Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 543 Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739 + P P+ P P P+ T P P KP + Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 600 Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792 P TT ST P PT TP T K+P P + +E T ++PT +P Sbjct: 601 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 658 Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839 L KGP KP +P + ++ PKE A + T+P Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 716 Query: 840 PPTNLTVVT 848 PPT V T Sbjct: 717 PPTTSEVST 725 Score = 92.0 bits (227), Expect = 3e-18 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%) Query: 290 TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345 TT K PA + + + A T + P K P + P TP+ T P+ Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 441 Query: 346 TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400 PTT + E +++KP PT E + +TA T +PTT ++ Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 498 Query: 401 -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 P + T+ L P+ T T E+P T + P P++ T E PTT Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558 Query: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508 P P+TPK P T P TPK + + EPT TT Sbjct: 559 PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614 Query: 509 PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567 P T P P P T K PAP P P P P+ +P PK T Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 673 Query: 568 KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611 K TS P+P E + TTP P KP P ++ P P T+ P Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 732 Query: 612 FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663 SP S EL + T + + S +EP TTK P T+ TT A R T Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792 Query: 664 VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723 T+ P + K+ + + +T T + P + T + L P Sbjct: 793 TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 849 Query: 724 NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783 T K ITT + + P T P +R A+ + + T Sbjct: 850 KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 894 Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843 PT P PR + P + S + R EA T P Q P + Sbjct: 895 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 952 Query: 844 LTVV 847 L V Sbjct: 953 LVEV 956 Score = 50.4 bits (119), Expect = 9e-06 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%) Query: 291 TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347 T K PA+ E++ K + + + P + P++ K +A T T E+ +T+ Sbjct: 766 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 825 Query: 348 PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407 T+++ D + + + + + P K++ K + T ++ + P + +P+ Sbjct: 826 VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 876 Query: 408 TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459 AT+ + P K ++ ++P +T P P V P+K+ T PE+ PT+ Sbjct: 877 -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 934 Query: 460 PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519 + + P + P K P+ + G A G+T + L+P Sbjct: 935 AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 977 Query: 520 KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558 + PEVT P PR P + P S I +PV Sbjct: 978 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1017 Score = 46.6 bits (109), Expect = 1e-04 Identities = 88/394 (22%), Positives = 132/394 (33%), Gaps = 50/394 (12%) Query: 568 KPKTSPSPEVSYTTPAPKD-----VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQ 622 K K +P P V + D V P + ++ +P T P I+P PS Sbjct: 75 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSL 130 Query: 623 EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPG 677 T +ET + + T + TT K T + TT T + + P Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 190 Query: 678 VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIIS 737 K +P+ T K P P PT P+ P + T K + I Sbjct: 191 SKVLAKPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 238 Query: 738 SGPITTP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPL 793 S P TTP P + PT TP E T K+P P + +E T +PT Sbjct: 239 SAP-TTPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAP 295 Query: 794 GKPRFKGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVV 847 P+ P P + +P + + PKE A T+ A + P+ P Sbjct: 296 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355 Query: 848 TVEGCPSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTS 906 P ++P T E ++E + K + T +T + P T+ Sbjct: 356 PAPTTP-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408 Query: 907 YEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP 940 PK P P + T +P + P Sbjct: 409 KSAPTTPKEP---SPTTTKEPAPTTPKEPAPTTP 439 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 113 bits (282), Expect = 1e-24 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374 P S P + TV ET + + TT++ + D E T ++ E I T+ Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226 Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420 ++ SKVL T + + +PTT EP + T T+ + + P Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286 Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472 + + T + T P ++ T E PTT PAP T S P+TPK Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346 Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518 +P P K T+ TP K P PT PA P T Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406 Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568 P P P T TK PAP T AP K P P ++ P PK P T K Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 465 Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625 +P E + TTP P +P P + EPAP T + P P +P+ +E Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524 Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679 TT ++ +T E P T + P T ELA TT T P + P Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 584 Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739 + P P+ P P P+ T P P KP + Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 641 Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792 P TT ST P PT TP T K+P P + +E T ++PT +P Sbjct: 642 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 699 Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839 L KGP KP +P + ++ PKE A + T+P Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 757 Query: 840 PPTNLTVVT 848 PPT V T Sbjct: 758 PPTTSEVST 766 Score = 92.0 bits (227), Expect = 3e-18 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%) Query: 290 TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345 TT K PA + + + A T + P K P + P TP+ T P+ Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 482 Query: 346 TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400 PTT + E +++KP PT E + +TA T +PTT ++ Sbjct: 483 PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 539 Query: 401 -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 P + T+ L P+ T T E+P T + P P++ T E PTT Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599 Query: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508 P P+TPK P T P TPK + + EPT TT Sbjct: 600 PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655 Query: 509 PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567 P T P P P T K PAP P P P P+ +P PK T Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 714 Query: 568 KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611 K TS P+P E + TTP P KP P ++ P P T+ P Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 773 Query: 612 FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663 SP S EL + T + + S +EP TTK P T+ TT A R T Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833 Query: 664 VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723 T+ P + K+ + + +T T + P + T + L P Sbjct: 834 TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 890 Query: 724 NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783 T K ITT + + P T P +R A+ + + T Sbjct: 891 KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 935 Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843 PT P PR + P + S + R EA T P Q P + Sbjct: 936 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 993 Query: 844 LTVV 847 L V Sbjct: 994 LVEV 997 Score = 50.4 bits (119), Expect = 9e-06 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%) Query: 291 TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347 T K PA+ E++ K + + + P + P++ K +A T T E+ +T+ Sbjct: 807 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 866 Query: 348 PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407 T+++ D + + + + + P K++ K + T ++ + P + +P+ Sbjct: 867 VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 917 Query: 408 TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459 AT+ + P K ++ ++P +T P P V P+K+ T PE+ PT+ Sbjct: 918 -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 975 Query: 460 PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519 + + P + P K P+ + G A G+T + L+P Sbjct: 976 AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 1018 Query: 520 KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558 + PEVT P PR P + P S I +PV Sbjct: 1019 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1058 Score = 46.6 bits (109), Expect = 1e-04 Identities = 88/394 (22%), Positives = 132/394 (33%), Gaps = 50/394 (12%) Query: 568 KPKTSPSPEVSYTTPAPKD-----VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQ 622 K K +P P V + D V P + ++ +P T P I+P PS Sbjct: 116 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSL 171 Query: 623 EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPG 677 T +ET + + T + TT K T + TT T + + P Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 231 Query: 678 VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIIS 737 K +P+ T K P P PT P+ P + T K + I Sbjct: 232 SKVLAKPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 279 Query: 738 SGPITTP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPL 793 S P TTP P + PT TP E T K+P P + +E T +PT Sbjct: 280 SAP-TTPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAP 336 Query: 794 GKPRFKGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVV 847 P+ P P + +P + + PKE A T+ A + P+ P Sbjct: 337 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396 Query: 848 TVEGCPSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTS 906 P ++P T E ++E + K + T +T + P T+ Sbjct: 397 PAPTTP-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449 Query: 907 YEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP 940 PK P P + T +P + P Sbjct: 450 KSAPTTPKEP---SPTTTKEPAPTTPKEPAPTTP 480 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 113 bits (282), Expect = 1e-24 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374 P S P + TV ET + + TT++ + D E T ++ E I T+ Sbjct: 219 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278 Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420 ++ SKVL T + + +PTT EP + T T+ + + P Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338 Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472 + + T + T P ++ T E PTT PAP T S P+TPK Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398 Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518 +P P K T+ TP K P PT PA P T Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458 Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568 P P P T TK PAP T AP K P P ++ P PK P T K Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 517 Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625 +P E + TTP P +P P + EPAP T + P P +P+ +E Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576 Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679 TT ++ +T E P T + P T ELA TT T P + P Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636 Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739 + P P+ P P P+ T P P KP + Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 693 Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792 P TT ST P PT TP T K+P P + +E T ++PT +P Sbjct: 694 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 751 Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839 L KGP KP +P + ++ PKE A + T+P Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809 Query: 840 PPTNLTVVT 848 PPT V T Sbjct: 810 PPTTSEVST 818 Score = 92.0 bits (227), Expect = 3e-18 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%) Query: 290 TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345 TT K PA + + + A T + P K P + P TP+ T P+ Sbjct: 476 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 534 Query: 346 TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400 PTT + E +++KP PT E + +TA T +PTT ++ Sbjct: 535 PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 591 Query: 401 -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 P + T+ L P+ T T E+P T + P P++ T E PTT Sbjct: 592 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 651 Query: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508 P P+TPK P T P TPK + + EPT TT Sbjct: 652 PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707 Query: 509 PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567 P T P P P T K PAP P P P P+ +P PK T Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 766 Query: 568 KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611 K TS P+P E + TTP P KP P ++ P P T+ P Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 825 Query: 612 FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663 SP S EL + T + + S +EP TTK P T+ TT A R T Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885 Query: 664 VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723 T+ P + K+ + + +T T + P + T + L P Sbjct: 886 TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 942 Query: 724 NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783 T K ITT + + P T P +R A+ + + T Sbjct: 943 KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 987 Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843 PT P PR + P + S + R EA T P Q P + Sbjct: 988 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 1045 Query: 844 LTVV 847 L V Sbjct: 1046 LVEV 1049 Score = 57.0 bits (136), Expect = 9e-08 Identities = 116/509 (22%), Positives = 179/509 (35%), Gaps = 63/509 (12%) Query: 449 TSPEMQPTTPAPQQTT-SIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTP 507 TSP P P + +I ST KR P+P P + K ++ + IT + S S ++ Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKP-PNKKKTKKVIESEEITEEHSVSENQESSSS 128 Query: 508 APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567 + + +++ KI S + K+ K K + + R + +P PK P V Sbjct: 129 SSSSSSSSTIR-KIKSSKNSAANRELQKKL-----KVKDNKKNRTKK-KPTPKPPV-VDE 180 Query: 568 KPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT 627 + + TTP + +VS S P T P I+P PS Sbjct: 181 AGSGLDNGDFKVTTPDTSTT-----QHNKVSTS---PKITTAKP----INPRPSLPPNSD 228 Query: 628 TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPGVKQAP 682 T +ET + + T + TT K T + TT T + + P K Sbjct: 229 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 288 Query: 683 RPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT 742 +P+ T K P P PT P+ P + T K + I S P T Sbjct: 289 KPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAP-T 335 Query: 743 TP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRF 798 TP P + PT TP E T K+P P + +E T +PT P+ Sbjct: 336 TPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393 Query: 799 KGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVVTVEGC 852 P P + +P + + PKE A T+ A + P+ P Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 453 Query: 853 PSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQV 911 P ++P T E ++E + K + T +T + P T+ Sbjct: 454 P-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506 Query: 912 KPKNPLGEGPVSNTVAFSTESADPRVSEP 940 PK P P + T +P + P Sbjct: 507 TPKEP---SPTTTKEPAPTTPKEPAPTTP 532 Score = 50.4 bits (119), Expect = 9e-06 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%) Query: 291 TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347 T K PA+ E++ K + + + P + P++ K +A T T E+ +T+ Sbjct: 859 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 918 Query: 348 PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407 T+++ D + + + + + P K++ K + T ++ + P + +P+ Sbjct: 919 VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 969 Query: 408 TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459 AT+ + P K ++ ++P +T P P V P+K+ T PE+ PT+ Sbjct: 970 -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 1027 Query: 460 PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519 + + P + P K P+ + G A G+T + L+P Sbjct: 1028 AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 1070 Query: 520 KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558 + PEVT P PR P + P S I +PV Sbjct: 1071 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1110 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 113 bits (282), Expect = 1e-24 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374 P S P + TV ET + + TT++ + D E T ++ E I T+ Sbjct: 260 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319 Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420 ++ SKVL T + + +PTT EP + T T+ + + P Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379 Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472 + + T + T P ++ T E PTT PAP T S P+TPK Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439 Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518 +P P K T+ TP K P PT PA P T Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499 Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568 P P P T TK PAP T AP K P P ++ P PK P T K Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 558 Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625 +P E + TTP P +P P + EPAP T + P P +P+ +E Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617 Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679 TT ++ +T E P T + P T ELA TT T P + P Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 677 Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739 + P P+ P P P+ T P P KP + Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 734 Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792 P TT ST P PT TP T K+P P + +E T ++PT +P Sbjct: 735 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 792 Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839 L KGP KP +P + ++ PKE A + T+P Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850 Query: 840 PPTNLTVVT 848 PPT V T Sbjct: 851 PPTTSEVST 859 Score = 92.0 bits (227), Expect = 3e-18 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%) Query: 290 TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345 TT K PA + + + A T + P K P + P TP+ T P+ Sbjct: 517 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 575 Query: 346 TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400 PTT + E +++KP PT E + +TA T +PTT ++ Sbjct: 576 PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 632 Query: 401 -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 P + T+ L P+ T T E+P T + P P++ T E PTT Sbjct: 633 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 692 Query: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508 P P+TPK P T P TPK + + EPT TT Sbjct: 693 PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748 Query: 509 PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567 P T P P P T K PAP P P P P+ +P PK T Sbjct: 749 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 807 Query: 568 KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611 K TS P+P E + TTP P KP P ++ P P T+ P Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 866 Query: 612 FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663 SP S EL + T + + S +EP TTK P T+ TT A R T Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926 Query: 664 VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723 T+ P + K+ + + +T T + P + T + L P Sbjct: 927 TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 983 Query: 724 NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783 T K ITT + + P T P +R A+ + + T Sbjct: 984 KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 1028 Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843 PT P PR + P + S + R EA T P Q P + Sbjct: 1029 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 1086 Query: 844 LTVV 847 L V Sbjct: 1087 LVEV 1090 Score = 57.0 bits (136), Expect = 9e-08 Identities = 116/509 (22%), Positives = 179/509 (35%), Gaps = 63/509 (12%) Query: 449 TSPEMQPTTPAPQQTT-SIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTP 507 TSP P P + +I ST KR P+P P + K ++ + IT + S S ++ Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKP-PNKKKTKKVIESEEITEEHSVSENQESSSS 169 Query: 508 APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567 + + +++ KI S + K+ K K + + R + +P PK P V Sbjct: 170 SSSSSSSSTIR-KIKSSKNSAANRELQKKL-----KVKDNKKNRTKK-KPTPKPPV-VDE 221 Query: 568 KPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT 627 + + TTP + +VS S P T P I+P PS Sbjct: 222 AGSGLDNGDFKVTTPDTSTT-----QHNKVSTS---PKITTAKP----INPRPSLPPNSD 269 Query: 628 TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPGVKQAP 682 T +ET + + T + TT K T + TT T + + P K Sbjct: 270 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 329 Query: 683 RPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT 742 +P+ T K P P PT P+ P + T K + I S P T Sbjct: 330 KPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAP-T 376 Query: 743 TP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRF 798 TP P + PT TP E T K+P P + +E T +PT P+ Sbjct: 377 TPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434 Query: 799 KGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVVTVEGC 852 P P + +P + + PKE A T+ A + P+ P Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 494 Query: 853 PSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQV 911 P ++P T E ++E + K + T +T + P T+ Sbjct: 495 P-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547 Query: 912 KPKNPLGEGPVSNTVAFSTESADPRVSEP 940 PK P P + T +P + P Sbjct: 548 TPKEP---SPTTTKEPAPTTPKEPAPTTP 573 Score = 50.4 bits (119), Expect = 9e-06 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%) Query: 291 TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347 T K PA+ E++ K + + + P + P++ K +A T T E+ +T+ Sbjct: 900 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 959 Query: 348 PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407 T+++ D + + + + + P K++ K + T ++ + P + +P+ Sbjct: 960 VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 1010 Query: 408 TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459 AT+ + P K ++ ++P +T P P V P+K+ T PE+ PT+ Sbjct: 1011 -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 1068 Query: 460 PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519 + + P + P K P+ + G A G+T + L+P Sbjct: 1069 AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 1111 Query: 520 KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558 + PEVT P PR P + P S I +PV Sbjct: 1112 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1151 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 110 bits (276), Expect = 5e-24 Identities = 162/638 (25%), Positives = 229/638 (35%), Gaps = 97/638 (15%) Query: 295 PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTP-----ETVPRSTKPT 349 P F ++L Q +K+ S TP K + P+ VTP T+P PT Sbjct: 830 PVEASFLPENSLSFQGSKDSPAT--THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887 Query: 350 TSSALDVSETTLASSEKPWIVPTAKISEDS-KVLQPQTATYDVFSSPTTSDEPEISDSYT 408 S ++ P P ++ S K + A + +SP+ P + T Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT-PPAAT 946 Query: 409 ATSDRILDSIPPKTSRTLEQPR-ATLAPSETPFVPQKLEIFTSPEMQPTTPA--PQQTTS 465 S PK P+ A P+ TP P+ SP+ PT PA P Sbjct: 947 PPS--------PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998 Query: 466 IPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPK-IP 522 P+TP + P PP P + + A T PK + +P P T P+P + + PK P Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP-PAATPPSPKGSPAATPLPKGAP 1057 Query: 523 LSPEVTHTKP-----------APKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK- 570 +P T P AP PP PK P P+ P+P P PK Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP--PAATPPSPKG 1115 Query: 571 ----------------TSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIP 614 T PSP+ TP PK P + A +G P P Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175 Query: 615 MISP--------SPSQEELQTTLEETDQSTQEPFTTKIPR--TTELAKTTQAPHRFYTTV 664 +P +PS + TT T S + T P+ T A T +P T Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235 Query: 665 RPRTSDK-----PHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPP----------L 709 P+ + P G P P GA + +T P+ K G PP Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA--ATPPSLKGGLATPPHKGAPNPAVVT 1293 Query: 710 PPRP------THPRRKPLPPNNVTGKP-GSAGIISSGPITTPPLRSTPRPTGTPLERIET 762 PP P + P+ P PP P GS G TPP + P P GTP T Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353 Query: 763 DIKQ--PTVPASGEELENITDFSSSPTRETDPLGKPRF--KGPHVRYIQKPDNSPCSITD 818 + PT P+S E T +++P+ + P P +GP + + SP I Sbjct: 1354 PSSKGGPTTPSSKE---GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410 Query: 819 SVKRFPKEEATEGNATSPPQN--PPTNLTVVTVEGCPS 854 S K+ P T A +P + P +T V+++ P+ Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448 Score = 110 bits (275), Expect = 7e-24 Identities = 152/562 (27%), Positives = 205/562 (36%), Gaps = 84/562 (14%) Query: 316 LALPAESKTPEVEKISARPTT--------VTPETVPRSTKPTTSSALDVSETTLASSEKP 367 +++ ++K P +K SA P T V+P V S P S + S+ + A++ P Sbjct: 799 VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP--VEASFLPENSLSFQGSKDSPATTHSP 856 Query: 368 WIVPTAKISEDSKVLQP-----------QTATYDVFSSPTTSDEPEISDSYTATSDRILD 416 P+ K + + P +T T V + P + P A + + Sbjct: 857 -TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915 Query: 417 SIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA--PQQTTSIPSTPKRRP 474 S P K RAT AP P P SP+ PT PA P P+TP + Sbjct: 916 SSPKKA-------RATPAPKGIPASP-------SPKGAPTPPAATPPSPKGGPATPSPKW 961 Query: 475 RPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPK-IPLSPEVTHTKPA 533 P PP P + G TP +P P TP K + PK P P VT P+ Sbjct: 962 APTPPAATPP-SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT--PPS 1018 Query: 534 PKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK--------TSPSPEVSYTTPAPK 585 PK +P A P PK + P T P PK T PK T PSP+ TP+ K Sbjct: 1019 PKGSPAATPFPKGASTPPAA-TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077 Query: 586 DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645 P P + PA +G P P +P + L T + +T P T P Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT--PAAT--P 1133 Query: 646 RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTR 705 + + T P TT + P G P P GA + +T P+ K G Sbjct: 1134 PSPKGGLATPPPKGAPTT----PAATPPSPKGGLATPPPKGAPTTPA--ATPPSPKGGLA 1187 Query: 706 RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR----STPRPTGTPLERIE 761 P PT P P P P G ++ P TPP +TP P G P Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-PAATPPSPKGGLATPSPKGAPTTPAA 1246 Query: 762 TDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG-PHVRYIQKPDNSPCSITDSV 820 T PA+ T +++P L P KG P+ + P Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS---------- 1296 Query: 821 KRFPKEEATEGNATSPPQNPPT 842 PK G ATSPP+ PT Sbjct: 1297 ---PKG----GPATSPPKGAPT 1311 Score = 97.1 bits (240), Expect = 8e-20 Identities = 149/566 (26%), Positives = 191/566 (33%), Gaps = 76/566 (13%) Query: 325 PEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLAS--SEKPWIVPTAKISEDSKVL 382 PE+ K + +P P T P T +S T+ + + P PT + Sbjct: 728 PEIPK-----SVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATAS 782 Query: 383 QPQTATY--------DVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434 T TY V SP T P S + P L P ++ Sbjct: 783 SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS----------AGPDTPIGNLSSP---VS 829 Query: 435 PSETPFVPQKLEIFTSPEMQP-TTPAPQQTTSIPSTPKRRPRPK---PPRTKPERTTSAG 490 P E F+P+ F + P TT +P P +PK P P P K Sbjct: 830 PVEASFLPENSLSFQGSKDSPATTHSPT-----PPSPKGAPTPSAVTPLSPKGVTLPPKE 884 Query: 491 TITPKISKSPEPTW--TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP 548 T TP + P P TPAP + +S+ SP+ PAPK P A P PK +P Sbjct: 885 TPTPSVVNLPFPKEGPATPAPKQAPALSMTSS---SPKKARATPAPKGIP-ASPSPKGAP 940 Query: 549 RPRI-----PQTQPVPKVPQRVTAKPK-TSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEP 602 P P+ P P+ P T PSP+ TP+PK P P + P Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000 Query: 603 APLETRGIPFIPMIS-PSPSQEELQTTLEE---TDQSTQEPFTTKIPRTTELAK---TTQ 655 A +G P P ++ PSP T + T + P P T L K TT Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060 Query: 656 APHRFYTTVRPRT-SDKPHIRPGVKQAPRPSGADRNVSVD-------STHPTKKPGTRRP 707 A P T S K P P P G S +T P+ K G P Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120 Query: 708 PLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPL----RSTPRPTGTPLERIETD 763 P PT P P P P G ++ P TPP +TP P G P T Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLATPPPKGAPTTPAATP 1179 Query: 764 IKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG-PHVRYIQKPDNSPCSITDSVKR 822 A+ T +++P L P KG P P T S K Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239 Query: 823 FPKEEATE------GNATSPPQNPPT 842 P A G AT PP+ PT Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPT 1265 Score = 87.4 bits (215), Expect = 6e-17 Identities = 142/583 (24%), Positives = 206/583 (35%), Gaps = 127/583 (21%) Query: 331 SARPTTVTPETVPRSTK-----------PTTSSALDVSETTLASSEKPWIVPTAKISED- 378 S + TP P S K PTT +A S ++ P PT + Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249 Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYT------ATSDRILDSIPPKTSRTLEQPR-A 431 S P T +P + P + A + ++ PK P+ A Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309 Query: 432 TLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPS-TPKRRPRPKPPRTKPERTTSA- 489 P+ TP SP+ P TP P+ + P+ TP P PK T P T S+ Sbjct: 1310 PTPPAATP---------PSPKGSPGTPPPKGAPTPPAVTP---PSPKGTPTLPATTPSSK 1357 Query: 490 -GTITPKISKSPEPTWTTPA-PGKTQFISLKPK-----------------IPLSPEVTHT 530 G TP + P P TP+ G PK IPLSP+ Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417 Query: 531 KPAPKQTPRAPPKPKTSPRPRIP---QTQPVPKVPQRVTAKPKTSPSPEV-SYTTPAPKD 586 P ++ P K +P P + P P+ A P + P + + T P+PK+ Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477 Query: 587 VLLPHK----PYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT 642 P + P+ + + PAP+ G P +P + PS +E + T S ++P Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPM---GAPTLPAVIPSSPKE-----VPATPSSRRDPIA- 1528 Query: 643 KIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIR-----PGVKQAPRPSGADRNVSVDSTH 697 P T L+K T A + P P + P K+AP + S + Sbjct: 1529 --PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586 Query: 698 PTKKPGTRRPP---LPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPL----RSTP 750 P+ G P +PP T P K P + P TPP +TP Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAP---------------TPPAVTPPSPEKGPATP 1631 Query: 751 RPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGK---------PRFKGP 801 P GTP P P+S + D +SP T +G P KGP Sbjct: 1632 APKGTP-------TSPPVTPSS------LKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678 Query: 802 ----HVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840 V P+++P IT ++ P + + +ATSPP P Sbjct: 1679 TALKEVLVAPAPESTPI-ITAPTRKGP--QTKKSSATSPPICP 1718 Score = 84.0 bits (206), Expect = 7e-16 Identities = 117/483 (24%), Positives = 173/483 (35%), Gaps = 54/483 (11%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P+ + P + PT+ P +P S P + A V+ A+ K + P Sbjct: 1387 PSPKRGPAIPSPKGDPTS--PAVIPLS--PKKAPATPVTREGAATPSKGDLTP------- 1435 Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438 P + +P TS + ++ D L ++ P + + P+ S Sbjct: 1436 -----PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS- 1489 Query: 439 PFVPQKLEIFTSPEMQPTTPA--PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI 496 P+K +P PT PA P +P+TP R P P + T+ PK Sbjct: 1490 ---PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546 Query: 497 SKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPR---IP 553 + P P T P+P KT I + P +P P TP K +P P+ IP Sbjct: 1547 ALIP-PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY---KGAPSPKELLIP 1602 Query: 554 QTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYP---EVSQSEPAPLETRGI 610 P + T T PSPE TPAPK P + S + PA + + Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662 Query: 611 PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD 670 +P S ++ T L+E + T I T T+ + P S Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722 Query: 671 KPHIR-PGVKQAPRPSGADRNVSVDSTHPTK-KPGTRRPPLPPRPTHPRRKPLPP----- 723 K + P AP P V DS+ K K + P P P P K P Sbjct: 1723 KNGSKGPLSTVAPAPL---LPVQKDSSKTAKGKDASHSPKGPLAP--PESKASTPLTAAA 1777 Query: 724 -NNVTGKPGSAGIISS-GPITTPPLRSTPRPTGTPLER--------IETDIKQPTVPASG 773 V KP SA + ++ P + PL +P PT P ++ + +P PA Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837 Query: 774 EEL 776 +EL Sbjct: 1838 DEL 1840 Score = 66.6 bits (161), Expect = 1e-10 Identities = 110/475 (23%), Positives = 167/475 (35%), Gaps = 81/475 (17%) Query: 236 DHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLP 295 D T+PA P KQV + + K + +P AP+G L +IP + P Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP--APMGAPTLP-AVIPSSPKEVPATP 1520 Query: 296 ASLMFEI-------SDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKP 348 +S I S LA E L PA + P +K A PT P S + Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT-VPSPKKTPAIPTPKEAPATPSSKEA 1579 Query: 349 TTSSALDVSETTLASSEKPWIVPTAKISEDSK-------VLQPQTATYDVFSSPT-TSDE 400 ++ A+ S A S K ++P A S K V P +P T Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS 1639 Query: 401 PEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAP 460 P ++ S S S+ K T+ Q L + P +++ + +PE P AP Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699 Query: 461 QQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPK 520 + K P+TK TS P I P+P+ + G ++ P Sbjct: 1700 TR--------------KGPQTKKSSATS-----PPI--CPDPSAKNGSKGPLSTVAPAPL 1738 Query: 521 IPLSPEVTHT------KPAPKQTPRAPPKPKTS------------PRPRIPQTQPVPKVP 562 +P+ + + T +PK P APP+ K S P+P P P Sbjct: 1739 LPVQKDSSKTAKGKDASHSPK-GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797 Query: 563 QRVTAKPKTSPS--PEVSYTTPAPKDVL-LPHKPYPEVSQSEPAPL-----ETRGIPF-- 612 + P P+ P+ + +P VL P KP + E PL + G+PF Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857 Query: 613 ------------IPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ 655 IP+ +PS Q + +S + ++ TTQ Sbjct: 1858 VLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQ 1912 Score = 48.1 bits (113), Expect = 4e-05 Identities = 88/422 (20%), Positives = 150/422 (35%), Gaps = 44/422 (10%) Query: 340 ETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSD 399 ETVP + + + + ++S+ + TA + + L P + + ++ Sbjct: 7 ETVPATEQELPQPQAETAVLPMSSA----LSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62 Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459 + S + + L+ P++S P T AP F+P + P + P A Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGT-APEAPTFLPNLI----GPPISPAALA 117 Query: 460 ---PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFIS 516 P ++ TP P + P + SP P+ G +S Sbjct: 118 LASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP-PSVAVAESGSVITLS 176 Query: 517 L-----KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKT 571 +PK L+ + P PK TP P T P + P+ + V + P+T Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVT---PMASIQSGVASLPQT 233 Query: 572 SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631 +P+ ++ +P KD + +S P L +G P P + S S + L Sbjct: 234 TPTTTLAIASPQVKDTTISSVL---ISPQNPGSLSLKG-PVSPPAALSLSTQSLPVVT-- 287 Query: 632 TDQSTQEPFTTK---IPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGAD 688 + Q T P T I + LA Q+ + +T P VK Sbjct: 288 SSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG-QTGPSALSDPTVK--------- 337 Query: 689 RNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRS 748 +SVD + ++R +PP P+ R + P V P A + GP T + Sbjct: 338 -TISVDHSSTGASYPSQRSVIPPLPS---RNEVVPATVAAFPVVAPSVDKGPSTISSITC 393 Query: 749 TP 750 +P Sbjct: 394 SP 395 Score = 47.8 bits (112), Expect = 6e-05 Identities = 133/607 (21%), Positives = 192/607 (31%), Gaps = 119/607 (19%) Query: 319 PAESKTPE-VEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISE 377 P+ K P + I+ P+ S PTTS L S +P + + Sbjct: 379 PSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGT 438 Query: 378 DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSE 437 V+ T + ++PTT+ E S +S I + P + + P A PS Sbjct: 439 TPLVV---TNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST 495 Query: 438 TPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRR-PRPKPPRTKPERTTSAG------ 490 V L I SP + P P+ ++PS+ + P K +T P A Sbjct: 496 Q--VATTLRIPVSPPL----PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549 Query: 491 --------TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTK-----PAP--- 534 T+ P + +P+ +P+ Q S P+IPLSPE T K P P Sbjct: 550 GLTTKKDPTVLPLVQAAPK---NSPS---FQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603 Query: 535 --------------------------------------KQTPRAPPKPKTSPRPRIPQT- 555 T A P P P T Sbjct: 604 PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA 663 Query: 556 --------QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET 607 P + V+ PK P E + TT + P Q+ APL T Sbjct: 664 KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723 Query: 608 RGI-PFIPMISPSPSQEELQTTLEETDQSTQEPFTTK---IPRTTELAKTTQAPHRFYT- 662 + P IP PSPS T P T K I T+ LA +P T Sbjct: 724 LVLAPEIPKSVPSPSLPPAGT----------PPGTKKVDGISHTSALAPVASSPKECPTE 773 Query: 663 -TVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP----PRPTHPR 717 + T+ + +P P G +VS + P K G+ P P P P Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGV--SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831 Query: 718 RKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELE 777 P N GS ++ TPP +P+ TP K T+P Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPP---SPKGAPTPSAVTPLSPKGVTLPPKETPTP 888 Query: 778 NITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP--CSITDSVKRFPKEEATEGNATS 835 ++ + P K + +SP T + K P + +G T Sbjct: 889 SVVNLPFPKEGPATPAPK------QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942 Query: 836 PPQNPPT 842 P PP+ Sbjct: 943 PAATPPS 949 >gi|16554449 zonadhesin isoform 3 [Homo sapiens] Length = 2812 Score = 109 bits (272), Expect = 2e-23 Identities = 143/515 (27%), Positives = 208/515 (40%), Gaps = 77/515 (14%) Query: 334 PTTVTPETVPRSTKPTT--SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDV 391 P V PE P S +T S ++E S++KP T I + S + T + Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKP----TVSIEKPSVTTEKPTVPKEK 590 Query: 392 FSSPTTSDEPEIS-DSYTATSDRILDSIP------PKTSRTLEQPRATLAPSETPFVPQK 444 + PT ++P IS + T S++ ++P P T+ + T+ PSE P +P + Sbjct: 591 PTIPT--EKPTISTEKPTIPSEK--PNMPSEKPTIPSEKPTILTEKPTI-PSEKPTIPSE 645 Query: 445 -----LEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS 499 E T P +PTTP + TTS+ +P P KP T TI+ + Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME---- 701 Query: 500 PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT-SPRPRIPQTQPV 558 E +T P ++ P+ P P T P K T +P KP T + +P IP +P Sbjct: 702 -ETIISTEKP------TISPEKPTIPTEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPT 753 Query: 559 --PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP-----YPEVSQSEP-APLETRGI 610 P+ P T KP SP T P K + KP P +S EP P E I Sbjct: 754 ISPEKPTTPTEKPTISPE---KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTI 810 Query: 611 ----PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666 P IPM P+ EE T++EET ST E T + + T + P T +P Sbjct: 811 STEKPSIPMEKPTLPTEETTTSVEETTIST-EKLTIPMEKPTISTEKPTIP-----TEKP 864 Query: 667 RTSDKPHIRPGVK-----QAPRPSGADRNVSVDS-THPTKKPGTRRPPLPPRPTHPRRKP 720 S + P K + P + +S + T PT+KP P +PT KP Sbjct: 865 TISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTIS----PEKPTISTEKP 920 Query: 721 LPPNNVTGKPGSAGIISSGPITTPPLRST--PRPTGTPLERIETDIKQPTVPASGEELEN 778 P P IS+ +T P + T P P E+ ++PT+P E Sbjct: 921 TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT-----EK 975 Query: 779 ITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813 +T + PT T+ KP + ++ P SP Sbjct: 976 LTIPTEKPTIPTE---KPTIPTEKLTALRPPHPSP 1007 >gi|27881494 zonadhesin isoform 6 [Homo sapiens] Length = 2721 Score = 109 bits (272), Expect = 2e-23 Identities = 143/515 (27%), Positives = 208/515 (40%), Gaps = 77/515 (14%) Query: 334 PTTVTPETVPRSTKPTT--SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDV 391 P V PE P S +T S ++E S++KP T I + S + T + Sbjct: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKP----TVSIEKPSVTTEKPTVPKEK 590 Query: 392 FSSPTTSDEPEIS-DSYTATSDRILDSIP------PKTSRTLEQPRATLAPSETPFVPQK 444 + PT ++P IS + T S++ ++P P T+ + T+ PSE P +P + Sbjct: 591 PTIPT--EKPTISTEKPTIPSEK--PNMPSEKPTIPSEKPTILTEKPTI-PSEKPTIPSE 645 Query: 445 -----LEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS 499 E T P +PTTP + TTS+ +P P KP T TI+ + Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME---- 701 Query: 500 PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT-SPRPRIPQTQPV 558 E +T P ++ P+ P P T P K T +P KP T + +P IP +P Sbjct: 702 -ETIISTEKP------TISPEKPTIPTEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPT 753 Query: 559 --PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP-----YPEVSQSEP-APLETRGI 610 P+ P T KP SP T P K + KP P +S EP P E I Sbjct: 754 ISPEKPTTPTEKPTISPE---KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTI 810 Query: 611 ----PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666 P IPM P+ EE T++EET ST E T + + T + P T +P Sbjct: 811 STEKPSIPMEKPTLPTEETTTSVEETTIST-EKLTIPMEKPTISTEKPTIP-----TEKP 864 Query: 667 RTSDKPHIRPGVK-----QAPRPSGADRNVSVDS-THPTKKPGTRRPPLPPRPTHPRRKP 720 S + P K + P + +S + T PT+KP P +PT KP Sbjct: 865 TISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTIS----PEKPTISTEKP 920 Query: 721 LPPNNVTGKPGSAGIISSGPITTPPLRST--PRPTGTPLERIETDIKQPTVPASGEELEN 778 P P IS+ +T P + T P P E+ ++PT+P E Sbjct: 921 TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT-----EK 975 Query: 779 ITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813 +T + PT T+ KP + ++ P SP Sbjct: 976 LTIPTEKPTIPTE---KPTIPTEKLTALRPPHPSP 1007 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 102 bits (254), Expect = 2e-21 Identities = 139/548 (25%), Positives = 196/548 (35%), Gaps = 75/548 (13%) Query: 315 TLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAK 374 T P T V + P PE P T ++ S AS P A Sbjct: 966 TTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPG---PAL 1022 Query: 375 ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRIL-DSIPPKTSRTLEQPRATL 433 S+ S+ L P +A +S TSD P+ S + R D I L P +++ Sbjct: 1023 TSDSSRELTPHSA----LTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSV 1078 Query: 434 APSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT 493 P+ TP P P P++ TS PSTP + +++ Sbjct: 1079 VPALTP----------EPSPTPLPTLPKELTSDPSTP----------------SEVTSLS 1112 Query: 494 PKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIP 553 P + PE TTP T + S + SP+ P+P P P P +P P I Sbjct: 1113 PTSEQVPESD-TTPDLDTTPYSSTVSEYSRSPD-----PSPSPHPTTTPDPTMAPDP-IT 1165 Query: 554 QTQPVPKVPQRVTAKPKTSPSPE-VSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF 612 P T P T+P P ++++T P P +P+ ++ S P Sbjct: 1166 TLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTP-QPFTTITHSTMIP-------- 1216 Query: 613 IPMISPSP--SQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD 670 P +P P + + T T T P T I +T + T P F TT++P T Sbjct: 1217 DPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPF-TTMQPTTMP 1275 Query: 671 KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP---------PRPTHPRRKPL 721 P P P P+ + + HPT P P P P PT P Sbjct: 1276 HPTTTPHPTTTPHPTTTPHPTT--TPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSST 1333 Query: 722 PPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT---PLERIETDIKQPTVPASGEELEN 778 P P S G S P P ++ + P T P T + PT+ S LE+ Sbjct: 1334 PVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTS-QIPTLEPS-PALES 1391 Query: 779 ITDFSSSPTRETDPLGKPRFKGPHVR---YIQKPDNSPCSITD-SVKRFPKEEATEGNAT 834 SS+ T DPL FK P + P ++P S +D +V P T Sbjct: 1392 SPSRSSTAT-SMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLD 1450 Query: 835 SPPQNPPT 842 PP +P T Sbjct: 1451 HPPLDPLT 1458 Score = 68.6 bits (166), Expect = 3e-11 Identities = 87/330 (26%), Positives = 112/330 (33%), Gaps = 70/330 (21%) Query: 334 PTTVTPETVPRSTKPTTSSALDVSETT----LASSEKPWIVPTAKISEDSKVLQPQTATY 389 PTT P T P T T S+ + TT + I + +QP T + Sbjct: 1176 PTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPH 1235 Query: 390 DVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFT 449 PTT+ P T IP T T QP T+ P+ P Sbjct: 1236 STTPHPTTTPHPTTITHSTM--------IPDPT--TTPQPFTTMQPTTMPH--------- 1276 Query: 450 SPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509 TTP P T +TP P P T TT T TP + +P P TTP P Sbjct: 1277 ----PTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHP--TTPDP 1330 Query: 510 GKTQFI----------------SLKP--KIPLSPEVTHTKPAP----KQTPRAPPKPKTS 547 T I +L P K L P++T T PAP Q P P P Sbjct: 1331 SSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALE 1390 Query: 548 PRPRIPQTQPVPKVPQRVTAKPKTSPSPEV-----------SYTTPAPKDVLLP------ 590 P T KP S SP + S T +P +L P Sbjct: 1391 SSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLD 1450 Query: 591 HKPYPEVSQSEPAPLETRGIPFIPMISPSP 620 H P ++ P P ++ G P P ++P+P Sbjct: 1451 HPPLDPLTLG-PTPGQSPG-PHGPCVAPTP 1478 Score = 60.1 bits (144), Expect = 1e-08 Identities = 89/378 (23%), Positives = 126/378 (33%), Gaps = 85/378 (22%) Query: 484 ERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKI--PLSPEVTHTKPAPKQTPRAP 541 E T +AG + P + TT +PG + + P P P P T AP Sbjct: 950 EGTPTAGKLGPTLGAG-----TTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAP 1004 Query: 542 PKPKTSPRPRIPQTQPVPKV---------PQRVTAKPKTSPSPEVSYTTPAPKDVLLPHK 592 P P SP P P P + P TS +P+ S TP P + Sbjct: 1005 PTP--SPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPAS-----R 1057 Query: 593 PYPEVSQSEPA-PLETRGIPFIPMISPSPSQEELQTTLEE--TDQSTQEPFTTKIPRTTE 649 P++ + P L T +P ++P PS L T +E +D ST T+ P + + Sbjct: 1058 TNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQ 1117 Query: 650 LAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPL 709 + ++ P T S+ ++P PS S HPT P P + Sbjct: 1118 VPESDTTPDLDTTPYSSTVSE-------YSRSPDPS--------PSPHPTTTPD---PTM 1159 Query: 710 PPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTV 769 P P I + P TP +TP PT TP PT Sbjct: 1160 APDP---------------------ITTLNPTVTPHFPTTPHPTTTP---------HPT- 1188 Query: 770 PASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEAT 829 IT + P T P +P H I P +P T T Sbjct: 1189 --------TITHSTMIPDPTTTP--QPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTT 1238 Query: 830 EGNATSPPQNPPTNLTVV 847 T+P T+ T++ Sbjct: 1239 PHPTTTPHPTTITHSTMI 1256 Score = 57.8 bits (138), Expect = 5e-08 Identities = 80/321 (24%), Positives = 116/321 (36%), Gaps = 39/321 (12%) Query: 260 VTHKDSAKSPEKAPLGGVILVH-LIIPGLNETTVKLPASLMFEISDALKTQLAKNET--- 315 +TH P P + H +IP + TT P + M + T T Sbjct: 1190 ITHSTMIPDPTTTPQPFTTITHSTMIP--DPTTTPQPFTTMQPTTTPHSTTPHPTTTPHP 1247 Query: 316 LALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375 + + P+ TT+ P T+P T TT T ++ P P + Sbjct: 1248 TTITHSTMIPDPTTTPQPFTTMQPTTMPHPT--TTPHPTTTPHPT--TTPHPTTTPHPTM 1303 Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAP 435 + D T T D PTT+ P D +S ++ ++ TS E TLAP Sbjct: 1304 TPDPTTTPYPTTTPD----PTTTPHPTTPDP---SSTPVITTVSLPTSLGTELSSPTLAP 1356 Query: 436 SETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP- 494 + P + P++ T PAP +TS P P P + P R+++A ++ P Sbjct: 1357 TVKPSL--------HPQLTFTAPAPHTSTS--QIPTLEPSPAL-ESSPSRSSTATSMDPL 1405 Query: 495 -----KISKSPEPTWTTP---APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT 546 K +S P T P P +++ P LSP P P P Sbjct: 1406 STEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQ 1465 Query: 547 SPRPRIPQTQPVPKVPQRVTA 567 SP P P P P P RV A Sbjct: 1466 SPGPHGPCVAPTP--PVRVMA 1484 Score = 38.5 bits (88), Expect = 0.034 Identities = 44/190 (23%), Positives = 67/190 (35%), Gaps = 29/190 (15%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASS-----EKPWIVPTA 373 P + TP+ TT P T P T P SS ++ +L +S P + PT Sbjct: 1299 PHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTV 1358 Query: 374 KISEDSKVL----QPQTATYDV--------------FSSPTTSDEPEISDSYTATSDRIL 415 K S ++ P T+T + SS TS +P ++ + + Sbjct: 1359 KPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSP 1418 Query: 416 DSIPPKT------SRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPST 469 + PP T S P L+P+ P L+ T +P P P+ Sbjct: 1419 NLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTP 1478 Query: 470 PKRRPRPKPP 479 P R +PP Sbjct: 1479 PVRVMACEPP 1488 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 95.5 bits (236), Expect = 2e-19 Identities = 129/514 (25%), Positives = 183/514 (35%), Gaps = 62/514 (12%) Query: 314 ETLALPAESKTPEVEKISARP----TTVTPETVPRSTKPTTSSALDVSET-----TLASS 364 E + P T E + P TTVTP P ST+ TT + + + T T + Sbjct: 1295 ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGT 1354 Query: 365 EKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSR 424 + P P + + P T T ++P T+ ++ + T T + S P T+ Sbjct: 1355 QTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTSTPITTTT 1412 Query: 425 TLEQ---PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRT 481 T+ P T P+ TP +P PT T+I +T P P P T Sbjct: 1413 TVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469 Query: 482 KPERTTSAGTITPKISKSPEPTWT-TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPR 539 + TT T T ++ +P PT T TP P I + VT T P QTP Sbjct: 1470 QTPTTTPI-TTTTTVTPTPTPTGTQTPTP---------TAITTTTTVTPTPTPTGTQTPT 1519 Query: 540 APPKPKT---SPRPRIPQTQPVPKVPQRVTAKPKTSPSP---EVSYTTPAPKDVLLPHKP 593 + P T +P P TQ P T +P+P + TTP + P Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579 Query: 594 YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--TLEETDQSTQEPFTTKIP-----R 646 P +Q+ L T P +P+ ++ T T T +T P T+ P Sbjct: 1580 TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIS 1639 Query: 647 TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706 TT T P T TS P I P P + S ++ P + T Sbjct: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAP-IAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 1698 Query: 707 PPLPP----RPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIET 762 LPP T P P P +G G +PP +T P GTP T Sbjct: 1699 STLPPAIEMTSTAPPSTPTAPTTTSG----------GHTLSPPPSTTTSPPGTPTRGTTT 1748 Query: 763 DIKQPTVPASGEELENITDFSSSPTRETDPLGKP 796 P++ + T +S+ T PL P Sbjct: 1749 GSSSAPTPSTVQ-----TTTTSAWTPTPTPLSTP 1777 Score = 83.6 bits (205), Expect = 9e-16 Identities = 140/560 (25%), Positives = 197/560 (35%), Gaps = 83/560 (14%) Query: 335 TTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED---SKVLQPQTATYD- 390 TT+T T P + TT++ S T L+++ K + + I+ED S T+D Sbjct: 1170 TTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG 1229 Query: 391 VFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETP----FVP---- 442 V +P + + D + + L+ + K + + +E +P Sbjct: 1230 VCGAPEDIECRSVKDPHLS-----LEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFC 1284 Query: 443 -------QKLEIFTSPEMQPTTPAPQQT-TSIPSTPKRRPRPKPPRTK---PERTTSAGT 491 Q E T P TT T T I +T P P P T+ P T+ T Sbjct: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344 Query: 492 ITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPRAPPKPKT---S 547 +TP TP P TQ + P I + VT T P QTP P T + Sbjct: 1345 VTP-----------TPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1392 Query: 548 PRPRIPQTQPVPKVPQRVTAKPKTSPSP---EVSYTTPAPKDVLLPHKPYPEVSQSEPAP 604 P P TQ P T +P+P + TTP + P P +Q+ P P Sbjct: 1393 PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQA-PTP 1451 Query: 605 LETRGIPFIPMISPSPSQEELQT------------TLEETDQSTQEPFTTKIPRTTELAK 652 I ++P+P+ QT T T TQ P T I TT + Sbjct: 1452 ---TAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTP 1508 Query: 653 T-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKP-GTRR 706 T TQ P T + T+ P P Q P P+ +V PT P GT+ Sbjct: 1509 TPTPTGTQTPTS--TPITTTTTVTPTPTPTGTQTPTPTPISTTTTVT---PTPTPTGTQT 1563 Query: 707 PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPLERIETDIK 765 P P T P P T P + I ++ +T TP ST T TP+ T Sbjct: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA 1623 Query: 766 QPTVPASGE----ELENITDFSSSPTRETDPLGKPRFKG----PHVRYIQKPDNSPCSIT 817 PT + + T + +PT T G P + P S T Sbjct: 1624 TPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQT 1683 Query: 818 DSVKRFPKEEATEGNATSPP 837 P E+T +T PP Sbjct: 1684 SRSTSSPLTESTTLLSTLPP 1703 Score = 68.2 bits (165), Expect = 4e-11 Identities = 92/360 (25%), Positives = 127/360 (35%), Gaps = 42/360 (11%) Query: 311 AKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIV 370 A T + TP + T TP T + PT + + T A + + Sbjct: 1448 APTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT 1507 Query: 371 PT-AKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQP 429 PT + P T T V +PT P + + T T ++ P + P Sbjct: 1508 PTPTPTGTQTPTSTPITTTTTVTPTPT----PTGTQTPTPTPISTTTTVTPTPT-----P 1558 Query: 430 RATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTK-----PE 484 T P+ TP +P PT T I +T P P P TK P Sbjct: 1559 TGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615 Query: 485 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAP---KQTPRAP 541 TT+ T TP + + PT + T + P + THT AP T P Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP 1675 Query: 542 PK---PKTSPRPRIPQTQPV-------PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH 591 P+ P+TS P T+ P + TA P T +P TT + L P Sbjct: 1676 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP----TTTSGGHTLSP- 1730 Query: 592 KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT-KIPRTTEL 650 P + + P TRG +P+PS +QTT T P +T I RTT L Sbjct: 1731 ---PPSTTTSPPGTPTRGTTTGSSSAPTPS--TVQTTTTSAWTPTPTPLSTPSIIRTTGL 1785 Score = 64.3 bits (155), Expect = 6e-10 Identities = 79/301 (26%), Positives = 115/301 (38%), Gaps = 65/301 (21%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLAS-----SEKPWIVPTA 373 P ++TP I+ TT+TP P STK TT + + + T A+ ++ P ++P Sbjct: 1581 PTGTQTPTTVLITTT-TTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP-- 1637 Query: 374 KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATL 433 IS + V T T PT + I++ TS+ +S P+TSR+ P T Sbjct: 1638 -ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE--LTTSNPPPESSTPQTSRSTSSP-LTE 1693 Query: 434 APSETPFVPQKLEIF-TSPEMQPTTPA-----------PQQTTSIPSTPKR-----RPRP 476 + + +P +E+ T+P PT P P TTS P TP R Sbjct: 1694 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 1753 Query: 477 KPPRTKPERTTSAGTITPKISKSPEPTWTTP-------------------APGKT----- 512 P T TTSA T TP +P TT APG+ Sbjct: 1754 PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGT 1813 Query: 513 -----QFISLKPKIPLS------PEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV 561 F++ L P P P ++ P KP ++P P T+P P+ Sbjct: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKP-PEC 1872 Query: 562 P 562 P Sbjct: 1873 P 1873 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 93.2 bits (230), Expect = 1e-18 Identities = 143/623 (22%), Positives = 218/623 (34%), Gaps = 100/623 (16%) Query: 284 IPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 343 +P + LPA+L S L T L LA P+ S P ++ + + P T + P Sbjct: 317 VPPPDNAATPLPATL--PPSPPLATPLP----LAPPSPSAPPSLQTLPSPPATPPSQAPP 370 Query: 344 RSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEI 403 T P + + P I ++ S P + T+ P + Sbjct: 371 SMTTPPMQAPPSLQTI-------PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423 Query: 404 SDSYTATSDRILDSIPPKTSRTLEQP-RATLAPSETPFVPQKLEIFTSPEMQ-------- 454 +++ L P +T +L P R P ++P + L + SP +Q Sbjct: 424 QATHS-----FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478 Query: 455 ----PTTPAPQQTTSIPSTPKRRPR-PKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509 P T P Q S S P+ P P T + P + ++P + TTP Sbjct: 479 PLSSPLTIHPLQALS--SLASHSPQAPLSSLIMPPLETQSSLAPPSL-QTPPASLTTPPL 535 Query: 510 GKTQFISLKP----KIPLSPEVTHTKPAPKQTP-RAPPKPKTSPRPRIPQT--QPVPKVP 562 ++ P PL+ T P P P +APP P T+P P P + P P+ P Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595 Query: 563 QRVTAKP-KTSPSPEVS-YTTP---APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMIS 617 + + P + PSP +S TP AP + LP P + P P P+ + Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP--------PLSPLAT 647 Query: 618 PSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPG 677 PSP Q PF+ + + A + P + P + Sbjct: 648 PSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702 Query: 678 VKQAPRPSGADRNVSVDSTHPTKKP-------------GTRRPPLPPRPTHPRRKP---- 720 Q P A +S +T P + P PP+ P T P R P Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA 762 Query: 721 LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780 PP V P ++ + P+ PP ++ P PL+ + P+ PAS Sbjct: 763 APPLQVPPSPPAS--LPMSPLAKPPPQAPPALATPPLQAL------PSPPAS---FPGQA 811 Query: 781 DFSSSPTRETDPLGKPRFKGPHV---RYIQKPDNSPCSITDSVKRFPKEEATEGNATSP- 836 FS S + PL P + P V +Q P + P S T R P + + + P Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871 Query: 837 --------PQNPPTNLTVVTVEG 851 P PP+ T+ G Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSG 894 Score = 66.6 bits (161), Expect = 1e-10 Identities = 126/547 (23%), Positives = 186/547 (34%), Gaps = 64/547 (11%) Query: 317 ALPAESKTPEVEKISARPTTVTPETVPRS--TKPTTSSALDVSETTLASSEKPWIVPTAK 374 A A + P E+ PE+ PR+ T+ +S+ + + AS P AK Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGER-APPAK 107 Query: 375 ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434 + V P A+ P IS T + ++ P +++ + R T Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSG 166 Query: 435 PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP 494 P TP P SP M + A +P P RP+PP P ++ S+ + Sbjct: 167 P--TPGTP-------SPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHS 216 Query: 495 KISKSPEPTWTTPAPGKTQFISLKP----KIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP 550 SP A G Q + + PLS + P+ + TPRAP P + P+P Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA-RSGPSARGTPRAPAHP-SQPKP 274 Query: 551 RIPQTQPVPKV-PQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609 + Q P+V P R A P P TP+P +P P P + Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA--RPVP--------PPDNAA 324 Query: 610 IPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTS 669 P + PSP L T L S P + + + +QAP P + Sbjct: 325 TPLPATLPPSPP---LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP--------PSMT 373 Query: 670 DKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGK 729 P P Q P + H P + PP P L T Sbjct: 374 TPPMQAPPSLQTIPP--------IQVPHSLTSPSLQAPPSP--------LALSSLQATTS 417 Query: 730 PGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRE 789 GS + ++ T R T +P T P + A L +S + Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP-LSLPASPPLQTSLSPA 476 Query: 790 TDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPP--QNPPTNLTVV 847 PL P P +SP + S+ P E + + +PP Q PP +LT Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS---SLAPPSLQTPPASLTTP 533 Query: 848 TVEGCPS 854 +E PS Sbjct: 534 PLENLPS 540 Score = 63.2 bits (152), Expect = 1e-09 Identities = 104/463 (22%), Positives = 150/463 (32%), Gaps = 83/463 (17%) Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEI--FTSPEMQPTTPAPQQTTSIPSTPKRRPRP 476 PP T L A A P + I T PE P T T R P Sbjct: 37 PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP----TRSAGTSSRNPAS 92 Query: 477 KPPRT-KPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPK 535 +PP + + ER A +P SP T PG L+ +S E T A Sbjct: 93 RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR----ISAEET---VARG 145 Query: 536 QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYP 595 + AP + S R + P P P A+ + EV PAP P P Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205 Query: 596 EVSQSEPAPLETRGIPFIPMISPSPSQEE-------LQTTLEETDQSTQEPFTTKIPRTT 648 S S + T PSP+ LQ + S+ P ++ Sbjct: 206 RKSVSSASEHSTT--------EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257 Query: 649 ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPP 708 T +AP +P+ +RP PR A P P + P Sbjct: 258 SARGTPRAPAH---PSQPKPKGLQALRPPQVTPPRKDAA----------PALGPLSSSPL 304 Query: 709 LPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITT------------PPLRSTPRPTGTP 756 P P+ + +P+PP + P A + S P+ T P L++ P P TP Sbjct: 305 ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364 Query: 757 LERIETDIKQPTVPASGEELENITDFS-----SSPTRETDP-------------LGKPRF 798 + + P + A L+ I +SP+ + P LG P Sbjct: 365 PSQAPPSMTTPPMQAP-PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423 Query: 799 KGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPP 841 + H P + S+T + A++PP +PP Sbjct: 424 QATHSFLTMSPRQTQASLTSPSR----------PASTPPDSPP 456 Score = 50.1 bits (118), Expect = 1e-05 Identities = 89/399 (22%), Positives = 132/399 (33%), Gaps = 59/399 (14%) Query: 475 RPKPPRTKPERTTSA---GTITPKISKSPEPTW-TTPAP----GKTQFISLKPKIPLSPE 526 R K RT +A G +TP+ SP P TPA G + KP + Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 527 VTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKD 586 + P+ PRA P R P ++P A + +P T+P P Sbjct: 65 IGGAT-IPESAPRAGPTRSAGTSSRNPASRP--------PASGRGERAPPAKNTSPGPVS 115 Query: 587 VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPR 646 P + P PL +G+ S EE + T+ + + R Sbjct: 116 -----SPGRASGTTRPGPLGQKGLRI--------SAEETVARGKATEAPKRSALSAGARR 162 Query: 647 TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRP--SGADRNVSVDSTHPTKKPGT 704 T R ++ RP PRP G ++VS S H T +P Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222 Query: 705 RRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDI 764 RR+P + +P S + SS + P RS P GTP R Sbjct: 223 AA----------RRRPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGTP--RAPAHP 269 Query: 765 KQPTVPASGEELENITDFSSSPTRE----------TDPLGKPRFKGPHVRYIQKPDNSPC 814 QP + L+ + +P R+ + PL P G R + PDN+ Sbjct: 270 SQP----KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325 Query: 815 SITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCP 853 + ++ P A P PP+ T+ + P Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 87.4 bits (215), Expect = 6e-17 Identities = 82/320 (25%), Positives = 132/320 (41%), Gaps = 22/320 (6%) Query: 417 SIPPKTSRTLEQPRATLA---PSETPF--VPQKLEIFTSPEMQPTTPAPQQT--TSIPST 469 S PP+ S T P A+ P E P +P+ L + E P +P P+++ + P + Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509 Query: 470 PKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSP--EV 527 P + P + PE + + + +S PE + +P ++ ++P SP E Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA 569 Query: 528 THTKPAPKQTPRAPPKPKTSPRPRIPQTQPV-PKVPQRVTAKPKT----SPSPEVSYTTP 582 + P P+++P +PP P+ SP P+ + P + + P SP PE S +P Sbjct: 570 SRLSPPPEESPMSPP-PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628 Query: 583 APKDVLLPHKPYPEVSQSEPAPLETR--GIPFIPMISPSPSQEELQTTLEETDQSTQEPF 640 P+D P P PE S P P +R +P + +SP P + L EE+ S P Sbjct: 629 PPED--SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS-PPPE 685 Query: 641 TTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700 +++ E + T+ P + P D P + P + + S P Sbjct: 686 ASRLSPPPEDSPTSPPPED--SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743 Query: 701 KPGTRRPPLPPRPTHPRRKP 720 P P L PRP P P Sbjct: 744 SPRPEEPHLSPRPEEPHLSP 763 Score = 65.9 bits (159), Expect = 2e-10 Identities = 134/581 (23%), Positives = 201/581 (34%), Gaps = 89/581 (15%) Query: 319 PAESKT---PEVEKISA----RPTTVTPETVPRSTKPTTS-SALDVSETTLAS-SEKPWI 369 P ES T PE ++S PT+ PE P S P S +L + E+ L E+P + Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734 Query: 370 VPTAKISEDSKVLQPQTATYDVFSSPTT------SDEPEISDSYTATSDRILDSIP--PK 421 P + + L P+ + P ++EP +S + L ++P P Sbjct: 735 CPRS----EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ---PEEPCLCAVPEEPH 787 Query: 422 TSRTLEQPRATLAPSETPFVPQKLEIFTSP--EMQPTTPAPQQTTSIPST--PKRRPRPK 477 S E P + P E PQ E SP E +P P+++ P + P PRP+ Sbjct: 788 LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847 Query: 478 PPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTH-------- 529 PE ++P+ K PE PAP + + LSP + Sbjct: 848 ESHLSPE--LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905 Query: 530 --TKPAPKQTPRAPP-KPKTSPRPRIPQTQPVPKVP-QRVTAKPKTSPSPEVSYTTPAPK 585 P P++ P +P +P SP+ P P P P A P SP E+ Y A Sbjct: 906 PPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKG 965 Query: 586 D-----------VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQ 634 D + P P PE + ++P P+ +P P P+ L L Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP---- 1021 Query: 635 STQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVD 694 P+ + L + + P P P + V P G VS + Sbjct: 1022 ----------PQCSPLLQHSLVPQ----NSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067 Query: 695 S------THPTKKPGTRRPPLPPRPTHPRRKPLPPNNV---TGKPGSAGIISSGPITTP- 744 + T +P P L P T P P+ + + P G T P Sbjct: 1068 AELHEMETEKVSEP--ECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPL 1125 Query: 745 ----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSP-TRETDPLGKPRFK 799 S P P TP + +++K V EEL +T P ++T G P + Sbjct: 1126 DGIDAPGSQPEPGQTP-GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEE 1184 Query: 800 GPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840 R P +D V + +A+ P P Sbjct: 1185 QEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEP 1225 Score = 57.4 bits (137), Expect = 7e-08 Identities = 82/374 (21%), Positives = 127/374 (33%), Gaps = 43/374 (11%) Query: 455 PTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP-GKTQ 513 PTTPA T++ KPP S G + K+ + P G Sbjct: 2129 PTTPAGLSTSADGFL-------KPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAP 2181 Query: 514 FISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSP 573 L+P+ P +P P+P P PP S RP Q P ++P Sbjct: 2182 AYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP 2241 Query: 574 SPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSP---SQEELQTTLE 630 P + P+ ++ +P P ++ P++SP P S++ L+ E Sbjct: 2242 DPFLKPRCPSLDNLAVPESPGVGGGKASE-----------PLLSPPPFGESRKALEVKKE 2290 Query: 631 ETDQSTQE------PFTTKIPRTTEL-AKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPR 683 E S+ F T L + P F + PR S PG+ P+ Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350 Query: 684 -PSGADRNVSVDSTHP-TKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPI 741 P A +HP +PG+ P P PR +P PP + P + + S P Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS--LPSDPF 2408 Query: 742 TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEEL--ENITDFSSSPTRETDPLGKPRFK 799 + P +P + + P S E +T SP + P +P+ + Sbjct: 2409 SRVP--------ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460 Query: 800 GPHVRYIQKPDNSP 813 P + P P Sbjct: 2461 DPFAPLHKPPRPQP 2474 Score = 50.8 bits (120), Expect = 7e-06 Identities = 105/457 (22%), Positives = 155/457 (33%), Gaps = 84/457 (18%) Query: 306 LKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSE 365 LK + + LA+P ++P V A ++P S K AL+V + L +S Sbjct: 2245 LKPRCPSLDNLAVP---ESPGVGGGKASEPLLSPPPFGESRK-----ALEVKKEELGASS 2296 Query: 366 KPWIVPTAKI----SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPK 421 + P S + + + T DVF +P T P+ Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT----------------------PR 2334 Query: 422 TSRTLEQ-PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR 480 S+ Q P L P E P + SP P P T + P PRP+PP Sbjct: 2335 ASQVEPQSPGLGLRPQEPP---PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP- 2390 Query: 481 TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA 540 PE + P S +P PA ++Q S P P P+P Sbjct: 2391 -PPESCCA----LPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445 Query: 541 PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600 P P + P R P + P KP PEV++ + L +P + Sbjct: 2446 SPDPYSRPPSR-----PQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPA 2500 Query: 601 EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660 PA +P S Q P + P T T +P RF Sbjct: 2501 GPAGELHAKVP-----------------------SGQPPNFVRSPGTGAFV-GTPSPMRF 2536 Query: 661 YTTVRPRTSDKPHIRPGVKQ--APRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRR 718 P+ +P ++P V Q P P G + + T KP + + HP Sbjct: 2537 ---TFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT--LGKPQSTNYTVATGNFHPSG 2591 Query: 719 KPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT 755 PL P+ +G G + +S P+ P + P P G+ Sbjct: 2592 SPLGPS--SGSTGESYGLS--PLRPPSVLPPPAPDGS 2624 Score = 45.8 bits (107), Expect = 2e-04 Identities = 97/406 (23%), Positives = 146/406 (35%), Gaps = 90/406 (22%) Query: 435 PSETPF-----VPQKLEIFTSPEMQPTTPAP----------------------QQTTSIP 467 PS+ PF P + T+P P P+P + T+ P Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231 Query: 468 STPKRRPRPKPPRTKPERTTSAGTITPKI-----SKSPEPTWTTPAPGKTQFISLKPKIP 522 TP+ +P P KP + P+ K+ EP + P G+++ K Sbjct: 2232 GTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEE 2291 Query: 523 L---SPEV--------------THTKPAPKQTP---RAPPKPKTSP-RPRIPQTQPVPKV 561 L SP TH +TP +AP P+ S P+ P P+ Sbjct: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351 Query: 562 PQRVTAKPKTSPS-PEV----SYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI 616 P A + PS P++ SYT P + L P +P P +S A L R +P P Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP-RPQPPPPESCCA-LPPRSLPSDP-F 2408 Query: 617 SPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRP 676 S P+ + Q+ S+Q P T + P + E + RF + P +P RP Sbjct: 2409 SRVPASPQSQS-------SSQSPLTPR-PLSAEAFCPSPVTPRFQS---PDPYSRPPSRP 2457 Query: 677 -------GVKQAPRPSGADRNVSVDS-THPTKKPGTRRPPLPPRPTHPRRKPLP---PNN 725 + + PRP + S H + G LP P +P P N Sbjct: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517 Query: 726 VTGKPGSAGIISSGPITTPPLRST-PRPTGTPLERIETDIKQPTVP 770 PG+ + T P+R T P+ G P ++ + QP +P Sbjct: 2518 FVRSPGTGAFVG----TPSPMRFTFPQAVGEP--SLKPPVPQPGLP 2557 Score = 45.1 bits (105), Expect = 4e-04 Identities = 69/326 (21%), Positives = 102/326 (31%), Gaps = 33/326 (10%) Query: 532 PAPKQTPRAPP---------KPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 582 P P TP P +PK + QP P + AKP ++ Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGG---HVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLE 431 Query: 583 APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT 642 AP + +P P PE S P P E+ SP P L EE S P Sbjct: 432 APLNEEMPLLPPPEESPLSPPPEES-------PTSPPPEASRLSPPPEELPASPL-PEAL 483 Query: 643 KIPRTTELAKTTQAPHRFYTTVRPRTS-----DKPHIRPGVKQAPRPSGADRNVSVDSTH 697 + R E + + P + P +S ++ + P + P P+ Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543 Query: 698 PTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPL 757 P P P PP P P + ++ P P++ PP S P Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPP------EESPMSPPPEESPMSPPPEAS 597 Query: 758 ERIETDIKQPTVPASGEELENITDFSS--SPTRETDPLGKPRFKGPHVRYIQKPDNSPCS 815 + P P E + +S SP E P+ P + P + SP Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657 Query: 816 ITDSVKRFPKEEATEGNATSPPQNPP 841 + + P+E P +PP Sbjct: 658 VVSRLSPPPEESPLSPPPEESPTSPP 683 Score = 40.0 bits (92), Expect = 0.012 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 382 LQPQTATYDVFSSPTTSDEPEISDSYTATSDRI----LDSIPPKTSRTLEQPRATLAPSE 437 L+ Q + + + EP SYT + L + PP+ P + LAPS Sbjct: 4869 LKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP---SPPPSPLAPSP 4925 Query: 438 -TPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPP 479 +P +E+ T P +P P+P S P + + +PR +PP Sbjct: 4926 ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968 Score = 34.7 bits (78), Expect = 0.50 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Query: 526 EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 585 +V P + P PP P +P P P T+P+ ++P A+P PSP ++P Sbjct: 4902 DVRQLSAPPPEEPSPPPSP-LAPSPASPPTEPLVELPTEPLAEPPV-PSPLPLASSPESA 4959 Query: 586 DVLLPHKPYPEVSQSEPAPLE 606 +P E S P L+ Sbjct: 4960 RPKPRARPPEEGEDSRPPRLK 4980 Score = 33.1 bits (74), Expect = 1.4 Identities = 94/394 (23%), Positives = 138/394 (35%), Gaps = 80/394 (20%) Query: 426 LEQPRATLAPSET--------PFVPQK-LEIFTSP------------EMQPTTPA-PQQT 463 L Q R L+P + P +P K L+ F+SP E PA + Sbjct: 3978 LNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEA 4037 Query: 464 TSIPSTPKRRPRPKPPRTKPER-TTSAGTITPKISKSPEPTWTTPAPG-KTQFISLKPKI 521 T PST + P T PE T G + P +S + P P + + L+P + Sbjct: 4038 TEGPST--HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPL 4095 Query: 522 PLSPEV-------------THTKPAPKQTPRAPPKPKTSPRPRIP-------QTQPVPKV 561 L + +H + + A P +P + TQ + Sbjct: 4096 RLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGP 4155 Query: 562 PQRVTAKP---KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAP---LETRGI----P 611 Q + +P T P P P P VL + P V + +G+ P Sbjct: 4156 QQPMLERPMQNNTGPQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP 4209 Query: 612 FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDK 671 + +SP Q++LQ L + Q Q + P E T +P + +P+ Sbjct: 4210 QLRHLSPQ-QQQQLQALLMQR-QLQQSQAVRQTPPYQEPGTQT-SPLQGLLGCQPQLGGF 4266 Query: 672 PHIRPGVKQ----APRPSGADRNVSVD---STHPTKKPGTRRPPLPPRPTHPRRKPLPPN 724 P + G Q PRP G R + ST P P PP P P P+R P+ Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP-PSSPQEPKRPSQLPS 4325 Query: 725 NVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLE 758 + P A + P T P TP+P G LE Sbjct: 4326 PSSQLPTEAQL----PPTHP---GTPKPQGPTLE 4352 Score = 32.7 bits (73), Expect = 1.9 Identities = 61/255 (23%), Positives = 89/255 (34%), Gaps = 31/255 (12%) Query: 532 PAPKQTPRAPPKP---KTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588 P P+ PR P P T P P P PQ +P PSP T A Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE-PKRPSQLPSPSSQLPTEAQLPPT 4339 Query: 589 LPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTT 648 P P P+ EP P SP+ +L TL +P + T Sbjct: 4340 HPGTPKPQGPTLEPPPGRV-----------SPAAAQLADTLFSKGLGPWDP-PDNLAETQ 4387 Query: 649 ELAKTTQAP---HRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTR 705 + +++ P + V P S + I+ ++ P GA + P PGT Sbjct: 4388 KPEQSSLVPGHLDQVNGQVVPEAS-QLSIKQEPREEPCALGAQSVKREANGEPIGAPGTS 4446 Query: 706 RPPLPPRPTHPR-----RKPLPPNNV---TGKPGSAGIIS--SGPITTPPLRSTPRPTGT 755 L P +K L NV TG+ GS G+ + +G I + + GT Sbjct: 4447 NHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGR-GSEGLRAEINGHIDSKLAGLEQKLQGT 4505 Query: 756 PLERIETDIKQPTVP 770 P + + ++P P Sbjct: 4506 PSNKEDAAARKPLTP 4520 Score = 32.3 bits (72), Expect = 2.5 Identities = 79/374 (21%), Positives = 126/374 (33%), Gaps = 64/374 (17%) Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQ------------PTTPAPQQTTSIPSTPKRRPRP 476 P ++L P+ P V QK+ +P + + A + T+ + S P Sbjct: 4622 PPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALP 4681 Query: 477 KPPRTKPER--------TTSAGTITPKISKSPEPTWTTPAPG---------KTQFISLKP 519 PP + E + S +I P + SPE AP + + +L P Sbjct: 4682 TPPHNQTEDVRMESDEDSDSPDSIVP--ASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739 Query: 520 KIPLSPEVT-----HTKPAPKQTPRAPPK-PKTSPRPRIPQTQPVPKVPQRVTAKPKTSP 573 IPL P + TKP P K P T+ V AK Sbjct: 4740 VIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799 Query: 574 SPEV----SYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629 V S P +VL P P + +EP E G P ++ L+ Sbjct: 4800 MVAVAELLSMKIPNSYEVLFPESPAR--AGTEPKKGEAEG--------PGGKEKGLEGKS 4849 Query: 630 EETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADR 689 +T + F +P T ++ + + P P + + + ++ Sbjct: 4850 PDTGPDWLKQFDAVLPGYTLKSQLD--------ILSLLKQESPAPEPPTQHSYTYNVSNL 4901 Query: 690 NVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLP--PNNVTGKPGSAGIISSGPITTPPLR 747 +V S P ++P PL P P P +PL P +P + S P+ + P Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP---PVPSPLPLASSPES 4958 Query: 748 STPRPTGTPLERIE 761 + P+P P E E Sbjct: 4959 ARPKPRARPPEEGE 4972 Score = 31.6 bits (70), Expect = 4.2 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 702 PGTRRPPLP-----PRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTP 756 PG + PL PRP P R P PP ++ P + + P ++P P +P Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326 Query: 757 LERIETDIKQP 767 ++ T+ + P Sbjct: 4327 SSQLPTEAQLP 4337 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 86.7 bits (213), Expect = 1e-16 Identities = 162/715 (22%), Positives = 245/715 (34%), Gaps = 74/715 (10%) Query: 249 PITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKT 308 P+T Q + T D P G + +P S M +S T Sbjct: 2368 PVTTYSQAGSSPTTADDTSMPTSTYSEG-----------STPLTSVPVSTMPVVSSEAST 2416 Query: 309 QLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKP---TTSSALDVSETTLASSE 365 + P + T + S+ PTT ++P S T +++ VS T + SSE Sbjct: 2417 HSTTPVDTSTPVTTST----EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSE 2472 Query: 366 KPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRT 425 + T + P T + + SSPTT+++ + S + +L SIP T+ Sbjct: 2473 AGTLSTTPVDTST-----PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPV 2527 Query: 426 LEQPRATLA----PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRT 481 +TL+ S +P V EI +S T P T S STP R P T Sbjct: 2528 ASPEASTLSTTPVDSNSPVV-TSTEISSSATSAEGTSMPTSTYSEGSTPL---RSMPVST 2583 Query: 482 KPERTTSAGTI--TPKISKSP--EPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQT 537 KP ++ A T+ TP + P T T+ +P + S+ P + T Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTM 2643 Query: 538 PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH--KPYP 595 P A + T + T+ + ++ P T+ + +TP + L + Sbjct: 2644 PVASSEASTLSTTPV-DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTT 2702 Query: 596 EVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ 655 ++ SE + L T + ++ S TT E T P P T+ L T Sbjct: 2703 LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLP 2762 Query: 656 APHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTH 715 +TV D P + + S+ PT T P P T Sbjct: 2763 VASSEASTVSTTAVD--------TSIPVTTSTEA-----SSSPTTAEVTSMPTSTPSETS 2809 Query: 716 PRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEE 775 +P N+ AG +S+ P+ T STP T T T + VP S Sbjct: 2810 TPLTSMPVNHTPVASSEAGTLSTTPVDT----STPVTTSTKASSSPTTAEGIVVPISTAS 2865 Query: 776 LENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNA-- 833 E T +S P T P P ++ +T S + EG + Sbjct: 2866 -EGSTLLTSIPVSTT-----PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMP 2919 Query: 834 TSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQ 893 S P T LT + V P V L+ T + + S + + T+ Sbjct: 2920 ISTPSEVSTPLTSILVSTVP--VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM 2977 Query: 894 TFSTV-ENLKPNTSYEFQVKP-----KNPLGEGP--VSNTVAFSTE-SADPRVSE 939 ST E P TS P + L P S V STE S+ P +E Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE 3032 Score = 81.3 bits (199), Expect = 5e-15 Identities = 182/780 (23%), Positives = 268/780 (34%), Gaps = 148/780 (18%) Query: 292 VKLPASLMFEISDALK------TQLAKNETLAL---PAESKTPEVEK--ISARPTTVTPE 340 + +P S E LK T +A +E L P +S +P V +S+ PT Sbjct: 1443 ISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1502 Query: 341 TVPRSTKPTTSSALD---VSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTT 397 ++ ST S+AL VS TT+ASSE + T ++ P T SSPTT Sbjct: 1503 SIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST-----PVTTYSQASSSPTT 1557 Query: 398 SDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 +D + S + L S+P T + TL S TP + K ++ S E +T Sbjct: 1558 ADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL--STTP-IDSKTQVTASTEASSST 1614 Query: 458 PAPQQT-------------TSIP--STPKRRPRPKPPRTKPERTTSAGTITPKISKSPEP 502 A + TSIP +TP P T P + S + ++S SP P Sbjct: 1615 TAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTP 1674 Query: 503 TWTTPAP------GKTQFISL----KPKIPLSPEVTHTKPAPKQTP-----RAPPKPKTS 547 T P G+T S+ P + T P TP A P TS Sbjct: 1675 AEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTS 1734 Query: 548 PRPRIPQTQPVPKVPQRVTAKPKTSP--SPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPL 605 +P + P + T+P S E S + P D P E + S P Sbjct: 1735 EGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEAT-SSPTTA 1793 Query: 606 ETRGIPFIPM---ISPSPSQEELQTTLEETDQST--QEPFTTKIPRTTELAKT------- 653 E IP + ++P S T + ++ ST P + P T A + Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1853 Query: 654 -----TQAPHR----------FYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV----D 694 T P TTV ++ P V P + A + S Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913 Query: 695 STHPTKKPGTRRPPL--------------------------PPRPTHPRRKPLPPN-NVT 727 S+ PT P RPPL P T+ + P + T Sbjct: 1914 SSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGT 1973 Query: 728 GKPGSAGIISSGPITTPP-------------LRSTPRPTGTPLERIETDIKQPTVPASGE 774 P A S P+T+ P L +TP T TP PT A G Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTT-AGGT 2032 Query: 775 ELENITDFSSSPTRETDPL-GKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNA 833 ++ +S+P+ T PL G P + + + S T + +TE ++ Sbjct: 2033 SIQ-----TSTPSERTTPLAGMP----VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASS 2083 Query: 834 TSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDT-VTEYEVISRENGSFSGKNKSIQMTN 892 ++ + ++ + EG P + PL+ T V E + + I T Sbjct: 2084 SATAEGSSMTISAPS-EGSPLLTSI----PLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138 Query: 893 QTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTV----AFSTESADP-RVSEPVSAGRDA 947 + S + + + PL PVS TV A ST S P S PV+ +A Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198 Score = 80.9 bits (198), Expect = 6e-15 Identities = 167/737 (22%), Positives = 254/737 (34%), Gaps = 112/737 (15%) Query: 261 THKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPA 320 T +++ SP A G + + G T L ++L S+A +T ++P Sbjct: 2725 TSAEASSSPTTAE-GTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT-SIPV 2782 Query: 321 ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALD---VSETTLASSEKPWIVPTAKISE 377 + T + S+ PTT ++P ST TS+ L V+ T +ASSE + T + Sbjct: 2783 TTST----EASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTS 2838 Query: 378 DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA--P 435 P T + SSPTT++ + S + +L SIP T+ +TL+ P Sbjct: 2839 T-----PVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893 Query: 436 SETPF-VPQKLEIFTSPEMQPTTPAPQQTTSIPSTP------------------------ 470 +T V E +SP T P T S STP Sbjct: 2894 VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV 2953 Query: 471 -KRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTH 529 R P TT+ GT P + T T T ++ LS Sbjct: 2954 DTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPAD 3013 Query: 530 TKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSP--SPEVSYTTPAPKDV 587 T + A P T+ IP + P + T+P PE S + P D Sbjct: 3014 TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDS 3073 Query: 588 LLPHKPYPEVSQSEPAPLETRGIPF------------IPMISPSPSQEELQTTLEETDQS 635 P EVS S P P E +P +P +S +P +TL T Sbjct: 3074 NSPVVTSTEVS-SSPTPAEGTSMPISTYSEGSTPLTGVP-VSTTPVTSSAISTLSTTPVD 3131 Query: 636 TQEPFT--------------TKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQA 681 T P T T +P +T +T + +T+ +S+ + Sbjct: 3132 TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTL----SAT 3187 Query: 682 PRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPI 741 P + S ++T T GT P P +P +N A I+S Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILS---- 3243 Query: 742 TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGP 801 TTP +TP T T + ++P S E T +S P T Sbjct: 3244 TTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPS-EGSTPLTSMPVSTTT---------- 3292 Query: 802 HVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWE 861 + + S S T + P ++ ++SPP T++ P+ + Sbjct: 3293 ----VASSETSTLSTTPADTSTPVTTYSQA-SSSPPIADGTSM--------PTSTYSEGS 3339 Query: 862 KPL-NDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKN----- 915 PL N + + V+S E + S T T ST +L P T+ + + Sbjct: 3340 TPLTNMSFSTTPVVSSEASTLSTTPVDTS-TPVTTSTEASLSPTTAEGTSIPTSSPSEGT 3398 Query: 916 -PLGEGPVSNTVAFSTE 931 PL PVS T S+E Sbjct: 3399 TPLASMPVSTTPVVSSE 3415 Score = 79.7 bits (195), Expect = 1e-14 Identities = 169/740 (22%), Positives = 263/740 (35%), Gaps = 113/740 (15%) Query: 260 VTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKT-QLAKNETLAL 318 +T +++ SP A G I G T PAS M + + T + +T L Sbjct: 307 ITSTEASSSPTTAE-GTSIPTSTYTEGSTPLT-STPASTMPVATSEMSTLSITPVDTSTL 364 Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 S P +A T++ T+ + P T+ + VS +ASSE T+ I D Sbjct: 365 VTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTN--MPVSTILVASSEAS---TTSTIPVD 419 Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438 SK T + SSPTT+++ I+ S + L S+P T+ + L S T Sbjct: 420 SKTFV--TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNL--STT 475 Query: 439 PFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISK 498 P V K ++ TS E + P + + STP P T+ + + P S Sbjct: 476 P-VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTP--------LTSMSVSTMPVASS 526 Query: 499 SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQT--PRAPPKPKTSPRPRIPQTQ 556 TTP T + S E + + P+ T P + P ++P +P + Sbjct: 527 EASTLSTTPVDTST-------PVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVST 579 Query: 557 PVPKVPQRVTAKPKTSP---------SPEVSYTTPAPKDVLLPHKPYPE----------- 596 + V + T+P S E S ++ + +P Y E Sbjct: 580 RL--VVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVS 637 Query: 597 ---VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKT 653 V+ SE + L T + ++ S TT E T T P T+ T Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697 Query: 654 TQAPHRFYTTVRPRTSD-KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPR 712 T +T+ D + + + P+ AD ++ PT P PL Sbjct: 698 TLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTAD-----GASMPTSTPSEGSTPL--- 749 Query: 713 PTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPAS 772 T P S +++S +T L +TP T T + PT Sbjct: 750 --------------TSMPVSKTLLTSSEAST--LSTTPLDTSTHITTSTEASCSPTT-TE 792 Query: 773 GEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGN 832 G + T SP + P+ + + P+ S S T P +TE + Sbjct: 793 GTSMPISTPSEGSPLLTSIPVS--------ITPVTSPEASTLSTTPVDSNSPVTTSTEVS 844 Query: 833 ATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTN 892 ++ P + T EG + P++ T+ IS S + + S +TN Sbjct: 845 SSPTPAEGTSMPTSTYSEGRTPLTSM----PVSTTLVATSAIS--TLSTTPVDTSTPVTN 898 Query: 893 QTFSTVENLKPNTSYEFQVKPKNPLGEG-------PVSNTVAFSTE----SADP-RVSEP 940 ST P TS E P + GEG P S T S+E SA P S P Sbjct: 899 ---STEARSSPTTS-EGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTP 954 Query: 941 VSAGRDAIWTERPFNSDSYS 960 V+ +A T P ++ S Sbjct: 955 VTTSTEA--TSSPTTAEGTS 972 Score = 78.6 bits (192), Expect = 3e-14 Identities = 165/724 (22%), Positives = 249/724 (34%), Gaps = 108/724 (14%) Query: 295 PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR----STKPTT 350 P + E S + T ++ P+E TP +++ P + TP +P ST P Sbjct: 3017 PVTTSTEASSSPTTAEGTGIPISTPSEGSTP----LTSIPVSTTPVAIPEASTLSTTPVD 3072 Query: 351 SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDE-PEISDSYTA 409 S++ V+ T ++SS P + IS S+ P T V ++P TS +S + Sbjct: 3073 SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGV-PVSTTPVTSSAISTLSTTPVD 3131 Query: 410 TSDRILDSI----PPKTSRTLEQPRATLAPSETP--FVPQKLEIFTSPEMQPTTPAPQQT 463 TS + S P TS P +T + TP ++P + S E + P T Sbjct: 3132 TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDT 3191 Query: 464 TSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPL 523 ++ +T TT+ GT P + S T T P +S P Sbjct: 3192 STPVTTSTE---------ATSSTTAEGTSIPTSTPSEGMTPLTSVP-----VSNTPVASS 3237 Query: 524 SPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR----VTAKP---KTSPSPE 576 + T P TP +S P T P +T+ P T S E Sbjct: 3238 EASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSE 3297 Query: 577 VSYTTPAPKDVLLPHKPYPEVSQSEP------APLETRGIPFIPM----ISPSPSQEELQ 626 S + P D P Y + S S P P T P+ S +P Sbjct: 3298 TSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEA 3357 Query: 627 TTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSG 686 +TL T T P TT T T A T P P V P S Sbjct: 3358 STLSTTPVDTSTPVTTS---TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSS 3414 Query: 687 ---------ADRNVSVD-----STHPTKKPGTRRPPLPPRPTHPRRKPL---PPNNVTGK 729 D N V S+ PT GT LP T PL P + Sbjct: 3415 EVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT---SLPTSTTSEGSTPLSIMPLSTTPVA 3471 Query: 730 PGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPAS--GEELENITDF----- 782 A +S+ P+ T STP T +P T + ++P S GE +T+ Sbjct: 3472 SSEASTLSTTPVDT----STPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527 Query: 783 ----SSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQ 838 S + T T P+ F V + +SP ++ + R +EG+++ Sbjct: 3528 PVASSEASTLSTTPVDSNTF----VTSSSQASSSPATLQVTTMRM--STPSEGSSSLTTM 3581 Query: 839 NPPTNLTVVTVEGCPSFVILDWEKPL------NDTVTEYEVISRENGSFSGKNKSIQMTN 892 + + PS +D P+ N T T EVI+ + S + + + Sbjct: 3582 LLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP 3641 Query: 893 QTFSTVENLKPNTSYEFQVKPKNP------LGEGPVS---NTVAFST--ESADPRVSEPV 941 + ++V + T+ V P + PV+ T+ T E + P + PV Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701 Query: 942 SAGR 945 S R Sbjct: 3702 STTR 3705 Score = 75.9 bits (185), Expect = 2e-13 Identities = 151/758 (19%), Positives = 256/758 (33%), Gaps = 95/758 (12%) Query: 249 PITIIKQVIQNVTHKDSAKSPEKAPLGGV-------ILVHLIIPGLNETTVKLPASLMFE 301 P+T + + T D A P P G + L+ T P Sbjct: 718 PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTH 777 Query: 302 ISDALKTQLAKNET--LALPAESKTPEVEKISARPTTVTPETVPR----STKPTTSSALD 355 I+ + + + T ++P + + +++ P ++TP T P ST P S++ Sbjct: 778 ITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPV 837 Query: 356 VSETTLASSEKP---WIVPTAKISED---------SKVLQPQTATYDVFSSPTTSDEPEI 403 + T ++SS P +PT+ SE S L +A + ++P + P Sbjct: 838 TTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVT 897 Query: 404 SDSYTATSDRILD--SIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQ 461 + + +S + S+P T P ++ S TP V + ++ + +TP Sbjct: 898 NSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPV-T 956 Query: 462 QTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP----KISKSPEPTW-TTPAPGKTQFIS 516 +T S+P P + P T+ T TP ++ S T TTP T Sbjct: 957 TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNT---- 1012 Query: 517 LKPKIPLSPEVTHTKPAP----KQTPRAPPKPKTSPRPRIP--QTQPVPKVPQRVTAKPK 570 PL+ + P P P + P ++P R+P T ++ P Sbjct: 1013 -----PLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA 1067 Query: 571 TSPSPEVSYTTPAPKDVL-----LPHKPYPE--------------VSQSEPAPLETRGIP 611 + +P +Y+ + +P Y E V SE + L T + Sbjct: 1068 DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVD 1127 Query: 612 FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD- 670 ++ S TT E T T P P + TT T+ D Sbjct: 1128 TSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS 1187 Query: 671 KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKP 730 K + + + P A+ ++ PT PG R PL P R P+ + Sbjct: 1188 KTQVATSTEASSPPPTAE-----VTSMPTSTPGERSTPLTSMPV--RHTPVASS------ 1234 Query: 731 GSAGIISSGPI-TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENI---TDFSSSP 786 A +S+ P+ T+ P+ ++ + +P T + T L +I T +SP Sbjct: 1235 -EASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293 Query: 787 TRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTV 846 T KGP V N S + +T +P + P N T+ Sbjct: 1294 EASTLLTTPVDTKGPVV-----TSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTL 1348 Query: 847 VTVEGCP--SFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPN 904 V S +D P+ + + G+ + + T S + P Sbjct: 1349 VASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPV 1408 Query: 905 TSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVS 942 S E P+ T A +T S P +E +S Sbjct: 1409 VSSEASTLSATPVDTSTPGTTSAEATSS--PTTAEGIS 1444 Score = 71.6 bits (174), Expect = 4e-12 Identities = 125/486 (25%), Positives = 181/486 (37%), Gaps = 52/486 (10%) Query: 308 TQLAKNETLAL---PAESKTPEV--EKISARPTTVTPETVPRSTKPTTSSALD---VSET 359 T +A +ET L PA++ TP + S+ TT ++P ST S+ L VS Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTR 1111 Query: 360 TLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIP 419 + SSE + T D+ + P T + + SSPTT++ I S + L S+P Sbjct: 1112 LVVSSEASTLSTTPV---DTSI--PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 1166 Query: 420 PKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRP--- 476 T+ + TL S TP V K ++ TS E P + T+ STP R P Sbjct: 1167 VSTTLVVSSEANTL--STTP-VDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTS 1223 Query: 477 KPPRTKPERTTSAGTI--TPKISKSPEPT--WTTPAPGKTQFISLKPKIPLSPEVTHTKP 532 P R P ++ A T+ +P + +P T T+ +P + SL P S T Sbjct: 1224 MPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSL-PTSTTSEGSTLLTS 1282 Query: 533 APKQTPRAPPKPKTSPRPRIPQTQPV-PKVPQRVTAKPKTSPSPE--VSYTTPAPKDVLL 589 P T TSP T PV K P + + +SP+P S T + Sbjct: 1283 IPVSTTLV-----TSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRT 1337 Query: 590 PHKPYPE----VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645 P P V+ S + L T + ++ S TT E T P P Sbjct: 1338 PLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP 1397 Query: 646 RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTR 705 T+ TT +T+ D PG A S PT G Sbjct: 1398 LTSIPVSTTPVVSSEASTLSATPVDTS--TPGTTSAEATSS-----------PTTAEGIS 1444 Query: 706 RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPI--TTPPLRSTP-RPTGTPLERIET 762 P P K +P +N A +S+ P+ +P + ST + TP E Sbjct: 1445 IPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504 Query: 763 DIKQPT 768 I P+ Sbjct: 1505 AISTPS 1510 Score = 70.9 bits (172), Expect = 6e-12 Identities = 170/737 (23%), Positives = 245/737 (33%), Gaps = 112/737 (15%) Query: 294 LPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISAR--PTTVTPETVPRSTKPTTS 351 +P S S A+ T P ++ TP AR PTT ++P ST S Sbjct: 2166 MPVSTTVVASSAIST------LSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGS 2219 Query: 352 SALDVSETTLASSEKPWIVPTAKISEDSKV--LQPQTATYDVFSSPTTSDEPEISDSYTA 409 + T++ S P + A + V P T + + SSPTT++ I S + Sbjct: 2220 TPF----TSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 2275 Query: 410 TSDRILDSIPPKTSRTLEQPRATLA----PSETPFVPQKLEIFTSPEMQPTTPAPQQTTS 465 L SIP + +TL+ S TPF E + P T P T+S Sbjct: 2276 EGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFT-TSTEASSPPPTAEGTSMPTSTSS 2334 Query: 466 IPSTPKRRPRPKPP-----RTKPERTTSAGTITP-----KISKSPEPTWTTPAPGKTQF- 514 +TP R T TT A T TP + SP T P T Sbjct: 2335 EGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394 Query: 515 ---------ISLKPKIPLSPEVTHTKPAPKQTP-----RAPPKPKTSPRPRIPQTQPVPK 560 +S P + T P TP A P T+ IP + P Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454 Query: 561 VPQRVTAKPKTSP--SPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF------ 612 + T+P S E + P D P E S S P E +P Sbjct: 2455 TTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEAS-SSPTTAEDIVVPISTASEG 2513 Query: 613 ------IPMISPSPSQEELQTTLEETDQSTQEPF--TTKIPRTTELAKTTQAPHRFY--- 661 IP +S +P +TL T + P +T+I + A+ T P Y Sbjct: 2514 STLLTSIP-VSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEG 2572 Query: 662 -TTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV-----DSTHPTKKPGTRRPPLPPRPTH 715 T +R + + D ++ V S+ PT T P P Sbjct: 2573 STPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVS 2632 Query: 716 PRRKPLPPNNVTGKPGSAGIISSGPITTPPLRST--------------PRPTGTPLERIE 761 + + + A +S+ P+ T L +T PT TP ER Sbjct: 2633 TSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERST 2692 Query: 762 --TDIKQPTVPASGEELENIT----DFSSSPTRETDPLGKP-RFKGPHVRYIQKPDNSP- 813 T+I T + E ++ D S+ T + P +G +R D S Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTP 2752 Query: 814 -CSITDSVKRFPKEEATEGNATSPPQNPP--------TNLTVVTVEGCPSFVILDWEKPL 864 SI S EA+ + T+ + P ++ T V P+ + PL Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812 Query: 865 ND-TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG--- 920 V V S E G+ S T T ST + P T+ E V P + EG Sbjct: 2813 TSMPVNHTPVASSEAGTLSTTPVDTS-TPVTTSTKASSSPTTA-EGIVVPISTASEGSTL 2870 Query: 921 ----PVSNTVAFSTESA 933 PVS T S+E++ Sbjct: 2871 LTSIPVSTTPVASSEAS 2887 Score = 67.8 bits (164), Expect = 5e-11 Identities = 142/663 (21%), Positives = 222/663 (33%), Gaps = 80/663 (12%) Query: 296 ASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE--TVPRSTKP---TT 350 +S M +S A +L + TP A + TPE T+P+ST T Sbjct: 158 SSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTP 217 Query: 351 SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTAT 410 +++ S +ASSE ++ T ++ P T + SSPTT++ P +S+S + Sbjct: 218 LTSMPASTMKVASSEAITLLTTPV-----EISTPVTISAQASSSPTTAEGPSLSNSAPSG 272 Query: 411 SDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-ST 469 L +P + +TL S TP + + TS E ++P + TSIP ST Sbjct: 273 GSTPLTRMPLSVMLVVSSEASTL--STTP-AATNIPVITSTEAS-SSPTTAEGTSIPTST 328 Query: 470 PKRRPRP---KPPRTKPERTTSAGT--ITPKISKSPEPTWTTPA--PGKTQFISLKPKIP 522 P P T P T+ T ITP + + T T P+ P + S+ Sbjct: 329 YTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTS-T 387 Query: 523 LSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 582 LS T P T ++ ++ ++ P T+ ++ +TP Sbjct: 388 LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447 Query: 583 APKDVLLPHKPY--PEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPF 640 + L P V+ SE + L T + ++ S T E T P Sbjct: 448 SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507 Query: 641 TTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700 P T+ T +T+ D +A S S+ PT Sbjct: 508 EGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSI----PTS 563 Query: 701 KPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI 760 P PL P R + T TTP +T T + Sbjct: 564 TPSEGSTPLTNMPVSTRLVVSSEASTTS-------------TTPADSNTFVTTSSEASSS 610 Query: 761 ETDIKQPTVPAS--GEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITD 818 T + ++P S E IT S S T + + S S T Sbjct: 611 STTAEGTSMPTSTYSERGTTITSMSVSTT-----------------LVASSEASTLSTTP 653 Query: 819 SVKRFPKEEATEGNATSPPQNPPTNLTVVTVEG--CPSFVILDWEKPLNDTVTEYEVISR 876 P +TE ++S T EG P+ + PL +++ Sbjct: 654 VDSNTPVTTSTEATSSS-----------TTAEGTSMPTSTYTEGSTPLTSMPVNTTLVAS 702 Query: 877 ENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQV------KPKNPLGEGPVSNTVAFST 930 S T T ST + P T+ + + PL PVS T+ S+ Sbjct: 703 SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762 Query: 931 ESA 933 E++ Sbjct: 763 EAS 765 Score = 60.1 bits (144), Expect = 1e-08 Identities = 162/725 (22%), Positives = 241/725 (33%), Gaps = 124/725 (17%) Query: 285 PGLNETTVKLPASLMFEISDALK------TQLAKNETLAL---PAESKTPEVEKISARPT 335 P + E T LP S E S L T +A +E L P ++ TP ++ PT Sbjct: 3440 PTIAEGT-SLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVT---TSSPT 3495 Query: 336 TVTPETVPRSTKPTTSSA--------LDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA 387 +P T ++ PT+++ + VS T +ASSE + T P + Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT-----------PVDS 3544 Query: 388 TYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVP--QKL 445 V SS S P T + T+ L T + + TP P + Sbjct: 3545 NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRS 3604 Query: 446 EIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTW 504 T+ +TP P + ++P STP P P TTS TI+ + S P Sbjct: 3605 TPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPL--TIMPVSTTSV-TISEAGTASTLPVD 3661 Query: 505 T-TPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQ-PVPKVP 562 T TP TQ +S P P + P+ TP T+ R+ ++ P Sbjct: 3662 TSTPVITSTQ-VSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTT---RVTSSEGSTLSTP 3717 Query: 563 QRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQ 622 VT+ P T+ + +S + + P + + T + P S +PS Sbjct: 3718 SVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPE-SSTPSI 3776 Query: 623 EELQTTLEETDQSTQEPFTTKIPRTTEL-AKTTQAPHRFYTTV--------RPRTSDKPH 673 + T++ T S T + TT + TT TTV P + Sbjct: 3777 PSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836 Query: 674 IRPGVKQAP-------------------------RPSGADRNVSVDSTHPTKKPGTRRPP 708 PG P S + V +T PT PG Sbjct: 3837 TPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS 3896 Query: 709 LPP---------------RPTHPRRKPLPPNNVT--GKPGSAGIISSGPITTPPLRSTPR 751 PP PT P + + +T PG+ I S P+T+ P Sbjct: 3897 TPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPA 3956 Query: 752 PTG---TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQK 808 TG TP+ T++ P+ +S T S S T+E F P + Sbjct: 3957 TTGAVSTPV-ITSTELNTPSTSSSS------TTTSFSTTKE--------FTTPAMTTAAP 4001 Query: 809 PDNSPCSITDSVKRFPKEEATEGNAT-SPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDT 867 S S R T +T S P T+ +V T PS E T Sbjct: 4002 LTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSS-----ESSRPST 4056 Query: 868 VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVA 927 +T + + +F + S T ST N + T+ + KP P T A Sbjct: 4057 ITSHTI----PPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTA 4112 Query: 928 FSTES 932 T + Sbjct: 4113 VPTNT 4117 Score = 53.1 bits (126), Expect = 1e-06 Identities = 95/399 (23%), Positives = 144/399 (36%), Gaps = 73/399 (18%) Query: 285 PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344 P E T +P S E S L T L ++ P+E+ T Sbjct: 3795 PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEAST-------------------L 3835 Query: 345 STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTT------- 397 ST P +S ++ T S P V T +IS S+ P T + PT+ Sbjct: 3836 STPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIA 3895 Query: 398 SDEP-EISDSYTATSDRI-LDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP 455 S P + S ++T ++D +IP T+ ++ P T F+P ++ ++ P Sbjct: 3896 STPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFP 3955 Query: 456 TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFI 515 T T I ST P +TS+ + T S + E +TTPA Sbjct: 3956 ATTGAVSTPVITSTELNTP-----------STSSSSTTTSFSTTKE--FTTPA------- 3995 Query: 516 SLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSP 575 + PL+ T P+ TPR + T+ + T P VT +P T PS Sbjct: 3996 -MTTAAPLTYVTMSTAPS---TPRTTSRGCTTSASTLSATS-TPHTSTSVTTRPVT-PSS 4049 Query: 576 EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQS 635 E S + + P +P S P P S + + E + T T S Sbjct: 4050 ESSRPSTITSHTIPP--TFPPAHSSTP--------PTTSASSTTVNPEAVTTMTTRTKPS 4099 Query: 636 TQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHI 674 T+ TT P T A T TT++ + P + Sbjct: 4100 TR---TTSFPTVTTTAVPTN------TTIKSNPTSTPTV 4129 Score = 50.8 bits (120), Expect = 7e-06 Identities = 112/483 (23%), Positives = 165/483 (34%), Gaps = 70/483 (14%) Query: 422 TSRTLEQPRATLAPSETPFVPQKLEIFTS--PEMQPT--TPAPQQTTSIPSTPKRRPRPK 477 TS + +PR L+ S P + TS P + T TP +TTS ++ P Sbjct: 72 TSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPS 131 Query: 478 PPRTKPERTTSAGTITPKISKSPEP-------TWTTPAPGKTQFISLKPKIPLSPEVTHT 530 TT GT P + S E T P P + SL K+ +S +T + Sbjct: 132 STEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTS 191 Query: 531 KPAPKQ--TPRAPPKPK------TSPRPRIPQ--------------TQPVP-----KVPQ 563 A TP + PK ++P +P T PV + Sbjct: 192 TQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISA 251 Query: 564 RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPE--VSQSEPAPLET----RGIPFIPM-- 615 + ++ P T+ P +S + P+ L P V SE + L T IP I Sbjct: 252 QASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTE 311 Query: 616 ISPSPSQEE-----LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD 670 S SP+ E T E + T P +T T+E++ + P T V TS Sbjct: 312 ASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLV--TTST 369 Query: 671 KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKP 730 +P P +A S +S ST T P + + P+ Sbjct: 370 EPSSLPTTAEA--TSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTA 427 Query: 731 GSAGIISSGPIT---TPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT----DFS 783 A SS P T T STP TPL T + T P + E N++ D Sbjct: 428 SEA---SSSPTTAEDTSIATSTPSEGSTPL----TSMPVSTTPVASSEASNLSTTPVDSK 480 Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITD-SVKRFPKEEATEGNATSPPQNPPT 842 + T T+ P + P +T SV P + ++ P + T Sbjct: 481 TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTST 540 Query: 843 NLT 845 +T Sbjct: 541 PVT 543 Score = 45.1 bits (105), Expect = 4e-04 Identities = 66/262 (25%), Positives = 97/262 (37%), Gaps = 17/262 (6%) Query: 238 TVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNE-TTVKLPA 296 T+P P I T T S P+ I V +I G TT+ +P+ Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS 3943 Query: 297 S-LMFEISDALK-TQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSAL 354 + + +D T A + + E TP S+ TT + T T P ++A Sbjct: 3944 TPVTSSTADVFPATTGAVSTPVITSTELNTPST---SSSSTTTSFSTTKEFTTPAMTTAA 4000 Query: 355 DVSETTLASSEKPWIVP----TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTAT 410 ++ T++++ T S S P T+T V + P T E S T T Sbjct: 4001 PLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTST-SVTTRPVTPSS-ESSRPSTIT 4058 Query: 411 SDRILDSIPPKTSRTLEQPRATLAPSET--PFVPQKLEIFTSPEMQPTTPAPQQTTSIPS 468 S I + PP S T P T A S T P + T P + T+ TT++P+ Sbjct: 4059 SHTIPPTFPPAHSST---PPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPT 4115 Query: 469 TPKRRPRPKPPRTKPERTTSAG 490 + P T P TT G Sbjct: 4116 NTTIKSNPTSTPTVPRTTTCFG 4137 Score = 42.0 bits (97), Expect = 0.003 Identities = 76/319 (23%), Positives = 116/319 (36%), Gaps = 32/319 (10%) Query: 231 STYDQDHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLI---IPGL 287 ST D + P K +I +V T + S S PL +++ + PG Sbjct: 3836 STPPGDTSTPLLTSTKAGSFSIPAEV---TTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892 Query: 288 N-ETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRST 346 + +T L S F S T A T+ + + T V I+ T T +P + Sbjct: 3893 SIASTPPLDTSTTFTPS----TDTASTPTIPV---ATTISVSVITEGSTPGTTIFIPST- 3944 Query: 347 KPTTSSALDVSETTLASSEKPWIVPTA--KISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404 P TSS DV T + P I T S S +T F++P + ++ Sbjct: 3945 -PVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003 Query: 405 DSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIF-TSPEMQPTTPAPQQT 463 +T+ S P TSR +TL+ + TP + +P + + P+ + Sbjct: 4004 YVTMSTAP----STPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITS 4059 Query: 464 TSIPSTPKRRPRPKPPRTKPERTT-SAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIP 522 +IP T PP T TT + +T +++ T TT P T Sbjct: 4060 HTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVT--------TT 4111 Query: 523 LSPEVTHTKPAPKQTPRAP 541 P T K P TP P Sbjct: 4112 AVPTNTTIKSNPTSTPTVP 4130 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 84.0 bits (206), Expect = 7e-16 Identities = 146/646 (22%), Positives = 234/646 (36%), Gaps = 103/646 (15%) Query: 243 VPRKLIPITIIKQVIQNVTHKDSAKS-PEKAPLGGVILVHLIIPGLNETTVKLPASLMFE 301 +P + +P+ + K+ + K PEK L V + P T ++ S+ F Sbjct: 10299 IPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVL--VPKKEAVPPAKGRTVLEEKVSVAFR 10356 Query: 302 ----ISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVS 357 + + L+ ++ + E +P E + EVE+ +V Sbjct: 10357 QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEE-----------------GEFHEVE 10399 Query: 358 ETTLASSEKPWIVPTAKISEDSKVLQP-QTATYDVFSSPTTSDE-PEISDSYTATSDRIL 415 E E+ + ++ + +V++ + +VF P + PEIS+ Sbjct: 10400 E--FIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI-------- 10449 Query: 416 DSIPPKTSRTLEQPRATLAPSETPFVPQKL---EIFTSPEMQ--PTTPAPQQTTSIPSTP 470 IPPK T PR P++ P VP+K+ E PE P T P+ P Sbjct: 10450 --IPPKKPPTKVVPRKE-PPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP 10506 Query: 471 KRRPRPKPPRTKPERTTSAGTITPKISKSPE---PTWTTPAPGKTQFISLKPKIPLS--P 525 +++ P PP KPE PK+ ++P+ P P P KP++P + P Sbjct: 10507 EKKV-PVPPAKKPEAPP------PKVPEAPKEVVPEKKVPVPPPK-----KPEVPPTKVP 10554 Query: 526 EVTHTKPAPKQTPRA-PPKPKTSPRPRIPQTQ----PVPKVPQRVTAKPKTSP------- 573 EV K+ P A PPKP+ SP P +P+ P KVP KP+ +P Sbjct: 10555 EVPKAAVPEKKVPEAIPPKPE-SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP 10613 Query: 574 ---SPEVSYTTPAPKDVLLPHKPYPEVSQ-SEPAPLETRGIPFIPMISPSPS--QEELQT 627 PE P PK +P PEV + + P IP P SP P +E + Sbjct: 10614 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPE-SPPPEVFEEPEEV 10672 Query: 628 TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGA 687 LEE E P + P + V + + P ++ V + P+ Sbjct: 10673 ALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVK--VPEVPKEVVP 10730 Query: 688 DRNVSVDSTHPTKKPGTRRPPLP------PRPTHPRRKPLPPNNVTGKPGSAGIISSGPI 741 ++ V + + P + P +P + P++ +PP V P + + Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV 10790 Query: 742 TTPPLRSTPRPTG-------TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLG 794 P +P P P E I + ++P A EE E P +P Sbjct: 10791 PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE-----VPPPAVPEEP-- 10843 Query: 795 KPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840 K V I+KP+ P + K K + PP P Sbjct: 10844 KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPP 10889 Score = 73.9 bits (180), Expect = 7e-13 Identities = 113/536 (21%), Positives = 195/536 (36%), Gaps = 71/536 (13%) Query: 318 LPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISE 377 +P E K EKI T E V V + + P ++ E Sbjct: 9839 VPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE 9898 Query: 378 DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSE 437 K L+P+ ++ E ++ + + I + E+ + P + Sbjct: 9899 VPKELEPEEVAFE---------EEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVK 9949 Query: 438 TPFVPQKLEIFTSPEMQPTTPAPQQTTS----IPSTPKRRPRPKPPRTKPERTTSAGTIT 493 P VP+K PE + P P++ + +P PK+ P K P P++ Sbjct: 9950 VPEVPRK----PVPEEKKPVPVPKKKEAPPAKVPEVPKK-PEEKVPVLIPKKEKPPPAKV 10004 Query: 494 PKISKSPEPTWTTPAPGKTQFISLKPKIPLSPE--VTHTK---PAPKQTPRAPPKPKTSP 548 P++ K P P P P + + K+P P+ V K PAPK+ P K P Sbjct: 10005 PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVP 10064 Query: 549 RPRIPQTQPVPKVPQRVTAKP-----KTSPSPEVSYTTPAPKDVLLPHKPYPE----VSQ 599 + IP+ + VP++V A P K P P V P ++VL + PE + Sbjct: 10065 KKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP-VPVALPQEEEVLFEEEIVPEEEVLPEE 10123 Query: 600 SEPAPLETRGIPFIPMISPSPSQ---EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQA 656 E P E +P + P + EE + EE +E F + E+ Sbjct: 10124 EEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPV 10183 Query: 657 PHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHP 716 P ++ + ++K + P ++AP P K P + R P Sbjct: 10184 PAP-VPEIKKKVTEKKVVIPKKEEAP---------------PAKVPEVPKKVEEKRIILP 10227 Query: 717 RRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEEL 776 + + + P VT +P PI+ + P +E +E ++ P VP E + Sbjct: 10228 KEEEVLPVEVTEEP------EEEPISEEEIPEEP----PSIEEVE-EVAPPRVP---EVI 10273 Query: 777 ENITDFSSSPT--RETDPLGKPRFKGPHVRY---IQKPDNSPCSITDSVKRFPKEE 827 + + +P + P K K P + +QK + P + + K+ P+++ Sbjct: 10274 KKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKK 10329 Score = 71.6 bits (174), Expect = 4e-12 Identities = 136/649 (20%), Positives = 218/649 (33%), Gaps = 120/649 (18%) Query: 234 DQDHTVPAYVPRKLIPITII--KQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETT 291 ++ P VP L P ++ K+V K A P+ ++ +P Sbjct: 10486 EEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKK 10545 Query: 292 VKLPASLMFEISDALKTQLAKNETLALPAESKTPEV----------EKISARPTTVTPET 341 ++P + + E+ A + E + ES PEV +K+ A P PE Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK-KPEV 10604 Query: 342 VPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEP 401 P + + + +KP + PT K+ E KV P+ + S P Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT-KVPEVPKVAVPEKKVPEAIPPKPESPPP 10663 Query: 402 EISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQ 461 E+ + + + PP + +E+P P T VP K + P+ Sbjct: 10664 EVFEE----PEEVALEEPP--AEVVEEPEPAAPPQVT--VPPKKPVPEKKAPAVVAKKPE 10715 Query: 462 -QTTSIPSTPKRR-PRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLK- 518 +P PK P K P P++ + P++ K P P K + K Sbjct: 10716 LPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV 10775 Query: 519 PKIPLSPEVTHTKPA---PKQTPRAPPKPKTSPRPRIPQTQ------------------- 556 P++P P V KPA P++ PP+ P P+ + Sbjct: 10776 PEVPKKP-VLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834 Query: 557 PVPKVPQ---------------RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSE 601 P P VP+ + A P P PE P K P P P + Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVK 10894 Query: 602 PAPLETRGIP---------------FIPMISPSPSQEELQTTLEETDQSTQEPFTTK--I 644 + + IP P+ P +++++ L E +E K + Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPG-GEKKVRKLLPERKPEPKEEVVLKSVL 10953 Query: 645 PRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGT 704 + E + P + +P + P +P V++ P+ R + PTK P Sbjct: 10954 RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKP-VEEVEVPTVTKRERKI--PEPTKVPEI 11010 Query: 705 RRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDI 764 + P P P P KP P V I PP+ P P P+ Sbjct: 11011 K--PAIPLPA-PEPKPKPEAEVK------------TIKPPPVEPEPTPIAAPV------- 11048 Query: 765 KQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813 TVP G++ E + +P E KP KGP ++ + K SP Sbjct: 11049 ---TVPVVGKKAE-----AKAPKEEA---AKP--KGP-IKGVPKKTPSP 11083 Score = 66.2 bits (160), Expect = 2e-10 Identities = 71/343 (20%), Positives = 128/343 (37%), Gaps = 46/343 (13%) Query: 334 PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFS 393 P V + P K ++ E T E+ + T K+ E SK + PQ + Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVT-KVPEVSKKIVPQKPS----R 9220 Query: 394 SPTTSDEPEISDSYTATSDRILDSIPPK-TSRTLEQPRATLAPSETPFVPQ-KLEIFTSP 451 +P + E+ T ++ S T E+ T+ + V + K+ + S Sbjct: 9221 TPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISK 9280 Query: 452 EMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGK 511 ++P P+ +P P P P P++ P++ K P P P P Sbjct: 9281 RVEPPPKVPE----LPEKPA--PEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVP 9334 Query: 512 TQFISLKPKIPLSPEVTHTKPAPKQTPRAP-PKPKTSPRPRIPQTQ-------------- 556 + + PK+P P+ KP P++ P K K +P ++P+ Q Sbjct: 9335 KKEPAAPPKVPEVPK----KPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390 Query: 557 -------PVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609 VP++P++ + + + P PK LP KP PE + P P+ + Sbjct: 9391 REESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKA 9450 Query: 610 IPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAK 652 P ++ +T +EE +E + +P+ E+ + Sbjct: 9451 -------PPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTR 9486 Score = 65.9 bits (159), Expect = 2e-10 Identities = 160/768 (20%), Positives = 259/768 (33%), Gaps = 127/768 (16%) Query: 243 VPRKLIPITIIKQVIQNVTHKDSAKSPE--KAPLGGVILVHLIIPGLNETTVKLPASLMF 300 VP + +P+ + K+V AK PE K P+ E V +PA Sbjct: 10012 VPEEKVPVPVPKKV-----EAPPAKVPEVPKKPVP-------------EKKVPVPAPKKV 10053 Query: 301 EISDALKTQLAKNETLALPAESK-TPEVEKISARPTTV--------TPETVPRSTKPTTS 351 E A ++ K +P E K TP +K+ A P V P +P+ + Sbjct: 10054 EAPPAKVPEVPKK---LIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110 Query: 352 SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATS 411 + E L E+ + E+ +VL + +E + Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170 Query: 412 DRILDSIPPK--------------TSRTLEQPRATLAP-SETPFVPQKLEIFTSPEMQPT 456 + +L + PK T + + P+ AP ++ P VP+K+E E + Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVE-----EKRII 10225 Query: 457 TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTI-------TPKISKSPEPTWTTPAP 509 P ++ + T + P PE S + P++ K P TP P Sbjct: 10226 LPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVP 10285 Query: 510 GKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPK-----PKTSPRPRI--PQTQPVPKV 561 K + P +S ++ K P P Q APP PK P ++ P+ + VP Sbjct: 10286 KKVE----APPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPA 10341 Query: 562 PQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEV--SQSEPAPLETRGIPFIPMISPS 619 R + K S V++ ++V++ + EV ++ E P E Sbjct: 10342 KGRTVLEEKVS----VAFR----QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEG 10393 Query: 620 PSQEELQTTLEETDQSTQEPFTTKIPRTTEL---------------AKTTQAPHRFYTTV 664 E + E + +E K+ R E+ K + + Sbjct: 10394 EFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPK 10453 Query: 665 RPRTSDKPHIRPGVK--QAPRPSGADRNVSVDS---THPTKKPGTRRPPLPPRPTHPRRK 719 +P T P P K + P+ + V V PTK P LPP+ P +K Sbjct: 10454 KPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV----LPPKEVVPEKK 10509 Query: 720 -PLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASG----E 774 P+PP P + P P + P P P + K P VP + + Sbjct: 10510 VPVPPAKKPEAPPPK--VPEAPKEVVPEKKVPVP--PPKKPEVPPTKVPEVPKAAVPEKK 10565 Query: 775 ELENITDFSSSPTRETDPLGK---PRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEG 831 E I SP E K P K P +KP+ +P + ++ K E+ Sbjct: 10566 VPEAIPPKPESPPPEVPEAPKEVVPEKKVP-AAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624 Query: 832 NATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMT 891 P+ PPT + V P + + P ++ EV + + + + Sbjct: 10625 PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPP-EVFE--------EPEEVALE 10675 Query: 892 NQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSE 939 VE +P + V PK P+ E VA E +V E Sbjct: 10676 EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPE 10723 Score = 65.1 bits (157), Expect = 3e-10 Identities = 83/351 (23%), Positives = 131/351 (37%), Gaps = 39/351 (11%) Query: 536 QTPRAPPK----------PKTSPRPRIPQTQP---VPKVPQRVTAKPKTSPSPEVSYTTP 582 + P+APPK PK P +P+ +P VP+VP+++ + K E Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPT 10493 Query: 583 APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT 642 +VL P + PE P + P P + +P + + + E T Sbjct: 10494 KVPEVLPPKEVVPEKKVPVPPAKKPEAPP--PKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10551 Query: 643 KIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV-----DSTH 697 K+P E+ K + + P+ P P V +AP+ ++ V Sbjct: 10552 KVP---EVPKAAVPEKKVPEAIPPKPESPP---PEVPEAPKEVVPEKKVPAAPPKKPEVT 10605 Query: 698 PTKKPGTRRPPLPPR--PTHPRRKP-LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTG 754 P K P + +P + P P +KP +PP V P A P PP +P P Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665 Query: 755 TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKP--RFKGPHVRYIQKPDNS 812 E E +++P EE E ++P + T P KP K P V +KP+ Sbjct: 10666 FE-EPEEVALEEPPAEVV-EEPE-----PAAPPQVTVPPKKPVPEKKAPAV-VAKKPELP 10717 Query: 813 PCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKP 863 P + + K E+ P+ PP + V E P + +KP Sbjct: 10718 PVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKP 10768 Score = 56.6 bits (135), Expect = 1e-07 Identities = 123/629 (19%), Positives = 222/629 (35%), Gaps = 93/629 (14%) Query: 318 LPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSE-----------TTLASSEK 366 +P TPE +K + VT + V + K + +++ TTL ++ Sbjct: 8965 IPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKA 9024 Query: 367 PWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTL 426 P I+ + +E+ K++ T + + E+ A + K Sbjct: 9025 PEIIDVSSKAEEVKIM-------------TITRKKEVQKEKEAVYE--------KKQAVH 9063 Query: 427 EQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERT 486 ++ R + E P+ ++E +T P QP P + + K + E Sbjct: 9064 KEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAK----KEVHEEWEED 9119 Query: 487 TSAGTITPKISKS---PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTP--RAP 541 G + + E W A + + I ++ ++ E +H + P + P +AP Sbjct: 9120 FEEGQEYYEREEGYDEGEEEWEE-AYQEREVIQVQKEVY---EESHERKVPAKVPEKKAP 9175 Query: 542 PKPKTSPRPRIPQTQPVPKVPQRVTA-KPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600 P PK +P I + + K +R+ K + + PEVS ++P KP Q Sbjct: 9176 PPPKVIKKPVI---EKIEKTSRRMEEEKVQVTKVPEVSKK-------IVPQKPSRTPVQE 9225 Query: 601 EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660 E ++ + M+ S+E++ T+E + +P E+ K + Sbjct: 9226 EVIEVKVPAVHTKKMVI---SEEKMFFA-----SHTEEEVSVTVP---EVQKEIVTEEKI 9274 Query: 661 YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720 + + R P + P + + P P + V + P + P +P +P +KP Sbjct: 9275 HVAISKRVEPPPKV-PELPEKPAP---EEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKP 9330 Query: 721 LP-PNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVP---ASGEEL 776 +P P P + P+ P P P E K P V + E++ Sbjct: 9331 VPVPKKEPAAPPKVPEVPKKPV---PEEKIPVPVAKKKEA--PPAKVPEVQKGVVTEEKI 9385 Query: 777 ENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATE------ 830 +T SP + P+ K P R V PK+ E Sbjct: 9386 TIVTQREESPPPAVPEI--PKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVP 9443 Query: 831 ---GNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNK- 886 PP+ + TVV + + L + P VT +EV + E S+S + + Sbjct: 9444 VPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEG 9503 Query: 887 -SIQMTNQTFSTVENLKPNTSYEFQVKPK 914 SI + + E T YE +P+ Sbjct: 9504 VSISVYREEEREEEEEAEVTEYEVMEEPE 9532 Score = 55.1 bits (131), Expect = 4e-07 Identities = 74/332 (22%), Positives = 111/332 (33%), Gaps = 58/332 (17%) Query: 446 EIFTSPEMQ-PTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTW 504 E T PE P P P++ +P+ PK P K+ K P Sbjct: 9784 EYITEPEKPIPVKPVPEEP--VPTKPKAPPA-------------------KVLKKAVPEE 9822 Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564 P P + PK+P P+ + + + T P ++P P+R Sbjct: 9823 KVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK------PKR 9876 Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF----IPMISPSP 620 V A+ K P P+ + P PEV P LE + F + + Sbjct: 9877 VVAEEK----------VPVPRKEVAPPVRVPEV----PKELEPEEVAFEEEVVTHVEEYL 9922 Query: 621 SQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHR-FYTTVRPRTSDKPHIRPGVK 679 +EE + EE + T+E IP K + P + +P K P K Sbjct: 9923 VEEEEEYIHEEEEFITEEEVVPVIP-----VKVPEVPRKPVPEEKKPVPVPKKKEAPPAK 9977 Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLP-PNNVTGKPGSAGIISS 738 P + V V K P + P +P +P + P+P P V P + Sbjct: 9978 VPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPK 10037 Query: 739 GPITTPPLRSTPRPTGTPLERIETDIKQPTVP 770 P+ P + P P +E K P VP Sbjct: 10038 KPV---PEKKVPVPAPKKVE--APPAKVPEVP 10064 Score = 45.4 bits (106), Expect = 3e-04 Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 25/161 (15%) Query: 824 PKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGS 880 P T N PP NPP L V S V L W +P +D VT Y + +E + Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVT-----KSSVSLSWSRPKDDGGSRVTGYYIERKETST 30373 Query: 881 FSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLG---EGPVSNTVAFS---TESAD 934 + T TV L P+ Y+F++ +N +G P S V + + Sbjct: 30374 DKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQ 30433 Query: 935 PRVSEPVSAGRDAI---WTERPFNSDSYSECKGKQYVKRTW 972 P E +S +D++ W E+P EC G + + W Sbjct: 30434 PGELEILSISKDSVTLQW-EKP-------ECDGGKEILGYW 30466 Score = 41.6 bits (96), Expect = 0.004 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 14/132 (10%) Query: 814 CSITDSVKRFPKEEATEGNATS-------PPQNPPTNLTVVTVEGCPSFVILDWEKPLND 866 C D+ K K E + G+ ++ PP NL V V +F++ WE P+ D Sbjct: 24085 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WEPPIID 24142 Query: 867 ---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVS 923 V Y + RE+ + N S + + +F VENL Y F+V +N G G Sbjct: 24143 GGAKVKNYVIDKRESTRKAYANVSSKCSKTSFK-VENLTEGAIYYFRVMAENEFGVGVPV 24201 Query: 924 NTVAFSTESADP 935 TV + ++A+P Sbjct: 24202 ETVD-AVKAAEP 24212 Score = 40.8 bits (94), Expect = 0.007 Identities = 35/104 (33%), Positives = 47/104 (45%), Gaps = 14/104 (13%) Query: 841 PTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFST 897 P NLT+ V+ V L WE PL D +T Y V RE + + T TF Sbjct: 25202 PVNLTIREVK--KDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFR- 25258 Query: 898 VENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADP-RVSEP 940 +ENL+ SY F+V N G + E+ +P +VSEP Sbjct: 25259 IENLQEGCSYYFRVLASNEYG-------IGLPAETTEPVKVSEP 25295 Score = 40.4 bits (93), Expect = 0.009 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Query: 837 PQNPPTNLTVVT-VEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTN 892 P PPT+ +T E S + LDW++P ++ + Y + R + + + ++ Sbjct: 15291 PLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCP 15350 Query: 893 QTFSTVENLKPNTSYEFQVKPKNPLGEGPVS--NTVAFSTESADPRVSEPVSAGRDAI 948 T VENL + YEF+VK N +GE S V + P + +S D I Sbjct: 15351 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 15408 Score = 40.0 bits (92), Expect = 0.012 Identities = 34/89 (38%), Positives = 40/89 (44%), Gaps = 8/89 (8%) Query: 833 ATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQ 889 AT P PP L VV S +L W KP +D +T Y + R+ GS Sbjct: 28542 ATEQPA-PPRRLDVVDTS--KSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAG-- 28596 Query: 890 MTNQTFSTVENLKPNTSYEFQVKPKNPLG 918 T Q TVE L T YEF+VK KN G Sbjct: 28597 HTKQLTFTVERLVEKTEYEFRVKAKNDAG 28625 Score = 39.3 bits (90), Expect = 0.020 Identities = 115/633 (18%), Positives = 210/633 (33%), Gaps = 101/633 (15%) Query: 217 KTVVGSKKVNGKIQSTYDQDHTVPAY----VPRKLIPITIIKQV------IQNVTHKDSA 266 K +V +K++ I + VP P ++ P+ I K+V + V K Sbjct: 9266 KEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP 9325 Query: 267 KS------PEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPA 320 + P+K P + + + E + +P + E A ++ K + Sbjct: 9326 EEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKG----VVT 9381 Query: 321 ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSK 380 E K V + P PE +P+ P + E + K +P + E+ Sbjct: 9382 EEKITIVTQREESPPPAVPE-IPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKV 9440 Query: 381 VLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPF 440 + A S + + + +++ ++P + T + A E + Sbjct: 9441 AVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHE---VSAEEEWSY 9497 Query: 441 VPQK----LEIFTSPEMQPTTPAPQQTTSIPSTPK------------RRPRPKPPRTKPE 484 ++ + ++ E + A + P+ +R +P E Sbjct: 9498 SEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVT-E 9556 Query: 485 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIP--LSPEVTHTKPAPKQTPRAPP 542 R + PKI E P P K P+ P + PE P PK+ PP Sbjct: 9557 RQEKKIVLKPKIPAKIEE----PPPAKV------PEAPKKIVPEKKVPAPVPKKEKVPPP 9606 Query: 543 KPKTSPRPRIPQTQPVPKV-------PQRVT--------------------AKPKTSPSP 575 K P+ +P+ + PKV P +VT A PK Sbjct: 9607 KVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPE 9666 Query: 576 EVSYTTPAPKDVLLPHK----PYPEVSQSEPAPLETRGIPF-IPMISPSPSQEELQTTLE 630 E P K + L K P +V++ ++ + P P P +E T +E Sbjct: 9667 EPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKE--VTIME 9724 Query: 631 ETDQS-TQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADR 689 E +++ T E + R E + + ++ + P + ++ R + Sbjct: 9725 EKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEE 9784 Query: 690 NVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTP-PLRS 748 + T P K + P P PT P+ PP V K + + P P + Sbjct: 9785 YI----TEPEKPIPVKPVPEEPVPTKPK---APPAKVLKK-----AVPEEKVPVPIPKKL 9832 Query: 749 TPRPTGTPLERIETDIKQPTVPASGEELENITD 781 P P P E + ++ + + E E +T+ Sbjct: 9833 KPPPPKVPEEPKKVFEEKIRISITKREKEQVTE 9865 Score = 38.5 bits (88), Expect = 0.034 Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 29/161 (18%) Query: 535 KQTPRAPPKPKT-SPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP 593 K PR PPKPK+ SP P P + + + SPSP + H P Sbjct: 252 KTPPRIPPKPKSRSPTP--------PSIAAKAQLARQQSPSP-------------IRHSP 290 Query: 594 YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP----RTTE 649 P P P R + IS SP + L Q++ ++P + Sbjct: 291 SPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGY 350 Query: 650 LAKTTQAPHR---FYTTVRPRTSDKPHIRPGVKQAPRPSGA 687 +A +++A R T+ + RT ++ R GV++ SGA Sbjct: 351 VASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGA 391 Score = 38.5 bits (88), Expect = 0.034 Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 8/108 (7%) Query: 840 PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896 PP N+T+ V V L WE P D +T Y + R+ S + Sbjct: 13193 PPLNVTITDVNRFG--VSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSA 13250 Query: 897 TVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADP--RVSEPVS 942 TV ++ Y F+V+ +N +G G S F + ADP R S PV+ Sbjct: 13251 TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPF-VKVADPIERPSPPVN 13297 Score = 38.1 bits (87), Expect = 0.045 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 15/118 (12%) Query: 840 PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTN---Q 893 PPTN+TV V +L W+ P ND V Y + RE + K + +TN + Sbjct: 26280 PPTNITVQDVT--KESAVLSWDVPENDGGAPVKNYHIEKRE----ASKKAWVSVTNNCNR 26333 Query: 894 TFSTVENLKPNTSYEFQVKPKNPLGEGPVSNT---VAFSTESADPRVSEPVSAGRDAI 948 V NL+ Y F+V +N G G + T V + + + P S +D++ Sbjct: 26334 LSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV 26391 Score = 37.4 bits (85), Expect = 0.077 Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 14/161 (8%) Query: 824 PKEEATEGNATSP--PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISREN 878 P E A P P +PP L + + + V L W+ P ND VT Y V Sbjct: 15996 PVETIQRTTARDPIYPPDPPIKLKIGLIT--KNTVHLSWKPPKNDGGSPVTHYIVECLAW 16053 Query: 879 GSFSGKNKSIQMTN-----QTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESA 933 K ++ + N + TVE+L YEF+VK N G S TV + Sbjct: 16054 DPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVG-PCDCQ 16112 Query: 934 DPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYK 974 P + + ++ + E N + ++ KG + TW+K Sbjct: 16113 RPDMPPSIDL-KEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 16152 Score = 37.4 bits (85), Expect = 0.077 Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 6/88 (6%) Query: 837 PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQ 893 P PP + + + S + L W KP+ D VT Y V R+ S + + Sbjct: 27166 PPGPPAKIRIA--DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223 Query: 894 TFS-TVENLKPNTSYEFQVKPKNPLGEG 920 T V NLKP +Y F+V N G+G Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQG 27251 Score = 36.6 bits (83), Expect = 0.13 Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 13/103 (12%) Query: 824 PKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGS 880 P + AT + +PP P +T T S L+W PL D VT Y V +E G Sbjct: 16409 PSDPATARDPIAPPGPPFPKVTDWT----KSSADLEWSPPLKDGGSKVTGYIVEYKEEGK 16464 Query: 881 FS---GKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG 920 GK+K ++ T V LK Y+F+V+ N G G Sbjct: 16465 EEWEKGKDKEVRGTKLV---VTGLKEGAFYKFRVRAVNIAGIG 16504 Score = 36.6 bits (83), Expect = 0.13 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 9/112 (8%) Query: 856 VILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVK 912 +++ W +P+N+ V Y + +E S + + + T +NL+ YEF+V Sbjct: 23439 MVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVY 23498 Query: 913 PKNPLGEGPVS-NTVAFSTESA--DPRVSEPVSAGRDAI---WTERPFNSDS 958 +N +G G S N+ + P EP+ R+ I WT+ ++ S Sbjct: 23499 AENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGS 23550 Score = 36.2 bits (82), Expect = 0.17 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 17/108 (15%) Query: 835 SPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMT 891 SPP P V+ + + + W KPL D +T Y V +++ K SIQ Sbjct: 26085 SPPSKPKI------VDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKT-SIQSL 26137 Query: 892 NQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSE 939 T T+ L Y F+VK N +G S +S+DP++++ Sbjct: 26138 RGTEYTISGLTTGAEYVFRVKSVNKVGASDPS-------DSSDPQIAK 26178 Score = 35.8 bits (81), Expect = 0.22 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 7/100 (7%) Query: 844 LTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN 900 +T VT + C ++ W+ P +D + Y + RE + + + +T +V+N Sbjct: 30833 ITAVTKDSC----VVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKN 30888 Query: 901 LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP 940 L YEF+VK +N GE S T +D + P Sbjct: 30889 LIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP 30928 Score = 35.0 bits (79), Expect = 0.38 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 8/107 (7%) Query: 824 PKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGS 880 P + G+ PP PP+ V + S + L W+ P D + Y V +E G+ Sbjct: 15692 PSDPEVAGDPIFPP-GPPSCPEVK--DKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGT 15748 Query: 881 FSGK--NKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNT 925 K N+ ++ V NLK Y F+VK N GE S+T Sbjct: 15749 TDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT 15795 Score = 35.0 bits (79), Expect = 0.38 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 13/94 (13%) Query: 837 PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRE-------NGSFSGKNK 886 P PPTN VV + + L W KP+ D + Y V R + + N Sbjct: 18496 PPGPPTNFRVV--DTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNA 18553 Query: 887 SIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG 920 + Q+ + F TV +L N YEF+V +N +G G Sbjct: 18554 AAQLVRKEF-TVTSLDENQEYEFRVCAQNQVGIG 18586 Score = 34.7 bits (78), Expect = 0.50 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 7/91 (7%) Query: 836 PPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTF 895 P QN +T VT E C + WE PL++ +E E + K SI ++ T Sbjct: 18004 PCQN--LKVTNVTKENCT----ISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTK 18057 Query: 896 STVE-NLKPNTSYEFQVKPKNPLGEGPVSNT 925 ++ NL N Y F+V +N +G GP T Sbjct: 18058 RLIKANLLANNEYYFRVCAENKVGVGPTIET 18088 Score = 34.7 bits (78), Expect = 0.50 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 5/90 (5%) Query: 837 PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQ 893 P PP V V + + W++P++D +T Y V RE S + Sbjct: 20571 PPGPPEKPEVSNVT--KNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSD 20628 Query: 894 TFSTVENLKPNTSYEFQVKPKNPLGEGPVS 923 V L+ ++YEF+V +N G GP S Sbjct: 20629 LRCKVTGLQEGSTYEFRVSAENRAGIGPPS 20658 Score = 34.7 bits (78), Expect = 0.50 Identities = 46/203 (22%), Positives = 73/203 (35%), Gaps = 22/203 (10%) Query: 856 VILDWEKPLNDTVTE---YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVK 912 V L WEKP D E Y V R++G + K + + T+ L T YEF+V Sbjct: 30447 VTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVF 30506 Query: 913 PKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTW 972 +N G T + + + T+ + + G+ W Sbjct: 30507 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 30566 Query: 973 YKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLTSDQ 1032 Y+ G +L S +YK+ S G+ + + ED + G+ TS + Sbjct: 30567 YR--FGKELIQSRKYKM----SSDGRTHTLTVMTEEQEDEGVYT-CIATNEVGEVETSSK 30619 Query: 1033 L------------PIKEGYFRAV 1043 L P+KE Y+ AV Sbjct: 30620 LLLQATPQFHPGYPLKEKYYGAV 30642 Score = 34.3 bits (77), Expect = 0.65 Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 14/169 (8%) Query: 840 PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896 PP N+TV + ++V WE P+ D + Y V R+ S + + + +F Sbjct: 19789 PPVNVTVKEISKDSAYVT--WEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFR 19846 Query: 897 TVENLKPNTSYEFQVKPKNPLGEGPVSNT--VAFSTESADPRVS---EPVSAGRDAIWTE 951 V NL+ SY F+V +N G G T ++++ P V VS +I + Sbjct: 19847 -VANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWK 19905 Query: 952 RPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFY 1000 +P +SD S G T K+ V SL+Y D GK Y Sbjct: 19906 KP-HSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYS--AKDLTEGKEY 19951 Score = 33.9 bits (76), Expect = 0.85 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 840 PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896 PPT + E FV W+ P ND ++ Y V R+ S + + + T+ Sbjct: 21161 PPTG-PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 21219 Query: 897 TVENLKPNTSYEFQVKPKNPLGEGP 921 L Y+F+VK +N G GP Sbjct: 21220 ATR-LTTGLEYQFRVKAQNRYGVGP 21243 Score = 33.9 bits (76), Expect = 0.85 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 14/97 (14%) Query: 485 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKP 544 R T +P KSPEP +P K+ PK SPE +H K +P + Sbjct: 32654 RVTEKAVTSPPRVKSPEPRVKSPEAVKS------PKRVKSPEPSHPKAV------SPTET 32701 Query: 545 KTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTT 581 K +P ++ Q PV P ++T K S E++ T Sbjct: 32702 KPTPTEKV-QHLPV-SAPPKITQFLKAEASKEIAKLT 32736 Score = 33.1 bits (74), Expect = 1.4 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%) Query: 840 PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896 PP N+ + + + V L W++P D +T Y V R+ S +T Sbjct: 26770 PPRNVRITDIS--KNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQF 26827 Query: 897 TVENLKPNTSYEFQVKPKNPLG 918 + L N+ YEF+V +N +G Sbjct: 26828 IISGLTQNSQYEFRVFARNAVG 26849 Score = 33.1 bits (74), Expect = 1.4 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 8/90 (8%) Query: 837 PQNPPTNLTVVTV-EGCPSFVILDWEKPLNDTVTEY-----EVISRENGSFSGKNKSIQM 890 P NPP TVV V + + V L+W KP+ D E E+ + G + N + Sbjct: 28250 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV 28309 Query: 891 TNQTFSTVENLKPNTSYEFQVKPKNPLGEG 920 +T TV +L+ Y+F+V N G+G Sbjct: 28310 --KTRYTVTDLQAGEEYKFRVSAINGAGKG 28337 Score = 32.7 bits (73), Expect = 1.9 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 16/89 (17%) Query: 839 NPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTF 895 +PP NL V ++ + L W+ PL++ +T Y + R+ K + T Sbjct: 15499 SPPRNLAVTDIKAESCY--LTWDAPLDNGGSEITHYVIDKRD-----ASRKKAEWEEVTN 15551 Query: 896 STVEN------LKPNTSYEFQVKPKNPLG 918 + VE L PN YEF+V+ N G Sbjct: 15552 TAVEKRYGIWKLIPNGQYEFRVRAVNKYG 15580 Score = 32.7 bits (73), Expect = 1.9 Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 15/101 (14%) Query: 824 PKEEATEGNATSPPQNP-PTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRE-- 877 P E + PP P P N+T TV L W KP +T Y V R+ Sbjct: 21347 PSEPMLALDPIDPPGKPVPLNITRHTVT-------LKWAKPEYTGGFKITSYIVEKRDLP 21399 Query: 878 NGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLG 918 NG + N S + N+ TV L + +YEF+V KN G Sbjct: 21400 NGRWLKANFSNILENEF--TVSGLTEDAAYEFRVIAKNAAG 21438 Score = 32.3 bits (72), Expect = 2.5 Identities = 39/124 (31%), Positives = 49/124 (39%), Gaps = 12/124 (9%) Query: 479 PRTKPERTTSAGTITPKIS---KSPE-PTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAP 534 PR + T T +I K P+ P P P T I P + P V P P Sbjct: 8911 PRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIP--TMPIRAVPPEEIPPVVA--PPIP 8966 Query: 535 KQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP 593 P P+ K P RI T+ V K ++V AKPK E P P L+P K Sbjct: 8967 LLLPT--PEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKA 9024 Query: 594 YPEV 597 PE+ Sbjct: 9025 -PEI 9027 Score = 32.3 bits (72), Expect = 2.5 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 22/105 (20%) Query: 100 LIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPN 159 ++ V P PP+ P +L T S++ L W P + P Sbjct: 15286 ILAVDPLGPPTS------------PERLTYTERTKSTITLDWK---EPRSNGGSPI---- 15326 Query: 160 DRFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFGVK 202 + Y I R DK ++ ++CP T +VENL + +YEF VK Sbjct: 15327 -QGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVK 15370 Score = 32.0 bits (71), Expect = 3.2 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 860 WEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 916 W +P+ D ++ Y + R+ S + T V L N+ Y+++V N Sbjct: 27086 WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNA 27145 Query: 917 LGEGPVSNTVAFSTESADP 935 G+GP S F ++ADP Sbjct: 27146 AGQGPFSEPSEF-YKAADP 27163 Score = 31.6 bits (70), Expect = 4.2 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 10/116 (8%) Query: 839 NPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTF 895 +PP NLT + + S V L WE PL D + Y + E G + ++++ + Sbjct: 13293 SPPVNLT--SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELT 13350 Query: 896 STVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP---VSAGRDAI 948 V L+ Y ++V +N G S + T AD EP +SA +D + Sbjct: 13351 YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLT--ADDAFVEPTMDLSAFKDGL 13404 Score = 31.6 bits (70), Expect = 4.2 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%) Query: 847 VTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKP 903 +T E C L W P +D +T Y + RE+ + + +T Q +TV+ L Sbjct: 16628 LTNESCK----LTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQ 16682 Query: 904 NTSYEFQVKPKNPLGEGPVSNT 925 +Y F++ +N +G GP T Sbjct: 16683 GKAYFFRIAAENSIGMGPFVET 16704 Score = 31.6 bits (70), Expect = 4.2 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%) Query: 833 ATSPPQNP--PTNLTVVTVEGCPSFVILDWEKPLNDTVT---EYEVISRENGSFSGKNKS 887 A +P P P NL + + +FV L W +P D + Y V R GS + Sbjct: 18094 AINPIDRPGEPENLHIA--DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH 18151 Query: 888 IQMTNQTFSTVENLKPNTSYEFQVKPKNPLGE 919 +T V+ N YEF+V+ KN GE Sbjct: 18152 KGSIKETHYMVDRCVENQIYEFRVQTKNEGGE 18183 Score = 31.6 bits (70), Expect = 4.2 Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 15/118 (12%) Query: 837 PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQ 893 P +PP + V+ + + L W KP+ D +T Y V R+ S + Sbjct: 23520 PCDPPGTPEPIMVKR--NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIE 23577 Query: 894 TFSTVENLKPNTSYEFQVKPKNPLG--------EGPVS--NTVAFSTESADPRVSEPV 941 T TV L + YEF+V KN G GP++ + V S DP+ + + Sbjct: 23578 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 23635 Score = 31.6 bits (70), Expect = 4.2 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%) Query: 540 APPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSP---SPEVSYTTPAPKDVLLPHKPYPE 596 +PP+ K SP PR+ + V K P+RV + + P SP + TP K LP P+ Sbjct: 32662 SPPRVK-SPEPRVKSPEAV-KSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPK 32719 Query: 597 VSQ 599 ++Q Sbjct: 32720 ITQ 32722 Score = 31.2 bits (69), Expect = 5.5 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 6/86 (6%) Query: 858 LDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPK 914 + W P ND VT Y V RE + + ++ +F V NL P Y F+V Sbjct: 18717 VSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH-VTNLVPGNEYYFRVTAV 18775 Query: 915 NPLGEGPVSNTVAFSTESADPRVSEP 940 N G G V V ++DP +SEP Sbjct: 18776 NEYGPG-VPTDVPKPVLASDP-LSEP 18799 Score = 30.8 bits (68), Expect = 7.2 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 6/89 (6%) Query: 840 PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896 PP +L V + + L W++PL+D +T Y V R+ S S ++ Sbjct: 17312 PPRDLEVSEIRKDSCY--LTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF 17369 Query: 897 TVENLKPNTSYEFQVKPKNPLGEGPVSNT 925 ++L Y F+V +N G GP T Sbjct: 17370 A-KHLNEGNQYLFRVAAENQYGRGPFVET 17397 Score = 30.8 bits (68), Expect = 7.2 Identities = 15/37 (40%), Positives = 21/37 (56%) Query: 105 PAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSW 141 P+PP + +K+C + P V +T SSVFLSW Sbjct: 22822 PSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 22858 Score = 30.8 bits (68), Expect = 7.2 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 829 TEGNATSPPQNPPT-NLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKS 887 T N PP P T ++ +T + +++ W +P++D TE E E G + Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDS----MVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 24949 Query: 888 IQMTNQTFST----VENLKPNTSYEFQVKPKNPLGEGPVSNTVAF 928 + +T + V L SYEF+V +N G G S F Sbjct: 24950 -KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVF 24993 >gi|222418647 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 83.2 bits (204), Expect = 1e-15 Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 42/274 (15%) Query: 403 ISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP----TTP 458 ++ + AT+ + P +++ P T P + + + TS + +P Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSP 160 Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTT------SAGTITPKISKSPE--------PTW 504 APQ TT+ P TP P + P TT SA T P S +P P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220 Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564 TTPAP P PE T P P T P P +S P P+T VP P Sbjct: 221 TTPAP---------PSSSAPPETTAAPPTPSAT---TPAPLSSSAP--PETTAVPPTPSA 266 Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624 T P ++ +P + P P P S PAP ET P+ +P+ S Sbjct: 267 TTLDPSSASAPPETTAAPPTPSATTPAPP------SSPAPQETTA---APITTPNSSPTT 317 Query: 625 LQTTLEETDQSTQEPFTTKI-PRTTELAKTTQAP 657 L ET + TT + +TT + T AP Sbjct: 318 LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351 Score = 79.3 bits (194), Expect = 2e-14 Identities = 93/329 (28%), Positives = 125/329 (37%), Gaps = 50/329 (15%) Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459 +P I SY R +PP + + P P + P P K +P + TT Sbjct: 56 KPFIRKSYKCLHKRCRPKLPPSPNNPPKFPN----PHQPPKHPDKNSSVVNPTLVATTQI 111 Query: 460 PQQT-----TSIPSTPKRRPRPKPPRTKPER-----TTSAGTITPKISKSPEPTWTTPAP 509 P T T I + P P+ T R ++S T+ P S +P+ T P P Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP-P 170 Query: 510 GKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569 + P PE T P P T +APP +S P P+T P P T P Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPP---SSSAP--PETTAAPPTPPATTPAP 225 Query: 570 KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629 +S +P TT AP P S + PAPL + P + P+PS TTL Sbjct: 226 PSSSAP--PETTAAP----------PTPSATTPAPLSSSAPPETTAVPPTPS----ATTL 269 Query: 630 EETDQSTQEPFTTKIP----RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685 + + S P TT P TT ++ AP TT P T+ P+ P AP S Sbjct: 270 DPSSASA-PPETTAAPPTPSATTPAPPSSPAPQE--TTAAPITT--PNSSP-TTLAPDTS 323 Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRPT 714 S TH T T + +PT Sbjct: 324 ----ETSAAPTHQTTTSVTTQTTTTKQPT 348 Score = 75.5 bits (184), Expect = 3e-13 Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 30/283 (10%) Query: 518 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV-----PQRVTAKPKTS 572 +PK+P SP P P Q P+ P K + P + T +P V ++T P + Sbjct: 71 RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130 Query: 573 PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEET 632 P+ + T + ++V + PAP +T P P+PS T Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP------PTPS-----ATTPAP 179 Query: 633 DQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692 S+ P TT P T + TTQAP ++ P T+ P P AP S A + Sbjct: 180 PSSSAPPETTAAPPTP--SATTQAPPS--SSAPPETTAAPPTPPATTPAPPSSSAPPETT 235 Query: 693 V-----DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR 747 +T P + P P P L P++ + P + + TTP Sbjct: 236 AAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295 Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 790 S+P P T I T PT A + ++ S++PT +T Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLA-----PDTSETSAAPTHQT 333 Score = 59.3 bits (142), Expect = 2e-08 Identities = 62/209 (29%), Positives = 84/209 (40%), Gaps = 20/209 (9%) Query: 311 AKNETLALPA--ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368 A +T A P + TP SA P T P +T S+ ETT A P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220 Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 P + S P+T S TT P S + T+ ++PP S T Sbjct: 221 TTP----APPSSSAPPETTAAPPTPSATT-PAPLSSSAPPETT-----AVPPTPSATTLD 270 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTT 487 P + AP ET P T P++PAPQ+TT+ P +TP P P T T+ Sbjct: 271 PSSASAPPETTAAPPTPSATT--PAPPSSPAPQETTAAPITTPNSSPTTLAPDT--SETS 326 Query: 488 SAGTITPKISKSPEPTWT---TPAPGKTQ 513 +A T S + + T T T APG+ + Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355 >gi|222418649 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 83.2 bits (204), Expect = 1e-15 Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 42/274 (15%) Query: 403 ISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP----TTP 458 ++ + AT+ + P +++ P T P + + + TS + +P Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSP 160 Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTT------SAGTITPKISKSPE--------PTW 504 APQ TT+ P TP P + P TT SA T P S +P P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220 Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564 TTPAP P PE T P P T P P +S P P+T VP P Sbjct: 221 TTPAP---------PSSSAPPETTAAPPTPSAT---TPAPLSSSAP--PETTAVPPTPSA 266 Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624 T P ++ +P + P P P S PAP ET P+ +P+ S Sbjct: 267 TTLDPSSASAPPETTAAPPTPSATTPAPP------SSPAPQETTA---APITTPNSSPTT 317 Query: 625 LQTTLEETDQSTQEPFTTKI-PRTTELAKTTQAP 657 L ET + TT + +TT + T AP Sbjct: 318 LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351 Score = 79.3 bits (194), Expect = 2e-14 Identities = 93/329 (28%), Positives = 125/329 (37%), Gaps = 50/329 (15%) Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459 +P I SY R +PP + + P P + P P K +P + TT Sbjct: 56 KPFIRKSYKCLHKRCRPKLPPSPNNPPKFPN----PHQPPKHPDKNSSVVNPTLVATTQI 111 Query: 460 PQQT-----TSIPSTPKRRPRPKPPRTKPER-----TTSAGTITPKISKSPEPTWTTPAP 509 P T T I + P P+ T R ++S T+ P S +P+ T P P Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP-P 170 Query: 510 GKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569 + P PE T P P T +APP +S P P+T P P T P Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPP---SSSAP--PETTAAPPTPPATTPAP 225 Query: 570 KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629 +S +P TT AP P S + PAPL + P + P+PS TTL Sbjct: 226 PSSSAP--PETTAAP----------PTPSATTPAPLSSSAPPETTAVPPTPS----ATTL 269 Query: 630 EETDQSTQEPFTTKIP----RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685 + + S P TT P TT ++ AP TT P T+ P+ P AP S Sbjct: 270 DPSSASA-PPETTAAPPTPSATTPAPPSSPAPQE--TTAAPITT--PNSSP-TTLAPDTS 323 Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRPT 714 S TH T T + +PT Sbjct: 324 ----ETSAAPTHQTTTSVTTQTTTTKQPT 348 Score = 75.5 bits (184), Expect = 3e-13 Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 30/283 (10%) Query: 518 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV-----PQRVTAKPKTS 572 +PK+P SP P P Q P+ P K + P + T +P V ++T P + Sbjct: 71 RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130 Query: 573 PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEET 632 P+ + T + ++V + PAP +T P P+PS T Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP------PTPS-----ATTPAP 179 Query: 633 DQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692 S+ P TT P T + TTQAP ++ P T+ P P AP S A + Sbjct: 180 PSSSAPPETTAAPPTP--SATTQAPPS--SSAPPETTAAPPTPPATTPAPPSSSAPPETT 235 Query: 693 V-----DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR 747 +T P + P P P L P++ + P + + TTP Sbjct: 236 AAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295 Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 790 S+P P T I T PT A + ++ S++PT +T Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLA-----PDTSETSAAPTHQT 333 Score = 59.3 bits (142), Expect = 2e-08 Identities = 62/209 (29%), Positives = 84/209 (40%), Gaps = 20/209 (9%) Query: 311 AKNETLALPA--ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368 A +T A P + TP SA P T P +T S+ ETT A P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220 Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 P + S P+T S TT P S + T+ ++PP S T Sbjct: 221 TTP----APPSSSAPPETTAAPPTPSATT-PAPLSSSAPPETT-----AVPPTPSATTLD 270 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTT 487 P + AP ET P T P++PAPQ+TT+ P +TP P P T T+ Sbjct: 271 PSSASAPPETTAAPPTPSATT--PAPPSSPAPQETTAAPITTPNSSPTTLAPDT--SETS 326 Query: 488 SAGTITPKISKSPEPTWT---TPAPGKTQ 513 +A T S + + T T T APG+ + Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355 >gi|222418645 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 83.2 bits (204), Expect = 1e-15 Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 42/274 (15%) Query: 403 ISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP----TTP 458 ++ + AT+ + P +++ P T P + + + TS + +P Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSP 160 Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTT------SAGTITPKISKSPE--------PTW 504 APQ TT+ P TP P + P TT SA T P S +P P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220 Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564 TTPAP P PE T P P T P P +S P P+T VP P Sbjct: 221 TTPAP---------PSSSAPPETTAAPPTPSAT---TPAPLSSSAP--PETTAVPPTPSA 266 Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624 T P ++ +P + P P P S PAP ET P+ +P+ S Sbjct: 267 TTLDPSSASAPPETTAAPPTPSATTPAPP------SSPAPQETTA---APITTPNSSPTT 317 Query: 625 LQTTLEETDQSTQEPFTTKI-PRTTELAKTTQAP 657 L ET + TT + +TT + T AP Sbjct: 318 LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351 Score = 79.3 bits (194), Expect = 2e-14 Identities = 93/329 (28%), Positives = 125/329 (37%), Gaps = 50/329 (15%) Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459 +P I SY R +PP + + P P + P P K +P + TT Sbjct: 56 KPFIRKSYKCLHKRCRPKLPPSPNNPPKFPN----PHQPPKHPDKNSSVVNPTLVATTQI 111 Query: 460 PQQT-----TSIPSTPKRRPRPKPPRTKPER-----TTSAGTITPKISKSPEPTWTTPAP 509 P T T I + P P+ T R ++S T+ P S +P+ T P P Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP-P 170 Query: 510 GKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569 + P PE T P P T +APP +S P P+T P P T P Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPP---SSSAP--PETTAAPPTPPATTPAP 225 Query: 570 KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629 +S +P TT AP P S + PAPL + P + P+PS TTL Sbjct: 226 PSSSAP--PETTAAP----------PTPSATTPAPLSSSAPPETTAVPPTPS----ATTL 269 Query: 630 EETDQSTQEPFTTKIP----RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685 + + S P TT P TT ++ AP TT P T+ P+ P AP S Sbjct: 270 DPSSASA-PPETTAAPPTPSATTPAPPSSPAPQE--TTAAPITT--PNSSP-TTLAPDTS 323 Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRPT 714 S TH T T + +PT Sbjct: 324 ----ETSAAPTHQTTTSVTTQTTTTKQPT 348 Score = 75.5 bits (184), Expect = 3e-13 Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 30/283 (10%) Query: 518 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV-----PQRVTAKPKTS 572 +PK+P SP P P Q P+ P K + P + T +P V ++T P + Sbjct: 71 RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130 Query: 573 PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEET 632 P+ + T + ++V + PAP +T P P+PS T Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP------PTPS-----ATTPAP 179 Query: 633 DQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692 S+ P TT P T + TTQAP ++ P T+ P P AP S A + Sbjct: 180 PSSSAPPETTAAPPTP--SATTQAPPS--SSAPPETTAAPPTPPATTPAPPSSSAPPETT 235 Query: 693 V-----DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR 747 +T P + P P P L P++ + P + + TTP Sbjct: 236 AAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295 Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 790 S+P P T I T PT A + ++ S++PT +T Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLA-----PDTSETSAAPTHQT 333 Score = 59.3 bits (142), Expect = 2e-08 Identities = 62/209 (29%), Positives = 84/209 (40%), Gaps = 20/209 (9%) Query: 311 AKNETLALPA--ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368 A +T A P + TP SA P T P +T S+ ETT A P Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220 Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 P + S P+T S TT P S + T+ ++PP S T Sbjct: 221 TTP----APPSSSAPPETTAAPPTPSATT-PAPLSSSAPPETT-----AVPPTPSATTLD 270 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTT 487 P + AP ET P T P++PAPQ+TT+ P +TP P P T T+ Sbjct: 271 PSSASAPPETTAAPPTPSATT--PAPPSSPAPQETTAAPITTPNSSPTTLAPDT--SETS 326 Query: 488 SAGTITPKISKSPEPTWT---TPAPGKTQ 513 +A T S + + T T T APG+ + Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 82.0 bits (201), Expect = 3e-15 Identities = 149/674 (22%), Positives = 228/674 (33%), Gaps = 75/674 (11%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P P + K T + + +P + T S S T L K ++P + Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG--FLSE 159 Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438 L ++ + F+ + E S T +++ K ++ P P Sbjct: 160 VNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP- 218 Query: 439 PFVPQKLEIFTSPEMQPTTP---APQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK 495 +P++ P Q TP + QQ I S P +P T+ +T A + Sbjct: 219 --IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276 Query: 496 ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTP-RAPPKPKTSPRPRIPQ 554 + P+ G+ S+KP +P + +P P + P + P K+ P P P Sbjct: 277 DASRPQTKQADIVRGE----SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332 Query: 555 TQPV----PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGI 610 QP P Q T KP P TT P L P KP + + SE E G Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPG----TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 611 PFI---PMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPR 667 + P + +P+Q+ +P T ++ LA Q P P Sbjct: 389 KALAQPPGVGKTPAQQP----------GPAKPPTQQVGTPKPLA---QQPGLQSPAKAPG 435 Query: 668 TSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 727 + P +PG + P S T PTK P P P P P PP Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ--- 492 Query: 728 GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPT-VPASGE-ELENITDFSSS 785 +PGSA S P +T P P P P + K P+ P S + + + S Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGP-AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550 Query: 786 PTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLT 845 + T P+ + P +Q P SP + + PK N T + P Sbjct: 551 AQQSTKPVSQTGSGKP----LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606 Query: 846 VVTVEGCPSFVILDWEKPLNDTVTEYEV---------------ISRENGSFSGKNKSIQM 890 T C + V N +TE + ++ S K K+ + Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 891 TNQTFSTVENLKP---NTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDA 947 T T S V P TS + PK L + P + P V +P G + Sbjct: 667 T--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP-------EPKKPPPLVKQPTLHGSPS 717 Query: 948 IWTERPFNSDSYSE 961 ++P +DS S+ Sbjct: 718 AKAKQPPEADSLSK 731 Score = 60.5 bits (145), Expect = 8e-09 Identities = 102/422 (24%), Positives = 159/422 (37%), Gaps = 79/422 (18%) Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEIFT--SPEMQPTTPAPQQTTSIPSTPKRRPRP 476 P K ++QP +PS P + + + +P +P+ P+ Q + ++P+ Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759 Query: 477 KPPRTKPERTTSAGT---ITPKISKSPEPTWTTPAPGKTQFISLKPKIP-----LSPEVT 528 P T ++SA T I +S TTP P KT P +SP + Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PLKTDSAKPSQSFPPTGEKVSPFDS 818 Query: 529 HTKPAPKQTPRAPPKPKTSPRPR-IPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDV 587 P P + P S + Q PV K + A+ K SP P+ P PK Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK---PMPKGS 875 Query: 588 LLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL---EETDQSTQEPFTTKI 644 P P P Q+ P P + SP P ++ + +L TD +P T + Sbjct: 876 PTPPGPRPTAGQTVPTPQQ----------SPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925 Query: 645 PRTTEL-----AKTTQAPHRFYTTVRPRTSDKPHIRPG----VKQAPRPS------GADR 689 T +L + +QA + T +P PH + G +KQAP PS G + Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQP----GPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981 Query: 690 NV---------SVDSTHPTKKPGTRR--PPLPPRPTHPR----RKPLP---PNNVTGKPG 731 + S+ TK P + P PT R +KP P ++T +P Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041 Query: 732 SAGIISSGPITTPPLRSTPRPTGT-PLERIETDI--KQP----TVPASGEELENITDFSS 784 A + L +P+P T PL + E +I K P T ++ N+ F+ Sbjct: 1042 KA-------VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094 Query: 785 SP 786 +P Sbjct: 1095 TP 1096 Score = 55.1 bits (131), Expect = 4e-07 Identities = 83/375 (22%), Positives = 131/375 (34%), Gaps = 62/375 (16%) Query: 314 ETLALPAESKTPEVEKISAR-PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPT 372 ++L+ PA K P V + P P+ KPTT S TT KP I P+ Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT-----KPDI-PS 780 Query: 373 AKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRAT 432 +K+ Q+ + + P +D + S S+ T +++ P S+ + +P + Sbjct: 781 SKV---------QSQAEEKTTPPLKTDSAKPSQSFPPTGEKV----SPFDSKAIPRPASD 827 Query: 433 --LAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490 + P K + P + P QT P P +P PK T P +AG Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPTAG 886 Query: 491 TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT---- 546 P +SP+P + S + APK P P + T Sbjct: 887 QTVPTPQQSPKPQ--------------EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932 Query: 547 -------SPRPRIPQT--QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEV 597 S + T QP P A K +P+P T+ P Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP---------KST 983 Query: 598 SQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAP 657 Q+ PAP + IP + + +P+ E+L+ E+ + K P + T P Sbjct: 984 GQAPPAP--AKSIP-VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040 Query: 658 HRFYTTVRPRTSDKP 672 + + S KP Sbjct: 1041 QKAVLPTKLEKSPKP 1055 Score = 52.8 bits (125), Expect = 2e-06 Identities = 123/559 (22%), Positives = 188/559 (33%), Gaps = 77/559 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETV---PRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375 P +K P + SA+P + P + P+ P S T S + P+A+ Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543 Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAP 435 +K Q +T V S T S +P + + ++ + PKT L L Sbjct: 544 PSPAKP-SAQQSTKPV--SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL- 599 Query: 436 SETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP-------ERTTS 488 VP+K T E Q T++ S P P K + Sbjct: 600 ----HVPEKANFNTCTECQ---------TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646 Query: 489 AGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP 548 G + P + SP+P T AP T + V+ + P P+QT PK +P Sbjct: 647 GGDLAP-VPSSPQPKLKT-APVTT-----------TSAVSKSSPQPQQTS---PKKDAAP 690 Query: 549 RPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL---LPHKPYPEVSQSEPAPL 605 + + + P PK P + +P SP P D L P K S+ + AP+ Sbjct: 691 KQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749 Query: 606 ETRGIPFIPMISP-----SPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ----- 655 M+ P S S + + + +Q T P T+ AK +Q Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809 Query: 656 ----APHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPP 711 +P RP + K PG + G + V KK T+ P P Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPG--PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867 Query: 712 RPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI-ETDIKQPTVP 770 P+ P PP G +AG P +P + R L I + QPT P Sbjct: 868 AKPMPKGSPTPP----GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923 Query: 771 ---ASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEE 827 +G+ S + G+P GPH Q +P + + P + Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQP---GPH---SQSGPGAPMKQAPAPSQPPTSQ 977 Query: 828 ATEGNATSPPQNPPTNLTV 846 + P P ++ V Sbjct: 978 GPPKSTGQAPPAPAKSIPV 996 Score = 49.3 bits (116), Expect = 2e-05 Identities = 89/403 (22%), Positives = 135/403 (33%), Gaps = 52/403 (12%) Query: 327 VEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQT 386 V +S +++ VP+ P D T L SEK + K + + +L+ Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVA----DTVSTDLLISEKDPVKKAKKETGNGIILEVLE 2318 Query: 387 ATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPK---------TSRTLEQPR-ATLAPS 436 A D + +S++ + ++P K + T Q + A+ PS Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378 Query: 437 ETPFV---PQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT 493 +P V P K F + P P P P P PP P T+ TI Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL 2438 Query: 494 PKISKSPEPTWTTPAPG-------KTQFISLKPKIPLSPEVTHTKPAPKQTPRA------ 540 PK + TT P +T + +P++ T P P + Sbjct: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498 Query: 541 ------PPKPKTSPRPRIPQTQPVPKVPQRVTAKPK----TSPS-----PEVSYTTPAPK 585 P KP +P+P IPQ + P + KP TS Y P+P Sbjct: 2499 FTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPT 2558 Query: 586 DVLLPH--KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT----LEETDQSTQEP 639 L PH K P S+S +P P S + T+ D + EP Sbjct: 2559 SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618 Query: 640 FTTKIPRTTELAKTTQAPHRFYTTVRPRT-SDKPHIRPGVKQA 681 + +P T + + FY + +T S P P QA Sbjct: 2619 VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661 Score = 47.8 bits (112), Expect = 6e-05 Identities = 75/330 (22%), Positives = 111/330 (33%), Gaps = 56/330 (16%) Query: 292 VKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTS 351 VK L+ S K + ++ + E TP ++ SA+P+ P T + P S Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-VSPFDS 818 Query: 352 SALD--VSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTA 409 A+ S++ + S P + D + + SP +P S T Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878 Query: 410 TSDRILDSIPPKTSRTLEQPRATLAPSETP--FVPQKLEIFTSPEMQPTTPAPQQTTSI- 466 R P +T+ P+ + P E F I +P+ QPTTP T + Sbjct: 879 PGPR------PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932 Query: 467 ---------------------------PSTP-KRRPRPKPPRTKPERTTSAGTITPKISK 498 P P K+ P P P T S G P +K Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992 Query: 499 SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPV 558 S T AP + L+PK +P V T +T + PP K S + + Sbjct: 993 SIPVKKETKAPAAEK---LEPKAEQAPTVKRT-----ETEKKPPPIKDS--------KSL 1036 Query: 559 PKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588 PQ+ K SP+ T P K L Sbjct: 1037 TAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066 Score = 46.6 bits (109), Expect = 1e-04 Identities = 144/636 (22%), Positives = 236/636 (37%), Gaps = 107/636 (16%) Query: 268 SPEKAPLGGVILVHLIIPGLNETTV---KLP-ASLMFEI-SDALKTQLAKNETLALP--- 319 SP +AP+G + E+T+ ++P ASL + S A T + TL++P Sbjct: 2081 SPTQAPIG---------EDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVK 2131 Query: 320 --AESKTPEVE-KISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWI---VPTA 373 T E+E + T E + + T S S T++ S+ P + V + Sbjct: 2132 ITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSV 2191 Query: 374 KISEDSKVLQPQTATYDVFSSPTT-----SDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 ++ S + + V++ P D EIS S T I+D P + S +L++ Sbjct: 2192 CTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSS-TYFPGSIID-YPEEISVSLDR 2249 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488 + + L S ++ P P+ + + K P K ++ T Sbjct: 2250 TAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETG 2309 Query: 489 AGTITPKIS-----KSPEPTWTTPAPGKTQFI---SLKPKIPLSPEVTHTKPAPKQTPRA 540 G I + K E T + +T F S +P+ +++ T +T Sbjct: 2310 NGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET--- 2366 Query: 541 PPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT---SPSPEVSYTTPAPKDVLLPHKPYPE 596 + P ++P P V +P AKP+ S S ++S P P P P P Sbjct: 2367 --FGQEKPASQLPSGSPSVSSLP----AKPRPFFRSSSLDISAQPPPPPP---PPPPPPP 2417 Query: 597 VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP---RTTELAKT 653 P P P P SP P T L + + P TT P T L T Sbjct: 2418 PPPPPPPP------PLPPPTSPKP------TILPKKKLTVASPVTTATPLFDAVTTLETT 2465 Query: 654 TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRP 713 R T+ P + P K + PSG + TH +P +PP+ P+P Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPP--KPSSIPSG------LVFTH---RPEPSKPPIAPKP 2514 Query: 714 THPR--RKPLPPNNVTGKPGSAGIISSG------------PITTPPL-----RSTPRPTG 754 P+ P ++ KP + SS P T PL +S+PR + Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574 Query: 755 TPLER--IETDIKQPTVPASGEELENITDFS-SSPTRETDPLGKPRFKGPHVRYIQKPDN 811 + E + T +P P + IT + SP+++ + P V ++ P + Sbjct: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634 Query: 812 SPCS--ITDSVKRFPKEEATEGNATSPPQNPPTNLT 845 S + I+ +++ F AT A S Q PT++T Sbjct: 2635 SEQTFYISGALQTF---SATPVTAPSSFQAAPTSVT 2667 Score = 42.7 bits (99), Expect = 0.002 Identities = 130/646 (20%), Positives = 213/646 (32%), Gaps = 96/646 (14%) Query: 312 KNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVP 371 K + +P S TP + +A T TP+ P+ + + +L++ T A +P Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP---T 921 Query: 372 TAKISEDSKVLQPQTATYDVFS---SPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 T + + K+ + + S S P A + P TS+ + Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488 P+ +P K E +P + P +Q ++ T + KPP K ++ + Sbjct: 982 STGQAPPAPAKSIPVKKET-KAPAAEKLEPKAEQAPTVKRTETEK---KPPPIKDSKSLT 1037 Query: 489 A----GTITPKISKSPEPTWTTPAPGKTQFISLK--PKIPLSPEVTHT-------KPAPK 535 A + K+ KSP+P T P I K P E + P P Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097 Query: 536 QT--------------------------PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569 T P AP PK SP P P Q+ P Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP-----VPTESSSQKTAVPP 1152 Query: 570 --KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQ- 626 K E T A K +L + E E P PM++ QEE + Sbjct: 1153 QVKLVKKQEQEVKTEAEKVIL---EKVKETLSMEKIP---------PMVTTDQKQEESKL 1200 Query: 627 -----TTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQA 681 + L+E +E IP ++ + P +P DK + A Sbjct: 1201 EKDKASALQEKKPLPEE--KKLIPEEEKIRSEEKKP--LLEEKKPTPEDKKLLPEAKTSA 1256 Query: 682 PRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRK--PLPPNNVTGKPGSAGIISSG 739 P D S K G P P+ K LP +G P S + Sbjct: 1257 PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP----SGTPQS--LPKED 1310 Query: 740 PITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFK 799 TT ++ P+P T + D +P + +E + SS + L + Sbjct: 1311 DKTTKTIKEQPQPPCT----AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366 Query: 800 GPHVRYI--QKPDNSPCSITDSVKRFPKEE-ATEGNATSPPQNPPTNLTVVTVEGCPSFV 856 + + P P D +K K+ + E + +SP TV+++ + Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426 Query: 857 ILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLK 902 + D EK ++ T+ +S E K +S+ T + + E +K Sbjct: 1427 LAD-EK--SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK 1469 Score = 40.4 bits (93), Expect = 0.009 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 33/321 (10%) Query: 345 STKPTTSSALDVSETTLASSEKPWIVPT-----AKISE--DSKVLQPQTATYDVFSSPTT 397 S + T ++D S T + W +PT A++ + DS +T SS Sbjct: 3459 SRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAV 3518 Query: 398 SDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 EIS SI + +E + AP +T + L T + + Sbjct: 3519 QTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKT-YKGGSLGCQTEADSDTQS 3577 Query: 458 PAPQQTTSIPSTPKRRPRPKPPR---TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQF 514 P Q S S PK + RP P + R S + P KSP+ ++ +P Sbjct: 3578 P---QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP----- 3629 Query: 515 ISLKPKIPL-SPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT- 571 L P L S V + KP P +P K ++P P K+ QR + PK Sbjct: 3630 --LSPGKALESAFVPYEKPLPDDI--SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685 Query: 572 SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631 SP+ + S P K ++ S R +P +P EE+ T + Sbjct: 3686 SPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLP-------NPPPEEISTGTQS 3738 Query: 632 TDQSTQEPFTTKIPRTTELAK 652 T + +I RT +A+ Sbjct: 3739 TFSTMGTVSRRRICRTNTMAR 3759 Score = 35.8 bits (81), Expect = 0.22 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 25/152 (16%) Query: 411 SDRILDSIPP---KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP 467 SD + S P ++ +E+PR + F+P + + S + PT+P Q S P Sbjct: 3835 SDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQT-ESQLVPPTSPYTQYQYSSP 3893 Query: 468 STPKRRP-----------------RPKPPRTKPE-RTTSAGTITPKISKSPEPTWTTPAP 509 + P + P + P +T+P + + + TP++ +P P + P Sbjct: 3894 ALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLP 3953 Query: 510 GKTQFISLKPK---IPLSPEVTHTKPAPKQTP 538 + I KP+ + L P++T + P Sbjct: 3954 SQMMVIQQKPRQTTLYLEPKITSNYEVIRNQP 3985 Score = 34.3 bits (77), Expect = 0.65 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 9/82 (10%) Query: 639 PFTTKIPRTTE--LAKTTQAPHRFYTTVRPRTSDKPH--IRPGVKQAPRPSGADRNVSVD 694 P T IP E L++ ++ R V R P + P ++P R +D Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESP---SMHRKQELD 88 Query: 695 STHPTKKPGTRRPPLPPRPTHP 716 S+HP K+ G RPP P RP P Sbjct: 89 SSHPPKQSG--RPPDPGRPAQP 108 Score = 34.3 bits (77), Expect = 0.65 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 526 EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA-P 584 EV+ T+P ++ +P+T+P+ Q P P+ P TSP + Y++PA P Sbjct: 3838 EVSSTRPTRIESQHGIERPRTAPQTEFSQFIP-PQTQTESQLVPPTSPYTQYQYSSPALP 3896 Query: 585 KDVLLPHKP----------YPEVS--QSEPAPLETRGIPFIPMISPSPSQE 623 + + +VS Q++P + F P + P+P+ + Sbjct: 3897 TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ 3947 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 82.0 bits (201), Expect = 3e-15 Identities = 149/674 (22%), Positives = 228/674 (33%), Gaps = 75/674 (11%) Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378 P P + K T + + +P + T S S T L K ++P + Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG--FLSE 159 Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438 L ++ + F+ + E S T +++ K ++ P P Sbjct: 160 VNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP- 218 Query: 439 PFVPQKLEIFTSPEMQPTTP---APQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK 495 +P++ P Q TP + QQ I S P +P T+ +T A + Sbjct: 219 --IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276 Query: 496 ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTP-RAPPKPKTSPRPRIPQ 554 + P+ G+ S+KP +P + +P P + P + P K+ P P P Sbjct: 277 DASRPQTKQADIVRGE----SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332 Query: 555 TQPV----PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGI 610 QP P Q T KP P TT P L P KP + + SE E G Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPG----TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 611 PFI---PMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPR 667 + P + +P+Q+ +P T ++ LA Q P P Sbjct: 389 KALAQPPGVGKTPAQQP----------GPAKPPTQQVGTPKPLA---QQPGLQSPAKAPG 435 Query: 668 TSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 727 + P +PG + P S T PTK P P P P P PP Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ--- 492 Query: 728 GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPT-VPASGE-ELENITDFSSS 785 +PGSA S P +T P P P P + K P+ P S + + + S Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGP-AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550 Query: 786 PTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLT 845 + T P+ + P +Q P SP + + PK N T + P Sbjct: 551 AQQSTKPVSQTGSGKP----LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606 Query: 846 VVTVEGCPSFVILDWEKPLNDTVTEYEV---------------ISRENGSFSGKNKSIQM 890 T C + V N +TE + ++ S K K+ + Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666 Query: 891 TNQTFSTVENLKP---NTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDA 947 T T S V P TS + PK L + P + P V +P G + Sbjct: 667 T--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP-------EPKKPPPLVKQPTLHGSPS 717 Query: 948 IWTERPFNSDSYSE 961 ++P +DS S+ Sbjct: 718 AKAKQPPEADSLSK 731 Score = 60.5 bits (145), Expect = 8e-09 Identities = 102/422 (24%), Positives = 159/422 (37%), Gaps = 79/422 (18%) Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEIFT--SPEMQPTTPAPQQTTSIPSTPKRRPRP 476 P K ++QP +PS P + + + +P +P+ P+ Q + ++P+ Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759 Query: 477 KPPRTKPERTTSAGT---ITPKISKSPEPTWTTPAPGKTQFISLKPKIP-----LSPEVT 528 P T ++SA T I +S TTP P KT P +SP + Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PLKTDSAKPSQSFPPTGEKVSPFDS 818 Query: 529 HTKPAPKQTPRAPPKPKTSPRPR-IPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDV 587 P P + P S + Q PV K + A+ K SP P+ P PK Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK---PMPKGS 875 Query: 588 LLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL---EETDQSTQEPFTTKI 644 P P P Q+ P P + SP P ++ + +L TD +P T + Sbjct: 876 PTPPGPRPTAGQTVPTPQQ----------SPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925 Query: 645 PRTTEL-----AKTTQAPHRFYTTVRPRTSDKPHIRPG----VKQAPRPS------GADR 689 T +L + +QA + T +P PH + G +KQAP PS G + Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQP----GPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981 Query: 690 NV---------SVDSTHPTKKPGTRR--PPLPPRPTHPR----RKPLP---PNNVTGKPG 731 + S+ TK P + P PT R +KP P ++T +P Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041 Query: 732 SAGIISSGPITTPPLRSTPRPTGT-PLERIETDI--KQP----TVPASGEELENITDFSS 784 A + L +P+P T PL + E +I K P T ++ N+ F+ Sbjct: 1042 KA-------VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094 Query: 785 SP 786 +P Sbjct: 1095 TP 1096 Score = 55.1 bits (131), Expect = 4e-07 Identities = 83/375 (22%), Positives = 131/375 (34%), Gaps = 62/375 (16%) Query: 314 ETLALPAESKTPEVEKISAR-PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPT 372 ++L+ PA K P V + P P+ KPTT S TT KP I P+ Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT-----KPDI-PS 780 Query: 373 AKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRAT 432 +K+ Q+ + + P +D + S S+ T +++ P S+ + +P + Sbjct: 781 SKV---------QSQAEEKTTPPLKTDSAKPSQSFPPTGEKV----SPFDSKAIPRPASD 827 Query: 433 --LAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490 + P K + P + P QT P P +P PK T P +AG Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPTAG 886 Query: 491 TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT---- 546 P +SP+P + S + APK P P + T Sbjct: 887 QTVPTPQQSPKPQ--------------EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932 Query: 547 -------SPRPRIPQT--QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEV 597 S + T QP P A K +P+P T+ P Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP---------KST 983 Query: 598 SQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAP 657 Q+ PAP + IP + + +P+ E+L+ E+ + K P + T P Sbjct: 984 GQAPPAP--AKSIP-VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040 Query: 658 HRFYTTVRPRTSDKP 672 + + S KP Sbjct: 1041 QKAVLPTKLEKSPKP 1055 Score = 52.8 bits (125), Expect = 2e-06 Identities = 123/559 (22%), Positives = 188/559 (33%), Gaps = 77/559 (13%) Query: 319 PAESKTPEVEKISARPTTVTPETV---PRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375 P +K P + SA+P + P + P+ P S T S + P+A+ Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543 Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAP 435 +K Q +T V S T S +P + + ++ + PKT L L Sbjct: 544 PSPAKP-SAQQSTKPV--SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL- 599 Query: 436 SETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP-------ERTTS 488 VP+K T E Q T++ S P P K + Sbjct: 600 ----HVPEKANFNTCTECQ---------TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646 Query: 489 AGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP 548 G + P + SP+P T AP T + V+ + P P+QT PK +P Sbjct: 647 GGDLAP-VPSSPQPKLKT-APVTT-----------TSAVSKSSPQPQQTS---PKKDAAP 690 Query: 549 RPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL---LPHKPYPEVSQSEPAPL 605 + + + P PK P + +P SP P D L P K S+ + AP+ Sbjct: 691 KQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749 Query: 606 ETRGIPFIPMISP-----SPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ----- 655 M+ P S S + + + +Q T P T+ AK +Q Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809 Query: 656 ----APHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPP 711 +P RP + K PG + G + V KK T+ P P Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPG--PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867 Query: 712 RPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI-ETDIKQPTVP 770 P+ P PP G +AG P +P + R L I + QPT P Sbjct: 868 AKPMPKGSPTPP----GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923 Query: 771 ---ASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEE 827 +G+ S + G+P GPH Q +P + + P + Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQP---GPH---SQSGPGAPMKQAPAPSQPPTSQ 977 Query: 828 ATEGNATSPPQNPPTNLTV 846 + P P ++ V Sbjct: 978 GPPKSTGQAPPAPAKSIPV 996 Score = 49.3 bits (116), Expect = 2e-05 Identities = 89/403 (22%), Positives = 135/403 (33%), Gaps = 52/403 (12%) Query: 327 VEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQT 386 V +S +++ VP+ P D T L SEK + K + + +L+ Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVA----DTVSTDLLISEKDPVKKAKKETGNGIILEVLE 2318 Query: 387 ATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPK---------TSRTLEQPR-ATLAPS 436 A D + +S++ + ++P K + T Q + A+ PS Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378 Query: 437 ETPFV---PQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT 493 +P V P K F + P P P P P PP P T+ TI Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL 2438 Query: 494 PKISKSPEPTWTTPAPG-------KTQFISLKPKIPLSPEVTHTKPAPKQTPRA------ 540 PK + TT P +T + +P++ T P P + Sbjct: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498 Query: 541 ------PPKPKTSPRPRIPQTQPVPKVPQRVTAKPK----TSPS-----PEVSYTTPAPK 585 P KP +P+P IPQ + P + KP TS Y P+P Sbjct: 2499 FTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPT 2558 Query: 586 DVLLPH--KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT----LEETDQSTQEP 639 L PH K P S+S +P P S + T+ D + EP Sbjct: 2559 SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618 Query: 640 FTTKIPRTTELAKTTQAPHRFYTTVRPRT-SDKPHIRPGVKQA 681 + +P T + + FY + +T S P P QA Sbjct: 2619 VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661 Score = 47.8 bits (112), Expect = 6e-05 Identities = 75/330 (22%), Positives = 111/330 (33%), Gaps = 56/330 (16%) Query: 292 VKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTS 351 VK L+ S K + ++ + E TP ++ SA+P+ P T + P S Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-VSPFDS 818 Query: 352 SALD--VSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTA 409 A+ S++ + S P + D + + SP +P S T Sbjct: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878 Query: 410 TSDRILDSIPPKTSRTLEQPRATLAPSETP--FVPQKLEIFTSPEMQPTTPAPQQTTSI- 466 R P +T+ P+ + P E F I +P+ QPTTP T + Sbjct: 879 PGPR------PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932 Query: 467 ---------------------------PSTP-KRRPRPKPPRTKPERTTSAGTITPKISK 498 P P K+ P P P T S G P +K Sbjct: 933 GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992 Query: 499 SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPV 558 S T AP + L+PK +P V T +T + PP K S + + Sbjct: 993 SIPVKKETKAPAAEK---LEPKAEQAPTVKRT-----ETEKKPPPIKDS--------KSL 1036 Query: 559 PKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588 PQ+ K SP+ T P K L Sbjct: 1037 TAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066 Score = 46.6 bits (109), Expect = 1e-04 Identities = 144/636 (22%), Positives = 236/636 (37%), Gaps = 107/636 (16%) Query: 268 SPEKAPLGGVILVHLIIPGLNETTV---KLP-ASLMFEI-SDALKTQLAKNETLALP--- 319 SP +AP+G + E+T+ ++P ASL + S A T + TL++P Sbjct: 2081 SPTQAPIG---------EDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVK 2131 Query: 320 --AESKTPEVE-KISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWI---VPTA 373 T E+E + T E + + T S S T++ S+ P + V + Sbjct: 2132 ITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSV 2191 Query: 374 KISEDSKVLQPQTATYDVFSSPTT-----SDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 ++ S + + V++ P D EIS S T I+D P + S +L++ Sbjct: 2192 CTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSS-TYFPGSIID-YPEEISVSLDR 2249 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488 + + L S ++ P P+ + + K P K ++ T Sbjct: 2250 TAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETG 2309 Query: 489 AGTITPKIS-----KSPEPTWTTPAPGKTQFI---SLKPKIPLSPEVTHTKPAPKQTPRA 540 G I + K E T + +T F S +P+ +++ T +T Sbjct: 2310 NGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET--- 2366 Query: 541 PPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT---SPSPEVSYTTPAPKDVLLPHKPYPE 596 + P ++P P V +P AKP+ S S ++S P P P P P Sbjct: 2367 --FGQEKPASQLPSGSPSVSSLP----AKPRPFFRSSSLDISAQPPPPPP---PPPPPPP 2417 Query: 597 VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP---RTTELAKT 653 P P P P SP P T L + + P TT P T L T Sbjct: 2418 PPPPPPPP------PLPPPTSPKP------TILPKKKLTVASPVTTATPLFDAVTTLETT 2465 Query: 654 TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRP 713 R T+ P + P K + PSG + TH +P +PP+ P+P Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPP--KPSSIPSG------LVFTH---RPEPSKPPIAPKP 2514 Query: 714 THPR--RKPLPPNNVTGKPGSAGIISSG------------PITTPPL-----RSTPRPTG 754 P+ P ++ KP + SS P T PL +S+PR + Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574 Query: 755 TPLER--IETDIKQPTVPASGEELENITDFS-SSPTRETDPLGKPRFKGPHVRYIQKPDN 811 + E + T +P P + IT + SP+++ + P V ++ P + Sbjct: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634 Query: 812 SPCS--ITDSVKRFPKEEATEGNATSPPQNPPTNLT 845 S + I+ +++ F AT A S Q PT++T Sbjct: 2635 SEQTFYISGALQTF---SATPVTAPSSFQAAPTSVT 2667 Score = 42.7 bits (99), Expect = 0.002 Identities = 130/646 (20%), Positives = 213/646 (32%), Gaps = 96/646 (14%) Query: 312 KNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVP 371 K + +P S TP + +A T TP+ P+ + + +L++ T A +P Sbjct: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP---T 921 Query: 372 TAKISEDSKVLQPQTATYDVFS---SPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 T + + K+ + + S S P A + P TS+ + Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981 Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488 P+ +P K E +P + P +Q ++ T + KPP K ++ + Sbjct: 982 STGQAPPAPAKSIPVKKET-KAPAAEKLEPKAEQAPTVKRTETEK---KPPPIKDSKSLT 1037 Query: 489 A----GTITPKISKSPEPTWTTPAPGKTQFISLK--PKIPLSPEVTHT-------KPAPK 535 A + K+ KSP+P T P I K P E + P P Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097 Query: 536 QT--------------------------PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569 T P AP PK SP P P Q+ P Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP-----VPTESSSQKTAVPP 1152 Query: 570 --KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQ- 626 K E T A K +L + E E P PM++ QEE + Sbjct: 1153 QVKLVKKQEQEVKTEAEKVIL---EKVKETLSMEKIP---------PMVTTDQKQEESKL 1200 Query: 627 -----TTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQA 681 + L+E +E IP ++ + P +P DK + A Sbjct: 1201 EKDKASALQEKKPLPEE--KKLIPEEEKIRSEEKKP--LLEEKKPTPEDKKLLPEAKTSA 1256 Query: 682 PRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRK--PLPPNNVTGKPGSAGIISSG 739 P D S K G P P+ K LP +G P S + Sbjct: 1257 PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP----SGTPQS--LPKED 1310 Query: 740 PITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFK 799 TT ++ P+P T + D +P + +E + SS + L + Sbjct: 1311 DKTTKTIKEQPQPPCT----AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366 Query: 800 GPHVRYI--QKPDNSPCSITDSVKRFPKEE-ATEGNATSPPQNPPTNLTVVTVEGCPSFV 856 + + P P D +K K+ + E + +SP TV+++ + Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426 Query: 857 ILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLK 902 + D EK ++ T+ +S E K +S+ T + + E +K Sbjct: 1427 LAD-EK--SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK 1469 Score = 40.4 bits (93), Expect = 0.009 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 33/321 (10%) Query: 345 STKPTTSSALDVSETTLASSEKPWIVPT-----AKISE--DSKVLQPQTATYDVFSSPTT 397 S + T ++D S T + W +PT A++ + DS +T SS Sbjct: 3459 SRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAV 3518 Query: 398 SDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457 EIS SI + +E + AP +T + L T + + Sbjct: 3519 QTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKT-YKGGSLGCQTEADSDTQS 3577 Query: 458 PAPQQTTSIPSTPKRRPRPKPPR---TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQF 514 P Q S S PK + RP P + R S + P KSP+ ++ +P Sbjct: 3578 P---QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP----- 3629 Query: 515 ISLKPKIPL-SPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT- 571 L P L S V + KP P +P K ++P P K+ QR + PK Sbjct: 3630 --LSPGKALESAFVPYEKPLPDDI--SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685 Query: 572 SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631 SP+ + S P K ++ S R +P +P EE+ T + Sbjct: 3686 SPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLP-------NPPPEEISTGTQS 3738 Query: 632 TDQSTQEPFTTKIPRTTELAK 652 T + +I RT +A+ Sbjct: 3739 TFSTMGTVSRRRICRTNTMAR 3759 Score = 35.8 bits (81), Expect = 0.22 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 25/152 (16%) Query: 411 SDRILDSIPP---KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP 467 SD + S P ++ +E+PR + F+P + + S + PT+P Q S P Sbjct: 3835 SDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQT-ESQLVPPTSPYTQYQYSSP 3893 Query: 468 STPKRRP-----------------RPKPPRTKPE-RTTSAGTITPKISKSPEPTWTTPAP 509 + P + P + P +T+P + + + TP++ +P P + P Sbjct: 3894 ALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLP 3953 Query: 510 GKTQFISLKPK---IPLSPEVTHTKPAPKQTP 538 + I KP+ + L P++T + P Sbjct: 3954 SQMMVIQQKPRQTTLYLEPKITSNYEVIRNQP 3985 Score = 34.3 bits (77), Expect = 0.65 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 9/82 (10%) Query: 639 PFTTKIPRTTE--LAKTTQAPHRFYTTVRPRTSDKPH--IRPGVKQAPRPSGADRNVSVD 694 P T IP E L++ ++ R V R P + P ++P R +D Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESP---SMHRKQELD 88 Query: 695 STHPTKKPGTRRPPLPPRPTHP 716 S+HP K+ G RPP P RP P Sbjct: 89 SSHPPKQSG--RPPDPGRPAQP 108 Score = 34.3 bits (77), Expect = 0.65 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 14/111 (12%) Query: 526 EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA-P 584 EV+ T+P ++ +P+T+P+ Q P P+ P TSP + Y++PA P Sbjct: 3838 EVSSTRPTRIESQHGIERPRTAPQTEFSQFIP-PQTQTESQLVPPTSPYTQYQYSSPALP 3896 Query: 585 KDVLLPHKP----------YPEVS--QSEPAPLETRGIPFIPMISPSPSQE 623 + + +VS Q++P + F P + P+P+ + Sbjct: 3897 TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ 3947 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 80.5 bits (197), Expect = 8e-15 Identities = 114/457 (24%), Positives = 165/457 (36%), Gaps = 60/457 (13%) Query: 319 PAESKTPEVEKISARPTTVTPET-------VPRSTKPTTSSALDVSETTLASSEKPWIVP 371 P TP++ +RPT V P T + ST P+ SS + T + ++ P + Sbjct: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSS----NHTPASPTQTPLLPA 1257 Query: 372 TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRA 431 T S+ TA+ PTT+ P+ + T+ L S K + T RA Sbjct: 1258 TLTSSKP-------TASSGEPPRPTTAVTPQATSGLPPTAT--LRSTATKPTVTQATTRA 1308 Query: 432 TLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP---------PRTK 482 T A + +P + T M TPA T+ P+ PK + P PR Sbjct: 1309 T-ASTASPATTSTAQSTTRTTMTLPTPATSGTS--PTLPKSTNQELPGTTATQTTGPRPT 1365 Query: 483 PERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPP 542 P TT T P P T TT T++ + P +P TH+ P +P Sbjct: 1366 PASTTGPTTPQPGQPTRPTATETTQTRTTTEYTT-----PQTPHTTHSPPT-AGSPVPST 1419 Query: 543 KPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLP-HKPYPEVSQSE 601 P T+ T P P P+ T P P S TP+ V+ P H + + Sbjct: 1420 GPVTATSFHATTTYPTPSHPE--TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNH 1477 Query: 602 PAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFY 661 AP T P P TTL+ T + P T T A ++ + ++ Sbjct: 1478 SAPTGT---------IPPP------TTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTP 1522 Query: 662 TTVRPRTSD--KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRK 719 T++ TS P + P P+ H T + RPP PP TH Sbjct: 1523 TSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAH-TNSATSSRPP-PPFTTHSPPT 1580 Query: 720 PLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTP 756 P + TG + ++ TP T PT P Sbjct: 1581 GSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVP 1617 Score = 68.6 bits (166), Expect = 3e-11 Identities = 98/412 (23%), Positives = 141/412 (34%), Gaps = 46/412 (11%) Query: 451 PEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPG 510 P M PTTP P T +P+T R P + P TS TI S P P+ Sbjct: 1195 PCMPPTTPQPPTTPQLPTTGSR-----PTQVWPMTGTST-TIGLLSSTGPSPSSNHTPAS 1248 Query: 511 KTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK 570 TQ PL P T T P + PP+P T+ P+ P + KP Sbjct: 1249 PTQ-------TPLLP-ATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT 1300 Query: 571 TSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLE 630 + + + + A + + + P P + P +P S +QE TT Sbjct: 1301 VTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLP---KSTNQELPGTTAT 1357 Query: 631 ETDQSTQEPFTTKIPRTTELAKTTQ----APHRFYTTVRPRTSDKPHIRPGVKQAPRPSG 686 +T P +T P T + + T+ + TT T PH A P Sbjct: 1358 QTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVP 1417 Query: 687 ADRNVSVDSTHPTKKPGTRRPPLPPRPTH--PRRKPL--PPNNVTGKPGSAGIISSGPIT 742 + V+ S H T T P PTH P L P + P A + +S Sbjct: 1418 STGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNH 1477 Query: 743 TPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPH 802 + P + P PT T T P P + + + FS++ T P H Sbjct: 1478 SAPTGTIPPPT-TLKATGSTHTAPPITPTTSGTSQAHSSFSTNKT--------PTSLHSH 1528 Query: 803 VRYIQKPDNSPCSI-------TDSVKRFPKEEATEGNATSPP-----QNPPT 842 P+ +P S T + R P ++ PP +PPT Sbjct: 1529 TSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPT 1580 Score = 66.2 bits (160), Expect = 2e-10 Identities = 163/738 (22%), Positives = 238/738 (32%), Gaps = 123/738 (16%) Query: 289 ETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPT--TVTPETVPRST 346 ++T + +L + L K+ LP + T + RPT + T T P+ Sbjct: 1322 QSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTAT---QTTGPRPTPASTTGPTTPQPG 1378 Query: 347 KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDS 406 +PT +A +ETT + + P + S P TA SP S P + S Sbjct: 1379 QPTRPTA---TETTQTRTTTEYTTPQTPHTTHS----PPTA-----GSPVPSTGPVTATS 1426 Query: 407 YTATSDRILDSIPPKTSRTLEQPRAT--LAPS-ETPFVPQKLEIFTSPEMQ--PTTPAPQ 461 + AT+ S P T T P +T + PS T P ++ TS PT P Sbjct: 1427 FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP 1486 Query: 462 QTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS----------PEPTWT-----T 506 TT + P P T + T K S PE T T T Sbjct: 1487 PTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTIT 1546 Query: 507 PAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPK---------PKTSPRPRIPQTQP 557 P P T+ + + + T ++P P T +PP P T+ + T P Sbjct: 1547 PNPTSTR---TRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYP 1603 Query: 558 VPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS----------EPAPLET 607 P PQ T P P S TP+ V+ P S S P L+ Sbjct: 1604 TPSHPQ--TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKA 1661 Query: 608 RG----IPFIPMISPSPSQ---------------------EELQTTLEETDQSTQEPFTT 642 G P + + + SQ + T T T P +T Sbjct: 1662 TGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST 1721 Query: 643 KIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKP 702 P T T ++T + TS H P + S+ H + Sbjct: 1722 GTPPMTVTTSGTSQSRSSFSTAK--TSTSLHSHTSSTHHPEVTSTS-TTSITPNHTST-- 1776 Query: 703 GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-----------TPPLRSTPR 751 GTR P R P P + G+ I S+GP+T TP T Sbjct: 1777 GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTL 1836 Query: 752 PTGTP--LERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG-PHVRYIQK 808 PT P + T + + ++ S PT P + G H Sbjct: 1837 PTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMT 1896 Query: 809 PDNSPCSITDSVKRFPKEEAT---EGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLN 865 P S S + S K + ++T P+ PT+ T +T P P+ Sbjct: 1897 PTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNIT----PKHTSTGTRTPVA 1952 Query: 866 DTV--------TEYEVISRENGS--FSGKNKSIQMTNQTFSTVEN-LKPNTSYEFQVKPK 914 T T + S GS FS + QT +T P T+ V P Sbjct: 1953 HTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPF 2012 Query: 915 NPLGEGPVSNTVAFSTES 932 + P ++TV +T + Sbjct: 2013 STSLVTPSTHTVIITTHT 2030 Score = 65.9 bits (159), Expect = 2e-10 Identities = 130/592 (21%), Positives = 202/592 (34%), Gaps = 73/592 (12%) Query: 315 TLALPAESKTPEVEKISARPT-TVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTA 373 T+ P ++ I + PT T+ P T ++T +T +A ++ TT +S+ + TA Sbjct: 1630 TVITPTHAQMATSASIHSMPTGTIPPPTTLKAT-GSTHTAPTMTLTTSGTSQALSSLNTA 1688 Query: 374 K--------ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRT 425 K S T+T ++ +PT++ P ++ + + TS KTS + Sbjct: 1689 KTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTS 1748 Query: 426 L-------EQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP 478 L P T + S T P T + TT A P T P Sbjct: 1749 LHSHTSSTHHPEVT-STSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTT 1807 Query: 479 P--RTKPERTTSAGTITPKISKS-PEPTWTTPAPG-KTQFISLKPKIPLSPEVTHTKPAP 534 P T P TS T T + S P T T P T ++ + P THT+ A Sbjct: 1808 PISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIP--THTQMAT 1865 Query: 535 KQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPY 594 + + P P I T P TS SP S++T L PY Sbjct: 1866 SASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPS-SFSTAKTSTSL----PY 1920 Query: 595 PEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTE----- 649 S P T P + + ++ + T + PFTT P T Sbjct: 1921 HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS 1980 Query: 650 ----LAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS------GADRNVSVDSTHPT 699 A + Q + T P+T+ H+ P PS ++ ++ + Sbjct: 1981 TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS 2040 Query: 700 KKPGTRRPPLPPRPTHPRRKPLPPNNVTGK------------PGSAGIISSGPITTPPLR 747 GT PP + T PP VT S+ ISS + P Sbjct: 2041 TPTGTVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSS--SWLPQN 2097 Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET-------DPLGKPRFKG 800 S+ RP +P+ + T P S + + FS SP+ + P+ Sbjct: 2098 SSSRPPSSPITTQLPHLSSATTPVSTTN-QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSS 2156 Query: 801 PHV----RYIQKPDNSPCSITDSVKRFPKEEATEGNATSP--PQNPPTNLTV 846 P V ++ P +S + S T + SP P +P + T+ Sbjct: 2157 PSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208 Score = 59.7 bits (143), Expect = 1e-08 Identities = 119/524 (22%), Positives = 189/524 (36%), Gaps = 76/524 (14%) Query: 315 TLALPAESKTPEVEKISARPT-TVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTA 373 T+ +P ++ I + PT T+ P T ++T +T +A ++ TT +S+ P TA Sbjct: 1854 TVIIPTHTQMATSASIHSMPTGTIPPPTTIKATG-STHTAPPMTPTTSGTSQSPSSFSTA 1912 Query: 374 KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATL 433 K S T +V + TT+ P+ + T T + + +SR L P T Sbjct: 1913 KTSTSLPYHTSSTHHPEVTPTSTTNITPK--HTSTGTRTPVAHTTSASSSR-LPTPFTTH 1969 Query: 434 AP--SETPFV---PQKLEIFTSPEMQPTTPAPQQT--TSIPSTPKRRPRPKPP----RTK 482 +P +PF P F + PT PQ T T +P P T Sbjct: 1970 SPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTH 2029 Query: 483 PERTTSA-------GTITPKIS--------KSPEPTWTTPAPGKTQFISLKPKIPLSPEV 527 + TSA GT+ P + +P T TT +T S S + Sbjct: 2030 TQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTH-SSFSTATASSSFI 2088 Query: 528 THTKPAPKQTPRAPP-KPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKD 586 + + P+ + PP P T+ P + ++++ SPS + ++ P Sbjct: 2089 SSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSS 2148 Query: 587 VLLPHKPYPEVSQSE---PAPLETRGI-----------PFIPMISPS---PSQEELQTTL 629 P P V S AP+ + + P +S S PS TT+ Sbjct: 2149 HSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208 Query: 630 EET-DQSTQEPFTTK--IPRTTELAKTTQAPHRFYTTV----RPRTSDKPHIRPGVKQAP 682 T + PFT +P +T T + H +T+ PRT+ H P Sbjct: 2209 RATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSS-- 2266 Query: 683 RPSGADRNVSVDSTHPTK-----KPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIIS 737 S R+ S+ + PT G P P R P P + T + ++ + + Sbjct: 2267 -QSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTA 2325 Query: 738 SGPI-TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780 G + P+ S PT T P V + E+ E IT Sbjct: 2326 HGSTPASAPVSSLGTPTPT----------SPGVCSVREQQEEIT 2359 Score = 35.0 bits (79), Expect = 0.38 Identities = 60/251 (23%), Positives = 87/251 (34%), Gaps = 14/251 (5%) Query: 698 PTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISS-GPITTPPLRSTP-RPTGT 755 P P T +PP P+ +P +TG + G++SS GP +P TP PT T Sbjct: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGP--SPSSNHTPASPTQT 1252 Query: 756 PLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCS 815 PL +PT +SGE T + T P R Q + S Sbjct: 1253 PLLPATLTSSKPTA-SSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311 Query: 816 ITDSVKRFPKEEATEGNATSP-PQNPPTNLTV--VTVEGCPSFVILDWEKPLNDTVTEYE 872 + T T P P T+ T+ T + P P + Sbjct: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371 Query: 873 VISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPK--NPL-GEGPVSNTVAFS 929 + + G + T QT +T E P T + P +P+ GPV+ T +F Sbjct: 1372 PTTPQPG--QPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTAT-SFH 1428 Query: 930 TESADPRVSEP 940 + P S P Sbjct: 1429 ATTTYPTPSHP 1439 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 79.7 bits (195), Expect = 1e-14 Identities = 143/641 (22%), Positives = 222/641 (34%), Gaps = 61/641 (9%) Query: 328 EKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED-----SKVL 382 E I R T T P PT + + +E T +P +E+ ++ Sbjct: 322 EPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 381 Query: 383 QPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVP 442 + T + ++P+ ++ E + +D+ S T P A + +P P Sbjct: 382 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP 441 Query: 443 QKLEIFTSPEMQPTTPA-PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPE 501 + T+ E +PA P + + K P P T+ TT+ TP ++ E Sbjct: 442 TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEP-TENRETTANEKTTPSPAEPTE 500 Query: 502 PTWTTP-APGKTQFISLKP-----KIPLSPEVTHTKPA-PKQTPRAPPKPKTSPRPRIPQ 554 TP A KT S +P + PL+ E T PA P + KT+P P Sbjct: 501 NGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSP---- 556 Query: 555 TQPVPKVPQRVTAKPKTSPS----PEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGI 610 +P + A KT+PS E TP + P E PL Sbjct: 557 AEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP-TEHEERTPLANENT 615 Query: 611 PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-S 669 P P++ +T E T S P T+ T KTT P T R RT + Sbjct: 616 TPSP---AEPTENRERTANENTTPSPAGP--TENREMTANEKTTLFPAE-PTENRERTAN 669 Query: 670 DKPHIRPG--VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 727 +K P + R A+ + S PT+ H R PL N T Sbjct: 670 EKTTSSPAEPTENGQRTPFANEKTTSSSAEPTE--------------HGERTPLANENTT 715 Query: 728 GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPT 787 P + T ++TP P P E E + T P+ + EN + Sbjct: 716 LSPAEP---TENRERTANEKTTPFP-AEPTENRERTANENTTPSPAQPTENGDRTPLANE 771 Query: 788 RETDPLGKPRFKGPHVRYI-QKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTV 846 + T L +P G + +K +S T+ +R P N TS P P N Sbjct: 772 KTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTP---LANENTTSSPAEPTENRER 828 Query: 847 VTVEGC---PSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKP 903 E P+ + E N+ T + EN ++ N++ ++ + E + P Sbjct: 829 TANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTA-NENTTLSPAEPTEHEEMTP 887 Query: 904 NTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAG 944 + + + P P G F+ E P +EP G Sbjct: 888 LANEKTTLSPAEPTENG---ERTPFTNEKTTPSSAEPTEHG 925 Score = 71.6 bits (174), Expect = 4e-12 Identities = 162/705 (22%), Positives = 248/705 (35%), Gaps = 109/705 (15%) Query: 314 ETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALD--VSETTLASSEKPWI-- 369 ET A + +P VE R TT +T P +PT + +E T +SS +P Sbjct: 465 ETTANEKTTLSP-VEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHG 523 Query: 370 --VPTAKISEDSKVLQP---QTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSR 424 P A + +P + T + ++P+ ++ E D +++ S+ T Sbjct: 524 ERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTEN 583 Query: 425 TLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAP------------QQTTSIPSTPKR 472 P A + + P + E T + TTP+P + TT P+ P Sbjct: 584 GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTE 643 Query: 473 RPR----------PKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP--- 519 P P ERT + T + + T A KT S +P Sbjct: 644 NREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEH 703 Query: 520 --KIPLSPEVTHTKPA-PKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPE 576 + PL+ E T PA P + KT+P P P + TA T+PSP Sbjct: 704 GERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTEN------RERTANENTTPSP- 756 Query: 577 VSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFI----PMISPSPSQEELQTTL-- 629 T + L K P +++ P E + PF S P++ +T L Sbjct: 757 AQPTENGDRTPLANEKTTPSLAE----PTENGKRTPFANEKTTSSSAEPTEHAERTPLAN 812 Query: 630 EETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADR 689 E T S EP T+ T KTTQ P ++K P R A+ Sbjct: 813 ENTTSSPAEP--TENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANE 870 Query: 690 NVSVDSTHPTKKP-----GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGP---- 740 N ++ PT+ + L P + P N P SA G Sbjct: 871 NTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPL 930 Query: 741 ---ITTPPL-------------RSTPRPTGTPLERIETDIKQPTVPASGEELEN------ 778 ITTP ++TP P P E ET + + T P+S E EN Sbjct: 931 ANEITTPSRAEPTEHGERIANEKATPSPA-KPTEHGETTVNEDTTPSSAEPTENGERTPL 989 Query: 779 -ITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPP 837 + ++SPT T+ G +K SP T+ +R P A E SP Sbjct: 990 ANENTTTSPTESTE-------HGERTAN-EKTTPSPAEPTEHGERTP--SANEKTIPSPA 1039 Query: 838 QNPPTNLTVVTVEGCPSFVILDWEKPLNDTV-TEYEVISRENGSFSGKNKSIQMTNQTFS 896 + PT +T PS P+ T E ++ E + S + + + +T S Sbjct: 1040 K--PTEHEEMT----PSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPT-EHGAKTTS 1092 Query: 897 TVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPV 941 E + P+ + + + ++++ A STE D S V Sbjct: 1093 ANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANV 1137 Score = 44.3 bits (103), Expect = 6e-04 Identities = 95/441 (21%), Positives = 140/441 (31%), Gaps = 38/441 (8%) Query: 458 PAPQQTTSIPSTPKRR--PRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFI 515 PA TT S K+ P PK + TT T+T K K+ P + + Sbjct: 142 PADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPL--------EKSM 193 Query: 516 SLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSP 575 S K S T T + K + P + K + T P+ S Sbjct: 194 STLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPE----KITAASKTTYKTTGTPEESEKT 249 Query: 576 EVSYTTPAPKDVLLPHK-------PYPEVSQSEPAPLETRGIPFIPMISPS---PSQEEL 625 E S TT A +L E++QS P E G +PS P++ Sbjct: 250 EDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRE 309 Query: 626 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685 +T E T S EP + T T P ++ + P Sbjct: 310 RTANENTTLSPAEPIENR--ERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGER 367 Query: 686 GADRNVSVDSTHPT----KKPGTRRPPLPPRPT-HPRRKPLPPNNVTGKPGSAGIISSGP 740 A+ N + PT + P P PT H R P + T SA G Sbjct: 368 TANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTS--SSAESTEHGE 425 Query: 741 ITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG 800 T +T P E E + T P+ EN + +++ P+ + Sbjct: 426 RTPLANENTTPSPAEPTENRERTANENTTPSPAGPTEN-RETTANEKTTLSPVEPTENRE 484 Query: 801 PHVRYIQKPDNSPCSITDSVKR--FPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVIL 858 +K SP T++ +R F E+ T +A T L P+ Sbjct: 485 TTAN--EKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTE 542 Query: 859 DWEKPLNDTVTEYEVISRENG 879 + E+ N+ T ENG Sbjct: 543 NRERTANEKTTPSPAEPTENG 563 Score = 41.2 bits (95), Expect = 0.005 Identities = 59/265 (22%), Positives = 101/265 (38%), Gaps = 41/265 (15%) Query: 288 NETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTK 347 NE T PA +T A +T+ PA K E E+++ + T P K Sbjct: 1010 NEKTTPSPAE---PTEHGERTPSANEKTIPSPA--KPTEHEEMTP---SANENTTPSPVK 1061 Query: 348 PTTSSALDVSETTLASSEKPWIVPT------AKISEDSKVLQPQTATYDVFSSPTTSDEP 401 PT + E T ++EK + P AK + ++ + P A TTS Sbjct: 1062 PT-----EHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPND 1116 Query: 402 EISDSYT--------ATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEM 453 +I+ S ATS ++ P + + + R TLA + V +K ++ Sbjct: 1117 KITSSAAESTEHRDRATSANVITPAPAEPIKHAK--RTTLAHEKMTQVTEK----STEHP 1170 Query: 454 QPTTPAPQQTTSIPSTPK--------RRPRPKPPRTKPERTTSAGTITPKISKSPEPTWT 505 + TT ++TT P P + + P KP T+T + K+P + Sbjct: 1171 EKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTE 1230 Query: 506 TPAPGKTQFISLKPKIPLSPEVTHT 530 P ++KP + ++ + + T Sbjct: 1231 NPEKTAAVTKTIKPSVKVTGDKSLT 1255 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 77.4 bits (189), Expect = 7e-14 Identities = 154/665 (23%), Positives = 234/665 (35%), Gaps = 114/665 (17%) Query: 319 PAE--SKTPEVEKISA----RPTTVTPETVPRSTKPTTSSALDVSETTLAS--------- 363 PAE S+ EK+S P P TVP + P S+ LA Sbjct: 1013 PAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLP 1072 Query: 364 SEKPWI----------VPTAKISEDSKVLQPQTATYDVFSS-----PTTSDEPEISDSYT 408 S KP + P A +S + + P+ SS P TS PE S T Sbjct: 1073 SIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPS-T 1131 Query: 409 ATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPS 468 +T+ + P + T + + + P VP T+PE+QP+T Q TS P+ Sbjct: 1132 STAQPVTPK--PTSQATRSRTNRSSVKTPEPVVP------TAPELQPSTSTDQPVTSEPT 1183 Query: 469 TPKRRPRPKPPRTKPERTT---------SAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519 + R R K T S T P ++ P T ++ + +P Sbjct: 1184 SQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP-VTSEPTSQATRGRKNRSSVKTPEP 1242 Query: 520 KIPLSPEVTHTKPAPKQTPRAPPKPKTSPR-------------PRIPQTQPVPKVPQRVT 566 +P +PE+ + + P T R P P+ +P + VT Sbjct: 1243 VVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVT 1302 Query: 567 AKP--KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624 KP +T+ S + P+ V +P P ++S S P ++P P+ Sbjct: 1303 PKPTSRTTRSRTNMSSVKTPETV-VPTAPELQISTSTDQP-----------VTPKPTS-- 1348 Query: 625 LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRP 684 +TT T+ S+ + + +P EL +T +T +P T + P R + R Sbjct: 1349 -RTTRSRTNMSSVKNPESTVPIAPELPPST-------STEQPVTPE-PTSRATRGRKNRS 1399 Query: 685 SGADRNVSVDSTHPTKKPGTRR-PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITT 743 SG V T P +P T P+ P PT + + P + ++ + P Sbjct: 1400 SGKTPETLV-PTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPET--VVPTAPELQ 1456 Query: 744 PPLRS----TPRPTG------TPLERIET-DIKQPTVPASGEELENITDFSSSPTRETDP 792 P + TP PT T ++T + PT P +S PT T Sbjct: 1457 PSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTR 1516 Query: 793 LGKPR--FKGPHVRYIQKPDNSPCSITDS-VKRFPKEEATEGNATSPPQNPPTNLTVVTV 849 K R K P P+ P + TD V P AT G P ++ + Sbjct: 1517 GRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1576 Query: 850 EGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEF 909 E PS N VT E SR + ++ S++ T P TS + Sbjct: 1577 ELQPS-------TSRNQLVTP-EPTSRATRCRTNRS-SVKTPEPVVPTAPEPHPTTSTDQ 1627 Query: 910 QVKPK 914 V PK Sbjct: 1628 PVTPK 1632 Score = 72.0 bits (175), Expect = 3e-12 Identities = 134/537 (24%), Positives = 202/537 (37%), Gaps = 77/537 (14%) Query: 323 KTPEVEKISA---RPTTVTPETV-PRSTKPTTSSALDVSETTLASSEKPWIVPTA-KISE 377 KTPE +A RP+T T V P+ T TT S ++S + +VPTA ++ Sbjct: 1279 KTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET----VVPTAPELQI 1334 Query: 378 DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSD-RILDSIPPKTSRTLEQP------- 429 + QP T +S TT +S S I +PP TS EQP Sbjct: 1335 STSTDQPVTPKP---TSRTTRSRTNMSSVKNPESTVPIAPELPPSTST--EQPVTPEPTS 1389 Query: 430 RATLAPSETPF--VPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTT 487 RAT P+ L + T+P+++P+T Q T P++ R R K T Sbjct: 1390 RATRGRKNRSSGKTPETL-VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETV 1448 Query: 488 --SAGTITPKISK----SPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTP 538 +A + P S +PEPT + G+T S+K +P +PE+ + + Sbjct: 1449 VPTAPELQPSTSTDQPVTPEPT-SQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1507 Query: 539 RAPPKPKTSPR-------------PRIPQTQPVPKVPQRVTAKPKTSPSP-EVSYTTPAP 584 P T R P P+ QP Q VT +P + + + ++ Sbjct: 1508 SEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKT 1567 Query: 585 KDVLLPHKP--YPEVSQSE---PAPLETRGIPFIPMISPSPSQEELQTTLEETDQ--STQ 637 + ++P P P S+++ P P +R S + E + T E ST Sbjct: 1568 PESIVPIAPELQPSTSRNQLVTPEPT-SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTD 1626 Query: 638 EPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRP------------GVKQAPRPS 685 +P T K+ KT ++ + V P SD P G + S Sbjct: 1627 QPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRS 1686 Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRP-THPRRKPLPPNNVTGKPGS-AGIISSGPITT 743 R + V +T + P T P+ P P T P + G PGS A I P + Sbjct: 1687 STVRAMPVPTTPEFQSPVTTDQPISPEPITQP--SCIKRQRAAGNPGSLAAPIDHKPCSA 1744 Query: 744 P--PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRF 798 P P R R + PAS + LE T +S ++ +P G+ RF Sbjct: 1745 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLE--TPIHASQIQKVEPAGRSRF 1799 Score = 54.3 bits (129), Expect = 6e-07 Identities = 108/492 (21%), Positives = 173/492 (35%), Gaps = 101/492 (20%) Query: 483 PERTTSAGTITPKISKSPEPTWTTP-------APGKTQFISLKPKIPLSPEVTHTKPAPK 535 PE AG + P + +P P+ + +P + Q L K+P + + + + A K Sbjct: 967 PEPGVGAGDL-PGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEK 1025 Query: 536 QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYP 595 + P P +P+ P+ P ++ +P P +S P+ K + K Sbjct: 1026 VSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTV--RKTRQ 1083 Query: 596 EVSQSEP-APLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTT 654 + SQ P APL + PF P + +++T ++ + T P T+ P Sbjct: 1084 DGSQEAPEAPLSSELEPFHP-------KPKIRT--RKSSRMTPFPATSAAPE-------- 1126 Query: 655 QAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPT 714 PH +T +P T P+P ++ T+ R P P Sbjct: 1127 --PHPSTSTAQPVT-------------PKP----------TSQATRSRTNRSSVKTPEPV 1161 Query: 715 HPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQP-TVPASG 773 P L P+ T + P+T+ P R + + +K P TV + Sbjct: 1162 VPTAPELQPSTSTDQ----------PVTSEPTSQVTRG-----RKSRSSVKTPETVVPTA 1206 Query: 774 EELENITD----FSSSPTRETDPLGKPR--FKGPHVRYIQKPDNSPCSITDS-VKRFPKE 826 EL+ T +S PT + K R K P P+ P + TD V P Sbjct: 1207 LELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266 Query: 827 EATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNK 886 +AT G P + E PS ++P+ T SR N S Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPS---TSTDRPVTPKPTSRTTRSRTNMS------ 1317 Query: 887 SIQMTNQTFSTVENLKPNTSYEFQVKP----------------KNPLGEGPVSNTVAFST 930 S++ T L+ +TS + V P KNP P++ + ST Sbjct: 1318 SVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1377 Query: 931 ESADPRVSEPVS 942 + P EP S Sbjct: 1378 STEQPVTPEPTS 1389 Score = 41.2 bits (95), Expect = 0.005 Identities = 65/315 (20%), Positives = 119/315 (37%), Gaps = 32/315 (10%) Query: 288 NETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE-TVPRST 346 N ++VK P S++ I+ L+ ++N+ + S+ + R + TPE VP + Sbjct: 1561 NRSSVKTPESIV-PIAPELQPSTSRNQLVTPEPTSRATRCR--TNRSSVKTPEPVVPTAP 1617 Query: 347 KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEI--- 403 +P +++ D T +S + K ++P + + F+ S PE Sbjct: 1618 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQ 1677 Query: 404 -SDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQ 462 S T S + ++P T+ + P T + P P+ + T P A Sbjct: 1678 GGQSKTLRSSTVR-AMPVPTTPEFQSPVTT----DQPISPEPI---TQPSCIKRQRAAGN 1729 Query: 463 TTSIPSTPKRRP--RPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKT-----QFI 515 S+ + +P P P+++ R G + S + P +P +T Q Sbjct: 1730 PGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQ 1789 Query: 516 SLKPK------IPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569 ++P L P+ + ++ T +PP K R + Q + K + TA+ Sbjct: 1790 KVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAE- 1848 Query: 570 KTSPSPEVSYTTPAP 584 P E TP P Sbjct: 1849 --KPGKEEDVVTPKP 1861 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 76.6 bits (187), Expect = 1e-13 Identities = 161/687 (23%), Positives = 231/687 (33%), Gaps = 88/687 (12%) Query: 213 IFNHKTVVGSKKVNGKIQSTYDQDHTVPAYVPRKLIPITIIKQVIQNVTH-------KDS 265 + NH T G ++ G +T +T A P P T +VT K Sbjct: 152 VINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHF 211 Query: 266 AKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQ---LAKNETLALPAES 322 S + V PG TT+ S KT A ET ALP + Sbjct: 212 LDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGST 271 Query: 323 KTPEVEKISARPTTV--TPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSK 380 T +S + TT +P + R+ P +++ VSE + S +P T + + Sbjct: 272 TT---AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 328 Query: 381 ---VLQPQTATYDVFSSPTTSDEP---------------EISDSYT--------ATSDRI 414 V Q TA++ + S T+ P S YT T+ + Sbjct: 329 MPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGL 388 Query: 415 LDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTS-PEMQPTTPAPQQTTS----IPST 469 L++ P S T P TL+PS + + F S P + T+PAP TTS + +T Sbjct: 389 LEASTPVHSST-GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTT 447 Query: 470 PKRRPRPKPPRTKPERTTSAG---TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPE 526 P P +T+ G TP + SP T TTP P + S Sbjct: 448 YHSSPSSTPTTHFSASSTTLGHSEESTP-VHSSPVATATTPPPAR----SATSGHVEEST 502 Query: 527 VTHTKPAPKQTPRAPPKPKTSPRPRI------PQTQPVPKVPQRVTAKPKTSPSPEVSYT 580 H P QT P TS T P A TS + T Sbjct: 503 AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGST 562 Query: 581 TPA---PKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQ 637 + + S S P + T +P +PS +T + Sbjct: 563 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLP----AGSTPSVLVGDSTPSPISSGSM 618 Query: 638 EPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS-VDST 696 E TT +P +T ++ FY++ PR+ D H+ + + + + S ST Sbjct: 619 E--TTALPGSTTKPGLSEKSTTFYSS--PRSPDTTHLPASMTSSGVSEESTTSHSRPGST 674 Query: 697 HPTKKPG-TRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT 755 H T PG T P L T P P + T PGS S GP T S P T Sbjct: 675 HTTAFPGSTTMPGLSQESTASHSSP-GPTDTTLSPGSTTASSLGPEYT-TFHSRPGST-- 730 Query: 756 PLERIETDIKQPTVPASG--EELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---D 810 ET + ASG E + + SP P G +G + P D Sbjct: 731 -----ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKD 785 Query: 811 NSPCSITDSVKRFPKEEATEGNATSPP 837 P T + + G+ +S P Sbjct: 786 TRPAPPTTTSAFVEPSTTSHGSPSSIP 812 Score = 71.6 bits (174), Expect = 4e-12 Identities = 121/529 (22%), Positives = 191/529 (36%), Gaps = 66/529 (12%) Query: 295 PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTT--VTPETVPRSTKP--TT 350 PAS + L T E+ P+ S + AR TT + E+ P P T Sbjct: 2447 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2506 Query: 351 SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTAT 410 ++ L S TT + SEK T+ S D+ + T + V +TS S TA Sbjct: 2507 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF 2566 Query: 411 SDRILDSIPPKTSRTLEQPRATLAPSETPFVP----------QKLEIFTSPEMQPTTPAP 460 D + P SR ++ ++T +P + +SP T +P Sbjct: 2567 PD---STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2623 Query: 461 QQTTSIP-----STPKRRPRPKPPRTKPERTTSAGTI--TPKISKSPEPTWTTPAPGKTQ 513 TT++ +T P P+ TTS+G + + ++ S TT +P + Sbjct: 2624 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 2683 Query: 514 FISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK 570 L+ + P THT P+P T AP + T+ R P + P P T Sbjct: 2684 SPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYH-RSPGSTPTTHFPASSTTSGH 2742 Query: 571 TS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624 + SP+ S TTP+ + S+ P E I +P + +P E Sbjct: 2743 SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE---ITTLPGSTTTPGLSE 2799 Query: 625 LQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQAPHRFYTTVRPRTSDKPHIRPG 677 TT + +S P TT P + E + P ++TV P ++ P + Sbjct: 2800 ASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL--- 2853 Query: 678 VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSA-GII 736 ++ + +V S+ PG+ + PR T + P +P S + Sbjct: 2854 ---------SEESTTVYSS----SPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTL 2900 Query: 737 SSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSS 785 + TT L T T P T P + + E T F SS Sbjct: 2901 FTEDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 2947 Score = 65.9 bits (159), Expect = 2e-10 Identities = 148/649 (22%), Positives = 226/649 (34%), Gaps = 137/649 (21%) Query: 290 TTVKLPASL----MFEISDALKTQLAKNETLALPAESKTPEVEK-----ISARPTTVTPE 340 TT PAS+ + E S ++Q + PA + TP + + S+ P + Sbjct: 3895 TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT 3954 Query: 341 TVPRST-------KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVL--QPQTATYDV 391 PRST +PTT + S T +E T+ ++E+S P + + Sbjct: 3955 VFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDS---TTSGLTEESTAFPGSPASTQTGL 4011 Query: 392 FSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTL----EQPRATLAPSET--------- 438 ++ TT+D E S ++ ++S + P S T E + L+PS T Sbjct: 4012 PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 4071 Query: 439 --PFVPQKLEIF-TSPEMQPTTPAPQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAG 490 P + +K F TSP T +P TTS ST +P P+ TT++G Sbjct: 4072 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSG 4131 Query: 491 -TITPKISKSPE-PTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTS- 547 + P S S + T T +PG T SL + H+ P +T P TS Sbjct: 4132 LSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ----STTFHSSPGDTETTLLPDDTITSG 4187 Query: 548 -PRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLE 606 P + +T TS + TT + +P S + P+P Sbjct: 4188 LVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTT---------FQSWPSSSDTTPSPPS 4238 Query: 607 TRGIPF--------IPMISPSPSQEELQTTLEETDQSTQ--------------------- 637 T +P P +P+ TTL +++ST Sbjct: 4239 TTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSV 4298 Query: 638 ---EPF----------TTKIPRTTELAKTTQAPHRFYTTVR-PRTSDKPHIRPGVKQAPR 683 EP TT +P +T A ++ FY++ R P T+ P Sbjct: 4299 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP----------- 4347 Query: 684 PSGADRNVSVDSTHPTKKPG----------TRRPPLPPRPTHPRRKPLPPNNVTGKPGSA 733 S VS +ST +PG T P + T P + T PGS Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP-GSTDTTLSPGST 4406 Query: 734 GIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASG--EELENITDFSSSPTRETD 791 S GP +T S+P T ET + ASG E + + SP Sbjct: 4407 TASSLGPEST-TFHSSPGST-------ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 4458 Query: 792 PLGKPRFKGPHVRYIQKP---DNSPCSITDSVKRFPKEEATEGNATSPP 837 P G +G + P D +P T + + G+ +S P Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTP 4507 Score = 63.9 bits (154), Expect = 8e-10 Identities = 115/556 (20%), Positives = 187/556 (33%), Gaps = 73/556 (13%) Query: 285 PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344 P V+ P S T + T + +E T A T V P Sbjct: 1955 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 2014 Query: 345 STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404 S S+ +S ++ ++ P T +SE S + SP ++ +S Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 2074 Query: 405 DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVP------- 442 + T + R P ++ T P +T P ++T +P Sbjct: 2075 EESTTSHSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2128 Query: 443 ---QKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAGTI-- 492 + +SP T +P TT++ +T P P+ TTS+G + Sbjct: 2129 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2188 Query: 493 TPKISKSPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSPR 549 + ++ S TT +P + L+ + P THT P+P T AP + T+ Sbjct: 2189 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 2248 Query: 550 PRIPQTQPVPKVPQRVTAKPKTS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPA 603 R P + P P T + SP+ S TTP+ + S+ P Sbjct: 2249 -RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2307 Query: 604 PLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQA 656 E I +P + +P E TT + +S P TT P + E + Sbjct: 2308 STE---ITTLPGSTTTPGLSEASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRSQ 2361 Query: 657 PHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHP 716 P ++TV P ++ PG+ + + S ++T + P T P H Sbjct: 2362 PGSTHSTVSPAST----TTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHS 2417 Query: 717 RRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDI--KQPTVPASGE 774 R T ++G+ T P TG P D+ + T P+S Sbjct: 2418 RPASTHTTLFTEDSTTSGLTEES--TAFPGSPASTQTGLPATLTTADLGEESTTFPSS-- 2473 Query: 775 ELENITDFSSSPTRET 790 T + SP R T Sbjct: 2474 --SGSTGTTLSPARST 2487 Score = 61.2 bits (147), Expect = 5e-09 Identities = 128/562 (22%), Positives = 193/562 (34%), Gaps = 78/562 (13%) Query: 285 PGLNETTV---KLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPET 341 PG TT+ +S + E S + + T PA S +P ++ S T T Sbjct: 1085 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 1144 Query: 342 VPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEP 401 + P+T++A TT S P PT S + SSP S Sbjct: 1145 HTTPSPPSTATAPVEESTTYHRS--PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 1202 Query: 402 EISDSYTATSDR---ILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTP 458 S +++ TS R I P ++ P +T P + ++SP TT Sbjct: 1203 P-SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE---ASTTFYSSPRSPTTTL 1258 Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLK 518 +P TS+ + P + + A T TP +S+ +++ + G T+ Sbjct: 1259 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS-SRGSTETTVFP 1317 Query: 519 PKIPLS-----PEVTHTKPAPKQT---------------PRAPPKPKTSPRPRIPQTQPV 558 S P H++PA T A P S + +P T Sbjct: 1318 HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 1377 Query: 559 PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISP 618 + + T P +S S + L + P S+ P+ ET +P P Sbjct: 1378 ADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP--SRLSPSSTETTTLPGSP---T 1432 Query: 619 SPSQEELQTTLEETDQS---TQEPFTTKIPRTTELAKTTQA-PHRFYTTVRP---RTSD- 670 +PS E TT + +S T P TT +E + T+ + P +TT P TSD Sbjct: 1433 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDL 1492 Query: 671 -----KPHIRPGVKQAPRPSGADRNVSV--DSTHPTKKPGTRRPPLPP------------ 711 H G +A G+ S+ ST PG L P Sbjct: 1493 SQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 1552 Query: 712 RPTHPRRKPLPPNNVTGKPGSAGI------ISSGPITTPPLRSTPRPTGTPLERIETDIK 765 PTH L SAG+ S P ++ +TP P GT +E Sbjct: 1553 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD---TTPSPPGTTAAPVEVSTT 1609 Query: 766 QPTVPASGEELENITDFSSSPT 787 + P+S T FS+S T Sbjct: 1610 YHSRPSS----TPTTHFSASST 1627 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/550 (20%), Positives = 186/550 (33%), Gaps = 80/550 (14%) Query: 285 PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344 P V+ P S T + T + +E T A T V P Sbjct: 3512 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 3571 Query: 345 STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404 S S+ +S ++ ++ P T +SE S + SP ++ +S Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 3631 Query: 405 DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVP------- 442 + T + R P ++ T P +T P ++T +P Sbjct: 3632 EESTTSHSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 3685 Query: 443 ---QKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAGTI-- 492 + +S T +P TT++ +T P P+ TTS+G + Sbjct: 3686 SSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 3745 Query: 493 TPKISKSPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSPR 549 + ++ S TT +P + L+ + P THT P+P T AP + T+ Sbjct: 3746 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 3805 Query: 550 PRIPQTQPVPKVPQRVTAKPKTS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPA 603 R P + P P T + SP+ S TTP+ + S+ P Sbjct: 3806 -RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 3864 Query: 604 PLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQA 656 E I +P + +P E TT + +S P TT P + E + Sbjct: 3865 STE---ITTLPGSTTTPGLSEASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRSQ 3918 Query: 657 PHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHP 716 P ++TV P ++ P + ++ + +V S+ PG+ + PR T Sbjct: 3919 PGSTHSTVSPASTTTPGL------------SEESTTVYSS----SPGSTETTVFPRSTTT 3962 Query: 717 RRKPLPPNNVTGKPGSA-GIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEE 775 + P +P S + + TT L T T P T P + + Sbjct: 3963 SVRREEPTTFHSRPASTHTTLFTEDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADL 4020 Query: 776 LENITDFSSS 785 E T F SS Sbjct: 4021 GEESTTFPSS 4030 Score = 59.7 bits (143), Expect = 1e-08 Identities = 123/560 (21%), Positives = 186/560 (33%), Gaps = 73/560 (13%) Query: 295 PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTT--VTPETVPRSTKPTTSS 352 PAS + L T E+ P+ S + AR TT + E+ P P+++ Sbjct: 2921 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2980 Query: 353 ALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSD 412 TTL S T +SE S + D SP T+ +S+ + + Sbjct: 2981 T-----TTLPGSPT-----TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 3030 Query: 413 RILDSIPPKTSRTLEQPRATLA------PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI 466 + P ++ T P +T P+ + E SP + QQ+T+ Sbjct: 3031 Q------PGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084 Query: 467 PSTP-KRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSP 525 S+P P T A T T + S T T + P Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 3144 Query: 526 EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 585 + T P+P T AP + T+ R P + P T ++ S V + A Sbjct: 3145 SSSDTTPSPPGTTAAPVEVSTTYHSR-PSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 3203 Query: 586 DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645 L P + V EP TT + ST+ TT +P Sbjct: 3204 TALFPTRSATSVLVGEP------------------------TTSPISSGSTE---TTALP 3236 Query: 646 RTTELAKTTQAPHRFYTTVR-PRTSDKP--HIRPGVKQAPRPSGADRNVSVDSTHPTKKP 702 +T A ++ FY++ R P T+ P GV + S + STH T P Sbjct: 3237 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS----HSRPGSTHTTAFP 3292 Query: 703 GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIET 762 G+ P + + + T PGS S GP +T S P T ET Sbjct: 3293 GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPEST-TFHSGPGST-------ET 3344 Query: 763 DIKQPTVPASG--EELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---DNSPCSIT 817 + ASG E + + SP P G +G + P D +P T Sbjct: 3345 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPT 3404 Query: 818 DSVKRFPKEEATEGNATSPP 837 + + G+ +S P Sbjct: 3405 TTSAFVELSTTSHGSPSSTP 3424 Score = 59.3 bits (142), Expect = 2e-08 Identities = 91/437 (20%), Positives = 150/437 (34%), Gaps = 63/437 (14%) Query: 285 PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344 P V+ P S T + T + +E T A T V P Sbjct: 872 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 931 Query: 345 STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404 S S+ +S ++ ++ P T +SE S + SP ++ +S Sbjct: 932 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 991 Query: 405 DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVPQKLEIFT 449 + T + R P ++ T P +T P ++T +P + Sbjct: 992 EESTTSRSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT-S 1044 Query: 450 SPEMQPTTP-----------APQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAGTI- 492 P + TT +P TT++ +T P P+ TTS+G + Sbjct: 1045 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE 1104 Query: 493 -TPKISKSPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSP 548 + ++ S TT +P + L+ + P THT P+P T AP + T+ Sbjct: 1105 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 1164 Query: 549 RPRIPQTQPVPKVPQRVTAKPKTS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEP 602 R P + P P T + SP+ S TTP+ + S+ P Sbjct: 1165 H-RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 1223 Query: 603 APLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQ 655 E I +P + +P E TT + +S P TT P + E + Sbjct: 1224 GSTE---ITTLPGSTTTPGLSEASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRS 1277 Query: 656 APHRFYTTVRPRTSDKP 672 P ++TV P ++ P Sbjct: 1278 QPGSTHSTVSPASTTTP 1294 Score = 59.3 bits (142), Expect = 2e-08 Identities = 126/536 (23%), Positives = 192/536 (35%), Gaps = 72/536 (13%) Query: 268 SPEKAPLGGVI---LVHLIIPGLNETTVKLPAS----LMFEISDALKTQLAKNETLALPA 320 SP ++ G++ + P ETT LP S + E S T + PA Sbjct: 4039 SPARSTTSGLVGESTPSRLSPSSTETTT-LPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097 Query: 321 ESKTPEVEKISARPTTVTPETVPRSTKPT------TSSALDVSETTLASSEKPWIVPTAK 374 + + V + S+ T + P ST T T+S L TT SS+ + Sbjct: 4098 TTTSSGVSEESS-----TSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP 4152 Query: 375 ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434 S + L Q+ T+ SSP ++ + D T TS + S P +S T A Sbjct: 4153 GSTTASSLGQQSTTFH--SSPGDTETTLLPDD-TITSGLVEASTPTHSSTGSLHTTLTPA 4209 Query: 435 PSETPFVPQKLEIFTS-PEMQPTTPAPQQTTSIP----STPKRRPRPKPPRTKPERTTSA 489 S + + ++ F S P TTP+P TT++P +T RP P +T+ Sbjct: 4210 SSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269 Query: 490 GTI--TPKISKSPEPTWTT--PAPGKTQFISLKPKI-PLSPEVTHTKPAPKQTPRAPPKP 544 G + + SP T T P T + +P P+S T T P T A Sbjct: 4270 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 4329 Query: 545 KTS---PRPRIPQT--QPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLPH-KPYPEV 597 K++ PR P T P V+ + TS S P +TT P +P Sbjct: 4330 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTA 4389 Query: 598 SQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAP 657 S S P +T P + + S TT + ST+ TT +P T + +A Sbjct: 4390 SHSSPGSTDT---TLSPGSTTASSLGPESTTFHSSPGSTE---TTLLPDNTTASGLLEA- 4442 Query: 658 HRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPT--- 714 +T ++ PH P+G+ +T + P PP T Sbjct: 4443 ----STPVHSSTGSPH------TTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492 Query: 715 -------HPRRKPLPPNNVT------GKPGSAGIISSGPITTPPLRSTPRPTGTPL 757 H P + + G+ + + S P+ T S R T + L Sbjct: 4493 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 4548 Score = 58.5 bits (140), Expect = 3e-08 Identities = 131/563 (23%), Positives = 191/563 (33%), Gaps = 87/563 (15%) Query: 339 PETVPRSTKPTTSSALDVSETTLASSEK----------------PWIVPTAKISEDSKVL 382 P T P S+ T ++AL S TT SEK P ++ +SE+S Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 4362 Query: 383 QPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVP 442 + + + P+++ P +S TA+ S P T TL P +T A S P Sbjct: 4363 HSRPGSMHTTAFPSSTTMPGVSQESTAS-----HSSPGSTDTTL-SPGSTTASS---LGP 4413 Query: 443 QKLEIFTSPEMQPTTPAPQQTTSI----PSTPKRRPRPKPPRT-KPERTTSAGTITPKIS 497 + +SP TT P TT+ STP P T P +T+ + Sbjct: 4414 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 4473 Query: 498 KSPEPTWTTPAPGKT--QFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQT 555 P TTPAP T F+ L T + +P TP ++ R ++ Sbjct: 4474 SWPNSKDTTPAPPTTTSAFVELS---------TTSHGSPSSTPTTHFSASSTTLGRSEES 4524 Query: 556 QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH-KPYPEVSQSEPAPLETRGIPFIP 614 V P T+PSP S T+ ++ H P + P T G Sbjct: 4525 TTVHSSP----VATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEES 4580 Query: 615 MISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHI 674 S S + + + T +EP T + TT P T+ R S H Sbjct: 4581 TTSHSSTTHTISSAPSTTSALVEEP--TSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 4638 Query: 675 ---RPGVKQAPRPSGADRNVSVDSTHP--------TKKPG-TRRPPLPPRPT--HPRRKP 720 G P S + +T P T PG T P L + T H Sbjct: 4639 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSS 4698 Query: 721 LPPNNVT------GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQ-------- 766 P + + G+ + + S P+ T S R T + L T Sbjct: 4699 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 4758 Query: 767 ---PTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRF 823 + ASG E+ T SS+ + P P V +SP SI + F Sbjct: 4759 HFPESSTASGRSEESRTSHSSTTHTISSP---PSTTSALVEEPTSYHSSPGSI--ATTHF 4813 Query: 824 PKEEATEG---NATSPPQNPPTN 843 P+ T G +T+ +P TN Sbjct: 4814 PESSTTSGRSEESTASHSSPDTN 4836 Score = 57.0 bits (136), Expect = 9e-08 Identities = 144/680 (21%), Positives = 225/680 (33%), Gaps = 103/680 (15%) Query: 311 AKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIV 370 + ET LP TP + + S T +P + + P T+++ VSE + S +P Sbjct: 1420 SSTETTTLPGSPTTPSLSEKSTTFYT-SPRSPDATLSPATTTSSGVSEESSTSHSQPGST 1478 Query: 371 PTAKISEDSKVLQPQTATYDVFSSPTTSD------------------------------- 399 T + T T D+ PTTS Sbjct: 1479 HTTAFPDS-------TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 1531 Query: 400 ---EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTS-PEMQP 455 E + T TS + S P +S T A S + + ++ F S P Sbjct: 1532 GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD 1591 Query: 456 TTPAPQQTTSIP----STPKRRPRPKPPRTKPERTTSAGTI--TPKISKSPEPTWTT--P 507 TTP+P TT+ P +T RP P +T+ G + + SP T T P Sbjct: 1592 TTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 1651 Query: 508 APGKTQFISLKPKI-PLSPEVTHTKPAPKQTPRAPPKPKTS---PRPRIPQT--QPVPKV 561 T + +P P+S T T P T A K++ PR P T P Sbjct: 1652 TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 1711 Query: 562 PQRVTAKPKTSPS-PEVSYTTPAPKDVLLPH-KPYPEVSQSEPAPLETRGIPFIPMISPS 619 V+ + TS S P ++TT P +P S S P +T P + + Sbjct: 1712 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT---TLSPGSTTA 1768 Query: 620 PSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679 S TT + ST+ TT +P T + +A +T ++ PH Sbjct: 1769 SSLGPESTTFHSSPGSTE---TTLLPDNTTASGLLEA-----STPVHSSTGSPH------ 1814 Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739 P+G+ +T + P PP T + ++ G P S Sbjct: 1815 TTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH--GSPSSTPTTHFS 1872 Query: 740 PITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFK 799 +T RS T P + +E T + SSP Sbjct: 1873 ASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP------------- 1919 Query: 800 GPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILD 859 + + P++S S +E T ++T+ + P + T VE S+ Sbjct: 1920 -GSTQTMHFPESSTASGRS------EESRTSHSSTTHTISSPPSTTSALVEEPTSY---- 1968 Query: 860 WEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGE 919 P + T + S +G S + T + V + TS +P+ Sbjct: 1969 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 2028 Query: 920 GPVSNTVAFSTESADPRVSE 939 G + T A + P +SE Sbjct: 2029 GSM-ETTALPGSTTTPGLSE 2047 Score = 55.5 bits (132), Expect = 3e-07 Identities = 88/402 (21%), Positives = 140/402 (34%), Gaps = 31/402 (7%) Query: 285 PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344 PG V++ + S T + + T +E T A T + P Sbjct: 1597 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT 1656 Query: 345 ST---KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEP 401 S +PTTS +S + ++ P TA +SE S + D SP ++ Sbjct: 1657 SVLVGEPTTSP---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 1713 Query: 402 EISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQ 461 +S+ T + R P ++ T P +T P + + +SP TT +P Sbjct: 1714 GVSEESTTSHSR------PGSTHTTAFPGSTTMPGVS---QESTASHSSPGSTDTTLSPG 1764 Query: 462 QTTSIPSTPKRRPRPKPPRTK-----PERTTSAGTI---TPKISKSPEPTWTTPAPGKTQ 513 TT+ P+ P + P+ TT++G + TP S + P T G T Sbjct: 1765 STTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 1824 Query: 514 FISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTS- 572 P T PAP T A + T+ P + P T ++ Sbjct: 1825 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS-PSSTPTTHFSASSTTLGRSEE 1883 Query: 573 -----PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT 627 SP + TTP+P E + +P T+ + F + S EE +T Sbjct: 1884 STTVHSSPVATATTPSPARSTTSGL-VEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942 Query: 628 TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTS 669 + T + P +T E +P TT P +S Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSS 1984 Score = 54.7 bits (130), Expect = 5e-07 Identities = 113/500 (22%), Positives = 170/500 (34%), Gaps = 39/500 (7%) Query: 301 EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSE-- 358 E S A +T+ P S T + SA T T +S+ P+T++AL + Sbjct: 499 EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT--KSSTPSTTAALAHTSYH 556 Query: 359 TTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSI 418 ++L S+E ++ IS S+ + ++ D + T+ P S D I Sbjct: 557 SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA---TTVLPAGSTPSVLVGDSTPSPI 613 Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRR 473 + T P +T P + + ++SP TT P TS +T R Sbjct: 614 SSGSMETTALPGSTTKPGLSE---KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 670 Query: 474 PRPKPPRTKPERTTSAGTITPKISK--SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTK 531 P P TT G + SP PT TT +PG T SL P+ H++ Sbjct: 671 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY----TTFHSR 726 Query: 532 PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH 591 P +T P T+ + + PV T P T+ SP S T Sbjct: 727 PGSTETTLLP--DNTTASGLLEASMPV----HSSTRSPHTTLSPAGSTTRQGESTTF--- 777 Query: 592 KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT---LEETDQSTQEPFTT--KIPR 646 +P + PAP T P + S + TT T E TT P Sbjct: 778 HSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG 837 Query: 647 TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706 +T+ T P T+ R S H + PS V +++ + T Sbjct: 838 STQ---TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 894 Query: 707 PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQ 766 P T R + + + + I+ TT L + +ET Sbjct: 895 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 954 Query: 767 PTVPASGEELENITDFSSSP 786 + G E T F SSP Sbjct: 955 GSTTTPGLS-ERSTTFHSSP 973 Score = 53.1 bits (126), Expect = 1e-06 Identities = 106/485 (21%), Positives = 162/485 (33%), Gaps = 35/485 (7%) Query: 339 PETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTS 398 P T P S+ T ++AL S TT SEK ++ S D+ + T + V TTS Sbjct: 3220 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 3279 Query: 399 DEPEISDSYTA-TSDRILDSIPPKTSRTLEQPRA---TLAPSET---PFVPQKLEIFTSP 451 S TA + + +++ + P + TL+P T P+ + P Sbjct: 3280 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGP 3339 Query: 452 EMQPTTPAPQQTTSI----PSTPKRRPRPKPPRT-KPERTTSAGTITPKISKSPEPTWTT 506 TT P TT+ STP P T P +T+ + P TT Sbjct: 3340 GSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTT 3399 Query: 507 PAPGKT--QFISLKPK---IPLSPEVTHTKPAPKQTPR---------APPKPKTSPRPRI 552 PAP T F+ L P S TH + R +P T+P P Sbjct: 3400 PAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR 3459 Query: 553 PQTQPVPKVPQRVTAKP---KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609 T + + + P +T PE T+ ++ H S AP T Sbjct: 3460 STTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS--APSTTSA 3517 Query: 610 IPFIP-MISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT 668 + P SP + + S + +T + + T P R T+V Sbjct: 3518 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 3577 Query: 669 SDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT- 727 S I G + G+ + T R P P + + T Sbjct: 3578 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 3637 Query: 728 -GKPGSAGIIS-SGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSS 785 +PGS + TTP L + + +T + + SG E+ T SSS Sbjct: 3638 HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSS 3697 Query: 786 PTRET 790 + +T Sbjct: 3698 GSTDT 3702 Score = 45.8 bits (107), Expect = 2e-04 Identities = 102/462 (22%), Positives = 156/462 (33%), Gaps = 99/462 (21%) Query: 282 LIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKIS--------AR 333 +++P + T+V L S IS ET ALP + TP + + S + Sbjct: 4646 IVLPARSTTSVLLGESTTSPISSG------SMETTALPGSTTTPGLSEKSTTFHSSPSST 4699 Query: 334 PTT----------------------VTPETVPRSTKPTTSSALDVSETTLAS--SEKPWI 369 PTT V T P + TTS ++ S +S S + Sbjct: 4700 PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 4759 Query: 370 VPTAKI----SEDSKVLQPQTATYDVFSSP-TTSDEPEISDSYTATSDRILDSIPPKTSR 424 P + SE+S+ T T+ + S P TTS E SY ++ I + P++S Sbjct: 4760 FPESSTASGRSEESRTSHSST-THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESST 4818 Query: 425 TLEQPRATLAPSETP----------------FVPQKLEIFTSPEMQPTTPAPQQTTSIPS 468 T + + A +P + + + SP TT A TT P Sbjct: 4819 TSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT--PG 4876 Query: 469 TPKRRPRPKPPRTKPERTTSAGTIT-PKISKSP-------EPTWTTPAPGKTQFISLKPK 520 + P++T S ++T IS P E T TT P T L + Sbjct: 4877 LSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQE 4936 Query: 521 IPLSPEVTHTKPAPKQTPRAPPKPKTSPRPR---IPQTQP---VPKVPQRVTAKPKTSPS 574 H+KP +T +P TS + P +QP + V T P S Sbjct: 4937 ----STTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992 Query: 575 PEVSYTTP-APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETD 633 Y++P + + H + + P SP + L TL TD Sbjct: 4993 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPD---------SPGFTHTVLPATLTTTD 5043 Query: 634 ---------QSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666 S+ TT +P + + P FY + P Sbjct: 5044 IGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSP 5085 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 75.5 bits (184), Expect = 3e-13 Identities = 160/687 (23%), Positives = 231/687 (33%), Gaps = 88/687 (12%) Query: 213 IFNHKTVVGSKKVNGKIQSTYDQDHTVPAYVPRKLIPITIIKQVIQNVTH-------KDS 265 + NH T G ++ G +T +T A P P T +VT K Sbjct: 73 VINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHF 132 Query: 266 AKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQ---LAKNETLALPAES 322 S + V PG TT+ S KT A ET ALP + Sbjct: 133 LDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGST 192 Query: 323 KTPEVEKISARPTTV--TPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSK 380 T +S + TT +P + R+ P +++ VSE + S +P T + + Sbjct: 193 TT---AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 249 Query: 381 ---VLQPQTATYDVFSSPTTSDEP---------------EISDSYT--------ATSDRI 414 V Q TA++ + S T+ P S YT T+ + Sbjct: 250 MPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGL 309 Query: 415 LDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTS-PEMQPTTPAPQQTTS----IPST 469 L++ P S T P TL+P+ + + F S P + T+PAP TTS + +T Sbjct: 310 LEASTPVHSST-GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTT 368 Query: 470 PKRRPRPKPPRTKPERTTSAG---TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPE 526 P P +T+ G TP + SP T TTP P + S Sbjct: 369 YHSSPSSTPTTHFSASSTTLGHSEESTP-VHSSPVATATTPPPAR----SATSGHVEEST 423 Query: 527 VTHTKPAPKQTPRAPPKPKTSPRPRI------PQTQPVPKVPQRVTAKPKTSPSPEVSYT 580 H P QT P TS T P A TS + T Sbjct: 424 AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGST 483 Query: 581 TPA---PKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQ 637 + + S S P + T +P +PS +T + Sbjct: 484 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLP----AGSTPSVLVGDSTPSPISSGSM 539 Query: 638 EPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS-VDST 696 E TT +P +T ++ FY++ PR+ D H+ + + + + S ST Sbjct: 540 E--TTALPGSTTKPGLSEKSTTFYSS--PRSPDTTHLPASMTSSGVSEESTTSHSRPGST 595 Query: 697 HPTKKPG-TRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT 755 H T PG T P L T P P + T PGS S GP T S P T Sbjct: 596 HTTAFPGSTTMPGLSQESTASHSSP-GPTDTTLSPGSTTASSLGPEYT-TFHSRPGST-- 651 Query: 756 PLERIETDIKQPTVPASG--EELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---D 810 ET + ASG E + + SP P G +G + P D Sbjct: 652 -----ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSND 706 Query: 811 NSPCSITDSVKRFPKEEATEGNATSPP 837 P T + + G+ +S P Sbjct: 707 TRPAPPTTTSAFVEPSTTSHGSPSSIP 733 Score = 61.6 bits (148), Expect = 4e-09 Identities = 101/494 (20%), Positives = 161/494 (32%), Gaps = 65/494 (13%) Query: 285 PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344 P V+ P S T + T + +E A T V P Sbjct: 793 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTN 852 Query: 345 STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404 S S+ +S ++ ++ P T +SE S + SP ++ +S Sbjct: 853 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 912 Query: 405 DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVPQK--LEI 447 + T + R P ++ T P +T P ++T +P + Sbjct: 913 EESTTSHSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXL 966 Query: 448 FTSPEMQPTTPAPQQTTSIP------------STPKRRPRPKPPRTKPERTTSAGTITPK 495 P P + +TT++P +T PR P TTS+G Sbjct: 967 VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1026 Query: 496 ISKSPEP--TWTTPAPGKTQFISLKPKIPL---SPEVTHTKPAPKQTPRAPPKPKTSPRP 550 + P T TT PG T + + SP T T +P+ T + P+++ Sbjct: 1027 TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFH 1086 Query: 551 RIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLP------------HKPYPEVS 598 P + +P TA S V +T +P+ L P + +P Sbjct: 1087 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSK 1146 Query: 599 QSEPAPLETRGIPFIPMISPS-PSQEELQTTLEETDQST--QEPFTTKIPRTTELAKTTQ 655 + PAP T F+ + + S S + TT +T + +T + + TT Sbjct: 1147 DTMPAPPTTTS-AFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTP 1205 Query: 656 APHRFYTTVRPRTSDKPHIRPGVKQA---PRPSGA------DRNVSVDSTHPTKKPGTRR 706 +P R T+ S H PG Q P S A R +TH P + Sbjct: 1206 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 1265 Query: 707 PPLPPRPTHPRRKP 720 L PT P Sbjct: 1266 SALVEEPTSYHSSP 1279 Score = 58.5 bits (140), Expect = 3e-08 Identities = 120/510 (23%), Positives = 176/510 (34%), Gaps = 96/510 (18%) Query: 314 ETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEK------- 366 +T LPA + T V + P T P S+ T ++AL S TT SEK Sbjct: 954 DTTLLPASTTTXLVGE---------PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1004 Query: 367 ---------PWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDS 417 P ++ +SE+S + + + P ++ P +S TA+ S Sbjct: 1005 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTAS-----HS 1059 Query: 418 IPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI----PSTPKRR 473 P T TL PR+T A S P+ + P TT P TT+ STP Sbjct: 1060 SPGSTDTTL-SPRSTTASS---LGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 1115 Query: 474 PRPKPPRT-KPERTTSAGTITPKISKSPEPTWTTPAPGKT--QFISLKPKIPLSPEVTHT 530 P T P +T+ + P T PAP T F+ L T + Sbjct: 1116 STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS---------TTS 1166 Query: 531 KPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLP 590 +P P ++ R ++ V P P T+PSP S T+ ++ Sbjct: 1167 HGSPSSIPTTHFSASSTTFGRSEESTTVHSSP----VAPATTPSPARSTTSGLVEESTAY 1222 Query: 591 HKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTEL 650 H +P T+ + F + S EE +T+ T + P +T E Sbjct: 1223 HS----------SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP 1272 Query: 651 AKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP 710 +P TT P +S SG S +ST P T + Sbjct: 1273 TSYHSSPGSIATTHFPESS-------------TTSGR----SEESTASHSSPDTN--GIT 1313 Query: 711 PRPTHPRRKPLPPNNVTG--KPGSAGIISSGPITTPPLRS----------TPRPTGTPLE 758 P P H + T PGS + TTP L + +P T +P Sbjct: 1314 PLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPAS 1373 Query: 759 RIETDIK-QPTVPASGEELENITDFSSSPT 787 + I +PT S E + T F +S T Sbjct: 1374 MTSSSISGEPTSLYSQAESTHTTAFPASTT 1403 Score = 56.2 bits (134), Expect = 2e-07 Identities = 141/667 (21%), Positives = 220/667 (32%), Gaps = 46/667 (6%) Query: 301 EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSE-- 358 E S A +T+ P S T + SA T T +S+ P+T++AL + Sbjct: 420 EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT--KSSTPSTTAALAHTSYH 477 Query: 359 TTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSI 418 ++L S+E ++ IS S+ + ++ D + T+ P S D I Sbjct: 478 SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA---TTVLPAGSTPSVLVGDSTPSPI 534 Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRR 473 + T P +T P + + ++SP TT P TS +T R Sbjct: 535 SSGSMETTALPGSTTKPGLSE---KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 591 Query: 474 PRPKPPRTKPERTTSAGTITPKISK--SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTK 531 P P TT G + SP PT TT +PG T SL P+ H++ Sbjct: 592 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY----TTFHSR 647 Query: 532 PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH 591 P +T P T+ + + PV T P T+ SP S T Sbjct: 648 PGSTETTLLP--DNTTASGLLEASMPV----HSSTRSPHTTLSPAGSTTRQGESTTF--- 698 Query: 592 KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT---LEETDQSTQEPFTT--KIPR 646 +P + + PAP T P + S + TT T E TT P Sbjct: 699 HSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG 758 Query: 647 TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706 +T+ T P T+ R S H + PS V +++ + T Sbjct: 759 STQ---TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 815 Query: 707 PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQ 766 P T R + + + + I+ T L + +ET Sbjct: 816 THFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALP 875 Query: 767 PTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKE 826 + G E T F SSP L V +S T + FP Sbjct: 876 GSTTTPGLS-ERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTT-AFPDS 933 Query: 827 EATEG----NATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFS 882 T G + TS T+ T++ V P++ TE + + Sbjct: 934 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAG 993 Query: 883 GKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG--PVSNTVAFSTESADPRVSEP 940 KS + S L P ++ V ++ ++T AF + P VS+ Sbjct: 994 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQE 1053 Query: 941 VSAGRDA 947 +A + Sbjct: 1054 STASHSS 1060 Score = 46.2 bits (108), Expect = 2e-04 Identities = 86/386 (22%), Positives = 133/386 (34%), Gaps = 63/386 (16%) Query: 328 EKISARPTTVTPETVPRSTKPTTSSALDVSETTLAS--SEKPWIVPTAKI----SEDSKV 381 E + + V P T P + TTS ++ S +S S + P + SE+S+ Sbjct: 1190 ESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1249 Query: 382 LQPQTATYDVFSSP-TTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETP- 439 T T+ + S P TTS E SY ++ I + P++S T + + A +P Sbjct: 1250 SHSST-THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPD 1308 Query: 440 ---------------FVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE 484 + + + SP TT A TT P + P+ Sbjct: 1309 TNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT--PGLSAKSTILYSSSRSPD 1366 Query: 485 RTTSAGTIT-PKISKSP-------EPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQ 536 +T S ++T IS P E T TT P T L + H+KP + Sbjct: 1367 QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQE----STTFHSKPGSTE 1422 Query: 537 TPRAPPKPKTSPRPR---IPQTQP---VPKVPQRVTAKPKTSPSPEVSYTTP-APKDVLL 589 T +P TS + P +QP + V T P S Y++P + + Sbjct: 1423 TTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAF 1482 Query: 590 PHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETD---------QSTQEPF 640 H + + P SP + L TL TD S+ Sbjct: 1483 SHSNTMSIHSQQSTPFPD---------SPGFTHTVLPATLTTTDIGQESTAFHSSSDATG 1533 Query: 641 TTKIPRTTELAKTTQAPHRFYTTVRP 666 TT +P + + P FY + P Sbjct: 1534 TTPLPARSTASDLVGEPTTFYISPSP 1559 >gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] Length = 669 Score = 75.5 bits (184), Expect = 3e-13 Identities = 136/594 (22%), Positives = 215/594 (36%), Gaps = 118/594 (19%) Query: 307 KTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEK 366 K Q ++ E LP + PE K+ E ++ P A S K Sbjct: 21 KFQASQPEPSDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFG----------AVSLK 70 Query: 367 PWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRT- 425 P P ++++ K P T P PE++D + +P K S+ Sbjct: 71 P---PPPEVTDLPKKPPPPEVT----DLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLE 123 Query: 426 ---LEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTK 482 L + L + P P + E+ +P ++ + P P P P P P ++ Sbjct: 124 LSDLSKKFPQLGATPFPRKPLQPEVGEAP-LKASLPEPGAPARKPLQPDELSHPARPPSE 182 Query: 483 PERTT--------SAGTITPKISKSPEPTWTT--PAPGKTQFISLKPKIPLSPEVTHTKP 532 P+ AG TP+ SP+P +T P + +F ++ PK P P+V Sbjct: 183 PKSGAFPRKLWQPEAGEATPR---SPQPELSTFPKKPAQPEF-NVYPKKPPQPQVGGL-- 236 Query: 533 APKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR-VTAKPKTSPSPEVSYTTPAPKDVLL-- 589 PK ++ P+P+ S + P +P P+R +A PK + P +S P L Sbjct: 237 -PK---KSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGD 292 Query: 590 ----PHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645 +P V P P E + + S P Q EL +++ EP +P Sbjct: 293 LTRTSSEPEVSVLPKRPRPAEFKAL------SKKPPQPELGGL----PRTSSEPEFNSLP 342 Query: 646 RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGV-----KQAPRPSGADRN------VSVD 694 R L + P R ++ P K H +P ++ P PS A + Sbjct: 343 RKL-LQPERRGPPRKFSQPEPSAVLKRHPQPEFFGDLPRKPPLPSSASESSLPAAVAGFS 401 Query: 695 STHPTKK-----------------PGTRRPPLPPRPTHP-RRKPLPPNNVTGKPGSAGII 736 S HP G RP L RP+HP RR+PLPP + G P + + Sbjct: 402 SRHPLSPGFGAAGTPRWRSGGLVHSGGARPGL--RPSHPPRRRPLPPASSLGHPPAKPPL 459 Query: 737 SSGPITTPPLRSTPRPTGTPLERIET---------DIKQPTVPASGEELENITDFSSSPT 787 GP+ ++S RP+ ++ T D + +P E E D P Sbjct: 460 PPGPV---DMQSFRRPSAASIDLRRTRSAAGLHFQDRQPEDIPVPDEIYELYDDV--EPR 514 Query: 788 RETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPP 841 ++ P K R + P S+ + +R P++ A PQ P Sbjct: 515 DDSSPSPKGRDEAP-------------SVQQAARRPPQDPALRKEKDPQPQQLP 555 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 74.7 bits (182), Expect = 4e-13 Identities = 114/487 (23%), Positives = 172/487 (35%), Gaps = 80/487 (16%) Query: 309 QLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368 +++ ET+A ++ P+ +SA T P + P + + T + P Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL---PR 182 Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428 P+A+ P+ T S +++ E ++ A R P L++ Sbjct: 183 PAPSAR---------PRPPTEGPRKSVSSASEHSTTEPSPAARRR------PSAGGGLQR 227 Query: 429 PRA-TLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPK------PPRT 481 P + +L+ S TP +SP + P+ + T P+ P + P+PK PP+ Sbjct: 228 PASRSLSSSATPL--------SSPAR--SGPSARGTPRAPAHPSQ-PKPKGLQALRPPQV 276 Query: 482 KPERTTSAGTITPKISK---SPEPTWTTPAPGKTQFISLKPKIPLSP------------- 525 P R +A + P S +P P+ P+P + P P +P Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPS-APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335 Query: 526 EVTHT-KPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSP--------- 575 + TH+ P+P +P A P P+ P +P Q P P P +PSP Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395 Query: 576 --EVSYTTPAPKDVLLPHKP--YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631 + ++ P V P P P VS S P + P + PS Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455 Query: 632 TDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691 Q P P QAP T P PG QAP A + Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG--QAPFSPSASLPM 513 Query: 692 SVDSTHPTKKPGTRRPPL---PPRP------THPRRKPLP-PNNVTGKPGSAGIISSGPI 741 S +T P + P PL PP P PRR P P P+ P ++ GP Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP- 572 Query: 742 TTPPLRS 748 PP RS Sbjct: 573 PPPPSRS 579 Score = 66.2 bits (160), Expect = 2e-10 Identities = 107/448 (23%), Positives = 151/448 (33%), Gaps = 43/448 (9%) Query: 419 PPKTSRTLEQPRATLAPSETPFV-PQKLEIFTSPEMQPTTPAPQQTTSI--PSTPKRRPR 475 P + L PR +P P V P L + + P ++ I + P+ PR Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 476 PKPPRT-------KPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVT 528 P RT + ER A +P SP T PG L+ +S E T Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR----ISAEET 132 Query: 529 HTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588 A + AP + S R + P P P A+ + EV PAP Sbjct: 133 ---VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189 Query: 589 LPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE-------LQTTLEETDQSTQEPFT 641 P P S S + T PSP+ LQ + S+ P + Sbjct: 190 RPPTEGPRKSVSSASEHSTT--------EPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241 Query: 642 TKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKK 701 + T +AP +P+ +RP PR A + S+ P Sbjct: 242 SPARSGPSARGTPRAPAH---PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS-PLAT 297 Query: 702 PGTRRPPLPPRP----THPRRKPLPPNNVTGKPGSAGIISSGP-ITTPPLR--STPRPTG 754 P PP P P T P PP+ T GS + ++ + +PPL +TP P Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357 Query: 755 TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPC 814 P + P+ PAS T +P L + F P +Q P + P Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 Query: 815 SITDSVKRFPKEEATEGNATSPPQNPPT 842 S S P +A A P Q PP+ Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPS 445 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 72.4 bits (176), Expect = 2e-12 Identities = 112/520 (21%), Positives = 172/520 (33%), Gaps = 49/520 (9%) Query: 261 THKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNE------ 314 T KD+ + +P G + + P E T + A + F D L + E Sbjct: 842 TVKDALDAALPSPEEGTSIAAVPAP---EGTAVVAALVPFPHEDILVASIVSLEEEDVTA 898 Query: 315 -TLALPAESKTPEVE-KISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKP-W--I 369 ++ P + P V + V + P T P ++A+ + + P W + Sbjct: 899 AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAAL 958 Query: 370 VPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQP 429 T I+E+ + +P +EP+ + +T + + P T E+P Sbjct: 959 AITVPITEEDGTPEGPVTPATTVHAP---EEPDTAAVRVSTPEE--PASPAAAVPTPEEP 1013 Query: 430 RATLAPSETPFVPQKLEIFTSPEMQPTTPA-----PQQTTSIPS---TPKRRPRPKPPRT 481 + A TP P P +PT+PA P++ TS + TP+ P Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1073 Query: 482 KPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAP 541 PE TS P + P P P + P P + T +PA Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-------PTSPAAAVPTPEEPASPAAAVPT 1126 Query: 542 PKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSE 601 P+ SP +P T P P P+ S S V+ TP P P S S Sbjct: 1127 PEEPASPAAAVP-TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASF 1185 Query: 602 PAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFY 661 A + T P P S P+ + TLEE +P + E A A Sbjct: 1186 AAVVATLEEPTSPAAS-VPTPAAMVATLEEFTSP-----AASVPTSEEPASLAAA----- 1234 Query: 662 TTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKK-PGTRRPPLPPRPTHPRRKP 720 P P + P S A + + P P P P +P Sbjct: 1235 -VSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293 Query: 721 LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI 760 P P A I + + TP + + P P+E + Sbjct: 1294 ASPAAAVPTPEVAA-IPAASVPTPEVPAIPAAAVPPMEEV 1332 Score = 31.2 bits (69), Expect = 5.5 Identities = 56/274 (20%), Positives = 85/274 (31%), Gaps = 23/274 (8%) Query: 575 PEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQ 634 P + P KD L P PE S A G + + P P ++ L ++ ++ Sbjct: 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE 893 Query: 635 STQEPFTTKIP-RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV 693 P R T A T P T S P V A G +V Sbjct: 894 EDVTAAAVSAPERATVPAVTVSVPEG--TAAVAAVSSPEETAPAVAAAITQEGMS---AV 948 Query: 694 DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPT 753 P P+ P P+ P P P T STP Sbjct: 949 AGFSPEWAALAITVPITEEDGTP-EGPVTPATTVHAP-------EEPDTAAVRVSTPEEP 1000 Query: 754 GTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813 +P + T ++PT PA+ + +SP P +P V ++P + Sbjct: 1001 ASPAAAVPTP-EEPTSPAAAVP---TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056 Query: 814 CSITDSVKRFPKEEATEGNATSPPQNPPTNLTVV 847 ++ P+E + A P+ P + V Sbjct: 1057 AAVPT-----PEEPTSPAAAVPTPEEPTSPAAAV 1085 >gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 72.4 bits (176), Expect = 2e-12 Identities = 85/308 (27%), Positives = 122/308 (39%), Gaps = 36/308 (11%) Query: 322 SKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-TLASSEKPWIVP----TAKIS 376 S TP + S P T+TP + P T P++ L S T TL S P + P T S Sbjct: 5 SNTPTLTPSS--PPTLTPSSTPTLT-PSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61 Query: 377 EDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPS 436 + T T S+PT + +P ++ S T T + S PP TL PS Sbjct: 62 NTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPT---LTPSSPP-----------TLTPS 107 Query: 437 ETPFVPQKLEIFTSPEMQPT-TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK 495 TP + +P PT TP+ T + STP P +P T+ T + P Sbjct: 108 NTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPI 167 Query: 496 ISKSPEPTWT-------TPAPGKTQFISLKPKI-PLSPEVTHTKPAPKQTPRAPPKPKTS 547 +++S PT T TP+ T S P + P S + P TP + P S Sbjct: 168 LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPS 227 Query: 548 PRPRI-PQTQPVPKVPQRVTAKPKTSPSPEVSYT---TPAPKDVLLPHKPYPEVSQSEPA 603 P + P ++P+ T P ++P+ S T TP+ L P P ++ S Sbjct: 228 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNT-PTLTPSSTP 286 Query: 604 PLETRGIP 611 L P Sbjct: 287 TLTPSSTP 294 Score = 68.2 bits (165), Expect = 4e-11 Identities = 87/330 (26%), Positives = 128/330 (38%), Gaps = 37/330 (11%) Query: 432 TLAPSETPFVPQKLEIFTSPEMQPT-TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490 TL PS TP + +P PT TP+ Q + STP P P T T Sbjct: 1 TLTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60 Query: 491 TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP 550 + TP ++ S PT T P T ++ +P + S P TP +PP S P Sbjct: 61 SNTPTLTPSSTPTLT---PSSTPTLTPQPILTRS-------STPTLTPSSPPTLTPSNTP 110 Query: 551 RI-PQTQPVPKVPQRVTAKPKTSPSPEVSYT---TPAPKDVLLPHKPYPEVSQSEPAPLE 606 + P P T P ++P+ S T TP+ + + L P ++ S P+ Sbjct: 111 TLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPI-LTRSSTPTLTPSS-RPIL 168 Query: 607 TRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666 TR P ++PS + T T T T P + + + P T+ P Sbjct: 169 TRS--STPTLTPSSTP---TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP-----TLTP 218 Query: 667 RTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNV 726 S +P + P P + + R + S+ PT P + P L P T P N Sbjct: 219 --SSRPILTP--SSTPTLTPSSRPILTRSSTPTLTPSS-TPTLTPSNTPTL---TPSNTP 270 Query: 727 TGKPGSAGIISSGPITTPPLRSTPRPTGTP 756 T P + ++ P +TP L + PT TP Sbjct: 271 TLTPSNTPTLT--PSSTPTLTPSSTPTLTP 298 Score = 55.1 bits (131), Expect = 4e-07 Identities = 51/179 (28%), Positives = 69/179 (38%), Gaps = 9/179 (5%) Query: 336 TVTPETVPRSTKPTTSSALDVSETTLASSEKPWIV----PTAKISEDSKVLQPQTATYDV 391 T+TP P T +T + S TL S +P + PT S + + T T Sbjct: 119 TLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTP 178 Query: 392 FSSPTT--SDEPEISDSYTATSDRILDSIPPKTSRTLEQP--RATLAPSETP-FVPQKLE 446 S+PT S P ++ S T T I ++S P R L PS TP P Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238 Query: 447 IFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWT 505 I T TP+ T + +TP P P T T + TP ++ S PT T Sbjct: 239 ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLT 297 Score = 47.4 bits (111), Expect = 7e-05 Identities = 80/326 (24%), Positives = 108/326 (33%), Gaps = 51/326 (15%) Query: 534 PKQTPRAPPKPKTSPRPRI-PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHK 592 P TP +PP S P + P +QP+ T P + P+ TP+ L P Sbjct: 8 PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPT-----LTPSNTPTLTPSN 62 Query: 593 PYPEVSQSEPA--PLETRGIPFIPMISPSPSQEELQT-TLEETDQSTQEPFTTKIPRTTE 649 S P P T P ++P P T TL + T P T P T Sbjct: 63 TPTLTPSSTPTLTPSST------PTLTPQPILTRSSTPTLTPSSPPTLTPSNT--PTLTP 114 Query: 650 LAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPL 709 T P T S P + P PS R + S+ PT P +R P+ Sbjct: 115 SNTPTLTPSNTPTLT---PSSTPTLTPSSTPTLTPSS--RPILTRSSTPTLTPSSR--PI 167 Query: 710 PPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLER-IETDIKQPT 768 R + P P +T P +TP L + PT TP R I T PT Sbjct: 168 LTRSSTPTLTPSSTPTLT------------PSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215 Query: 769 VPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA 828 + S I SS+PT P R I ++P S Sbjct: 216 LTPSSRP---ILTPSSTPTLT-----------PSSRPILTRSSTPTLTPSSTPTLTPSNT 261 Query: 829 TEGNATSPPQNPPTNLTVVTVEGCPS 854 ++ P P+N +T P+ Sbjct: 262 PTLTPSNTPTLTPSNTPTLTPSSTPT 287 Score = 42.0 bits (97), Expect = 0.003 Identities = 44/162 (27%), Positives = 70/162 (43%), Gaps = 19/162 (11%) Query: 324 TPEVEKISARPTT--VTPETVPRSTKPTTSSALDVSETTLASSEKPWIVP--TAKISEDS 379 TP I R +T +TP + P T+ +T + S TL S P + P T ++ S Sbjct: 145 TPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 204 Query: 380 KVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILD-----SIPPKTSRTLEQPRA-TL 433 + + +++T + S P + + T +S IL ++ P ++ TL TL Sbjct: 205 RPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTL 264 Query: 434 APSETPFVPQKLEIFTSPEMQPT-TPAPQQTTSIPSTPKRRP 474 PS TP + +P PT TP+ T + STP P Sbjct: 265 TPSNTPTL--------TPSNTPTLTPSSTPTLTPSSTPTLTP 298 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.130 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,688,890 Number of Sequences: 37866 Number of extensions: 3237302 Number of successful extensions: 31694 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 316 Number of HSP's successfully gapped in prelim test: 1582 Number of HSP's that attempted gapping in prelim test: 13725 Number of HSP's gapped (non-prelim): 9461 length of query: 1075 length of database: 18,247,518 effective HSP length: 113 effective length of query: 962 effective length of database: 13,968,660 effective search space: 13437850920 effective search space used: 13437850920 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.