Guide to the Human Genome
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Search of human proteins with 33667044

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33667044 ABI gene family, member 3 (NESH) binding protein
[Homo sapiens]
         (1075 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho...  2201   0.0  
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...   316   7e-86
gi|116284392 mucin 2 precursor [Homo sapiens]                         120   7e-27
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  113   1e-24
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  113   1e-24
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  113   1e-24
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   113   1e-24
gi|163965366 nascent polypeptide-associated complex alpha subuni...   110   5e-24
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                       109   2e-23
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                       109   2e-23
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            102   2e-21
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              96   2e-19
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    93   1e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    87   6e-17
gi|91982772 mucin 17 [Homo sapiens]                                    87   1e-16
gi|110349719 titin isoform N2-A [Homo sapiens]                         84   7e-16
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                83   1e-15
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                83   1e-15
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                83   1e-15
gi|150170670 piccolo isoform 2 [Homo sapiens]                          82   3e-15
gi|150378539 piccolo isoform 1 [Homo sapiens]                          82   3e-15
gi|151301154 mucin 6, gastric [Homo sapiens]                           80   8e-15
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    80   1e-14
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        77   7e-14
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        77   1e-13
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        75   3e-13
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]       75   3e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    75   4e-13
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             72   2e-12
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    72   2e-12

>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
            sapiens]
          Length = 1075

 Score = 2201 bits (5702), Expect = 0.0
 Identities = 1075/1075 (100%), Positives = 1075/1075 (100%)

Query: 1    MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPN 60
            MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPN
Sbjct: 1    MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPN 60

Query: 61   VKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTR 120
            VKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTR
Sbjct: 61   VKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTR 120

Query: 121  SRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQI 180
            SRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQI
Sbjct: 121  SRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQI 180

Query: 181  CPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVP 240
            CPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVP
Sbjct: 181  CPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVP 240

Query: 241  AYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMF 300
            AYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMF
Sbjct: 241  AYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMF 300

Query: 301  EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETT 360
            EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETT
Sbjct: 301  EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETT 360

Query: 361  LASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPP 420
            LASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPP
Sbjct: 361  LASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPP 420

Query: 421  KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR 480
            KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR
Sbjct: 421  KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR 480

Query: 481  TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA 540
            TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA
Sbjct: 481  TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA 540

Query: 541  PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600
            PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS
Sbjct: 541  PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600

Query: 601  EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660
            EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF
Sbjct: 601  EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660

Query: 661  YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720
            YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP
Sbjct: 661  YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720

Query: 721  LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780
            LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT
Sbjct: 721  LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780

Query: 781  DFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840
            DFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP
Sbjct: 781  DFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840

Query: 841  PTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN 900
            PTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN
Sbjct: 841  PTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN 900

Query: 901  LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYS 960
            LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYS
Sbjct: 901  LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYS 960

Query: 961  ECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFL 1020
            ECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFL
Sbjct: 961  ECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFL 1020

Query: 1021 DGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW 1075
            DGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW
Sbjct: 1021 DGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW 1075


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score =  316 bits (810), Expect = 7e-86
 Identities = 236/674 (35%), Positives = 314/674 (46%), Gaps = 86/674 (12%)

Query: 470  PKRRPRPKPPRTKPERT--------TSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKI 521
            P +RP P PP + P  +         SA T++P     P P +TT AP      S  P +
Sbjct: 1239 PVKRPLPPPPGSSPRASHVPSRLPPRSAATVSPVAGTHPWPQYTTRAP--PGHFSTTPML 1296

Query: 522  PLSPEVTHTK---PAPKQTPRAPPKPKTSPRPRI-----PQTQPVPKVPQRVTAKPKTSP 573
             L   + H +   P  +Q  R   +   + RP +     P +   P   QR+   P+ + 
Sbjct: 1297 SLRQRMMHARFRNPLSRQPARPSYRQGYNGRPNVEGKVLPGSNGKPN-GQRIINGPQGT- 1354

Query: 574  SPEVSYTTPAPKDVLLPHKP-YPEVSQSEPAPLETRG-------IPFIPMISPSP----S 621
                 +     + ++L  +  Y + S   P  ++  G       +   P++SP       
Sbjct: 1355 ----KWVVDLDRGLVLNAEGRYLQDSHGNPLRIKLGGDGRTIVDLEGTPVVSPDGLPLFG 1410

Query: 622  QEELQTTLEETDQST-----QEPF--------TTKIPRTTELAKTTQAPHRFYTTVRPRT 668
            Q    T L             +P         TT  P TT    TT  P    TT RP T
Sbjct: 1411 QGRHGTPLANAQDKPILSLGGKPLVGLEVIKKTTHPPTTTMQPTTTTTPLPTTTTPRPTT 1470

Query: 669  SDKPHIRPGVKQAPR-PSGADRNVSVDSTHPTKKPGTRRPPLPP----RPTHPRRKPLPP 723
            +         +   R P+   R  +  +T  T  P T  P  PP    R        +  
Sbjct: 1471 ATTRRTTTTRRTTTRRPTTTVRTTTRTTTTTTPTPTTPIPTCPPGTLERHDDDGNLIMSS 1530

Query: 724  NNV----TGKPGSAGIISSGPITTPPLR---------STPRPTGTPLERIETDIKQPTVP 770
            N +      +   +G+ +   + T              T RP  T  E   T      +P
Sbjct: 1531 NGIPECYAEEDEFSGLETDTAVPTEEAYVIYDEDYEFETSRPP-TTTEPSTTATTPRVIP 1589

Query: 771  ASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATE 830
              G         SS P  E D  G+ RF  P+V Y+ K  ++PCS+TD++  F  +   E
Sbjct: 1590 EEGA-------ISSFPEEEFDLAGRKRFVAPYVTYLNKDPSAPCSLTDALDHFQVDSLDE 1642

Query: 831  ------GNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPL-NDTVTEYEVISRENGSFSG 883
                    +  PPQ+ P N+TVV VEGC SFVI+DW+K    D VT Y V S     F  
Sbjct: 1643 IIPNDLKKSDLPPQHAPRNITVVAVEGCHSFVIVDWDKATPGDVVTGYLVYSASYEDFIR 1702

Query: 884  KNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPR-VSEPVS 942
               S Q ++ T   +ENLKPNT Y F+V+ +NP G GP+S +V+F TES +P  V  P  
Sbjct: 1703 NKWSTQASSVTHLPIENLKPNTRYYFKVQAQNPHGYGPISPSVSFVTESDNPLLVVRP-- 1760

Query: 943  AGRDAIWTERPFNSD-SYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYN 1001
             G + IW    F  D SY++C G+QYVKRTWY+KFVGV LCNSLRYKIYLSD+L   FY+
Sbjct: 1761 PGGEPIWIPFAFKHDPSYTDCHGRQYVKRTWYRKFVGVVLCNSLRYKIYLSDNLKDTFYS 1820

Query: 1002 IGDQRGHGEDHCQFVDSFLDGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINY 1061
            IGD  G GEDHCQFVDS LDGRTG Q   + LP  +GY+R  RQEPV+FG IG  T   Y
Sbjct: 1821 IGDSWGRGEDHCQFVDSHLDGRTGPQSYVEALPTIQGYYRQYRQEPVRFGNIGFGTPYYY 1880

Query: 1062 VQWYECGTTIPGKW 1075
            V WYECG +IPGKW
Sbjct: 1881 VGWYECGVSIPGKW 1894



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 184/886 (20%), Positives = 312/886 (35%), Gaps = 148/886 (16%)

Query: 39  LKVHINTTSDSILLKFLRP------SPNVKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAI 92
           L+V + ++ D + + +  P      SP  +  G LLGYG +     Y PL  + + T  I
Sbjct: 162 LRVRVRSSDDRLSVAWKAPRLSGAKSPR-RSRGFLLGYGESGRKMNYVPLTRDER-THEI 219

Query: 93  VDAEPKYLIVVRPAPPPSQ------------KKSCSGKTRSRKPLQLVVGTLTPSSVFLS 140
                + + VV      SQ            K+  S +     P  + V  ++  SV +S
Sbjct: 220 KKLASESVYVVSLQSMNSQGRSQPVYRAALTKRKISEEDELDVPDDISVRVMSSQSVLVS 279

Query: 141 WGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQICPATETIVENLKPNTVYEFG 200
           W   +       + S     R YT+RYREK +  +W ++       ++ENL P+TVYEF 
Sbjct: 280 WVDPVLEKQKKVVAS-----RQYTVRYREKGELARWDYKQIANRRVLIENLIPDTVYEFA 334

Query: 201 VK--DNVEGGIWSKIFNHKTVVGSK----------KVNGK---IQSTYDQDHTVPAYVPR 245
           V+       G WS     +T   +            VNGK   + +++D        V  
Sbjct: 335 VRISQGERDGKWSTSVFQRTPESAPTTAPENLNVWPVNGKPTVVAASWDALPETEGKVKE 394

Query: 246 KLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASL------M 299
            ++                 + +P   P G   L +   PG  +TT  L   L      +
Sbjct: 395 YIL-----------------SYAPALKPFGAKSLTY---PG--DTTSALVDGLQPGERYL 432

Query: 300 FEISDALKTQL---AKNETLALPAESKT--------------PEVEKISAR-PTTVTPET 341
           F+I    +  L   +K   +A+P  SK               PE    S R P +    +
Sbjct: 433 FKIRATNRRGLGPHSKAFIVAMPTTSKADVEQNTEDNGKPEKPEPSSPSPRAPASSQHPS 492

Query: 342 VPRSTKPTTSS--ALDVSETTLASS---EKPWIVPTAKISEDSKVLQPQTATYDVFSSPT 396
           VP S +   +    LD+    LA+     KP +   AK +E+  +   +    +   S  
Sbjct: 493 VPASPQGRNAKDLLLDLKNKILANGGAPRKPQL--RAKKAEELDLQSTEITGEEELGS-- 548

Query: 397 TSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPT 456
             ++  +S S T    R L   P +   ++  P  T   +  P +P++  +        T
Sbjct: 549 -REDSPMSPSDTQDQKRTLRP-PSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLAT 606

Query: 457 TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFIS 516
            P P    S  ++P      +    +P    S        S   E    +  P K  F  
Sbjct: 607 QPRPGAPPSASASPAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVGSLHP-KGAF-- 663

Query: 517 LKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPE 576
            +P+  LSP         +Q+P +  + ++S  P      P  + P    A+  +S S  
Sbjct: 664 AQPRPALSPS--------RQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAP 715

Query: 577 VSYTTP--APKDVLLPHKPYPEVSQS------EPAPLETRGIPFIPMISPS-----PSQE 623
            S  +P       LLP +P+     S      E AP      P    +S S      S+ 
Sbjct: 716 PSRLSPPHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAPSRSTMSSSVSSHLSSRT 775

Query: 624 ELQTTLEETD-----QSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGV 678
           ++    E +D        +E    +   T +  +   A   F+         KP    G 
Sbjct: 776 QVSEGAEASDGESHGDGDREDGGRQAEATAQTLRARPASGHFHL-----LRHKPFAANGR 830

Query: 679 KQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPR-PTHPR-RKPLPPNNVTGKPGSAGII 736
             +    G    +   S+  +  P    P +P    +HP+    +  +    KP  A ++
Sbjct: 831 SPSRFSIGRGPRLQPSSSPQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVV 890

Query: 737 SSGPITTPPLRSTPRPTGTPLERIETDIKQ-PTVPASGEELENITDFSSSPTRETDPLGK 795
           +            P  +  P+ R   D+++ P   AS    E I +   S   +T P GK
Sbjct: 891 ND---------HVPSSSRQPISRGWEDLRRSPQRGASLHRKEPIPENPKSTGADTHPQGK 941

Query: 796 PRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPP 841
                   + +Q+  ++     D+    PK +    +  + P  PP
Sbjct: 942 YSSLASKAQDVQQSTDA-----DTEGHSPKAQPGSTDRHASPARPP 982



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 77/342 (22%), Positives = 134/342 (39%), Gaps = 38/342 (11%)

Query: 429  PRATLAPSETPFVPQKLE--------IFTSPEMQPTTPAPQQTTSIPSTPKRRPRPK--- 477
            P++T+     P VP   +        I    E +   PA      +PS+  R+P  +   
Sbjct: 849  PQSTVPSRAHPRVPSHSDSHPKLSSGIHGDEEDEKPLPATVVNDHVPSS-SRQPISRGWE 907

Query: 478  PPRTKPERTTSAGTITPKISKSPEPTWTTPAP-GKTQFISLKPK-IPLSPEVTHTKPAPK 535
              R  P+R  S     P I ++P+ T     P GK   ++ K + +  S +      +PK
Sbjct: 908  DLRRSPQRGASLHRKEP-IPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPK 966

Query: 536  QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVT--AKPKTSPSPEVS----YTTPAPKDV-L 588
              P +  +  +  RP   ++Q  P VP+R+T    P+  P P V+    +  P  +D   
Sbjct: 967  AQPGSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGR 1026

Query: 589  LPHKPYPEVSQS-EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT 647
             P +P   ++Q+  P P              + S+  L T L+  D+  Q  +      +
Sbjct: 1027 SPSQPRLSLTQAGRPRPTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDD---S 1083

Query: 648  TEL-AKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706
            TE+ A+  +AP         R  +     P  +Q   P+GA         H +++     
Sbjct: 1084 TEVEAQDVRAPAH-----AARAKEAAASLPKHQQVESPTGA----GAGGDHRSQRGHAAS 1134

Query: 707  PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRS 748
            P  P RP  P+ +   P+     PG +   S  P+++   +S
Sbjct: 1135 PARPSRPGGPQSRARVPSRAA--PGKSEPPSKRPLSSKSQQS 1174



 Score = 37.4 bits (85), Expect = 0.077
 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 453  MQPTT---PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509
            MQPTT   P P  TT  P+T   R      RT   R T+    T + + +  PT TTP P
Sbjct: 1451 MQPTTTTTPLPTTTTPRPTTATTRRTTTTRRTTTRRPTTTVRTTTRTTTTTTPTPTTPIP 1510



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 4/102 (3%)

Query: 835 SPPQNPPTNLTVVTVEGCPSFVILDWEK-PLNDTVTEYEVISRENGSFSGKNKSIQMTNQ 893
           S P   P NL V  V G P+ V   W+  P  +   +  ++S          KS+     
Sbjct: 357 SAPTTAPENLNVWPVNGKPTVVAASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGD 416

Query: 894 TFST-VENLKPNTSYEFQVKPKNPLGEGPVSNT--VAFSTES 932
           T S  V+ L+P   Y F+++  N  G GP S    VA  T S
Sbjct: 417 TTSALVDGLQPGERYLFKIRATNRRGLGPHSKAFIVAMPTTS 458



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 10/80 (12%)

Query: 424  RTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP 483
            +T   P  T+ P+ T          T+P    TTP P   T+  +T  RR   + P T  
Sbjct: 1442 KTTHPPTTTMQPTTT----------TTPLPTTTTPRPTTATTRRTTTTRRTTTRRPTTTV 1491

Query: 484  ERTTSAGTITPKISKSPEPT 503
              TT   T T     +P PT
Sbjct: 1492 RTTTRTTTTTTPTPTTPIPT 1511



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 33/157 (21%)

Query: 454  QPTTPA-PQQTTSIPSTPKRRP-RPKPPRTKPERTTSAGTITPK---------------- 495
            +P+ P  PQ    +PS  +  P + +PP  +P  + S  +++ +                
Sbjct: 1137 RPSRPGGPQSRARVPS--RAAPGKSEPPSKRPLSSKSQQSVSAEDDEEEDAGFFKGGKED 1194

Query: 496  ISKSPEPTW---TTPAPGKTQFISL-----KPKIPLSPEVTHTKPAPKQTPRAPPKPKTS 547
            +  S  P W   +TP  GK    SL     +P I L+P      P  +  P   P P +S
Sbjct: 1195 LLSSSVPKWPSSSTPRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLP---PPPGSS 1251

Query: 548  PRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 584
            PR     ++  P+    V+    T P P+  YTT AP
Sbjct: 1252 PRASHVPSRLPPRSAATVSPVAGTHPWPQ--YTTRAP 1286



 Score = 30.4 bits (67), Expect = 9.4
 Identities = 14/28 (50%), Positives = 16/28 (57%)

Query: 175  KWIFQICPATETIVENLKPNTVYEFGVK 202
            KW  Q    T   +ENLKPNT Y F V+
Sbjct: 1704 KWSTQASSVTHLPIENLKPNTRYYFKVQ 1731


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  120 bits (301), Expect = 7e-27
 Identities = 114/396 (28%), Positives = 147/396 (37%), Gaps = 38/396 (9%)

Query: 334  PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFS 393
            P T TP   P ST     +      TT  ++  P   P+  I+  +    P T T     
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT--TTTTPPPTTTPSPPI 1458

Query: 394  SPTTSDEPEISDS--YTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSP 451
            S TT+  P  + S   T  S       PP T+ T   P  T +P  T  +       T P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518

Query: 452  EMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP-ERTTSAGTITPKISKSPEPTWTTPAPG 510
                TTP+P  TT+  +TP     P PP T P    TS  T+ P  + SP PT TT  P 
Sbjct: 1519 --PTTTPSPPTTTT--TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574

Query: 511  KTQFISLKPKIPLSPEVTHTKPAPKQTPRAP------PKPKTSPRPRIPQTQPVPKVPQR 564
             T         P  P +T T P P  TP  P      P P T+P P  P T P+      
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP--PTTTPITPPTST 1632

Query: 565  VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624
             T  P T+PSP  + TT  P        P P  + +   P+ T   P  P  +PS     
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTT----TPSPPTTTTPSPPITTTTTP-PPTTTPS----- 1682

Query: 625  LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRP 684
              + +  T        TT  P TT  +  T       TT  P ++  P   P     P P
Sbjct: 1683 --SPITTTPSPPTTTMTTPSPTTTPSSPIT-------TTTTPSSTTTPSPPPTTMTTPSP 1733

Query: 685  SGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720
            +      +  +T  T  P T   PL   P  P   P
Sbjct: 1734 TTTPSPPT--TTMTTLPPTTTSSPLTTTPLPPSITP 1767



 Score =  117 bits (294), Expect = 4e-26
 Identities = 155/649 (23%), Positives = 213/649 (32%), Gaps = 120/649 (18%)

Query: 319  PAESKTPEVEKISARPTTVTPE---TVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375
            P  + +P     +  P T TP    T   +  PTT+ +  +S TT          PT   
Sbjct: 1418 PTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTP 1477

Query: 376  SEDSKVLQPQTATYDVFSSPTTSDEPEISD-----SYTATSDRILDSIPPKTSRTLEQPR 430
            S  +    P T T      PTT+  P  +      + T T        PP T+ T   P 
Sbjct: 1478 SPPTTTPSPPTTTTTT-PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 431  ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490
             T +P  T  +       T P    TTP+P  TT+    P   P P P  T P   T   
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITT 1593

Query: 491  TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP 550
            T  P  +    PT TT  P  T   S     P++P  + T   P  TP  PP   T+P P
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653

Query: 551  RI-----PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP-----YPEVSQS 600
                     T P P +    T  P T+PS  ++ T   P   +    P      P  + +
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT 1713

Query: 601  EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660
             P+   T   P   M +PSP+      T   T  +T  P TT  P TT     +  P  F
Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPT---TTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770

Query: 661  --YTTVRPRT-------------SDKPHI-RPG--------------------------- 677
              ++T  P T             S KP+  +PG                           
Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPD 1830

Query: 678  --VKQAPRPSGADRNVSVDSTHPTKKPG-------------------------TRRPPLP 710
              + Q  +    D +V +   +  +KPG                         T      
Sbjct: 1831 VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTT 1890

Query: 711  PRPTHPRRKPL-PPNNVTGKPGSAGIISSGPITTP-----PLRSTPRPTGTPLER----I 760
              PT P   P+     VT  P   G  +  P TTP      +  TP PTGT         
Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1948

Query: 761  ETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSV 820
             T    PT   +G +    T  +++ T    P              Q P  +P + T +V
Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPITTTTTV 1999

Query: 821  KRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
               P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 2000 TPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2044



 Score =  114 bits (285), Expect = 5e-25
 Identities = 151/594 (25%), Positives = 213/594 (35%), Gaps = 71/594 (11%)

Query: 321  ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-----TLASSEKPWIVPTAKI 375
            E+ TP         TTVTP   P  T+  T++ +  + T     T   ++ P   P    
Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1950

Query: 376  SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTL---EQPRAT 432
            +  +    P T T    ++P T+    ++ + T T  +   + P  T+ T+     P  T
Sbjct: 1951 TTVTPTPTP-TGTQTPTTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008

Query: 433  LAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPERTT 487
              P+ TP          +P   PT      TT I +T    P P P     P T P  TT
Sbjct: 2009 QTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2065

Query: 488  SAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQ 536
            +  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T  P   Q
Sbjct: 2066 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQ 2124

Query: 537  TPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLP 590
            TP   P   T     +P P   QT     +    T  P  +P+  +   TTP      + 
Sbjct: 2125 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2184

Query: 591  HKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPFTT 642
              P P  +Q+      T      P  +P+ +Q    T        T   T   TQ P TT
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244

Query: 643  KIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTH 697
             I  TT +  T     TQ P    T +   T+  P   P   Q P  +      +V    
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--- 2299

Query: 698  PTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGT 755
            PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T  PT T
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359

Query: 756  PLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCS 815
            P+    T    PT   +G +    T  +++ T    P              Q P  +P +
Sbjct: 2360 PI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPIT 2408

Query: 816  ITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
             T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 2409 TTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458



 Score =  112 bits (281), Expect = 1e-24
 Identities = 149/580 (25%), Positives = 207/580 (35%), Gaps = 68/580 (11%)

Query: 333  RPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVF 392
            +PTT+T  T    T PTT+     +  T   +      PT      +  + P T T    
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGT 1939

Query: 393  SSPTT---SDEPEISDSYTATSDRILDSIPPKTSRTL---EQPRATLAPSETPFVPQKLE 446
             +PTT   +    ++ + T T  +   + P  T+ T+     P  T  P+ TP       
Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT- 1998

Query: 447  IFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPERTTSAGTITPKISKSPE 501
               +P   PT      TT I +T    P P P     P T P  TT+  T TP  + +  
Sbjct: 1999 --VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2056

Query: 502  PTWT----------TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPRAPPKPKT---- 546
            PT T          TP P  TQ  +  P I  +  VT T  P   QTP   P   T    
Sbjct: 2057 PTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115

Query: 547  -SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLPHKPYPEVSQSEPAP 604
             +P P   QT     +    T  P  +P+  +   TTP      +   P P  +Q+    
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175

Query: 605  LETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPFTTKIPRTTELAKT--- 653
              T      P  +P+ +Q    T        T   T   TQ P TT I  TT +  T   
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2235

Query: 654  --TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKP-GTRRPPLP 710
              TQ P    T +   T+  P   P   Q P  +      +V    PT  P GT+ P   
Sbjct: 2236 TGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQTPTTT 2290

Query: 711  PRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPLERIETDIKQPTV 769
            P  T     P P    T  P +  I ++  +T TP    T  PT TP+    T    PT 
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPTP 2348

Query: 770  PASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEAT 829
              +G +    T  +++ T    P              Q P  +P + T +V   P    T
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPITTTTTVTPTPTPTGT 2399

Query: 830  EGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
            +    +P   P T  T VT    P+        P+  T T
Sbjct: 2400 Q----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2435



 Score =  112 bits (281), Expect = 1e-24
 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T       P   PT      
Sbjct: 2120 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 2170

Query: 379  SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434
            +    P T T  V  +PT T  +   +   T T+       P  T      P     T+ 
Sbjct: 2171 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2230

Query: 435  PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481
            P+ TP     P    I T+  + PT P P       TT I +T    P P P     P T
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 482  KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530
             P  TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T 
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 2348

Query: 531  KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584
             P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP  
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 585  KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636
                +   P P  +Q+      T      P  +P+ +Q    T        T   T   T
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468

Query: 637  QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691
            Q P TT I  TT +  T     TQ P    T +   T+  P   P   Q P  +      
Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526

Query: 692  SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749
            +V    PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T
Sbjct: 2527 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 750  PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809
              PT TP+    T    PT   +G +    T  +++ T    P              Q P
Sbjct: 2584 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 2632

Query: 810  DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
              +P + T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688



 Score =  112 bits (281), Expect = 1e-24
 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T       P   PT      
Sbjct: 2442 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 2492

Query: 379  SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434
            +    P T T  V  +PT T  +   +   T T+       P  T      P     T+ 
Sbjct: 2493 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552

Query: 435  PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481
            P+ TP     P    I T+  + PT P P       TT I +T    P P P     P T
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 482  KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530
             P  TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T 
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 2670

Query: 531  KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584
             P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP  
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 585  KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636
                +   P P  +Q+      T      P  +P+ +Q    T        T   T   T
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790

Query: 637  QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691
            Q P TT I  TT +  T     TQ P    T +   T+  P   P   Q P  +      
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 2848

Query: 692  SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749
            +V    PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T
Sbjct: 2849 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905

Query: 750  PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809
              PT TP+    T    PT   +G +    T  +++ T    P              Q P
Sbjct: 2906 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 2954

Query: 810  DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
              +P + T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010



 Score =  112 bits (281), Expect = 1e-24
 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T       P   PT      
Sbjct: 2764 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 2814

Query: 379  SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434
            +    P T T  V  +PT T  +   +   T T+       P  T      P     T+ 
Sbjct: 2815 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874

Query: 435  PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481
            P+ TP     P    I T+  + PT P P       TT I +T    P P P     P T
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 482  KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530
             P  TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T 
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 2992

Query: 531  KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584
             P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP  
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 585  KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636
                +   P P  +Q+      T      P  +P+ +Q    T        T   T   T
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112

Query: 637  QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691
            Q P TT I  TT +  T     TQ P    T +   T+  P   P   Q P  +      
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170

Query: 692  SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749
            +V    PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T
Sbjct: 3171 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227

Query: 750  PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809
              PT TP+    T    PT   +G +    T  +++ T    P              Q P
Sbjct: 3228 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 3276

Query: 810  DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
              +P + T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332



 Score =  112 bits (281), Expect = 1e-24
 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T       P   PT      
Sbjct: 3086 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 3136

Query: 379  SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434
            +    P T T  V  +PT T  +   +   T T+       P  T      P     T+ 
Sbjct: 3137 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3196

Query: 435  PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481
            P+ TP     P    I T+  + PT P P       TT I +T    P P P     P T
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 482  KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530
             P  TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T 
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 3314

Query: 531  KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584
             P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP  
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 585  KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636
                +   P P  +Q+      T      P  +P+ +Q    T        T   T   T
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434

Query: 637  QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691
            Q P TT I  TT +  T     TQ P    T +   T+  P   P   Q P  +      
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492

Query: 692  SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749
            +V    PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T
Sbjct: 3493 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549

Query: 750  PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809
              PT TP+    T    PT   +G +    T  +++ T    P              Q P
Sbjct: 3550 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 3598

Query: 810  DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
              +P + T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 3599 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654



 Score =  112 bits (281), Expect = 1e-24
 Identities = 157/600 (26%), Positives = 214/600 (35%), Gaps = 80/600 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T       P   PT      
Sbjct: 3408 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 3458

Query: 379  SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434
            +    P T T  V  +PT T  +   +   T T+       P  T      P     T+ 
Sbjct: 3459 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518

Query: 435  PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481
            P+ TP     P    I T+  + PT P P       TT I +T    P P P     P T
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577

Query: 482  KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530
             P  TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T 
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 3636

Query: 531  KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584
             P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP  
Sbjct: 3637 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696

Query: 585  KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQST 636
                +   P P  +Q+      T      P  +P+ +Q    T        T   T   T
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3756

Query: 637  QEPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691
            Q P TT I  TT +  T     TQ P    T +   T+  P   P   Q P  +      
Sbjct: 3757 QTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814

Query: 692  SVDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRST 749
            +V    PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T
Sbjct: 3815 TVT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3871

Query: 750  PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP 809
              PT TP+    T    PT   +G +    T  +++ T    P              Q P
Sbjct: 3872 QTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTP 3920

Query: 810  DNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
              +P + T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3976



 Score =  108 bits (270), Expect = 3e-23
 Identities = 151/577 (26%), Positives = 203/577 (35%), Gaps = 83/577 (14%)

Query: 335  TTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED---SKVLQPQTATYD- 390
            TT+T  T P +   TT++    S T L+++ K   + +  I+ED   S        T+D 
Sbjct: 1269 TTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG 1328

Query: 391  VFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPF--------VP 442
            V  +P   +   + D + +     L+ +  K    +      +  +E  F          
Sbjct: 1329 VCGAPEDIECRSVKDPHLS-----LEQLGQKVQCDVSV--GFICKNEDQFGNGPFGLCYD 1381

Query: 443  QKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE-RTTSAGTITPKISKSP- 500
             K+ +     M      P   T+ PS P       PP T P   TT+  T  P  + SP 
Sbjct: 1382 YKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1441

Query: 501  ------EPTWTTPAPGKTQFISLKPKIPLSPEVT-----HTKPAPKQTPRAPPKPKTSPR 549
                   P  TTP+P  +   +  P    SP  T      T P+P  T    P P T+P 
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501

Query: 550  PRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609
            P  P T P+       T  P T+PSP  + TT  P        P P  +     P  T  
Sbjct: 1502 P--PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTT----TPSPPTTTPITPPTSTTT 1555

Query: 610  IPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTV-RPRT 668
            +P  P  +PSP           T  +T  P TT  P TT    TT +P    TT   P T
Sbjct: 1556 LP--PTTTPSP---------PPTTTTTPPPTTTPSPPTT----TTPSPPTITTTTPPPTT 1600

Query: 669  SDKPHIRPGVKQAP--RPSGADRNVSVDSTHPTKKPGTRRPPLPPRPT---HPRRKPLPP 723
            +  P         P   PS          T  T  P T  P  PP  T    P   P PP
Sbjct: 1601 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660

Query: 724  NNVTGKPGSAGIISSGPITTP--PLRSTPRP------TGTPLERIETDIKQPTVPASGEE 775
               T  P      +  P TTP  P+ +TP P      T +P     + I   T P+S   
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS--- 1717

Query: 776  LENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---DNSPCSITDSVKRFPKEEATEGN 832
                T  S  PT  T P        P       P    +SP + T           +  +
Sbjct: 1718 ---TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774

Query: 833  ATSP--PQNPPTNLTVVTVEGCPSFVILDWEKPLNDT 867
             T+P  P  P  N T     G P+F      KP  DT
Sbjct: 1775 TTTPTTPCVPLCNWTGWLDSGKPNF-----HKPGGDT 1806



 Score =  105 bits (262), Expect = 2e-22
 Identities = 151/569 (26%), Positives = 206/569 (36%), Gaps = 79/569 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T       P   PT      
Sbjct: 3730 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGT---Q 3780

Query: 379  SKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQP---RATLA 434
            +    P T T  V  +PT T  +   +   T T+       P  T      P     T+ 
Sbjct: 3781 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840

Query: 435  PSETPF---VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRT 481
            P+ TP     P    I T+  + PT P P       TT I +T    P P P     P T
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3899

Query: 482  KPERTTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT- 530
             P  TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T 
Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP 3958

Query: 531  KPAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAP 584
             P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP  
Sbjct: 3959 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018

Query: 585  KDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKI 644
                +   P P  +Q+      T  I     ++P+P           T   TQ P TT I
Sbjct: 4019 TTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTP-----------TPTGTQTPTTTPI 4063

Query: 645  PRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPT 699
              TT +  T     TQ P    T +   T+  P   P   Q P  +      +V    PT
Sbjct: 4064 TTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PT 4118

Query: 700  KKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPL 757
              P GT+ P   P  T     P P    T  P +  I ++  +T TP    T  PT TP+
Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4178

Query: 758  ERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSIT 817
                T    PT   +G +    T  S++P  E      P    P     Q   ++   +T
Sbjct: 4179 --TTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP----PESSTPQTSRSTSSPLT 4232

Query: 818  DSVKRFPK-EEATEGNATSPPQNPPTNLT 845
            +S         A E  +T+PP  P    T
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTT 4261



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 141/531 (26%), Positives = 187/531 (35%), Gaps = 85/531 (16%)

Query: 381  VLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPF 440
            V QP T T     +PT      I+ + T T        P  T      P  T  P+ TP 
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVT--------PTPT------PTGTQTPTTTP- 1923

Query: 441  VPQKLEIFTSPEMQPTTPAP-----QQTTSIPSTPKRRPRPKP-----PRTKPERTTSAG 490
                  I T+  + PT P P       TT I +T    P P P     P T P  TT+  
Sbjct: 1924 ------ITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1976

Query: 491  TITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPR 539
            T TP  + +  PT T          TP P  TQ  +  P I  +  VT T  P   QTP 
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPT 2035

Query: 540  APPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLPHKP 593
              P   T     +P P   QT     +    T  P  +P+  +   TTP      +   P
Sbjct: 2036 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2095

Query: 594  YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPFTTKIP 645
             P  +Q+      T      P  +P+ +Q    T        T   T   TQ P TT I 
Sbjct: 2096 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 646  RTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700
             TT +  T     TQ P    T +   T+  P   P   Q P  +      +V    PT 
Sbjct: 2156 TTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTP 2210

Query: 701  KP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPLE 758
             P GT+ P   P  T     P P    T  P +  I ++  +T TP    T  PT TP+ 
Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2269

Query: 759  RIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITD 818
               T    PT   +G +    T  +++ T    P              Q P  +P + T 
Sbjct: 2270 -TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPTTTPITTTT 2319

Query: 819  SVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
            +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 2320 TVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2366



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 132/520 (25%), Positives = 186/520 (35%), Gaps = 66/520 (12%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-----TLASSEKPWIVPTA 373
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T     T   ++ P   P  
Sbjct: 3822 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880

Query: 374  KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ---PR 430
              +  +    P T T    ++P T+    ++ + T T  +   + P  T+ T+     P 
Sbjct: 3881 TTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3938

Query: 431  ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPER 485
             T  P+ TP          +P   PT      TT I +T    P P P     P T P  
Sbjct: 3939 GTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3995

Query: 486  TTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHTK-PAP 534
            TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T  P  
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTG 4054

Query: 535  KQTPRAPPKPKTS-----PRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVL 588
             QTP   P   T+     P P   QT     +    T  P  +P+  +   TTP      
Sbjct: 4055 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4114

Query: 589  LPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQEPF 640
            +   P P  +Q+      T      P  +P+ +Q    T        T   T   TQ P 
Sbjct: 4115 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174

Query: 641  TTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700
            TT I  TT +  T   P    T     TS  P I       P P  +    S  ++ P  
Sbjct: 4175 TTPITTTTTVTPTP-TPTGTQTGPPTHTSTAP-IAELTTSNPPPESSTPQTSRSTSSPLT 4232

Query: 701  KPGTRRPPLPPR----PTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTP 756
            +  T    LPP      T P   P  P   +G          G   +PP  +T  P GTP
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----------GHTLSPPPSTTTSPPGTP 4282

Query: 757  LERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKP 796
                 T       P++ +     T  +S+ T    PL  P
Sbjct: 4283 TRGTTTGSSSAPTPSTVQ-----TTTTSAWTPTPTPLSTP 4317



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 107/419 (25%), Positives = 147/419 (35%), Gaps = 54/419 (12%)

Query: 484  ERTTSAGTITPKISKSPEPTWT-----------TPAPGKTQFISLKPKIPLSPEVTHT-K 531
            E  T   T+T   +++P P  T           TP P  TQ  +  P I  +  VT T  
Sbjct: 1877 ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT 1935

Query: 532  PAPKQTPRAPPKPKT-----SPRPRIPQTQPVPKVPQRVTAKPKTSPS-PEVSYTTPAPK 585
            P   QTP   P   T     +P P   QT     +    T  P  +P+  +   TTP   
Sbjct: 1936 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1995

Query: 586  DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--------TLEETDQSTQ 637
               +   P P  +Q+      T      P  +P+ +Q    T        T   T   TQ
Sbjct: 1996 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2055

Query: 638  EPFTTKIPRTTELAKT-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692
             P TT I  TT +  T     TQ P    T +   T+  P   P   Q P  +      +
Sbjct: 2056 TPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2113

Query: 693  VDSTHPTKKP-GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTP 750
            V    PT  P GT+ P   P  T     P P    T  P +  I ++  +T TP    T 
Sbjct: 2114 VT---PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2170

Query: 751  RPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPD 810
             PT TP+    T    PT   +G +    T  +++ T    P              Q P 
Sbjct: 2171 TPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG---------TQTPT 2219

Query: 811  NSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVT 869
             +P + T +V   P    T+    +P   P T  T VT    P+        P+  T T
Sbjct: 2220 TTPITTTTTVTPTPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 124/482 (25%), Positives = 173/482 (35%), Gaps = 101/482 (20%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-----TLASSEKPWIVPTA 373
            P  ++TP    I+   TTVTP   P  T+  T++ +  + T     T   ++ P   P  
Sbjct: 3960 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018

Query: 374  KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ---PR 430
              +  +    P T T    ++P T+    ++ + T T  +   + P  T+ T+     P 
Sbjct: 4019 TTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076

Query: 431  ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP-----PRTKPER 485
             T  P+ TP          +P   PT      TT I +T    P P P     P T P  
Sbjct: 4077 GTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133

Query: 486  TTSAGTITPKISKSPEPTWT----------TPAPGKTQFISLKPKIPLSPEVTHTKPAPK 535
            TT+  T TP  + +  PT T          TP P  TQ  +  P I  +  VT T P P 
Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPT-PTPT 4191

Query: 536  QTPRAPPK-PKTSPRPRIPQTQPVPK--VPQ--RVTAKPKTS---------PSPEVSYTT 581
             T   PP    T+P   +  + P P+   PQ  R T+ P T          P+ E++ T 
Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA 4251

Query: 582  P-----APKDVLLPH--KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQ 634
            P     AP      H   P P  + S P    TRG       +P+PS   +QTT      
Sbjct: 4252 PPSTPTAPTTTSGGHTLSPPPSTTTSPPGT-PTRGTTTGSSSAPTPST--VQTTTTSAWT 4308

Query: 635  STQEPFTT-KIPRTTELAK-------------TTQAPHR--------------------- 659
             T  P +T  I RTT L               T  AP                       
Sbjct: 4309 PTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCT 4368

Query: 660  --FYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPR 717
              FY    P T             P PS +    S  S+ P+K     +PP  P    PR
Sbjct: 4369 LEFYNWSCPSTPSP---------TPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPR 4419

Query: 718  RK 719
            ++
Sbjct: 4420 QE 4421



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 58/259 (22%), Positives = 85/259 (32%), Gaps = 57/259 (22%)

Query: 310  LAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWI 369
            +A+  T   P ES TP+  + ++ P T                      TTL S+  P I
Sbjct: 4206 IAELTTSNPPPESSTPQTSRSTSSPLT--------------------ESTTLLSTLPPAI 4245

Query: 370  VPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQP 429
                   E +    P T T     +PTT+     S  +T +      + PP T       
Sbjct: 4246 -------EMTSTAPPSTPT-----APTTT-----SGGHTLSPPPSTTTSPPGT-----PT 4283

Query: 430  RATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSA 489
            R T   S +   P  ++  T+    P TP P  T SI  T   RP        P      
Sbjct: 4284 RGTTTGSSSAPTPSTVQTTTTSAWTP-TPTPLSTPSIIRTTGLRP-------YPSSVLIC 4335

Query: 490  GTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLS------PEVTHTKPAPKQTPRAPPK 543
              +        E  +         F++      L       P      P P ++   P K
Sbjct: 4336 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK 4395

Query: 544  PKTSPRPRIPQTQPVPKVP 562
            P ++P    P T+P P+ P
Sbjct: 4396 PSSTPSKPTPGTKP-PECP 4413


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  113 bits (282), Expect = 1e-24
 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%)

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374
           P  S  P  +       TV  ET   + + TT++   + D  E T ++ E   I  T+  
Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185

Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420
            ++  SKVL   T   +  +           +PTT  EP  +     T T+ +   + P 
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245

Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472
           + + T  +   T      P   ++    T  E  PTT   PAP  T S P+TPK      
Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305

Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518
             +P P   K    T+    TP   K P PT   PA              P  T      
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568
           P  P  P  T TK         PAP  T  AP   K  P P   ++ P  PK P   T K
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 424

Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625
                +P E + TTP       P +P P  +  EPAP  T +  P  P   +P+  +E  
Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483

Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679
            TT ++   +T E   P T + P  T   ELA TT       T   P  +      P   
Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 543

Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739
           + P P+            P         P  P+ T P     P      KP    +    
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 600

Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792
           P TT    ST    P PT TP     T  K+P  P + +E    T   ++PT   +P   
Sbjct: 601 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 658

Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839
                    L     KGP      KP  +P +  ++    PKE A     +   T+P   
Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 716

Query: 840 PPTNLTVVT 848
           PPT   V T
Sbjct: 717 PPTTSEVST 725



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%)

Query: 290 TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345
           TT K PA    + +     + A   T + P   K P     +  P   TP+    T P+ 
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 441

Query: 346 TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400
             PTT    +     E    +++KP   PT    E +     +TA T     +PTT ++ 
Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 498

Query: 401 -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
            P   +    T+   L    P+  T  T E+P  T   +  P  P++    T  E  PTT
Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558

Query: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508
           P        P+TPK      P  T P         TPK         + + EPT TT   
Sbjct: 559 PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614

Query: 509 PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567
           P  T      P  P  P  T  K PAP       P     P P  P+ +P PK     T 
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 673

Query: 568 KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611
           K  TS     P+P    E + TTP       P KP P   ++ P        P  T+  P
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 732

Query: 612 FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663
                SP  S  EL  + T +  + S +EP   TTK P  T+   TT A      R   T
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792

Query: 664 VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723
               T+  P +    K+    +       + +T       T +   P + T  +   L P
Sbjct: 793 TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 849

Query: 724 NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783
              T K           ITT  + + P  T  P +R           A+  + +  T   
Sbjct: 850 KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 894

Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843
             PT    P   PR + P      +   S     +   R    EA     T P Q P + 
Sbjct: 895 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 952

Query: 844 LTVV 847
           L  V
Sbjct: 953 LVEV 956



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 291  TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347
            T K PA+   E++   K +  + +    P   +  P++ K +A  T  T E+     +T+
Sbjct: 766  TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 825

Query: 348  PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407
             T+++  D +   + + +   + P  K++   K +     T ++ + P  + +P+     
Sbjct: 826  VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 876

Query: 408  TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459
             AT+ +     P K ++  ++P +T  P   P V        P+K+   T PE+ PT+  
Sbjct: 877  -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 934

Query: 460  PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519
             +      + P + P  K     P+   + G                 A G+T  + L+P
Sbjct: 935  AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 977

Query: 520  KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558
             +   PEVT   P     PR P +     P  S    I   +PV
Sbjct: 978  HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1017



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 88/394 (22%), Positives = 132/394 (33%), Gaps = 50/394 (12%)

Query: 568 KPKTSPSPEVSYTTPAPKD-----VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQ 622
           K K +P P V     +  D     V  P     + ++   +P  T   P    I+P PS 
Sbjct: 75  KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSL 130

Query: 623 EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPG 677
                T +ET  +  +  T +   TT   K T    +  TT    T     +    + P 
Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 190

Query: 678 VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIIS 737
            K   +P+             T K      P  P PT P+     P + T K  +   I 
Sbjct: 191 SKVLAKPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 238

Query: 738 SGPITTP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPL 793
           S P TTP    P  +   PT TP E   T  K+P  P + +E    T    +PT      
Sbjct: 239 SAP-TTPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAP 295

Query: 794 GKPRFKGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVV 847
             P+   P       P    + +P +  +     PKE A  T+  A + P+ P       
Sbjct: 296 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355

Query: 848 TVEGCPSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTS 906
                P       ++P   T  E     ++E    + K  +   T    +T +   P T+
Sbjct: 356 PAPTTP-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 907 YEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP 940
                 PK P    P +      T   +P  + P
Sbjct: 409 KSAPTTPKEP---SPTTTKEPAPTTPKEPAPTTP 439


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  113 bits (282), Expect = 1e-24
 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%)

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374
           P  S  P  +       TV  ET   + + TT++   + D  E T ++ E   I  T+  
Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226

Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420
            ++  SKVL   T   +  +           +PTT  EP  +     T T+ +   + P 
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286

Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472
           + + T  +   T      P   ++    T  E  PTT   PAP  T S P+TPK      
Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346

Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518
             +P P   K    T+    TP   K P PT   PA              P  T      
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568
           P  P  P  T TK         PAP  T  AP   K  P P   ++ P  PK P   T K
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 465

Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625
                +P E + TTP       P +P P  +  EPAP  T +  P  P   +P+  +E  
Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524

Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679
            TT ++   +T E   P T + P  T   ELA TT       T   P  +      P   
Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 584

Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739
           + P P+            P         P  P+ T P     P      KP    +    
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 641

Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792
           P TT    ST    P PT TP     T  K+P  P + +E    T   ++PT   +P   
Sbjct: 642 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 699

Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839
                    L     KGP      KP  +P +  ++    PKE A     +   T+P   
Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 757

Query: 840 PPTNLTVVT 848
           PPT   V T
Sbjct: 758 PPTTSEVST 766



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%)

Query: 290 TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345
           TT K PA    + +     + A   T + P   K P     +  P   TP+    T P+ 
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 482

Query: 346 TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400
             PTT    +     E    +++KP   PT    E +     +TA T     +PTT ++ 
Sbjct: 483 PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 539

Query: 401 -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
            P   +    T+   L    P+  T  T E+P  T   +  P  P++    T  E  PTT
Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599

Query: 458 PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508
           P        P+TPK      P  T P         TPK         + + EPT TT   
Sbjct: 600 PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655

Query: 509 PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567
           P  T      P  P  P  T  K PAP       P     P P  P+ +P PK     T 
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 714

Query: 568 KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611
           K  TS     P+P    E + TTP       P KP P   ++ P        P  T+  P
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 773

Query: 612 FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663
                SP  S  EL  + T +  + S +EP   TTK P  T+   TT A      R   T
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833

Query: 664 VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723
               T+  P +    K+    +       + +T       T +   P + T  +   L P
Sbjct: 834 TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 890

Query: 724 NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783
              T K           ITT  + + P  T  P +R           A+  + +  T   
Sbjct: 891 KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 935

Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843
             PT    P   PR + P      +   S     +   R    EA     T P Q P + 
Sbjct: 936 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 993

Query: 844 LTVV 847
           L  V
Sbjct: 994 LVEV 997



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 291  TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347
            T K PA+   E++   K +  + +    P   +  P++ K +A  T  T E+     +T+
Sbjct: 807  TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 866

Query: 348  PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407
             T+++  D +   + + +   + P  K++   K +     T ++ + P  + +P+     
Sbjct: 867  VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 917

Query: 408  TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459
             AT+ +     P K ++  ++P +T  P   P V        P+K+   T PE+ PT+  
Sbjct: 918  -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 975

Query: 460  PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519
             +      + P + P  K     P+   + G                 A G+T  + L+P
Sbjct: 976  AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 1018

Query: 520  KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558
             +   PEVT   P     PR P +     P  S    I   +PV
Sbjct: 1019 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1058



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 88/394 (22%), Positives = 132/394 (33%), Gaps = 50/394 (12%)

Query: 568 KPKTSPSPEVSYTTPAPKD-----VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQ 622
           K K +P P V     +  D     V  P     + ++   +P  T   P    I+P PS 
Sbjct: 116 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSL 171

Query: 623 EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPG 677
                T +ET  +  +  T +   TT   K T    +  TT    T     +    + P 
Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 231

Query: 678 VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIIS 737
            K   +P+             T K      P  P PT P+     P + T K  +   I 
Sbjct: 232 SKVLAKPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 279

Query: 738 SGPITTP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPL 793
           S P TTP    P  +   PT TP E   T  K+P  P + +E    T    +PT      
Sbjct: 280 SAP-TTPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAP 336

Query: 794 GKPRFKGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVV 847
             P+   P       P    + +P +  +     PKE A  T+  A + P+ P       
Sbjct: 337 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396

Query: 848 TVEGCPSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTS 906
                P       ++P   T  E     ++E    + K  +   T    +T +   P T+
Sbjct: 397 PAPTTP-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 907 YEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP 940
                 PK P    P +      T   +P  + P
Sbjct: 450 KSAPTTPKEP---SPTTTKEPAPTTPKEPAPTTP 480


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  113 bits (282), Expect = 1e-24
 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%)

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374
           P  S  P  +       TV  ET   + + TT++   + D  E T ++ E   I  T+  
Sbjct: 219 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278

Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420
            ++  SKVL   T   +  +           +PTT  EP  +     T T+ +   + P 
Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338

Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472
           + + T  +   T      P   ++    T  E  PTT   PAP  T S P+TPK      
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 398

Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518
             +P P   K    T+    TP   K P PT   PA              P  T      
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458

Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568
           P  P  P  T TK         PAP  T  AP   K  P P   ++ P  PK P   T K
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 517

Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625
                +P E + TTP       P +P P  +  EPAP  T +  P  P   +P+  +E  
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576

Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679
            TT ++   +T E   P T + P  T   ELA TT       T   P  +      P   
Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636

Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739
           + P P+            P         P  P+ T P     P      KP    +    
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 693

Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792
           P TT    ST    P PT TP     T  K+P  P + +E    T   ++PT   +P   
Sbjct: 694 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 751

Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839
                    L     KGP      KP  +P +  ++    PKE A     +   T+P   
Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809

Query: 840 PPTNLTVVT 848
           PPT   V T
Sbjct: 810 PPTTSEVST 818



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%)

Query: 290  TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345
            TT K PA    + +     + A   T + P   K P     +  P   TP+    T P+ 
Sbjct: 476  TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 534

Query: 346  TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400
              PTT    +     E    +++KP   PT    E +     +TA T     +PTT ++ 
Sbjct: 535  PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 591

Query: 401  -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
             P   +    T+   L    P+  T  T E+P  T   +  P  P++    T  E  PTT
Sbjct: 592  APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 651

Query: 458  PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508
            P        P+TPK      P  T P         TPK         + + EPT TT   
Sbjct: 652  PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707

Query: 509  PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567
            P  T      P  P  P  T  K PAP       P     P P  P+ +P PK     T 
Sbjct: 708  PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 766

Query: 568  KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611
            K  TS     P+P    E + TTP       P KP P   ++ P        P  T+  P
Sbjct: 767  KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 825

Query: 612  FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663
                 SP  S  EL  + T +  + S +EP   TTK P  T+   TT A      R   T
Sbjct: 826  TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885

Query: 664  VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723
                T+  P +    K+    +       + +T       T +   P + T  +   L P
Sbjct: 886  TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 942

Query: 724  NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783
               T K           ITT  + + P  T  P +R           A+  + +  T   
Sbjct: 943  KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 987

Query: 784  SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843
              PT    P   PR + P      +   S     +   R    EA     T P Q P + 
Sbjct: 988  KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 1045

Query: 844  LTVV 847
            L  V
Sbjct: 1046 LVEV 1049



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 116/509 (22%), Positives = 179/509 (35%), Gaps = 63/509 (12%)

Query: 449 TSPEMQPTTPAPQQTT-SIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTP 507
           TSP      P P   + +I ST KR P+P P + K ++   +  IT + S S     ++ 
Sbjct: 70  TSPPSSKKAPPPSGASQTIKSTTKRSPKP-PNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 508 APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567
           +   +   +++ KI  S      +   K+      K K + + R  + +P PK P  V  
Sbjct: 129 SSSSSSSSTIR-KIKSSKNSAANRELQKKL-----KVKDNKKNRTKK-KPTPKPPV-VDE 180

Query: 568 KPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT 627
                 + +   TTP           + +VS S   P  T   P    I+P PS      
Sbjct: 181 AGSGLDNGDFKVTTPDTSTT-----QHNKVSTS---PKITTAKP----INPRPSLPPNSD 228

Query: 628 TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPGVKQAP 682
           T +ET  +  +  T +   TT   K T    +  TT    T     +    + P  K   
Sbjct: 229 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 288

Query: 683 RPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT 742
           +P+             T K      P  P PT P+     P + T K  +   I S P T
Sbjct: 289 KPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAP-T 335

Query: 743 TP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRF 798
           TP    P  +   PT TP E   T  K+P  P + +E    T    +PT        P+ 
Sbjct: 336 TPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393

Query: 799 KGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVVTVEGC 852
             P       P    + +P +  +     PKE A  T+  A + P+ P            
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 453

Query: 853 PSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQV 911
           P       ++P   T  E     ++E    + K  +   T    +T +   P T+     
Sbjct: 454 P-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506

Query: 912 KPKNPLGEGPVSNTVAFSTESADPRVSEP 940
            PK P    P +      T   +P  + P
Sbjct: 507 TPKEP---SPTTTKEPAPTTPKEPAPTTP 532



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 291  TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347
            T K PA+   E++   K +  + +    P   +  P++ K +A  T  T E+     +T+
Sbjct: 859  TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 918

Query: 348  PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407
             T+++  D +   + + +   + P  K++   K +     T ++ + P  + +P+     
Sbjct: 919  VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 969

Query: 408  TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459
             AT+ +     P K ++  ++P +T  P   P V        P+K+   T PE+ PT+  
Sbjct: 970  -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 1027

Query: 460  PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519
             +      + P + P  K     P+   + G                 A G+T  + L+P
Sbjct: 1028 AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 1070

Query: 520  KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558
             +   PEVT   P     PR P +     P  S    I   +PV
Sbjct: 1071 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1110


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  113 bits (282), Expect = 1e-24
 Identities = 160/609 (26%), Positives = 217/609 (35%), Gaps = 88/609 (14%)

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSS---ALDVSETTLASSEKPWIVPTAK- 374
           P  S  P  +       TV  ET   + + TT++   + D  E T ++ E   I  T+  
Sbjct: 260 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319

Query: 375 -ISEDSKVLQPQTATYDVFS-----------SPTTSDEPEISDSY--TATSDRILDSIPP 420
            ++  SKVL   T   +  +           +PTT  EP  +     T T+ +   + P 
Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379

Query: 421 KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT---PAPQQTTSIPSTPKR----- 472
           + + T  +   T      P   ++    T  E  PTT   PAP  T S P+TPK      
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 439

Query: 473 RPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPA--------------PGKTQFISLK 518
             +P P   K    T+    TP   K P PT   PA              P  T      
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499

Query: 519 PKIPLSPEVTHTK---------PAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAK 568
           P  P  P  T TK         PAP  T  AP   K  P P   ++ P  PK P   T K
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK-EPAPTTTKSAPTTPKEPSPTTTK 558

Query: 569 PKTSPSP-EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFIPM-ISPSPSQEEL 625
                +P E + TTP       P +P P  +  EPAP  T +  P  P   +P+  +E  
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617

Query: 626 QTTLEETDQSTQE---PFTTKIPRTT---ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679
            TT ++   +T E   P T + P  T   ELA TT       T   P  +      P   
Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 677

Query: 680 QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739
           + P P+            P         P  P+ T P     P      KP    +    
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL---A 734

Query: 740 PITTPPLRST----PRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDP--- 792
           P TT    ST    P PT TP     T  K+P  P + +E    T   ++PT   +P   
Sbjct: 735 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEP-APTTPKEPAPTTPKGTAPTTLKEPAPT 792

Query: 793 ---------LGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA----TEGNATSPPQN 839
                    L     KGP      KP  +P +  ++    PKE A     +   T+P   
Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKP--APTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850

Query: 840 PPTNLTVVT 848
           PPT   V T
Sbjct: 851 PPTTSEVST 859



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 152/604 (25%), Positives = 209/604 (34%), Gaps = 76/604 (12%)

Query: 290  TTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE----TVPRS 345
            TT K PA    + +     + A   T + P   K P     +  P   TP+    T P+ 
Sbjct: 517  TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS-PTTTKEPAPTTPKEPAPTTPKK 575

Query: 346  TKPTTS---SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA-TYDVFSSPTTSDE- 400
              PTT    +     E    +++KP   PT    E +     +TA T     +PTT ++ 
Sbjct: 576  PAPTTPKEPAPTTPKEPAPTTTKKP--APTTP-KEPAPTTPKETAPTTPKKLTPTTPEKL 632

Query: 401  -PEISDSYTATSDRILDSIPPK--TSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
             P   +    T+   L    P+  T  T E+P  T   +  P  P++    T  E  PTT
Sbjct: 633  APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 692

Query: 458  PAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI--------SKSPEPTWTT-PA 508
            P        P+TPK      P  T P         TPK         + + EPT TT   
Sbjct: 693  PKEPA----PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748

Query: 509  PGKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567
            P  T      P  P  P  T  K PAP       P     P P  P+ +P PK     T 
Sbjct: 749  PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTT 807

Query: 568  KPKTS-----PSP----EVSYTTPAPKDVLLPHKPYPEVSQSEP-------APLETRGIP 611
            K  TS     P+P    E + TTP       P KP P   ++ P        P  T+  P
Sbjct: 808  KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE-P 866

Query: 612  FIPMISPSPSQEEL--QTTLEETDQSTQEPF--TTKIPRTTELAKTTQA----PHRFYTT 663
                 SP  S  EL  + T +  + S +EP   TTK P  T+   TT A      R   T
Sbjct: 867  TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926

Query: 664  VRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPP 723
                T+  P +    K+    +       + +T       T +   P + T  +   L P
Sbjct: 927  TPETTTAAPKM---TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 983

Query: 724  NNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFS 783
               T K           ITT  + + P  T  P +R           A+  + +  T   
Sbjct: 984  KVTTTKK---------TITTTEIMNKPEETAKPKDRATNS------KATTPKPQKPTKAP 1028

Query: 784  SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTN 843
              PT    P   PR + P      +   S     +   R    EA     T P Q P + 
Sbjct: 1029 KKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRI--AEAMLQTTTRPNQTPNSK 1086

Query: 844  LTVV 847
            L  V
Sbjct: 1087 LVEV 1090



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 116/509 (22%), Positives = 179/509 (35%), Gaps = 63/509 (12%)

Query: 449 TSPEMQPTTPAPQQTT-SIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTP 507
           TSP      P P   + +I ST KR P+P P + K ++   +  IT + S S     ++ 
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKP-PNKKKTKKVIESEEITEEHSVSENQESSSS 169

Query: 508 APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA 567
           +   +   +++ KI  S      +   K+      K K + + R  + +P PK P  V  
Sbjct: 170 SSSSSSSSTIR-KIKSSKNSAANRELQKKL-----KVKDNKKNRTKK-KPTPKPPV-VDE 221

Query: 568 KPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT 627
                 + +   TTP           + +VS S   P  T   P    I+P PS      
Sbjct: 222 AGSGLDNGDFKVTTPDTSTT-----QHNKVSTS---PKITTAKP----INPRPSLPPNSD 269

Query: 628 TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-----SDKPHIRPGVKQAP 682
           T +ET  +  +  T +   TT   K T    +  TT    T     +    + P  K   
Sbjct: 270 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 329

Query: 683 RPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT 742
           +P+             T K      P  P PT P+     P + T K  +   I S P T
Sbjct: 330 KPT--------PKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAP-T 376

Query: 743 TP----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRF 798
           TP    P  +   PT TP E   T  K+P  P + +E    T    +PT        P+ 
Sbjct: 377 TPKEPAPTTTKSAPT-TPKEPAPTTTKEP-APTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434

Query: 799 KGPHVRYIQKP----DNSPCSITDSVKRFPKEEA--TEGNATSPPQNPPTNLTVVTVEGC 852
             P       P    + +P +  +     PKE A  T+  A + P+ P            
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 494

Query: 853 PSFVILDWEKPLNDTVTE-YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQV 911
           P       ++P   T  E     ++E    + K  +   T    +T +   P T+     
Sbjct: 495 P-------KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547

Query: 912 KPKNPLGEGPVSNTVAFSTESADPRVSEP 940
            PK P    P +      T   +P  + P
Sbjct: 548 TPKEP---SPTTTKEPAPTTPKEPAPTTP 573



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 291  TVKLPASLMFEISDALKTQLAKNETLALP-AESKTPEVEKISARPTTVTPET--VPRSTK 347
            T K PA+   E++   K +  + +    P   +  P++ K +A  T  T E+     +T+
Sbjct: 900  TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQ 959

Query: 348  PTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSY 407
             T+++  D +   + + +   + P  K++   K +     T ++ + P  + +P+     
Sbjct: 960  VTSTTTQDTTPFKITTLKTTTLAP--KVTTTKKTI----TTTEIMNKPEETAKPKDR--- 1010

Query: 408  TATSDRILDSIPPKTSRTLEQPRATLAPSETPFV--------PQKLEIFTSPEMQPTTPA 459
             AT+ +     P K ++  ++P +T  P   P V        P+K+   T PE+ PT+  
Sbjct: 1011 -ATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS-TMPELNPTSRI 1068

Query: 460  PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519
             +      + P + P  K     P+   + G                 A G+T  + L+P
Sbjct: 1069 AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG-----------------AEGETPHMLLRP 1111

Query: 520  KIPLSPEVTHTKPAPKQTPRAPPK-----PKTSPRPRIPQTQPV 558
             +   PEVT   P     PR P +     P  S    I   +PV
Sbjct: 1112 HV-FMPEVT---PDMDYLPRVPNQGIIINPMLSDETNICNGKPV 1151


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  110 bits (276), Expect = 5e-24
 Identities = 162/638 (25%), Positives = 229/638 (35%), Gaps = 97/638 (15%)

Query: 295  PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTP-----ETVPRSTKPT 349
            P    F   ++L  Q +K+        S TP   K +  P+ VTP      T+P    PT
Sbjct: 830  PVEASFLPENSLSFQGSKDSPAT--THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887

Query: 350  TSSALDVSETTLASSEKPWIVPTAKISEDS-KVLQPQTATYDVFSSPTTSDEPEISDSYT 408
             S           ++  P   P   ++  S K  +   A   + +SP+    P    + T
Sbjct: 888  PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT-PPAAT 946

Query: 409  ATSDRILDSIPPKTSRTLEQPR-ATLAPSETPFVPQKLEIFTSPEMQPTTPA--PQQTTS 465
              S        PK       P+ A   P+ TP  P+      SP+  PT PA  P     
Sbjct: 947  PPS--------PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998

Query: 466  IPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPK-IP 522
             P+TP  +  P PP   P   + + A T  PK + +P P  T P+P  +   +  PK  P
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP-PAATPPSPKGSPAATPLPKGAP 1057

Query: 523  LSPEVTHTKP-----------APKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK- 570
             +P  T   P           AP      PP PK  P    P+  P+P  P      PK 
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP--PAATPPSPKG 1115

Query: 571  ----------------TSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIP 614
                            T PSP+    TP PK         P   +   A    +G P  P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175

Query: 615  MISP--------SPSQEELQTTLEETDQSTQEPFTTKIPR--TTELAKTTQAPHRFYTTV 664
              +P        +PS +   TT   T  S +    T  P+   T  A T  +P     T 
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235

Query: 665  RPRTSDK-----PHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPP----------L 709
             P+ +       P    G    P P GA    +  +T P+ K G   PP           
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA--ATPPSLKGGLATPPHKGAPNPAVVT 1293

Query: 710  PPRP------THPRRKPLPPNNVTGKP-GSAGIISSGPITTPPLRSTPRPTGTPLERIET 762
            PP P      + P+  P PP      P GS G        TPP  + P P GTP     T
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 763  DIKQ--PTVPASGEELENITDFSSSPTRETDPLGKPRF--KGPHVRYIQKPDNSPCSITD 818
               +  PT P+S E     T  +++P+ +  P   P    +GP +   +    SP  I  
Sbjct: 1354 PSSKGGPTTPSSKE---GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410

Query: 819  SVKRFPKEEATEGNATSPPQN--PPTNLTVVTVEGCPS 854
            S K+ P    T   A +P +    P  +T V+++  P+
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448



 Score =  110 bits (275), Expect = 7e-24
 Identities = 152/562 (27%), Positives = 205/562 (36%), Gaps = 84/562 (14%)

Query: 316  LALPAESKTPEVEKISARPTT--------VTPETVPRSTKPTTSSALDVSETTLASSEKP 367
            +++  ++K P  +K SA P T        V+P  V  S  P  S +   S+ + A++  P
Sbjct: 799  VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP--VEASFLPENSLSFQGSKDSPATTHSP 856

Query: 368  WIVPTAKISEDSKVLQP-----------QTATYDVFSSPTTSDEPEISDSYTATSDRILD 416
               P+ K +     + P           +T T  V + P   + P       A +  +  
Sbjct: 857  -TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 417  SIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA--PQQTTSIPSTPKRRP 474
            S P K        RAT AP   P  P       SP+  PT PA  P      P+TP  + 
Sbjct: 916  SSPKKA-------RATPAPKGIPASP-------SPKGAPTPPAATPPSPKGGPATPSPKW 961

Query: 475  RPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPK-IPLSPEVTHTKPA 533
             P PP   P  +   G  TP    +P P   TP   K    +  PK  P  P VT   P+
Sbjct: 962  APTPPAATPP-SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT--PPS 1018

Query: 534  PKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK--------TSPSPEVSYTTPAPK 585
            PK +P A P PK +  P    T P PK     T  PK        T PSP+    TP+ K
Sbjct: 1019 PKGSPAATPFPKGASTPPAA-TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077

Query: 586  DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645
                P    P   +  PA    +G P  P  +P   +  L T   +   +T  P  T  P
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT--PAAT--P 1133

Query: 646  RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTR 705
             + +    T  P    TT     +  P    G    P P GA    +  +T P+ K G  
Sbjct: 1134 PSPKGGLATPPPKGAPTT----PAATPPSPKGGLATPPPKGAPTTPA--ATPPSPKGGLA 1187

Query: 706  RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR----STPRPTGTPLERIE 761
             P     PT P   P  P      P   G  ++ P  TPP      +TP P G P     
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-PAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 762  TDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG-PHVRYIQKPDNSPCSITDSV 820
            T       PA+       T  +++P      L  P  KG P+   +  P           
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS---------- 1296

Query: 821  KRFPKEEATEGNATSPPQNPPT 842
               PK     G ATSPP+  PT
Sbjct: 1297 ---PKG----GPATSPPKGAPT 1311



 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 149/566 (26%), Positives = 191/566 (33%), Gaps = 76/566 (13%)

Query: 325  PEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLAS--SEKPWIVPTAKISEDSKVL 382
            PE+ K     +  +P   P  T P T     +S T+  +  +  P   PT      +   
Sbjct: 728  PEIPK-----SVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATAS 782

Query: 383  QPQTATY--------DVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434
               T TY         V  SP T   P    S          + P      L  P   ++
Sbjct: 783  SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS----------AGPDTPIGNLSSP---VS 829

Query: 435  PSETPFVPQKLEIFTSPEMQP-TTPAPQQTTSIPSTPKRRPRPK---PPRTKPERTTSAG 490
            P E  F+P+    F   +  P TT +P      P +PK  P P    P   K        
Sbjct: 830  PVEASFLPENSLSFQGSKDSPATTHSPT-----PPSPKGAPTPSAVTPLSPKGVTLPPKE 884

Query: 491  TITPKISKSPEPTW--TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP 548
            T TP +   P P     TPAP +   +S+      SP+     PAPK  P A P PK +P
Sbjct: 885  TPTPSVVNLPFPKEGPATPAPKQAPALSMTSS---SPKKARATPAPKGIP-ASPSPKGAP 940

Query: 549  RPRI-----PQTQPVPKVPQRVTAKPK-TSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEP 602
             P       P+  P    P+     P  T PSP+    TP+PK    P    P   +  P
Sbjct: 941  TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000

Query: 603  APLETRGIPFIPMIS-PSPSQEELQTTLEE---TDQSTQEPFTTKIPRTTELAK---TTQ 655
            A    +G P  P ++ PSP      T   +   T  +   P     P  T L K   TT 
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060

Query: 656  APHRFYTTVRPRT-SDKPHIRPGVKQAPRPSGADRNVSVD-------STHPTKKPGTRRP 707
            A         P T S K    P     P P G     S         +T P+ K G   P
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 708  PLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPL----RSTPRPTGTPLERIETD 763
            P    PT P   P  P      P   G  ++ P  TPP      +TP P G P     T 
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLATPPPKGAPTTPAATP 1179

Query: 764  IKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG-PHVRYIQKPDNSPCSITDSVKR 822
                   A+       T  +++P      L  P  KG P       P       T S K 
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239

Query: 823  FPKEEATE------GNATSPPQNPPT 842
             P   A        G AT PP+  PT
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPT 1265



 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 142/583 (24%), Positives = 206/583 (35%), Gaps = 127/583 (21%)

Query: 331  SARPTTVTPETVPRSTK-----------PTTSSALDVSETTLASSEKPWIVPTAKISED- 378
            S +    TP   P S K           PTT +A   S     ++  P   PT   +   
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249

Query: 379  SKVLQPQTATYDVFSSPTTSDEPEISDSYT------ATSDRILDSIPPKTSRTLEQPR-A 431
            S    P T       +P  +  P +           A +  ++    PK       P+ A
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309

Query: 432  TLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPS-TPKRRPRPKPPRTKPERTTSA- 489
               P+ TP          SP+  P TP P+   + P+ TP   P PK   T P  T S+ 
Sbjct: 1310 PTPPAATP---------PSPKGSPGTPPPKGAPTPPAVTP---PSPKGTPTLPATTPSSK 1357

Query: 490  -GTITPKISKSPEPTWTTPA-PGKTQFISLKPK-----------------IPLSPEVTHT 530
             G  TP   + P P   TP+  G        PK                 IPLSP+    
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417

Query: 531  KPAPKQTPRAPPKPKTSPRPRIP---QTQPVPKVPQRVTAKPKTSPSPEV-SYTTPAPKD 586
             P  ++    P K   +P    P   +  P    P+   A P +   P + + T P+PK+
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477

Query: 587  VLLPHK----PYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT 642
               P +      P+ + + PAP+   G P +P + PS  +E     +  T  S ++P   
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPM---GAPTLPAVIPSSPKE-----VPATPSSRRDPIA- 1528

Query: 643  KIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIR-----PGVKQAPRPSGADRNVSVDSTH 697
              P  T L+K T A       + P     P  +     P  K+AP    +    S  +  
Sbjct: 1529 --PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586

Query: 698  PTKKPGTRRPP---LPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPL----RSTP 750
            P+   G   P    +PP  T P  K  P               + P  TPP      +TP
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAP---------------TPPAVTPPSPEKGPATP 1631

Query: 751  RPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGK---------PRFKGP 801
             P GTP          P  P+S      + D  +SP   T  +G          P  KGP
Sbjct: 1632 APKGTP-------TSPPVTPSS------LKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678

Query: 802  ----HVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840
                 V     P+++P  IT   ++ P  +  + +ATSPP  P
Sbjct: 1679 TALKEVLVAPAPESTPI-ITAPTRKGP--QTKKSSATSPPICP 1718



 Score = 84.0 bits (206), Expect = 7e-16
 Identities = 117/483 (24%), Positives = 173/483 (35%), Gaps = 54/483 (11%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
            P+  + P +      PT+  P  +P S  P  + A  V+    A+  K  + P       
Sbjct: 1387 PSPKRGPAIPSPKGDPTS--PAVIPLS--PKKAPATPVTREGAATPSKGDLTP------- 1435

Query: 379  SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438
                 P      +  +P TS       + ++  D  L ++ P + +    P+     S  
Sbjct: 1436 -----PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS- 1489

Query: 439  PFVPQKLEIFTSPEMQPTTPA--PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKI 496
               P+K     +P   PT PA  P     +P+TP  R  P  P        +  T+ PK 
Sbjct: 1490 ---PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 497  SKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPR---IP 553
            +  P P  T P+P KT  I    + P +P        P  TP      K +P P+   IP
Sbjct: 1547 ALIP-PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY---KGAPSPKELLIP 1602

Query: 554  QTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYP---EVSQSEPAPLETRGI 610
                 P   +  T    T PSPE    TPAPK         P   + S + PA +  +  
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662

Query: 611  PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD 670
              +P  S     ++  T L+E   +     T  I   T     T+        + P  S 
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722

Query: 671  KPHIR-PGVKQAPRPSGADRNVSVDSTHPTK-KPGTRRPPLPPRPTHPRRKPLPP----- 723
            K   + P    AP P      V  DS+   K K  +  P  P  P  P  K   P     
Sbjct: 1723 KNGSKGPLSTVAPAPL---LPVQKDSSKTAKGKDASHSPKGPLAP--PESKASTPLTAAA 1777

Query: 724  -NNVTGKPGSAGIISS-GPITTPPLRSTPRPTGTPLER--------IETDIKQPTVPASG 773
               V  KP SA + ++  P  + PL  +P PT  P ++        +     +P  PA  
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837

Query: 774  EEL 776
            +EL
Sbjct: 1838 DEL 1840



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 110/475 (23%), Positives = 167/475 (35%), Gaps = 81/475 (17%)

Query: 236  DHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLP 295
            D T+PA  P         KQV  + + K +  +P  AP+G   L   +IP   +     P
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP--APMGAPTLP-AVIPSSPKEVPATP 1520

Query: 296  ASLMFEI-------SDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKP 348
            +S    I       S      LA  E L  PA +  P  +K  A PT       P S + 
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT-VPSPKKTPAIPTPKEAPATPSSKEA 1579

Query: 349  TTSSALDVSETTLASSEKPWIVPTAKISEDSK-------VLQPQTATYDVFSSPT-TSDE 400
            ++  A+  S    A S K  ++P A  S   K       V  P         +P  T   
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS 1639

Query: 401  PEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAP 460
            P ++ S    S     S+  K   T+ Q    L   + P   +++ +  +PE  P   AP
Sbjct: 1640 PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699

Query: 461  QQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPK 520
             +              K P+TK    TS     P I   P+P+    + G    ++  P 
Sbjct: 1700 TR--------------KGPQTKKSSATS-----PPI--CPDPSAKNGSKGPLSTVAPAPL 1738

Query: 521  IPLSPEVTHT------KPAPKQTPRAPPKPKTS------------PRPRIPQTQPVPKVP 562
            +P+  + + T        +PK  P APP+ K S            P+P        P  P
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPK-GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797

Query: 563  QRVTAKPKTSPS--PEVSYTTPAPKDVL-LPHKPYPEVSQSEPAPL-----ETRGIPF-- 612
              +   P   P+  P+  +   +P  VL  P KP     + E  PL      + G+PF  
Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQS 1857

Query: 613  ------------IPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ 655
                        IP+ +PS  Q   +       +S  +    ++        TTQ
Sbjct: 1858 VLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQ 1912



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 88/422 (20%), Positives = 150/422 (35%), Gaps = 44/422 (10%)

Query: 340 ETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSD 399
           ETVP + +       + +   ++S+    +  TA + +    L P  +        + ++
Sbjct: 7   ETVPATEQELPQPQAETAVLPMSSA----LSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62

Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459
           +     S +  +   L+   P++S     P  T AP    F+P  +     P + P   A
Sbjct: 63  QASPFPSPSTIASTPLEVPFPQSSSGTALPLGT-APEAPTFLPNLI----GPPISPAALA 117

Query: 460 ---PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFIS 516
              P    ++  TP            P     +    P +  SP P+      G    +S
Sbjct: 118 LASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP-PSVAVAESGSVITLS 176

Query: 517 L-----KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKT 571
                 +PK  L+   +   P PK TP  P    T P   +    P+  +   V + P+T
Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVT---PMASIQSGVASLPQT 233

Query: 572 SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631
           +P+  ++  +P  KD  +       +S   P  L  +G P  P  + S S + L      
Sbjct: 234 TPTTTLAIASPQVKDTTISSVL---ISPQNPGSLSLKG-PVSPPAALSLSTQSLPVVT-- 287

Query: 632 TDQSTQEPFTTK---IPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGAD 688
           + Q T  P T     I   + LA   Q+       +  +T       P VK         
Sbjct: 288 SSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG-QTGPSALSDPTVK--------- 337

Query: 689 RNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRS 748
             +SVD +       ++R  +PP P+   R  + P  V   P  A  +  GP T   +  
Sbjct: 338 -TISVDHSSTGASYPSQRSVIPPLPS---RNEVVPATVAAFPVVAPSVDKGPSTISSITC 393

Query: 749 TP 750
           +P
Sbjct: 394 SP 395



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 133/607 (21%), Positives = 192/607 (31%), Gaps = 119/607 (19%)

Query: 319 PAESKTPE-VEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISE 377
           P+  K P  +  I+  P+         S  PTTS  L  S            +P + +  
Sbjct: 379 PSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGT 438

Query: 378 DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSE 437
              V+   T    + ++PTT+ E     S   +S  I +  P   +  +  P A   PS 
Sbjct: 439 TPLVV---TNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST 495

Query: 438 TPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRR-PRPKPPRTKPERTTSAG------ 490
              V   L I  SP +    P P+   ++PS+   + P  K  +T P     A       
Sbjct: 496 Q--VATTLRIPVSPPL----PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549

Query: 491 --------TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTK-----PAP--- 534
                   T+ P +  +P+    +P+    Q  S  P+IPLSPE T  K     P P   
Sbjct: 550 GLTTKKDPTVLPLVQAAPK---NSPS---FQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603

Query: 535 --------------------------------------KQTPRAPPKPKTSPRPRIPQT- 555
                                                   T  A P     P    P T 
Sbjct: 604 PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA 663

Query: 556 --------QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET 607
                      P +   V+  PK  P  E + TT         + P     Q+  APL T
Sbjct: 664 KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723

Query: 608 RGI-PFIPMISPSPSQEELQTTLEETDQSTQEPFTTK---IPRTTELAKTTQAPHRFYT- 662
             + P IP   PSPS     T           P T K   I  T+ LA    +P    T 
Sbjct: 724 LVLAPEIPKSVPSPSLPPAGT----------PPGTKKVDGISHTSALAPVASSPKECPTE 773

Query: 663 -TVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP----PRPTHPR 717
            +    T+        +  +P P G   +VS  +  P  K G+  P  P      P  P 
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGV--SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831

Query: 718 RKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELE 777
                P N     GS    ++    TPP   +P+   TP        K  T+P       
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPP---SPKGAPTPSAVTPLSPKGVTLPPKETPTP 888

Query: 778 NITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP--CSITDSVKRFPKEEATEGNATS 835
           ++ +          P  K          +    +SP     T + K  P   + +G  T 
Sbjct: 889 SVVNLPFPKEGPATPAPK------QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942

Query: 836 PPQNPPT 842
           P   PP+
Sbjct: 943 PAATPPS 949


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score =  109 bits (272), Expect = 2e-23
 Identities = 143/515 (27%), Positives = 208/515 (40%), Gaps = 77/515 (14%)

Query: 334  PTTVTPETVPRSTKPTT--SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDV 391
            P  V PE  P S   +T  S    ++E    S++KP    T  I + S   +  T   + 
Sbjct: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKP----TVSIEKPSVTTEKPTVPKEK 590

Query: 392  FSSPTTSDEPEIS-DSYTATSDRILDSIP------PKTSRTLEQPRATLAPSETPFVPQK 444
             + PT  ++P IS +  T  S++   ++P      P    T+   + T+ PSE P +P +
Sbjct: 591  PTIPT--EKPTISTEKPTIPSEK--PNMPSEKPTIPSEKPTILTEKPTI-PSEKPTIPSE 645

Query: 445  -----LEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS 499
                  E  T P  +PTTP  + TTS+        +P  P  KP   T   TI+ +    
Sbjct: 646  KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME---- 701

Query: 500  PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT-SPRPRIPQTQPV 558
             E   +T  P      ++ P+ P  P    T P  K T  +P KP T + +P IP  +P 
Sbjct: 702  -ETIISTEKP------TISPEKPTIPTEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPT 753

Query: 559  --PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP-----YPEVSQSEP-APLETRGI 610
              P+ P   T KP  SP      T P  K  +   KP      P +S  EP  P E   I
Sbjct: 754  ISPEKPTTPTEKPTISPE---KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTI 810

Query: 611  ----PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666
                P IPM  P+   EE  T++EET  ST E  T  + + T   +    P     T +P
Sbjct: 811  STEKPSIPMEKPTLPTEETTTSVEETTIST-EKLTIPMEKPTISTEKPTIP-----TEKP 864

Query: 667  RTSDKPHIRPGVK-----QAPRPSGADRNVSVDS-THPTKKPGTRRPPLPPRPTHPRRKP 720
              S +    P  K     + P     +  +S +  T PT+KP       P +PT    KP
Sbjct: 865  TISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTIS----PEKPTISTEKP 920

Query: 721  LPPNNVTGKPGSAGIISSGPITTPPLRST--PRPTGTPLERIETDIKQPTVPASGEELEN 778
              P      P     IS+  +T P  + T  P     P E+     ++PT+P      E 
Sbjct: 921  TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT-----EK 975

Query: 779  ITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813
            +T  +  PT  T+   KP      +  ++ P  SP
Sbjct: 976  LTIPTEKPTIPTE---KPTIPTEKLTALRPPHPSP 1007


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score =  109 bits (272), Expect = 2e-23
 Identities = 143/515 (27%), Positives = 208/515 (40%), Gaps = 77/515 (14%)

Query: 334  PTTVTPETVPRSTKPTT--SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDV 391
            P  V PE  P S   +T  S    ++E    S++KP    T  I + S   +  T   + 
Sbjct: 535  PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKP----TVSIEKPSVTTEKPTVPKEK 590

Query: 392  FSSPTTSDEPEIS-DSYTATSDRILDSIP------PKTSRTLEQPRATLAPSETPFVPQK 444
             + PT  ++P IS +  T  S++   ++P      P    T+   + T+ PSE P +P +
Sbjct: 591  PTIPT--EKPTISTEKPTIPSEK--PNMPSEKPTIPSEKPTILTEKPTI-PSEKPTIPSE 645

Query: 445  -----LEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS 499
                  E  T P  +PTTP  + TTS+        +P  P  KP   T   TI+ +    
Sbjct: 646  KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME---- 701

Query: 500  PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT-SPRPRIPQTQPV 558
             E   +T  P      ++ P+ P  P    T P  K T  +P KP T + +P IP  +P 
Sbjct: 702  -ETIISTEKP------TISPEKPTIPTEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPT 753

Query: 559  --PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP-----YPEVSQSEP-APLETRGI 610
              P+ P   T KP  SP      T P  K  +   KP      P +S  EP  P E   I
Sbjct: 754  ISPEKPTTPTEKPTISPE---KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTI 810

Query: 611  ----PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666
                P IPM  P+   EE  T++EET  ST E  T  + + T   +    P     T +P
Sbjct: 811  STEKPSIPMEKPTLPTEETTTSVEETTIST-EKLTIPMEKPTISTEKPTIP-----TEKP 864

Query: 667  RTSDKPHIRPGVK-----QAPRPSGADRNVSVDS-THPTKKPGTRRPPLPPRPTHPRRKP 720
              S +    P  K     + P     +  +S +  T PT+KP       P +PT    KP
Sbjct: 865  TISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTIS----PEKPTISTEKP 920

Query: 721  LPPNNVTGKPGSAGIISSGPITTPPLRST--PRPTGTPLERIETDIKQPTVPASGEELEN 778
              P      P     IS+  +T P  + T  P     P E+     ++PT+P      E 
Sbjct: 921  TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT-----EK 975

Query: 779  ITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813
            +T  +  PT  T+   KP      +  ++ P  SP
Sbjct: 976  LTIPTEKPTIPTE---KPTIPTEKLTALRPPHPSP 1007


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  102 bits (254), Expect = 2e-21
 Identities = 139/548 (25%), Positives = 196/548 (35%), Gaps = 75/548 (13%)

Query: 315  TLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAK 374
            T   P    T  V   +  P    PE  P     T ++    S    AS   P     A 
Sbjct: 966  TTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPG---PAL 1022

Query: 375  ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRIL-DSIPPKTSRTLEQPRATL 433
             S+ S+ L P +A     +S  TSD P+ S      + R   D I       L  P +++
Sbjct: 1023 TSDSSRELTPHSA----LTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSV 1078

Query: 434  APSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT 493
             P+ TP           P   P    P++ TS PSTP                +   +++
Sbjct: 1079 VPALTP----------EPSPTPLPTLPKELTSDPSTP----------------SEVTSLS 1112

Query: 494  PKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIP 553
            P   + PE   TTP    T + S   +   SP+     P+P   P   P P  +P P I 
Sbjct: 1113 PTSEQVPESD-TTPDLDTTPYSSTVSEYSRSPD-----PSPSPHPTTTPDPTMAPDP-IT 1165

Query: 554  QTQPVPKVPQRVTAKPKTSPSPE-VSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF 612
               P        T  P T+P P  ++++T  P     P +P+  ++ S   P        
Sbjct: 1166 TLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTP-QPFTTITHSTMIP-------- 1216

Query: 613  IPMISPSP--SQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD 670
             P  +P P  + +   T    T   T  P  T I  +T +   T  P  F TT++P T  
Sbjct: 1217 DPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPF-TTMQPTTMP 1275

Query: 671  KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP---------PRPTHPRRKPL 721
             P   P     P P+      +  + HPT  P     P P         P PT P     
Sbjct: 1276 HPTTTPHPTTTPHPTTTPHPTT--TPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSST 1333

Query: 722  PPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT---PLERIETDIKQPTVPASGEELEN 778
            P       P S G   S P   P ++ +  P  T   P     T  + PT+  S   LE+
Sbjct: 1334 PVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTS-QIPTLEPS-PALES 1391

Query: 779  ITDFSSSPTRETDPLGKPRFKGPHVR---YIQKPDNSPCSITD-SVKRFPKEEATEGNAT 834
                SS+ T   DPL    FK P  +       P ++P S +D +V   P    T     
Sbjct: 1392 SPSRSSTAT-SMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLD 1450

Query: 835  SPPQNPPT 842
             PP +P T
Sbjct: 1451 HPPLDPLT 1458



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 87/330 (26%), Positives = 112/330 (33%), Gaps = 70/330 (21%)

Query: 334  PTTVTPETVPRSTKPTTSSALDVSETT----LASSEKPWIVPTAKISEDSKVLQPQTATY 389
            PTT  P T P  T  T S+ +    TT       +    I       +    +QP T  +
Sbjct: 1176 PTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPH 1235

Query: 390  DVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFT 449
                 PTT+  P      T         IP  T  T  QP  T+ P+  P          
Sbjct: 1236 STTPHPTTTPHPTTITHSTM--------IPDPT--TTPQPFTTMQPTTMPH--------- 1276

Query: 450  SPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509
                  TTP P  T    +TP     P P  T    TT   T TP  + +P P  TTP P
Sbjct: 1277 ----PTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHP--TTPDP 1330

Query: 510  GKTQFI----------------SLKP--KIPLSPEVTHTKPAP----KQTPRAPPKPKTS 547
              T  I                +L P  K  L P++T T PAP     Q P   P P   
Sbjct: 1331 SSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALE 1390

Query: 548  PRPRIPQTQPVPKVPQRVTAKPKTSPSPEV-----------SYTTPAPKDVLLP------ 590
              P    T            KP  S SP +           S  T +P  +L P      
Sbjct: 1391 SSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLD 1450

Query: 591  HKPYPEVSQSEPAPLETRGIPFIPMISPSP 620
            H P   ++   P P ++ G P  P ++P+P
Sbjct: 1451 HPPLDPLTLG-PTPGQSPG-PHGPCVAPTP 1478



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 89/378 (23%), Positives = 126/378 (33%), Gaps = 85/378 (22%)

Query: 484  ERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKI--PLSPEVTHTKPAPKQTPRAP 541
            E T +AG + P +        TT +PG    + +      P  P      P P  T  AP
Sbjct: 950  EGTPTAGKLGPTLGAG-----TTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAP 1004

Query: 542  PKPKTSPRPRIPQTQPVPKV---------PQRVTAKPKTSPSPEVSYTTPAPKDVLLPHK 592
            P P  SP P      P P +         P        TS +P+ S  TP P       +
Sbjct: 1005 PTP--SPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPAS-----R 1057

Query: 593  PYPEVSQSEPA-PLETRGIPFIPMISPSPSQEELQTTLEE--TDQSTQEPFTTKIPRTTE 649
              P++  + P   L T     +P ++P PS   L T  +E  +D ST    T+  P + +
Sbjct: 1058 TNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQ 1117

Query: 650  LAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPL 709
            + ++   P    T      S+         ++P PS         S HPT  P    P +
Sbjct: 1118 VPESDTTPDLDTTPYSSTVSE-------YSRSPDPS--------PSPHPTTTPD---PTM 1159

Query: 710  PPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTV 769
             P P                     I +  P  TP   +TP PT TP          PT 
Sbjct: 1160 APDP---------------------ITTLNPTVTPHFPTTPHPTTTP---------HPT- 1188

Query: 770  PASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEAT 829
                     IT  +  P   T P  +P     H   I  P  +P   T           T
Sbjct: 1189 --------TITHSTMIPDPTTTP--QPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTT 1238

Query: 830  EGNATSPPQNPPTNLTVV 847
                T+P     T+ T++
Sbjct: 1239 PHPTTTPHPTTITHSTMI 1256



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 80/321 (24%), Positives = 116/321 (36%), Gaps = 39/321 (12%)

Query: 260  VTHKDSAKSPEKAPLGGVILVH-LIIPGLNETTVKLPASLMFEISDALKTQLAKNET--- 315
            +TH      P   P     + H  +IP  + TT   P + M   +    T      T   
Sbjct: 1190 ITHSTMIPDPTTTPQPFTTITHSTMIP--DPTTTPQPFTTMQPTTTPHSTTPHPTTTPHP 1247

Query: 316  LALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375
              +   +  P+        TT+ P T+P  T  TT         T  ++  P   P   +
Sbjct: 1248 TTITHSTMIPDPTTTPQPFTTMQPTTMPHPT--TTPHPTTTPHPT--TTPHPTTTPHPTM 1303

Query: 376  SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAP 435
            + D       T T D    PTT+  P   D    +S  ++ ++   TS   E    TLAP
Sbjct: 1304 TPDPTTTPYPTTTPD----PTTTPHPTTPDP---SSTPVITTVSLPTSLGTELSSPTLAP 1356

Query: 436  SETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP- 494
            +  P +         P++  T PAP  +TS    P   P P    + P R+++A ++ P 
Sbjct: 1357 TVKPSL--------HPQLTFTAPAPHTSTS--QIPTLEPSPAL-ESSPSRSSTATSMDPL 1405

Query: 495  -----KISKSPEPTWTTP---APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT 546
                 K  +S  P  T P    P     +++ P   LSP        P       P P  
Sbjct: 1406 STEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQ 1465

Query: 547  SPRPRIPQTQPVPKVPQRVTA 567
            SP P  P   P P  P RV A
Sbjct: 1466 SPGPHGPCVAPTP--PVRVMA 1484



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 44/190 (23%), Positives = 67/190 (35%), Gaps = 29/190 (15%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASS-----EKPWIVPTA 373
            P  + TP+        TT  P T P  T P  SS   ++  +L +S       P + PT 
Sbjct: 1299 PHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTV 1358

Query: 374  KISEDSKVL----QPQTATYDV--------------FSSPTTSDEPEISDSYTATSDRIL 415
            K S   ++      P T+T  +               SS  TS +P  ++ +     +  
Sbjct: 1359 KPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSP 1418

Query: 416  DSIPPKT------SRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPST 469
            +  PP T      S     P   L+P+  P     L+  T       +P P      P+ 
Sbjct: 1419 NLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTP 1478

Query: 470  PKRRPRPKPP 479
            P R    +PP
Sbjct: 1479 PVRVMACEPP 1488


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 129/514 (25%), Positives = 183/514 (35%), Gaps = 62/514 (12%)

Query: 314  ETLALPAESKTPEVEKISARP----TTVTPETVPRSTKPTTSSALDVSET-----TLASS 364
            E +  P    T   E  +  P    TTVTP   P ST+ TT + +  + T     T   +
Sbjct: 1295 ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGT 1354

Query: 365  EKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSR 424
            + P   P    +  +    P T T    ++P T+    ++ + T T  +   S P  T+ 
Sbjct: 1355 QTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTSTPITTTT 1412

Query: 425  TLEQ---PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRT 481
            T+     P  T  P+ TP          +P   PT       T+I +T    P P P  T
Sbjct: 1413 TVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469

Query: 482  KPERTTSAGTITPKISKSPEPTWT-TPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPR 539
            +   TT   T T  ++ +P PT T TP P           I  +  VT T  P   QTP 
Sbjct: 1470 QTPTTTPI-TTTTTVTPTPTPTGTQTPTP---------TAITTTTTVTPTPTPTGTQTPT 1519

Query: 540  APPKPKT---SPRPRIPQTQPVPKVPQRVTAKPKTSPSP---EVSYTTPAPKDVLLPHKP 593
            + P   T   +P P    TQ     P   T     +P+P   +   TTP      +   P
Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579

Query: 594  YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT--TLEETDQSTQEPFTTKIP-----R 646
             P  +Q+    L T      P  +P+ ++    T  T   T  +T  P  T+ P      
Sbjct: 1580 TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIS 1639

Query: 647  TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706
            TT     T  P    T     TS  P I       P P  +    S  ++ P  +  T  
Sbjct: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAP-IAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 1698

Query: 707  PPLPP----RPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIET 762
              LPP      T P   P  P   +G          G   +PP  +T  P GTP     T
Sbjct: 1699 STLPPAIEMTSTAPPSTPTAPTTTSG----------GHTLSPPPSTTTSPPGTPTRGTTT 1748

Query: 763  DIKQPTVPASGEELENITDFSSSPTRETDPLGKP 796
                   P++ +     T  +S+ T    PL  P
Sbjct: 1749 GSSSAPTPSTVQ-----TTTTSAWTPTPTPLSTP 1777



 Score = 83.6 bits (205), Expect = 9e-16
 Identities = 140/560 (25%), Positives = 197/560 (35%), Gaps = 83/560 (14%)

Query: 335  TTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED---SKVLQPQTATYD- 390
            TT+T  T P +   TT++    S T L+++ K   + +  I+ED   S        T+D 
Sbjct: 1170 TTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG 1229

Query: 391  VFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETP----FVP---- 442
            V  +P   +   + D + +     L+ +  K     +     +  +E       +P    
Sbjct: 1230 VCGAPEDIECRSVKDPHLS-----LEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFC 1284

Query: 443  -------QKLEIFTSPEMQPTTPAPQQT-TSIPSTPKRRPRPKPPRTK---PERTTSAGT 491
                   Q  E  T P    TT     T T I +T    P P P  T+   P   T+  T
Sbjct: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344

Query: 492  ITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHT-KPAPKQTPRAPPKPKT---S 547
            +TP           TP P  TQ  +  P I  +  VT T  P   QTP   P   T   +
Sbjct: 1345 VTP-----------TPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1392

Query: 548  PRPRIPQTQPVPKVPQRVTAKPKTSPSP---EVSYTTPAPKDVLLPHKPYPEVSQSEPAP 604
            P P    TQ     P   T     +P+P   +   TTP      +   P P  +Q+ P P
Sbjct: 1393 PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQA-PTP 1451

Query: 605  LETRGIPFIPMISPSPSQEELQT------------TLEETDQSTQEPFTTKIPRTTELAK 652
                 I     ++P+P+    QT            T   T   TQ P  T I  TT +  
Sbjct: 1452 ---TAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTP 1508

Query: 653  T-----TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKP-GTRR 706
            T     TQ P    T +   T+  P   P   Q P P+      +V    PT  P GT+ 
Sbjct: 1509 TPTPTGTQTPTS--TPITTTTTVTPTPTPTGTQTPTPTPISTTTTVT---PTPTPTGTQT 1563

Query: 707  PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-TPPLRSTPRPTGTPLERIETDIK 765
            P   P  T     P P    T  P +  I ++  +T TP   ST   T TP+    T   
Sbjct: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA 1623

Query: 766  QPTVPASGE----ELENITDFSSSPTRETDPLGKPRFKG----PHVRYIQKPDNSPCSIT 817
             PT   +       +   T  + +PT  T   G P          +     P  S    T
Sbjct: 1624 TPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQT 1683

Query: 818  DSVKRFPKEEATEGNATSPP 837
                  P  E+T   +T PP
Sbjct: 1684 SRSTSSPLTESTTLLSTLPP 1703



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 92/360 (25%), Positives = 127/360 (35%), Gaps = 42/360 (11%)

Query: 311  AKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIV 370
            A   T      + TP       +  T TP T   +  PT +     + T  A +    + 
Sbjct: 1448 APTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT 1507

Query: 371  PT-AKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQP 429
            PT       +    P T T  V  +PT    P  + + T T      ++ P  +     P
Sbjct: 1508 PTPTPTGTQTPTSTPITTTTTVTPTPT----PTGTQTPTPTPISTTTTVTPTPT-----P 1558

Query: 430  RATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTK-----PE 484
              T  P+ TP          +P   PT      T  I +T    P P P  TK     P 
Sbjct: 1559 TGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615

Query: 485  RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAP---KQTPRAP 541
             TT+  T TP  + +  PT    +   T   +  P    +   THT  AP     T   P
Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP 1675

Query: 542  PK---PKTSPRPRIPQTQPV-------PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH 591
            P+   P+TS     P T+         P +    TA P T  +P    TT +    L P 
Sbjct: 1676 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP----TTTSGGHTLSP- 1730

Query: 592  KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT-KIPRTTEL 650
               P  + + P    TRG       +P+PS   +QTT       T  P +T  I RTT L
Sbjct: 1731 ---PPSTTTSPPGTPTRGTTTGSSSAPTPS--TVQTTTTSAWTPTPTPLSTPSIIRTTGL 1785



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 79/301 (26%), Positives = 115/301 (38%), Gaps = 65/301 (21%)

Query: 319  PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLAS-----SEKPWIVPTA 373
            P  ++TP    I+   TT+TP   P STK TT + +  + T  A+     ++ P ++P  
Sbjct: 1581 PTGTQTPTTVLITTT-TTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP-- 1637

Query: 374  KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATL 433
             IS  + V    T T      PT +    I++    TS+   +S  P+TSR+   P  T 
Sbjct: 1638 -ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE--LTTSNPPPESSTPQTSRSTSSP-LTE 1693

Query: 434  APSETPFVPQKLEIF-TSPEMQPTTPA-----------PQQTTSIPSTPKR-----RPRP 476
            + +    +P  +E+  T+P   PT P            P  TTS P TP R         
Sbjct: 1694 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 1753

Query: 477  KPPRTKPERTTSAGTITPKISKSPEPTWTTP-------------------APGKT----- 512
              P T    TTSA T TP    +P    TT                    APG+      
Sbjct: 1754 PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGT 1813

Query: 513  -----QFISLKPKIPLS------PEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV 561
                  F++      L       P      P P ++   P KP ++P    P T+P P+ 
Sbjct: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKP-PEC 1872

Query: 562  P 562
            P
Sbjct: 1873 P 1873


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 143/623 (22%), Positives = 218/623 (34%), Gaps = 100/623 (16%)

Query: 284 IPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 343
           +P  +     LPA+L    S  L T L     LA P+ S  P ++ + + P T   +  P
Sbjct: 317 VPPPDNAATPLPATL--PPSPPLATPLP----LAPPSPSAPPSLQTLPSPPATPPSQAPP 370

Query: 344 RSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEI 403
             T P   +   +          P I     ++  S    P         + T+   P +
Sbjct: 371 SMTTPPMQAPPSLQTI-------PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 404 SDSYTATSDRILDSIPPKTSRTLEQP-RATLAPSETPFVPQKLEIFTSPEMQ-------- 454
             +++      L   P +T  +L  P R    P ++P +   L +  SP +Q        
Sbjct: 424 QATHS-----FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478

Query: 455 ----PTTPAPQQTTSIPSTPKRRPR-PKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP 509
               P T  P Q  S  S     P+ P      P   T +    P + ++P  + TTP  
Sbjct: 479 PLSSPLTIHPLQALS--SLASHSPQAPLSSLIMPPLETQSSLAPPSL-QTPPASLTTPPL 535

Query: 510 GKTQFISLKP----KIPLSPEVTHTKPAPKQTP-RAPPKPKTSPRPRIPQT--QPVPKVP 562
                ++  P      PL+     T P P   P +APP P T+P P  P +   P P+ P
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595

Query: 563 QRVTAKP-KTSPSPEVS-YTTP---APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMIS 617
             + + P +  PSP +S   TP   AP  + LP    P    + P        P  P+ +
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP--------PLSPLAT 647

Query: 618 PSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPG 677
           PSP                Q PF+       +   +  A      +  P +   P +   
Sbjct: 648 PSPQAPNALAV-----HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702

Query: 678 VKQAPRPSGADRNVSVDSTHPTKKP-------------GTRRPPLPPRPTHPRRKP---- 720
             Q P    A   +S  +T P + P                 PP+ P  T P R P    
Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA 762

Query: 721 LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780
            PP  V   P ++  +   P+  PP ++ P     PL+ +      P+ PAS        
Sbjct: 763 APPLQVPPSPPAS--LPMSPLAKPPPQAPPALATPPLQAL------PSPPAS---FPGQA 811

Query: 781 DFSSSPTRETDPLGKPRFKGPHV---RYIQKPDNSPCSITDSVKRFPKEEATEGNATSP- 836
            FS S +    PL  P  + P V     +Q P + P S T    R P     + + + P 
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871

Query: 837 --------PQNPPTNLTVVTVEG 851
                   P  PP+     T+ G
Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSG 894



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 126/547 (23%), Positives = 186/547 (34%), Gaps = 64/547 (11%)

Query: 317 ALPAESKTPEVEKISARPTTVTPETVPRS--TKPTTSSALDVSETTLASSEKPWIVPTAK 374
           A  A  + P  E+         PE+ PR+  T+   +S+ + +    AS       P AK
Sbjct: 49  AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGER-APPAK 107

Query: 375 ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434
            +    V  P  A+      P       IS   T    +  ++ P +++ +    R T  
Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSG 166

Query: 435 PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP 494
           P  TP  P       SP M   + A      +P  P    RP+PP   P ++ S+ +   
Sbjct: 167 P--TPGTP-------SPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHS 216

Query: 495 KISKSPEPTWTTPAPGKTQFISLKP----KIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP 550
               SP       A G  Q  + +       PLS     + P+ + TPRAP  P + P+P
Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA-RSGPSARGTPRAPAHP-SQPKP 274

Query: 551 RIPQTQPVPKV-PQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609
           +  Q    P+V P R  A P   P       TP+P       +P P        P +   
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA--RPVP--------PPDNAA 324

Query: 610 IPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTS 669
            P    + PSP    L T L     S   P + +   +      +QAP        P  +
Sbjct: 325 TPLPATLPPSPP---LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP--------PSMT 373

Query: 670 DKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGK 729
             P   P   Q   P        +   H    P  + PP P          L     T  
Sbjct: 374 TPPMQAPPSLQTIPP--------IQVPHSLTSPSLQAPPSP--------LALSSLQATTS 417

Query: 730 PGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRE 789
            GS  + ++    T   R T     +P     T    P + A    L       +S +  
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP-LSLPASPPLQTSLSPA 476

Query: 790 TDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPP--QNPPTNLTVV 847
             PL  P    P         +SP +   S+   P E  +   + +PP  Q PP +LT  
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS---SLAPPSLQTPPASLTTP 533

Query: 848 TVEGCPS 854
            +E  PS
Sbjct: 534 PLENLPS 540



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 104/463 (22%), Positives = 150/463 (32%), Gaps = 83/463 (17%)

Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEI--FTSPEMQPTTPAPQQTTSIPSTPKRRPRP 476
           PP T   L    A  A    P   +   I   T PE  P        T    T  R P  
Sbjct: 37  PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP----TRSAGTSSRNPAS 92

Query: 477 KPPRT-KPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPK 535
           +PP + + ER   A   +P    SP     T  PG      L+    +S E T    A  
Sbjct: 93  RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR----ISAEET---VARG 145

Query: 536 QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYP 595
           +   AP +   S   R   + P P  P    A+   +   EV    PAP     P    P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 596 EVSQSEPAPLETRGIPFIPMISPSPSQEE-------LQTTLEETDQSTQEPFTTKIPRTT 648
             S S  +   T          PSP+          LQ     +  S+  P ++      
Sbjct: 206 RKSVSSASEHSTT--------EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257

Query: 649 ELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPP 708
               T +AP       +P+      +RP     PR   A          P   P +  P 
Sbjct: 258 SARGTPRAPAH---PSQPKPKGLQALRPPQVTPPRKDAA----------PALGPLSSSPL 304

Query: 709 LPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITT------------PPLRSTPRPTGTP 756
             P P+  + +P+PP +    P  A +  S P+ T            P L++ P P  TP
Sbjct: 305 ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364

Query: 757 LERIETDIKQPTVPASGEELENITDFS-----SSPTRETDP-------------LGKPRF 798
             +    +  P + A    L+ I         +SP+ +  P             LG P  
Sbjct: 365 PSQAPPSMTTPPMQAP-PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 799 KGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPP 841
           +  H      P  +  S+T   +           A++PP +PP
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSR----------PASTPPDSPP 456



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 89/399 (22%), Positives = 132/399 (33%), Gaps = 59/399 (14%)

Query: 475 RPKPPRTKPERTTSA---GTITPKISKSPEPTW-TTPAP----GKTQFISLKPKIPLSPE 526
           R K       RT +A   G +TP+   SP P    TPA     G    +  KP    +  
Sbjct: 5   RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 527 VTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKD 586
           +      P+  PRA P        R P ++P         A  +   +P    T+P P  
Sbjct: 65  IGGAT-IPESAPRAGPTRSAGTSSRNPASRP--------PASGRGERAPPAKNTSPGPVS 115

Query: 587 VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPR 646
                 P      + P PL  +G+          S EE     + T+   +   +    R
Sbjct: 116 -----SPGRASGTTRPGPLGQKGLRI--------SAEETVARGKATEAPKRSALSAGARR 162

Query: 647 TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRP--SGADRNVSVDSTHPTKKPGT 704
            T                R   ++    RP     PRP   G  ++VS  S H T +P  
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222

Query: 705 RRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDI 764
                       RR+P     +  +P S  + SS    + P RS P   GTP  R     
Sbjct: 223 AA----------RRRPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGTP--RAPAHP 269

Query: 765 KQPTVPASGEELENITDFSSSPTRE----------TDPLGKPRFKGPHVRYIQKPDNSPC 814
            QP      + L+ +     +P R+          + PL  P   G   R +  PDN+  
Sbjct: 270 SQP----KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 815 SITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCP 853
            +  ++   P        A   P  PP+  T+ +    P
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 82/320 (25%), Positives = 132/320 (41%), Gaps = 22/320 (6%)

Query: 417 SIPPKTSRTLEQPRATLA---PSETPF--VPQKLEIFTSPEMQPTTPAPQQT--TSIPST 469
           S PP+ S T   P A+     P E P   +P+ L +    E  P +P P+++  +  P +
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509

Query: 470 PKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSP--EV 527
               P  + P + PE +  +  +   +S  PE +  +P   ++       ++P SP  E 
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA 569

Query: 528 THTKPAPKQTPRAPPKPKTSPRPRIPQTQPV-PKVPQRVTAKPKT----SPSPEVSYTTP 582
           +   P P+++P +PP P+ SP    P+   + P   +   + P      SP PE S  +P
Sbjct: 570 SRLSPPPEESPMSPP-PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628

Query: 583 APKDVLLPHKPYPEVSQSEPAPLETR--GIPFIPMISPSPSQEELQTTLEETDQSTQEPF 640
            P+D   P  P PE S   P P  +R   +P +  +SP P +  L    EE+  S   P 
Sbjct: 629 PPED--SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS-PPPE 685

Query: 641 TTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700
            +++    E + T+  P    +   P   D     P  +    P   +  +   S  P  
Sbjct: 686 ASRLSPPPEDSPTSPPPED--SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743

Query: 701 KPGTRRPPLPPRPTHPRRKP 720
            P    P L PRP  P   P
Sbjct: 744 SPRPEEPHLSPRPEEPHLSP 763



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 134/581 (23%), Positives = 201/581 (34%), Gaps = 89/581 (15%)

Query: 319  PAESKT---PEVEKISA----RPTTVTPETVPRSTKPTTS-SALDVSETTLAS-SEKPWI 369
            P ES T   PE  ++S      PT+  PE  P S  P  S  +L + E+ L    E+P +
Sbjct: 675  PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734

Query: 370  VPTAKISEDSKVLQPQTATYDVFSSPTT------SDEPEISDSYTATSDRILDSIP--PK 421
             P +    +   L P+     +   P        ++EP +S       +  L ++P  P 
Sbjct: 735  CPRS----EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ---PEEPCLCAVPEEPH 787

Query: 422  TSRTLEQPRATLAPSETPFVPQKLEIFTSP--EMQPTTPAPQQTTSIPST--PKRRPRPK 477
             S   E P  +  P E    PQ  E   SP  E    +P P+++   P +  P   PRP+
Sbjct: 788  LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847

Query: 478  PPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTH-------- 529
                 PE       ++P+  K PE     PAP +        +  LSP +          
Sbjct: 848  ESHLSPE--LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905

Query: 530  --TKPAPKQTPRAPP-KPKTSPRPRIPQTQPVPKVP-QRVTAKPKTSPSPEVSYTTPAPK 585
                P P++ P +P  +P  SP+   P   P P  P     A P  SP  E+ Y   A  
Sbjct: 906  PPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKG 965

Query: 586  D-----------VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQ 634
            D           +  P  P PE + ++P P+    +P  P     P+   L   L     
Sbjct: 966  DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP---- 1021

Query: 635  STQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVD 694
                      P+ + L + +  P        P     P +   V     P G    VS +
Sbjct: 1022 ----------PQCSPLLQHSLVPQ----NSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067

Query: 695  S------THPTKKPGTRRPPLPPRPTHPRRKPLPPNNV---TGKPGSAGIISSGPITTP- 744
            +      T    +P    P L P  T P   P+   +    +  P        G  T P 
Sbjct: 1068 AELHEMETEKVSEP--ECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPL 1125

Query: 745  ----PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSP-TRETDPLGKPRFK 799
                   S P P  TP   + +++K   V    EEL  +T     P  ++T   G P  +
Sbjct: 1126 DGIDAPGSQPEPGQTP-GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEE 1184

Query: 800  GPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840
                R    P       +D V         + +A+ P   P
Sbjct: 1185 QEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEP 1225



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 82/374 (21%), Positives = 127/374 (33%), Gaps = 43/374 (11%)

Query: 455  PTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAP-GKTQ 513
            PTTPA   T++           KPP        S G +  K+         +  P G   
Sbjct: 2129 PTTPAGLSTSADGFL-------KPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAP 2181

Query: 514  FISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSP 573
               L+P+ P +P      P+P   P  PP    S RP   Q       P        ++P
Sbjct: 2182 AYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP 2241

Query: 574  SPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSP---SQEELQTTLE 630
             P +    P+  ++ +P  P     ++             P++SP P   S++ L+   E
Sbjct: 2242 DPFLKPRCPSLDNLAVPESPGVGGGKASE-----------PLLSPPPFGESRKALEVKKE 2290

Query: 631  ETDQSTQE------PFTTKIPRTTEL-AKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPR 683
            E   S+         F       T L     + P  F   + PR S      PG+   P+
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350

Query: 684  -PSGADRNVSVDSTHP-TKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPI 741
             P  A        +HP   +PG+   P    P  PR +P PP +    P  +  + S P 
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS--LPSDPF 2408

Query: 742  TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEEL--ENITDFSSSPTRETDPLGKPRFK 799
            +  P         +P  +  +       P S E      +T    SP   + P  +P+ +
Sbjct: 2409 SRVP--------ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460

Query: 800  GPHVRYIQKPDNSP 813
             P     + P   P
Sbjct: 2461 DPFAPLHKPPRPQP 2474



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 105/457 (22%), Positives = 155/457 (33%), Gaps = 84/457 (18%)

Query: 306  LKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSE 365
            LK +    + LA+P   ++P V    A    ++P     S K     AL+V +  L +S 
Sbjct: 2245 LKPRCPSLDNLAVP---ESPGVGGGKASEPLLSPPPFGESRK-----ALEVKKEELGASS 2296

Query: 366  KPWIVPTAKI----SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPK 421
              +  P        S  + +   +  T DVF +P T                      P+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT----------------------PR 2334

Query: 422  TSRTLEQ-PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPR 480
             S+   Q P   L P E P       +  SP   P    P   T   + P   PRP+PP 
Sbjct: 2335 ASQVEPQSPGLGLRPQEPP---PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP- 2390

Query: 481  TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRA 540
              PE   +     P  S   +P    PA  ++Q  S  P  P         P+P      
Sbjct: 2391 -PPESCCA----LPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445

Query: 541  PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600
             P P + P  R     P  + P     KP     PEV++   +     L    +P    +
Sbjct: 2446 SPDPYSRPPSR-----PQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPA 2500

Query: 601  EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660
             PA      +P                       S Q P   + P T      T +P RF
Sbjct: 2501 GPAGELHAKVP-----------------------SGQPPNFVRSPGTGAFV-GTPSPMRF 2536

Query: 661  YTTVRPRTSDKPHIRPGVKQ--APRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRR 718
                 P+   +P ++P V Q   P P G + +     T    KP +    +     HP  
Sbjct: 2537 ---TFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT--LGKPQSTNYTVATGNFHPSG 2591

Query: 719  KPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT 755
             PL P+  +G  G +  +S  P+  P +   P P G+
Sbjct: 2592 SPLGPS--SGSTGESYGLS--PLRPPSVLPPPAPDGS 2624



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 97/406 (23%), Positives = 146/406 (35%), Gaps = 90/406 (22%)

Query: 435  PSETPF-----VPQKLEIFTSPEMQPTTPAP----------------------QQTTSIP 467
            PS+ PF      P +    T+P   P  P+P                      +  T+ P
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231

Query: 468  STPKRRPRPKPPRTKPERTTSAGTITPKI-----SKSPEPTWTTPAPGKTQFISLKPKIP 522
             TP+ +P    P  KP   +      P+       K+ EP  + P  G+++      K  
Sbjct: 2232 GTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEE 2291

Query: 523  L---SPEV--------------THTKPAPKQTP---RAPPKPKTSP-RPRIPQTQPVPKV 561
            L   SP                TH      +TP   +AP  P+ S   P+ P     P+ 
Sbjct: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351

Query: 562  PQRVTAKPKTSPS-PEV----SYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI 616
            P    A   + PS P++    SYT P  +  L P +P P   +S  A L  R +P  P  
Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP-RPQPPPPESCCA-LPPRSLPSDP-F 2408

Query: 617  SPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRP 676
            S  P+  + Q+       S+Q P T + P + E    +    RF +   P    +P  RP
Sbjct: 2409 SRVPASPQSQS-------SSQSPLTPR-PLSAEAFCPSPVTPRFQS---PDPYSRPPSRP 2457

Query: 677  -------GVKQAPRPSGADRNVSVDS-THPTKKPGTRRPPLPPRPTHPRRKPLP---PNN 725
                    + + PRP   +      S  H +   G     LP  P       +P   P N
Sbjct: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517

Query: 726  VTGKPGSAGIISSGPITTPPLRST-PRPTGTPLERIETDIKQPTVP 770
                PG+   +     T  P+R T P+  G P   ++  + QP +P
Sbjct: 2518 FVRSPGTGAFVG----TPSPMRFTFPQAVGEP--SLKPPVPQPGLP 2557



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 69/326 (21%), Positives = 102/326 (31%), Gaps = 33/326 (10%)

Query: 532 PAPKQTPRAPP---------KPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 582
           P P  TP   P         +PK      +   QP    P +  AKP      ++     
Sbjct: 375 PEPGDTPTDEPDALYVACQGQPKGG---HVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLE 431

Query: 583 APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT 642
           AP +  +P  P PE S   P P E+         SP P    L    EE   S   P   
Sbjct: 432 APLNEEMPLLPPPEESPLSPPPEES-------PTSPPPEASRLSPPPEELPASPL-PEAL 483

Query: 643 KIPRTTELAKTTQAPHRFYTTVRPRTS-----DKPHIRPGVKQAPRPSGADRNVSVDSTH 697
            + R  E +  +  P     +  P +S     ++  + P  +  P P+            
Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543

Query: 698 PTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPL 757
           P   P    P  PP    P   P   + ++  P         P++ PP  S   P     
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPP------EESPMSPPPEESPMSPPPEAS 597

Query: 758 ERIETDIKQPTVPASGEELENITDFSS--SPTRETDPLGKPRFKGPHVRYIQKPDNSPCS 815
                  + P  P   E   +    +S  SP  E  P+  P  + P     +    SP  
Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657

Query: 816 ITDSVKRFPKEEATEGNATSPPQNPP 841
           +   +   P+E          P +PP
Sbjct: 658 VVSRLSPPPEESPLSPPPEESPTSPP 683



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 8/103 (7%)

Query: 382  LQPQTATYDVFSSPTTSDEPEISDSYTATSDRI----LDSIPPKTSRTLEQPRATLAPSE 437
            L+ Q     +    + + EP    SYT     +    L + PP+       P + LAPS 
Sbjct: 4869 LKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP---SPPPSPLAPSP 4925

Query: 438  -TPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPP 479
             +P     +E+ T P  +P  P+P    S P + + +PR +PP
Sbjct: 4926 ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 526  EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 585
            +V      P + P  PP P  +P P  P T+P+ ++P    A+P   PSP    ++P   
Sbjct: 4902 DVRQLSAPPPEEPSPPPSP-LAPSPASPPTEPLVELPTEPLAEPPV-PSPLPLASSPESA 4959

Query: 586  DVLLPHKPYPEVSQSEPAPLE 606
                  +P  E   S P  L+
Sbjct: 4960 RPKPRARPPEEGEDSRPPRLK 4980



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 94/394 (23%), Positives = 138/394 (35%), Gaps = 80/394 (20%)

Query: 426  LEQPRATLAPSET--------PFVPQK-LEIFTSP------------EMQPTTPA-PQQT 463
            L Q R  L+P +         P +P K L+ F+SP            E     PA   + 
Sbjct: 3978 LNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEA 4037

Query: 464  TSIPSTPKRRPRPKPPRTKPER-TTSAGTITPKISKSPEPTWTTPAPG-KTQFISLKPKI 521
            T  PST   +  P    T PE   T  G + P +S   +     P P  +   + L+P +
Sbjct: 4038 TEGPST--HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPL 4095

Query: 522  PLSPEV-------------THTKPAPKQTPRAPPKPKTSPRPRIP-------QTQPVPKV 561
             L  +              +H +     +  A   P    +P +         TQ +   
Sbjct: 4096 RLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGP 4155

Query: 562  PQRVTAKP---KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAP---LETRGI----P 611
             Q +  +P    T P P      P P  VL   +  P V           + +G+    P
Sbjct: 4156 QQPMLERPMQNNTGPQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP 4209

Query: 612  FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDK 671
             +  +SP   Q++LQ  L +  Q  Q     + P   E    T +P +     +P+    
Sbjct: 4210 QLRHLSPQ-QQQQLQALLMQR-QLQQSQAVRQTPPYQEPGTQT-SPLQGLLGCQPQLGGF 4266

Query: 672  PHIRPGVKQ----APRPSGADRNVSVD---STHPTKKPGTRRPPLPPRPTHPRRKPLPPN 724
            P  + G  Q     PRP G  R  +     ST P   P    PP P  P  P+R    P+
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP-PSSPQEPKRPSQLPS 4325

Query: 725  NVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLE 758
              +  P  A +    P T P    TP+P G  LE
Sbjct: 4326 PSSQLPTEAQL----PPTHP---GTPKPQGPTLE 4352



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 61/255 (23%), Positives = 89/255 (34%), Gaps = 31/255 (12%)

Query: 532  PAPKQTPRAPPKP---KTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588
            P P+  PR P  P    T P        P P  PQ    +P   PSP     T A     
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE-PKRPSQLPSPSSQLPTEAQLPPT 4339

Query: 589  LPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTT 648
             P  P P+    EP P              SP+  +L  TL        +P    +  T 
Sbjct: 4340 HPGTPKPQGPTLEPPPGRV-----------SPAAAQLADTLFSKGLGPWDP-PDNLAETQ 4387

Query: 649  ELAKTTQAP---HRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTR 705
            +  +++  P    +    V P  S +  I+   ++ P   GA       +  P   PGT 
Sbjct: 4388 KPEQSSLVPGHLDQVNGQVVPEAS-QLSIKQEPREEPCALGAQSVKREANGEPIGAPGTS 4446

Query: 706  RPPLPPRPTHPR-----RKPLPPNNV---TGKPGSAGIIS--SGPITTPPLRSTPRPTGT 755
               L   P         +K L   NV   TG+ GS G+ +  +G I +       +  GT
Sbjct: 4447 NHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGR-GSEGLRAEINGHIDSKLAGLEQKLQGT 4505

Query: 756  PLERIETDIKQPTVP 770
            P  + +   ++P  P
Sbjct: 4506 PSNKEDAAARKPLTP 4520



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 79/374 (21%), Positives = 126/374 (33%), Gaps = 64/374 (17%)

Query: 429  PRATLAPSETPFVPQKLEIFTSPEMQ------------PTTPAPQQTTSIPSTPKRRPRP 476
            P ++L P+  P V QK+    +P  +             +  A + T+ + S       P
Sbjct: 4622 PPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALP 4681

Query: 477  KPPRTKPER--------TTSAGTITPKISKSPEPTWTTPAPG---------KTQFISLKP 519
             PP  + E         + S  +I P  + SPE      AP          + +  +L P
Sbjct: 4682 TPPHNQTEDVRMESDEDSDSPDSIVP--ASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739

Query: 520  KIPLSPEVT-----HTKPAPKQTPRAPPK-PKTSPRPRIPQTQPVPKVPQRVTAKPKTSP 573
             IPL P  +      TKP        P K P T+          V        AK     
Sbjct: 4740 VIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799

Query: 574  SPEV----SYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629
               V    S   P   +VL P  P    + +EP   E  G        P   ++ L+   
Sbjct: 4800 MVAVAELLSMKIPNSYEVLFPESPAR--AGTEPKKGEAEG--------PGGKEKGLEGKS 4849

Query: 630  EETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADR 689
             +T     + F   +P  T  ++           +     + P   P  + +   + ++ 
Sbjct: 4850 PDTGPDWLKQFDAVLPGYTLKSQLD--------ILSLLKQESPAPEPPTQHSYTYNVSNL 4901

Query: 690  NVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLP--PNNVTGKPGSAGIISSGPITTPPLR 747
            +V   S  P ++P     PL P P  P  +PL   P     +P    + S  P+ + P  
Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP---PVPSPLPLASSPES 4958

Query: 748  STPRPTGTPLERIE 761
            + P+P   P E  E
Sbjct: 4959 ARPKPRARPPEEGE 4972



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 5/71 (7%)

Query: 702  PGTRRPPLP-----PRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTP 756
            PG +  PL      PRP  P R P PP  ++  P    +  + P ++P     P    +P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326

Query: 757  LERIETDIKQP 767
              ++ T+ + P
Sbjct: 4327 SSQLPTEAQLP 4337


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 162/715 (22%), Positives = 245/715 (34%), Gaps = 74/715 (10%)

Query: 249  PITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKT 308
            P+T   Q   + T  D    P      G           +     +P S M  +S    T
Sbjct: 2368 PVTTYSQAGSSPTTADDTSMPTSTYSEG-----------STPLTSVPVSTMPVVSSEAST 2416

Query: 309  QLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKP---TTSSALDVSETTLASSE 365
                    + P  + T    + S+ PTT    ++P S      T  +++ VS T + SSE
Sbjct: 2417 HSTTPVDTSTPVTTST----EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSE 2472

Query: 366  KPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRT 425
               +  T   +       P T + +  SSPTT+++  +  S  +    +L SIP  T+  
Sbjct: 2473 AGTLSTTPVDTST-----PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPV 2527

Query: 426  LEQPRATLA----PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRT 481
                 +TL+     S +P V    EI +S      T  P  T S  STP    R  P  T
Sbjct: 2528 ASPEASTLSTTPVDSNSPVV-TSTEISSSATSAEGTSMPTSTYSEGSTPL---RSMPVST 2583

Query: 482  KPERTTSAGTI--TPKISKSP--EPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQT 537
            KP  ++ A T+  TP  +  P    T T+ +P   +  S+    P     + T       
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTM 2643

Query: 538  PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH--KPYP 595
            P A  +  T     +  T+ +       ++ P T+    +  +TP  +   L +      
Sbjct: 2644 PVASSEASTLSTTPV-DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTT 2702

Query: 596  EVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ 655
             ++ SE + L T  +     ++ S       TT E T      P     P T+ L  T  
Sbjct: 2703 LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLP 2762

Query: 656  APHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTH 715
                  +TV     D           P  +  +      S+ PT    T  P   P  T 
Sbjct: 2763 VASSEASTVSTTAVD--------TSIPVTTSTEA-----SSSPTTAEVTSMPTSTPSETS 2809

Query: 716  PRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEE 775
                 +P N+       AG +S+ P+ T    STP  T T      T  +   VP S   
Sbjct: 2810 TPLTSMPVNHTPVASSEAGTLSTTPVDT----STPVTTSTKASSSPTTAEGIVVPISTAS 2865

Query: 776  LENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNA-- 833
             E  T  +S P   T     P            P ++   +T S +        EG +  
Sbjct: 2866 -EGSTLLTSIPVSTT-----PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMP 2919

Query: 834  TSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQ 893
             S P    T LT + V   P  V       L+ T  +       +   S    + + T+ 
Sbjct: 2920 ISTPSEVSTPLTSILVSTVP--VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSM 2977

Query: 894  TFSTV-ENLKPNTSYEFQVKP-----KNPLGEGP--VSNTVAFSTE-SADPRVSE 939
              ST  E   P TS      P      + L   P   S  V  STE S+ P  +E
Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE 3032



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 182/780 (23%), Positives = 268/780 (34%), Gaps = 148/780 (18%)

Query: 292  VKLPASLMFEISDALK------TQLAKNETLAL---PAESKTPEVEK--ISARPTTVTPE 340
            + +P S   E    LK      T +A +E   L   P +S +P V    +S+ PT     
Sbjct: 1443 ISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1502

Query: 341  TVPRSTKPTTSSALD---VSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTT 397
            ++  ST    S+AL    VS TT+ASSE   +  T  ++       P T      SSPTT
Sbjct: 1503 SIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST-----PVTTYSQASSSPTT 1557

Query: 398  SDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
            +D   +  S  +     L S+P  T   +     TL  S TP +  K ++  S E   +T
Sbjct: 1558 ADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL--STTP-IDSKTQVTASTEASSST 1614

Query: 458  PAPQQT-------------TSIP--STPKRRPRPKPPRTKPERTTSAGTITPKISKSPEP 502
             A   +             TSIP  +TP   P      T P  + S    + ++S SP P
Sbjct: 1615 TAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTP 1674

Query: 503  TWTTPAP------GKTQFISL----KPKIPLSPEVTHTKPAPKQTP-----RAPPKPKTS 547
               T  P      G+T   S+     P    +     T P    TP      A   P TS
Sbjct: 1675 AEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTS 1734

Query: 548  PRPRIPQTQPVPKVPQRVTAKPKTSP--SPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPL 605
                +P + P        +    T+P  S E S  +  P D   P     E + S P   
Sbjct: 1735 EGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEAT-SSPTTA 1793

Query: 606  ETRGIPFIPM---ISPSPSQEELQTTLEETDQST--QEPFTTKIPRTTELAKT------- 653
            E   IP   +   ++P  S     T +  ++ ST    P  +  P  T  A +       
Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1853

Query: 654  -----TQAPHR----------FYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV----D 694
                 T  P              TTV    ++     P V   P  + A  + S      
Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913

Query: 695  STHPTKKPGTRRPPL--------------------------PPRPTHPRRKPLPPN-NVT 727
            S+ PT  P   RPPL                           P  T+ +    P   + T
Sbjct: 1914 SSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGT 1973

Query: 728  GKPGSAGIISSGPITTPP-------------LRSTPRPTGTPLERIETDIKQPTVPASGE 774
              P  A    S P+T+ P             L +TP  T TP          PT  A G 
Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTT-AGGT 2032

Query: 775  ELENITDFSSSPTRETDPL-GKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNA 833
             ++     +S+P+  T PL G P         +   + +  S T    +     +TE ++
Sbjct: 2033 SIQ-----TSTPSERTTPLAGMP----VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASS 2083

Query: 834  TSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDT-VTEYEVISRENGSFSGKNKSIQMTN 892
            ++  +     ++  + EG P    +    PL+ T V   E  +         +  I  T 
Sbjct: 2084 SATAEGSSMTISAPS-EGSPLLTSI----PLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138

Query: 893  QTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTV----AFSTESADP-RVSEPVSAGRDA 947
             + S +     +         + PL   PVS TV    A ST S  P   S PV+   +A
Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198



 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 167/737 (22%), Positives = 254/737 (34%), Gaps = 112/737 (15%)

Query: 261  THKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPA 320
            T  +++ SP  A  G  + +     G    T  L ++L    S+A        +T ++P 
Sbjct: 2725 TSAEASSSPTTAE-GTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT-SIPV 2782

Query: 321  ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALD---VSETTLASSEKPWIVPTAKISE 377
             + T    + S+ PTT    ++P ST   TS+ L    V+ T +ASSE   +  T   + 
Sbjct: 2783 TTST----EASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTS 2838

Query: 378  DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA--P 435
                  P T +    SSPTT++   +  S  +    +L SIP  T+       +TL+  P
Sbjct: 2839 T-----PVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893

Query: 436  SETPF-VPQKLEIFTSPEMQPTTPAPQQTTSIPSTP------------------------ 470
             +T   V    E  +SP     T  P  T S  STP                        
Sbjct: 2894 VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV 2953

Query: 471  -KRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTH 529
              R P           TT+ GT  P  +     T  T     T  ++      LS     
Sbjct: 2954 DTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPAD 3013

Query: 530  TKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSP--SPEVSYTTPAPKDV 587
            T      +  A   P T+    IP + P        +    T+P   PE S  +  P D 
Sbjct: 3014 TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDS 3073

Query: 588  LLPHKPYPEVSQSEPAPLETRGIPF------------IPMISPSPSQEELQTTLEETDQS 635
              P     EVS S P P E   +P             +P +S +P      +TL  T   
Sbjct: 3074 NSPVVTSTEVS-SSPTPAEGTSMPISTYSEGSTPLTGVP-VSTTPVTSSAISTLSTTPVD 3131

Query: 636  TQEPFT--------------TKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQA 681
            T  P T              T +P +T    +T   +   +T+   +S+   +       
Sbjct: 3132 TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTL----SAT 3187

Query: 682  PRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPI 741
            P  +      S ++T  T   GT  P   P         +P +N       A I+S    
Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILS---- 3243

Query: 742  TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGP 801
            TTP   +TP  T T         +  ++P S    E  T  +S P   T           
Sbjct: 3244 TTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPS-EGSTPLTSMPVSTTT---------- 3292

Query: 802  HVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWE 861
                +   + S  S T +    P    ++  ++SPP    T++        P+    +  
Sbjct: 3293 ----VASSETSTLSTTPADTSTPVTTYSQA-SSSPPIADGTSM--------PTSTYSEGS 3339

Query: 862  KPL-NDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKN----- 915
             PL N + +   V+S E  + S        T  T ST  +L P T+    +   +     
Sbjct: 3340 TPLTNMSFSTTPVVSSEASTLSTTPVDTS-TPVTTSTEASLSPTTAEGTSIPTSSPSEGT 3398

Query: 916  -PLGEGPVSNTVAFSTE 931
             PL   PVS T   S+E
Sbjct: 3399 TPLASMPVSTTPVVSSE 3415



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 169/740 (22%), Positives = 263/740 (35%), Gaps = 113/740 (15%)

Query: 260 VTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKT-QLAKNETLAL 318
           +T  +++ SP  A  G  I       G    T   PAS M   +  + T  +   +T  L
Sbjct: 307 ITSTEASSSPTTAE-GTSIPTSTYTEGSTPLT-STPASTMPVATSEMSTLSITPVDTSTL 364

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
              S  P     +A  T++   T+   + P T+  + VS   +ASSE      T+ I  D
Sbjct: 365 VTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTN--MPVSTILVASSEAS---TTSTIPVD 419

Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438
           SK     T   +  SSPTT+++  I+ S  +     L S+P  T+       + L  S T
Sbjct: 420 SKTFV--TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNL--STT 475

Query: 439 PFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISK 498
           P V  K ++ TS E   + P  +  +   STP     P         T+ + +  P  S 
Sbjct: 476 P-VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTP--------LTSMSVSTMPVASS 526

Query: 499 SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQT--PRAPPKPKTSPRPRIPQTQ 556
                 TTP    T        +  S E + +   P+ T  P + P   ++P   +P + 
Sbjct: 527 EASTLSTTPVDTST-------PVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVST 579

Query: 557 PVPKVPQRVTAKPKTSP---------SPEVSYTTPAPKDVLLPHKPYPE----------- 596
            +  V     +   T+P         S E S ++   +   +P   Y E           
Sbjct: 580 RL--VVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVS 637

Query: 597 ---VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKT 653
              V+ SE + L T  +     ++ S       TT E T   T        P T+    T
Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697

Query: 654 TQAPHRFYTTVRPRTSD-KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPR 712
           T       +T+     D    +    + +  P+ AD      ++ PT  P     PL   
Sbjct: 698 TLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTAD-----GASMPTSTPSEGSTPL--- 749

Query: 713 PTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPAS 772
                         T  P S  +++S   +T  L +TP  T T +         PT    
Sbjct: 750 --------------TSMPVSKTLLTSSEAST--LSTTPLDTSTHITTSTEASCSPTT-TE 792

Query: 773 GEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGN 832
           G  +   T    SP   + P+         +  +  P+ S  S T      P   +TE +
Sbjct: 793 GTSMPISTPSEGSPLLTSIPVS--------ITPVTSPEASTLSTTPVDSNSPVTTSTEVS 844

Query: 833 ATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTN 892
           ++  P    +  T    EG      +    P++ T+     IS    S +  + S  +TN
Sbjct: 845 SSPTPAEGTSMPTSTYSEGRTPLTSM----PVSTTLVATSAIS--TLSTTPVDTSTPVTN 898

Query: 893 QTFSTVENLKPNTSYEFQVKPKNPLGEG-------PVSNTVAFSTE----SADP-RVSEP 940
              ST     P TS E    P +  GEG       P S T   S+E    SA P   S P
Sbjct: 899 ---STEARSSPTTS-EGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTP 954

Query: 941 VSAGRDAIWTERPFNSDSYS 960
           V+   +A  T  P  ++  S
Sbjct: 955 VTTSTEA--TSSPTTAEGTS 972



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 165/724 (22%), Positives = 249/724 (34%), Gaps = 108/724 (14%)

Query: 295  PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR----STKPTT 350
            P +   E S +  T       ++ P+E  TP    +++ P + TP  +P     ST P  
Sbjct: 3017 PVTTSTEASSSPTTAEGTGIPISTPSEGSTP----LTSIPVSTTPVAIPEASTLSTTPVD 3072

Query: 351  SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDE-PEISDSYTA 409
            S++  V+ T ++SS  P    +  IS  S+   P T    V ++P TS     +S +   
Sbjct: 3073 SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGV-PVSTTPVTSSAISTLSTTPVD 3131

Query: 410  TSDRILDSI----PPKTSRTLEQPRATLAPSETP--FVPQKLEIFTSPEMQPTTPAPQQT 463
            TS  +  S      P TS     P +T +   TP  ++P    +  S E    +  P  T
Sbjct: 3132 TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDT 3191

Query: 464  TSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPL 523
            ++  +T                TT+ GT  P  + S   T  T  P     +S  P    
Sbjct: 3192 STPVTTSTE---------ATSSTTAEGTSIPTSTPSEGMTPLTSVP-----VSNTPVASS 3237

Query: 524  SPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR----VTAKP---KTSPSPE 576
               +  T P    TP       +S  P    T      P      +T+ P    T  S E
Sbjct: 3238 EASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSE 3297

Query: 577  VSYTTPAPKDVLLPHKPYPEVSQSEP------APLETRGIPFIPM----ISPSPSQEELQ 626
             S  +  P D   P   Y + S S P       P  T      P+     S +P      
Sbjct: 3298 TSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEA 3357

Query: 627  TTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSG 686
            +TL  T   T  P TT    T      T A      T  P     P     V   P  S 
Sbjct: 3358 STLSTTPVDTSTPVTTS---TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSS 3414

Query: 687  ---------ADRNVSVD-----STHPTKKPGTRRPPLPPRPTHPRRKPL---PPNNVTGK 729
                      D N  V      S+ PT   GT    LP   T     PL   P +     
Sbjct: 3415 EVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT---SLPTSTTSEGSTPLSIMPLSTTPVA 3471

Query: 730  PGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPAS--GEELENITDF----- 782
               A  +S+ P+ T    STP  T +P     T  +  ++P S  GE    +T+      
Sbjct: 3472 SSEASTLSTTPVDT----STPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527

Query: 783  ----SSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQ 838
                S + T  T P+    F    V    +  +SP ++  +  R      +EG+++    
Sbjct: 3528 PVASSEASTLSTTPVDSNTF----VTSSSQASSSPATLQVTTMRM--STPSEGSSSLTTM 3581

Query: 839  NPPTNLTVVTVEGCPSFVILDWEKPL------NDTVTEYEVISRENGSFSGKNKSIQMTN 892
               +     +    PS   +D   P+      N T T  EVI+    + S  +  + +  
Sbjct: 3582 LLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP 3641

Query: 893  QTFSTVENLKPNTSYEFQVKPKNP------LGEGPVS---NTVAFST--ESADPRVSEPV 941
             + ++V   +  T+    V    P      +   PV+    T+   T  E + P  + PV
Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701

Query: 942  SAGR 945
            S  R
Sbjct: 3702 STTR 3705



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 151/758 (19%), Positives = 256/758 (33%), Gaps = 95/758 (12%)

Query: 249  PITIIKQVIQNVTHKDSAKSPEKAPLGGV-------ILVHLIIPGLNETTVKLPASLMFE 301
            P+T   +   + T  D A  P   P  G        +   L+      T    P      
Sbjct: 718  PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTH 777

Query: 302  ISDALKTQLAKNET--LALPAESKTPEVEKISARPTTVTPETVPR----STKPTTSSALD 355
            I+ + +   +   T   ++P  + +     +++ P ++TP T P     ST P  S++  
Sbjct: 778  ITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPV 837

Query: 356  VSETTLASSEKP---WIVPTAKISED---------SKVLQPQTATYDVFSSPTTSDEPEI 403
             + T ++SS  P     +PT+  SE          S  L   +A   + ++P  +  P  
Sbjct: 838  TTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVT 897

Query: 404  SDSYTATSDRILD--SIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQ 461
            + +   +S    +  S+P  T      P  ++  S TP V  +    ++  +  +TP   
Sbjct: 898  NSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPV-T 956

Query: 462  QTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP----KISKSPEPTW-TTPAPGKTQFIS 516
             +T   S+P        P + P   T+  T TP     ++ S   T  TTP    T    
Sbjct: 957  TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNT---- 1012

Query: 517  LKPKIPLSPEVTHTKPAP----KQTPRAPPKPKTSPRPRIP--QTQPVPKVPQRVTAKPK 570
                 PL+     + P P       P + P   ++P  R+P   T         ++  P 
Sbjct: 1013 -----PLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA 1067

Query: 571  TSPSPEVSYTTPAPKDVL-----LPHKPYPE--------------VSQSEPAPLETRGIP 611
             + +P  +Y+  +          +P   Y E              V  SE + L T  + 
Sbjct: 1068 DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVD 1127

Query: 612  FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD- 670
                ++ S       TT E T   T  P     P  +    TT        T+     D 
Sbjct: 1128 TSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS 1187

Query: 671  KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKP 730
            K  +    + +  P  A+      ++ PT  PG R  PL   P   R  P+  +      
Sbjct: 1188 KTQVATSTEASSPPPTAE-----VTSMPTSTPGERSTPLTSMPV--RHTPVASS------ 1234

Query: 731  GSAGIISSGPI-TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENI---TDFSSSP 786
              A  +S+ P+ T+ P+ ++   + +P     T +   T       L +I   T   +SP
Sbjct: 1235 -EASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293

Query: 787  TRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTV 846
               T        KGP V       N   S     +      +T     +P  + P N T+
Sbjct: 1294 EASTLLTTPVDTKGPVV-----TSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTL 1348

Query: 847  VTVEGCP--SFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPN 904
            V        S   +D   P+  +       +   G+    +   + T    S   +  P 
Sbjct: 1349 VASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPV 1408

Query: 905  TSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVS 942
             S E       P+       T A +T S  P  +E +S
Sbjct: 1409 VSSEASTLSATPVDTSTPGTTSAEATSS--PTTAEGIS 1444



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 125/486 (25%), Positives = 181/486 (37%), Gaps = 52/486 (10%)

Query: 308  TQLAKNETLAL---PAESKTPEV--EKISARPTTVTPETVPRSTKPTTSSALD---VSET 359
            T +A +ET  L   PA++ TP     + S+  TT    ++P ST    S+ L    VS  
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTR 1111

Query: 360  TLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIP 419
             + SSE   +  T     D+ +  P T + +  SSPTT++   I  S  +     L S+P
Sbjct: 1112 LVVSSEASTLSTTPV---DTSI--PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 1166

Query: 420  PKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRP--- 476
              T+  +     TL  S TP V  K ++ TS E     P  + T+   STP  R  P   
Sbjct: 1167 VSTTLVVSSEANTL--STTP-VDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTS 1223

Query: 477  KPPRTKPERTTSAGTI--TPKISKSPEPT--WTTPAPGKTQFISLKPKIPLSPEVTHTKP 532
             P R  P  ++ A T+  +P  + +P  T   T+ +P   +  SL P    S   T    
Sbjct: 1224 MPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSL-PTSTTSEGSTLLTS 1282

Query: 533  APKQTPRAPPKPKTSPRPRIPQTQPV-PKVPQRVTAKPKTSPSPE--VSYTTPAPKDVLL 589
             P  T        TSP      T PV  K P   + +  +SP+P    S  T    +   
Sbjct: 1283 IPVSTTLV-----TSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRT 1337

Query: 590  PHKPYPE----VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645
            P    P     V+ S  + L T  +     ++ S       TT E T      P     P
Sbjct: 1338 PLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP 1397

Query: 646  RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTR 705
             T+    TT       +T+     D     PG   A   S            PT   G  
Sbjct: 1398 LTSIPVSTTPVVSSEASTLSATPVDTS--TPGTTSAEATSS-----------PTTAEGIS 1444

Query: 706  RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPI--TTPPLRSTP-RPTGTPLERIET 762
             P   P       K +P +N       A  +S+ P+   +P + ST    + TP E    
Sbjct: 1445 IPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504

Query: 763  DIKQPT 768
             I  P+
Sbjct: 1505 AISTPS 1510



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 170/737 (23%), Positives = 245/737 (33%), Gaps = 112/737 (15%)

Query: 294  LPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISAR--PTTVTPETVPRSTKPTTS 351
            +P S     S A+ T          P ++ TP      AR  PTT    ++P ST    S
Sbjct: 2166 MPVSTTVVASSAIST------LSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGS 2219

Query: 352  SALDVSETTLASSEKPWIVPTAKISEDSKV--LQPQTATYDVFSSPTTSDEPEISDSYTA 409
            +      T++  S  P +   A     + V    P T + +  SSPTT++   I  S  +
Sbjct: 2220 TPF----TSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 2275

Query: 410  TSDRILDSIPPKTSRTLEQPRATLA----PSETPFVPQKLEIFTSPEMQPTTPAPQQTTS 465
                 L SIP   +       +TL+     S TPF     E  + P     T  P  T+S
Sbjct: 2276 EGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFT-TSTEASSPPPTAEGTSMPTSTSS 2334

Query: 466  IPSTPKRRPRPKPP-----RTKPERTTSAGTITP-----KISKSPEPTWTTPAPGKTQF- 514
              +TP  R            T    TT A T TP     +   SP     T  P  T   
Sbjct: 2335 EGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394

Query: 515  ---------ISLKPKIPLSPEVTHTKPAPKQTP-----RAPPKPKTSPRPRIPQTQPVPK 560
                     +S  P +        T P    TP      A   P T+    IP + P   
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454

Query: 561  VPQRVTAKPKTSP--SPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF------ 612
                 +    T+P  S E    +  P D   P     E S S P   E   +P       
Sbjct: 2455 TTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEAS-SSPTTAEDIVVPISTASEG 2513

Query: 613  ------IPMISPSPSQEELQTTLEETDQSTQEPF--TTKIPRTTELAKTTQAPHRFY--- 661
                  IP +S +P      +TL  T   +  P   +T+I  +   A+ T  P   Y   
Sbjct: 2514 STLLTSIP-VSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEG 2572

Query: 662  -TTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV-----DSTHPTKKPGTRRPPLPPRPTH 715
             T +R        +          +  D ++ V      S+ PT    T  P   P    
Sbjct: 2573 STPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVS 2632

Query: 716  PRRKPLPPNNVTGKPGSAGIISSGPITTPPLRST--------------PRPTGTPLERIE 761
                 +  + +      A  +S+ P+ T  L +T                PT TP ER  
Sbjct: 2633 TSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERST 2692

Query: 762  --TDIKQPTVPASGEELENIT----DFSSSPTRETDPLGKP-RFKGPHVRYIQKPDNSP- 813
              T+I   T   +  E   ++    D S+  T   +    P   +G  +R     D S  
Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTP 2752

Query: 814  -CSITDSVKRFPKEEATEGNATSPPQNPP--------TNLTVVTVEGCPSFVILDWEKPL 864
              SI  S       EA+  + T+   + P        ++ T   V   P+    +   PL
Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812

Query: 865  ND-TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG--- 920
                V    V S E G+ S        T  T ST  +  P T+ E  V P +   EG   
Sbjct: 2813 TSMPVNHTPVASSEAGTLSTTPVDTS-TPVTTSTKASSSPTTA-EGIVVPISTASEGSTL 2870

Query: 921  ----PVSNTVAFSTESA 933
                PVS T   S+E++
Sbjct: 2871 LTSIPVSTTPVASSEAS 2887



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 142/663 (21%), Positives = 222/663 (33%), Gaps = 80/663 (12%)

Query: 296 ASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE--TVPRSTKP---TT 350
           +S M  +S A         +L    +  TP      A  +  TPE  T+P+ST     T 
Sbjct: 158 SSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTP 217

Query: 351 SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTAT 410
            +++  S   +ASSE   ++ T       ++  P T +    SSPTT++ P +S+S  + 
Sbjct: 218 LTSMPASTMKVASSEAITLLTTPV-----EISTPVTISAQASSSPTTAEGPSLSNSAPSG 272

Query: 411 SDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-ST 469
               L  +P      +    +TL  S TP     + + TS E   ++P   + TSIP ST
Sbjct: 273 GSTPLTRMPLSVMLVVSSEASTL--STTP-AATNIPVITSTEAS-SSPTTAEGTSIPTST 328

Query: 470 PKRRPRP---KPPRTKPERTTSAGT--ITPKISKSPEPTWTTPA--PGKTQFISLKPKIP 522
                 P    P  T P  T+   T  ITP  + +   T T P+  P   +  S+     
Sbjct: 329 YTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTS-T 387

Query: 523 LSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 582
           LS   T     P  T        ++       ++         ++ P T+    ++ +TP
Sbjct: 388 LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447

Query: 583 APKDVLLPHKPY--PEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPF 640
           +     L   P     V+ SE + L T  +     ++ S        T E     T  P 
Sbjct: 448 SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507

Query: 641 TTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTK 700
               P T+    T        +T+     D         +A   S      S+    PT 
Sbjct: 508 EGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSI----PTS 563

Query: 701 KPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI 760
            P     PL   P   R       + T              TTP   +T   T +     
Sbjct: 564 TPSEGSTPLTNMPVSTRLVVSSEASTTS-------------TTPADSNTFVTTSSEASSS 610

Query: 761 ETDIKQPTVPAS--GEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITD 818
            T  +  ++P S   E    IT  S S T                  +   + S  S T 
Sbjct: 611 STTAEGTSMPTSTYSERGTTITSMSVSTT-----------------LVASSEASTLSTTP 653

Query: 819 SVKRFPKEEATEGNATSPPQNPPTNLTVVTVEG--CPSFVILDWEKPLNDTVTEYEVISR 876
                P   +TE  ++S            T EG   P+    +   PL        +++ 
Sbjct: 654 VDSNTPVTTSTEATSSS-----------TTAEGTSMPTSTYTEGSTPLTSMPVNTTLVAS 702

Query: 877 ENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQV------KPKNPLGEGPVSNTVAFST 930
              S          T  T ST  +  P T+    +      +   PL   PVS T+  S+
Sbjct: 703 SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762

Query: 931 ESA 933
           E++
Sbjct: 763 EAS 765



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 162/725 (22%), Positives = 241/725 (33%), Gaps = 124/725 (17%)

Query: 285  PGLNETTVKLPASLMFEISDALK------TQLAKNETLAL---PAESKTPEVEKISARPT 335
            P + E T  LP S   E S  L       T +A +E   L   P ++ TP     ++ PT
Sbjct: 3440 PTIAEGT-SLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVT---TSSPT 3495

Query: 336  TVTPETVPRSTKPTTSSA--------LDVSETTLASSEKPWIVPTAKISEDSKVLQPQTA 387
              +P T   ++ PT+++         + VS T +ASSE   +  T           P  +
Sbjct: 3496 NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT-----------PVDS 3544

Query: 388  TYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVP--QKL 445
               V SS   S  P      T       +     T+  L     T + + TP  P   + 
Sbjct: 3545 NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRS 3604

Query: 446  EIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTW 504
               T+     +TP P +  ++P STP     P      P  TTS  TI+   + S  P  
Sbjct: 3605 TPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPL--TIMPVSTTSV-TISEAGTASTLPVD 3661

Query: 505  T-TPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQ-PVPKVP 562
            T TP    TQ +S  P  P    +    P+   TP       T+   R+  ++      P
Sbjct: 3662 TSTPVITSTQ-VSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTT---RVTSSEGSTLSTP 3717

Query: 563  QRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQ 622
              VT+ P T+ +  +S +       +    P    +      + T  +   P  S +PS 
Sbjct: 3718 SVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPE-SSTPSI 3776

Query: 623  EELQTTLEETDQSTQEPFTTKIPRTTEL-AKTTQAPHRFYTTV--------RPRTSDKPH 673
              + T++  T  S      T +  TT +   TT       TTV         P  +    
Sbjct: 3777 PSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836

Query: 674  IRPGVKQAP-------------------------RPSGADRNVSVDSTHPTKKPGTRRPP 708
              PG    P                           S     + V +T PT  PG     
Sbjct: 3837 TPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS 3896

Query: 709  LPP---------------RPTHPRRKPLPPNNVT--GKPGSAGIISSGPITTPPLRSTPR 751
             PP                PT P    +  + +T    PG+   I S P+T+      P 
Sbjct: 3897 TPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPA 3956

Query: 752  PTG---TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQK 808
             TG   TP+    T++  P+  +S       T  S S T+E        F  P +     
Sbjct: 3957 TTGAVSTPV-ITSTELNTPSTSSSS------TTTSFSTTKE--------FTTPAMTTAAP 4001

Query: 809  PDNSPCSITDSVKRFPKEEATEGNAT-SPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDT 867
                  S   S  R      T   +T S    P T+ +V T    PS      E     T
Sbjct: 4002 LTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSS-----ESSRPST 4056

Query: 868  VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVA 927
            +T + +      +F   + S   T    ST  N +  T+   + KP       P   T A
Sbjct: 4057 ITSHTI----PPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTA 4112

Query: 928  FSTES 932
              T +
Sbjct: 4113 VPTNT 4117



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 95/399 (23%), Positives = 144/399 (36%), Gaps = 73/399 (18%)

Query: 285  PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344
            P   E T  +P S   E S  L T L    ++  P+E+ T                    
Sbjct: 3795 PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEAST-------------------L 3835

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTT------- 397
            ST P  +S   ++ T   S   P  V T +IS  S+   P T      + PT+       
Sbjct: 3836 STPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIA 3895

Query: 398  SDEP-EISDSYTATSDRI-LDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP 455
            S  P + S ++T ++D     +IP  T+ ++        P  T F+P      ++ ++ P
Sbjct: 3896 STPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFP 3955

Query: 456  TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFI 515
             T     T  I ST    P           +TS+ + T   S + E  +TTPA       
Sbjct: 3956 ATTGAVSTPVITSTELNTP-----------STSSSSTTTSFSTTKE--FTTPA------- 3995

Query: 516  SLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSP 575
             +    PL+     T P+   TPR   +  T+    +  T   P     VT +P T PS 
Sbjct: 3996 -MTTAAPLTYVTMSTAPS---TPRTTSRGCTTSASTLSATS-TPHTSTSVTTRPVT-PSS 4049

Query: 576  EVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQS 635
            E S  +      + P   +P    S P        P     S + + E + T    T  S
Sbjct: 4050 ESSRPSTITSHTIPP--TFPPAHSSTP--------PTTSASSTTVNPEAVTTMTTRTKPS 4099

Query: 636  TQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHI 674
            T+   TT  P  T  A  T       TT++   +  P +
Sbjct: 4100 TR---TTSFPTVTTTAVPTN------TTIKSNPTSTPTV 4129



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 112/483 (23%), Positives = 165/483 (34%), Gaps = 70/483 (14%)

Query: 422 TSRTLEQPRATLAPSETPFVPQKLEIFTS--PEMQPT--TPAPQQTTSIPSTPKRRPRPK 477
           TS  + +PR  L+ S  P +       TS  P +  T  TP   +TTS  ++      P 
Sbjct: 72  TSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPS 131

Query: 478 PPRTKPERTTSAGTITPKISKSPEP-------TWTTPAPGKTQFISLKPKIPLSPEVTHT 530
                   TT  GT  P  + S E          T P P    + SL  K+ +S  +T +
Sbjct: 132 STEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTS 191

Query: 531 KPAPKQ--TPRAPPKPK------TSPRPRIPQ--------------TQPVP-----KVPQ 563
             A     TP +   PK      ++P   +P               T PV       +  
Sbjct: 192 TQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISA 251

Query: 564 RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPE--VSQSEPAPLET----RGIPFIPM-- 615
           + ++ P T+  P +S + P+     L   P     V  SE + L T      IP I    
Sbjct: 252 QASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTE 311

Query: 616 ISPSPSQEE-----LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD 670
            S SP+  E       T  E +   T  P +T    T+E++  +  P    T V   TS 
Sbjct: 312 ASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLV--TTST 369

Query: 671 KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKP 730
           +P   P   +A   S     +S  ST  T  P +         +     P+         
Sbjct: 370 EPSSLPTTAEA--TSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTA 427

Query: 731 GSAGIISSGPIT---TPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT----DFS 783
             A   SS P T   T    STP    TPL    T +   T P +  E  N++    D  
Sbjct: 428 SEA---SSSPTTAEDTSIATSTPSEGSTPL----TSMPVSTTPVASSEASNLSTTPVDSK 480

Query: 784 SSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITD-SVKRFPKEEATEGNATSPPQNPPT 842
           +  T  T+    P     +      P      +T  SV   P   +     ++ P +  T
Sbjct: 481 TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTST 540

Query: 843 NLT 845
            +T
Sbjct: 541 PVT 543



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 66/262 (25%), Positives = 97/262 (37%), Gaps = 17/262 (6%)

Query: 238  TVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNE-TTVKLPA 296
            T+P   P   I  T         T      S    P+   I V +I  G    TT+ +P+
Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS 3943

Query: 297  S-LMFEISDALK-TQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSAL 354
            + +    +D    T  A +  +    E  TP     S+  TT +  T    T P  ++A 
Sbjct: 3944 TPVTSSTADVFPATTGAVSTPVITSTELNTPST---SSSSTTTSFSTTKEFTTPAMTTAA 4000

Query: 355  DVSETTLASSEKPWIVP----TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTAT 410
             ++  T++++           T   S  S    P T+T  V + P T    E S   T T
Sbjct: 4001 PLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTST-SVTTRPVTPSS-ESSRPSTIT 4058

Query: 411  SDRILDSIPPKTSRTLEQPRATLAPSET--PFVPQKLEIFTSPEMQPTTPAPQQTTSIPS 468
            S  I  + PP  S T   P  T A S T  P     +   T P  + T+     TT++P+
Sbjct: 4059 SHTIPPTFPPAHSST---PPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPT 4115

Query: 469  TPKRRPRPKPPRTKPERTTSAG 490
                +  P    T P  TT  G
Sbjct: 4116 NTTIKSNPTSTPTVPRTTTCFG 4137



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 76/319 (23%), Positives = 116/319 (36%), Gaps = 32/319 (10%)

Query: 231  STYDQDHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLI---IPGL 287
            ST   D + P     K    +I  +V    T + S  S    PL  +++   +    PG 
Sbjct: 3836 STPPGDTSTPLLTSTKAGSFSIPAEV---TTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892

Query: 288  N-ETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRST 346
            +  +T  L  S  F  S    T  A   T+ +   + T  V  I+   T  T   +P + 
Sbjct: 3893 SIASTPPLDTSTTFTPS----TDTASTPTIPV---ATTISVSVITEGSTPGTTIFIPST- 3944

Query: 347  KPTTSSALDVSETTLASSEKPWIVPTA--KISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404
             P TSS  DV   T  +   P I  T     S  S       +T   F++P  +    ++
Sbjct: 3945 -PVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003

Query: 405  DSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIF-TSPEMQPTTPAPQQT 463
                +T+     S P  TSR      +TL+ + TP     +     +P  + + P+   +
Sbjct: 4004 YVTMSTAP----STPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITS 4059

Query: 464  TSIPSTPKRRPRPKPPRTKPERTT-SAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIP 522
             +IP T        PP T    TT +   +T   +++   T TT  P  T          
Sbjct: 4060 HTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVT--------TT 4111

Query: 523  LSPEVTHTKPAPKQTPRAP 541
              P  T  K  P  TP  P
Sbjct: 4112 AVPTNTTIKSNPTSTPTVP 4130


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 84.0 bits (206), Expect = 7e-16
 Identities = 146/646 (22%), Positives = 234/646 (36%), Gaps = 103/646 (15%)

Query: 243   VPRKLIPITIIKQVIQNVTHKDSAKS-PEKAPLGGVILVHLIIPGLNETTVKLPASLMFE 301
             +P + +P+ + K+        +  K  PEK  L  V     + P    T ++   S+ F 
Sbjct: 10299 IPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVL--VPKKEAVPPAKGRTVLEEKVSVAFR 10356

Query: 302   ----ISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVS 357
                 + + L+ ++ + E   +P E +  EVE+                         +V 
Sbjct: 10357 QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEE-----------------GEFHEVE 10399

Query: 358   ETTLASSEKPWIVPTAKISEDSKVLQP-QTATYDVFSSPTTSDE-PEISDSYTATSDRIL 415
             E      E+  +    ++ +  +V++  +    +VF  P    + PEIS+          
Sbjct: 10400 E--FIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI-------- 10449

Query: 416   DSIPPKTSRTLEQPRATLAPSETPFVPQKL---EIFTSPEMQ--PTTPAPQQTTSIPSTP 470
               IPPK   T   PR    P++ P VP+K+   E    PE    P T  P+        P
Sbjct: 10450 --IPPKKPPTKVVPRKE-PPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP 10506

Query: 471   KRRPRPKPPRTKPERTTSAGTITPKISKSPE---PTWTTPAPGKTQFISLKPKIPLS--P 525
             +++  P PP  KPE         PK+ ++P+   P    P P        KP++P +  P
Sbjct: 10507 EKKV-PVPPAKKPEAPP------PKVPEAPKEVVPEKKVPVPPPK-----KPEVPPTKVP 10554

Query: 526   EVTHTKPAPKQTPRA-PPKPKTSPRPRIPQTQ----PVPKVPQRVTAKPKTSP------- 573
             EV       K+ P A PPKP+ SP P +P+      P  KVP     KP+ +P       
Sbjct: 10555 EVPKAAVPEKKVPEAIPPKPE-SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP 10613

Query: 574   ---SPEVSYTTPAPKDVLLPHKPYPEVSQ-SEPAPLETRGIPFIPMISPSPS--QEELQT 627
                 PE     P PK   +P    PEV + + P       IP  P  SP P   +E  + 
Sbjct: 10614 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPE-SPPPEVFEEPEEV 10672

Query: 628   TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGA 687
              LEE      E      P    +      P +    V  +  + P ++  V + P+    
Sbjct: 10673 ALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVK--VPEVPKEVVP 10730

Query: 688   DRNVSVDSTHPTKKPGTRRPPLP------PRPTHPRRKPLPPNNVTGKPGSAGIISSGPI 741
             ++ V +      + P  + P +P       +   P++  +PP  V   P    +     +
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV 10790

Query: 742   TTPPLRSTPRPTG-------TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLG 794
               P    +P P          P E I  + ++P   A  EE E        P    +P  
Sbjct: 10791 PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE-----VPPPAVPEEP-- 10843

Query: 795   KPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNP 840
             K       V  I+KP+  P    +  K   K +        PP  P
Sbjct: 10844 KKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPP 10889



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 113/536 (21%), Positives = 195/536 (36%), Gaps = 71/536 (13%)

Query: 318   LPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISE 377
             +P E K    EKI    T    E V             V         +  + P  ++ E
Sbjct: 9839  VPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE 9898

Query: 378   DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSE 437
               K L+P+   ++         E  ++       +   + I  +     E+    + P +
Sbjct: 9899  VPKELEPEEVAFE---------EEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVK 9949

Query: 438   TPFVPQKLEIFTSPEMQPTTPAPQQTTS----IPSTPKRRPRPKPPRTKPERTTSAGTIT 493
              P VP+K      PE +   P P++  +    +P  PK+ P  K P   P++        
Sbjct: 9950  VPEVPRK----PVPEEKKPVPVPKKKEAPPAKVPEVPKK-PEEKVPVLIPKKEKPPPAKV 10004

Query: 494   PKISKSPEPTWTTPAPGKTQFISLKPKIPLSPE--VTHTK---PAPKQTPRAPPKPKTSP 548
             P++ K P P    P P   +  +   K+P  P+  V   K   PAPK+    P K    P
Sbjct: 10005 PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVP 10064

Query: 549   RPRIPQTQPVPKVPQRVTAKP-----KTSPSPEVSYTTPAPKDVLLPHKPYPE----VSQ 599
             +  IP+ +    VP++V A P     K  P P V    P  ++VL   +  PE      +
Sbjct: 10065 KKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP-VPVALPQEEEVLFEEEIVPEEEVLPEE 10123

Query: 600   SEPAPLETRGIPFIPMISPSPSQ---EELQTTLEETDQSTQEPFTTKIPRTTELAKTTQA 656
              E  P E   +P    + P   +   EE +   EE     +E F  +     E+      
Sbjct: 10124 EEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPV 10183

Query: 657   PHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHP 716
             P      ++ + ++K  + P  ++AP               P K P   +     R   P
Sbjct: 10184 PAP-VPEIKKKVTEKKVVIPKKEEAP---------------PAKVPEVPKKVEEKRIILP 10227

Query: 717   RRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEEL 776
             + + + P  VT +P         PI+   +   P      +E +E ++  P VP   E +
Sbjct: 10228 KEEEVLPVEVTEEP------EEEPISEEEIPEEP----PSIEEVE-EVAPPRVP---EVI 10273

Query: 777   ENITDFSSSPT--RETDPLGKPRFKGPHVRY---IQKPDNSPCSITDSVKRFPKEE 827
             +     + +P   +   P  K   K P  +    +QK +  P  + +  K+ P+++
Sbjct: 10274 KKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKK 10329



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 136/649 (20%), Positives = 218/649 (33%), Gaps = 120/649 (18%)

Query: 234   DQDHTVPAYVPRKLIPITII--KQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETT 291
             ++    P  VP  L P  ++  K+V      K  A  P+       ++    +P      
Sbjct: 10486 EEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKK 10545

Query: 292   VKLPASLMFEISDALKTQLAKNETLALPAESKTPEV----------EKISARPTTVTPET 341
              ++P + + E+  A   +    E +    ES  PEV          +K+ A P    PE 
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK-KPEV 10604

Query: 342   VPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEP 401
              P          +   +  +   +KP + PT K+ E  KV  P+    +       S  P
Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT-KVPEVPKVAVPEKKVPEAIPPKPESPPP 10663

Query: 402   EISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQ 461
             E+ +      + +    PP  +  +E+P     P  T  VP K  +            P+
Sbjct: 10664 EVFEE----PEEVALEEPP--AEVVEEPEPAAPPQVT--VPPKKPVPEKKAPAVVAKKPE 10715

Query: 462   -QTTSIPSTPKRR-PRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLK- 518
                  +P  PK   P  K P   P++  +     P++ K   P      P K +    K 
Sbjct: 10716 LPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV 10775

Query: 519   PKIPLSPEVTHTKPA---PKQTPRAPPKPKTSPRPRIPQTQ------------------- 556
             P++P  P V   KPA   P++    PP+    P    P+ +                   
Sbjct: 10776 PEVPKKP-VLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEV 10834

Query: 557   PVPKVPQ---------------RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSE 601
             P P VP+               +  A P   P PE     P  K    P  P P     +
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVK 10894

Query: 602   PAPLETRGIP---------------FIPMISPSPSQEELQTTLEETDQSTQEPFTTK--I 644
                 + + IP                 P+  P   +++++  L E     +E    K  +
Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPG-GEKKVRKLLPERKPEPKEEVVLKSVL 10953

Query: 645   PRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGT 704
              +  E  +    P +     +P   + P  +P V++   P+   R   +    PTK P  
Sbjct: 10954 RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKP-VEEVEVPTVTKRERKI--PEPTKVPEI 11010

Query: 705   RRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDI 764
             +  P  P P  P  KP P   V              I  PP+   P P   P+       
Sbjct: 11011 K--PAIPLPA-PEPKPKPEAEVK------------TIKPPPVEPEPTPIAAPV------- 11048

Query: 765   KQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813
                TVP  G++ E     + +P  E     KP  KGP ++ + K   SP
Sbjct: 11049 ---TVPVVGKKAE-----AKAPKEEA---AKP--KGP-IKGVPKKTPSP 11083



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 71/343 (20%), Positives = 128/343 (37%), Gaps = 46/343 (13%)

Query: 334  PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFS 393
            P  V  +  P   K      ++  E T    E+  +  T K+ E SK + PQ  +     
Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVT-KVPEVSKKIVPQKPS----R 9220

Query: 394  SPTTSDEPEISDSYTATSDRILDSIPPK-TSRTLEQPRATLAPSETPFVPQ-KLEIFTSP 451
            +P   +  E+      T   ++        S T E+   T+   +   V + K+ +  S 
Sbjct: 9221 TPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISK 9280

Query: 452  EMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGK 511
             ++P    P+    +P  P   P    P   P++        P++ K P P    P P  
Sbjct: 9281 RVEPPPKVPE----LPEKPA--PEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVP 9334

Query: 512  TQFISLKPKIPLSPEVTHTKPAPKQTPRAP-PKPKTSPRPRIPQTQ-------------- 556
             +  +  PK+P  P+    KP P++    P  K K +P  ++P+ Q              
Sbjct: 9335 KKEPAAPPKVPEVPK----KPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390

Query: 557  -------PVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609
                    VP++P++   + +     +     P PK   LP KP PE   + P P+  + 
Sbjct: 9391 REESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKA 9450

Query: 610  IPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAK 652
                    P  ++   +T +EE     +E  +  +P+  E+ +
Sbjct: 9451 -------PPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTR 9486



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 160/768 (20%), Positives = 259/768 (33%), Gaps = 127/768 (16%)

Query: 243   VPRKLIPITIIKQVIQNVTHKDSAKSPE--KAPLGGVILVHLIIPGLNETTVKLPASLMF 300
             VP + +P+ + K+V         AK PE  K P+              E  V +PA    
Sbjct: 10012 VPEEKVPVPVPKKV-----EAPPAKVPEVPKKPVP-------------EKKVPVPAPKKV 10053

Query: 301   EISDALKTQLAKNETLALPAESK-TPEVEKISARPTTV--------TPETVPRSTKPTTS 351
             E   A   ++ K     +P E K TP  +K+ A P  V         P  +P+  +    
Sbjct: 10054 EAPPAKVPEVPKK---LIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110

Query: 352   SALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATS 411
               +   E  L   E+        + E+ +VL  +             +E    +      
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170

Query: 412   DRILDSIPPK--------------TSRTLEQPRATLAP-SETPFVPQKLEIFTSPEMQPT 456
             + +L  + PK              T + +  P+   AP ++ P VP+K+E     E +  
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVE-----EKRII 10225

Query: 457   TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTI-------TPKISKSPEPTWTTPAP 509
              P  ++   +  T +    P      PE   S   +        P++ K   P   TP P
Sbjct: 10226 LPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVP 10285

Query: 510   GKTQFISLKPKIPLSPEVTHTK-PAPKQTPRAPPK-----PKTSPRPRI--PQTQPVPKV 561
              K +     P   +S ++   K P P Q   APP      PK  P  ++  P+ + VP  
Sbjct: 10286 KKVE----APPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPA 10341

Query: 562   PQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEV--SQSEPAPLETRGIPFIPMISPS 619
               R   + K S    V++     ++V++  +   EV  ++ E  P E             
Sbjct: 10342 KGRTVLEEKVS----VAFR----QEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEG 10393

Query: 620   PSQEELQTTLEETDQSTQEPFTTKIPRTTEL---------------AKTTQAPHRFYTTV 664
                E  +    E  +  +E    K+ R  E+                K  +   +     
Sbjct: 10394 EFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPK 10453

Query: 665   RPRTSDKPHIRPGVK--QAPRPSGADRNVSVDS---THPTKKPGTRRPPLPPRPTHPRRK 719
             +P T   P   P  K  + P+    +  V V       PTK P      LPP+   P +K
Sbjct: 10454 KPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV----LPPKEVVPEKK 10509

Query: 720   -PLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASG----E 774
              P+PP      P     +   P    P +  P P   P +      K P VP +     +
Sbjct: 10510 VPVPPAKKPEAPPPK--VPEAPKEVVPEKKVPVP--PPKKPEVPPTKVPEVPKAAVPEKK 10565

Query: 775   ELENITDFSSSPTRETDPLGK---PRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEG 831
               E I     SP  E     K   P  K P     +KP+ +P  + ++ K    E+    
Sbjct: 10566 VPEAIPPKPESPPPEVPEAPKEVVPEKKVP-AAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624

Query: 832   NATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMT 891
                  P+ PPT +  V     P   + +   P  ++    EV          + + + + 
Sbjct: 10625 PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPP-EVFE--------EPEEVALE 10675

Query: 892   NQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSE 939
                   VE  +P    +  V PK P+ E      VA   E    +V E
Sbjct: 10676 EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPE 10723



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 83/351 (23%), Positives = 131/351 (37%), Gaps = 39/351 (11%)

Query: 536   QTPRAPPK----------PKTSPRPRIPQTQP---VPKVPQRVTAKPKTSPSPEVSYTTP 582
             + P+APPK          PK  P   +P+ +P   VP+VP+++  + K     E      
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPT 10493

Query: 583   APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTT 642
                +VL P +  PE     P   +    P  P +  +P +   +  +        E   T
Sbjct: 10494 KVPEVLPPKEVVPEKKVPVPPAKKPEAPP--PKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10551

Query: 643   KIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV-----DSTH 697
             K+P   E+ K      +    + P+    P   P V +AP+    ++ V           
Sbjct: 10552 KVP---EVPKAAVPEKKVPEAIPPKPESPP---PEVPEAPKEVVPEKKVPAAPPKKPEVT 10605

Query: 698   PTKKPGTRRPPLPPR--PTHPRRKP-LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTG 754
             P K P   +  +P +  P  P +KP +PP  V   P  A      P   PP   +P P  
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665

Query: 755   TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKP--RFKGPHVRYIQKPDNS 812
                E  E  +++P      EE E      ++P + T P  KP    K P V   +KP+  
Sbjct: 10666 FE-EPEEVALEEPPAEVV-EEPE-----PAAPPQVTVPPKKPVPEKKAPAV-VAKKPELP 10717

Query: 813   PCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKP 863
             P  + +  K    E+         P+ PP  +  V  E  P   +   +KP
Sbjct: 10718 PVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKP 10768



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 123/629 (19%), Positives = 222/629 (35%), Gaps = 93/629 (14%)

Query: 318  LPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSE-----------TTLASSEK 366
            +P    TPE +K   +   VT + V +  K   +   +++            TTL  ++ 
Sbjct: 8965 IPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKA 9024

Query: 367  PWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTL 426
            P I+  +  +E+ K++             T + + E+     A  +        K     
Sbjct: 9025 PEIIDVSSKAEEVKIM-------------TITRKKEVQKEKEAVYE--------KKQAVH 9063

Query: 427  EQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERT 486
            ++ R  +   E P+   ++E +T P  QP    P +         +    K    + E  
Sbjct: 9064 KEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAK----KEVHEEWEED 9119

Query: 487  TSAGTITPKISKS---PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTP--RAP 541
               G    +  +     E  W   A  + + I ++ ++    E +H +  P + P  +AP
Sbjct: 9120 FEEGQEYYEREEGYDEGEEEWEE-AYQEREVIQVQKEVY---EESHERKVPAKVPEKKAP 9175

Query: 542  PKPKTSPRPRIPQTQPVPKVPQRVTA-KPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS 600
            P PK   +P I   + + K  +R+   K + +  PEVS         ++P KP     Q 
Sbjct: 9176 PPPKVIKKPVI---EKIEKTSRRMEEEKVQVTKVPEVSKK-------IVPQKPSRTPVQE 9225

Query: 601  EPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRF 660
            E   ++   +    M+    S+E++          T+E  +  +P   E+ K      + 
Sbjct: 9226 EVIEVKVPAVHTKKMVI---SEEKMFFA-----SHTEEEVSVTVP---EVQKEIVTEEKI 9274

Query: 661  YTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKP 720
            +  +  R    P + P + + P P   +    V      + P  + P +P +P    +KP
Sbjct: 9275 HVAISKRVEPPPKV-PELPEKPAP---EEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKP 9330

Query: 721  LP-PNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVP---ASGEEL 776
            +P P      P     +   P+   P    P P     E      K P V     + E++
Sbjct: 9331 VPVPKKEPAAPPKVPEVPKKPV---PEEKIPVPVAKKKEA--PPAKVPEVQKGVVTEEKI 9385

Query: 777  ENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATE------ 830
              +T    SP      +  P+ K P  R               V   PK+   E      
Sbjct: 9386 TIVTQREESPPPAVPEI--PKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVP 9443

Query: 831  ---GNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNK- 886
                    PP+   +  TVV  +   +   L +  P    VT +EV + E  S+S + + 
Sbjct: 9444 VPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEG 9503

Query: 887  -SIQMTNQTFSTVENLKPNTSYEFQVKPK 914
             SI +  +     E     T YE   +P+
Sbjct: 9504 VSISVYREEEREEEEEAEVTEYEVMEEPE 9532



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 74/332 (22%), Positives = 111/332 (33%), Gaps = 58/332 (17%)

Query: 446   EIFTSPEMQ-PTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTW 504
             E  T PE   P  P P++   +P+ PK  P                    K+ K   P  
Sbjct: 9784  EYITEPEKPIPVKPVPEEP--VPTKPKAPPA-------------------KVLKKAVPEE 9822

Query: 505   TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564
               P P   +     PK+P  P+    +       +   +  T P  ++P        P+R
Sbjct: 9823  KVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK------PKR 9876

Query: 565   VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF----IPMISPSP 620
             V A+ K           P P+  + P    PEV    P  LE   + F    +  +    
Sbjct: 9877  VVAEEK----------VPVPRKEVAPPVRVPEV----PKELEPEEVAFEEEVVTHVEEYL 9922

Query: 621   SQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHR-FYTTVRPRTSDKPHIRPGVK 679
              +EE +   EE +  T+E     IP      K  + P +      +P    K    P  K
Sbjct: 9923  VEEEEEYIHEEEEFITEEEVVPVIP-----VKVPEVPRKPVPEEKKPVPVPKKKEAPPAK 9977

Query: 680   QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLP-PNNVTGKPGSAGIISS 738
                 P   +  V V      K P  + P +P +P    + P+P P  V   P     +  
Sbjct: 9978  VPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPK 10037

Query: 739   GPITTPPLRSTPRPTGTPLERIETDIKQPTVP 770
              P+   P +  P P    +E      K P VP
Sbjct: 10038 KPV---PEKKVPVPAPKKVE--APPAKVPEVP 10064



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 25/161 (15%)

Query: 824   PKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGS 880
             P    T  N   PP NPP  L V       S V L W +P +D    VT Y +  +E  +
Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVT-----KSSVSLSWSRPKDDGGSRVTGYYIERKETST 30373

Query: 881   FSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLG---EGPVSNTVAFS---TESAD 934
                   +      T  TV  L P+  Y+F++  +N +G     P S  V       + + 
Sbjct: 30374 DKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQ 30433

Query: 935   PRVSEPVSAGRDAI---WTERPFNSDSYSECKGKQYVKRTW 972
             P   E +S  +D++   W E+P       EC G + +   W
Sbjct: 30434 PGELEILSISKDSVTLQW-EKP-------ECDGGKEILGYW 30466



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 14/132 (10%)

Query: 814   CSITDSVKRFPKEEATEGNATS-------PPQNPPTNLTVVTVEGCPSFVILDWEKPLND 866
             C   D+ K   K E + G+ ++           PP NL V  V    +F++  WE P+ D
Sbjct: 24085 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WEPPIID 24142

Query: 867   ---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVS 923
                 V  Y +  RE+   +  N S + +  +F  VENL     Y F+V  +N  G G   
Sbjct: 24143 GGAKVKNYVIDKRESTRKAYANVSSKCSKTSFK-VENLTEGAIYYFRVMAENEFGVGVPV 24201

Query: 924   NTVAFSTESADP 935
              TV  + ++A+P
Sbjct: 24202 ETVD-AVKAAEP 24212



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 35/104 (33%), Positives = 47/104 (45%), Gaps = 14/104 (13%)

Query: 841   PTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFST 897
             P NLT+  V+     V L WE PL D    +T Y V  RE    +    +   T  TF  
Sbjct: 25202 PVNLTIREVK--KDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFR- 25258

Query: 898   VENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADP-RVSEP 940
             +ENL+   SY F+V   N  G       +    E+ +P +VSEP
Sbjct: 25259 IENLQEGCSYYFRVLASNEYG-------IGLPAETTEPVKVSEP 25295



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 6/118 (5%)

Query: 837   PQNPPTNLTVVT-VEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTN 892
             P  PPT+   +T  E   S + LDW++P ++    +  Y +  R +     +  + ++  
Sbjct: 15291 PLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCP 15350

Query: 893   QTFSTVENLKPNTSYEFQVKPKNPLGEGPVS--NTVAFSTESADPRVSEPVSAGRDAI 948
              T   VENL  +  YEF+VK  N +GE   S    V    +   P +   +S   D I
Sbjct: 15351 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 15408



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 34/89 (38%), Positives = 40/89 (44%), Gaps = 8/89 (8%)

Query: 833   ATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQ 889
             AT  P  PP  L VV      S  +L W KP +D    +T Y +  R+ GS         
Sbjct: 28542 ATEQPA-PPRRLDVVDTS--KSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAG-- 28596

Query: 890   MTNQTFSTVENLKPNTSYEFQVKPKNPLG 918
              T Q   TVE L   T YEF+VK KN  G
Sbjct: 28597 HTKQLTFTVERLVEKTEYEFRVKAKNDAG 28625



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 115/633 (18%), Positives = 210/633 (33%), Gaps = 101/633 (15%)

Query: 217  KTVVGSKKVNGKIQSTYDQDHTVPAY----VPRKLIPITIIKQV------IQNVTHKDSA 266
            K +V  +K++  I    +    VP       P ++ P+ I K+V      +  V  K   
Sbjct: 9266 KEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVP 9325

Query: 267  KS------PEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPA 320
            +       P+K P     +  +    + E  + +P +   E   A   ++ K     +  
Sbjct: 9326 EEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKG----VVT 9381

Query: 321  ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSK 380
            E K   V +    P    PE +P+   P     +   E  +    K   +P   + E+  
Sbjct: 9382 EEKITIVTQREESPPPAVPE-IPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKV 9440

Query: 381  VLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPF 440
             +    A          S +  + +      +++  ++P +   T  +     A  E  +
Sbjct: 9441 AVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHE---VSAEEEWSY 9497

Query: 441  VPQK----LEIFTSPEMQPTTPAPQQTTSIPSTPK------------RRPRPKPPRTKPE 484
              ++    + ++   E +    A      +   P+            +R   +P     E
Sbjct: 9498 SEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVT-E 9556

Query: 485  RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIP--LSPEVTHTKPAPKQTPRAPP 542
            R      + PKI    E     P P K       P+ P  + PE     P PK+    PP
Sbjct: 9557 RQEKKIVLKPKIPAKIEE----PPPAKV------PEAPKKIVPEKKVPAPVPKKEKVPPP 9606

Query: 543  KPKTSPRPRIPQTQPVPKV-------PQRVT--------------------AKPKTSPSP 575
            K    P+  +P+ +  PKV       P +VT                    A PK     
Sbjct: 9607 KVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPE 9666

Query: 576  EVSYTTPAPKDVLLPHK----PYPEVSQSEPAPLETRGIPF-IPMISPSPSQEELQTTLE 630
            E     P  K + L  K    P  +V++     ++   +    P   P P +E   T +E
Sbjct: 9667 EPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKE--VTIME 9724

Query: 631  ETDQS-TQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADR 689
            E +++ T E     + R  E  +  +  ++ +    P      +     ++  R    + 
Sbjct: 9725 EKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEE 9784

Query: 690  NVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTP-PLRS 748
             +    T P K    +  P  P PT P+    PP  V  K      +    +  P P + 
Sbjct: 9785 YI----TEPEKPIPVKPVPEEPVPTKPK---APPAKVLKK-----AVPEEKVPVPIPKKL 9832

Query: 749  TPRPTGTPLERIETDIKQPTVPASGEELENITD 781
             P P   P E  +   ++  +  +  E E +T+
Sbjct: 9833 KPPPPKVPEEPKKVFEEKIRISITKREKEQVTE 9865



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 29/161 (18%)

Query: 535 KQTPRAPPKPKT-SPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP 593
           K  PR PPKPK+ SP P        P +  +     + SPSP             + H P
Sbjct: 252 KTPPRIPPKPKSRSPTP--------PSIAAKAQLARQQSPSP-------------IRHSP 290

Query: 594 YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP----RTTE 649
            P      P P   R +     IS SP +      L    Q++      ++P    +   
Sbjct: 291 SPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGY 350

Query: 650 LAKTTQAPHR---FYTTVRPRTSDKPHIRPGVKQAPRPSGA 687
           +A +++A  R     T+ + RT ++   R GV++    SGA
Sbjct: 351 VASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGA 391



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 8/108 (7%)

Query: 840   PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896
             PP N+T+  V      V L WE P  D    +T Y +  R+  S               +
Sbjct: 13193 PPLNVTITDVNRFG--VSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSA 13250

Query: 897   TVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADP--RVSEPVS 942
             TV ++     Y F+V+ +N +G G  S    F  + ADP  R S PV+
Sbjct: 13251 TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPF-VKVADPIERPSPPVN 13297



 Score = 38.1 bits (87), Expect = 0.045
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 15/118 (12%)

Query: 840   PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTN---Q 893
             PPTN+TV  V       +L W+ P ND    V  Y +  RE    + K   + +TN   +
Sbjct: 26280 PPTNITVQDVT--KESAVLSWDVPENDGGAPVKNYHIEKRE----ASKKAWVSVTNNCNR 26333

Query: 894   TFSTVENLKPNTSYEFQVKPKNPLGEGPVSNT---VAFSTESADPRVSEPVSAGRDAI 948
                 V NL+    Y F+V  +N  G G  + T   V  + + + P      S  +D++
Sbjct: 26334 LSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSV 26391



 Score = 37.4 bits (85), Expect = 0.077
 Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 14/161 (8%)

Query: 824   PKEEATEGNATSP--PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISREN 878
             P E      A  P  P +PP  L +  +    + V L W+ P ND    VT Y V     
Sbjct: 15996 PVETIQRTTARDPIYPPDPPIKLKIGLIT--KNTVHLSWKPPKNDGGSPVTHYIVECLAW 16053

Query: 879   GSFSGKNKSIQMTN-----QTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESA 933
                  K ++ +  N     +   TVE+L     YEF+VK  N  G    S TV    +  
Sbjct: 16054 DPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVG-PCDCQ 16112

Query: 934   DPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYK 974
              P +   +   ++ +  E   N +  ++ KG  +   TW+K
Sbjct: 16113 RPDMPPSIDL-KEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 16152



 Score = 37.4 bits (85), Expect = 0.077
 Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 6/88 (6%)

Query: 837   PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQ 893
             P  PP  + +   +   S + L W KP+ D    VT Y V  R+         S +   +
Sbjct: 27166 PPGPPAKIRIA--DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223

Query: 894   TFS-TVENLKPNTSYEFQVKPKNPLGEG 920
             T    V NLKP  +Y F+V   N  G+G
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQG 27251



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 13/103 (12%)

Query: 824   PKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGS 880
             P + AT  +  +PP  P   +T  T     S   L+W  PL D    VT Y V  +E G 
Sbjct: 16409 PSDPATARDPIAPPGPPFPKVTDWT----KSSADLEWSPPLKDGGSKVTGYIVEYKEEGK 16464

Query: 881   FS---GKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG 920
                  GK+K ++ T      V  LK    Y+F+V+  N  G G
Sbjct: 16465 EEWEKGKDKEVRGTKLV---VTGLKEGAFYKFRVRAVNIAGIG 16504



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 9/112 (8%)

Query: 856   VILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVK 912
             +++ W +P+N+    V  Y +  +E  S      +  + + T    +NL+    YEF+V 
Sbjct: 23439 MVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVY 23498

Query: 913   PKNPLGEGPVS-NTVAFSTESA--DPRVSEPVSAGRDAI---WTERPFNSDS 958
              +N +G G  S N+  +        P   EP+   R+ I   WT+  ++  S
Sbjct: 23499 AENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGS 23550



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 17/108 (15%)

Query: 835   SPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMT 891
             SPP  P        V+   + + + W KPL D    +T Y V  +++     K  SIQ  
Sbjct: 26085 SPPSKPKI------VDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKT-SIQSL 26137

Query: 892   NQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSE 939
               T  T+  L     Y F+VK  N +G    S       +S+DP++++
Sbjct: 26138 RGTEYTISGLTTGAEYVFRVKSVNKVGASDPS-------DSSDPQIAK 26178



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 7/100 (7%)

Query: 844   LTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVEN 900
             +T VT + C    ++ W+ P +D    +  Y +  RE       + + +   +T  +V+N
Sbjct: 30833 ITAVTKDSC----VVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKN 30888

Query: 901   LKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP 940
             L     YEF+VK +N  GE   S      T  +D  +  P
Sbjct: 30889 LIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAP 30928



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 824   PKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGS 880
             P +    G+   PP  PP+   V   +   S + L W+ P  D    +  Y V  +E G+
Sbjct: 15692 PSDPEVAGDPIFPP-GPPSCPEVK--DKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGT 15748

Query: 881   FSGK--NKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNT 925
                K  N+  ++       V NLK    Y F+VK  N  GE   S+T
Sbjct: 15749 TDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT 15795



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 13/94 (13%)

Query: 837   PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRE-------NGSFSGKNK 886
             P  PPTN  VV  +     + L W KP+ D    +  Y V  R        +  +   N 
Sbjct: 18496 PPGPPTNFRVV--DTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNA 18553

Query: 887   SIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG 920
             + Q+  + F TV +L  N  YEF+V  +N +G G
Sbjct: 18554 AAQLVRKEF-TVTSLDENQEYEFRVCAQNQVGIG 18586



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 7/91 (7%)

Query: 836   PPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTF 895
             P QN    +T VT E C     + WE PL++  +E      E    + K  SI  ++ T 
Sbjct: 18004 PCQN--LKVTNVTKENCT----ISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTK 18057

Query: 896   STVE-NLKPNTSYEFQVKPKNPLGEGPVSNT 925
               ++ NL  N  Y F+V  +N +G GP   T
Sbjct: 18058 RLIKANLLANNEYYFRVCAENKVGVGPTIET 18088



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 5/90 (5%)

Query: 837   PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQ 893
             P  PP    V  V    +   + W++P++D    +T Y V  RE  S           + 
Sbjct: 20571 PPGPPEKPEVSNVT--KNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSD 20628

Query: 894   TFSTVENLKPNTSYEFQVKPKNPLGEGPVS 923
                 V  L+  ++YEF+V  +N  G GP S
Sbjct: 20629 LRCKVTGLQEGSTYEFRVSAENRAGIGPPS 20658



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 46/203 (22%), Positives = 73/203 (35%), Gaps = 22/203 (10%)

Query: 856   VILDWEKPLNDTVTE---YEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVK 912
             V L WEKP  D   E   Y V  R++G  + K  + +       T+  L   T YEF+V 
Sbjct: 30447 VTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVF 30506

Query: 913   PKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTW 972
              +N  G      T            +  +      + T+    +    +  G+      W
Sbjct: 30507 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 30566

Query: 973   YKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLTSDQ 1032
             Y+   G +L  S +YK+    S  G+ + +       ED   +         G+  TS +
Sbjct: 30567 YR--FGKELIQSRKYKM----SSDGRTHTLTVMTEEQEDEGVYT-CIATNEVGEVETSSK 30619

Query: 1033  L------------PIKEGYFRAV 1043
             L            P+KE Y+ AV
Sbjct: 30620 LLLQATPQFHPGYPLKEKYYGAV 30642



 Score = 34.3 bits (77), Expect = 0.65
 Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 14/169 (8%)

Query: 840   PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896
             PP N+TV  +    ++V   WE P+ D    +  Y V  R+    S    + + +  +F 
Sbjct: 19789 PPVNVTVKEISKDSAYVT--WEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFR 19846

Query: 897   TVENLKPNTSYEFQVKPKNPLGEGPVSNT--VAFSTESADPRVS---EPVSAGRDAIWTE 951
              V NL+   SY F+V  +N  G G    T     ++++  P V      VS    +I  +
Sbjct: 19847 -VANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWK 19905

Query: 952   RPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFY 1000
             +P +SD  S   G      T   K+  V    SL+Y     D   GK Y
Sbjct: 19906 KP-HSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYS--AKDLTEGKEY 19951



 Score = 33.9 bits (76), Expect = 0.85
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 840   PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896
             PPT   +   E    FV   W+ P ND    ++ Y V  R+  S +    +  +   T+ 
Sbjct: 21161 PPTG-PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 21219

Query: 897   TVENLKPNTSYEFQVKPKNPLGEGP 921
                 L     Y+F+VK +N  G GP
Sbjct: 21220 ATR-LTTGLEYQFRVKAQNRYGVGP 21243



 Score = 33.9 bits (76), Expect = 0.85
 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 14/97 (14%)

Query: 485   RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKP 544
             R T     +P   KSPEP   +P   K+      PK   SPE +H K        +P + 
Sbjct: 32654 RVTEKAVTSPPRVKSPEPRVKSPEAVKS------PKRVKSPEPSHPKAV------SPTET 32701

Query: 545   KTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTT 581
             K +P  ++ Q  PV   P ++T   K   S E++  T
Sbjct: 32702 KPTPTEKV-QHLPV-SAPPKITQFLKAEASKEIAKLT 32736



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 840   PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896
             PP N+ +  +    + V L W++P  D    +T Y V  R+         S     +T  
Sbjct: 26770 PPRNVRITDIS--KNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQF 26827

Query: 897   TVENLKPNTSYEFQVKPKNPLG 918
              +  L  N+ YEF+V  +N +G
Sbjct: 26828 IISGLTQNSQYEFRVFARNAVG 26849



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 837   PQNPPTNLTVVTV-EGCPSFVILDWEKPLNDTVTEY-----EVISRENGSFSGKNKSIQM 890
             P NPP   TVV V +   + V L+W KP+ D   E      E+   + G +   N    +
Sbjct: 28250 PVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV 28309

Query: 891   TNQTFSTVENLKPNTSYEFQVKPKNPLGEG 920
               +T  TV +L+    Y+F+V   N  G+G
Sbjct: 28310 --KTRYTVTDLQAGEEYKFRVSAINGAGKG 28337



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 16/89 (17%)

Query: 839   NPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTF 895
             +PP NL V  ++    +  L W+ PL++    +T Y +  R+        K  +    T 
Sbjct: 15499 SPPRNLAVTDIKAESCY--LTWDAPLDNGGSEITHYVIDKRD-----ASRKKAEWEEVTN 15551

Query: 896   STVEN------LKPNTSYEFQVKPKNPLG 918
             + VE       L PN  YEF+V+  N  G
Sbjct: 15552 TAVEKRYGIWKLIPNGQYEFRVRAVNKYG 15580



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 33/101 (32%), Positives = 43/101 (42%), Gaps = 15/101 (14%)

Query: 824   PKEEATEGNATSPPQNP-PTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRE-- 877
             P E     +   PP  P P N+T  TV        L W KP       +T Y V  R+  
Sbjct: 21347 PSEPMLALDPIDPPGKPVPLNITRHTVT-------LKWAKPEYTGGFKITSYIVEKRDLP 21399

Query: 878   NGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLG 918
             NG +   N S  + N+   TV  L  + +YEF+V  KN  G
Sbjct: 21400 NGRWLKANFSNILENEF--TVSGLTEDAAYEFRVIAKNAAG 21438



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 39/124 (31%), Positives = 49/124 (39%), Gaps = 12/124 (9%)

Query: 479  PRTKPERTTSAGTITPKIS---KSPE-PTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAP 534
            PR +   T      T +I    K P+ P    P P  T  I   P   + P V    P P
Sbjct: 8911 PRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIP--TMPIRAVPPEEIPPVVA--PPIP 8966

Query: 535  KQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKP 593
               P   P+ K  P  RI  T+  V K  ++V AKPK     E     P P   L+P K 
Sbjct: 8967 LLLPT--PEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKA 9024

Query: 594  YPEV 597
             PE+
Sbjct: 9025 -PEI 9027



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 22/105 (20%)

Query: 100   LIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPN 159
             ++ V P  PP+             P +L     T S++ L W     P  +   P     
Sbjct: 15286 ILAVDPLGPPTS------------PERLTYTERTKSTITLDWK---EPRSNGGSPI---- 15326

Query: 160   DRFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFGVK 202
              + Y I  R  DK   ++   ++CP T  +VENL  + +YEF VK
Sbjct: 15327 -QGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVK 15370



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 860   WEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 916
             W +P+ D    ++ Y +  R+  S        +    T   V  L  N+ Y+++V   N 
Sbjct: 27086 WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNA 27145

Query: 917   LGEGPVSNTVAFSTESADP 935
              G+GP S    F  ++ADP
Sbjct: 27146 AGQGPFSEPSEF-YKAADP 27163



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 10/116 (8%)

Query: 839   NPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTF 895
             +PP NLT  + +   S V L WE PL D    +  Y +   E G  +    ++++  +  
Sbjct: 13293 SPPVNLT--SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELT 13350

Query: 896   STVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEP---VSAGRDAI 948
               V  L+    Y ++V  +N  G    S  +   T  AD    EP   +SA +D +
Sbjct: 13351 YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLT--ADDAFVEPTMDLSAFKDGL 13404



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%)

Query: 847   VTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKP 903
             +T E C     L W  P +D    +T Y +  RE+   +    +  +T Q  +TV+ L  
Sbjct: 16628 LTNESCK----LTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQ 16682

Query: 904   NTSYEFQVKPKNPLGEGPVSNT 925
               +Y F++  +N +G GP   T
Sbjct: 16683 GKAYFFRIAAENSIGMGPFVET 16704



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 833   ATSPPQNP--PTNLTVVTVEGCPSFVILDWEKPLNDTVT---EYEVISRENGSFSGKNKS 887
             A +P   P  P NL +   +   +FV L W +P  D  +    Y V  R  GS   +   
Sbjct: 18094 AINPIDRPGEPENLHIA--DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH 18151

Query: 888   IQMTNQTFSTVENLKPNTSYEFQVKPKNPLGE 919
                  +T   V+    N  YEF+V+ KN  GE
Sbjct: 18152 KGSIKETHYMVDRCVENQIYEFRVQTKNEGGE 18183



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 31/118 (26%), Positives = 48/118 (40%), Gaps = 15/118 (12%)

Query: 837   PQNPPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQ 893
             P +PP     + V+   + + L W KP+ D    +T Y V  R+         S     +
Sbjct: 23520 PCDPPGTPEPIMVKR--NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIE 23577

Query: 894   TFSTVENLKPNTSYEFQVKPKNPLG--------EGPVS--NTVAFSTESADPRVSEPV 941
             T  TV  L  +  YEF+V  KN  G         GP++  + V     S DP+  + +
Sbjct: 23578 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTI 23635



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)

Query: 540   APPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSP---SPEVSYTTPAPKDVLLPHKPYPE 596
             +PP+ K SP PR+   + V K P+RV +   + P   SP  +  TP  K   LP    P+
Sbjct: 32662 SPPRVK-SPEPRVKSPEAV-KSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPK 32719

Query: 597   VSQ 599
             ++Q
Sbjct: 32720 ITQ 32722



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 858   LDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPK 914
             + W  P ND    VT Y V  RE    +    + ++   +F  V NL P   Y F+V   
Sbjct: 18717 VSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH-VTNLVPGNEYYFRVTAV 18775

Query: 915   NPLGEGPVSNTVAFSTESADPRVSEP 940
             N  G G V   V     ++DP +SEP
Sbjct: 18776 NEYGPG-VPTDVPKPVLASDP-LSEP 18799



 Score = 30.8 bits (68), Expect = 7.2
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 840   PPTNLTVVTVEGCPSFVILDWEKPLND---TVTEYEVISRENGSFSGKNKSIQMTNQTFS 896
             PP +L V  +     +  L W++PL+D    +T Y V  R+  S      S     ++  
Sbjct: 17312 PPRDLEVSEIRKDSCY--LTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF 17369

Query: 897   TVENLKPNTSYEFQVKPKNPLGEGPVSNT 925
               ++L     Y F+V  +N  G GP   T
Sbjct: 17370 A-KHLNEGNQYLFRVAAENQYGRGPFVET 17397



 Score = 30.8 bits (68), Expect = 7.2
 Identities = 15/37 (40%), Positives = 21/37 (56%)

Query: 105   PAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSW 141
             P+PP + +K+C    +   P    V  +T SSVFLSW
Sbjct: 22822 PSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 22858



 Score = 30.8 bits (68), Expect = 7.2
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 10/105 (9%)

Query: 829   TEGNATSPPQNPPT-NLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKS 887
             T  N   PP  P T  ++ +T +     +++ W +P++D  TE E    E     G   +
Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDS----MVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 24949

Query: 888   IQMTNQTFST----VENLKPNTSYEFQVKPKNPLGEGPVSNTVAF 928
              +   +T +     V  L    SYEF+V  +N  G G  S    F
Sbjct: 24950 -KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVF 24993


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 42/274 (15%)

Query: 403 ISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP----TTP 458
           ++ +  AT+     + P  +++    P  T  P     +  +  + TS  +       +P
Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSP 160

Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTT------SAGTITPKISKSPE--------PTW 504
           APQ TT+ P TP       P  + P  TT      SA T  P  S +P         P  
Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220

Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564
           TTPAP         P     PE T   P P  T    P P +S  P  P+T  VP  P  
Sbjct: 221 TTPAP---------PSSSAPPETTAAPPTPSAT---TPAPLSSSAP--PETTAVPPTPSA 266

Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624
            T  P ++ +P  +   P       P  P      S PAP ET      P+ +P+ S   
Sbjct: 267 TTLDPSSASAPPETTAAPPTPSATTPAPP------SSPAPQETTA---APITTPNSSPTT 317

Query: 625 LQTTLEETDQSTQEPFTTKI-PRTTELAKTTQAP 657
           L     ET  +     TT +  +TT   + T AP
Sbjct: 318 LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 93/329 (28%), Positives = 125/329 (37%), Gaps = 50/329 (15%)

Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459
           +P I  SY     R    +PP  +   + P     P + P  P K     +P +  TT  
Sbjct: 56  KPFIRKSYKCLHKRCRPKLPPSPNNPPKFPN----PHQPPKHPDKNSSVVNPTLVATTQI 111

Query: 460 PQQT-----TSIPSTPKRRPRPKPPRTKPER-----TTSAGTITPKISKSPEPTWTTPAP 509
           P  T     T I + P     P+   T   R     ++S  T+ P  S +P+ T   P P
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP-P 170

Query: 510 GKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569
             +      P     PE T   P P  T +APP   +S  P  P+T   P  P   T  P
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPP---SSSAP--PETTAAPPTPPATTPAP 225

Query: 570 KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629
            +S +P    TT AP          P  S + PAPL +   P    + P+PS     TTL
Sbjct: 226 PSSSAP--PETTAAP----------PTPSATTPAPLSSSAPPETTAVPPTPS----ATTL 269

Query: 630 EETDQSTQEPFTTKIP----RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685
           + +  S   P TT  P     TT    ++ AP    TT  P T+  P+  P    AP  S
Sbjct: 270 DPSSASA-PPETTAAPPTPSATTPAPPSSPAPQE--TTAAPITT--PNSSP-TTLAPDTS 323

Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRPT 714
                 S   TH T    T +     +PT
Sbjct: 324 ----ETSAAPTHQTTTSVTTQTTTTKQPT 348



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 30/283 (10%)

Query: 518 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV-----PQRVTAKPKTS 572
           +PK+P SP      P P Q P+ P K  +   P +  T  +P V       ++T  P  +
Sbjct: 71  RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130

Query: 573 PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEET 632
             P+ + T  + ++V            + PAP +T   P      P+PS      T    
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP------PTPS-----ATTPAP 179

Query: 633 DQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692
             S+  P TT  P T   + TTQAP    ++  P T+  P   P    AP  S A    +
Sbjct: 180 PSSSAPPETTAAPPTP--SATTQAPPS--SSAPPETTAAPPTPPATTPAPPSSSAPPETT 235

Query: 693 V-----DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR 747
                  +T P     +  P     P  P    L P++ +  P +     +   TTP   
Sbjct: 236 AAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295

Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 790
           S+P P  T    I T    PT  A      + ++ S++PT +T
Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLA-----PDTSETSAAPTHQT 333



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 62/209 (29%), Positives = 84/209 (40%), Gaps = 20/209 (9%)

Query: 311 AKNETLALPA--ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368
           A  +T A P    + TP     SA P T      P +T     S+    ETT A    P 
Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220

Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
             P    +  S    P+T       S TT   P  S +   T+     ++PP  S T   
Sbjct: 221 TTP----APPSSSAPPETTAAPPTPSATT-PAPLSSSAPPETT-----AVPPTPSATTLD 270

Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTT 487
           P +  AP ET   P      T     P++PAPQ+TT+ P +TP   P    P T    T+
Sbjct: 271 PSSASAPPETTAAPPTPSATT--PAPPSSPAPQETTAAPITTPNSSPTTLAPDT--SETS 326

Query: 488 SAGTITPKISKSPEPTWT---TPAPGKTQ 513
           +A T     S + + T T   T APG+ +
Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 42/274 (15%)

Query: 403 ISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP----TTP 458
           ++ +  AT+     + P  +++    P  T  P     +  +  + TS  +       +P
Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSP 160

Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTT------SAGTITPKISKSPE--------PTW 504
           APQ TT+ P TP       P  + P  TT      SA T  P  S +P         P  
Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220

Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564
           TTPAP         P     PE T   P P  T    P P +S  P  P+T  VP  P  
Sbjct: 221 TTPAP---------PSSSAPPETTAAPPTPSAT---TPAPLSSSAP--PETTAVPPTPSA 266

Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624
            T  P ++ +P  +   P       P  P      S PAP ET      P+ +P+ S   
Sbjct: 267 TTLDPSSASAPPETTAAPPTPSATTPAPP------SSPAPQETTA---APITTPNSSPTT 317

Query: 625 LQTTLEETDQSTQEPFTTKI-PRTTELAKTTQAP 657
           L     ET  +     TT +  +TT   + T AP
Sbjct: 318 LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 93/329 (28%), Positives = 125/329 (37%), Gaps = 50/329 (15%)

Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459
           +P I  SY     R    +PP  +   + P     P + P  P K     +P +  TT  
Sbjct: 56  KPFIRKSYKCLHKRCRPKLPPSPNNPPKFPN----PHQPPKHPDKNSSVVNPTLVATTQI 111

Query: 460 PQQT-----TSIPSTPKRRPRPKPPRTKPER-----TTSAGTITPKISKSPEPTWTTPAP 509
           P  T     T I + P     P+   T   R     ++S  T+ P  S +P+ T   P P
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP-P 170

Query: 510 GKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569
             +      P     PE T   P P  T +APP   +S  P  P+T   P  P   T  P
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPP---SSSAP--PETTAAPPTPPATTPAP 225

Query: 570 KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629
            +S +P    TT AP          P  S + PAPL +   P    + P+PS     TTL
Sbjct: 226 PSSSAP--PETTAAP----------PTPSATTPAPLSSSAPPETTAVPPTPS----ATTL 269

Query: 630 EETDQSTQEPFTTKIP----RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685
           + +  S   P TT  P     TT    ++ AP    TT  P T+  P+  P    AP  S
Sbjct: 270 DPSSASA-PPETTAAPPTPSATTPAPPSSPAPQE--TTAAPITT--PNSSP-TTLAPDTS 323

Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRPT 714
                 S   TH T    T +     +PT
Sbjct: 324 ----ETSAAPTHQTTTSVTTQTTTTKQPT 348



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 30/283 (10%)

Query: 518 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV-----PQRVTAKPKTS 572
           +PK+P SP      P P Q P+ P K  +   P +  T  +P V       ++T  P  +
Sbjct: 71  RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130

Query: 573 PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEET 632
             P+ + T  + ++V            + PAP +T   P      P+PS      T    
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP------PTPS-----ATTPAP 179

Query: 633 DQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692
             S+  P TT  P T   + TTQAP    ++  P T+  P   P    AP  S A    +
Sbjct: 180 PSSSAPPETTAAPPTP--SATTQAPPS--SSAPPETTAAPPTPPATTPAPPSSSAPPETT 235

Query: 693 V-----DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR 747
                  +T P     +  P     P  P    L P++ +  P +     +   TTP   
Sbjct: 236 AAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295

Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 790
           S+P P  T    I T    PT  A      + ++ S++PT +T
Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLA-----PDTSETSAAPTHQT 333



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 62/209 (29%), Positives = 84/209 (40%), Gaps = 20/209 (9%)

Query: 311 AKNETLALPA--ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368
           A  +T A P    + TP     SA P T      P +T     S+    ETT A    P 
Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220

Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
             P    +  S    P+T       S TT   P  S +   T+     ++PP  S T   
Sbjct: 221 TTP----APPSSSAPPETTAAPPTPSATT-PAPLSSSAPPETT-----AVPPTPSATTLD 270

Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTT 487
           P +  AP ET   P      T     P++PAPQ+TT+ P +TP   P    P T    T+
Sbjct: 271 PSSASAPPETTAAPPTPSATT--PAPPSSPAPQETTAAPITTPNSSPTTLAPDT--SETS 326

Query: 488 SAGTITPKISKSPEPTWT---TPAPGKTQ 513
           +A T     S + + T T   T APG+ +
Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 42/274 (15%)

Query: 403 ISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQP----TTP 458
           ++ +  AT+     + P  +++    P  T  P     +  +  + TS  +       +P
Sbjct: 101 VNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSP 160

Query: 459 APQQTTSIPSTPKRRPRPKPPRTKPERTT------SAGTITPKISKSPE--------PTW 504
           APQ TT+ P TP       P  + P  TT      SA T  P  S +P         P  
Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220

Query: 505 TTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 564
           TTPAP         P     PE T   P P  T    P P +S  P  P+T  VP  P  
Sbjct: 221 TTPAP---------PSSSAPPETTAAPPTPSAT---TPAPLSSSAP--PETTAVPPTPSA 266

Query: 565 VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624
            T  P ++ +P  +   P       P  P      S PAP ET      P+ +P+ S   
Sbjct: 267 TTLDPSSASAPPETTAAPPTPSATTPAPP------SSPAPQETTA---APITTPNSSPTT 317

Query: 625 LQTTLEETDQSTQEPFTTKI-PRTTELAKTTQAP 657
           L     ET  +     TT +  +TT   + T AP
Sbjct: 318 LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 93/329 (28%), Positives = 125/329 (37%), Gaps = 50/329 (15%)

Query: 400 EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPA 459
           +P I  SY     R    +PP  +   + P     P + P  P K     +P +  TT  
Sbjct: 56  KPFIRKSYKCLHKRCRPKLPPSPNNPPKFPN----PHQPPKHPDKNSSVVNPTLVATTQI 111

Query: 460 PQQT-----TSIPSTPKRRPRPKPPRTKPER-----TTSAGTITPKISKSPEPTWTTPAP 509
           P  T     T I + P     P+   T   R     ++S  T+ P  S +P+ T   P P
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP-P 170

Query: 510 GKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569
             +      P     PE T   P P  T +APP   +S  P  P+T   P  P   T  P
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAPP---SSSAP--PETTAAPPTPPATTPAP 225

Query: 570 KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL 629
            +S +P    TT AP          P  S + PAPL +   P    + P+PS     TTL
Sbjct: 226 PSSSAP--PETTAAP----------PTPSATTPAPLSSSAPPETTAVPPTPS----ATTL 269

Query: 630 EETDQSTQEPFTTKIP----RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685
           + +  S   P TT  P     TT    ++ AP    TT  P T+  P+  P    AP  S
Sbjct: 270 DPSSASA-PPETTAAPPTPSATTPAPPSSPAPQE--TTAAPITT--PNSSP-TTLAPDTS 323

Query: 686 GADRNVSVDSTHPTKKPGTRRPPLPPRPT 714
                 S   TH T    T +     +PT
Sbjct: 324 ----ETSAAPTHQTTTSVTTQTTTTKQPT 348



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 72/283 (25%), Positives = 109/283 (38%), Gaps = 30/283 (10%)

Query: 518 KPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKV-----PQRVTAKPKTS 572
           +PK+P SP      P P Q P+ P K  +   P +  T  +P V       ++T  P  +
Sbjct: 71  RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130

Query: 573 PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEET 632
             P+ + T  + ++V            + PAP +T   P      P+PS      T    
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP------PTPS-----ATTPAP 179

Query: 633 DQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS 692
             S+  P TT  P T   + TTQAP    ++  P T+  P   P    AP  S A    +
Sbjct: 180 PSSSAPPETTAAPPTP--SATTQAPPS--SSAPPETTAAPPTPPATTPAPPSSSAPPETT 235

Query: 693 V-----DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLR 747
                  +T P     +  P     P  P    L P++ +  P +     +   TTP   
Sbjct: 236 AAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295

Query: 748 STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 790
           S+P P  T    I T    PT  A      + ++ S++PT +T
Sbjct: 296 SSPAPQETTAAPITTPNSSPTTLA-----PDTSETSAAPTHQT 333



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 62/209 (29%), Positives = 84/209 (40%), Gaps = 20/209 (9%)

Query: 311 AKNETLALPA--ESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368
           A  +T A P    + TP     SA P T      P +T     S+    ETT A    P 
Sbjct: 161 APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPA 220

Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
             P    +  S    P+T       S TT   P  S +   T+     ++PP  S T   
Sbjct: 221 TTP----APPSSSAPPETTAAPPTPSATT-PAPLSSSAPPETT-----AVPPTPSATTLD 270

Query: 429 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP-STPKRRPRPKPPRTKPERTT 487
           P +  AP ET   P      T     P++PAPQ+TT+ P +TP   P    P T    T+
Sbjct: 271 PSSASAPPETTAAPPTPSATT--PAPPSSPAPQETTAAPITTPNSSPTTLAPDT--SETS 326

Query: 488 SAGTITPKISKSPEPTWT---TPAPGKTQ 513
           +A T     S + + T T   T APG+ +
Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 149/674 (22%), Positives = 228/674 (33%), Gaps = 75/674 (11%)

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
           P     P + K     T  + + +P  +  T S     S T L    K  ++P      +
Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG--FLSE 159

Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438
              L   ++  + F+      + E S   T    +++     K    ++ P     P   
Sbjct: 160 VNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP- 218

Query: 439 PFVPQKLEIFTSPEMQPTTP---APQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK 495
             +P++      P  Q  TP   + QQ   I S P    +P    T+  +T  A     +
Sbjct: 219 --IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276

Query: 496 ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTP-RAPPKPKTSPRPRIPQ 554
            +  P+        G+    S+KP +P   +    +P P + P + P   K+ P P  P 
Sbjct: 277 DASRPQTKQADIVRGE----SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332

Query: 555 TQPV----PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGI 610
            QP     P   Q  T KP   P      TT  P   L P KP  + + SE    E  G 
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPG----TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 611 PFI---PMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPR 667
             +   P +  +P+Q+              +P T ++     LA   Q P        P 
Sbjct: 389 KALAQPPGVGKTPAQQP----------GPAKPPTQQVGTPKPLA---QQPGLQSPAKAPG 435

Query: 668 TSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 727
            +  P  +PG  + P         S   T PTK P     P  P P  P     PP    
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ--- 492

Query: 728 GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPT-VPASGE-ELENITDFSSS 785
            +PGSA   S  P +T P    P P   P  +     K P+  P S +   +  +    S
Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGP-AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550

Query: 786 PTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLT 845
             + T P+ +     P    +Q P  SP +     +  PK      N T    + P    
Sbjct: 551 AQQSTKPVSQTGSGKP----LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 846 VVTVEGCPSFVILDWEKPLNDTVTEYEV---------------ISRENGSFSGKNKSIQM 890
             T   C + V        N  +TE +                ++    S   K K+  +
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666

Query: 891 TNQTFSTVENLKP---NTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDA 947
           T  T S V    P    TS +    PK  L + P         +   P V +P   G  +
Sbjct: 667 T--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP-------EPKKPPPLVKQPTLHGSPS 717

Query: 948 IWTERPFNSDSYSE 961
              ++P  +DS S+
Sbjct: 718 AKAKQPPEADSLSK 731



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 102/422 (24%), Positives = 159/422 (37%), Gaps = 79/422 (18%)

Query: 419  PPKTSRTLEQPRATLAPSETPFVPQKLEIFT--SPEMQPTTPAPQQTTSIPSTPKRRPRP 476
            P K    ++QP    +PS     P + +  +  +P  +P+ P+ Q    +     ++P+ 
Sbjct: 700  PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759

Query: 477  KPPRTKPERTTSAGT---ITPKISKSPEPTWTTPAPGKTQFISLKPKIP-----LSPEVT 528
              P T    ++SA T   I     +S     TTP P KT         P     +SP  +
Sbjct: 760  VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PLKTDSAKPSQSFPPTGEKVSPFDS 818

Query: 529  HTKPAPKQTPRAPPKPKTSPRPR-IPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDV 587
               P P    +    P  S   +   Q  PV K  +   A+ K SP P+     P PK  
Sbjct: 819  KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK---PMPKGS 875

Query: 588  LLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL---EETDQSTQEPFTTKI 644
              P  P P   Q+ P P +          SP P ++  + +L     TD    +P T + 
Sbjct: 876  PTPPGPRPTAGQTVPTPQQ----------SPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925

Query: 645  PRTTEL-----AKTTQAPHRFYTTVRPRTSDKPHIRPG----VKQAPRPS------GADR 689
              T +L     +  +QA +   T  +P     PH + G    +KQAP PS      G  +
Sbjct: 926  TVTGKLFGFGASIFSQASNLISTAGQP----GPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 690  NV---------SVDSTHPTKKPGTRR--PPLPPRPTHPR----RKPLP---PNNVTGKPG 731
            +          S+     TK P   +  P     PT  R    +KP P     ++T +P 
Sbjct: 982  STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041

Query: 732  SAGIISSGPITTPPLRSTPRPTGT-PLERIETDI--KQP----TVPASGEELENITDFSS 784
             A       +    L  +P+P  T PL + E +I  K P    T      ++ N+  F+ 
Sbjct: 1042 KA-------VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094

Query: 785  SP 786
            +P
Sbjct: 1095 TP 1096



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 83/375 (22%), Positives = 131/375 (34%), Gaps = 62/375 (16%)

Query: 314  ETLALPAESKTPEVEKISAR-PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPT 372
            ++L+ PA  K P V     + P        P+  KPTT      S TT     KP I P+
Sbjct: 727  DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT-----KPDI-PS 780

Query: 373  AKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRAT 432
            +K+         Q+   +  + P  +D  + S S+  T +++     P  S+ + +P + 
Sbjct: 781  SKV---------QSQAEEKTTPPLKTDSAKPSQSFPPTGEKV----SPFDSKAIPRPASD 827

Query: 433  --LAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490
              +     P    K +    P  +   P   QT   P  P  +P PK   T P    +AG
Sbjct: 828  SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPTAG 886

Query: 491  TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT---- 546
               P   +SP+P               +     S  +     APK  P  P +  T    
Sbjct: 887  QTVPTPQQSPKPQ--------------EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932

Query: 547  -------SPRPRIPQT--QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEV 597
                   S    +  T  QP P       A  K +P+P    T+  P             
Sbjct: 933  GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP---------KST 983

Query: 598  SQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAP 657
             Q+ PAP   + IP +   + +P+ E+L+   E+     +     K P   +    T  P
Sbjct: 984  GQAPPAP--AKSIP-VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040

Query: 658  HRFYTTVRPRTSDKP 672
             +     +   S KP
Sbjct: 1041 QKAVLPTKLEKSPKP 1055



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 123/559 (22%), Positives = 188/559 (33%), Gaps = 77/559 (13%)

Query: 319 PAESKTPEVEKISARPTTVTPETV---PRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375
           P  +K P  +  SA+P +  P +    P+   P   S      T   S +     P+A+ 
Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543

Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAP 435
              +K    Q +T  V  S T S +P    + + ++ +      PKT   L      L  
Sbjct: 544 PSPAKP-SAQQSTKPV--SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL- 599

Query: 436 SETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP-------ERTTS 488
                VP+K    T  E Q         T++ S     P P     K         +   
Sbjct: 600 ----HVPEKANFNTCTECQ---------TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646

Query: 489 AGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP 548
            G + P +  SP+P   T AP  T           +  V+ + P P+QT    PK   +P
Sbjct: 647 GGDLAP-VPSSPQPKLKT-APVTT-----------TSAVSKSSPQPQQTS---PKKDAAP 690

Query: 549 RPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL---LPHKPYPEVSQSEPAPL 605
           +  + +  P PK P  +  +P    SP      P   D L    P K     S+ + AP+
Sbjct: 691 KQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749

Query: 606 ETRGIPFIPMISP-----SPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ----- 655
                    M+ P     S S    +  +  +   +Q    T  P  T+ AK +Q     
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809

Query: 656 ----APHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPP 711
               +P       RP +  K    PG   +    G  +   V      KK  T+  P P 
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPG--PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867

Query: 712 RPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI-ETDIKQPTVP 770
               P+  P PP    G   +AG     P  +P  +   R     L  I +    QPT P
Sbjct: 868 AKPMPKGSPTPP----GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923

Query: 771 ---ASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEE 827
               +G+         S  +      G+P   GPH    Q    +P     +  + P  +
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQP---GPH---SQSGPGAPMKQAPAPSQPPTSQ 977

Query: 828 ATEGNATSPPQNPPTNLTV 846
               +    P  P  ++ V
Sbjct: 978 GPPKSTGQAPPAPAKSIPV 996



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 89/403 (22%), Positives = 135/403 (33%), Gaps = 52/403 (12%)

Query: 327  VEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQT 386
            V  +S   +++    VP+   P      D   T L  SEK  +    K + +  +L+   
Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVA----DTVSTDLLISEKDPVKKAKKETGNGIILEVLE 2318

Query: 387  ATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPK---------TSRTLEQPR-ATLAPS 436
            A  D         +  +S++        + ++P K         +  T  Q + A+  PS
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378

Query: 437  ETPFV---PQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT 493
             +P V   P K   F        +  P      P  P   P P PP   P  T+   TI 
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL 2438

Query: 494  PKISKSPEPTWTTPAPG-------KTQFISLKPKIPLSPEVTHTKPAPKQTPRA------ 540
            PK   +     TT  P        +T  +     +P++   T   P     P +      
Sbjct: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498

Query: 541  ------PPKPKTSPRPRIPQTQPVPKVPQRVTAKPK----TSPS-----PEVSYTTPAPK 585
                  P KP  +P+P IPQ     + P  +  KP     TS           Y  P+P 
Sbjct: 2499 FTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPT 2558

Query: 586  DVLLPH--KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT----LEETDQSTQEP 639
              L PH  K  P  S+S         +P  P      S  +  T+        D  + EP
Sbjct: 2559 SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618

Query: 640  FTTKIPRTTELAKTTQAPHRFYTTVRPRT-SDKPHIRPGVKQA 681
              + +P  T +     +   FY +   +T S  P   P   QA
Sbjct: 2619 VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 75/330 (22%), Positives = 111/330 (33%), Gaps = 56/330 (16%)

Query: 292  VKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTS 351
            VK    L+   S   K  +  ++  +   E  TP ++  SA+P+   P T  +   P  S
Sbjct: 760  VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-VSPFDS 818

Query: 352  SALD--VSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTA 409
             A+    S++ + S   P      +   D    + +        SP    +P    S T 
Sbjct: 819  KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878

Query: 410  TSDRILDSIPPKTSRTLEQPRATLAPSETP--FVPQKLEIFTSPEMQPTTPAPQQTTSI- 466
               R      P   +T+  P+ +  P E    F      I  +P+ QPTTP    T  + 
Sbjct: 879  PGPR------PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932

Query: 467  ---------------------------PSTP-KRRPRPKPPRTKPERTTSAGTITPKISK 498
                                       P  P K+ P P  P T      S G   P  +K
Sbjct: 933  GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 499  SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPV 558
            S      T AP   +   L+PK   +P V  T     +T + PP  K S        + +
Sbjct: 993  SIPVKKETKAPAAEK---LEPKAEQAPTVKRT-----ETEKKPPPIKDS--------KSL 1036

Query: 559  PKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588
               PQ+     K   SP+   T P  K  L
Sbjct: 1037 TAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 144/636 (22%), Positives = 236/636 (37%), Gaps = 107/636 (16%)

Query: 268  SPEKAPLGGVILVHLIIPGLNETTV---KLP-ASLMFEI-SDALKTQLAKNETLALP--- 319
            SP +AP+G           + E+T+   ++P ASL   + S A  T    + TL++P   
Sbjct: 2081 SPTQAPIG---------EDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVK 2131

Query: 320  --AESKTPEVE-KISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWI---VPTA 373
                  T E+E +     T    E +   +   T S    S T++  S+ P +   V + 
Sbjct: 2132 ITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSV 2191

Query: 374  KISEDSKVLQPQTATYDVFSSPTT-----SDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
              ++ S  +    +   V++ P        D  EIS S T     I+D  P + S +L++
Sbjct: 2192 CTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSS-TYFPGSIID-YPEEISVSLDR 2249

Query: 429  PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488
                   +    +   L    S  ++   P P+   +   +       K P  K ++ T 
Sbjct: 2250 TAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETG 2309

Query: 489  AGTITPKIS-----KSPEPTWTTPAPGKTQFI---SLKPKIPLSPEVTHTKPAPKQTPRA 540
             G I   +      K  E   T  +  +T F    S    +P+  +++ T     +T   
Sbjct: 2310 NGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET--- 2366

Query: 541  PPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT---SPSPEVSYTTPAPKDVLLPHKPYPE 596
                +  P  ++P   P V  +P    AKP+    S S ++S   P P     P  P P 
Sbjct: 2367 --FGQEKPASQLPSGSPSVSSLP----AKPRPFFRSSSLDISAQPPPPPP---PPPPPPP 2417

Query: 597  VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP---RTTELAKT 653
                 P P      P  P  SP P      T L +   +   P TT  P     T L  T
Sbjct: 2418 PPPPPPPP------PLPPPTSPKP------TILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 654  TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRP 713
                       R  T+  P + P  K +  PSG      +  TH   +P   +PP+ P+P
Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPP--KPSSIPSG------LVFTH---RPEPSKPPIAPKP 2514

Query: 714  THPR--RKPLPPNNVTGKPGSAGIISSG------------PITTPPL-----RSTPRPTG 754
              P+       P ++  KP    + SS             P  T PL     +S+PR + 
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574

Query: 755  TPLER--IETDIKQPTVPASGEELENITDFS-SSPTRETDPLGKPRFKGPHVRYIQKPDN 811
            +  E   + T   +P  P      + IT +   SP+++   +       P V  ++ P +
Sbjct: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634

Query: 812  SPCS--ITDSVKRFPKEEATEGNATSPPQNPPTNLT 845
            S  +  I+ +++ F    AT   A S  Q  PT++T
Sbjct: 2635 SEQTFYISGALQTF---SATPVTAPSSFQAAPTSVT 2667



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 130/646 (20%), Positives = 213/646 (32%), Gaps = 96/646 (14%)

Query: 312  KNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVP 371
            K +   +P  S TP   + +A  T  TP+  P+  + +   +L++   T A   +P    
Sbjct: 865  KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP---T 921

Query: 372  TAKISEDSKVLQPQTATYDVFS---SPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
            T + +   K+     + +   S   S      P       A   +      P TS+   +
Sbjct: 922  TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 429  PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488
                  P+    +P K E   +P  +   P  +Q  ++  T   +   KPP  K  ++ +
Sbjct: 982  STGQAPPAPAKSIPVKKET-KAPAAEKLEPKAEQAPTVKRTETEK---KPPPIKDSKSLT 1037

Query: 489  A----GTITPKISKSPEPTWTTPAPGKTQFISLK--PKIPLSPEVTHT-------KPAPK 535
            A      +  K+ KSP+P  T P       I  K  P      E  +         P P 
Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097

Query: 536  QT--------------------------PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569
             T                          P AP  PK SP P      P     Q+    P
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP-----VPTESSSQKTAVPP 1152

Query: 570  --KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQ- 626
              K     E    T A K +L   +   E    E  P         PM++    QEE + 
Sbjct: 1153 QVKLVKKQEQEVKTEAEKVIL---EKVKETLSMEKIP---------PMVTTDQKQEESKL 1200

Query: 627  -----TTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQA 681
                 + L+E     +E     IP   ++    + P       +P   DK  +      A
Sbjct: 1201 EKDKASALQEKKPLPEE--KKLIPEEEKIRSEEKKP--LLEEKKPTPEDKKLLPEAKTSA 1256

Query: 682  PRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRK--PLPPNNVTGKPGSAGIISSG 739
            P     D   S       K  G   P        P+ K   LP    +G P S  +    
Sbjct: 1257 PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP----SGTPQS--LPKED 1310

Query: 740  PITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFK 799
              TT  ++  P+P  T     + D  +P    + +E +     SS   +    L    + 
Sbjct: 1311 DKTTKTIKEQPQPPCT----AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366

Query: 800  GPHVRYI--QKPDNSPCSITDSVKRFPKEE-ATEGNATSPPQNPPTNLTVVTVEGCPSFV 856
               +     + P   P    D +K   K+  + E + +SP        TV+++    +  
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426

Query: 857  ILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLK 902
            + D EK  ++  T+   +S E      K +S+  T +   + E +K
Sbjct: 1427 LAD-EK--SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK 1469



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 33/321 (10%)

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPT-----AKISE--DSKVLQPQTATYDVFSSPTT 397
            S +  T  ++D S  T    +  W +PT     A++ +  DS     +T      SS   
Sbjct: 3459 SRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAV 3518

Query: 398  SDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
                EIS            SI  +    +E  +   AP +T +    L   T  +    +
Sbjct: 3519 QTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKT-YKGGSLGCQTEADSDTQS 3577

Query: 458  PAPQQTTSIPSTPKRRPRPKPPR---TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQF 514
            P   Q  S  S PK + RP P     +   R  S   + P   KSP+  ++  +P     
Sbjct: 3578 P---QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP----- 3629

Query: 515  ISLKPKIPL-SPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT- 571
              L P   L S  V + KP P     +P K       ++P   P   K+ QR  + PK  
Sbjct: 3630 --LSPGKALESAFVPYEKPLPDDI--SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685

Query: 572  SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631
            SP+ + S   P         K    ++ S       R +P       +P  EE+ T  + 
Sbjct: 3686 SPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLP-------NPPPEEISTGTQS 3738

Query: 632  TDQSTQEPFTTKIPRTTELAK 652
            T  +       +I RT  +A+
Sbjct: 3739 TFSTMGTVSRRRICRTNTMAR 3759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 25/152 (16%)

Query: 411  SDRILDSIPP---KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP 467
            SD  + S  P   ++   +E+PR       + F+P + +   S  + PT+P  Q   S P
Sbjct: 3835 SDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQT-ESQLVPPTSPYTQYQYSSP 3893

Query: 468  STPKRRP-----------------RPKPPRTKPE-RTTSAGTITPKISKSPEPTWTTPAP 509
            + P + P                 +  P +T+P  +  +  + TP++  +P P  +   P
Sbjct: 3894 ALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLP 3953

Query: 510  GKTQFISLKPK---IPLSPEVTHTKPAPKQTP 538
             +   I  KP+   + L P++T      +  P
Sbjct: 3954 SQMMVIQQKPRQTTLYLEPKITSNYEVIRNQP 3985



 Score = 34.3 bits (77), Expect = 0.65
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 9/82 (10%)

Query: 639 PFTTKIPRTTE--LAKTTQAPHRFYTTVRPRTSDKPH--IRPGVKQAPRPSGADRNVSVD 694
           P  T IP   E  L++ ++   R    V  R    P   + P   ++P      R   +D
Sbjct: 32  PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESP---SMHRKQELD 88

Query: 695 STHPTKKPGTRRPPLPPRPTHP 716
           S+HP K+ G  RPP P RP  P
Sbjct: 89  SSHPPKQSG--RPPDPGRPAQP 108



 Score = 34.3 bits (77), Expect = 0.65
 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 526  EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA-P 584
            EV+ T+P   ++     +P+T+P+    Q  P P+        P TSP  +  Y++PA P
Sbjct: 3838 EVSSTRPTRIESQHGIERPRTAPQTEFSQFIP-PQTQTESQLVPPTSPYTQYQYSSPALP 3896

Query: 585  KDVLLPHKP----------YPEVS--QSEPAPLETRGIPFIPMISPSPSQE 623
                  +            + +VS  Q++P       + F P + P+P+ +
Sbjct: 3897 TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ 3947


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 149/674 (22%), Positives = 228/674 (33%), Gaps = 75/674 (11%)

Query: 319 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED 378
           P     P + K     T  + + +P  +  T S     S T L    K  ++P      +
Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG--FLSE 159

Query: 379 SKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSET 438
              L   ++  + F+      + E S   T    +++     K    ++ P     P   
Sbjct: 160 VNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP- 218

Query: 439 PFVPQKLEIFTSPEMQPTTP---APQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK 495
             +P++      P  Q  TP   + QQ   I S P    +P    T+  +T  A     +
Sbjct: 219 --IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276

Query: 496 ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTP-RAPPKPKTSPRPRIPQ 554
            +  P+        G+    S+KP +P   +    +P P + P + P   K+ P P  P 
Sbjct: 277 DASRPQTKQADIVRGE----SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332

Query: 555 TQPV----PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGI 610
            QP     P   Q  T KP   P      TT  P   L P KP  + + SE    E  G 
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPG----TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 611 PFI---PMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPR 667
             +   P +  +P+Q+              +P T ++     LA   Q P        P 
Sbjct: 389 KALAQPPGVGKTPAQQP----------GPAKPPTQQVGTPKPLA---QQPGLQSPAKAPG 435

Query: 668 TSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 727
            +  P  +PG  + P         S   T PTK P     P  P P  P     PP    
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ--- 492

Query: 728 GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPT-VPASGE-ELENITDFSSS 785
            +PGSA   S  P +T P    P P   P  +     K P+  P S +   +  +    S
Sbjct: 493 -QPGSAKPPSQQPGSTKPPPQQPGP-AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550

Query: 786 PTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLT 845
             + T P+ +     P    +Q P  SP +     +  PK      N T    + P    
Sbjct: 551 AQQSTKPVSQTGSGKP----LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 846 VVTVEGCPSFVILDWEKPLNDTVTEYEV---------------ISRENGSFSGKNKSIQM 890
             T   C + V        N  +TE +                ++    S   K K+  +
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666

Query: 891 TNQTFSTVENLKP---NTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDA 947
           T  T S V    P    TS +    PK  L + P         +   P V +P   G  +
Sbjct: 667 T--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP-------EPKKPPPLVKQPTLHGSPS 717

Query: 948 IWTERPFNSDSYSE 961
              ++P  +DS S+
Sbjct: 718 AKAKQPPEADSLSK 731



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 102/422 (24%), Positives = 159/422 (37%), Gaps = 79/422 (18%)

Query: 419  PPKTSRTLEQPRATLAPSETPFVPQKLEIFT--SPEMQPTTPAPQQTTSIPSTPKRRPRP 476
            P K    ++QP    +PS     P + +  +  +P  +P+ P+ Q    +     ++P+ 
Sbjct: 700  PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759

Query: 477  KPPRTKPERTTSAGT---ITPKISKSPEPTWTTPAPGKTQFISLKPKIP-----LSPEVT 528
              P T    ++SA T   I     +S     TTP P KT         P     +SP  +
Sbjct: 760  VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PLKTDSAKPSQSFPPTGEKVSPFDS 818

Query: 529  HTKPAPKQTPRAPPKPKTSPRPR-IPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDV 587
               P P    +    P  S   +   Q  PV K  +   A+ K SP P+     P PK  
Sbjct: 819  KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK---PMPKGS 875

Query: 588  LLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTL---EETDQSTQEPFTTKI 644
              P  P P   Q+ P P +          SP P ++  + +L     TD    +P T + 
Sbjct: 876  PTPPGPRPTAGQTVPTPQQ----------SPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925

Query: 645  PRTTEL-----AKTTQAPHRFYTTVRPRTSDKPHIRPG----VKQAPRPS------GADR 689
              T +L     +  +QA +   T  +P     PH + G    +KQAP PS      G  +
Sbjct: 926  TVTGKLFGFGASIFSQASNLISTAGQP----GPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 690  NV---------SVDSTHPTKKPGTRR--PPLPPRPTHPR----RKPLP---PNNVTGKPG 731
            +          S+     TK P   +  P     PT  R    +KP P     ++T +P 
Sbjct: 982  STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041

Query: 732  SAGIISSGPITTPPLRSTPRPTGT-PLERIETDI--KQP----TVPASGEELENITDFSS 784
             A       +    L  +P+P  T PL + E +I  K P    T      ++ N+  F+ 
Sbjct: 1042 KA-------VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094

Query: 785  SP 786
            +P
Sbjct: 1095 TP 1096



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 83/375 (22%), Positives = 131/375 (34%), Gaps = 62/375 (16%)

Query: 314  ETLALPAESKTPEVEKISAR-PTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPT 372
            ++L+ PA  K P V     + P        P+  KPTT      S TT     KP I P+
Sbjct: 727  DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT-----KPDI-PS 780

Query: 373  AKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRAT 432
            +K+         Q+   +  + P  +D  + S S+  T +++     P  S+ + +P + 
Sbjct: 781  SKV---------QSQAEEKTTPPLKTDSAKPSQSFPPTGEKV----SPFDSKAIPRPASD 827

Query: 433  --LAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490
              +     P    K +    P  +   P   QT   P  P  +P PK   T P    +AG
Sbjct: 828  SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPTAG 886

Query: 491  TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKT---- 546
               P   +SP+P               +     S  +     APK  P  P +  T    
Sbjct: 887  QTVPTPQQSPKPQ--------------EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932

Query: 547  -------SPRPRIPQT--QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEV 597
                   S    +  T  QP P       A  K +P+P    T+  P             
Sbjct: 933  GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP---------KST 983

Query: 598  SQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAP 657
             Q+ PAP   + IP +   + +P+ E+L+   E+     +     K P   +    T  P
Sbjct: 984  GQAPPAP--AKSIP-VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040

Query: 658  HRFYTTVRPRTSDKP 672
             +     +   S KP
Sbjct: 1041 QKAVLPTKLEKSPKP 1055



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 123/559 (22%), Positives = 188/559 (33%), Gaps = 77/559 (13%)

Query: 319 PAESKTPEVEKISARPTTVTPETV---PRSTKPTTSSALDVSETTLASSEKPWIVPTAKI 375
           P  +K P  +  SA+P +  P +    P+   P   S      T   S +     P+A+ 
Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543

Query: 376 SEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAP 435
              +K    Q +T  V  S T S +P    + + ++ +      PKT   L      L  
Sbjct: 544 PSPAKP-SAQQSTKPV--SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL- 599

Query: 436 SETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKP-------ERTTS 488
                VP+K    T  E Q         T++ S     P P     K         +   
Sbjct: 600 ----HVPEKANFNTCTECQ---------TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646

Query: 489 AGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSP 548
            G + P +  SP+P   T AP  T           +  V+ + P P+QT    PK   +P
Sbjct: 647 GGDLAP-VPSSPQPKLKT-APVTT-----------TSAVSKSSPQPQQTS---PKKDAAP 690

Query: 549 RPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL---LPHKPYPEVSQSEPAPL 605
           +  + +  P PK P  +  +P    SP      P   D L    P K     S+ + AP+
Sbjct: 691 KQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV 749

Query: 606 ETRGIPFIPMISP-----SPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQ----- 655
                    M+ P     S S    +  +  +   +Q    T  P  T+ AK +Q     
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809

Query: 656 ----APHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPP 711
               +P       RP +  K    PG   +    G  +   V      KK  T+  P P 
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIISHPG--PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867

Query: 712 RPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI-ETDIKQPTVP 770
               P+  P PP    G   +AG     P  +P  +   R     L  I +    QPT P
Sbjct: 868 AKPMPKGSPTPP----GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923

Query: 771 ---ASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEE 827
               +G+         S  +      G+P   GPH    Q    +P     +  + P  +
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQP---GPH---SQSGPGAPMKQAPAPSQPPTSQ 977

Query: 828 ATEGNATSPPQNPPTNLTV 846
               +    P  P  ++ V
Sbjct: 978 GPPKSTGQAPPAPAKSIPV 996



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 89/403 (22%), Positives = 135/403 (33%), Gaps = 52/403 (12%)

Query: 327  VEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQT 386
            V  +S   +++    VP+   P      D   T L  SEK  +    K + +  +L+   
Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVA----DTVSTDLLISEKDPVKKAKKETGNGIILEVLE 2318

Query: 387  ATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPK---------TSRTLEQPR-ATLAPS 436
            A  D         +  +S++        + ++P K         +  T  Q + A+  PS
Sbjct: 2319 AYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPS 2378

Query: 437  ETPFV---PQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTIT 493
             +P V   P K   F        +  P      P  P   P P PP   P  T+   TI 
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL 2438

Query: 494  PKISKSPEPTWTTPAPG-------KTQFISLKPKIPLSPEVTHTKPAPKQTPRA------ 540
            PK   +     TT  P        +T  +     +P++   T   P     P +      
Sbjct: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498

Query: 541  ------PPKPKTSPRPRIPQTQPVPKVPQRVTAKPK----TSPS-----PEVSYTTPAPK 585
                  P KP  +P+P IPQ     + P  +  KP     TS           Y  P+P 
Sbjct: 2499 FTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPT 2558

Query: 586  DVLLPH--KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT----LEETDQSTQEP 639
              L PH  K  P  S+S         +P  P      S  +  T+        D  + EP
Sbjct: 2559 SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618

Query: 640  FTTKIPRTTELAKTTQAPHRFYTTVRPRT-SDKPHIRPGVKQA 681
              + +P  T +     +   FY +   +T S  P   P   QA
Sbjct: 2619 VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 75/330 (22%), Positives = 111/330 (33%), Gaps = 56/330 (16%)

Query: 292  VKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTS 351
            VK    L+   S   K  +  ++  +   E  TP ++  SA+P+   P T  +   P  S
Sbjct: 760  VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK-VSPFDS 818

Query: 352  SALD--VSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTA 409
             A+    S++ + S   P      +   D    + +        SP    +P    S T 
Sbjct: 819  KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878

Query: 410  TSDRILDSIPPKTSRTLEQPRATLAPSETP--FVPQKLEIFTSPEMQPTTPAPQQTTSI- 466
               R      P   +T+  P+ +  P E    F      I  +P+ QPTTP    T  + 
Sbjct: 879  PGPR------PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLF 932

Query: 467  ---------------------------PSTP-KRRPRPKPPRTKPERTTSAGTITPKISK 498
                                       P  P K+ P P  P T      S G   P  +K
Sbjct: 933  GFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 499  SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPV 558
            S      T AP   +   L+PK   +P V  T     +T + PP  K S        + +
Sbjct: 993  SIPVKKETKAPAAEK---LEPKAEQAPTVKRT-----ETEKKPPPIKDS--------KSL 1036

Query: 559  PKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588
               PQ+     K   SP+   T P  K  L
Sbjct: 1037 TAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 144/636 (22%), Positives = 236/636 (37%), Gaps = 107/636 (16%)

Query: 268  SPEKAPLGGVILVHLIIPGLNETTV---KLP-ASLMFEI-SDALKTQLAKNETLALP--- 319
            SP +AP+G           + E+T+   ++P ASL   + S A  T    + TL++P   
Sbjct: 2081 SPTQAPIG---------EDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVK 2131

Query: 320  --AESKTPEVE-KISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWI---VPTA 373
                  T E+E +     T    E +   +   T S    S T++  S+ P +   V + 
Sbjct: 2132 ITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSV 2191

Query: 374  KISEDSKVLQPQTATYDVFSSPTT-----SDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
              ++ S  +    +   V++ P        D  EIS S T     I+D  P + S +L++
Sbjct: 2192 CTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSS-TYFPGSIID-YPEEISVSLDR 2249

Query: 429  PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488
                   +    +   L    S  ++   P P+   +   +       K P  K ++ T 
Sbjct: 2250 TAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETG 2309

Query: 489  AGTITPKIS-----KSPEPTWTTPAPGKTQFI---SLKPKIPLSPEVTHTKPAPKQTPRA 540
             G I   +      K  E   T  +  +T F    S    +P+  +++ T     +T   
Sbjct: 2310 NGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET--- 2366

Query: 541  PPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT---SPSPEVSYTTPAPKDVLLPHKPYPE 596
                +  P  ++P   P V  +P    AKP+    S S ++S   P P     P  P P 
Sbjct: 2367 --FGQEKPASQLPSGSPSVSSLP----AKPRPFFRSSSLDISAQPPPPPP---PPPPPPP 2417

Query: 597  VSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP---RTTELAKT 653
                 P P      P  P  SP P      T L +   +   P TT  P     T L  T
Sbjct: 2418 PPPPPPPP------PLPPPTSPKP------TILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 654  TQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRP 713
                       R  T+  P + P  K +  PSG      +  TH   +P   +PP+ P+P
Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPP--KPSSIPSG------LVFTH---RPEPSKPPIAPKP 2514

Query: 714  THPR--RKPLPPNNVTGKPGSAGIISSG------------PITTPPL-----RSTPRPTG 754
              P+       P ++  KP    + SS             P  T PL     +S+PR + 
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574

Query: 755  TPLER--IETDIKQPTVPASGEELENITDFS-SSPTRETDPLGKPRFKGPHVRYIQKPDN 811
            +  E   + T   +P  P      + IT +   SP+++   +       P V  ++ P +
Sbjct: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634

Query: 812  SPCS--ITDSVKRFPKEEATEGNATSPPQNPPTNLT 845
            S  +  I+ +++ F    AT   A S  Q  PT++T
Sbjct: 2635 SEQTFYISGALQTF---SATPVTAPSSFQAAPTSVT 2667



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 130/646 (20%), Positives = 213/646 (32%), Gaps = 96/646 (14%)

Query: 312  KNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVP 371
            K +   +P  S TP   + +A  T  TP+  P+  + +   +L++   T A   +P    
Sbjct: 865  KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP---T 921

Query: 372  TAKISEDSKVLQPQTATYDVFS---SPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
            T + +   K+     + +   S   S      P       A   +      P TS+   +
Sbjct: 922  TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 429  PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 488
                  P+    +P K E   +P  +   P  +Q  ++  T   +   KPP  K  ++ +
Sbjct: 982  STGQAPPAPAKSIPVKKET-KAPAAEKLEPKAEQAPTVKRTETEK---KPPPIKDSKSLT 1037

Query: 489  A----GTITPKISKSPEPTWTTPAPGKTQFISLK--PKIPLSPEVTHT-------KPAPK 535
            A      +  K+ KSP+P  T P       I  K  P      E  +         P P 
Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097

Query: 536  QT--------------------------PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569
             T                          P AP  PK SP P      P     Q+    P
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP-----VPTESSSQKTAVPP 1152

Query: 570  --KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQ- 626
              K     E    T A K +L   +   E    E  P         PM++    QEE + 
Sbjct: 1153 QVKLVKKQEQEVKTEAEKVIL---EKVKETLSMEKIP---------PMVTTDQKQEESKL 1200

Query: 627  -----TTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQA 681
                 + L+E     +E     IP   ++    + P       +P   DK  +      A
Sbjct: 1201 EKDKASALQEKKPLPEE--KKLIPEEEKIRSEEKKP--LLEEKKPTPEDKKLLPEAKTSA 1256

Query: 682  PRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRK--PLPPNNVTGKPGSAGIISSG 739
            P     D   S       K  G   P        P+ K   LP    +G P S  +    
Sbjct: 1257 PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP----SGTPQS--LPKED 1310

Query: 740  PITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFK 799
              TT  ++  P+P  T     + D  +P    + +E +     SS   +    L    + 
Sbjct: 1311 DKTTKTIKEQPQPPCT----AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366

Query: 800  GPHVRYI--QKPDNSPCSITDSVKRFPKEE-ATEGNATSPPQNPPTNLTVVTVEGCPSFV 856
               +     + P   P    D +K   K+  + E + +SP        TV+++    +  
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426

Query: 857  ILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLK 902
            + D EK  ++  T+   +S E      K +S+  T +   + E +K
Sbjct: 1427 LAD-EK--SEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK 1469



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 33/321 (10%)

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPT-----AKISE--DSKVLQPQTATYDVFSSPTT 397
            S +  T  ++D S  T    +  W +PT     A++ +  DS     +T      SS   
Sbjct: 3459 SRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAV 3518

Query: 398  SDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTT 457
                EIS            SI  +    +E  +   AP +T +    L   T  +    +
Sbjct: 3519 QTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKT-YKGGSLGCQTEADSDTQS 3577

Query: 458  PAPQQTTSIPSTPKRRPRPKPPR---TKPERTTSAGTITPKISKSPEPTWTTPAPGKTQF 514
            P   Q  S  S PK + RP P     +   R  S   + P   KSP+  ++  +P     
Sbjct: 3578 P---QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP----- 3629

Query: 515  ISLKPKIPL-SPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQP-VPKVPQRVTAKPKT- 571
              L P   L S  V + KP P     +P K       ++P   P   K+ QR  + PK  
Sbjct: 3630 --LSPGKALESAFVPYEKPLPDDI--SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685

Query: 572  SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631
            SP+ + S   P         K    ++ S       R +P       +P  EE+ T  + 
Sbjct: 3686 SPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLP-------NPPPEEISTGTQS 3738

Query: 632  TDQSTQEPFTTKIPRTTELAK 652
            T  +       +I RT  +A+
Sbjct: 3739 TFSTMGTVSRRRICRTNTMAR 3759



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 25/152 (16%)

Query: 411  SDRILDSIPP---KTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIP 467
            SD  + S  P   ++   +E+PR       + F+P + +   S  + PT+P  Q   S P
Sbjct: 3835 SDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQT-ESQLVPPTSPYTQYQYSSP 3893

Query: 468  STPKRRP-----------------RPKPPRTKPE-RTTSAGTITPKISKSPEPTWTTPAP 509
            + P + P                 +  P +T+P  +  +  + TP++  +P P  +   P
Sbjct: 3894 ALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLP 3953

Query: 510  GKTQFISLKPK---IPLSPEVTHTKPAPKQTP 538
             +   I  KP+   + L P++T      +  P
Sbjct: 3954 SQMMVIQQKPRQTTLYLEPKITSNYEVIRNQP 3985



 Score = 34.3 bits (77), Expect = 0.65
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 9/82 (10%)

Query: 639 PFTTKIPRTTE--LAKTTQAPHRFYTTVRPRTSDKPH--IRPGVKQAPRPSGADRNVSVD 694
           P  T IP   E  L++ ++   R    V  R    P   + P   ++P      R   +D
Sbjct: 32  PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESP---SMHRKQELD 88

Query: 695 STHPTKKPGTRRPPLPPRPTHP 716
           S+HP K+ G  RPP P RP  P
Sbjct: 89  SSHPPKQSG--RPPDPGRPAQP 108



 Score = 34.3 bits (77), Expect = 0.65
 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 526  EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA-P 584
            EV+ T+P   ++     +P+T+P+    Q  P P+        P TSP  +  Y++PA P
Sbjct: 3838 EVSSTRPTRIESQHGIERPRTAPQTEFSQFIP-PQTQTESQLVPPTSPYTQYQYSSPALP 3896

Query: 585  KDVLLPHKP----------YPEVS--QSEPAPLETRGIPFIPMISPSPSQE 623
                  +            + +VS  Q++P       + F P + P+P+ +
Sbjct: 3897 TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQ 3947


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 80.5 bits (197), Expect = 8e-15
 Identities = 114/457 (24%), Positives = 165/457 (36%), Gaps = 60/457 (13%)

Query: 319  PAESKTPEVEKISARPTTVTPET-------VPRSTKPTTSSALDVSETTLASSEKPWIVP 371
            P    TP++    +RPT V P T       +  ST P+ SS    + T  + ++ P +  
Sbjct: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSS----NHTPASPTQTPLLPA 1257

Query: 372  TAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRA 431
            T   S+        TA+      PTT+  P+ +     T+   L S   K + T    RA
Sbjct: 1258 TLTSSKP-------TASSGEPPRPTTAVTPQATSGLPPTAT--LRSTATKPTVTQATTRA 1308

Query: 432  TLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP---------PRTK 482
            T A + +P      +  T   M   TPA   T+  P+ PK   +  P         PR  
Sbjct: 1309 T-ASTASPATTSTAQSTTRTTMTLPTPATSGTS--PTLPKSTNQELPGTTATQTTGPRPT 1365

Query: 483  PERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPP 542
            P  TT   T  P     P  T TT     T++ +     P +P  TH+ P    +P    
Sbjct: 1366 PASTTGPTTPQPGQPTRPTATETTQTRTTTEYTT-----PQTPHTTHSPPT-AGSPVPST 1419

Query: 543  KPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLP-HKPYPEVSQSE 601
             P T+       T P P  P+  T  P   P    S  TP+   V+ P H      + + 
Sbjct: 1420 GPVTATSFHATTTYPTPSHPE--TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNH 1477

Query: 602  PAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFY 661
             AP  T          P P      TTL+ T  +   P  T     T  A ++ + ++  
Sbjct: 1478 SAPTGT---------IPPP------TTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTP 1522

Query: 662  TTVRPRTSD--KPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRK 719
            T++   TS    P + P       P+           H T    + RPP PP  TH    
Sbjct: 1523 TSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAH-TNSATSSRPP-PPFTTHSPPT 1580

Query: 720  PLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTP 756
               P + TG   +    ++    TP    T  PT  P
Sbjct: 1581 GSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVP 1617



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 98/412 (23%), Positives = 141/412 (34%), Gaps = 46/412 (11%)

Query: 451  PEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPG 510
            P M PTTP P  T  +P+T  R     P +  P   TS  TI    S  P P+       
Sbjct: 1195 PCMPPTTPQPPTTPQLPTTGSR-----PTQVWPMTGTST-TIGLLSSTGPSPSSNHTPAS 1248

Query: 511  KTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK 570
             TQ        PL P  T T   P  +   PP+P T+  P+     P     +    KP 
Sbjct: 1249 PTQ-------TPLLP-ATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT 1300

Query: 571  TSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLE 630
             + +   +  + A        +     + + P P  +   P +P    S +QE   TT  
Sbjct: 1301 VTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLP---KSTNQELPGTTAT 1357

Query: 631  ETDQSTQEPFTTKIPRTTELAKTTQ----APHRFYTTVRPRTSDKPHIRPGVKQAPRPSG 686
            +T      P +T  P T +  + T+       +  TT    T   PH       A  P  
Sbjct: 1358 QTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVP 1417

Query: 687  ADRNVSVDSTHPTKKPGTRRPPLPPRPTH--PRRKPL--PPNNVTGKPGSAGIISSGPIT 742
            +   V+  S H T    T   P    PTH  P    L  P  +    P  A + +S    
Sbjct: 1418 STGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNH 1477

Query: 743  TPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPH 802
            + P  + P PT T      T    P  P +    +  + FS++ T        P     H
Sbjct: 1478 SAPTGTIPPPT-TLKATGSTHTAPPITPTTSGTSQAHSSFSTNKT--------PTSLHSH 1528

Query: 803  VRYIQKPDNSPCSI-------TDSVKRFPKEEATEGNATSPP-----QNPPT 842
                  P+ +P S        T +  R P        ++ PP      +PPT
Sbjct: 1529 TSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPT 1580



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 163/738 (22%), Positives = 238/738 (32%), Gaps = 123/738 (16%)

Query: 289  ETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPT--TVTPETVPRST 346
            ++T +   +L    +      L K+    LP  + T   +    RPT  + T  T P+  
Sbjct: 1322 QSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTAT---QTTGPRPTPASTTGPTTPQPG 1378

Query: 347  KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDS 406
            +PT  +A   +ETT   +   +  P    +  S    P TA      SP  S  P  + S
Sbjct: 1379 QPTRPTA---TETTQTRTTTEYTTPQTPHTTHS----PPTA-----GSPVPSTGPVTATS 1426

Query: 407  YTATSDRILDSIPPKTSRTLEQPRAT--LAPS-ETPFVPQKLEIFTSPEMQ--PTTPAPQ 461
            + AT+     S P  T  T   P +T  + PS  T   P   ++ TS      PT   P 
Sbjct: 1427 FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP 1486

Query: 462  QTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKS----------PEPTWT-----T 506
             TT   +       P  P T       +   T K   S          PE T T     T
Sbjct: 1487 PTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTIT 1546

Query: 507  PAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPK---------PKTSPRPRIPQTQP 557
            P P  T+    +  +  +   T ++P P  T  +PP          P T+   +   T P
Sbjct: 1547 PNPTSTR---TRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYP 1603

Query: 558  VPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQS----------EPAPLET 607
             P  PQ  T  P   P    S  TP+   V+ P       S S           P  L+ 
Sbjct: 1604 TPSHPQ--TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKA 1661

Query: 608  RG----IPFIPMISPSPSQ---------------------EELQTTLEETDQSTQEPFTT 642
             G     P + + +   SQ                        + T   T   T  P +T
Sbjct: 1662 TGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST 1721

Query: 643  KIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKP 702
              P  T     T      ++T +  TS   H        P  +      S+   H +   
Sbjct: 1722 GTPPMTVTTSGTSQSRSSFSTAK--TSTSLHSHTSSTHHPEVTSTS-TTSITPNHTST-- 1776

Query: 703  GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-----------TPPLRSTPR 751
            GTR P          R P P    +   G+  I S+GP+T           TP    T  
Sbjct: 1777 GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTL 1836

Query: 752  PTGTP--LERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG-PHVRYIQK 808
            PT  P     + T      +  +  ++       S PT    P    +  G  H      
Sbjct: 1837 PTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMT 1896

Query: 809  PDNSPCSITDSVKRFPKEEAT---EGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLN 865
            P  S  S + S     K   +     ++T  P+  PT+ T +T    P         P+ 
Sbjct: 1897 PTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNIT----PKHTSTGTRTPVA 1952

Query: 866  DTV--------TEYEVISRENGS--FSGKNKSIQMTNQTFSTVEN-LKPNTSYEFQVKPK 914
             T         T +   S   GS  FS        + QT +T      P T+    V P 
Sbjct: 1953 HTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPF 2012

Query: 915  NPLGEGPVSNTVAFSTES 932
            +     P ++TV  +T +
Sbjct: 2013 STSLVTPSTHTVIITTHT 2030



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 130/592 (21%), Positives = 202/592 (34%), Gaps = 73/592 (12%)

Query: 315  TLALPAESKTPEVEKISARPT-TVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTA 373
            T+  P  ++      I + PT T+ P T  ++T  +T +A  ++ TT  +S+    + TA
Sbjct: 1630 TVITPTHAQMATSASIHSMPTGTIPPPTTLKAT-GSTHTAPTMTLTTSGTSQALSSLNTA 1688

Query: 374  K--------ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRT 425
            K         S         T+T ++  +PT++  P ++ + + TS         KTS +
Sbjct: 1689 KTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTS 1748

Query: 426  L-------EQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP 478
            L         P  T + S T   P      T   +  TT A       P T    P    
Sbjct: 1749 LHSHTSSTHHPEVT-STSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTT 1807

Query: 479  P--RTKPERTTSAGTITPKISKS-PEPTWTTPAPG-KTQFISLKPKIPLSPEVTHTKPAP 534
            P   T P   TS  T T   + S P  T  T  P   T  ++      + P  THT+ A 
Sbjct: 1808 PISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIP--THTQMAT 1865

Query: 535  KQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPY 594
              +  + P     P   I  T      P        TS SP  S++T      L    PY
Sbjct: 1866 SASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPS-SFSTAKTSTSL----PY 1920

Query: 595  PEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTE----- 649
               S   P    T      P  + + ++  +  T   +      PFTT  P T       
Sbjct: 1921 HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS 1980

Query: 650  ----LAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS------GADRNVSVDSTHPT 699
                 A + Q    + T   P+T+   H+ P       PS           ++  ++  +
Sbjct: 1981 TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS 2040

Query: 700  KKPGTRRPPLPPRPTHPRRKPLPPNNVTGK------------PGSAGIISSGPITTPPLR 747
               GT  PP   + T       PP  VT                S+  ISS   +  P  
Sbjct: 2041 TPTGTVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSS--SWLPQN 2097

Query: 748  STPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET-------DPLGKPRFKG 800
            S+ RP  +P+      +   T P S    +  + FS SP+  +            P+   
Sbjct: 2098 SSSRPPSSPITTQLPHLSSATTPVSTTN-QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSS 2156

Query: 801  PHV----RYIQKPDNSPCSITDSVKRFPKEEATEGNATSP--PQNPPTNLTV 846
            P V     ++  P +S    + S         T   + SP  P +P  + T+
Sbjct: 2157 PSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 119/524 (22%), Positives = 189/524 (36%), Gaps = 76/524 (14%)

Query: 315  TLALPAESKTPEVEKISARPT-TVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTA 373
            T+ +P  ++      I + PT T+ P T  ++T  +T +A  ++ TT  +S+ P    TA
Sbjct: 1854 TVIIPTHTQMATSASIHSMPTGTIPPPTTIKATG-STHTAPPMTPTTSGTSQSPSSFSTA 1912

Query: 374  KISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATL 433
            K S         T   +V  + TT+  P+   + T T   +  +    +SR L  P  T 
Sbjct: 1913 KTSTSLPYHTSSTHHPEVTPTSTTNITPK--HTSTGTRTPVAHTTSASSSR-LPTPFTTH 1969

Query: 434  AP--SETPFV---PQKLEIFTSPEMQPTTPAPQQT--TSIPSTPKRRPRPKPP----RTK 482
            +P    +PF    P     F +    PT   PQ T  T +P        P        T 
Sbjct: 1970 SPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTH 2029

Query: 483  PERTTSA-------GTITPKIS--------KSPEPTWTTPAPGKTQFISLKPKIPLSPEV 527
             +  TSA       GT+ P  +         +P  T TT    +T   S       S  +
Sbjct: 2030 TQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTH-SSFSTATASSSFI 2088

Query: 528  THTKPAPKQTPRAPP-KPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKD 586
            + +   P+ +   PP  P T+  P +           ++++    SPS   + ++  P  
Sbjct: 2089 SSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSS 2148

Query: 587  VLLPHKPYPEVSQSE---PAPLETRGI-----------PFIPMISPS---PSQEELQTTL 629
               P    P V  S     AP+ +  +           P    +S S   PS     TT+
Sbjct: 2149 HSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208

Query: 630  EET-DQSTQEPFTTK--IPRTTELAKTTQAPHRFYTTV----RPRTSDKPHIRPGVKQAP 682
              T   +   PFT    +P +T     T + H   +T+     PRT+   H  P      
Sbjct: 2209 RATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSS-- 2266

Query: 683  RPSGADRNVSVDSTHPTK-----KPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIIS 737
              S   R+ S+ +  PT        G    P  P      R P P  + T +  ++ + +
Sbjct: 2267 -QSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTA 2325

Query: 738  SGPI-TTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENIT 780
             G    + P+ S   PT T           P V +  E+ E IT
Sbjct: 2326 HGSTPASAPVSSLGTPTPT----------SPGVCSVREQQEEIT 2359



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 60/251 (23%), Positives = 87/251 (34%), Gaps = 14/251 (5%)

Query: 698  PTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISS-GPITTPPLRSTP-RPTGT 755
            P   P T +PP  P+      +P     +TG   + G++SS GP  +P    TP  PT T
Sbjct: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGP--SPSSNHTPASPTQT 1252

Query: 756  PLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCS 815
            PL        +PT  +SGE     T  +   T    P    R         Q    +  S
Sbjct: 1253 PLLPATLTSSKPTA-SSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311

Query: 816  ITDSVKRFPKEEATEGNATSP-PQNPPTNLTV--VTVEGCPSFVILDWEKPLNDTVTEYE 872
                      +  T    T P P    T+ T+   T +  P         P     +   
Sbjct: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371

Query: 873  VISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPK--NPL-GEGPVSNTVAFS 929
              + + G       +   T QT +T E   P T +     P   +P+   GPV+ T +F 
Sbjct: 1372 PTTPQPG--QPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTAT-SFH 1428

Query: 930  TESADPRVSEP 940
              +  P  S P
Sbjct: 1429 ATTTYPTPSHP 1439


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 143/641 (22%), Positives = 222/641 (34%), Gaps = 61/641 (9%)

Query: 328 EKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISED-----SKVL 382
           E I  R  T    T P    PT +  +  +E T     +P        +E+     ++  
Sbjct: 322 EPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 381

Query: 383 QPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVP 442
           +    T +  ++P+ ++  E  +     +D+   S    T      P A    + +P  P
Sbjct: 382 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP 441

Query: 443 QKLEIFTSPEMQPTTPA-PQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPE 501
            +    T+ E    +PA P +     +  K    P  P T+   TT+    TP  ++  E
Sbjct: 442 TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEP-TENRETTANEKTTPSPAEPTE 500

Query: 502 PTWTTP-APGKTQFISLKP-----KIPLSPEVTHTKPA-PKQTPRAPPKPKTSPRPRIPQ 554
               TP A  KT   S +P     + PL+ E T   PA P +        KT+P P    
Sbjct: 501 NGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSP---- 556

Query: 555 TQPVPKVPQRVTAKPKTSPS----PEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGI 610
            +P     +   A  KT+PS     E    TP   +        P     E  PL     
Sbjct: 557 AEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEP-TEHEERTPLANENT 615

Query: 611 PFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT-S 669
              P     P++   +T  E T  S   P  T+    T   KTT  P    T  R RT +
Sbjct: 616 TPSP---AEPTENRERTANENTTPSPAGP--TENREMTANEKTTLFPAE-PTENRERTAN 669

Query: 670 DKPHIRPG--VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 727
           +K    P    +   R   A+   +  S  PT+              H  R PL   N T
Sbjct: 670 EKTTSSPAEPTENGQRTPFANEKTTSSSAEPTE--------------HGERTPLANENTT 715

Query: 728 GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPT 787
             P      +     T   ++TP P   P E  E    + T P+  +  EN      +  
Sbjct: 716 LSPAEP---TENRERTANEKTTPFP-AEPTENRERTANENTTPSPAQPTENGDRTPLANE 771

Query: 788 RETDPLGKPRFKGPHVRYI-QKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTV 846
           + T  L +P   G    +  +K  +S    T+  +R P       N TS P  P  N   
Sbjct: 772 KTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTP---LANENTTSSPAEPTENRER 828

Query: 847 VTVEGC---PSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKP 903
              E     P+    + E   N+  T +     EN  ++  N++  ++    +  E + P
Sbjct: 829 TANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTA-NENTTLSPAEPTEHEEMTP 887

Query: 904 NTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAG 944
             + +  + P  P   G       F+ E   P  +EP   G
Sbjct: 888 LANEKTTLSPAEPTENG---ERTPFTNEKTTPSSAEPTEHG 925



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 162/705 (22%), Positives = 248/705 (35%), Gaps = 109/705 (15%)

Query: 314  ETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALD--VSETTLASSEKPWI-- 369
            ET A    + +P VE    R TT   +T P   +PT +       +E T +SS +P    
Sbjct: 465  ETTANEKTTLSP-VEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHG 523

Query: 370  --VPTAKISEDSKVLQP---QTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSR 424
               P A  +      +P   +  T +  ++P+ ++  E  D     +++   S+   T  
Sbjct: 524  ERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTEN 583

Query: 425  TLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAP------------QQTTSIPSTPKR 472
                P A    + +   P + E  T    + TTP+P            + TT  P+ P  
Sbjct: 584  GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTE 643

Query: 473  RPR----------PKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKP--- 519
                         P  P    ERT +  T +     +     T  A  KT   S +P   
Sbjct: 644  NREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEH 703

Query: 520  --KIPLSPEVTHTKPA-PKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPE 576
              + PL+ E T   PA P +        KT+P P  P         +  TA   T+PSP 
Sbjct: 704  GERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTEN------RERTANENTTPSP- 756

Query: 577  VSYTTPAPKDVLLPHKPYPEVSQSEPAPLET-RGIPFI----PMISPSPSQEELQTTL-- 629
               T    +  L   K  P +++    P E  +  PF        S  P++   +T L  
Sbjct: 757  AQPTENGDRTPLANEKTTPSLAE----PTENGKRTPFANEKTTSSSAEPTEHAERTPLAN 812

Query: 630  EETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADR 689
            E T  S  EP  T+    T   KTTQ P           ++K    P      R   A+ 
Sbjct: 813  ENTTSSPAEP--TENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANE 870

Query: 690  NVSVDSTHPTKKP-----GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGP---- 740
            N ++    PT+          +  L P       +  P  N    P SA     G     
Sbjct: 871  NTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPL 930

Query: 741  ---ITTPPL-------------RSTPRPTGTPLERIETDIKQPTVPASGEELEN------ 778
               ITTP               ++TP P   P E  ET + + T P+S E  EN      
Sbjct: 931  ANEITTPSRAEPTEHGERIANEKATPSPA-KPTEHGETTVNEDTTPSSAEPTENGERTPL 989

Query: 779  -ITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPP 837
               + ++SPT  T+        G      +K   SP   T+  +R P   A E    SP 
Sbjct: 990  ANENTTTSPTESTE-------HGERTAN-EKTTPSPAEPTEHGERTP--SANEKTIPSPA 1039

Query: 838  QNPPTNLTVVTVEGCPSFVILDWEKPLNDTV-TEYEVISRENGSFSGKNKSIQMTNQTFS 896
            +  PT    +T    PS        P+  T   E   ++ E  + S +  + +   +T S
Sbjct: 1040 K--PTEHEEMT----PSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPT-EHGAKTTS 1092

Query: 897  TVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPV 941
              E + P+ +   +   +       ++++ A STE  D   S  V
Sbjct: 1093 ANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANV 1137



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 95/441 (21%), Positives = 140/441 (31%), Gaps = 38/441 (8%)

Query: 458 PAPQQTTSIPSTPKRR--PRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFI 515
           PA   TT   S  K+   P PK      + TT   T+T K  K+  P          + +
Sbjct: 142 PADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPL--------EKSM 193

Query: 516 SLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSP 575
           S   K   S   T T        +   K  + P     +     K   + T  P+ S   
Sbjct: 194 STLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPE----KITAASKTTYKTTGTPEESEKT 249

Query: 576 EVSYTTPAPKDVLLPHK-------PYPEVSQSEPAPLETRGIPFIPMISPS---PSQEEL 625
           E S TT A   +L              E++QS   P E  G       +PS   P++   
Sbjct: 250 EDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRE 309

Query: 626 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPS 685
           +T  E T  S  EP   +    T    T   P           ++   + P         
Sbjct: 310 RTANENTTLSPAEPIENR--ERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGER 367

Query: 686 GADRNVSVDSTHPT----KKPGTRRPPLPPRPT-HPRRKPLPPNNVTGKPGSAGIISSGP 740
            A+ N +     PT    +       P P  PT H  R P   +  T    SA     G 
Sbjct: 368 TANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTS--SSAESTEHGE 425

Query: 741 ITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKG 800
            T     +T      P E  E    + T P+     EN  + +++      P+     + 
Sbjct: 426 RTPLANENTTPSPAEPTENRERTANENTTPSPAGPTEN-RETTANEKTTLSPVEPTENRE 484

Query: 801 PHVRYIQKPDNSPCSITDSVKR--FPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVIL 858
                 +K   SP   T++ +R  F  E+ T  +A        T L        P+    
Sbjct: 485 TTAN--EKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTE 542

Query: 859 DWEKPLNDTVTEYEVISRENG 879
           + E+  N+  T       ENG
Sbjct: 543 NRERTANEKTTPSPAEPTENG 563



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 59/265 (22%), Positives = 101/265 (38%), Gaps = 41/265 (15%)

Query: 288  NETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTK 347
            NE T   PA          +T  A  +T+  PA  K  E E+++    +    T P   K
Sbjct: 1010 NEKTTPSPAE---PTEHGERTPSANEKTIPSPA--KPTEHEEMTP---SANENTTPSPVK 1061

Query: 348  PTTSSALDVSETTLASSEKPWIVPT------AKISEDSKVLQPQTATYDVFSSPTTSDEP 401
            PT     +  E T  ++EK  + P       AK +  ++ + P  A        TTS   
Sbjct: 1062 PT-----EHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPND 1116

Query: 402  EISDSYT--------ATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEM 453
            +I+ S          ATS  ++   P +  +  +  R TLA  +   V +K    ++   
Sbjct: 1117 KITSSAAESTEHRDRATSANVITPAPAEPIKHAK--RTTLAHEKMTQVTEK----STEHP 1170

Query: 454  QPTTPAPQQTTSIPSTPK--------RRPRPKPPRTKPERTTSAGTITPKISKSPEPTWT 505
            + TT   ++TT  P  P          + +  P   KP       T+T +  K+P  +  
Sbjct: 1171 EKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTE 1230

Query: 506  TPAPGKTQFISLKPKIPLSPEVTHT 530
             P        ++KP + ++ + + T
Sbjct: 1231 NPEKTAAVTKTIKPSVKVTGDKSLT 1255


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 154/665 (23%), Positives = 234/665 (35%), Gaps = 114/665 (17%)

Query: 319  PAE--SKTPEVEKISA----RPTTVTPETVPRSTKPTTSSALDVSETTLAS--------- 363
            PAE  S+    EK+S      P    P TVP +  P        S+  LA          
Sbjct: 1013 PAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLP 1072

Query: 364  SEKPWI----------VPTAKISEDSKVLQPQTATYDVFSS-----PTTSDEPEISDSYT 408
            S KP +           P A +S + +   P+       SS     P TS  PE   S T
Sbjct: 1073 SIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPS-T 1131

Query: 409  ATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPS 468
            +T+  +     P +  T  +   +   +  P VP      T+PE+QP+T   Q  TS P+
Sbjct: 1132 STAQPVTPK--PTSQATRSRTNRSSVKTPEPVVP------TAPELQPSTSTDQPVTSEPT 1183

Query: 469  TPKRRPRPKPPRTKPERTT---------SAGTITPKISKSPEPTWTTPAPGKTQFISLKP 519
            +   R R      K   T          S  T  P ++  P    T     ++   + +P
Sbjct: 1184 SQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP-VTSEPTSQATRGRKNRSSVKTPEP 1242

Query: 520  KIPLSPEVTHTKPAPKQTPRAPPKPKTSPR-------------PRIPQTQPVPKVPQRVT 566
             +P +PE+  +    +     P    T  R             P  P+ +P     + VT
Sbjct: 1243 VVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVT 1302

Query: 567  AKP--KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624
             KP  +T+ S     +   P+ V +P  P  ++S S   P           ++P P+   
Sbjct: 1303 PKPTSRTTRSRTNMSSVKTPETV-VPTAPELQISTSTDQP-----------VTPKPTS-- 1348

Query: 625  LQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRP 684
             +TT   T+ S+ +   + +P   EL  +T       +T +P T + P  R    +  R 
Sbjct: 1349 -RTTRSRTNMSSVKNPESTVPIAPELPPST-------STEQPVTPE-PTSRATRGRKNRS 1399

Query: 685  SGADRNVSVDSTHPTKKPGTRR-PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITT 743
            SG      V  T P  +P T    P+ P PT    +     +    P +  ++ + P   
Sbjct: 1400 SGKTPETLV-PTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPET--VVPTAPELQ 1456

Query: 744  PPLRS----TPRPTG------TPLERIET-DIKQPTVPASGEELENITDFSSSPTRETDP 792
            P   +    TP PT       T    ++T +   PT P            +S PT  T  
Sbjct: 1457 PSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTR 1516

Query: 793  LGKPR--FKGPHVRYIQKPDNSPCSITDS-VKRFPKEEATEGNATSPPQNPPTNLTVVTV 849
              K R   K P       P+  P + TD  V   P   AT G         P ++  +  
Sbjct: 1517 GRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1576

Query: 850  EGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEF 909
            E  PS          N  VT  E  SR     + ++ S++       T     P TS + 
Sbjct: 1577 ELQPS-------TSRNQLVTP-EPTSRATRCRTNRS-SVKTPEPVVPTAPEPHPTTSTDQ 1627

Query: 910  QVKPK 914
             V PK
Sbjct: 1628 PVTPK 1632



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 134/537 (24%), Positives = 202/537 (37%), Gaps = 77/537 (14%)

Query: 323  KTPEVEKISA---RPTTVTPETV-PRSTKPTTSSALDVSETTLASSEKPWIVPTA-KISE 377
            KTPE    +A   RP+T T   V P+ T  TT S  ++S      +    +VPTA ++  
Sbjct: 1279 KTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET----VVPTAPELQI 1334

Query: 378  DSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSD-RILDSIPPKTSRTLEQP------- 429
             +   QP T      +S TT     +S      S   I   +PP TS   EQP       
Sbjct: 1335 STSTDQPVTPKP---TSRTTRSRTNMSSVKNPESTVPIAPELPPSTST--EQPVTPEPTS 1389

Query: 430  RATLAPSETPF--VPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTT 487
            RAT           P+ L + T+P+++P+T   Q  T  P++   R R      K   T 
Sbjct: 1390 RATRGRKNRSSGKTPETL-VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETV 1448

Query: 488  --SAGTITPKISK----SPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTP 538
              +A  + P  S     +PEPT +    G+T   S+K     +P +PE+  +    +   
Sbjct: 1449 VPTAPELQPSTSTDQPVTPEPT-SQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1507

Query: 539  RAPPKPKTSPR-------------PRIPQTQPVPKVPQRVTAKPKTSPSP-EVSYTTPAP 584
              P    T  R             P  P+ QP     Q VT +P +  +    + ++   
Sbjct: 1508 SEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKT 1567

Query: 585  KDVLLPHKP--YPEVSQSE---PAPLETRGIPFIPMISPSPSQEELQTTLEETDQ--STQ 637
             + ++P  P   P  S+++   P P  +R        S   + E +  T  E     ST 
Sbjct: 1568 PESIVPIAPELQPSTSRNQLVTPEPT-SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTD 1626

Query: 638  EPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRP------------GVKQAPRPS 685
            +P T K+       KT ++  +    V P  SD     P            G +     S
Sbjct: 1627 QPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRS 1686

Query: 686  GADRNVSVDSTHPTKKPGTRRPPLPPRP-THPRRKPLPPNNVTGKPGS-AGIISSGPITT 743
               R + V +T   + P T   P+ P P T P    +      G PGS A  I   P + 
Sbjct: 1687 STVRAMPVPTTPEFQSPVTTDQPISPEPITQP--SCIKRQRAAGNPGSLAAPIDHKPCSA 1744

Query: 744  P--PLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRF 798
            P  P     R       R    +     PAS + LE  T   +S  ++ +P G+ RF
Sbjct: 1745 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLE--TPIHASQIQKVEPAGRSRF 1799



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 108/492 (21%), Positives = 173/492 (35%), Gaps = 101/492 (20%)

Query: 483  PERTTSAGTITPKISKSPEPTWTTP-------APGKTQFISLKPKIPLSPEVTHTKPAPK 535
            PE    AG + P  + +P P+ +         +P + Q   L  K+P + + +  + A K
Sbjct: 967  PEPGVGAGDL-PGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEK 1025

Query: 536  QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYP 595
             +      P     P +P+    P+ P    ++   +P P +S   P+ K  +   K   
Sbjct: 1026 VSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTV--RKTRQ 1083

Query: 596  EVSQSEP-APLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTT 654
            + SQ  P APL +   PF P       + +++T   ++ + T  P T+  P         
Sbjct: 1084 DGSQEAPEAPLSSELEPFHP-------KPKIRT--RKSSRMTPFPATSAAPE-------- 1126

Query: 655  QAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPT 714
              PH   +T +P T             P+P          ++  T+    R     P P 
Sbjct: 1127 --PHPSTSTAQPVT-------------PKP----------TSQATRSRTNRSSVKTPEPV 1161

Query: 715  HPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQP-TVPASG 773
             P    L P+  T +          P+T+ P     R       +  + +K P TV  + 
Sbjct: 1162 VPTAPELQPSTSTDQ----------PVTSEPTSQVTRG-----RKSRSSVKTPETVVPTA 1206

Query: 774  EELENITD----FSSSPTRETDPLGKPR--FKGPHVRYIQKPDNSPCSITDS-VKRFPKE 826
             EL+  T      +S PT +     K R   K P       P+  P + TD  V   P  
Sbjct: 1207 LELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266

Query: 827  EATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNK 886
            +AT G         P  +     E  PS      ++P+    T     SR N S      
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPS---TSTDRPVTPKPTSRTTRSRTNMS------ 1317

Query: 887  SIQMTNQTFSTVENLKPNTSYEFQVKP----------------KNPLGEGPVSNTVAFST 930
            S++       T   L+ +TS +  V P                KNP    P++  +  ST
Sbjct: 1318 SVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1377

Query: 931  ESADPRVSEPVS 942
             +  P   EP S
Sbjct: 1378 STEQPVTPEPTS 1389



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 65/315 (20%), Positives = 119/315 (37%), Gaps = 32/315 (10%)

Query: 288  NETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPE-TVPRST 346
            N ++VK P S++  I+  L+   ++N+ +     S+       + R +  TPE  VP + 
Sbjct: 1561 NRSSVKTPESIV-PIAPELQPSTSRNQLVTPEPTSRATRCR--TNRSSVKTPEPVVPTAP 1617

Query: 347  KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEI--- 403
            +P  +++ D   T   +S            +  K ++P  +  + F+    S  PE    
Sbjct: 1618 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQ 1677

Query: 404  -SDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQ 462
               S T  S  +  ++P  T+   + P  T    + P  P+ +   T P       A   
Sbjct: 1678 GGQSKTLRSSTVR-AMPVPTTPEFQSPVTT----DQPISPEPI---TQPSCIKRQRAAGN 1729

Query: 463  TTSIPSTPKRRP--RPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKT-----QFI 515
              S+ +    +P   P  P+++  R    G +    S +  P   +P   +T     Q  
Sbjct: 1730 PGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQ 1789

Query: 516  SLKPK------IPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 569
             ++P         L P+ + ++     T  +PP  K   R  + Q   + K  +  TA+ 
Sbjct: 1790 KVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAE- 1848

Query: 570  KTSPSPEVSYTTPAP 584
               P  E    TP P
Sbjct: 1849 --KPGKEEDVVTPKP 1861


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 161/687 (23%), Positives = 231/687 (33%), Gaps = 88/687 (12%)

Query: 213 IFNHKTVVGSKKVNGKIQSTYDQDHTVPAYVPRKLIPITIIKQVIQNVTH-------KDS 265
           + NH T  G  ++ G   +T    +T  A  P    P T       +VT        K  
Sbjct: 152 VINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHF 211

Query: 266 AKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQ---LAKNETLALPAES 322
             S   +       V    PG   TT+    S         KT     A  ET ALP  +
Sbjct: 212 LDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGST 271

Query: 323 KTPEVEKISARPTTV--TPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSK 380
            T     +S + TT   +P +  R+  P  +++  VSE +  S  +P    T    + + 
Sbjct: 272 TT---AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 328

Query: 381 ---VLQPQTATYDVFSSPTTSDEP---------------EISDSYT--------ATSDRI 414
              V Q  TA++ +  S  T+  P                 S  YT         T+  +
Sbjct: 329 MPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGL 388

Query: 415 LDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTS-PEMQPTTPAPQQTTS----IPST 469
           L++  P  S T   P  TL+PS +     +   F S P  + T+PAP  TTS    + +T
Sbjct: 389 LEASTPVHSST-GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTT 447

Query: 470 PKRRPRPKPPRTKPERTTSAG---TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPE 526
               P   P       +T+ G     TP +  SP  T TTP P +    S          
Sbjct: 448 YHSSPSSTPTTHFSASSTTLGHSEESTP-VHSSPVATATTPPPAR----SATSGHVEEST 502

Query: 527 VTHTKPAPKQTPRAPPKPKTSPRPRI------PQTQPVPKVPQRVTAKPKTSPSPEVSYT 580
             H  P   QT   P    TS             T      P    A   TS    +  T
Sbjct: 503 AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGST 562

Query: 581 TPA---PKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQ 637
                     +       + S S P  + T  +P       +PS     +T       + 
Sbjct: 563 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLP----AGSTPSVLVGDSTPSPISSGSM 618

Query: 638 EPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS-VDST 696
           E  TT +P +T     ++    FY++  PR+ D  H+   +  +     +  + S   ST
Sbjct: 619 E--TTALPGSTTKPGLSEKSTTFYSS--PRSPDTTHLPASMTSSGVSEESTTSHSRPGST 674

Query: 697 HPTKKPG-TRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT 755
           H T  PG T  P L    T     P  P + T  PGS    S GP  T    S P  T  
Sbjct: 675 HTTAFPGSTTMPGLSQESTASHSSP-GPTDTTLSPGSTTASSLGPEYT-TFHSRPGST-- 730

Query: 756 PLERIETDIKQPTVPASG--EELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---D 810
                ET +      ASG  E    +   + SP     P G    +G    +   P   D
Sbjct: 731 -----ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKD 785

Query: 811 NSPCSITDSVKRFPKEEATEGNATSPP 837
             P   T +         + G+ +S P
Sbjct: 786 TRPAPPTTTSAFVEPSTTSHGSPSSIP 812



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 121/529 (22%), Positives = 191/529 (36%), Gaps = 66/529 (12%)

Query: 295  PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTT--VTPETVPRSTKP--TT 350
            PAS    +   L T     E+   P+ S +       AR TT  +  E+ P    P  T 
Sbjct: 2447 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2506

Query: 351  SSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTAT 410
            ++ L  S TT + SEK     T+  S D+ +    T +  V    +TS     S   TA 
Sbjct: 2507 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF 2566

Query: 411  SDRILDSIPPKTSRTLEQPRATLAPSETPFVP----------QKLEIFTSPEMQPTTPAP 460
             D    +  P  SR      ++   ++T  +P          +     +SP    T  +P
Sbjct: 2567 PD---STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2623

Query: 461  QQTTSIP-----STPKRRPRPKPPRTKPERTTSAGTI--TPKISKSPEPTWTTPAPGKTQ 513
              TT++      +T    P        P+ TTS+G +  + ++  S     TT +P  + 
Sbjct: 2624 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 2683

Query: 514  FISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPK 570
               L+ +       P  THT P+P  T  AP +  T+   R P + P    P   T    
Sbjct: 2684 SPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYH-RSPGSTPTTHFPASSTTSGH 2742

Query: 571  TS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 624
            +        SP+ S TTP+        +     S+  P   E   I  +P  + +P   E
Sbjct: 2743 SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE---ITTLPGSTTTPGLSE 2799

Query: 625  LQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQAPHRFYTTVRPRTSDKPHIRPG 677
              TT   + +S   P TT  P +        E   +   P   ++TV P ++  P +   
Sbjct: 2800 ASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL--- 2853

Query: 678  VKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSA-GII 736
                     ++ + +V S+     PG+    + PR T    +   P     +P S    +
Sbjct: 2854 ---------SEESTTVYSS----SPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTL 2900

Query: 737  SSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSS 785
             +   TT  L  T   T  P     T    P    + +  E  T F SS
Sbjct: 2901 FTEDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 2947



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 148/649 (22%), Positives = 226/649 (34%), Gaps = 137/649 (21%)

Query: 290  TTVKLPASL----MFEISDALKTQLAKNETLALPAESKTPEVEK-----ISARPTTVTPE 340
            TT   PAS+    + E S   ++Q     +   PA + TP + +      S+ P +    
Sbjct: 3895 TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETT 3954

Query: 341  TVPRST-------KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVL--QPQTATYDV 391
              PRST       +PTT  +   S  T   +E      T+ ++E+S      P +    +
Sbjct: 3955 VFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDS---TTSGLTEESTAFPGSPASTQTGL 4011

Query: 392  FSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTL----EQPRATLAPSET--------- 438
             ++ TT+D  E S ++ ++S      + P  S T     E   + L+PS T         
Sbjct: 4012 PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 4071

Query: 439  --PFVPQKLEIF-TSPEMQPTTPAPQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAG 490
              P + +K   F TSP     T +P  TTS       ST   +P        P+ TT++G
Sbjct: 4072 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSG 4131

Query: 491  -TITPKISKSPE-PTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTS- 547
             +  P  S S +  T  T +PG T   SL  +        H+ P   +T   P    TS 
Sbjct: 4132 LSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ----STTFHSSPGDTETTLLPDDTITSG 4187

Query: 548  -PRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLE 606
                  P       +   +T    TS   +   TT          + +P  S + P+P  
Sbjct: 4188 LVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTT---------FQSWPSSSDTTPSPPS 4238

Query: 607  TRGIPF--------IPMISPSPSQEELQTTLEETDQSTQ--------------------- 637
            T  +P          P  +P+       TTL  +++ST                      
Sbjct: 4239 TTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSV 4298

Query: 638  ---EPF----------TTKIPRTTELAKTTQAPHRFYTTVR-PRTSDKPHIRPGVKQAPR 683
               EP           TT +P +T  A  ++    FY++ R P T+  P           
Sbjct: 4299 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP----------- 4347

Query: 684  PSGADRNVSVDSTHPTKKPG----------TRRPPLPPRPTHPRRKPLPPNNVTGKPGSA 733
             S     VS +ST    +PG          T  P +    T     P    + T  PGS 
Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP-GSTDTTLSPGST 4406

Query: 734  GIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASG--EELENITDFSSSPTRETD 791
               S GP +T    S+P  T       ET +      ASG  E    +   + SP     
Sbjct: 4407 TASSLGPEST-TFHSSPGST-------ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS 4458

Query: 792  PLGKPRFKGPHVRYIQKP---DNSPCSITDSVKRFPKEEATEGNATSPP 837
            P G    +G    +   P   D +P   T +         + G+ +S P
Sbjct: 4459 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTP 4507



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 115/556 (20%), Positives = 187/556 (33%), Gaps = 73/556 (13%)

Query: 285  PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344
            P      V+ P S          T    + T +  +E  T       A  T V P     
Sbjct: 1955 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 2014

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404
            S     S+   +S  ++ ++  P    T  +SE S        +     SP ++    +S
Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 2074

Query: 405  DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVP------- 442
            +  T +  R      P ++ T   P +T  P               ++T  +P       
Sbjct: 2075 EESTTSHSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2128

Query: 443  ---QKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAGTI-- 492
               +     +SP    T  +P  TT++      +T    P        P+ TTS+G +  
Sbjct: 2129 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2188

Query: 493  TPKISKSPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSPR 549
            + ++  S     TT +P  +    L+ +       P  THT P+P  T  AP +  T+  
Sbjct: 2189 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 2248

Query: 550  PRIPQTQPVPKVPQRVTAKPKTS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPA 603
             R P + P    P   T    +        SP+ S TTP+        +     S+  P 
Sbjct: 2249 -RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2307

Query: 604  PLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQA 656
              E   I  +P  + +P   E  TT   + +S   P TT  P +        E   +   
Sbjct: 2308 STE---ITTLPGSTTTPGLSEASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRSQ 2361

Query: 657  PHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHP 716
            P   ++TV P ++      PG+ +      +    S ++T   + P T      P   H 
Sbjct: 2362 PGSTHSTVSPAST----TTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHS 2417

Query: 717  RRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDI--KQPTVPASGE 774
            R         T    ++G+      T  P       TG P      D+  +  T P+S  
Sbjct: 2418 RPASTHTTLFTEDSTTSGLTEES--TAFPGSPASTQTGLPATLTTADLGEESTTFPSS-- 2473

Query: 775  ELENITDFSSSPTRET 790
                 T  + SP R T
Sbjct: 2474 --SGSTGTTLSPARST 2487



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 128/562 (22%), Positives = 193/562 (34%), Gaps = 78/562 (13%)

Query: 285  PGLNETTV---KLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPET 341
            PG   TT+      +S + E S  + +      T   PA S +P ++  S    T    T
Sbjct: 1085 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 1144

Query: 342  VPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEP 401
                + P+T++A     TT   S  P   PT      S        +    SSP  S   
Sbjct: 1145 HTTPSPPSTATAPVEESTTYHRS--PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 1202

Query: 402  EISDSYTATSDR---ILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTP 458
              S +++ TS R       I P ++     P +T  P  +         ++SP    TT 
Sbjct: 1203 P-SSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE---ASTTFYSSPRSPTTTL 1258

Query: 459  APQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLK 518
            +P   TS+    +       P +     + A T TP +S+     +++ + G T+     
Sbjct: 1259 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS-SRGSTETTVFP 1317

Query: 519  PKIPLS-----PEVTHTKPAPKQT---------------PRAPPKPKTSPRPRIPQTQPV 558
                 S     P   H++PA   T                 A P    S +  +P T   
Sbjct: 1318 HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 1377

Query: 559  PKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISP 618
              + +  T  P +S S     +        L  +  P  S+  P+  ET  +P  P    
Sbjct: 1378 ADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP--SRLSPSSTETTTLPGSP---T 1432

Query: 619  SPSQEELQTTLEETDQS---TQEPFTTKIPRTTELAKTTQA-PHRFYTTVRP---RTSD- 670
            +PS  E  TT   + +S   T  P TT     +E + T+ + P   +TT  P    TSD 
Sbjct: 1433 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDL 1492

Query: 671  -----KPHIRPGVKQAPRPSGADRNVSV--DSTHPTKKPGTRRPPLPP------------ 711
                   H   G  +A    G+    S+   ST     PG     L P            
Sbjct: 1493 SQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 1552

Query: 712  RPTHPRRKPLPPNNVTGKPGSAGI------ISSGPITTPPLRSTPRPTGTPLERIETDIK 765
             PTH     L          SAG+        S P ++    +TP P GT    +E    
Sbjct: 1553 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD---TTPSPPGTTAAPVEVSTT 1609

Query: 766  QPTVPASGEELENITDFSSSPT 787
              + P+S       T FS+S T
Sbjct: 1610 YHSRPSS----TPTTHFSASST 1627



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/550 (20%), Positives = 186/550 (33%), Gaps = 80/550 (14%)

Query: 285  PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344
            P      V+ P S          T    + T +  +E  T       A  T V P     
Sbjct: 3512 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 3571

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404
            S     S+   +S  ++ ++  P    T  +SE S        +     SP ++    +S
Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 3631

Query: 405  DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVP------- 442
            +  T +  R      P ++ T   P +T  P               ++T  +P       
Sbjct: 3632 EESTTSHSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 3685

Query: 443  ---QKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAGTI-- 492
               +     +S     T  +P  TT++      +T    P        P+ TTS+G +  
Sbjct: 3686 SSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 3745

Query: 493  TPKISKSPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSPR 549
            + ++  S     TT +P  +    L+ +       P  THT P+P  T  AP +  T+  
Sbjct: 3746 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 3805

Query: 550  PRIPQTQPVPKVPQRVTAKPKTS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPA 603
             R P + P    P   T    +        SP+ S TTP+        +     S+  P 
Sbjct: 3806 -RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 3864

Query: 604  PLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQA 656
              E   I  +P  + +P   E  TT   + +S   P TT  P +        E   +   
Sbjct: 3865 STE---ITTLPGSTTTPGLSEASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRSQ 3918

Query: 657  PHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHP 716
            P   ++TV P ++  P +            ++ + +V S+     PG+    + PR T  
Sbjct: 3919 PGSTHSTVSPASTTTPGL------------SEESTTVYSS----SPGSTETTVFPRSTTT 3962

Query: 717  RRKPLPPNNVTGKPGSA-GIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEE 775
              +   P     +P S    + +   TT  L  T   T  P     T    P    + + 
Sbjct: 3963 SVRREEPTTFHSRPASTHTTLFTEDSTTSGL--TEESTAFPGSPASTQTGLPATLTTADL 4020

Query: 776  LENITDFSSS 785
             E  T F SS
Sbjct: 4021 GEESTTFPSS 4030



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 123/560 (21%), Positives = 186/560 (33%), Gaps = 73/560 (13%)

Query: 295  PASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTT--VTPETVPRSTKPTTSS 352
            PAS    +   L T     E+   P+ S +       AR TT  +  E+ P    P+++ 
Sbjct: 2921 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2980

Query: 353  ALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSD 412
                  TTL  S       T  +SE S        + D   SP T+    +S+  + +  
Sbjct: 2981 T-----TTLPGSPT-----TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 3030

Query: 413  RILDSIPPKTSRTLEQPRATLA------PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI 466
            +      P ++ T   P +T        P+ +       E   SP     +   QQ+T+ 
Sbjct: 3031 Q------PGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084

Query: 467  PSTP-KRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSP 525
             S+P        P  T       A T T   + S   T T  +                P
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 3144

Query: 526  EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 585
              + T P+P  T  AP +  T+   R P + P        T   ++  S  V  +  A  
Sbjct: 3145 SSSDTTPSPPGTTAAPVEVSTTYHSR-PSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 3203

Query: 586  DVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645
              L P +    V   EP                        TT   +  ST+   TT +P
Sbjct: 3204 TALFPTRSATSVLVGEP------------------------TTSPISSGSTE---TTALP 3236

Query: 646  RTTELAKTTQAPHRFYTTVR-PRTSDKP--HIRPGVKQAPRPSGADRNVSVDSTHPTKKP 702
             +T  A  ++    FY++ R P T+  P      GV +    S    +    STH T  P
Sbjct: 3237 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS----HSRPGSTHTTAFP 3292

Query: 703  GTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIET 762
            G+   P   + +          + T  PGS    S GP +T    S P  T       ET
Sbjct: 3293 GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPEST-TFHSGPGST-------ET 3344

Query: 763  DIKQPTVPASG--EELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---DNSPCSIT 817
             +      ASG  E    +   + SP     P G    +G    +   P   D +P   T
Sbjct: 3345 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPT 3404

Query: 818  DSVKRFPKEEATEGNATSPP 837
             +         + G+ +S P
Sbjct: 3405 TTSAFVELSTTSHGSPSSTP 3424



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 91/437 (20%), Positives = 150/437 (34%), Gaps = 63/437 (14%)

Query: 285  PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344
            P      V+ P S          T    + T +  +E  T       A  T V P     
Sbjct: 872  PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 931

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404
            S     S+   +S  ++ ++  P    T  +SE S        +     SP ++    +S
Sbjct: 932  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 991

Query: 405  DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVPQKLEIFT 449
            +  T +  R      P ++ T   P +T  P               ++T  +P      +
Sbjct: 992  EESTTSRSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT-S 1044

Query: 450  SPEMQPTTP-----------APQQTTSI-----PSTPKRRPRPKPPRTKPERTTSAGTI- 492
             P  + TT            +P  TT++      +T    P        P+ TTS+G + 
Sbjct: 1045 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE 1104

Query: 493  -TPKISKSPEPTWTTPAPGKTQFISLKPK---IPLSPEVTHTKPAPKQTPRAPPKPKTSP 548
             + ++  S     TT +P  +    L+ +       P  THT P+P  T  AP +  T+ 
Sbjct: 1105 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 1164

Query: 549  RPRIPQTQPVPKVPQRVTAKPKTS------PSPEVSYTTPAPKDVLLPHKPYPEVSQSEP 602
              R P + P    P   T    +        SP+ S TTP+        +     S+  P
Sbjct: 1165 H-RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 1223

Query: 603  APLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRT-------TELAKTTQ 655
               E   I  +P  + +P   E  TT   + +S   P TT  P +        E   +  
Sbjct: 1224 GSTE---ITTLPGSTTTPGLSEASTTFYSSPRS---PTTTLSPASMTSLGVGEESTTSRS 1277

Query: 656  APHRFYTTVRPRTSDKP 672
             P   ++TV P ++  P
Sbjct: 1278 QPGSTHSTVSPASTTTP 1294



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 126/536 (23%), Positives = 192/536 (35%), Gaps = 72/536 (13%)

Query: 268  SPEKAPLGGVI---LVHLIIPGLNETTVKLPAS----LMFEISDALKTQLAKNETLALPA 320
            SP ++   G++       + P   ETT  LP S     + E S    T     +    PA
Sbjct: 4039 SPARSTTSGLVGESTPSRLSPSSTETTT-LPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097

Query: 321  ESKTPEVEKISARPTTVTPETVPRSTKPT------TSSALDVSETTLASSEKPWIVPTAK 374
             + +  V + S+     T  + P ST  T      T+S L    TT  SS+       + 
Sbjct: 4098 TTTSSGVSEESS-----TSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP 4152

Query: 375  ISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434
             S  +  L  Q+ T+   SSP  ++   + D  T TS  +  S P  +S        T A
Sbjct: 4153 GSTTASSLGQQSTTFH--SSPGDTETTLLPDD-TITSGLVEASTPTHSSTGSLHTTLTPA 4209

Query: 435  PSETPFVPQKLEIFTS-PEMQPTTPAPQQTTSIP----STPKRRPRPKPPRTKPERTTSA 489
             S +  + ++   F S P    TTP+P  TT++P    +T   RP   P       +T+ 
Sbjct: 4210 SSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269

Query: 490  GTI--TPKISKSPEPTWTT--PAPGKTQFISLKPKI-PLSPEVTHTKPAPKQTPRAPPKP 544
            G    +  +  SP  T T   P    T  +  +P   P+S   T T   P  T  A    
Sbjct: 4270 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 4329

Query: 545  KTS---PRPRIPQT--QPVPKVPQRVTAKPKTSPS-PEVSYTTPAPKDVLLPH-KPYPEV 597
            K++     PR P T   P       V+ +  TS S P   +TT  P    +P        
Sbjct: 4330 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTA 4389

Query: 598  SQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAP 657
            S S P   +T      P  + + S     TT   +  ST+   TT +P  T  +   +A 
Sbjct: 4390 SHSSPGSTDT---TLSPGSTTASSLGPESTTFHSSPGSTE---TTLLPDNTTASGLLEA- 4442

Query: 658  HRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPT--- 714
                +T    ++  PH          P+G+       +T  +        P PP  T   
Sbjct: 4443 ----STPVHSSTGSPH------TTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492

Query: 715  -------HPRRKPLPPNNVT------GKPGSAGIISSGPITTPPLRSTPRPTGTPL 757
                   H      P  + +      G+   +  + S P+ T    S  R T + L
Sbjct: 4493 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 4548



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 131/563 (23%), Positives = 191/563 (33%), Gaps = 87/563 (15%)

Query: 339  PETVPRSTKPTTSSALDVSETTLASSEK----------------PWIVPTAKISEDSKVL 382
            P T P S+  T ++AL  S TT   SEK                P    ++ +SE+S   
Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 4362

Query: 383  QPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVP 442
              +  +    + P+++  P +S   TA+      S P  T  TL  P +T A S     P
Sbjct: 4363 HSRPGSMHTTAFPSSTTMPGVSQESTAS-----HSSPGSTDTTL-SPGSTTASS---LGP 4413

Query: 443  QKLEIFTSPEMQPTTPAPQQTTSI----PSTPKRRPRPKPPRT-KPERTTSAGTITPKIS 497
            +     +SP    TT  P  TT+      STP       P  T  P  +T+    +    
Sbjct: 4414 ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 4473

Query: 498  KSPEPTWTTPAPGKT--QFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQT 555
              P    TTPAP  T   F+ L          T +  +P  TP       ++   R  ++
Sbjct: 4474 SWPNSKDTTPAPPTTTSAFVELS---------TTSHGSPSSTPTTHFSASSTTLGRSEES 4524

Query: 556  QPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH-KPYPEVSQSEPAPLETRGIPFIP 614
              V   P        T+PSP  S T+   ++    H  P    +   P    T G     
Sbjct: 4525 TTVHSSP----VATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEES 4580

Query: 615  MISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHI 674
              S S +   + +    T    +EP  T    +     TT  P    T+ R   S   H 
Sbjct: 4581 TTSHSSTTHTISSAPSTTSALVEEP--TSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 4638

Query: 675  ---RPGVKQAPRPSGADRNVSVDSTHP--------TKKPG-TRRPPLPPRPT--HPRRKP 720
                 G    P  S     +   +T P        T  PG T  P L  + T  H     
Sbjct: 4639 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSS 4698

Query: 721  LPPNNVT------GKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQ-------- 766
             P  + +      G+   +  + S P+ T    S  R T + L    T            
Sbjct: 4699 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 4758

Query: 767  ---PTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRF 823
                +  ASG   E+ T  SS+    + P   P      V       +SP SI  +   F
Sbjct: 4759 HFPESSTASGRSEESRTSHSSTTHTISSP---PSTTSALVEEPTSYHSSPGSI--ATTHF 4813

Query: 824  PKEEATEG---NATSPPQNPPTN 843
            P+   T G    +T+   +P TN
Sbjct: 4814 PESSTTSGRSEESTASHSSPDTN 4836



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 144/680 (21%), Positives = 225/680 (33%), Gaps = 103/680 (15%)

Query: 311  AKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIV 370
            +  ET  LP    TP + + S    T +P +   +  P T+++  VSE +  S  +P   
Sbjct: 1420 SSTETTTLPGSPTTPSLSEKSTTFYT-SPRSPDATLSPATTTSSGVSEESSTSHSQPGST 1478

Query: 371  PTAKISEDSKVLQPQTATYDVFSSPTTSD------------------------------- 399
             T    +        T T D+   PTTS                                
Sbjct: 1479 HTTAFPDS-------TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 1531

Query: 400  ---EPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTS-PEMQP 455
               E  +    T TS  +  S P  +S        T A S +  + ++   F S P    
Sbjct: 1532 GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD 1591

Query: 456  TTPAPQQTTSIP----STPKRRPRPKPPRTKPERTTSAGTI--TPKISKSPEPTWTT--P 507
            TTP+P  TT+ P    +T   RP   P       +T+ G    +  +  SP  T T   P
Sbjct: 1592 TTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 1651

Query: 508  APGKTQFISLKPKI-PLSPEVTHTKPAPKQTPRAPPKPKTS---PRPRIPQT--QPVPKV 561
                T  +  +P   P+S   T T   P  T  A    K++     PR P T   P    
Sbjct: 1652 TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 1711

Query: 562  PQRVTAKPKTSPS-PEVSYTTPAPKDVLLPH-KPYPEVSQSEPAPLETRGIPFIPMISPS 619
               V+ +  TS S P  ++TT  P    +P        S S P   +T      P  + +
Sbjct: 1712 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT---TLSPGSTTA 1768

Query: 620  PSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVK 679
             S     TT   +  ST+   TT +P  T  +   +A     +T    ++  PH      
Sbjct: 1769 SSLGPESTTFHSSPGSTE---TTLLPDNTTASGLLEA-----STPVHSSTGSPH------ 1814

Query: 680  QAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSG 739
                P+G+       +T  +        P PP  T    +    ++  G P S       
Sbjct: 1815 TTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH--GSPSSTPTTHFS 1872

Query: 740  PITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFK 799
              +T   RS    T             P    +   +E  T + SSP             
Sbjct: 1873 ASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP------------- 1919

Query: 800  GPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILD 859
                + +  P++S  S         +E  T  ++T+   + P + T   VE   S+    
Sbjct: 1920 -GSTQTMHFPESSTASGRS------EESRTSHSSTTHTISSPPSTTSALVEEPTSY---- 1968

Query: 860  WEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGE 919
               P +   T +   S  +G       S    + T + V   +  TS        +P+  
Sbjct: 1969 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 2028

Query: 920  GPVSNTVAFSTESADPRVSE 939
            G +  T A    +  P +SE
Sbjct: 2029 GSM-ETTALPGSTTTPGLSE 2047



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 88/402 (21%), Positives = 140/402 (34%), Gaps = 31/402 (7%)

Query: 285  PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344
            PG     V++  +     S    T  + + T    +E  T       A  T + P     
Sbjct: 1597 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT 1656

Query: 345  ST---KPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEP 401
            S    +PTTS    +S  +  ++  P    TA +SE S        + D   SP ++   
Sbjct: 1657 SVLVGEPTTSP---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 1713

Query: 402  EISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQ 461
             +S+  T +  R      P ++ T   P +T  P  +    +     +SP    TT +P 
Sbjct: 1714 GVSEESTTSHSR------PGSTHTTAFPGSTTMPGVS---QESTASHSSPGSTDTTLSPG 1764

Query: 462  QTTSIPSTPKRRPRPKPPRTK-----PERTTSAGTI---TPKISKSPEPTWTTPAPGKTQ 513
             TT+    P+       P +      P+ TT++G +   TP  S +  P  T    G T 
Sbjct: 1765 STTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 1824

Query: 514  FISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTS- 572
                       P    T PAP  T  A  +  T+     P + P        T   ++  
Sbjct: 1825 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS-PSSTPTTHFSASSTTLGRSEE 1883

Query: 573  -----PSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQT 627
                  SP  + TTP+P           E +    +P  T+ + F    + S   EE +T
Sbjct: 1884 STTVHSSPVATATTPSPARSTTSGL-VEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942

Query: 628  TLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTS 669
            +   T  +   P +T      E      +P    TT  P +S
Sbjct: 1943 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSS 1984



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 113/500 (22%), Positives = 170/500 (34%), Gaps = 39/500 (7%)

Query: 301 EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSE-- 358
           E S A        +T+  P  S T    + SA     T  T  +S+ P+T++AL  +   
Sbjct: 499 EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT--KSSTPSTTAALAHTSYH 556

Query: 359 TTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSI 418
           ++L S+E      ++ IS  S+  +   ++ D  +   T+  P  S       D     I
Sbjct: 557 SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA---TTVLPAGSTPSVLVGDSTPSPI 613

Query: 419 PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRR 473
              +  T   P +T  P  +    +    ++SP    TT  P   TS       +T   R
Sbjct: 614 SSGSMETTALPGSTTKPGLSE---KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 670

Query: 474 PRPKPPRTKPERTTSAGTITPKISK--SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTK 531
           P        P  TT  G      +   SP PT TT +PG T   SL P+        H++
Sbjct: 671 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY----TTFHSR 726

Query: 532 PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH 591
           P   +T   P    T+    +  + PV       T  P T+ SP  S T           
Sbjct: 727 PGSTETTLLP--DNTTASGLLEASMPV----HSSTRSPHTTLSPAGSTTRQGESTTF--- 777

Query: 592 KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT---LEETDQSTQEPFTT--KIPR 646
             +P    + PAP  T      P  +   S   + TT      T     E  TT    P 
Sbjct: 778 HSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG 837

Query: 647 TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706
           +T+   T   P    T+ R   S   H       +  PS     V   +++ +    T  
Sbjct: 838 STQ---TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 894

Query: 707 PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQ 766
              P   T   R      + + +  +  I+     TT  L      +      +ET    
Sbjct: 895 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 954

Query: 767 PTVPASGEELENITDFSSSP 786
            +    G   E  T F SSP
Sbjct: 955 GSTTTPGLS-ERSTTFHSSP 973



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 106/485 (21%), Positives = 162/485 (33%), Gaps = 35/485 (7%)

Query: 339  PETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTS 398
            P T P S+  T ++AL  S TT   SEK     ++  S D+ +    T +  V    TTS
Sbjct: 3220 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 3279

Query: 399  DEPEISDSYTA-TSDRILDSIPPKTSRTLEQPRA---TLAPSET---PFVPQKLEIFTSP 451
                 S   TA      +  +  +++ +   P +   TL+P  T      P+     + P
Sbjct: 3280 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGP 3339

Query: 452  EMQPTTPAPQQTTSI----PSTPKRRPRPKPPRT-KPERTTSAGTITPKISKSPEPTWTT 506
                TT  P  TT+      STP       P  T  P  +T+    +      P    TT
Sbjct: 3340 GSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTT 3399

Query: 507  PAPGKT--QFISLKPK---IPLSPEVTHTKPAPKQTPR---------APPKPKTSPRPRI 552
            PAP  T   F+ L       P S   TH   +     R         +P    T+P P  
Sbjct: 3400 PAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR 3459

Query: 553  PQTQPVPKVPQRVTAKP---KTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRG 609
              T  + +      + P   +T   PE   T+   ++    H        S  AP  T  
Sbjct: 3460 STTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS--APSTTSA 3517

Query: 610  IPFIP-MISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRT 668
            +   P     SP         + +  S +   +T    + +   T   P R  T+V    
Sbjct: 3518 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 3577

Query: 669  SDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT- 727
            S    I  G  +     G+     +     T     R P     P       +   + T 
Sbjct: 3578 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 3637

Query: 728  -GKPGSAGIIS-SGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSS 785
              +PGS    +     TTP L      + +     +T +   +   SG   E+ T  SSS
Sbjct: 3638 HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSS 3697

Query: 786  PTRET 790
             + +T
Sbjct: 3698 GSTDT 3702



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 102/462 (22%), Positives = 156/462 (33%), Gaps = 99/462 (21%)

Query: 282  LIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKIS--------AR 333
            +++P  + T+V L  S    IS          ET ALP  + TP + + S        + 
Sbjct: 4646 IVLPARSTTSVLLGESTTSPISSG------SMETTALPGSTTTPGLSEKSTTFHSSPSST 4699

Query: 334  PTT----------------------VTPETVPRSTKPTTSSALDVSETTLAS--SEKPWI 369
            PTT                      V   T P   + TTS  ++ S    +S  S +   
Sbjct: 4700 PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 4759

Query: 370  VPTAKI----SEDSKVLQPQTATYDVFSSP-TTSDEPEISDSYTATSDRILDSIPPKTSR 424
             P +      SE+S+     T T+ + S P TTS   E   SY ++   I  +  P++S 
Sbjct: 4760 FPESSTASGRSEESRTSHSST-THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESST 4818

Query: 425  TLEQPRATLAPSETP----------------FVPQKLEIFTSPEMQPTTPAPQQTTSIPS 468
            T  +   + A   +P                 + +    + SP    TT A   TT  P 
Sbjct: 4819 TSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT--PG 4876

Query: 469  TPKRRPRPKPPRTKPERTTSAGTIT-PKISKSP-------EPTWTTPAPGKTQFISLKPK 520
               +          P++T S  ++T   IS  P       E T TT  P  T    L  +
Sbjct: 4877 LSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQE 4936

Query: 521  IPLSPEVTHTKPAPKQTPRAPPKPKTSPRPR---IPQTQP---VPKVPQRVTAKPKTSPS 574
                    H+KP   +T  +P    TS   +    P +QP   +  V    T  P  S  
Sbjct: 4937 ----STTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992

Query: 575  PEVSYTTP-APKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETD 633
                Y++P + +     H     +   +  P            SP  +   L  TL  TD
Sbjct: 4993 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPD---------SPGFTHTVLPATLTTTD 5043

Query: 634  ---------QSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666
                      S+    TT +P  +  +     P  FY +  P
Sbjct: 5044 IGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSP 5085


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 160/687 (23%), Positives = 231/687 (33%), Gaps = 88/687 (12%)

Query: 213 IFNHKTVVGSKKVNGKIQSTYDQDHTVPAYVPRKLIPITIIKQVIQNVTH-------KDS 265
           + NH T  G  ++ G   +T    +T  A  P    P T       +VT        K  
Sbjct: 73  VINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHF 132

Query: 266 AKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQ---LAKNETLALPAES 322
             S   +       V    PG   TT+    S         KT     A  ET ALP  +
Sbjct: 133 LDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGST 192

Query: 323 KTPEVEKISARPTTV--TPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTAKISEDSK 380
            T     +S + TT   +P +  R+  P  +++  VSE +  S  +P    T    + + 
Sbjct: 193 TT---AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTT 249

Query: 381 ---VLQPQTATYDVFSSPTTSDEP---------------EISDSYT--------ATSDRI 414
              V Q  TA++ +  S  T+  P                 S  YT         T+  +
Sbjct: 250 MPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGL 309

Query: 415 LDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTS-PEMQPTTPAPQQTTS----IPST 469
           L++  P  S T   P  TL+P+ +     +   F S P  + T+PAP  TTS    + +T
Sbjct: 310 LEASTPVHSST-GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTT 368

Query: 470 PKRRPRPKPPRTKPERTTSAG---TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPE 526
               P   P       +T+ G     TP +  SP  T TTP P +    S          
Sbjct: 369 YHSSPSSTPTTHFSASSTTLGHSEESTP-VHSSPVATATTPPPAR----SATSGHVEEST 423

Query: 527 VTHTKPAPKQTPRAPPKPKTSPRPRI------PQTQPVPKVPQRVTAKPKTSPSPEVSYT 580
             H  P   QT   P    TS             T      P    A   TS    +  T
Sbjct: 424 AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGST 483

Query: 581 TPA---PKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQ 637
                     +       + S S P  + T  +P       +PS     +T       + 
Sbjct: 484 ETTHFRDSSTISGRSEESKASHSSPDAMATTVLP----AGSTPSVLVGDSTPSPISSGSM 539

Query: 638 EPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVS-VDST 696
           E  TT +P +T     ++    FY++  PR+ D  H+   +  +     +  + S   ST
Sbjct: 540 E--TTALPGSTTKPGLSEKSTTFYSS--PRSPDTTHLPASMTSSGVSEESTTSHSRPGST 595

Query: 697 HPTKKPG-TRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGT 755
           H T  PG T  P L    T     P  P + T  PGS    S GP  T    S P  T  
Sbjct: 596 HTTAFPGSTTMPGLSQESTASHSSP-GPTDTTLSPGSTTASSLGPEYT-TFHSRPGST-- 651

Query: 756 PLERIETDIKQPTVPASG--EELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKP---D 810
                ET +      ASG  E    +   + SP     P G    +G    +   P   D
Sbjct: 652 -----ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSND 706

Query: 811 NSPCSITDSVKRFPKEEATEGNATSPP 837
             P   T +         + G+ +S P
Sbjct: 707 TRPAPPTTTSAFVEPSTTSHGSPSSIP 733



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 101/494 (20%), Positives = 161/494 (32%), Gaps = 65/494 (13%)

Query: 285  PGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPR 344
            P      V+ P S          T    + T +  +E          A  T V P     
Sbjct: 793  PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTN 852

Query: 345  STKPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEIS 404
            S     S+   +S  ++ ++  P    T  +SE S        +     SP ++    +S
Sbjct: 853  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 912

Query: 405  DSYTATSDRILDSIPPKTSRTLEQPRATLAP---------------SETPFVPQK--LEI 447
            +  T +  R      P ++ T   P +T  P               ++T  +P      +
Sbjct: 913  EESTTSHSR------PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXL 966

Query: 448  FTSPEMQPTTPAPQQTTSIP------------STPKRRPRPKPPRTKPERTTSAGTITPK 495
               P   P +    +TT++P            +T    PR       P  TTS+G     
Sbjct: 967  VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1026

Query: 496  ISKSPEP--TWTTPAPGKTQFISLKPKIPL---SPEVTHTKPAPKQTPRAPPKPKTSPRP 550
             +    P  T TT  PG T    +  +      SP  T T  +P+ T  +   P+++   
Sbjct: 1027 TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFH 1086

Query: 551  RIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLP------------HKPYPEVS 598
              P +     +P   TA      S  V  +T +P+  L P             + +P   
Sbjct: 1087 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSK 1146

Query: 599  QSEPAPLETRGIPFIPMISPS-PSQEELQTTLEETDQST--QEPFTTKIPRTTELAKTTQ 655
             + PAP  T    F+ + + S  S   + TT      +T  +   +T +  +     TT 
Sbjct: 1147 DTMPAPPTTTS-AFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTP 1205

Query: 656  APHRFYTTVRPRTSDKPHIRPGVKQA---PRPSGA------DRNVSVDSTHPTKKPGTRR 706
            +P R  T+     S   H  PG  Q    P  S A       R     +TH    P +  
Sbjct: 1206 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 1265

Query: 707  PPLPPRPTHPRRKP 720
              L   PT     P
Sbjct: 1266 SALVEEPTSYHSSP 1279



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 120/510 (23%), Positives = 176/510 (34%), Gaps = 96/510 (18%)

Query: 314  ETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEK------- 366
            +T  LPA + T  V +         P T P S+  T ++AL  S TT   SEK       
Sbjct: 954  DTTLLPASTTTXLVGE---------PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1004

Query: 367  ---------PWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDS 417
                     P    ++ +SE+S     +  +    + P ++  P +S   TA+      S
Sbjct: 1005 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTAS-----HS 1059

Query: 418  IPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI----PSTPKRR 473
             P  T  TL  PR+T A S     P+     + P    TT  P  TT+      STP   
Sbjct: 1060 SPGSTDTTL-SPRSTTASS---LGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 1115

Query: 474  PRPKPPRT-KPERTTSAGTITPKISKSPEPTWTTPAPGKT--QFISLKPKIPLSPEVTHT 530
                P  T  P  +T+    +      P    T PAP  T   F+ L          T +
Sbjct: 1116 STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS---------TTS 1166

Query: 531  KPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLP 590
              +P   P       ++   R  ++  V   P      P T+PSP  S T+   ++    
Sbjct: 1167 HGSPSSIPTTHFSASSTTFGRSEESTTVHSSP----VAPATTPSPARSTTSGLVEESTAY 1222

Query: 591  HKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTEL 650
            H           +P  T+ + F    + S   EE +T+   T  +   P +T      E 
Sbjct: 1223 HS----------SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP 1272

Query: 651  AKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP 710
                 +P    TT  P +S               SG     S +ST     P T    + 
Sbjct: 1273 TSYHSSPGSIATTHFPESS-------------TTSGR----SEESTASHSSPDTN--GIT 1313

Query: 711  PRPTHPRRKPLPPNNVTG--KPGSAGIISSGPITTPPLRS----------TPRPTGTPLE 758
            P P H         + T    PGS     +   TTP L +          +P  T +P  
Sbjct: 1314 PLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPAS 1373

Query: 759  RIETDIK-QPTVPASGEELENITDFSSSPT 787
               + I  +PT   S  E  + T F +S T
Sbjct: 1374 MTSSSISGEPTSLYSQAESTHTTAFPASTT 1403



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 141/667 (21%), Positives = 220/667 (32%), Gaps = 46/667 (6%)

Query: 301  EISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSE-- 358
            E S A        +T+  P  S T    + SA     T  T  +S+ P+T++AL  +   
Sbjct: 420  EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT--KSSTPSTTAALAHTSYH 477

Query: 359  TTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSI 418
            ++L S+E      ++ IS  S+  +   ++ D  +   T+  P  S       D     I
Sbjct: 478  SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMA---TTVLPAGSTPSVLVGDSTPSPI 534

Query: 419  PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSI-----PSTPKRR 473
               +  T   P +T  P  +    +    ++SP    TT  P   TS       +T   R
Sbjct: 535  SSGSMETTALPGSTTKPGLSE---KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 591

Query: 474  PRPKPPRTKPERTTSAGTITPKISK--SPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTK 531
            P        P  TT  G      +   SP PT TT +PG T   SL P+        H++
Sbjct: 592  PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY----TTFHSR 647

Query: 532  PAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPH 591
            P   +T   P    T+    +  + PV       T  P T+ SP  S T           
Sbjct: 648  PGSTETTLLP--DNTTASGLLEASMPV----HSSTRSPHTTLSPAGSTTRQGESTTF--- 698

Query: 592  KPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTT---LEETDQSTQEPFTT--KIPR 646
              +P  + + PAP  T      P  +   S   + TT      T     E  TT    P 
Sbjct: 699  HSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPG 758

Query: 647  TTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRR 706
            +T+   T   P    T+ R   S   H       +  PS     V   +++ +    T  
Sbjct: 759  STQ---TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTAT 815

Query: 707  PPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQ 766
               P   T   R      + + +  +  I+     T   L      +      +ET    
Sbjct: 816  THFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALP 875

Query: 767  PTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKE 826
             +    G   E  T F SSP      L         V       +S    T +   FP  
Sbjct: 876  GSTTTPGLS-ERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTT-AFPDS 933

Query: 827  EATEG----NATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFS 882
              T G    + TS      T+ T++        V      P++   TE   +     +  
Sbjct: 934  TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAG 993

Query: 883  GKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEG--PVSNTVAFSTESADPRVSEP 940
               KS    +   S    L P ++    V  ++         ++T AF   +  P VS+ 
Sbjct: 994  LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQE 1053

Query: 941  VSAGRDA 947
             +A   +
Sbjct: 1054 STASHSS 1060



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 86/386 (22%), Positives = 133/386 (34%), Gaps = 63/386 (16%)

Query: 328  EKISARPTTVTPETVPRSTKPTTSSALDVSETTLAS--SEKPWIVPTAKI----SEDSKV 381
            E  +   + V P T P   + TTS  ++ S    +S  S +    P +      SE+S+ 
Sbjct: 1190 ESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1249

Query: 382  LQPQTATYDVFSSP-TTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETP- 439
                T T+ + S P TTS   E   SY ++   I  +  P++S T  +   + A   +P 
Sbjct: 1250 SHSST-THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPD 1308

Query: 440  ---------------FVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE 484
                            + +    + SP    TT A   TT  P    +          P+
Sbjct: 1309 TNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT--PGLSAKSTILYSSSRSPD 1366

Query: 485  RTTSAGTIT-PKISKSP-------EPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQ 536
            +T S  ++T   IS  P       E T TT  P  T    L  +        H+KP   +
Sbjct: 1367 QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQE----STTFHSKPGSTE 1422

Query: 537  TPRAPPKPKTSPRPR---IPQTQP---VPKVPQRVTAKPKTSPSPEVSYTTP-APKDVLL 589
            T  +P    TS   +    P +QP   +  V    T  P  S      Y++P + +    
Sbjct: 1423 TTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAF 1482

Query: 590  PHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETD---------QSTQEPF 640
             H     +   +  P            SP  +   L  TL  TD          S+    
Sbjct: 1483 SHSNTMSIHSQQSTPFPD---------SPGFTHTVLPATLTTTDIGQESTAFHSSSDATG 1533

Query: 641  TTKIPRTTELAKTTQAPHRFYTTVRP 666
            TT +P  +  +     P  FY +  P
Sbjct: 1534 TTPLPARSTASDLVGEPTTFYISPSP 1559


>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
          Length = 669

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 136/594 (22%), Positives = 215/594 (36%), Gaps = 118/594 (19%)

Query: 307 KTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEK 366
           K Q ++ E   LP +   PE  K+         E   ++  P             A S K
Sbjct: 21  KFQASQPEPSDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFG----------AVSLK 70

Query: 367 PWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRT- 425
           P   P  ++++  K   P   T      P     PE++D         +  +P K S+  
Sbjct: 71  P---PPPEVTDLPKKPPPPEVT----DLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLE 123

Query: 426 ---LEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTK 482
              L +    L  +  P  P + E+  +P ++ + P P      P  P     P  P ++
Sbjct: 124 LSDLSKKFPQLGATPFPRKPLQPEVGEAP-LKASLPEPGAPARKPLQPDELSHPARPPSE 182

Query: 483 PERTT--------SAGTITPKISKSPEPTWTT--PAPGKTQFISLKPKIPLSPEVTHTKP 532
           P+            AG  TP+   SP+P  +T    P + +F ++ PK P  P+V     
Sbjct: 183 PKSGAFPRKLWQPEAGEATPR---SPQPELSTFPKKPAQPEF-NVYPKKPPQPQVGGL-- 236

Query: 533 APKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR-VTAKPKTSPSPEVSYTTPAPKDVLL-- 589
            PK   ++ P+P+ S   + P  +P    P+R  +A PK +  P +S     P    L  
Sbjct: 237 -PK---KSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKKPPQPELGD 292

Query: 590 ----PHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 645
                 +P   V    P P E + +      S  P Q EL        +++ EP    +P
Sbjct: 293 LTRTSSEPEVSVLPKRPRPAEFKAL------SKKPPQPELGGL----PRTSSEPEFNSLP 342

Query: 646 RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGV-----KQAPRPSGADRN------VSVD 694
           R   L    + P R ++   P    K H +P       ++ P PS A  +          
Sbjct: 343 RKL-LQPERRGPPRKFSQPEPSAVLKRHPQPEFFGDLPRKPPLPSSASESSLPAAVAGFS 401

Query: 695 STHPTKK-----------------PGTRRPPLPPRPTHP-RRKPLPPNNVTGKPGSAGII 736
           S HP                     G  RP L  RP+HP RR+PLPP +  G P +   +
Sbjct: 402 SRHPLSPGFGAAGTPRWRSGGLVHSGGARPGL--RPSHPPRRRPLPPASSLGHPPAKPPL 459

Query: 737 SSGPITTPPLRSTPRPTGTPLERIET---------DIKQPTVPASGEELENITDFSSSPT 787
             GP+    ++S  RP+   ++   T         D +   +P   E  E   D    P 
Sbjct: 460 PPGPV---DMQSFRRPSAASIDLRRTRSAAGLHFQDRQPEDIPVPDEIYELYDDV--EPR 514

Query: 788 RETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPP 841
            ++ P  K R + P             S+  + +R P++ A        PQ  P
Sbjct: 515 DDSSPSPKGRDEAP-------------SVQQAARRPPQDPALRKEKDPQPQQLP 555


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 114/487 (23%), Positives = 172/487 (35%), Gaps = 80/487 (16%)

Query: 309 QLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPW 368
           +++  ET+A    ++ P+   +SA     T    P +  P  +     + T +     P 
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL---PR 182

Query: 369 IVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQ 428
             P+A+         P+  T     S +++ E   ++   A   R      P     L++
Sbjct: 183 PAPSAR---------PRPPTEGPRKSVSSASEHSTTEPSPAARRR------PSAGGGLQR 227

Query: 429 PRA-TLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPK------PPRT 481
           P + +L+ S TP         +SP    + P+ + T   P+ P + P+PK      PP+ 
Sbjct: 228 PASRSLSSSATPL--------SSPAR--SGPSARGTPRAPAHPSQ-PKPKGLQALRPPQV 276

Query: 482 KPERTTSAGTITPKISK---SPEPTWTTPAPGKTQFISLKPKIPLSP------------- 525
            P R  +A  + P  S    +P P+   P+P     +   P  P +P             
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPS-APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335

Query: 526 EVTHT-KPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSP--------- 575
           + TH+  P+P  +P A P P+  P   +P  Q  P  P      P  +PSP         
Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395

Query: 576 --EVSYTTPAPKDVLLPHKP--YPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631
             +  ++ P    V  P  P   P VS S   P +       P +   PS          
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 632 TDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691
                Q P     P         QAP    T         P   PG  QAP    A   +
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG--QAPFSPSASLPM 513

Query: 692 SVDSTHPTKKPGTRRPPL---PPRP------THPRRKPLP-PNNVTGKPGSAGIISSGPI 741
           S  +T P + P     PL   PP P        PRR P P P+     P     ++ GP 
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP- 572

Query: 742 TTPPLRS 748
             PP RS
Sbjct: 573 PPPPSRS 579



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 107/448 (23%), Positives = 151/448 (33%), Gaps = 43/448 (9%)

Query: 419 PPKTSRTLEQPRATLAPSETPFV-PQKLEIFTSPEMQPTTPAPQQTTSI--PSTPKRRPR 475
           P   +  L  PR   +P   P V P  L +  +       P  ++   I   + P+  PR
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 476 PKPPRT-------KPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVT 528
             P RT       + ER   A   +P    SP     T  PG      L+    +S E T
Sbjct: 77  AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR----ISAEET 132

Query: 529 HTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 588
               A  +   AP +   S   R   + P P  P    A+   +   EV    PAP    
Sbjct: 133 ---VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189

Query: 589 LPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE-------LQTTLEETDQSTQEPFT 641
            P    P  S S  +   T          PSP+          LQ     +  S+  P +
Sbjct: 190 RPPTEGPRKSVSSASEHSTT--------EPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241

Query: 642 TKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKK 701
           +          T +AP       +P+      +RP     PR   A     + S+ P   
Sbjct: 242 SPARSGPSARGTPRAPAH---PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS-PLAT 297

Query: 702 PGTRRPPLPPRP----THPRRKPLPPNNVTGKPGSAGIISSGP-ITTPPLR--STPRPTG 754
           P    PP P  P    T P     PP+  T   GS  + ++   + +PPL   +TP P  
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 755 TPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPC 814
            P   +      P+ PAS       T    +P      L +  F  P    +Q P + P 
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 815 SITDSVKRFPKEEATEGNATSPPQNPPT 842
           S   S    P  +A    A  P Q PP+
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPS 445


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 112/520 (21%), Positives = 172/520 (33%), Gaps = 49/520 (9%)

Query: 261  THKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNE------ 314
            T KD+  +   +P  G  +  +  P   E T  + A + F   D L   +   E      
Sbjct: 842  TVKDALDAALPSPEEGTSIAAVPAP---EGTAVVAALVPFPHEDILVASIVSLEEEDVTA 898

Query: 315  -TLALPAESKTPEVE-KISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKP-W--I 369
              ++ P  +  P V   +      V   + P  T P  ++A+     +  +   P W  +
Sbjct: 899  AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAAL 958

Query: 370  VPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQP 429
              T  I+E+    +          +P   +EP+ +    +T +    + P     T E+P
Sbjct: 959  AITVPITEEDGTPEGPVTPATTVHAP---EEPDTAAVRVSTPEE--PASPAAAVPTPEEP 1013

Query: 430  RATLAPSETPFVPQKLEIFTSPEMQPTTPA-----PQQTTSIPS---TPKRRPRPKPPRT 481
             +  A   TP  P        P  +PT+PA     P++ TS  +   TP+    P     
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1073

Query: 482  KPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAP 541
             PE  TS     P   +   P    P P +       P  P +   T  +PA        
Sbjct: 1074 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-------PTSPAAAVPTPEEPASPAAAVPT 1126

Query: 542  PKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSE 601
            P+   SP   +P T   P  P      P+ S S  V+  TP          P P  S S 
Sbjct: 1127 PEEPASPAAAVP-TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASF 1185

Query: 602  PAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFY 661
             A + T   P  P  S  P+   +  TLEE            +P + E A    A     
Sbjct: 1186 AAVVATLEEPTSPAAS-VPTPAAMVATLEEFTSP-----AASVPTSEEPASLAAA----- 1234

Query: 662  TTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKK-PGTRRPPLPPRPTHPRRKP 720
                P     P       + P  S A      + + P    P    P  P        +P
Sbjct: 1235 -VSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293

Query: 721  LPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERI 760
              P      P  A  I +  + TP + + P     P+E +
Sbjct: 1294 ASPAAAVPTPEVAA-IPAASVPTPEVPAIPAAAVPPMEEV 1332



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 56/274 (20%), Positives = 85/274 (31%), Gaps = 23/274 (8%)

Query: 575  PEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQ 634
            P  +   P  KD L    P PE   S  A     G   +  + P P ++ L  ++   ++
Sbjct: 834  PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE 893

Query: 635  STQEPFTTKIP-RTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSV 693
                      P R T  A T   P    T      S      P V  A    G     +V
Sbjct: 894  EDVTAAAVSAPERATVPAVTVSVPEG--TAAVAAVSSPEETAPAVAAAITQEGMS---AV 948

Query: 694  DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPT 753
                P         P+      P   P+ P      P         P T     STP   
Sbjct: 949  AGFSPEWAALAITVPITEEDGTP-EGPVTPATTVHAP-------EEPDTAAVRVSTPEEP 1000

Query: 754  GTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSP 813
             +P   + T  ++PT PA+        +  +SP     P  +P      V   ++P +  
Sbjct: 1001 ASPAAAVPTP-EEPTSPAAAVP---TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056

Query: 814  CSITDSVKRFPKEEATEGNATSPPQNPPTNLTVV 847
             ++       P+E  +   A   P+ P +    V
Sbjct: 1057 AAVPT-----PEEPTSPAAAVPTPEEPTSPAAAV 1085


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 85/308 (27%), Positives = 122/308 (39%), Gaps = 36/308 (11%)

Query: 322 SKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSET-TLASSEKPWIVP----TAKIS 376
           S TP +   S  P T+TP + P  T P++   L  S T TL  S  P + P    T   S
Sbjct: 5   SNTPTLTPSS--PPTLTPSSTPTLT-PSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61

Query: 377 EDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPS 436
               +    T T    S+PT + +P ++ S T T   +  S PP           TL PS
Sbjct: 62  NTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPT---LTPSSPP-----------TLTPS 107

Query: 437 ETPFVPQKLEIFTSPEMQPT-TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK 495
            TP +        +P   PT TP+   T +  STP   P  +P  T+    T   +  P 
Sbjct: 108 NTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPI 167

Query: 496 ISKSPEPTWT-------TPAPGKTQFISLKPKI-PLSPEVTHTKPAPKQTPRAPPKPKTS 547
           +++S  PT T       TP+   T   S  P + P S  +      P  TP + P    S
Sbjct: 168 LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPS 227

Query: 548 PRPRI-PQTQPVPKVPQRVTAKPKTSPSPEVSYT---TPAPKDVLLPHKPYPEVSQSEPA 603
             P + P ++P+       T  P ++P+   S T   TP+    L P    P ++ S   
Sbjct: 228 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNT-PTLTPSSTP 286

Query: 604 PLETRGIP 611
            L     P
Sbjct: 287 TLTPSSTP 294



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 87/330 (26%), Positives = 128/330 (38%), Gaps = 37/330 (11%)

Query: 432 TLAPSETPFVPQKLEIFTSPEMQPT-TPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAG 490
           TL PS TP +        +P   PT TP+ Q   +  STP   P   P  T     T   
Sbjct: 1   TLTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60

Query: 491 TITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRP 550
           + TP ++ S  PT T   P  T  ++ +P +  S         P  TP +PP    S  P
Sbjct: 61  SNTPTLTPSSTPTLT---PSSTPTLTPQPILTRS-------STPTLTPSSPPTLTPSNTP 110

Query: 551 RI-PQTQPVPKVPQRVTAKPKTSPSPEVSYT---TPAPKDVLLPHKPYPEVSQSEPAPLE 606
            + P   P        T  P ++P+   S T   TP+ + + L     P ++ S   P+ 
Sbjct: 111 TLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPI-LTRSSTPTLTPSS-RPIL 168

Query: 607 TRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRP 666
           TR     P ++PS +      T   T   T     T  P +  +   +  P     T+ P
Sbjct: 169 TRS--STPTLTPSSTP---TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP-----TLTP 218

Query: 667 RTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNV 726
             S +P + P     P  + + R +   S+ PT  P +  P L P  T       P N  
Sbjct: 219 --SSRPILTP--SSTPTLTPSSRPILTRSSTPTLTPSS-TPTLTPSNTPTL---TPSNTP 270

Query: 727 TGKPGSAGIISSGPITTPPLRSTPRPTGTP 756
           T  P +   ++  P +TP L  +  PT TP
Sbjct: 271 TLTPSNTPTLT--PSSTPTLTPSSTPTLTP 298



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 51/179 (28%), Positives = 69/179 (38%), Gaps = 9/179 (5%)

Query: 336 TVTPETVPRSTKPTTSSALDVSETTLASSEKPWIV----PTAKISEDSKVLQPQTATYDV 391
           T+TP   P  T  +T +    S  TL  S +P +     PT   S    + +  T T   
Sbjct: 119 TLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTP 178

Query: 392 FSSPTT--SDEPEISDSYTATSDRILDSIPPKTSRTLEQP--RATLAPSETP-FVPQKLE 446
            S+PT   S  P ++ S T T       I  ++S     P  R  L PS TP   P    
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238

Query: 447 IFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWT 505
           I T       TP+   T +  +TP   P   P  T     T   + TP ++ S  PT T
Sbjct: 239 ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLT 297



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 80/326 (24%), Positives = 108/326 (33%), Gaps = 51/326 (15%)

Query: 534 PKQTPRAPPKPKTSPRPRI-PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHK 592
           P  TP +PP    S  P + P +QP+       T  P + P+      TP+    L P  
Sbjct: 8   PTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPT-----LTPSNTPTLTPSN 62

Query: 593 PYPEVSQSEPA--PLETRGIPFIPMISPSPSQEELQT-TLEETDQSTQEPFTTKIPRTTE 649
                  S P   P  T      P ++P P      T TL  +   T  P  T  P  T 
Sbjct: 63  TPTLTPSSTPTLTPSST------PTLTPQPILTRSSTPTLTPSSPPTLTPSNT--PTLTP 114

Query: 650 LAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPL 709
               T  P    T      S  P + P       PS   R +   S+ PT  P +R  P+
Sbjct: 115 SNTPTLTPSNTPTLT---PSSTPTLTPSSTPTLTPSS--RPILTRSSTPTLTPSSR--PI 167

Query: 710 PPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLER-IETDIKQPT 768
             R + P   P     +T            P +TP L  +  PT TP  R I T    PT
Sbjct: 168 LTRSSTPTLTPSSTPTLT------------PSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215

Query: 769 VPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEA 828
           +  S      I   SS+PT             P  R I    ++P     S         
Sbjct: 216 LTPSSRP---ILTPSSTPTLT-----------PSSRPILTRSSTPTLTPSSTPTLTPSNT 261

Query: 829 TEGNATSPPQNPPTNLTVVTVEGCPS 854
                ++ P   P+N   +T    P+
Sbjct: 262 PTLTPSNTPTLTPSNTPTLTPSSTPT 287



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 44/162 (27%), Positives = 70/162 (43%), Gaps = 19/162 (11%)

Query: 324 TPEVEKISARPTT--VTPETVPRSTKPTTSSALDVSETTLASSEKPWIVP--TAKISEDS 379
           TP    I  R +T  +TP + P  T+ +T +    S  TL  S  P + P  T  ++  S
Sbjct: 145 TPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 204

Query: 380 KVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILD-----SIPPKTSRTLEQPRA-TL 433
           + +  +++T  +  S      P  + + T +S  IL      ++ P ++ TL      TL
Sbjct: 205 RPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTL 264

Query: 434 APSETPFVPQKLEIFTSPEMQPT-TPAPQQTTSIPSTPKRRP 474
            PS TP +        +P   PT TP+   T +  STP   P
Sbjct: 265 TPSNTPTL--------TPSNTPTLTPSSTPTLTPSSTPTLTP 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,688,890
Number of Sequences: 37866
Number of extensions: 3237302
Number of successful extensions: 31694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 316
Number of HSP's successfully gapped in prelim test: 1582
Number of HSP's that attempted gapping in prelim test: 13725
Number of HSP's gapped (non-prelim): 9461
length of query: 1075
length of database: 18,247,518
effective HSP length: 113
effective length of query: 962
effective length of database: 13,968,660
effective search space: 13437850920
effective search space used: 13437850920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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