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Search of human proteins with 33620749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33620749 G2/M-phase specific E3 ubiquitin ligase [Homo
sapiens]
(706 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33620749 G2/M-phase specific E3 ubiquitin ligase [Homo sapiens] 1477 0.0
gi|21361543 PHD finger protein 7 isoform 1 [Homo sapiens] 261 2e-69
gi|27894287 PHD finger protein 7 isoform 2 [Homo sapiens] 207 3e-53
gi|28557677 PHD finger protein 6 isoform 1 [Homo sapiens] 83 1e-15
gi|62865858 PHD finger protein 6 isoform 1 [Homo sapiens] 83 1e-15
gi|63478060 PHD finger protein 6 isoform 2 [Homo sapiens] 83 1e-15
gi|94681069 PHD finger protein 11 isoform b [Homo sapiens] 65 2e-10
gi|94681065 PHD finger protein 11 isoform a [Homo sapiens] 65 2e-10
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 58 3e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 55 2e-07
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 55 2e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 54 6e-07
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 53 1e-06
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 50 7e-06
gi|40807477 retinoic acid induced 1 [Homo sapiens] 49 2e-05
gi|114520609 neural precursor cell expressed, developmentally do... 41 0.004
gi|114520607 neural precursor cell expressed, developmentally do... 41 0.004
gi|87116668 hypothetical protein LOC9870 [Homo sapiens] 39 0.017
gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens] 35 0.18
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 35 0.18
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 35 0.18
gi|167830431 zinc finger protein 530 [Homo sapiens] 35 0.24
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 34 0.41
gi|197384097 zinc finger protein 662 isoform 2 [Homo sapiens] 34 0.41
gi|46559763 zinc finger protein 662 isoform 1 [Homo sapiens] 34 0.41
gi|118498337 HECT domain containing 1 [Homo sapiens] 33 0.69
gi|40556370 PHD finger protein 15 [Homo sapiens] 33 0.91
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 33 0.91
gi|187960100 ubiquitin protein ligase E3C [Homo sapiens] 33 1.2
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 33 1.2
>gi|33620749 G2/M-phase specific E3 ubiquitin ligase [Homo sapiens]
Length = 706
Score = 1477 bits (3823), Expect = 0.0
Identities = 706/706 (100%), Positives = 706/706 (100%)
Query: 1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 60
MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG
Sbjct: 1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 60
Query: 61 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 120
VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF
Sbjct: 61 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 120
Query: 121 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 180
ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI
Sbjct: 121 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 180
Query: 181 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC 240
NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC
Sbjct: 181 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC 240
Query: 241 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK 300
KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK
Sbjct: 241 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK 300
Query: 301 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK 360
HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK
Sbjct: 301 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK 360
Query: 361 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL 420
TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL
Sbjct: 361 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL 420
Query: 421 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE 480
ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE
Sbjct: 421 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE 480
Query: 481 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV 540
NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV
Sbjct: 481 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV 540
Query: 541 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT 600
KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT
Sbjct: 541 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT 600
Query: 601 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF 660
VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF
Sbjct: 601 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF 660
Query: 661 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH 706
PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH
Sbjct: 661 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH 706
>gi|21361543 PHD finger protein 7 isoform 1 [Homo sapiens]
Length = 381
Score = 261 bits (667), Expect = 2e-69
Identities = 129/285 (45%), Positives = 171/285 (60%), Gaps = 6/285 (2%)
Query: 1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 60
+ + KP S C C + P K GE K+ N++VHY+CL++SS + QRG+ G
Sbjct: 22 VTQRKP--SSGPVCWLCLREPGDPEKLGEFLQKD--NISVHYFCLILSSKLPQRGQSNRG 77
Query: 61 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 120
+GFL EDI+KE RAS+ C VCKK GA+I C +C R++H PCG +R C+ QF G +
Sbjct: 78 FHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEY 137
Query: 121 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 180
SFC HRP Q I + E C +C E + NI +SPCC A +HR C+Q A
Sbjct: 138 KSFCDKHRPTQNIQHGHVGEE-SCILCCEDLSQQSVENI-QSPCCSQAIYHRKCIQKYAH 195
Query: 181 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC 240
+ FF+C CNN F +EMLRMGIHIP++DA+WELE A+ +L Q Y+ CD C
Sbjct: 196 TSAKHFFKCPQCNNRKEFPQEMLRMGIHIPDRDAAWELEPGAFSDLYQRYQHCDAPICLY 255
Query: 241 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLEC 285
++GRD + +W + C CGS GTH CSSLRS + WEC EC
Sbjct: 256 EQGRDSFEDEGRWCLILCATCGSHGTHRDCSSLRSNSKKWECEEC 300
>gi|27894287 PHD finger protein 7 isoform 2 [Homo sapiens]
Length = 342
Score = 207 bits (527), Expect = 3e-53
Identities = 114/285 (40%), Positives = 147/285 (51%), Gaps = 45/285 (15%)
Query: 1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 60
+ + KP S C C + P K GE K+ N++VHY+CL++SS + QRG+ G
Sbjct: 22 VTQRKP--SSGPVCWLCLREPGDPEKLGEFLQKD--NISVHYFCLILSSKLPQRGQSNRG 77
Query: 61 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 120
+GFL EDI+KE RAS+ C VCKK GA+I C +C R++H PCG +R C+ QF G +
Sbjct: 78 FHGFLPEDIKKEAARASRKICFVCKKKGAAINCQKDQCLRNFHLPCGQERGCLSQFFGEY 137
Query: 121 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 180
SFC HRP Q I + E C +C E + NI +SPCC A +HR C+Q A
Sbjct: 138 KSFCDKHRPTQNIQHGHVGEE-SCILCCEDLSQQSVENI-QSPCCSQAIYHRKCIQKYAH 195
Query: 181 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC 240
+ FF+C CNN F +EMLRMGIHI
Sbjct: 196 TSAKHFFKCPQCNNRKEFPQEMLRMGIHI------------------------------- 224
Query: 241 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLEC 285
PD +W + C CGS GTH CSSLRS + WEC EC
Sbjct: 225 --------PDRRWCLILCATCGSHGTHRDCSSLRSNSKKWECEEC 261
>gi|28557677 PHD finger protein 6 isoform 1 [Homo sapiens]
Length = 365
Score = 82.8 bits (203), Expect = 1e-15
Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 3 ESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVY 62
E K G ++ C FC+ + D + G+ E + H+ C+L SS + + E +
Sbjct: 6 EQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLG 63
Query: 63 GFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ---FTGN 119
GF IED++KE+ R +KL C +C GA+IGC C R+YH+ C L + + G
Sbjct: 64 GFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGI 123
Query: 120 FASFCWDHR 128
+ +C H+
Sbjct: 124 YMVYCRKHK 132
Score = 68.6 bits (166), Expect = 2e-11
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 5/130 (3%)
Query: 2 NESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGV 61
+ S P D++ C FC ++ G+ HY C+L SSG Q
Sbjct: 201 HRSSPSDTRP-KCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAE 259
Query: 62 YG-FLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIF---QFT 117
+G F I+ + +E+ R ++KC +C + GA+IGC C ++YH+ CG+Q + +
Sbjct: 260 FGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSR 319
Query: 118 GNFASFCWDH 127
G + +C +H
Sbjct: 320 GIYKLYCKNH 329
>gi|62865858 PHD finger protein 6 isoform 1 [Homo sapiens]
Length = 365
Score = 82.8 bits (203), Expect = 1e-15
Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 3 ESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVY 62
E K G ++ C FC+ + D + G+ E + H+ C+L SS + + E +
Sbjct: 6 EQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLG 63
Query: 63 GFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ---FTGN 119
GF IED++KE+ R +KL C +C GA+IGC C R+YH+ C L + + G
Sbjct: 64 GFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGI 123
Query: 120 FASFCWDHR 128
+ +C H+
Sbjct: 124 YMVYCRKHK 132
Score = 68.6 bits (166), Expect = 2e-11
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 5/130 (3%)
Query: 2 NESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGV 61
+ S P D++ C FC ++ G+ HY C+L SSG Q
Sbjct: 201 HRSSPSDTRP-KCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAE 259
Query: 62 YG-FLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIF---QFT 117
+G F I+ + +E+ R ++KC +C + GA+IGC C ++YH+ CG+Q + +
Sbjct: 260 FGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSR 319
Query: 118 GNFASFCWDH 127
G + +C +H
Sbjct: 320 GIYKLYCKNH 329
>gi|63478060 PHD finger protein 6 isoform 2 [Homo sapiens]
Length = 312
Score = 82.8 bits (203), Expect = 1e-15
Identities = 41/129 (31%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 3 ESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVY 62
E K G ++ C FC+ + D + G+ E + H+ C+L SS + + E +
Sbjct: 6 EQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSDNESLG 63
Query: 63 GFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ---FTGN 119
GF IED++KE+ R +KL C +C GA+IGC C R+YH+ C L + + G
Sbjct: 64 GFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGI 123
Query: 120 FASFCWDHR 128
+ +C H+
Sbjct: 124 YMVYCRKHK 132
Score = 33.9 bits (76), Expect = 0.53
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 2 NESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGV 61
+ S P D++ C FC ++ G+ HY C+L SSG Q
Sbjct: 202 HRSSPSDTRP-KCGFCHVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAE 260
Query: 62 YG-FLIEDIRKEVNRASKLKC 81
+G F I+ + +E+ R ++ C
Sbjct: 261 FGDFDIKTVLQEIKRGKRMVC 281
>gi|94681069 PHD finger protein 11 isoform b [Homo sapiens]
Length = 292
Score = 65.5 bits (158), Expect = 2e-10
Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 7/121 (5%)
Query: 23 CPN--KYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEE--EGVYGFLIEDIRKEVNRASK 78
CP +Y + N+ H CLL SSG+ + ++ F +E ++KE+ R K
Sbjct: 9 CPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRK 68
Query: 79 LKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ---FTGNFASFCWDHRPVQIITS 135
LKC C K GA++GC C ++YHF C + + + Q G + C H II
Sbjct: 69 LKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQ 128
Query: 136 N 136
+
Sbjct: 129 S 129
>gi|94681065 PHD finger protein 11 isoform a [Homo sapiens]
Length = 331
Score = 65.5 bits (158), Expect = 2e-10
Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 7/121 (5%)
Query: 23 CPN--KYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEE--EGVYGFLIEDIRKEVNRASK 78
CP +Y + N+ H CLL SSG+ + ++ F +E ++KE+ R K
Sbjct: 48 CPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRK 107
Query: 79 LKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ---FTGNFASFCWDHRPVQIITS 135
LKC C K GA++GC C ++YHF C + + + Q G + C H II
Sbjct: 108 LKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQ 167
Query: 136 N 136
+
Sbjct: 168 S 168
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 58.2 bits (139), Expect = 3e-08
Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 18/139 (12%)
Query: 6 PGDSQNLACVFCRKH-DDCPNKYGEKKT--KEKWNLTVHYYCLLMSSGIWQRGKEEEGVY 62
PG N C C + DD N G + +W H C L S+ +++ +++G
Sbjct: 1865 PGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWT---HVNCALWSAEVFE---DDDGS- 1917
Query: 63 GFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFAS 122
++++ V R +L+C C+K GA++GC C +YHF C + C+ F +
Sbjct: 1918 ---LKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCV--FLDDKKV 1972
Query: 123 FCWDHRPV---QIITSNNY 138
+C HR + +++ N +
Sbjct: 1973 YCQRHRDLIKGEVVPENGF 1991
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 55.5 bits (132), Expect = 2e-07
Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 9/114 (7%)
Query: 14 CVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEV 73
C C K+ D +K + N H C + S+ +++ E +G ++++ V
Sbjct: 1581 CALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE---ENDGS----LKNVHAAV 1633
Query: 74 NRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDH 127
R +++C +C K GA++GC C ++HF C CIFQ + FC H
Sbjct: 1634 ARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQ--DDKKVFCQKH 1685
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 55.1 bits (131), Expect = 2e-07
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 7/101 (6%)
Query: 14 CVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEV 73
C FC + D + +L VH C L S+ ++ E G LI ++ +
Sbjct: 4402 CCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVY------ETQAGALI-NVELAL 4454
Query: 74 NRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIF 114
R ++KC C K GA+ GC RC YHF C ++ +C+F
Sbjct: 4455 RRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMF 4495
Score = 50.4 bits (119), Expect = 5e-06
Identities = 54/246 (21%), Positives = 88/246 (35%), Gaps = 42/246 (17%)
Query: 41 HYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKR 100
H+ C+ S G+ Q + L+ ++ K V S +C CK GA+I C +C +
Sbjct: 252 HHRCVEWSLGVCQMEEP-------LLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQ 304
Query: 101 SYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNIL 160
YH+PC F+ F C +H +E C +C + + +
Sbjct: 305 MYHYPCAAGAGTFQDFSHIFL-LCPEHIDQ---APERSKEDANCAVCDSPGDLLDQF--F 358
Query: 161 RSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEE 220
+ C ++ +H CL DI + R G PE ++
Sbjct: 359 CTTCGQH--YHGMCL--------------------DIAVTPLKRAGWQCPECKVCQNCKQ 396
Query: 221 NAYQELLQHYERCDV-RRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQN 279
+ + + CD C + + P + W+ K C+ C GT S W N
Sbjct: 397 SGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTR----SSSQWHHN 452
Query: 280 WECLEC 285
CL C
Sbjct: 453 --CLIC 456
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 53.5 bits (127), Expect = 6e-07
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Query: 14 CVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEV 73
C FC + D + +L VH C L S+ +++ G + ++ +
Sbjct: 5032 CCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYE-------TQGGALMNVEVAL 5084
Query: 74 NRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIF 114
+R KC +C++ GA+ C RC YHF C ++ +C+F
Sbjct: 5085 HRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMF 5125
Score = 52.0 bits (123), Expect = 2e-06
Identities = 60/231 (25%), Positives = 89/231 (38%), Gaps = 48/231 (20%)
Query: 41 HYYCLLMSSGIW-QRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCK 99
H++C S+G+W Q G E GV + I + +C C + GASI C +P C
Sbjct: 139 HHWCAAWSAGVWGQEGPELCGVDKAIFSGISQ--------RCSHCTRLGASIPCRSPGCP 190
Query: 100 RSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSNN-----YRESLPCTICLEFIEPI 154
R YHFPC +G+F S + +Q++ + Y E C +C P
Sbjct: 191 RLYHFPCATA-------SGSFLSM----KTLQLLCPEHSEGAAYLEEARCAVC---EGPG 236
Query: 155 PSYNILRSPCCKNAWFHRDCLQVQAI---NAGVFFFRCTIC-------NNSDIFQKEMLR 204
++ C + +H CL AG C +C N+S + E
Sbjct: 237 ELCDLFFCTSCGH-HYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCD 295
Query: 205 MGIHIPEKDASWELEENAYQELLQHYERCDV-RRCR-CKEGRDYNAPDSKW 253
G H + +EL H +C R CR C G P+S+W
Sbjct: 296 KGYHT-------FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEW 339
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 40 VHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCK 99
VH C+L ++GI+ V G L +++ + A ++KC C++ GA++GC C
Sbjct: 1854 VHEGCILWANGIYL-------VCGRLY-GLQEALEIAREMKCSHCQEAGATLGCYNKGCS 1905
Query: 100 RSYHFPCGLQRECIFQFTGNFASFCWDHRP 129
YH+PC + +C+ NF+ C H+P
Sbjct: 1906 FRYHYPCAIDADCLLH-EENFSVRCPKHKP 1934
>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
Length = 1938
Score = 50.1 bits (118), Expect = 7e-06
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 9/89 (10%)
Query: 40 VHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCK 99
VH C+L ++GI+ V G L +++ + A ++KC C++ GA++GC C
Sbjct: 1854 VHEGCILWANGIYL-------VCGRLY-GLQEALEIAREMKCSHCQEAGATLGCYNKGCS 1905
Query: 100 RSYHFPCGLQRECIFQFTGNFASFCWDHR 128
YH+PC + +C+ NF+ C H+
Sbjct: 1906 FRYHYPCAIDADCLLH-EENFSVRCPKHK 1933
>gi|40807477 retinoic acid induced 1 [Homo sapiens]
Length = 1906
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 16/114 (14%)
Query: 18 RKHD---DCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVN 74
RKH+ + P + G + +E W VH C + + G++ V G L +++ +
Sbjct: 1803 RKHECSKEAPAEPGGE-AQEHW---VHEACAVWTGGVYL-------VAGKLF-GLQEAMK 1850
Query: 75 RASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHR 128
A + C C++ GA+IGC C +YH+PC CIF NF+ C H+
Sbjct: 1851 VAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCASDAGCIF-IEENFSLKCPKHK 1903
>gi|114520609 neural precursor cell expressed, developmentally
down-regulated 4 isoform 1 [Homo sapiens]
Length = 900
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/321 (20%), Positives = 131/321 (40%), Gaps = 39/321 (12%)
Query: 402 GSEHPGSKQEFLSLLMQHLENS--SLFEGSLSKNLSL----NSQALKEN--LYYE-AGKM 452
G ++ G +E+ L+ + + N LFE S + N +L NS E+ Y++ G++
Sbjct: 582 GLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRV 641
Query: 453 LAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKS 512
+++ HG GFF + + +++ P + S++ + I N T + DL+
Sbjct: 642 AGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTEL-DLRF 700
Query: 513 IINE-----CYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLG 567
II+E + + G ++ T +K + ++ + + R+ +FK+G L
Sbjct: 701 IIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELI 760
Query: 568 VLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHTLPDVKALGFWNSYLQAVEDGKSTT 627
+ I+ + E +L + E HT K +++ Q ++
Sbjct: 761 PQDLIKIFDENELELLMCGLGDVDVNDWRE----HT----KYKNGYSANHQVIQWFWKAV 812
Query: 628 TMED------ILIFATGCSSIPPAGFKP---TPSIECLHVD-------FPVGNKCNNCLA 671
M D +L F TG S +P GF + + V+ P + C N L
Sbjct: 813 LMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLD 872
Query: 672 IPITNTYKEFQENMDFTIRNT 692
+P +++E + + I NT
Sbjct: 873 LPPYESFEELWDKLQMAIENT 893
>gi|114520607 neural precursor cell expressed, developmentally
down-regulated 4 isoform 2 [Homo sapiens]
Length = 1247
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/321 (20%), Positives = 131/321 (40%), Gaps = 39/321 (12%)
Query: 402 GSEHPGSKQEFLSLLMQHLENS--SLFEGSLSKNLSL----NSQALKEN--LYYE-AGKM 452
G ++ G +E+ L+ + + N LFE S + N +L NS E+ Y++ G++
Sbjct: 929 GLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRV 988
Query: 453 LAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKS 512
+++ HG GFF + + +++ P + S++ + I N T + DL+
Sbjct: 989 AGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTEL-DLRF 1047
Query: 513 IINE-----CYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLG 567
II+E + + G ++ T +K + ++ + + R+ +FK+G L
Sbjct: 1048 IIDEELFGQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELI 1107
Query: 568 VLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHTLPDVKALGFWNSYLQAVEDGKSTT 627
+ I+ + E +L + E HT K +++ Q ++
Sbjct: 1108 PQDLIKIFDENELELLMCGLGDVDVNDWRE----HT----KYKNGYSANHQVIQWFWKAV 1159
Query: 628 TMED------ILIFATGCSSIPPAGFKP---TPSIECLHVD-------FPVGNKCNNCLA 671
M D +L F TG S +P GF + + V+ P + C N L
Sbjct: 1160 LMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLD 1219
Query: 672 IPITNTYKEFQENMDFTIRNT 692
+P +++E + + I NT
Sbjct: 1220 LPPYESFEELWDKLQMAIENT 1240
>gi|87116668 hypothetical protein LOC9870 [Homo sapiens]
Length = 823
Score = 38.9 bits (89), Expect = 0.017
Identities = 73/360 (20%), Positives = 141/360 (39%), Gaps = 44/360 (12%)
Query: 364 LYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENS 423
L +++ + S+L A RNF+ S + V+ D + G ++E+ L+ + L ++
Sbjct: 464 LKVSRHALLESSLKA--TRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDT 521
Query: 424 SLFEGSLSKNLSLNSQAL-----------KENLYYEAGKMLAISLVHGGPSPGF------ 466
+ L S N+QAL + +Y AG+++ L +
Sbjct: 522 T---NQLFTRFSDNNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRA 578
Query: 467 -FSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYN------ 519
F+++ ++ + + D +F +++ +N + +L E YN
Sbjct: 579 RFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELV-FAEEKYNKSGQLD 637
Query: 520 -YLELI-GCLRLITTLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPE 577
+EL+ G + T ++K + + Y + +V E F +GL L + + E
Sbjct: 638 KVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDE 697
Query: 578 AFCSILCHKPESLSAKILSELFTVHTLPDVKALGFWNSYLQAVEDGKSTTTMEDI---LI 634
+L +S F H + + F ++ S+ T E++ L
Sbjct: 698 NELELLMCGTGDISVSD----FKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQ 753
Query: 635 FATGCSSIPPAGFKP-TPSIECL----HVDFPVGNKCNNCLAIPITNTYKEFQENMDFTI 689
F TG S +PP GF PS + + H P + C N L +P ++Y+E + I
Sbjct: 754 FTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAI 813
>gi|94536811 NEDD4-like ubiquitin-protein ligase 1 [Homo sapiens]
Length = 1606
Score = 35.4 bits (80), Expect = 0.18
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 8/123 (6%)
Query: 402 GSEHPGSKQEFLSLLMQHLENS--SLFEGSLSKNLSLN---SQALKEN---LYYEAGKML 453
G ++ G +EF LL Q L N LFE S + ++ A EN + +G++L
Sbjct: 1289 GLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRIL 1348
Query: 454 AISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQIIIRINTATTVADLKSI 513
++L+H FF++ + L+ P + + +F + ++ N T + DL
Sbjct: 1349 GLALIHQYLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFT 1408
Query: 514 INE 516
+NE
Sbjct: 1409 VNE 1411
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 35.4 bits (80), Expect = 0.18
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 17/115 (14%)
Query: 23 CPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASK---L 79
CP K G K VH C L + E+ +E I K + S L
Sbjct: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEK-------MEPITKVSHIPSSRWAL 313
Query: 80 KCCVC-KKNGASIGCVAPRCKRSYHFPC----GLQRECIFQFTG--NFASFCWDH 127
C +C +K GASI C C+ ++H C GL+ + I F S+C H
Sbjct: 314 VCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKH 368
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 35.4 bits (80), Expect = 0.18
Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 17/115 (14%)
Query: 23 CPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASK---L 79
CP K G K VH C L + E+ +E I K + S L
Sbjct: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEK-------MEPITKVSHIPSSRWAL 313
Query: 80 KCCVC-KKNGASIGCVAPRCKRSYHFPC----GLQRECIFQFTG--NFASFCWDH 127
C +C +K GASI C C+ ++H C GL+ + I F S+C H
Sbjct: 314 VCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKH 368
>gi|167830431 zinc finger protein 530 [Homo sapiens]
Length = 599
Score = 35.0 bits (79), Expect = 0.24
Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 26/150 (17%)
Query: 162 SPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLR-MGIHIPEKDASWELEE 220
S C K+ D ++ Q ++ G + C++C S I + ++R +H E+ +
Sbjct: 466 SECEKSFSCKTDLIRHQTVHTGERPYECSVCGKSFIRKTHLIRHQTVHTNERPYECDECG 525
Query: 221 NAYQE---LLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTH----LACSSL 273
+Y + LLQH RR E R Y C+ CG S T + ++
Sbjct: 526 KSYSQSSALLQH------RRVHTGE-RPY----------ECRECGKSFTRKNHLIQHKTV 568
Query: 274 RSWEQNWECLEC-RGIIYNSGEFQKAKKHV 302
+ E+ +EC EC + +SG + + HV
Sbjct: 569 HTGERPYECSECGKSFSQSSGLLRHRRVHV 598
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 34.3 bits (77), Expect = 0.41
Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Query: 241 KEGRDYNAPDSKWEIKRCQCCGSSGTHLAC----SSLRSWEQNWECLECRGIIYNSGEFQ 296
++G ++ P E RCQ S L C L+ E+ C CRG + + E
Sbjct: 845 QDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHP 904
Query: 297 KAKKHVLPNSN------NVGITDCLLEE--SSPKLPRQSPGS---QSKDLLRQGSKF 342
+ + V P+S + G+ C + SS PRQ P Q D +G K+
Sbjct: 905 EGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKY 961
>gi|197384097 zinc finger protein 662 isoform 2 [Homo sapiens]
Length = 452
Score = 34.3 bits (77), Expect = 0.41
Identities = 39/167 (23%), Positives = 65/167 (38%), Gaps = 42/167 (25%)
Query: 164 CCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLR-MGIHIPEKDASWELEENA 222
C K F C+ Q I++GV + C C + +++ ++R IH EK
Sbjct: 251 CGKAFSFRSHCIAHQRIHSGVKPYECQECAKAFVWKSNLIRHQRIHTGEKP--------- 301
Query: 223 YQELLQHYERCDVRRCRCKE-GRDYNAPDSKWEIKR---------CQCCGSSGTH----L 268
CKE G+ ++ S + +R C+ CG S T L
Sbjct: 302 ---------------FECKECGKGFSQNTSLTQHQRIHTGEKPYTCKECGKSFTRNPALL 346
Query: 269 ACSSLRSWEQNWECLEC-RGIIYNSGEFQKAKKHVLPNSNNVGITDC 314
+ + E+ +EC +C +G ++NS Q + H + TDC
Sbjct: 347 RHQRMHTGEKPYECKDCGKGFMWNSDLSQHQRVHTGDKPHE--CTDC 391
>gi|46559763 zinc finger protein 662 isoform 1 [Homo sapiens]
Length = 426
Score = 34.3 bits (77), Expect = 0.41
Identities = 39/167 (23%), Positives = 65/167 (38%), Gaps = 42/167 (25%)
Query: 164 CCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLR-MGIHIPEKDASWELEENA 222
C K F C+ Q I++GV + C C + +++ ++R IH EK
Sbjct: 225 CGKAFSFRSHCIAHQRIHSGVKPYECQECAKAFVWKSNLIRHQRIHTGEKP--------- 275
Query: 223 YQELLQHYERCDVRRCRCKE-GRDYNAPDSKWEIKR---------CQCCGSSGTH----L 268
CKE G+ ++ S + +R C+ CG S T L
Sbjct: 276 ---------------FECKECGKGFSQNTSLTQHQRIHTGEKPYTCKECGKSFTRNPALL 320
Query: 269 ACSSLRSWEQNWECLEC-RGIIYNSGEFQKAKKHVLPNSNNVGITDC 314
+ + E+ +EC +C +G ++NS Q + H + TDC
Sbjct: 321 RHQRMHTGEKPYECKDCGKGFMWNSDLSQHQRVHTGDKPHE--CTDC 365
>gi|118498337 HECT domain containing 1 [Homo sapiens]
Length = 2610
Score = 33.5 bits (75), Expect = 0.69
Identities = 32/144 (22%), Positives = 59/144 (40%), Gaps = 13/144 (9%)
Query: 552 VHTPFESFKQGLKTLGVLEKIQAYP-EAFCSILCHKPESLSAKILSELFTVHTLPDVKAL 610
+ E+F+ G + +EK+ ++ E ILC S +E +T P +
Sbjct: 2458 IQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGNQ---SPSWAAEDIINYTEPKLGYT 2514
Query: 611 GFWNSYLQAVED--GKSTTTMEDILIFATGCSSIPPAG-------FKPTPSIECLHVDFP 661
+L+ V G S+ + L F TGCS++PP G ++ +P
Sbjct: 2515 RDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYP 2574
Query: 662 VGNKCNNCLAIPITNTYKEFQENM 685
N C + L +P ++ + +E +
Sbjct: 2575 SVNTCVHYLKLPEYSSEEIMRERL 2598
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 33.1 bits (74), Expect = 0.91
Identities = 31/115 (26%), Positives = 43/115 (37%), Gaps = 17/115 (14%)
Query: 23 CPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASK---L 79
CP + G K VH C L + E+ +E I K + + L
Sbjct: 257 CPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEK-------MEPITKISHIPASRWAL 309
Query: 80 KCCVCKK-NGASIGCVAPRCKRSYHFPC----GLQRECIFQFTG--NFASFCWDH 127
C +CK+ G I C P C ++H C GL+ I F SFC +H
Sbjct: 310 SCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEH 364
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 33.1 bits (74), Expect = 0.91
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 17/111 (15%)
Query: 23 CPNKYG--EKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLK 80
CPNK G +K ++W H C L + V+ I+ +R KL
Sbjct: 274 CPNKGGAFKKTDDDRWG---HVVCALWIPEVGFANT----VFIEPIDGVRNIPPARWKLT 326
Query: 81 CCVCKKNG--ASIGCVAPRCKRSYHFPCG------LQRECIFQFTGNFASF 123
C +CK+ G A I C C ++H C ++ E + + TG +F
Sbjct: 327 CYLCKQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTF 377
>gi|187960100 ubiquitin protein ligase E3C [Homo sapiens]
Length = 1083
Score = 32.7 bits (73), Expect = 1.2
Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 19/154 (12%)
Query: 532 TLSDKYMLVKDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLS 591
T +++ + + Y + +++ +F+QGL + LE ++ + + +L +
Sbjct: 912 TSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPI 971
Query: 592 AKILSELFTVHT------LPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPA 645
+ + FT ++ P +K FW V +G + +L F T CS P
Sbjct: 972 SLEDLKSFTNYSGGYSADHPVIKV--FWR-----VVEGFTDEEKRKLLKFVTSCSRPPLL 1024
Query: 646 GFKPTPSIECLH------VDFPVGNKCNNCLAIP 673
GFK C+H P + C N L +P
Sbjct: 1025 GFKELYPAFCIHNGGSDLERLPTASTCMNLLKLP 1058
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 32.7 bits (73), Expect = 1.2
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 240 CKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECR 286
CKEG Y +PD+ E RC C S+ T S++S E EC +C+
Sbjct: 369 CKEGF-YQSPDATKECLRCPC--SAVTSTGSCSIKSSELEPECDQCK 412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,559,550
Number of Sequences: 37866
Number of extensions: 1420237
Number of successful extensions: 3520
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3468
Number of HSP's gapped (non-prelim): 72
length of query: 706
length of database: 18,247,518
effective HSP length: 109
effective length of query: 597
effective length of database: 14,120,124
effective search space: 8429714028
effective search space used: 8429714028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.