Guide to the Human Genome
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Name: NEDD4 Sequence: fasta or formatted (1247aa) NCBI GI: 114520607
Description:

neural precursor cell expressed, developmentally down-regulated 4 isoform 2

Referenced in:

Neurons
Ubiquitin and Related Protein Modifications
WW Domain

Other entries for this name:
alt prot [900aa] neural precursor cell expressed, developmentally down-regulated 4...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.2         52           2
 C cysteine            1.8         22           1
 D aspartate           5.5         68           2
 E glutamate           6.6         82           2
 F phenylalanine       4.0         50           2
 G glycine             5.9         73           2
 H histidine           2.6         32           1
 I isoleucine          4.8         60           2
 K lysine              5.0         62           2
 L leucine             8.3        104           2
 M methionine          1.7         21           2
 N asparagine          6.0         75           2
 P proline             5.9         74           3
 Q glutamine           4.8         60           4
 R arginine            5.9         74           2
 S serine             11.2        140           3
 T threonine           6.7         84           3
 V valine              4.5         56           2
 W tryptophan          1.5         19           1
 Y tyrosine            3.1         39           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neural precursor cell expressed, developmentally do... 
NEDD4                 0.594   neural precursor cell expressed, developmentally do...
NEDD4L                0.380   neural precursor cell expressed, developmentally dow...
NEDD4L                0.380   neural precursor cell expressed, developmentally do...
NEDD4L                0.380   neural precursor cell expressed, developmentally do...
NEDD4L                0.380   neural precursor cell expressed, developmentally do...
NEDD4L                0.379   neural precursor cell expressed, developmentally do...
NEDD4L                0.379   neural precursor cell expressed, developmentally do...
NEDD4L                0.379   neural precursor cell expressed, developmentally do...
NEDD4L                0.379   neural precursor cell expressed, developmentally do...
NEDD4L                0.379   neural precursor cell expressed, developmentally do...
ITCH                  0.198   itchy homolog E3 ubiquitin protein ligase 
WWP2                  0.196   WW domain containing E3 ubiquitin protein ligase 2 i...
WWP1                  0.193   WW domain containing E3 ubiquitin protein ligase 1 [...
SMURF2                0.183   SMAD specific E3 ubiquitin protein ligase 2 
HECW2                 0.170   HECT, C2 and WW domain containing E3 ubiquitin prote...
SMURF1                0.168   Smad ubiquitination regulatory factor 1 isoform 2 [H...
SMURF1                0.167   Smad ubiquitination regulatory factor 1 isoform 1 [H...
HECW1                 0.167   NEDD4-like ubiquitin-protein ligase 1 
WWP2                  0.165   WW domain containing E3 ubiquitin protein ligase 2 i...
HUWE1                 0.124   HECT, UBA and WWE domain containing 1 
HACE1                 0.102   HECT domain and ankyrin repeat containing, E3 ubiqu...
KIAA0317              0.078   hypothetical protein LOC9870 
UBE3A                 0.070   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.070   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.070   ubiquitin protein ligase E3A isoform 2 
HECTD2                0.068   HECT domain containing 2 isoform a 
UBE3C                 0.063   ubiquitin protein ligase E3C 
UBE3B                 0.063   ubiquitin protein ligase E3B 
UBE3B                 0.063   ubiquitin protein ligase E3B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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